row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5552 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,552 | train | mutant | 4,890,129 | 69 | 4,896,710 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | C48Y | C48Y | 1 | 1 | 0 | 0 | 48 | C | Y | 6 | CONSERVATION | 1TIN | 58 | null | 48 | A | T | true | false | 36.915846 | 0.544 | 5,042,647 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.228335 | 0.073199 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077976,"numValue":-0.228335442862577,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077977,"numValue":0.0731992794170055,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7566,"numValue":6.0,"position":48,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5553 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,553 | train | mutant | 4,889,719 | 69 | 4,896,300 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delN49 | delN49 | 1 | 0 | 1 | 0 | 49 | N | - | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,231 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.646349 | 0.066209 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077144,"numValue":-0.646348807119757,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077145,"numValue":0.0662093792619605,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5555 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,555 | train | mutant | 4,889,721 | 69 | 4,896,302 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49C | N49C | 1 | 1 | 0 | 0 | 49 | N | C | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,233 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.495637 | 0.081605 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077148,"numValue":-0.495636546726618,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077149,"numValue":0.0816049570227716,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5556 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,556 | train | mutant | 4,889,722 | 69 | 4,896,303 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49D | N49D | 1 | 1 | 0 | 0 | 49 | N | D | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,234 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.133889 | 0.07272 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077150,"numValue":0.1338891014132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077151,"numValue":0.0727195623932079,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5557 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,557 | train | mutant | 4,889,723 | 69 | 4,896,304 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49E | N49E | 1 | 1 | 0 | 0 | 49 | N | E | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,235 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.130784 | 0.05068 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077152,"numValue":-0.130783594722132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077153,"numValue":0.0506797585548889,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5558 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,558 | train | mutant | 4,889,724 | 69 | 4,896,305 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49F | N49F | 1 | 1 | 0 | 0 | 49 | N | F | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,236 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.762907 | 0.106499 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077154,"numValue":-0.762907331459918,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077155,"numValue":0.106499230547695,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5559 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,559 | train | mutant | 4,889,725 | 69 | 4,896,306 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49G | N49G | 1 | 1 | 0 | 0 | 49 | N | G | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,237 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.263064 | 0.035529 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077156,"numValue":-0.263063802915667,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077157,"numValue":0.0355294508659589,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5560 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,560 | train | mutant | 4,889,726 | 69 | 4,896,307 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49H | N49H | 1 | 1 | 0 | 0 | 49 | N | H | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,238 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.354484 | 0.076679 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077158,"numValue":-0.354484439065569,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077159,"numValue":0.0766792768549759,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5561 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,561 | train | mutant | 4,889,727 | 69 | 4,896,308 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49I | N49I | 1 | 1 | 0 | 0 | 49 | N | I | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,239 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.840148 | 0.151013 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077160,"numValue":-0.840148330940085,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077161,"numValue":0.151013292474613,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5562 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,562 | train | mutant | 4,889,728 | 69 | 4,896,309 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49K | N49K | 1 | 1 | 0 | 0 | 49 | N | K | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,240 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.625822 | 0.072595 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077162,"numValue":-0.62582203586667,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077163,"numValue":0.0725951010120032,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5563 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,563 | train | mutant | 4,889,729 | 69 | 4,896,310 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49L | N49L | 1 | 1 | 0 | 0 | 49 | N | L | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,241 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.73242 | 0.049735 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077164,"numValue":-0.732419691129586,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077165,"numValue":0.0497352771468457,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5564 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,564 | train | mutant | 4,889,730 | 69 | 4,896,311 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49M | N49M | 1 | 1 | 0 | 0 | 49 | N | M | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,242 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.789309 | 0.087349 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077166,"numValue":-0.789308636721348,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077167,"numValue":0.0873491547560308,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5565 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,565 | train | mutant | 4,890,104 | 69 | 4,896,685 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49P | N49P | 1 | 1 | 0 | 0 | 49 | N | P | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,622 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.485717 | 0.056119 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077926,"numValue":-0.485716523006513,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077927,"numValue":0.0561192625193712,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5566 