row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5461934 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,934 | train | mutant | 5,053,376 | 5,059,372 | 5,060,041 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | G1958R | G1958R | 1 | 1 | 0 | 0 | 1,958 | G | R | 2 | CONSERVATION | null | false | false | null | null | 5,439,880 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.015892 | 0.038987 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872442,"numValue":0.0158915812430097,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872443,"numValue":0.0389867556851304,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461581,"numValue":2.0,"position":1958,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461935 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,935 | train | mutant | 5,053,377 | 5,059,372 | 5,060,042 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | G1958S | G1958S | 1 | 1 | 0 | 0 | 1,958 | G | S | 2 | CONSERVATION | null | false | false | null | null | 5,439,881 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.020864 | 0.055427 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872444,"numValue":-0.0208638812585509,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872445,"numValue":0.0554269780280048,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461581,"numValue":2.0,"position":1958,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461936 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,936 | train | mutant | 5,053,378 | 5,059,372 | 5,060,043 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | G1958T | G1958T | 1 | 1 | 0 | 0 | 1,958 | G | T | 2 | CONSERVATION | null | false | false | null | null | 5,439,882 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.052191 | 0.049483 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872446,"numValue":-0.0521912112454582,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872447,"numValue":0.0494834926051727,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461581,"numValue":2.0,"position":1958,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461937 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,937 | train | mutant | 5,053,379 | 5,059,372 | 5,060,044 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | G1958V | G1958V | 1 | 1 | 0 | 0 | 1,958 | G | V | 2 | CONSERVATION | null | false | false | null | null | 5,439,883 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.047377 | 0.032222 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872448,"numValue":-0.0473771416836956,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872449,"numValue":0.0322216540313307,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461581,"numValue":2.0,"position":1958,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461938 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,938 | train | mutant | 5,053,380 | 5,059,372 | 5,060,045 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | G1958W | G1958W | 1 | 1 | 0 | 0 | 1,958 | G | W | 2 | CONSERVATION | null | false | false | null | null | 5,439,884 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.023702 | 0.038582 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872450,"numValue":-0.0237019100370791,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872451,"numValue":0.0385819479076395,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461581,"numValue":2.0,"position":1958,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461939 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,939 | train | mutant | 5,053,381 | 5,059,372 | 5,060,046 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | G1958Y | G1958Y | 1 | 1 | 0 | 0 | 1,958 | G | Y | 2 | CONSERVATION | null | false | false | null | null | 5,439,885 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872452,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872453,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461581,"numValue":2.0,"position":1958,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461940 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,940 | train | mutant | 5,053,348 | 5,059,372 | 5,060,013 | 2,610 | 2,609 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | delT1959 | delT1959 | 1 | 0 | 1 | 0 | 1,959 | T | - | 4 | CONSERVATION | null | false | false | null | null | 5,439,852 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872386,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872387,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461941 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,941 | train | mutant | 5,053,349 | 5,059,372 | 5,060,014 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959A | T1959A | 1 | 1 | 0 | 0 | 1,959 | T | A | 4 | CONSERVATION | null | false | false | null | null | 5,439,853 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.035965 | 0.070646 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872388,"numValue":-0.0359647702049172,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872389,"numValue":0.0706460798424556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461942 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,942 | train | mutant | 5,053,350 | 5,059,372 | 5,060,015 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959C | T1959C | 1 | 1 | 0 | 0 | 1,959 | T | C | 4 | CONSERVATION | null | false | false | null | null | 5,439,854 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872390,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872391,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461943 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,943 | train | mutant | 5,053,351 | 5,059,372 | 5,060,016 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959D | T1959D | 1 | 1 | 0 | 0 | 1,959 | T | D | 4 | CONSERVATION | null | false | false | null | null | 5,439,855 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872392,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872393,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461944 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,944 | train | mutant | 5,053,352 | 5,059,372 | 5,060,017 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959E | T1959E | 1 | 1 | 0 | 0 | 1,959 | T | E | 4 | CONSERVATION | null | false | false | null | null | 5,439,856 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872394,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872395,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461945 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,945 | train | mutant | 5,053,353 | 5,059,372 | 5,060,018 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959F | T1959F | 1 | 1 | 0 | 0 | 1,959 | T | F | 4 | CONSERVATION | null | false | false | null | null | 5,439,857 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872396,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872397,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461946 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,946 | train | mutant | 5,053,354 | 5,059,372 | 5,060,019 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959G | T1959G | 1 | 1 | 0 | 0 | 1,959 | T | G | 4 | CONSERVATION | null | false | false | null | null | 5,439,858 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872398,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872399,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461947 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,947 | train | mutant | 5,053,355 | 5,059,372 | 5,060,020 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959H | T1959H | 1 | 1 | 0 | 0 | 1,959 | T | H | 4 | CONSERVATION | null | false | false | null | null | 5,439,859 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872400,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872401,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461948 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,948 | train | mutant | 5,053,356 | 5,059,372 | 5,060,021 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959I | T1959I | 1 | 1 | 0 | 0 | 1,959 | T | I | 4 | CONSERVATION | null | false | false | null | null | 5,439,860 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.130589 | 0.435631 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872402,"numValue":-0.13058934139799,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872403,"numValue":0.435630793903683,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461949 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,949 | train | mutant | 5,053,357 | 5,059,372 | 5,060,022 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959K | T1959K | 1 | 1 | 0 | 0 | 1,959 | T | K | 4 | CONSERVATION | null | false | false | null | null | 5,439,861 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.002313 | 0.34719 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872404,"numValue":0.00231320044201267,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872405,"numValue":0.347189629658707,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461950 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,950 | train | mutant | 5,053,358 | 5,059,372 | 5,060,023 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959L | T1959L | 1 | 1 | 0 | 0 | 1,959 | T | L | 4 | CONSERVATION | null | false | false | null | null | 5,439,862 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872406,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872407,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461951 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,951 | train | mutant | 5,053,359 | 5,059,372 | 5,060,024 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959M | T1959M | 1 | 1 | 0 | 0 | 1,959 | T | M | 4 | CONSERVATION | null | false | false | null | null | 5,439,863 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.014179 | 0.097209 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872408,"numValue":0.0141791045586564,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872409,"numValue":0.0972087412871811,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461952 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,952 | train | mutant | 5,053,360 | 5,059,372 | 5,060,025 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959N | T1959N | 1 | 1 | 0 | 0 | 1,959 | T | N | 4 | CONSERVATION | null | false | false | null | null | 5,439,864 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.106541 | 0.97901 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872410,"numValue":-0.106541072257145,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872411,"numValue":0.979010455196872,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461953 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,953 | train | mutant | 5,053,361 | 5,059,372 | 5,060,026 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959P | T1959P | 1 | 1 | 0 | 0 | 1,959 | T | P | 4 | CONSERVATION | null | false | false | null | null | 5,439,865 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.086951 | 0.485979 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872412,"numValue":0.0869513141293115,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872413,"numValue":0.485978620362622,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461954 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,954 | train | mutant | 5,053,362 | 5,059,372 | 5,060,027 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959Q | T1959Q | 1 | 1 | 0 | 0 | 1,959 | T | Q | 4 | CONSERVATION | null | false | false | null | null | 5,439,866 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872414,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872415,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461955 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,955 | train | mutant | 5,053,363 | 5,059,372 | 5,060,028 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959R | T1959R | 1 | 1 | 0 | 0 | 1,959 | T | R | 4 | CONSERVATION | null | false | false | null | null | 5,439,867 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.106023 | 0.221534 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872416,"numValue":0.106022683532121,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872417,"numValue":0.221533950607313,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461957 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,957 | train | mutant | 5,053,365 | 5,059,372 | 5,060,030 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959V | T1959V | 1 | 1 | 0 | 0 | 1,959 | T | V | 4 | CONSERVATION | null | false | false | null | null | 5,439,869 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.060163 | 0.295164 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872420,"numValue":-0.0601629902990517,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872421,"numValue":0.295164468395267,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461958 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,958 | train | mutant | 5,053,366 | 5,059,372 | 5,060,031 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959W | T1959W | 1 | 1 | 0 | 0 | 1,959 | T | W | 4 | CONSERVATION | null | false | false | null | null | 5,439,870 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872422,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872423,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461959 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,959 | train | mutant | 5,053,367 | 5,059,372 | 5,060,032 | 2,610 | 2,610 | 8,257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | 8257 | E3 ubiquitin-protein ligase HECTD1 | Homo sapiens | 1 | Q9ULT8 | IPR002110|IPR036770|IPR011989|IPR016024|IPR041200|IPR008979|IPR000569|IPR035983|IPR045322|IPR010606|IPR037252|IPR012919 | 2.3.2.26 | T1959Y | T1959Y | 1 | 1 | 0 | 0 | 1,959 | T | Y | 4 | CONSERVATION | null | false | false | null | null | 5,439,871 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12872424,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12872425,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1461582,"numValue":4.0,"position":1959,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||||||
