row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5330 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,330 | train | mutant | 4,890,238 | 69 | 4,896,819 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E37Y | E37Y | 1 | 1 | 0 | 0 | 37 | E | Y | 3 | CONSERVATION | 1TIN | 58 | null | 37 | A | E | false | false | 118.631003 | 0.664 | 5,042,756 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.362849 | 0.113345 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078194,"numValue":-0.362849100375476,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078195,"numValue":0.113345236288182,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7555,"numValue":3.0,"position":37,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5331 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,331 | train | mutant | 7,290 | 69 | 7,960 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38C|W54C | E38C|W54C | 2 | 2 | 0 | 0 | 38 | E | C | 4 | CONSERVATION | 1TIN | 58 | null | 38|54 | A | S|E | true | true | 69.99367 | 0.57725 | 15,647 | ProTherm | 2.5 | DSC | Thermal | dialyzate | null | 1TIN_A:E38C 1TIN_A:W54C | 73.6 | 2.7 | null | null | 43 | 0.33 | null | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DH|DCP|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|_PDB_CHAIN_MUTATION | 10 | ARTICLE | Disulfide bond effects on protein stability: designed variants of Cucurbita maxima trypsin inhibitor-V. | 2,001 | 10.1110/ps.26801 | 11266603 | Protein Sci;10;149-60 | 6 | Zavodszky M|Zolkiewski M|Wen L|Chen C W|Huang J K|Krishnamoorthi R | [{"numValue":2.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"dialyzate","type":"BUFFER"},{"numValue":null,"strValue":"1TIN_A:E38C 1TIN_A:W54C","type":"_PDB_CHAIN_MUTATION"}] | [{"datasets":[],"id":57424,"numValue":73.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57425,"numValue":2.7,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57426,"numValue":43.0,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57427,"numValue":0.33,"references":[],... | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":7572,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||
fireprotdb:5332 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,332 | train | mutant | 4,889,612 | 69 | 4,896,193 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38A | E38A | 1 | 1 | 0 | 0 | 38 | E | A | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,123 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.235417 | 0.045147 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076928,"numValue":-0.235416714261479,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076929,"numValue":0.0451474708529218,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5333 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,333 | train | mutant | 4,889,613 | 69 | 4,896,194 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38C | E38C | 1 | 1 | 0 | 0 | 38 | E | C | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,124 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.218744 | 0.062338 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076930,"numValue":-0.218743531515795,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076931,"numValue":0.0623378241954813,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5334 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,334 | train | mutant | 4,889,614 | 69 | 4,896,195 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38D | E38D | 1 | 1 | 0 | 0 | 38 | E | D | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,125 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.288068 | 0.077428 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076932,"numValue":-0.288067819098386,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076933,"numValue":0.0774276015842273,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5335 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,335 | train | mutant | 4,890,207 | 69 | 4,896,788 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38F | E38F | 1 | 1 | 0 | 0 | 38 | E | F | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,725 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.601414 | 0.087782 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078132,"numValue":-0.601413696136862,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078133,"numValue":0.0877817196836238,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5336 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,336 | train | mutant | 4,890,208 | 69 | 4,896,789 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38G | E38G | 1 | 1 | 0 | 0 | 38 | E | G | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,726 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.706717 | 0.059021 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078134,"numValue":-0.70671725532688,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078135,"numValue":0.0590206503860378,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5337 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,337 | train | mutant | 4,890,209 | 69 | 4,896,790 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38H | E38H | 1 | 1 | 0 | 0 | 38 | E | H | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,727 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.21659 | 0.074843 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078136,"numValue":-0.216589973555771,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078137,"numValue":0.0748429721612108,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5338 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,338 | train | mutant | 4,890,210 | 69 | 4,896,791 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38I | E38I | 1 | 1 | 0 | 0 | 38 | E | I | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,728 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.035699 | 0.066816 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078138,"numValue":0.0356992020110051,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078139,"numValue":0.0668157618767644,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5339 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,339 | train | mutant | 4,890,211 | 69 | 4,896,792 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38K | E38K | 1 | 1 | 0 | 0 | 38 | E | K | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,729 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.214238 | 0.067486 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078140,"numValue":-0.214238306616846,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078141,"numValue":0.0674858686467709,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5340 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,340 | train | mutant | 4,890,212 | 69 | 4,896,793 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38L | E38L | 1 | 1 | 0 | 0 | 38 | E | L | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,730 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.222625 | 0.040481 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078142,"numValue":-0.222624740121528,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078143,"numValue":0.0404814465997531,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5342 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,342 | train | mutant | 4,890,214 | 69 | 4,896,795 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38N | E38N | 1 | 1 | 0 | 0 | 38 | E | N | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,732 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.594547 | 0.122404 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078146,"numValue":-0.594546637943576,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078147,"numValue":0.122404448604957,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5343 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,343 | train | mutant | 4,890,215 | 69 | 4,896,796 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38P | E38P | 1 | 1 | 0 | 0 | 38 | E | P | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,733 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.41338 | 0.062605 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078148,"numValue":-0.413379575447762,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078149,"numValue":0.0626054602492674,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5344 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,344 | train | mutant | 4,890,216 | 69 | 4,896,797 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38Q | E38Q | 1 | 1 | 0 | 0 | 38 | E | Q | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,734 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.057991 | 0.060211 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078150,"numValue":-0.0579905106860725,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078151,"numValue":0.0602110856208392,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5345 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,345 | train | mutant | 4,890,217 | 69 | 4,896,798 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38R | E38R | 1 | 1 | 0 | 0 | 38 | E | R | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,735 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.324909 | 0.04055 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078152,"numValue":-0.324909071689854,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078153,"numValue":0.0405502179455626,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5346 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,346 | train | mutant | 4,890,218 | 69 | 4,896,799 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38S | E38S | 1 | 1 | 0 | 0 | 38 | E | S | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,736 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.332996 | 0.038553 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078154,"numValue":-0.332996182500255,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078155,"numValue":0.0385529969395069,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5347 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,347 | train | mutant | 4,890,219 | 69 | 4,896,800 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38T | E38T | 1 | 1 | 0 | 0 | 38 | E | T | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,737 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.275105 | 0.049034 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078156,"numValue":-0.275104906239127,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078157,"numValue":0.0490338076202338,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5348 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,348 | train | mutant | 4,890,220 | 69 | 4,896,801 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38V | E38V | 1 | 1 | 0 | 0 | 38 | E | V | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,738 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.084469 | 0.04274 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078158,"numValue":-0.0844691882099258,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078159,"numValue":0.0427395110946962,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5349 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,349 | train | mutant | 4,890,221 | 69 | 4,896,802 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38W | E38W | 1 | 1 | 0 | 0 | 38 | E | W | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,739 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.235934 | 0.045175 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078160,"numValue":-0.235933578968015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078161,"numValue":0.0451749919867302,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5350 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,350 | train | mutant | 4,890,222 | 69 | 4,896,803 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | E38Y | E38Y | 1 | 1 | 0 | 0 | 38 | E | Y | 4 | CONSERVATION | 1TIN | 58 | null | 38 | A | S | false | false | 123.491209 | 0.828667 | 5,042,740 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.32838 | 0.061121 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078162,"numValue":-0.328380297272491,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078163,"numValue":0.0611206415494956,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7556,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5351 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,351 | train | mutant | 4,889,615 | 69 | 4,896,196 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delG39 | delG39 | 1 | 0 | 1 | 0 | 39 | G | - | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,126 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.031356 | 0.152285 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076934,"numValue":-1.03135618985958,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076935,"numValue":0.152285436417243,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5352 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,352 | train | mutant | 4,889,616 | 69 | 4,896,197 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39A | G39A | 1 | 1 | 0 | 0 | 39 | G | A | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,127 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.589855 | 0.063759 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076936,"numValue":-0.589855179808329,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076937,"numValue":0.0637592516207143,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5353 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,353 | train | mutant | 4,889,617 | 69 | 4,896,198 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39C | G39C | 1 | 1 | 0 | 0 | 39 | G | C | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,128 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.689914 | 0.091119 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076938,"numValue":-0.689913799283534,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076939,"numValue":0.0911186144232105,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5354 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,354 | train | mutant | 4,889,618 | 69 | 4,896,199 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39D | G39D | 1 | 1 | 0 | 0 | 39 | G | D | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,129 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.357821 | 0.069327 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076940,"numValue":-0.357821252834183,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076941,"numValue":0.069326527779491,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5356 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,356 | train | mutant | 4,889,620 | 69 | 4,896,201 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39F | G39F | 1 | 1 | 0 | 0 | 39 | G | F | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,131 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.63396 | 0.077473 