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,566 | train | mutant | 4,890,105 | 69 | 4,896,686 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49Q | N49Q | 1 | 1 | 0 | 0 | 49 | N | Q | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,623 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.401153 | 0.060826 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077928,"numValue":-0.401152508791246,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077929,"numValue":0.0608256912877192,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5567 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,567 | train | mutant | 4,890,106 | 69 | 4,896,687 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49R | N49R | 1 | 1 | 0 | 0 | 49 | N | R | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,624 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.543663 | 0.038687 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077930,"numValue":-0.543662679593313,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077931,"numValue":0.0386867160018782,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5568 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,568 | train | mutant | 4,890,107 | 69 | 4,896,688 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49S | N49S | 1 | 1 | 0 | 0 | 49 | N | S | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,625 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.156101 | 0.038663 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077932,"numValue":-0.156100608696675,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077933,"numValue":0.0386634863296019,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5569 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,569 | train | mutant | 4,890,108 | 69 | 4,896,689 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49T | N49T | 1 | 1 | 0 | 0 | 49 | N | T | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,626 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.11955 | 0.047178 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077934,"numValue":-0.119550401766764,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077935,"numValue":0.0471782588253846,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5570 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,570 | train | mutant | 4,890,109 | 69 | 4,896,690 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49V | N49V | 1 | 1 | 0 | 0 | 49 | N | V | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,627 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.752168 | 0.057418 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077936,"numValue":-0.75216833133884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077937,"numValue":0.0574184867538493,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5571 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,571 | train | mutant | 4,890,110 | 69 | 4,896,691 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49W | N49W | 1 | 1 | 0 | 0 | 49 | N | W | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,628 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.689446 | 0.057059 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077938,"numValue":-0.689446326870104,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077939,"numValue":0.0570585977722858,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5572 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,572 | train | mutant | 4,890,111 | 69 | 4,896,692 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | N49Y | N49Y | 1 | 1 | 0 | 0 | 49 | N | Y | 5 | CONSERVATION | 1TIN | 58 | null | 49 | A | T | false | false | 68.211129 | 0.564286 | 5,042,629 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.604536 | 0.10469 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077940,"numValue":-0.604536116764367,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077941,"numValue":0.104689619284466,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7567,"numValue":5.0,"position":49,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5573 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,573 | train | mutant | 62 | 69 | 70 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50A | R50A | 1 | 1 | 0 | 0 | 50 | R | A | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 81 | ProTherm | 2.5 | DSC | Thermal | dialyzate | null | 1TIN_A:R50A | 62.6 | -8.3 | null | null | 31 | 0.13 | null | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DH|DCP|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|_PDB_CHAIN_MUTATION | 10 | ARTICLE | Disulfide bond effects on protein stability: designed variants of Cucurbita maxima trypsin inhibitor-V. | 2,001 | 10.1110/ps.26801 | 11266603 | Protein Sci;10;149-60 | 6 | Zavodszky M|Zolkiewski M|Wen L|Chen C W|Huang J K|Krishnamoorthi R | [{"numValue":2.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"dialyzate","type":"BUFFER"},{"numValue":null,"strValue":"1TIN_A:R50A","type":"_PDB_CHAIN_MUTATION"}] | [{"datasets":[],"id":272,"numValue":62.6,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":273,"numValue":-8.3,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":274,"numValue":31.0,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":27... | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:5574 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,574 | train | mutant | 62 | 69 | 70 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50A | R50A | 1 | 1 | 0 | 0 | 50 | R | A | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,244 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.01506 | 0.054252 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077170,"numValue":-0.0150597011709228,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077171,"numValue":0.0542515410883524,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5575 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,575 | train | mutant | 63 | 69 | 71 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50K | R50K | 1 | 1 | 0 | 0 | 50 | R | K | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 82 | ProTherm | 2.5 | DSC | Thermal | dialyzate | null | 1TIN_A:R50K | 59.2 | -11.7 | null | null | 35 | 0.23 | null | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DH|DCP|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|_PDB_CHAIN_MUTATION | 10 | ARTICLE | Disulfide bond effects on protein stability: designed variants of Cucurbita maxima trypsin inhibitor-V. | 2,001 | 10.1110/ps.26801 | 11266603 | Protein Sci;10;149-60 | 6 | Zavodszky M|Zolkiewski M|Wen L|Chen C W|Huang J K|Krishnamoorthi R | [{"numValue":2.