fireprotdb:5461960 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,960 | train | mutant | 5,054,066 | 5,060,731 | 5,060,732 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delF114 | delF114 | 1 | 0 | 1 | 0 | 114 | F | - | 9 | CONSERVATION | null | false | false | null | null | 5,440,570 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873822,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873823,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461962 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,962 | train | mutant | 5,054,068 | 5,060,731 | 5,060,734 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114C | F114C | 1 | 1 | 0 | 0 | 114 | F | C | 9 | CONSERVATION | null | false | false | null | null | 5,440,572 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.042399 | 0.37989 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873826,"numValue":-1.04239896669583,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873827,"numValue":0.379890098966849,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461963 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,963 | train | mutant | 5,054,069 | 5,060,731 | 5,060,735 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114D | F114D | 1 | 1 | 0 | 0 | 114 | F | D | 9 | CONSERVATION | null | false | false | null | null | 5,440,573 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.684701 | 0.278756 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873828,"numValue":-0.684700667711649,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873829,"numValue":0.278756462535602,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461964 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,964 | train | mutant | 5,054,070 | 5,060,731 | 5,060,736 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114E | F114E | 1 | 1 | 0 | 0 | 114 | F | E | 9 | CONSERVATION | null | false | false | null | null | 5,440,574 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.74546 | 0.269281 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873830,"numValue":-0.74545955164953,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873831,"numValue":0.269280865894702,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461965 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,965 | train | mutant | 5,055,667 | 5,060,731 | 5,062,333 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114G | F114G | 1 | 1 | 0 | 0 | 114 | F | G | 9 | CONSERVATION | null | false | false | null | null | 5,442,175 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.967968 | 0.25034 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877032,"numValue":-0.967967738048018,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877033,"numValue":0.250340169498154,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461966 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,966 | train | mutant | 5,055,668 | 5,060,731 | 5,062,334 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114H | F114H | 1 | 1 | 0 | 0 | 114 | F | H | 9 | CONSERVATION | null | false | false | null | null | 5,442,176 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.375003 | 0.406185 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877034,"numValue":-0.375002637684329,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877035,"numValue":0.406185126333507,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461967 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,967 | train | mutant | 5,055,669 | 5,060,731 | 5,062,335 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114I | F114I | 1 | 1 | 0 | 0 | 114 | F | I | 9 | CONSERVATION | null | false | false | null | null | 5,442,177 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877036,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877037,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461968 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,968 | train | mutant | 5,055,670 | 5,060,731 | 5,062,336 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114K | F114K | 1 | 1 | 0 | 0 | 114 | F | K | 9 | CONSERVATION | null | false | false | null | null | 5,442,178 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877038,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877039,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461969 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,969 | train | mutant | 5,055,671 | 5,060,731 | 5,062,337 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114L | F114L | 1 | 1 | 0 | 0 | 114 | F | L | 9 | CONSERVATION | null | false | false | null | null | 5,442,179 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.808885 | 0.20066 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877040,"numValue":-0.808884774296425,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877041,"numValue":0.200660147343201,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461970 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,970 | train | mutant | 5,055,672 | 5,060,731 | 5,062,338 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114M | F114M | 1 | 1 | 0 | 0 | 114 | F | M | 9 | CONSERVATION | null | false | false | null | null | 5,442,180 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.660761 | 0.269592 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877042,"numValue":-0.660760658678859,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877043,"numValue":0.269591673696501,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461971 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,971 | train | mutant | 5,055,673 | 5,060,731 | 5,062,339 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114N | F114N | 1 | 1 | 0 | 0 | 114 | F | N | 9 | CONSERVATION | null | false | false | null | null | 5,442,181 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877044,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877045,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461972 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,972 | train | mutant | 5,055,674 | 5,060,731 | 5,062,340 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114P | F114P | 1 | 1 | 0 | 0 | 114 | F | P | 9 | CONSERVATION | null | false | false | null | null | 5,442,182 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877046,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877047,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461974 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,974 | train | mutant | 5,055,676 | 5,060,731 | 5,062,342 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114R | F114R | 1 | 1 | 0 | 0 | 114 | F | R | 9 | CONSERVATION | null | false | false | null | null | 5,442,184 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.497839 | 0.262148 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877050,"numValue":-0.497838758875748,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877051,"numValue":0.262148056693054,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461975 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,975 | train | mutant | 5,055,677 | 5,060,731 | 5,062,343 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114S | F114S | 1 | 1 | 0 | 0 | 114 | F | S | 9 | CONSERVATION | null | false | false | null | null | 5,442,185 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.385127 | 0.212649 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877052,"numValue":-0.385127195443231,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877053,"numValue":0.212649424218651,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461976 