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076944,"numValue":-0.633960248357369,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076945,"numValue":0.0774731072706617,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5358 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,358 | train | mutant | 4,890,194 | 69 | 4,896,775 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39I | G39I | 1 | 1 | 0 | 0 | 39 | G | I | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,712 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.700649 | 0.105168 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078106,"numValue":-0.700649290662479,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078107,"numValue":0.105168247698524,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5359 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,359 | train | mutant | 4,890,195 | 69 | 4,896,776 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39K | G39K | 1 | 1 | 0 | 0 | 39 | G | K | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,713 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.395316 | 0.095178 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078108,"numValue":-0.395315671268897,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078109,"numValue":0.0951779591680103,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5361 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,361 | train | mutant | 4,890,197 | 69 | 4,896,778 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39M | G39M | 1 | 1 | 0 | 0 | 39 | G | M | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,715 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.899133 | 0.111183 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078112,"numValue":-0.899132859275701,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078113,"numValue":0.111182501617964,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5362 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,362 | train | mutant | 4,890,198 | 69 | 4,896,779 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39N | G39N | 1 | 1 | 0 | 0 | 39 | G | N | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,716 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.194331 | 0.073096 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078114,"numValue":-0.19433060343089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078115,"numValue":0.0730959064756984,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5363 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,363 | train | mutant | 4,890,199 | 69 | 4,896,780 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39P | G39P | 1 | 1 | 0 | 0 | 39 | G | P | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,717 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.95717 | 0.119221 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078116,"numValue":-0.957170330426677,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078117,"numValue":0.119220939877237,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5364 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,364 | train | mutant | 4,890,200 | 69 | 4,896,781 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39Q | G39Q | 1 | 1 | 0 | 0 | 39 | G | Q | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,718 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.406953 | 0.091539 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078118,"numValue":-0.40695344918254,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078119,"numValue":0.091539033704958,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5365 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,365 | train | mutant | 4,890,201 | 69 | 4,896,782 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39R | G39R | 1 | 1 | 0 | 0 | 39 | G | R | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,719 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.724343 | 0.057145 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078120,"numValue":-0.724342836642344,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078121,"numValue":0.0571451737352273,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5366 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,366 | train | mutant | 4,890,202 | 69 | 4,896,783 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39S | G39S | 1 | 1 | 0 | 0 | 39 | G | S | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,720 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.556669 | 0.058609 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078122,"numValue":-0.556669496713109,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078123,"numValue":0.0586094797886822,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5367 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,367 | train | mutant | 4,890,203 | 69 | 4,896,784 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39T | G39T | 1 | 1 | 0 | 0 | 39 | G | T | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,721 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.741054 | 0.106788 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078124,"numValue":-0.741054435615998,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078125,"numValue":0.106788296918817,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5368 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,368 | train | mutant | 4,890,204 | 69 | 4,896,785 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39V | G39V | 1 | 1 | 0 | 0 | 39 | G | V | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,722 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.84971 | 0.060523 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078126,"numValue":-0.849710013123874,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078127,"numValue":0.0605226529254872,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5369 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,369 | train | mutant | 4,890,205 | 69 | 4,896,786 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39W | G39W | 1 | 1 | 0 | 0 | 39 | G | W | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,723 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.023664 | 0.143775 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078128,"numValue":-1.02366395648755,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078129,"numValue":0.143774937389443,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5370 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,370 | train | mutant | 4,890,206 | 69 | 4,896,787 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G39Y | G39Y | 1 | 1 | 0 | 0 | 39 | G | Y | 5 | CONSERVATION | 1TIN | 58 | null | 39 | A | L | false | false | 40.509033 | 0.501429 | 5,042,724 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.794753 | 0.143219 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078130,"numValue":-0.794753304834508,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078131,"numValue":0.143219206616202,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7557,"numValue":5.