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"dialyzate","type":"BUFFER"},{"numValue":null,"strValue":"1TIN_A:R50K","type":"_PDB_CHAIN_MUTATION"}] | [{"datasets":[],"id":277,"numValue":59.2,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":278,"numValue":-11.7,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":279,"numValue":35.0,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":2... | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:5576 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,576 | train | mutant | 63 | 69 | 71 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50K | R50K | 1 | 1 | 0 | 0 | 50 | R | K | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,252 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.009701 | 0.067565 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077186,"numValue":0.00970122215939176,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077187,"numValue":0.0675654990996437,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5577 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,577 | train | mutant | 4,889,731 | 69 | 4,896,312 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delR50 | delR50 | 1 | 0 | 1 | 0 | 50 | R | - | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,243 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.718358 | 0.10014 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077168,"numValue":-0.718358272079415,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077169,"numValue":0.100139770383003,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5578 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,578 | train | mutant | 4,889,732 | 69 | 4,896,313 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50C | R50C | 1 | 1 | 0 | 0 | 50 | R | C | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,245 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.14004 | 0.086558 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077172,"numValue":0.140040196275832,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077173,"numValue":0.0865579334050082,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5579 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,579 | train | mutant | 4,889,733 | 69 | 4,896,314 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50D | R50D | 1 | 1 | 0 | 0 | 50 | R | D | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,246 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.041397 | 0.107308 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077174,"numValue":0.0413968594287393,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077175,"numValue":0.107307770690016,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5580 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,580 | train | mutant | 4,889,734 | 69 | 4,896,315 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50E | R50E | 1 | 1 | 0 | 0 | 50 | R | E | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,247 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.182904 | 0.069461 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077176,"numValue":0.182904429658199,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077177,"numValue":0.0694606157096251,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5581 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,581 | train | mutant | 4,889,735 | 69 | 4,896,316 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50F | R50F | 1 | 1 | 0 | 0 | 50 | R | F | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,248 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.172654 | 0.102932 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077178,"numValue":-0.172654044371098,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077179,"numValue":0.102932459217739,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5582 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,582 | train | mutant | 4,889,736 | 69 | 4,896,317 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50G | R50G | 1 | 1 | 0 | 0 | 50 | R | G | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,249 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.069631 | 0.064413 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077180,"numValue":-0.0696310775998728,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077181,"numValue":0.0644133981124023,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5583 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,583 | train | mutant | 4,889,737 | 69 | 4,896,318 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50H | R50H | 1 | 1 | 0 | 0 | 50 | R | H | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,250 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.057536 | 0.127663 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077182,"numValue":-0.0575361735637047,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077183,"numValue":0.127662523610832,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5584 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,584 | train | mutant | 4,889,738 | 69 | 4,896,319 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50I | R50I | 1 | 1 | 0 | 0 | 50 | R | I | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,251 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.106244 | 0.075523 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077184,"numValue":0.106243812113952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077185,"numValue":0.0755228674220912,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5586 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,586 | train | mutant | 4,889,740 | 69 | 4,896,321 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50M | R50M | 1 | 1 | 0 | 0 | 50 | R | M | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,254 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.0506 | 0.06058 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077190,"numValue":0.0505996602697316,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077191,"numValue":0.0605803762319647,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5587 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,587 | train | mutant | 4,889,741 | 69 | 4,896,322 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50N | R50N | 1 | 1 | 0 | 0 | 50 | R | N | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,255 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.189629 | 0.135039 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077192,"numValue":0.189628619069244,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077193,"numValue":0.135039429026387,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5588 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,588 | train | mutant | 4,889,742 | 69 | 4,896,323 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50P | R50P | 1 | 1 | 0 | 0 | 50 | R | P | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,256 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.563108 | 0.069182 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077194,"numValue":-0.563108128495164,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077195,"numValue":0.0691820575713527,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5589 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,589 | train | mutant | 4,889,743 | 69 | 4,896,324 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50Q | R50Q | 1 | 1 | 0 | 0 | 50 | R | Q | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,257 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.200403 | 0.068249 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077196,"numValue":0.200403156450388,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077197,"numValue":0.0682485432316693,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5591 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,591 | train | mutant | 4,890,100 | 69 | 4,896,681 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50T | R50T | 1 | 1 | 0 | 0 | 50 | R | T | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,618 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.138339 | 0.062974 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077918,"numValue":0.138338906179995,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077919,"numValue":0.0629743100184325,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5592 