row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:17400 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,400 | train | mutant | 4,901,767 | 341 | 4,908,353 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62D | N62D | 1 | 1 | 0 | 0 | 62 | N | D | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,600 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.18854 | 0.419997 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159882,"numValue":0.188540354245059,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159883,"numValue":0.419997103927544,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17401 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,401 | train | mutant | 4,901,768 | 341 | 4,908,354 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62E | N62E | 1 | 1 | 0 | 0 | 62 | N | E | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,601 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159884,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159885,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17402 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,402 | train | mutant | 4,901,769 | 341 | 4,908,355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62F | N62F | 1 | 1 | 0 | 0 | 62 | N | F | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,602 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159886,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159887,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17403 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,403 | train | mutant | 4,901,770 | 341 | 4,908,356 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62G | N62G | 1 | 1 | 0 | 0 | 62 | N | G | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,603 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159888,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159889,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17405 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,405 | train | mutant | 4,901,772 | 341 | 4,908,358 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62I | N62I | 1 | 1 | 0 | 0 | 62 | N | I | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,605 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.299138 | 0.391718 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159892,"numValue":-0.299137820412396,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159893,"numValue":0.391718066212756,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17406 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,406 | train | mutant | 4,901,773 | 341 | 4,908,359 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62K | N62K | 1 | 1 | 0 | 0 | 62 | N | K | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,606 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.349147 | 0.539934 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159894,"numValue":-0.34914695998055,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159895,"numValue":0.539933798397189,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17407 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,407 | train | mutant | 4,901,774 | 341 | 4,908,360 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62L | N62L | 1 | 1 | 0 | 0 | 62 | N | L | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,607 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159896,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159897,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17409 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,409 | train | mutant | 4,901,851 | 341 | 4,908,437 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62P | N62P | 1 | 1 | 0 | 0 | 62 | N | P | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,688 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160058,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160059,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17410 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,410 | train | mutant | 4,901,852 | 341 | 4,908,438 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62Q | N62Q | 1 | 1 | 0 | 0 | 62 | N | Q | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,689 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.152169 | 0.433003 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160060,"numValue":0.152169100933581,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160061,"numValue":0.433002977565154,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17411 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,411 | train | mutant | 4,901,853 | 341 | 4,908,439 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62R | N62R | 1 | 1 | 0 | 0 | 62 | N | R | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,690 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160062,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160063,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17413 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,413 | train | mutant | 4,901,855 | 341 | 4,908,441 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62T | N62T | 1 | 1 | 0 | 0 | 62 | N | T | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,692 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160066,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160067,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17414 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,414 | train | mutant | 4,901,856 | 341 | 4,908,442 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62V | N62V | 1 | 1 | 0 | 0 | 62 | N | V | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,693 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160068,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160069,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17415 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,415 | train | mutant | 4,901,857 | 341 | 4,908,443 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | N62W | N62W | 1 | 1 | 0 | 0 | 62 | N | W | 5 | CONSERVATION | 1C9O | 231 | null | 62 | A|B | E | true | true | 31.211666 | 12.28875 | 5,083,694 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160070,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160071,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":20804,"numValue":5.0,"position":62,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17417 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,417 | train | mutant | 4,901,776 | 341 | 4,908,362 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delV63 | delV63 | 1 | 0 | 1 | 0 | 63 | V | - | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,609 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.134868 | 0.13681 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159900,"numValue":-1.13486781031796,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159901,"numValue":0.136809510820143,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17418 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,418 | train | mutant | 4,901,776 | 341 | 4,908,362 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delV63 | delV63 | 1 | 0 | 1 | 0 | 63 | V | - | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,627 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.770251 | 0.148205 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159936,"numValue":-0.770250708401187,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159937,"numValue":0.148204825194947,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17419 