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5371 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,371 | train | mutant | 4,889,621 | 69 | 4,896,202 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delT40 | delT40 | 1 | 0 | 1 | 0 | 40 | T | - | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,132 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.676673 | 0.07404 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076946,"numValue":-0.676672886086035,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076947,"numValue":0.0740398300837102,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5373 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,373 | train | mutant | 4,889,623 | 69 | 4,896,204 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40C | T40C | 1 | 1 | 0 | 0 | 40 | T | C | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,134 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.288528 | 0.059704 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076950,"numValue":-0.288528094092056,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076951,"numValue":0.0597040184019526,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5374 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,374 | train | mutant | 4,889,624 | 69 | 4,896,205 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40D | T40D | 1 | 1 | 0 | 0 | 40 | T | D | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,135 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.389137 | 0.105009 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076952,"numValue":-0.389137496114417,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076953,"numValue":0.105009364657316,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5375 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,375 | train | mutant | 4,889,625 | 69 | 4,896,206 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40E | T40E | 1 | 1 | 0 | 0 | 40 | T | E | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,136 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.316194 | 0.077317 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076954,"numValue":-0.31619362613438,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076955,"numValue":0.0773170852038081,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5377 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,377 | train | mutant | 4,889,627 | 69 | 4,896,208 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40G | T40G | 1 | 1 | 0 | 0 | 40 | T | G | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,138 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.591833 | 0.070566 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076958,"numValue":-0.591833390629443,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076959,"numValue":0.0705655006138009,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5378 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,378 | train | mutant | 4,889,628 | 69 | 4,896,209 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40H | T40H | 1 | 1 | 0 | 0 | 40 | T | H | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,139 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.165682 | 0.07136 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076960,"numValue":-0.165682263720299,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076961,"numValue":0.0713596369198265,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5379 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,379 | train | mutant | 4,889,629 | 69 | 4,896,210 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40I | T40I | 1 | 1 | 0 | 0 | 40 | T | I | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,140 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.316303 | 0.078438 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076962,"numValue":-0.316302757011495,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076963,"numValue":0.0784375435249902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5380 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,380 | train | mutant | 4,889,630 | 69 | 4,896,211 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40K | T40K | 1 | 1 | 0 | 0 | 40 | T | K | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,141 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.257336 | 0.067095 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076964,"numValue":-0.257336276205928,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076965,"numValue":0.0670948688182935,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5381 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,381 | train | mutant | 4,889,631 | 69 | 4,896,212 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40L | T40L | 1 | 1 | 0 | 0 | 40 | T | L | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,142 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.379817 | 0.03892 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076966,"numValue":-0.379816747557103,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076967,"numValue":0.0389203172569729,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5382 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,382 | train | mutant | 4,889,632 | 69 | 4,896,213 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40M | T40M | 1 | 1 | 0 | 0 | 40 | T | M | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,143 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.285236 | 0.056788 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076968,"numValue":-0.28523635416469,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076969,"numValue":0.0567875789312123,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5383 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,383 | train | mutant | 4,889,633 | 69 | 4,896,214 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40N | T40N | 1 | 1 | 0 | 0 | 40 | T | N | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,144 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.644035 | 0.155239 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076970,"numValue":-0.644035196537814,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076971,"numValue":0.15523934745461,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5384 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,384 | train | mutant | 4,889,634 | 69 | 4,896,215 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40P | T40P | 1 | 1 | 0 | 0 | 40 | T | P | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,145 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.900853 | 0.111351 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076972,"numValue":-0.900853321498424,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076973,"numValue":0.111351011208102,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5385 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,385 | train | mutant | 4,889,635 | 69 | 4,896,216 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40Q | T40Q | 1 | 1 | 0 | 0 | 40 | T | Q | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,146 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11304 | 0.059556 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076974,"numValue":-0.113039525883864,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076975,"numValue":0.0595559674774836,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5386 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,386 | train | mutant | 4,889,636 | 69 | 4,896,217 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40R | T40R | 1 | 1 | 0 | 0 | 40 | T | R | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,147 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.444924 | 0.041262 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076976,"numValue":-0.444923796998902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076977,"numValue":0.0412617098791907,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5387 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,387 | train | mutant | 4,889,637 | 69 | 4,896,218 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40S | T40S | 1 | 1 | 0 | 0 | 40 | T | S | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,148 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.170981 | 0.039781 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076978,"numValue":-0.170980644276832,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076979,"numValue":0.0397809217344847,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5388 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,388 | train | mutant | 4,890,190 | 69 | 4,896,771 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40V | T40V | 1 | 1 | 0 | 0 | 40 | T | V | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,708 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.294849 | 0.050179 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078098,"numValue":-0.294848778157789,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078099,"numValue":0.050179483900901,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5389 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,389 | train | mutant | 4,890,191 | 69 | 4,896,772 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T40W | T40W | 1 | 1 | 0 | 0 | 40 | T | W | 6 | CONSERVATION | 1TIN | 58 | null | 40 | A | S | false | false | 83.591809 | 0.725 | 5,042,709 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.635775 | 0.056442 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078100,"numValue":-0.635775347653166,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078101,"numValue":0.0564424176698332,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7558,"numValue":6.0,"position":40,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5391 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,391 | train | mutant | 4,889,638 | 69 | 4,896,219 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delP41 | delP41 | 1 | 0 | 1 | 0 | 41 | P | - | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,149 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.573276 | 0.071256 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076980,"numValue":-0.573276283261505,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076981,"numValue":0.0712558681204326,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5393 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,393 | train | mutant | 4,889,640 | 69 | 4,896,221 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41C | P41C | 1 | 1 | 0 | 0 | 41 | P | C | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,151 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.343655 | 0.109778 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076984,"numValue":-0.343654931391005,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076985,"numValue":0.109778285022733,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5394 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,394 | train | mutant | 4,889,641 | 69 | 4,896,222 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41D | P41D | 1 | 1 | 0 | 0 | 41 | P | D | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,152 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.094728 | 0.084027 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076986,"numValue":-0.0947280304652456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076987,"numValue":0.0840269247592058,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5395 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,395 | train | mutant | 4,889,642 | 69 | 4,896,223 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41E | P41E | 1 | 1 | 0 | 0 | 41 | P | E | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,153 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.036609 | 0.051006 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076988,"numValue":-0.036608775933211,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076989,"numValue":0.0510058376571285,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5396 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,396 | train | mutant | 4,889,643 | 69 | 4,896,224 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41F | P41F | 1 | 1 | 0 | 0 | 41 | P | F | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,154 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.233792 | 0.077824 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076990,"numValue":-0.233791806782848,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076991,"numValue":0.0778244043323864,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5397 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,397 | train | mutant | 4,889,644 | 69 | 4,896,225 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41G | P41G | 1 | 1 | 0 | 0 | 41 | P | G | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,155 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.304844 | 0.043361 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076992,"numValue":-0.304843565075654,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076993,"numValue":0.0433610532748701,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5398 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,398 | train | mutant | 4,889,645 | 69 | 4,896,226 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41H | P41H | 1 | 1 | 0 | 0 | 41 | P | H | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,156 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.162556 | 0.090895 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076994,"numValue":-0.16255606444742,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076995,"numValue":0.0908947746686657,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5399 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,399 | train | mutant | 4,889,646 | 69 | 4,896,227 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41I | P41I | 1 | 1 | 0 | 0 | 41 | P | I | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,157 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.077681 | 0.077321 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076996,"numValue":-0.0776812116662556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076997,"numValue":0.0773214036556643,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5400 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,400 | train | mutant | 4,889,647 | 69 | 4,896,228 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41K | P41K | 1 | 1 | 0 | 0 | 41 | P | K | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,158 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.020836 | 0.055534 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12076998,"numValue":-0.0208356305285502,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12076999,"numValue":0.0555344631670735,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5402 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,402 | train | mutant | 4,889,649 | 69 | 4,896,230 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41M | P41M | 1 | 1 | 0 | 0 | 41 | P | M | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,160 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11529 | 0.054978 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077002,"numValue":-0.115290069075158,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077003,"numValue":0.054978480484141,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5403 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,403 | train | mutant | 4,889,650 | 69 | 4,896,231 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41N | P41N | 1 | 1 | 0 | 0 | 41 | P | N | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,161 