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,592 | train | mutant | 4,890,101 | 69 | 4,896,682 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50V | R50V | 1 | 1 | 0 | 0 | 50 | R | V | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,619 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.116818 | 0.058538 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077920,"numValue":0.116817721419278,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077921,"numValue":0.0585380903814349,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5593 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,593 | train | mutant | 4,890,102 | 69 | 4,896,683 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50W | R50W | 1 | 1 | 0 | 0 | 50 | R | W | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,620 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.023883 | 0.068332 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077922,"numValue":-0.0238828381195601,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077923,"numValue":0.0683316464395765,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5594 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,594 | train | mutant | 4,890,103 | 69 | 4,896,684 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R50Y | R50Y | 1 | 1 | 0 | 0 | 50 | R | Y | 9 | CONSERVATION | 1TIN | 58 | null | 50 | A | E | true | false | 94.13134 | 0.526667 | 5,042,621 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.067927 | 0.076691 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077924,"numValue":-0.0679272684071197,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077925,"numValue":0.0766905498136755,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7568,"numValue":9.0,"position":50,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5595 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,595 | train | mutant | 4,889,744 | 69 | 4,896,325 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delV51 | delV51 | 1 | 0 | 1 | 0 | 51 | V | - | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,258 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.999811 | 0.138277 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077198,"numValue":-0.999811023647097,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077199,"numValue":0.138277098337804,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5597 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,597 | train | mutant | 4,889,746 | 69 | 4,896,327 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51C | V51C | 1 | 1 | 0 | 0 | 51 | V | C | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,260 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.334367 | 0.066409 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077202,"numValue":-0.334366571222613,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077203,"numValue":0.0664091076603084,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5598 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,598 | train | mutant | 4,889,747 | 69 | 4,896,328 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51D | V51D | 1 | 1 | 0 | 0 | 51 | V | D | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,261 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.642548 | 0.141803 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077204,"numValue":-0.642547939712098,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077205,"numValue":0.141802574471884,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5599 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,599 | train | mutant | 4,889,748 | 69 | 4,896,329 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51E | V51E | 1 | 1 | 0 | 0 | 51 | V | E | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,262 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.881455 | 0.118074 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077206,"numValue":-0.881454817766959,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077207,"numValue":0.118074300941676,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5600 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,600 | train | mutant | 4,889,749 | 69 | 4,896,330 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51F | V51F | 1 | 1 | 0 | 0 | 51 | V | F | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,263 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.959544 | 0.115175 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077208,"numValue":-0.959544404732671,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077209,"numValue":0.115174910358993,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5601 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,601 | train | mutant | 4,889,750 | 69 | 4,896,331 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51G | V51G | 1 | 1 | 0 | 0 | 51 | V | G | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,264 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.890259 | 0.076595 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077210,"numValue":-0.890259367379066,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077211,"numValue":0.0765951300212035,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5603 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,603 | train | mutant | 4,889,752 | 69 | 4,896,333 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51I | V51I | 1 | 1 | 0 | 0 | 51 | V | I | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,266 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.479179 | 0.069313 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077214,"numValue":-0.47917874676726,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077215,"numValue":0.0693128706754959,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5604 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,604 | train | mutant | 4,889,753 | 69 | 4,896,334 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51K | V51K | 1 | 1 | 0 | 0 | 51 | V | K | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,267 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.933562 | 0.119496 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077216,"numValue":-0.933562445437767,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077217,"numValue":0.119495611408838,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5605 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,605 | train | mutant | 4,889,754 | 69 | 4,896,335 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51L | V51L | 1 | 1 | 0 | 0 | 51 | V | L | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,268 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.693168 | 0.052552 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077218,"numValue":-0.693168292563641,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077219,"numValue":0.0525522302829495,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5606 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,606 | train | mutant | 4,889,755 | 69 | 4,896,336 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51M | V51M | 1 | 1 | 0 | 0 | 51 | V | M | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,269 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.602586 | 0.067719 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077220,"numValue":-0.602585526041583,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077221,"numValue":0.0677186062114943,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5607 