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,419 | train | mutant | 4,901,777 | 341 | 4,908,363 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63A | V63A | 1 | 1 | 0 | 0 | 63 | V | A | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,610 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.204939 | 0.044085 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159902,"numValue":-0.204938775829998,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159903,"numValue":0.0440845695777332,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17420 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,420 | train | mutant | 4,901,778 | 341 | 4,908,364 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63C | V63C | 1 | 1 | 0 | 0 | 63 | V | C | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,611 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.008654 | 0.082646 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159904,"numValue":0.00865445904931001,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159905,"numValue":0.0826458752456201,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17422 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,422 | train | mutant | 4,901,780 | 341 | 4,908,366 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63E | V63E | 1 | 1 | 0 | 0 | 63 | V | E | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,613 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.782325 | 0.076925 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159908,"numValue":-0.782325219980011,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159909,"numValue":0.0769249814284423,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17423 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,423 | train | mutant | 4,901,781 | 341 | 4,908,367 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63F | V63F | 1 | 1 | 0 | 0 | 63 | V | F | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,614 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.013081 | 0.085082 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159910,"numValue":-1.01308078064815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159911,"numValue":0.0850820461908841,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17424 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,424 | train | mutant | 4,901,782 | 341 | 4,908,368 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63G | V63G | 1 | 1 | 0 | 0 | 63 | V | G | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,615 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.872861 | 0.061602 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159912,"numValue":-0.87286123513123,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159913,"numValue":0.0616021431274052,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17425 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,425 | train | mutant | 4,901,783 | 341 | 4,908,369 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63H | V63H | 1 | 1 | 0 | 0 | 63 | V | H | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,616 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.770863 | 0.102445 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159914,"numValue":-0.770862685354783,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159915,"numValue":0.10244472863442,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17426 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,426 | train | mutant | 4,901,784 | 341 | 4,908,370 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63I | V63I | 1 | 1 | 0 | 0 | 63 | V | I | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,617 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.126358 | 0.053786 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159916,"numValue":-0.126358065975766,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159917,"numValue":0.0537858150876157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17427 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,427 | train | mutant | 4,901,785 | 341 | 4,908,371 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63K | V63K | 1 | 1 | 0 | 0 | 63 | V | K | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,618 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.721333 | 0.0708 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159918,"numValue":-0.721333038384232,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159919,"numValue":0.0708004104460192,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17428 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,428 | train | mutant | 4,901,786 | 341 | 4,908,372 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63L | V63L | 1 | 1 | 0 | 0 | 63 | V | L | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,619 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.018035 | 0.030474 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159920,"numValue":-0.0180350627791274,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159921,"numValue":0.0304738085296935,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17429 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,429 | train | mutant | 4,901,787 | 341 | 4,908,373 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63M | V63M | 1 | 1 | 0 | 0 | 63 | V | M | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,620 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.282704 | 0.050168 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159922,"numValue":-0.282703832557391,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159923,"numValue":0.0501679548194202,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17430 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,430 | train | mutant | 4,901,788 | 341 | 4,908,374 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63N | V63N | 1 | 1 | 0 | 0 | 63 | V | N | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,621 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.52821 | 0.07317 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159924,"numValue":-0.528210325903914,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159925,"numValue":0.0731702502976108,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17431 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,431 | train | mutant | 4,901,789 | 341 | 4,908,375 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63P | V63P | 1 | 1 | 0 | 0 | 63 | V | P | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,622 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.642586 | 0.051742 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159926,"numValue":-0.642585522723392,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159927,"numValue":0.0517422898361649,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17432 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,432 | train | mutant | 4,901,790 | 341 | 4,908,376 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63Q | V63Q | 1 | 1 | 0 | 0 | 63 | V | Q | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,623 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.132578 | 0.175728 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159928,"numValue":-1.13257787601979,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159929,"numValue":0.175727724008139,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17433 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,433 | train | mutant | 4,901,791 | 341 | 4,908,377 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63R | V63R | 1 | 1 | 0 | 0 | 63 | V | R | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,624 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.710169 | 0.042007 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159930,"numValue":-0.710168608379271,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159931,"numValue":0.0420070074058296,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17435 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,435 | train | mutant | 4,901,793 | 341 | 4,908,379 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63T | V63T | 1 | 1 | 0 | 0 | 63 | V | T | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,626 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.432438 | 0.052717 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159934,"numValue":-0.432437829533811,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159935,"numValue":0.0527165329612268,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17436 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,436 | train | mutant | 4,901,849 | 341 | 4,908,435 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63W | V63W | 1 | 1 | 0 | 0 | 63 | V | W | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,686 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.773549 | 0.069511 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160054,"numValue":-0.773548887178609,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160055,"numValue":0.0695113702646062,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17437 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,437 | train | mutant | 4,901,850 | 341 | 4,908,436 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V63Y | V63Y | 1 | 1 | 0 | 0 | 63 | V | Y | 8 | CONSERVATION | 1C9O | 231 | null | 63 | A|B | E | false | true | 0.04926 | 10.776429 | 5,083,687 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.79811 | 0.082053 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160056,"numValue":-0.798110301237668,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160057,"numValue":0.0820532226320927,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20805,"numValue":8.0,"position":63,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17438 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,438 | train | mutant | 320 | 341 | 355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64T | V64T | 1 | 1 | 0 | 0 | 64 | V | T | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 565 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:V64T | 75.1 | -1.8 | null | null | null | null | 58.32 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:V64T... | [{"datasets":[],"id":2244,"numValue":75.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":2245,"numValue":-1.8,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":2246,"numValue":58.32,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"... | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17439 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,439 | train | mutant | 320 | 341 | 355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64T | V64T | 1 | 1 | 0 | 0 | 64 | V | T | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 4,183 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | null | 1C9O_A:V64T | 75.1 | -1.8 | null | null | null | null | 58.32 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:V64T"... | [{"datasets":[],"id":15514,"numValue":75.1,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":15515,"numValue":-1.8,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":15516,"numValue":58.32,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[... | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17440 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,440 | train | mutant | 320 | 341 | 355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64T | V64T | 1 | 1 | 0 | 0 | 64 | V | T | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 6,621 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | 1C9O_A:V64T | null | null | 0.81 | 0.26 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23628,"numValue":0.81,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","potapov_with_uniprot_mapping.csv"],"id":23629,"numValue":0.26,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23630,"numValue":null,"references":[],"strValue":"yes","type":"R... | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17441 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,441 | train | mutant | 320 | 341 | 355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64T | V64T | 1 | 1 | 0 | 0 | 64 | V | T | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 6,635 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:V64T | null | null | 2.01 | 0.19 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23670,"numValue":2.01,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23671,"numValue":0.19,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23672,"numValue":null,"reference... | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17443 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,443 | train | mutant | 320 | 341 | 355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64T | V64T | 1 | 1 | 0 | 0 | 64 | V | T | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 6,665 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | 1C9O_A:V64T | null | null | 2.01 | 0.19 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23756,"numValue":2.01,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23757,"numValue":0.19,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23758,"numValue":null,"reference... | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17444 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,444 | train | mutant | 320 | 341 | 355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64T | V64T | 1 | 1 | 0 | 0 | 64 | V | T | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 8,807 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | 1C9O_A:V64T | null | null | 0.88 | 0.31 | null | null | null | 2.5 | 1.79 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":[],"id":29789,"numValue":0.88,"references":[],"strValue":null,"type":"DG"},{"datasets":["potapov_with_uniprot_mapping.csv"],"id":29790,"numValue":0.31,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":29791,"numValue":1.79,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":2979... | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17445 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,445 | train | mutant | 320 | 341 | 355 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64T | V64T | 1 | 1 | 0 | 0 | 64 | V | T | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,644 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.011942 | 0.066874 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159970,"numValue":-0.0119419679457124,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159971,"numValue":0.0668741906163545,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17446 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,446 | train | mutant | 4,901,794 | 341 | 4,908,380 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64A | V64A | 1 | 1 | 0 | 0 | 64 | V | A | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,628 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.030082 | 0.043628 