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.214687 | 0.079091 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077004,"numValue":-0.214686615900164,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077005,"numValue":0.0790906823779119,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5404 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,404 | train | mutant | 4,890,183 | 69 | 4,896,764 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41Q | P41Q | 1 | 1 | 0 | 0 | 41 | P | Q | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,701 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.017328 | 0.059109 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078084,"numValue":-0.0173277880728821,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078085,"numValue":0.0591088997490736,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5405 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,405 | train | mutant | 4,890,184 | 69 | 4,896,765 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41R | P41R | 1 | 1 | 0 | 0 | 41 | P | R | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,702 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.067644 | 0.044881 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078086,"numValue":-0.0676444997782876,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078087,"numValue":0.0448812652863131,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5406 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,406 | train | mutant | 4,890,185 | 69 | 4,896,766 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41S | P41S | 1 | 1 | 0 | 0 | 41 | P | S | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,703 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.090084 | 0.046973 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078088,"numValue":-0.0900840753004168,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078089,"numValue":0.0469733662783587,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5407 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,407 | train | mutant | 4,890,186 | 69 | 4,896,767 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41T | P41T | 1 | 1 | 0 | 0 | 41 | P | T | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,704 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.094241 | 0.056627 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078090,"numValue":-0.0942408551152214,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078091,"numValue":0.0566268695447399,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5408 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,408 | train | mutant | 4,890,187 | 69 | 4,896,768 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41V | P41V | 1 | 1 | 0 | 0 | 41 | P | V | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,705 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.015797 | 0.036057 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078092,"numValue":-0.0157974366963518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078093,"numValue":0.0360574085956997,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5409 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,409 | train | mutant | 4,890,188 | 69 | 4,896,769 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41W | P41W | 1 | 1 | 0 | 0 | 41 | P | W | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,706 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.400315 | 0.056343 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078094,"numValue":-0.400314639163402,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078095,"numValue":0.0563434171610305,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5410 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,410 | train | mutant | 4,890,189 | 69 | 4,896,770 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P41Y | P41Y | 1 | 1 | 0 | 0 | 41 | P | Y | 2 | CONSERVATION | 1TIN | 58 | null | 41 | A | L | false | false | 120.358216 | 1.075714 | 5,042,707 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.3821 | 0.089342 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078096,"numValue":-0.382099679137318,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078097,"numValue":0.0893419853360328,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7559,"numValue":2.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5411 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,411 | train | mutant | 7,291 | 69 | 7,961 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42C|R52C | V42C|R52C | 2 | 2 | 0 | 0 | 42 | V | C | 7 | CONSERVATION | 1TIN | 58 | null | 42|52 | A | L|E | true | true | 54.509527 | 0.603229 | 15,648 | ProTherm | 2.5 | DSC | Thermal | dialyzate | null | 1TIN_A:V42C 1TIN_A:R52C | 87.8 | 16.9 | null | null | 47 | 0.15 | null | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DH|DCP|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|_PDB_CHAIN_MUTATION | 10 | ARTICLE | Disulfide bond effects on protein stability: designed variants of Cucurbita maxima trypsin inhibitor-V. | 2,001 | 10.1110/ps.26801 | 11266603 | Protein Sci;10;149-60 | 6 | Zavodszky M|Zolkiewski M|Wen L|Chen C W|Huang J K|Krishnamoorthi R | [{"numValue":2.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"dialyzate","type":"BUFFER"},{"numValue":null,"strValue":"1TIN_A:V42C 1TIN_A:R52C","type":"_PDB_CHAIN_MUTATION"}] | [{"datasets":[],"id":57429,"numValue":87.8,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":57430,"numValue":16.9,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":57431,"numValue":47.0,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":57432,"numValue":0.15,"references":[]... | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"},{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||
fireprotdb:5413 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,413 | train | mutant | 4,889,652 | 69 | 4,896,233 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42A | V42A | 1 | 1 | 0 | 0 | 42 | V | A | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,163 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.05175 | 0.063488 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077008,"numValue":-0.051750347753907,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077009,"numValue":0.0634881338151191,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5414 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,414 | train | mutant | 4,889,653 | 69 | 4,896,234 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42C | V42C | 1 | 1 | 0 | 0 | 42 | V | C | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,164 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.272069 | 0.12794 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077010,"numValue":-0.272069124551987,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077011,"numValue":0.12793971423935,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5415 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,415 | train | mutant | 4,889,654 | 69 | 4,896,235 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42D | V42D | 1 | 1 | 0 | 0 | 42 | V | D | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,165 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.156178 | 0.099222 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077012,"numValue":-0.156177980959098,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077013,"numValue":0.0992221893313134,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5416 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,416 | train | mutant | 4,889,655 | 69 | 4,896,236 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42E | V42E | 1 | 1 | 0 | 0 | 42 | V | E | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,166 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.238536 | 0.07803 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077014,"numValue":-0.238535896050092,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077015,"numValue":0.0780296207633015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5417 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,417 | train | mutant | 4,889,656 | 69 | 4,896,237 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42F | V42F | 1 | 1 | 0 | 0 | 42 | V | F | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,167 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.533073 | 0.107015 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077016,"numValue":-0.533073385803249,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077017,"numValue":0.107014835705772,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5418 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,418 | train | mutant | 4,889,657 | 69 | 4,896,238 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42G | V42G | 1 | 1 | 0 | 0 | 42 | V | G | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,168 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.614464 | 0.077687 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077018,"numValue":-0.614464057646208,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077019,"numValue":0.0776873654601506,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5419 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,419 | train | mutant | 4,889,658 | 69 | 4,896,239 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42H | V42H | 1 | 1 | 0 | 0 | 42 | V | H | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,169 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.07299 | 0.097646 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077020,"numValue":-0.0729897535310089,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077021,"numValue":0.0976456845005704,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5420 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,420 | train | mutant | 4,889,659 | 69 | 4,896,240 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42I | V42I | 1 | 1 | 0 | 0 | 42 | V | I | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,170 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.535527 | 0.179109 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077022,"numValue":-0.535527076167277,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077023,"numValue":0.179108870347614,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5421 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,421 | train | mutant | 4,889,660 | 69 | 4,896,241 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42K | V42K | 1 | 1 | 0 | 0 | 42 | V | K | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,171 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.469526 | 0.138805 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077024,"numValue":-0.469525567384768,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077025,"numValue":0.138804849141726,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5422 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,422 | train | mutant | 4,889,661 | 69 | 4,896,242 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42L | V42L | 1 | 1 | 0 | 0 | 42 | V | L | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,172 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.38592 | 0.064346 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077026,"numValue":-0.38592024948157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077027,"numValue":0.0643455174472882,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5423 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,423 | train | mutant | 4,889,662 | 69 | 4,896,243 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42M | V42M | 1 | 1 | 0 | 0 | 42 | V | M | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,173 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.305035 | 0.091718 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077028,"numValue":-0.305035376312265,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077029,"numValue":0.0917184293924831,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5424 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,424 | train | mutant | 4,889,663 | 69 | 4,896,244 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42N | V42N | 1 | 1 | 0 | 0 | 42 | V | N | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,174 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.430748 | 0.245334 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077030,"numValue":-0.430747849006796,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077031,"numValue":0.245333859013679,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5425 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,425 | train | mutant | 4,889,664 | 69 | 4,896,245 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42P | V42P | 1 | 1 | 0 | 0 | 42 | V | P | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,175 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.47266 | 0.107242 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077032,"numValue":-0.472659683819383,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077033,"numValue":0.107241554428221,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5426 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,426 | train | mutant | 4,889,665 | 69 | 4,896,246 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42Q | V42Q | 1 | 1 | 0 | 0 | 42 | V | Q | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,176 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.460209 | 0.152436 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077034,"numValue":-0.460209497150298,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077035,"numValue":0.15243595245798,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5427 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,427 | train | mutant | 4,889,666 | 69 | 4,896,247 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42R | V42R | 1 | 1 | 0 | 0 | 42 | V | R | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,177 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.496262 | 0.061237 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077036,"numValue":-0.496262272407027,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077037,"numValue":0.0612367089399049,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5428 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,428 | train | mutant | 4,889,667 | 69 | 4,896,248 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42S | V42S | 1 | 1 | 0 | 0 | 42 | V | S | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,178 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.23367 | 0.075809 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077038,"numValue":-0.233669990453405,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077039,"numValue":0.0758092977382264,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5429 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,429 | train | mutant | 4,889,668 | 69 | 4,896,249 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42T | V42T | 1 | 1 | 0 | 0 | 42 | V | T | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,179 