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,607 | train | mutant | 4,889,756 | 69 | 4,896,337 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51N | V51N | 1 | 1 | 0 | 0 | 51 | V | N | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,270 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.882096 | 0.184994 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077222,"numValue":-0.882096161848249,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077223,"numValue":0.184994020550103,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5608 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,608 | train | mutant | 4,889,757 | 69 | 4,896,338 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51P | V51P | 1 | 1 | 0 | 0 | 51 | V | P | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,271 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.833141 | 0.081855 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077224,"numValue":-0.833140653158232,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077225,"numValue":0.0818553732497813,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5609 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,609 | train | mutant | 4,889,758 | 69 | 4,896,339 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51Q | V51Q | 1 | 1 | 0 | 0 | 51 | V | Q | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,272 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.637699 | 0.084071 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077226,"numValue":-0.637698678148607,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077227,"numValue":0.0840707210584471,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5610 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,610 | train | mutant | 4,889,759 | 69 | 4,896,340 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51R | V51R | 1 | 1 | 0 | 0 | 51 | V | R | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,273 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.753011 | 0.059725 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077228,"numValue":-0.753011329128263,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077229,"numValue":0.0597252867773442,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5611 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,611 | train | mutant | 4,889,760 | 69 | 4,896,341 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51S | V51S | 1 | 1 | 0 | 0 | 51 | V | S | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,274 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.74222 | 0.057777 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077230,"numValue":-0.74222023768167,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077231,"numValue":0.0577772691321247,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5612 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,612 | train | mutant | 4,889,761 | 69 | 4,896,342 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51T | V51T | 1 | 1 | 0 | 0 | 51 | V | T | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,275 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.715549 | 0.076273 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077232,"numValue":-0.715548759275988,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077233,"numValue":0.0762732794030731,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5613 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,613 | train | mutant | 4,890,097 | 69 | 4,896,678 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51W | V51W | 1 | 1 | 0 | 0 | 51 | V | W | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,615 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.820853 | 0.102485 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077912,"numValue":-0.82085339807897,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077913,"numValue":0.102484689740903,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5614 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,614 | train | mutant | 4,890,098 | 69 | 4,896,679 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | V51Y | V51Y | 1 | 1 | 0 | 0 | 51 | V | Y | 9 | CONSERVATION | 1TIN | 58 | null | 51 | A | E | true | true | 3.896757 | 0.225 | 5,042,616 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.681892 | 0.09596 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077914,"numValue":-0.681892364928446,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077915,"numValue":0.095959958824965,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7569,"numValue":9.0,"position":51,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5615 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,615 | train | mutant | 64 | 69 | 72 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52A | R52A | 1 | 1 | 0 | 0 | 52 | R | A | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 83 | ProTherm | 2.5 | DSC | Thermal | dialyzate | null | 1TIN_A:R52A | 65.7 | -5.2 | null | null | 43 | 0.24 | null | null | null | null | null | null | null | null | null | null | yes | TM|DTM|DH|DCP|REVERSIBILITY | AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|_PDB_CHAIN_MUTATION | 10 | ARTICLE | Disulfide bond effects on protein stability: designed variants of Cucurbita maxima trypsin inhibitor-V. | 2,001 | 10.1110/ps.26801 | 11266603 | Protein Sci;10;149-60 | 6 | Zavodszky M|Zolkiewski M|Wen L|Chen C W|Huang J K|Krishnamoorthi R | [{"numValue":2.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"dialyzate","type":"BUFFER"},{"numValue":null,"strValue":"1TIN_A:R52A","type":"_PDB_CHAIN_MUTATION"}] | [{"datasets":[],"id":282,"numValue":65.7,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","Saraboji_S1791.csv"],"id":283,"numValue":-5.2,"references":[],"strValue":null,"type":"DTM"},{"datasets":[],"id":284,"numValue":43.0,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":28... | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:5616 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,616 | train | mutant | 64 | 69 | 72 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52A | R52A | 1 | 1 | 0 | 0 | 52 | R | A | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,277 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.006667 | 0.048999 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077236,"numValue":-0.00666661005296245,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077237,"numValue":0.0489988551505229,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5618 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,618 | train | mutant | 65 | 69 | 73 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52Q | R52Q | 1 | 1 | 0 | 0 | 52 | R | Q | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,290 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.081857 | 0.046938 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077262,"numValue":-0.0818566148046899,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077263,"numValue":0.0469383328376755,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5619 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,619 | train | mutant | 4,889,762 | 69 | 4,896,343 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delR52 | delR52 | 1 | 0 | 1 | 0 | 52 | R | - | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,276 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.844573 | 0.094378 