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159938,"numValue":-0.0300819512215335,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159939,"numValue":0.0436280231520354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17447 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,447 | train | mutant | 4,901,795 | 341 | 4,908,381 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64C | V64C | 1 | 1 | 0 | 0 | 64 | V | C | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,629 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.032422 | 0.070479 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159940,"numValue":0.0324216190206859,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159941,"numValue":0.0704785949790418,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17448 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,448 | train | mutant | 4,901,796 | 341 | 4,908,382 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64D | V64D | 1 | 1 | 0 | 0 | 64 | V | D | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,630 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.057056 | 0.071586 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159942,"numValue":-0.0570560032104961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159943,"numValue":0.0715858322433025,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17449 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,449 | train | mutant | 4,901,797 | 341 | 4,908,383 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64E | V64E | 1 | 1 | 0 | 0 | 64 | V | E | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,631 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.003088 | 0.055998 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159944,"numValue":-0.00308774501286697,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159945,"numValue":0.0559977940495209,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17450 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,450 | train | mutant | 4,901,798 | 341 | 4,908,384 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64F | V64F | 1 | 1 | 0 | 0 | 64 | V | F | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,632 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.011369 | 0.046342 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159946,"numValue":0.0113693509976553,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159947,"numValue":0.0463421563532859,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17451 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,451 | train | mutant | 4,901,799 | 341 | 4,908,385 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64G | V64G | 1 | 1 | 0 | 0 | 64 | V | G | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,633 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.041916 | 0.035486 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159948,"numValue":-0.0419160348147133,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159949,"numValue":0.035486358584532,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17452 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,452 | train | mutant | 4,901,800 | 341 | 4,908,386 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64H | V64H | 1 | 1 | 0 | 0 | 64 | V | H | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,634 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.057135 | 0.099499 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159950,"numValue":-0.0571348417758083,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159951,"numValue":0.0994994265331663,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17454 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,454 | train | mutant | 4,901,802 | 341 | 4,908,388 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64K | V64K | 1 | 1 | 0 | 0 | 64 | V | K | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,636 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.029302 | 0.06834 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159954,"numValue":-0.02930186436476,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159955,"numValue":0.0683399951599938,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17455 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,455 | train | mutant | 4,901,803 | 341 | 4,908,389 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64L | V64L | 1 | 1 | 0 | 0 | 64 | V | L | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,637 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.0154 | 0.038191 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159956,"numValue":-0.0153996021672622,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159957,"numValue":0.0381911319290435,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17456 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,456 | train | mutant | 4,901,804 | 341 | 4,908,390 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64M | V64M | 1 | 1 | 0 | 0 | 64 | V | M | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,638 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.063889 | 0.066308 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159958,"numValue":-0.0638894692324445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159959,"numValue":0.0663076199342085,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17457 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,457 | train | mutant | 4,901,805 | 341 | 4,908,391 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64N | V64N | 1 | 1 | 0 | 0 | 64 | V | N | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,639 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.019903 | 0.08714 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159960,"numValue":-0.0199028847287422,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159961,"numValue":0.087140206962467,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17458 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,458 | train | mutant | 4,901,806 | 341 | 4,908,392 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64P | V64P | 1 | 1 | 0 | 0 | 64 | V | P | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,640 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.730988 | 0.089266 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159962,"numValue":-0.730987858056255,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159963,"numValue":0.0892655879844739,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17459 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,459 | train | mutant | 4,901,807 | 341 | 4,908,393 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64Q | V64Q | 1 | 1 | 0 | 0 | 64 | V | Q | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,641 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.031746 | 0.088129 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159964,"numValue":0.0317464526606061,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159965,"numValue":0.0881290678245258,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17460 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,460 | train | mutant | 4,901,808 | 341 | 4,908,394 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64R | V64R | 1 | 1 | 0 | 0 | 64 | V | R | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,642 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.002841 | 0.035372 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159966,"numValue":-0.00284055943591062,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159967,"numValue":0.0353721078696577,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17461 