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.024091 | 0.086362 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077040,"numValue":0.0240906636151381,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077041,"numValue":0.0863620106423586,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5430 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,430 | train | mutant | 4,890,181 | 69 | 4,896,762 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42W | V42W | 1 | 1 | 0 | 0 | 42 | V | W | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,699 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.504621 | 0.1082 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078080,"numValue":-0.504620815910138,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078081,"numValue":0.10819998083705,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5431 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,431 | train | mutant | 4,890,182 | 69 | 4,896,763 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V42Y | V42Y | 1 | 1 | 0 | 0 | 42 | V | Y | 7 | CONSERVATION | 1TIN | 58 | null | 42 | A | L | true | true | 55.954624 | 0.858125 | 5,042,700 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.341929 | 0.09651 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12078082,"numValue":-0.341929350003478,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12078083,"numValue":0.0965095717914097,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7560,"numValue":7.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5432 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,432 | train | mutant | 67 | 69 | 75 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T43A | T43A | 1 | 1 | 0 | 0 | 43 | T | A | 7 | CONSERVATION | 1TIN | 58 | null | 43 | A | S | false | true | 105.758412 | 1.306429 | 86 | ProTherm | 2.5 | DSC | Thermal | dialyzate | null | 1TIN_A:T43A | 71.7 | 0.8 | null | null | 58 | 0.34 | null | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DH|DCP|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|_PDB_CHAIN_MUTATION | 10 | ARTICLE | Disulfide bond effects on protein stability: designed variants of Cucurbita maxima trypsin inhibitor-V. | 2,001 | 10.1110/ps.26801 | 11266603 | Protein Sci;10;149-60 | 6 | Zavodszky M|Zolkiewski M|Wen L|Chen C W|Huang J K|Krishnamoorthi R | [{"numValue":2.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"dialyzate","type":"BUFFER"},{"numValue":null,"strValue":"1TIN_A:T43A","type":"_PDB_CHAIN_MUTATION"}] | [{"datasets":[],"id":297,"numValue":71.7,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":298,"numValue":0.8,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":299,"numValue":58.0,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":300... | [{"id":7561,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:5433 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,433 | train | mutant | 67 | 69 | 75 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T43A | T43A | 1 | 1 | 0 | 0 | 43 | T | A | 7 | CONSERVATION | 1TIN | 58 | null | 43 | A | S | false | true | 105.758412 | 1.306429 | 5,042,181 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.007986 | 0.041419 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077044,"numValue":0.00798643690150427,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077045,"numValue":0.0414190724654746,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7561,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5434 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,434 | train | mutant | 4,889,669 | 69 | 4,896,250 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delT43 | delT43 | 1 | 0 | 1 | 0 | 43 | T | - | 7 | CONSERVATION | 1TIN | 58 | null | 43 | A | S | false | true | 105.758412 | 1.306429 | 5,042,180 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.791249 | 0.069863 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077042,"numValue":-0.791248791185479,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077043,"numValue":0.0698628165226044,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7561,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5435 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,435 | train | mutant | 4,889,670 | 69 | 4,896,251 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T43C | T43C | 1 | 1 | 0 | 0 | 43 | T | C | 7 | CONSERVATION | 1TIN | 58 | null | 43 | A | S | false | true | 105.758412 | 1.306429 | 5,042,182 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.344464 | 0.060874 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077046,"numValue":-0.34446365146882,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077047,"numValue":0.0608739499872119,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7561,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5436 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,436 | train | mutant | 4,889,671 | 69 | 4,896,252 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T43D | T43D | 1 | 1 | 0 | 0 | 43 | T | D | 7 | CONSERVATION | 1TIN | 58 | null | 43 | A | S | false | true | 105.758412 | 1.306429 | 5,042,183 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.056958 | 0.06547 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077048,"numValue":-0.0569576809504719,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077049,"numValue":0.065469916355789,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7561,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5437 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,437 | train | mutant | 4,889,672 | 69 | 4,896,253 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T43E | T43E | 1 | 1 | 0 | 0 | 43 | T | E | 7 | CONSERVATION | 1TIN | 58 | null | 43 | A | S | false | true | 105.758412 | 1.306429 | 5,042,184 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.066628 | 0.051986 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077050,"numValue":0.0666283140758824,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077051,"numValue":0.0519861172317044,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7561,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5438 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,438 | train | mutant | 4,889,673 | 69 | 4,896,254 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T43F | T43F | 1 | 1 | 0 | 0 | 43 | T | F | 7 | CONSERVATION | 1TIN | 58 | null | 43 | A | S | false | true | 105.758412 | 1.306429 | 5,042,185 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.360149 | 0.055351 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077052,"numValue":-0.360148538513671,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077053,"numValue":0.0553506500631705,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7561,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5439 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,439 | train | mutant | 4,889,674 | 69 | 4,896,255 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | T43G | T43G | 1 | 1 | 0 | 0 | 43 | T | G | 7 | CONSERVATION | 1TIN | 58 | null | 43 | A | S | false | true | 105.758412 | 1.306429 | 5,042,186 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079752 | 0.048 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077054,"numValue":-0.0797517293957952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077055,"numValue":0.0480003481104041,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7561,"numValue":7.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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