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077234,"numValue":-0.844573034705466,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077235,"numValue":0.0943784158003898,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5620 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,620 | train | mutant | 4,889,763 | 69 | 4,896,344 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52C | R52C | 1 | 1 | 0 | 0 | 52 | R | C | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,278 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.03972 | 0.058751 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077238,"numValue":-0.0397198606245934,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077239,"numValue":0.0587512599611851,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5621 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,621 | train | mutant | 4,889,764 | 69 | 4,896,345 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52D | R52D | 1 | 1 | 0 | 0 | 52 | R | D | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,279 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.273425 | 0.101148 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077240,"numValue":-0.273425118434824,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077241,"numValue":0.101148128891418,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5622 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,622 | train | mutant | 4,889,765 | 69 | 4,896,346 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52E | R52E | 1 | 1 | 0 | 0 | 52 | R | E | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,280 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.058987 | 0.064704 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077242,"numValue":-0.0589873533228718,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077243,"numValue":0.0647041918642672,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5623 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,623 | train | mutant | 4,889,766 | 69 | 4,896,347 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52F | R52F | 1 | 1 | 0 | 0 | 52 | R | F | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,281 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.060126 | 0.040692 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077244,"numValue":-0.0601263449999367,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077245,"numValue":0.0406917821954726,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5624 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,624 | train | mutant | 4,889,767 | 69 | 4,896,348 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52G | R52G | 1 | 1 | 0 | 0 | 52 | R | G | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,282 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.307936 | 0.058424 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077246,"numValue":-0.307935576604672,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077247,"numValue":0.0584242361976019,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5625 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,625 | train | mutant | 4,889,768 | 69 | 4,896,349 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52H | R52H | 1 | 1 | 0 | 0 | 52 | R | H | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,283 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.138005 | 0.080492 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077248,"numValue":-0.138004675999877,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077249,"numValue":0.080491660134251,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5626 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,626 | train | mutant | 4,889,769 | 69 | 4,896,350 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52I | R52I | 1 | 1 | 0 | 0 | 52 | R | I | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,284 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.138458 | 0.051081 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077250,"numValue":0.13845766360604,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077251,"numValue":0.0510806818258608,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5627 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,627 | train | mutant | 4,889,770 | 69 | 4,896,351 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52K | R52K | 1 | 1 | 0 | 0 | 52 | R | K | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,285 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.248119 | 0.066359 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077252,"numValue":-0.248118720654427,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077253,"numValue":0.0663591215800732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5628 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,628 | train | mutant | 4,889,771 | 69 | 4,896,352 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52L | R52L | 1 | 1 | 0 | 0 | 52 | R | L | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,286 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.010391 | 0.033228 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077254,"numValue":-0.010391274778909,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077255,"numValue":0.033228264829877,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5629 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,629 | train | mutant | 4,889,772 | 69 | 4,896,353 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52M | R52M | 1 | 1 | 0 | 0 | 52 | R | M | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,287 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.041997 | 0.044634 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077256,"numValue":-0.0419969443012531,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077257,"numValue":0.044633773011081,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5630 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,630 | train | mutant | 4,889,773 | 69 | 4,896,354 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52N | R52N | 1 | 1 | 0 | 0 | 52 | R | N | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,288 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.09293 | 0.065587 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077258,"numValue":-0.0929304748801149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077259,"numValue":0.0655867934559213,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5631 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,631 | train | mutant | 4,889,774 | 69 | 4,896,355 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52P | R52P | 1 | 1 | 0 | 0 | 52 | R | P | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,289 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.09772 | 0.042228 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077260,"numValue":-0.0977197279563544,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077261,"numValue":0.0422282423820244,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5632 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,632 | train | mutant | 4,890,092 | 69 | 4,896,673 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52S | R52S | 1 | 1 | 0 | 0 | 52 | R | S | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,610 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.290654 | 0.040258 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077902,"numValue":-0.29065430185699,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077903,"numValue":0.0402580206968445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5633 