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,461 | train | mutant | 4,901,809 | 341 | 4,908,395 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64S | V64S | 1 | 1 | 0 | 0 | 64 | V | S | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,643 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01858 | 0.039602 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159968,"numValue":-0.0185798194822997,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159969,"numValue":0.0396024430192306,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17462 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,462 | train | mutant | 4,901,847 | 341 | 4,908,433 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64W | V64W | 1 | 1 | 0 | 0 | 64 | V | W | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,684 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.041994 | 0.052797 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160050,"numValue":-0.0419942806088578,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160051,"numValue":0.0527965629965862,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17463 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,463 | train | mutant | 4,901,848 | 341 | 4,908,434 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | V64Y | V64Y | 1 | 1 | 0 | 0 | 64 | V | Y | 4 | CONSERVATION | 1C9O | 231 | null | 64 | A|B | E | false | false | 59.391957 | 14.858571 | 5,083,685 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.053818 | 0.059076 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160052,"numValue":-0.0538182870921857,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160053,"numValue":0.0590763985309809,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20806,"numValue":4.0,"position":64,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17464 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,464 | train | mutant | 4,901,810 | 341 | 4,908,396 | 66 | 65 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | delK65 | delK65 | 1 | 0 | 1 | 0 | 65 | K | - | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,645 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.016462 | 0.197198 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159972,"numValue":-1.01646206594329,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159973,"numValue":0.197197658595974,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17465 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,465 | train | mutant | 4,901,811 | 341 | 4,908,397 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65A | K65A | 1 | 1 | 0 | 0 | 65 | K | A | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,646 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.002129 | 0.050845 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159974,"numValue":0.00212864126342963,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159975,"numValue":0.0508452670111273,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17466 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,466 | train | mutant | 4,901,812 | 341 | 4,908,398 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65C | K65C | 1 | 1 | 0 | 0 | 65 | K | C | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,647 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.034664 | 0.049312 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159976,"numValue":-0.0346640723483257,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159977,"numValue":0.0493119161929216,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17467 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,467 | train | mutant | 4,901,813 | 341 | 4,908,399 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65D | K65D | 1 | 1 | 0 | 0 | 65 | K | D | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,648 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.018866 | 0.081647 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159978,"numValue":-0.0188661279563283,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159979,"numValue":0.0816468779965926,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17468 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,468 | train | mutant | 4,901,814 | 341 | 4,908,400 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65E | K65E | 1 | 1 | 0 | 0 | 65 | K | E | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,649 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.030367 | 0.084488 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159980,"numValue":-0.0303670741532265,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159981,"numValue":0.0844882080350212,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17469 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,469 | train | mutant | 4,901,815 | 341 | 4,908,401 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65F | K65F | 1 | 1 | 0 | 0 | 65 | K | F | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,650 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.097828 | 0.049983 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159982,"numValue":-0.0978279896714307,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159983,"numValue":0.049983484432013,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17470 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,470 | train | mutant | 4,901,816 | 341 | 4,908,402 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65G | K65G | 1 | 1 | 0 | 0 | 65 | K | G | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,651 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.022564 | 0.074017 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159984,"numValue":0.022563834500821,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159985,"numValue":0.074017379573458,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17471 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,471 | train | mutant | 4,901,817 | 341 | 4,908,403 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65H | K65H | 1 | 1 | 0 | 0 | 65 | K | H | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,652 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.014212 | 0.060387 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159986,"numValue":0.0142122815182369,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159987,"numValue":0.060387021510612,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17472 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,472 | train | mutant | 4,901,818 | 341 | 4,908,404 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65I | K65I | 1 | 1 | 0 | 0 | 65 | K | I | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,653 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.040435 | 0.076415 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159988,"numValue":0.0404346996664786,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159989,"numValue":0.0764151389470511,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17473 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,473 | train | mutant | 4,901,836 | 341 | 4,908,422 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65L | K65L | 1 | 1 | 0 | 0 | 65 | K | L | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,673 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.051962 | 0.036667 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160028,"numValue":-0.0519623205659262,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160029,"numValue":0.0366666134012375,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17474 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,474 | train | mutant | 4,901,837 | 341 | 4,908,423 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65M | K65M | 1 | 1 | 0 | 0 | 65 | K | M | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,674 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.07776 | 0.047866 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160030,"numValue":-0.0777603145580511,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160031,"numValue":0.0478660287605191,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17475 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,475 | train | mutant | 4,901,838 | 341 | 4,908,424 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65N | K65N | 1 | 1 | 0 | 0 | 65 | K | N | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,675 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.051234 | 0.057314 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160032,"numValue":-0.051233804800748,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160033,"numValue":0.0573140364998224,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17476 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,476 | train | mutant | 4,901,839 | 341 | 4,908,425 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65P | K65P | 1 | 1 | 0 | 0 | 65 | K | P | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,676 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.025329 | 0.063892 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160034,"numValue":0.025329111998426,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160035,"numValue":0.0638924330882833,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17477 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,477 | train | mutant | 4,901,840 | 341 | 4,908,426 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65Q | K65Q | 1 | 1 | 0 | 0 | 65 | K | Q | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,677 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.023199 | 0.060169 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160036,"numValue":-0.0231986924214932,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160037,"numValue":0.0601689409979928,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17478 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,478 | train | mutant | 4,901,841 | 341 | 4,908,427 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65R | K65R | 1 | 1 | 0 | 0 | 65 | K | R | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,678 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.004462 | 0.043804 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160038,"numValue":0.00446178857973675,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160039,"numValue":0.0438036197550612,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17479 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,479 | train | mutant | 4,901,842 | 341 | 4,908,428 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65S | K65S | 1 | 1 | 0 | 0 | 65 | K | S | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,679 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.015254 | 0.034982 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160040,"numValue":-0.0152543732311607,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160041,"numValue":0.0349823904654133,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17480 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,480 | train | mutant | 4,901,843 | 341 | 4,908,429 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65T | K65T | 1 | 1 | 0 | 0 | 65 | K | T | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,680 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.002905 | 0.054974 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160042,"numValue":-0.00290517149319661,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160043,"numValue":0.0549743864838049,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17481 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,481 | train | mutant | 4,901,844 | 341 | 4,908,430 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65V | K65V | 1 | 1 | 0 | 0 | 65 | K | V | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,681 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.014522 | 0.055706 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160044,"numValue":-0.0145223008389759,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160045,"numValue":0.0557063462494678,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17482 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,482 | train | mutant | 4,901,845 | 341 | 4,908,431 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65W | K65W | 1 | 1 | 0 | 0 | 65 | K | W | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,682 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.145313 | 0.054545 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160046,"numValue":-0.145313109607258,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160047,"numValue":0.0545451312426708,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17483 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,483 | train | mutant | 4,901,846 | 341 | 4,908,432 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | K65Y | K65Y | 1 | 1 | 0 | 0 | 65 | K | Y | 4 | CONSERVATION | 1C9O | 231 | null | 65 | A|B | E | false | false | 83.333641 | 19.506111 | 5,083,683 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.130003 | 0.047353 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160048,"numValue":-0.130003015886328,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160049,"numValue":0.0473528726883001,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20807,"numValue":4.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17484 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,484 | train | mutant | 321 | 341 | 356 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66E | L66E | 1 | 1 | 0 | 0 | 66 | L | E | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 566 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | null | 1C9O_A:L66E | 68.9 | -8 | null | null | null | null | 50.19 | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DHVH|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1C9O_A:L66E... | [{"datasets":[],"id":2248,"numValue":68.9,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":2249,"numValue":-8.0,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":2250,"numValue":50.19,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"... | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||