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,633 | train | mutant | 4,890,093 | 69 | 4,896,674 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52T | R52T | 1 | 1 | 0 | 0 | 52 | R | T | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,611 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.033018 | 0.041937 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077904,"numValue":-0.0330181631502997,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077905,"numValue":0.0419368188559306,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5634 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,634 | train | mutant | 4,890,094 | 69 | 4,896,675 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52V | R52V | 1 | 1 | 0 | 0 | 52 | R | V | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,612 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.050899 | 0.037874 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077906,"numValue":0.0508992528672534,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077907,"numValue":0.0378736054980096,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5635 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,635 | train | mutant | 4,890,095 | 69 | 4,896,676 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52W | R52W | 1 | 1 | 0 | 0 | 52 | R | W | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,613 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.213007 | 0.044891 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077908,"numValue":-0.213007187966849,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077909,"numValue":0.0448914136481751,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5636 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,636 | train | mutant | 4,890,096 | 69 | 4,896,677 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R52Y | R52Y | 1 | 1 | 0 | 0 | 52 | R | Y | 5 | CONSERVATION | 1TIN | 58 | null | 52 | A | E | true | true | 53.064429 | 0.348333 | 5,042,614 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.246053 | 0.056994 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077910,"numValue":-0.246052521376744,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077911,"numValue":0.056993946949289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7570,"numValue":5.0,"position":52,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5637 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,637 | train | mutant | 4,889,775 | 69 | 4,896,356 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delI53 | delI53 | 1 | 0 | 1 | 0 | 53 | I | - | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,291 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.926715 | 0.116163 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077264,"numValue":-0.926715036200426,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077265,"numValue":0.116163296027574,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5638 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,638 | train | mutant | 4,889,776 | 69 | 4,896,357 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53A | I53A | 1 | 1 | 0 | 0 | 53 | I | A | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,292 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.758077 | 0.079733 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077266,"numValue":-0.758076963123297,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077267,"numValue":0.0797326562334303,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5639 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,639 | train | mutant | 4,889,777 | 69 | 4,896,358 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53C | I53C | 1 | 1 | 0 | 0 | 53 | I | C | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,293 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.655278 | 0.09086 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077268,"numValue":-0.655278375913099,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077269,"numValue":0.0908603170215633,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5640 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,640 | train | mutant | 4,889,778 | 69 | 4,896,359 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53D | I53D | 1 | 1 | 0 | 0 | 53 | I | D | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,294 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.544326 | 0.142556 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077270,"numValue":-0.544326371662958,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077271,"numValue":0.142555604514304,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5642 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,642 | train | mutant | 4,889,780 | 69 | 4,896,361 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53F | I53F | 1 | 1 | 0 | 0 | 53 | I | F | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,296 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.660147 | 0.150795 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077274,"numValue":-0.660146620671208,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077275,"numValue":0.150794940752635,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5643 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,643 | train | mutant | 4,889,781 | 69 | 4,896,362 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53G | I53G | 1 | 1 | 0 | 0 | 53 | I | G | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,297 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.791533 | 0.085434 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077276,"numValue":-0.791532819362769,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077277,"numValue":0.0854336514545784,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5644 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,644 | train | mutant | 4,889,782 | 69 | 4,896,363 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53H | I53H | 1 | 1 | 0 | 0 | 53 | I | H | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,298 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.295146 | 0.114029 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077278,"numValue":-0.295146031593889,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077279,"numValue":0.114028991165409,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5645 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,645 | train | mutant | 4,890,080 | 69 | 4,896,661 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53K | I53K | 1 | 1 | 0 | 0 | 53 | I | K | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,598 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.856266 | 0.108638 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077878,"numValue":-0.856265602977034,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077879,"numValue":0.108637943829463,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5647 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,647 | train | mutant | 4,890,082 | 69 | 4,896,663 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53M | I53M | 1 | 1 | 0 | 0 | 53 | I | M | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,600 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.73093 | 0.088016 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077882,"numValue":-0.730930455013437,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077883,"numValue":0.0880157347903548,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5648 