fireprotdb:17486 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,486 | train | mutant | 321 | 341 | 356 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66E | L66E | 1 | 1 | 0 | 0 | 66 | L | E | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 6,636 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:L66E | null | null | 0.93 | 1.27 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23673,"numValue":0.93,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23674,"numValue":1.27,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23675,"numValue":null,"reference... | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17487 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,487 | train | mutant | 321 | 341 | 356 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66E | L66E | 1 | 1 | 0 | 0 | 66 | L | E | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 6,666 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | 1C9O_A:L66E | null | null | 0.93 | 1.27 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | capriotti_S1615_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23759,"numValue":0.93,"references":[],"strValue":null,"type":"DG"},{"datasets":["capriotti_S1615_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":23760,"numValue":1.27,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23761,"numValue":null,"reference... | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:17488 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,488 | train | mutant | 321 | 341 | 356 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66E | L66E | 1 | 1 | 0 | 0 | 66 | L | E | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 8,808 | ProTherm | 7 | CD | GdnHCl | sodium cacodylate-HCl | 100 mM | 25 | 1C9O_A:L66E | null | null | 0.36 | 0.84 | null | null | null | 2.21 | 1.74 | null | null | null | null | null | null | null | yes | DG|DDG|M|CM|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"GdnHCl","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","typ... | [{"datasets":[],"id":29794,"numValue":0.36,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29795,"numValue":0.84,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":29796,"numValue":1.74,"references":[],"strValue":null,"type":"M"},{"datasets":[],"id":29797,"numValue":2.21,"references":[],... | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:17489 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,489 | train | mutant | 321 | 341 | 356 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66E | L66E | 1 | 1 | 0 | 0 | 66 | L | E | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,657 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.00959 | 0.124138 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159996,"numValue":-0.00958985195203689,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159997,"numValue":0.12413760445845,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17491 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,491 | train | mutant | 322 | 341 | 357 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66A | L66A | 1 | 1 | 0 | 0 | 66 | L | A | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 6,637 | ProTherm | 7 | CD | Thermal | sodium cacodylate-HCl | 100 mM | 70 | NaCl | 2 M | 1C9O_A:L66A | null | null | 2.13 | 0.07 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 58 | ARTICLE | Electrostatic stabilization of a thermophilic cold shock protein. | 2,001 | 10.1006/jmbi.2001.5050 | 11800561 | J Mol Biol;313;343-57 | 2 | Perl D|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"100 mM","ty... | [{"datasets":[],"id":23676,"numValue":2.13,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":23677,"numValue":0.07,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23678,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:17492 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,492 | train | mutant | 322 | 341 | 357 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66A | L66A | 1 | 1 | 0 | 0 | 66 | L | A | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 6,667 | ProTherm | 7 | CD | Thermal | Sodium cacodylate-HCl | 0.1 M | 70 | NaCl | 2 M | 1C9O_A:L66A | null | null | 2.13 | 0.07 | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|DDG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 392 | ARTICLE | Two exposed amino acid residues confer thermostability on a cold shock protein. | 2,000 | 10.1038/75151 | 10802734 | Nat Struct Biol;7;380-3 | 4 | Perl D|Mueller U|Heinemann U|Schmid F X | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":70.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium cacodylate-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","typ... | [{"datasets":[],"id":23762,"numValue":2.13,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":23763,"numValue":0.07,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":23764,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:17494 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,494 | train | mutant | 322 | 341 | 357 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66A | L66A | 1 | 1 | 0 | 0 | 66 | L | A | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,654 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.055177 | 0.064816 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159990,"numValue":-0.0551769186086939,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159991,"numValue":0.0648160891218884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17495 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,495 | train | mutant | 4,901,819 | 341 | 4,908,405 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66C | L66C | 1 | 1 | 0 | 0 | 66 | L | C | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,655 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.067164 | 0.084058 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159992,"numValue":-0.0671639371631561,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159993,"numValue":0.0840576190587596,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17496 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,496 | train | mutant | 4,901,820 | 341 | 4,908,406 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66D | L66D | 1 | 1 | 0 | 0 | 66 | L | D | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,656 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.101102 | 0.179646 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159994,"numValue":-0.101102457602142,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159995,"numValue":0.179645882149922,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17497 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,497 | train | mutant | 4,901,821 | 341 | 4,908,407 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66F | L66F | 1 | 1 | 0 | 0 | 66 | L | F | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,658 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.032594 | 0.086306 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12159998,"numValue":0.0325935226593365,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12159999,"numValue":0.0863060593751937,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17498 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,498 | train | mutant | 4,901,822 | 341 | 4,908,408 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66G | L66G | 1 | 1 | 0 | 0 | 66 | L | G | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,659 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.005263 | 0.080107 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160000,"numValue":0.0052626224273818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160001,"numValue":0.080107273442567,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17499 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,499 | train | mutant | 4,901,823 | 341 | 4,908,409 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66H | L66H | 1 | 1 | 0 | 0 | 66 | L | H | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,660 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.214385 | 0.108951 