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,648 | train | mutant | 4,890,083 | 69 | 4,896,664 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53N | I53N | 1 | 1 | 0 | 0 | 53 | I | N | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,601 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.756304 | 0.178453 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077884,"numValue":-0.756304328604087,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077885,"numValue":0.178453185407452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5650 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,650 | train | mutant | 4,890,085 | 69 | 4,896,666 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53Q | I53Q | 1 | 1 | 0 | 0 | 53 | I | Q | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,603 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.89732 | 0.097005 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077888,"numValue":-0.897320459012314,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077889,"numValue":0.0970049342064112,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5651 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,651 | train | mutant | 4,890,086 | 69 | 4,896,667 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53R | I53R | 1 | 1 | 0 | 0 | 53 | I | R | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,604 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.936766 | 0.06119 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077890,"numValue":-0.936765855031124,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077891,"numValue":0.0611897097888703,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5652 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,652 | train | mutant | 4,890,087 | 69 | 4,896,668 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53S | I53S | 1 | 1 | 0 | 0 | 53 | I | S | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,605 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.865068 | 0.072862 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077892,"numValue":-0.865067687472873,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077893,"numValue":0.0728618553818687,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5653 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,653 | train | mutant | 4,890,088 | 69 | 4,896,669 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53T | I53T | 1 | 1 | 0 | 0 | 53 | I | T | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,606 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.833484 | 0.114477 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077894,"numValue":-0.833483700177556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077895,"numValue":0.114477390416475,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5654 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,654 | train | mutant | 4,890,089 | 69 | 4,896,670 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53V | I53V | 1 | 1 | 0 | 0 | 53 | I | V | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,607 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.157586 | 0.048403 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077896,"numValue":-0.157586066167451,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077897,"numValue":0.0484028818040474,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5655 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,655 | train | mutant | 4,890,090 | 69 | 4,896,671 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53W | I53W | 1 | 1 | 0 | 0 | 53 | I | W | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,608 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.834899 | 0.074423 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077898,"numValue":-0.834899162741163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077899,"numValue":0.0744231556633681,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5656 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,656 | train | mutant | 4,890,091 | 69 | 4,896,672 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I53Y | I53Y | 1 | 1 | 0 | 0 | 53 | I | Y | 8 | CONSERVATION | 1TIN | 58 | null | 53 | A | E | false | false | 0 | 0.201579 | 5,042,609 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.69513 | 0.118539 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077900,"numValue":-0.695129859351559,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077901,"numValue":0.118539254258191,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7571,"numValue":8.0,"position":53,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5657 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,657 | train | mutant | 4,889,783 | 69 | 4,896,364 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delW54 | delW54 | 1 | 0 | 1 | 0 | 54 | W | - | 5 | CONSERVATION | 1TIN | 58 | null | 54 | A | E | true | true | 16.496131 | 0.325833 | 5,042,299 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.005051 | 0.107427 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077280,"numValue":-1.00505119507132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077281,"numValue":0.107427337825783,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7572,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5658 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,658 | train | mutant | 4,889,784 | 69 | 4,896,365 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | W54A | W54A | 1 | 1 | 0 | 0 | 54 | W | A | 5 | CONSERVATION | 1TIN | 58 | null | 54 | A | E | true | true | 16.496131 | 0.325833 | 5,042,300 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.839241 | 0.083815 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077282,"numValue":-0.839241456050289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077283,"numValue":0.0838145109085304,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7572,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5659 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,659 | train | mutant | 4,889,785 | 69 | 4,896,366 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | W54C | W54C | 1 | 1 | 0 | 0 | 54 | W | C | 5 | CONSERVATION | 1TIN | 58 | null | 54 | A | E | true | true | 16.496131 | 0.325833 | 5,042,301 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.405565 | 0.060914 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077284,"numValue":-0.405565156878528,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077285,"numValue":0.0609142285475454,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7572,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5661 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,661 | train | mutant | 4,889,787 | 69 | 4,896,368 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | W54E | W54E | 1 | 1 | 0 | 0 | 54 | W | E | 5 | CONSERVATION | 1TIN | 58 | null | 54 | A | E | true | true | 16.496131 | 0.325833 | 5,042,303 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.286795 | 0.060301 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077288,"numValue":-0.286794595542791,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077289,"numValue":0.0603009813936452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7572,"numValue":5.0,"position":54,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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