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160002,"numValue":-0.214384584388269,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160003,"numValue":0.108950925694648,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17500 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,500 | train | mutant | 4,901,824 | 341 | 4,908,410 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66I | L66I | 1 | 1 | 0 | 0 | 66 | L | I | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,661 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.044131 | 0.083385 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160004,"numValue":-0.0441306278974683,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160005,"numValue":0.0833847052291174,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17502 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,502 | train | mutant | 4,901,826 | 341 | 4,908,412 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66M | L66M | 1 | 1 | 0 | 0 | 66 | L | M | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,663 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.017612 | 0.056838 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160008,"numValue":-0.0176124169365138,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160009,"numValue":0.0568378515653367,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17504 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,504 | train | mutant | 4,901,828 | 341 | 4,908,414 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66P | L66P | 1 | 1 | 0 | 0 | 66 | L | P | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,665 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.022425 | 0.043295 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160012,"numValue":-0.0224245332763973,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160013,"numValue":0.0432947968400786,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17505 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,505 | train | mutant | 4,901,829 | 341 | 4,908,415 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66Q | L66Q | 1 | 1 | 0 | 0 | 66 | L | Q | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,666 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.020676 | 0.056524 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160014,"numValue":0.0206764511026701,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160015,"numValue":0.0565238191837919,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17506 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,506 | train | mutant | 4,901,830 | 341 | 4,908,416 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66R | L66R | 1 | 1 | 0 | 0 | 66 | L | R | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,667 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01837 | 0.04241 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160016,"numValue":-0.0183699784889124,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160017,"numValue":0.042410275558969,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17507 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,507 | train | mutant | 4,901,831 | 341 | 4,908,417 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66S | L66S | 1 | 1 | 0 | 0 | 66 | L | S | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,668 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.016079 | 0.040496 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160018,"numValue":-0.0160789179255162,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160019,"numValue":0.0404962826630973,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17508 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,508 | train | mutant | 4,901,832 | 341 | 4,908,418 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66T | L66T | 1 | 1 | 0 | 0 | 66 | L | T | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,669 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.023296 | 0.056549 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160020,"numValue":-0.023295906893006,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160021,"numValue":0.0565490119584218,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17509 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,509 | train | mutant | 4,901,833 | 341 | 4,908,419 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66V | L66V | 1 | 1 | 0 | 0 | 66 | L | V | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,670 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.024568 | 0.062882 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160022,"numValue":0.0245679938190209,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160023,"numValue":0.0628821731870682,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17510 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,510 | train | mutant | 4,901,834 | 341 | 4,908,420 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66W | L66W | 1 | 1 | 0 | 0 | 66 | L | W | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,671 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.004475 | 0.049608 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160024,"numValue":0.00447542231659515,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160025,"numValue":0.0496083077045138,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17511 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,511 | train | mutant | 4,901,835 | 341 | 4,908,421 | 66 | 66 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | 35 | Cold shock protein CspB | Bacillus caldolyticus | 1 | P41016 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | L66Y | L66Y | 1 | 1 | 0 | 0 | 66 | L | Y | 5 | CONSERVATION | 1C9O | 231 | null | 66 | A|B | L | false | false | 115.415856 | 23.579444 | 5,083,672 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.053942 | 0.120792 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12160026,"numValue":-0.0539421762662477,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12160027,"numValue":0.120791648324907,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":20808,"numValue":5.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:17512 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 17,512 | train | sequence | 358 | 358 | -1 | 67 | -1 | 36 | Cold shock protein CspB | Bacillus subtilis (strain 168) | 1 | 36|1483 | Cold shock protein CspB|1CSQ | Bacillus subtilis (strain 168) | 1 | P32081 | IPR012156|IPR050181|IPR011129|IPR019844|IPR002059|IPR012340 | 1CSQ | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 17,990 | ProTherm | 7.5 | DSC | Thermal | HEPES | 50 mM | null | 52.8 | null | null | null | 26.29 | null | 49.95 | null | null | null | null | null | null | null | null | null | Unknown | TM|DH|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 1051 | ARTICLE | Effect of pH and phosphate ions on self-association properties of the major cold-shock protein from Bacillus subtilis. | 1,994 | 10.1002/pro.5560031127 | 7703860 | Protein Sci;3;2144-7 | 2 | Makhatadze G I|Marahiel M A | [{"numValue":7.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"HEPES","type":"BUFFER"},{"numValue":null,"strValue":"50 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":66514,"numValue":52.8,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":66515,"numValue":26.29,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":66516,"numValue":49.95,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":66517,"numValue":null,"references"... |
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