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,976 | train | mutant | 5,055,678 | 5,060,731 | 5,062,344 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114T | F114T | 1 | 1 | 0 | 0 | 114 | F | T | 9 | CONSERVATION | null | false | false | null | null | 5,442,186 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.634305 | 0.728555 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877054,"numValue":-0.634304708805237,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877055,"numValue":0.728555067745789,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461977 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,977 | train | mutant | 5,055,679 | 5,060,731 | 5,062,345 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114V | F114V | 1 | 1 | 0 | 0 | 114 | F | V | 9 | CONSERVATION | null | false | false | null | null | 5,442,187 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.907583 | 0.148594 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877056,"numValue":-0.907582749464682,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877057,"numValue":0.14859428584198,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461978 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,978 | train | mutant | 5,055,680 | 5,060,731 | 5,062,346 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114W | F114W | 1 | 1 | 0 | 0 | 114 | F | W | 9 | CONSERVATION | null | false | false | null | null | 5,442,188 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.157713 | 0.589812 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877058,"numValue":-1.15771296407881,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877059,"numValue":0.589811946275837,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461979 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,979 | train | mutant | 5,055,681 | 5,060,731 | 5,062,347 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | F114Y | F114Y | 1 | 1 | 0 | 0 | 114 | F | Y | 9 | CONSERVATION | null | false | false | null | null | 5,442,189 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.004118 | 0.425874 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877060,"numValue":-1.00411759682616,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877061,"numValue":0.425874430264175,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462347,"numValue":9.0,"position":114,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461980 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,980 | train | mutant | 5,054,071 | 5,060,731 | 5,060,737 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delI115 | delI115 | 1 | 0 | 1 | 0 | 115 | I | - | 8 | CONSERVATION | null | false | false | null | null | 5,440,575 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873832,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873833,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461981 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,981 | train | mutant | 5,054,072 | 5,060,731 | 5,060,738 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115A | I115A | 1 | 1 | 0 | 0 | 115 | I | A | 8 | CONSERVATION | null | false | false | null | null | 5,440,576 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873834,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873835,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461982 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,982 | train | mutant | 5,054,073 | 5,060,731 | 5,060,739 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115C | I115C | 1 | 1 | 0 | 0 | 115 | I | C | 8 | CONSERVATION | null | false | false | null | null | 5,440,577 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873836,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873837,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461983 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,983 | train | mutant | 5,054,074 | 5,060,731 | 5,060,740 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115D | I115D | 1 | 1 | 0 | 0 | 115 | I | D | 8 | CONSERVATION | null | false | false | null | null | 5,440,578 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873838,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873839,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461984 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,984 | train | mutant | 5,054,075 | 5,060,731 | 5,060,741 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115E | I115E | 1 | 1 | 0 | 0 | 115 | I | E | 8 | CONSERVATION | null | false | false | null | null | 5,440,579 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873840,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873841,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461985 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,985 | train | mutant | 5,054,076 | 5,060,731 | 5,060,742 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115F | I115F | 1 | 1 | 0 | 0 | 115 | I | F | 8 | CONSERVATION | null | false | false | null | null | 5,440,580 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873842,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873843,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461986 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,986 | train | mutant | 5,054,077 | 5,060,731 | 5,060,743 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115G | I115G | 1 | 1 | 0 | 0 | 115 | I | G | 8 | CONSERVATION | null | false | false | null | null | 5,440,581 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873844,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873845,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461987 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,987 | train | mutant | 5,054,078 | 5,060,731 | 5,060,744 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115H | I115H | 1 | 1 | 0 | 0 | 115 | I | H | 8 | CONSERVATION | null | false | false | null | null | 5,440,582 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873846,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873847,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461988 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,988 | train | mutant | 5,055,655 | 5,060,731 | 5,062,321 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115K | I115K | 1 | 1 | 0 | 0 | 115 | I | K | 8 | CONSERVATION | null | false | false | null | null | 5,442,163 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877008,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877009,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461989 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,989 | train | mutant | 5,055,656 | 5,060,731 | 5,062,322 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115L | I115L | 1 | 1 | 0 | 0 | 115 | I | L | 8 | CONSERVATION | null | false | false | null | null | 5,442,164 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877010,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877011,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461991 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,991 | train | mutant | 5,055,658 | 5,060,731 | 5,062,324 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115N | I115N | 1 | 1 | 0 | 0 | 115 | I | N | 8 | CONSERVATION | null | false | false | null | null | 5,442,166 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877014,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877015,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461992 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,992 | train | mutant | 5,055,659 | 5,060,731 | 5,062,325 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115P | I115P | 1 | 1 | 0 | 0 | 115 | I | P | 8 | CONSERVATION | null | false | false | null | null | 5,442,167 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877016,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877017,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461994 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,994 | train | mutant | 5,055,661 | 5,060,731 | 5,062,327 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115R | I115R | 1 | 1 | 0 | 0 | 115 | I | R | 8 | CONSERVATION | null | false | false | null | null | 5,442,169 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877020,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877021,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461995 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,995 | train | mutant | 5,055,662 | 5,060,731 | 5,062,328 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115S | I115S | 1 | 1 | 0 | 0 | 115 | I | S | 8 | CONSERVATION | null | false | false | null | null | 5,442,170 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877022,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877023,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461996 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,996 | train | mutant | 5,055,663 | 5,060,731 | 5,062,329 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115T | I115T | 1 | 1 | 0 | 0 | 115 | I | T | 8 | CONSERVATION | null | false | false | null | null | 5,442,171 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.244303 | 0.710884 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877024,"numValue":-0.244302721563488,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877025,"numValue":0.710884099113084,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5461998 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,461,998 | train | mutant | 5,055,665 | 5,060,731 | 5,062,331 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I115W | I115W | 1 | 1 | 0 | 0 | 115 | I | W | 8 | CONSERVATION | null | false | false | null | null | 5,442,173 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.619359 | 0.428373 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877028,"numValue":-0.619359310067973,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877029,"numValue":0.428372640549468,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462348,"numValue":8.0,"position":115,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462000 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,000 | train | mutant | 5,054,079 | 5,060,731 | 5,060,745 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delD116 | delD116 | 1 | 0 | 1 | 0 | 116 | D | - | 7 | CONSERVATION | null | false | false | null | null | 5,440,583 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.893183 | 0.436911 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873848,"numValue":-0.893182768618819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873849,"numValue":0.436911171890026,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462001 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,001 | train | mutant | 5,054,080 | 5,060,731 | 5,060,746 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116A | D116A | 1 | 1 | 0 | 0 | 116 | D | A | 7 | CONSERVATION | null | false | false | null | null | 5,440,584 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.77661 | 0.119857 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873850,"numValue":-0.776610244430735,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873851,"numValue":0.119856822823432,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462002 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,002 | train | mutant | 5,054,081 | 5,060,731 | 5,060,747 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116C | D116C | 1 | 1 | 0 | 0 | 116 | D | C | 7 | CONSERVATION | null | false | false | null | null | 5,440,585 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.821871 | 0.224804 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873852,"numValue":-0.821871407102833,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873853,"numValue":0.22480387360504,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462003 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,003 | train | mutant | 5,055,638 | 5,060,731 | 5,062,304 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116E | D116E | 1 | 1 | 0 | 0 | 116 | D | E | 7 | CONSERVATION | null | false | false | null | null | 5,442,146 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.386837 | 0.097489 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876974,"numValue":-0.386837149130123,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876975,"numValue":0.0974891958694103,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462004 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,004 | train | mutant | 5,055,639 | 5,060,731 | 5,062,305 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116F | D116F | 1 | 1 | 0 | 0 | 116 | D | F | 7 | CONSERVATION | null | false | false | null | null | 5,442,147 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.748505 | 0.376215 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876976,"numValue":-0.748505442568314,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876977,"numValue":0.376215349966041,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462005 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,005 | train | mutant | 5,055,640 | 5,060,731 | 5,062,306 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116G | D116G | 1 | 1 | 0 | 0 | 116 | D | G | 7 | CONSERVATION | null | false | false | null | null | 5,442,148 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.80474 | 0.087601 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876978,"numValue":-0.804739946671689,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876979,"numValue":0.0876014470950755,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462006 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,006 | train | mutant | 5,055,641 | 5,060,731 | 5,062,307 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116H | D116H | 1 | 1 | 0 | 0 | 116 | D | H | 7 | CONSERVATION | null | false | false | null | null | 5,442,149 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.616229 | 0.161136 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876980,"numValue":-0.616228566320801,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876981,"numValue":0.161136351120876,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462007 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,007 | train | mutant | 5,055,642 | 5,060,731 | 5,062,308 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116I | D116I | 1 | 1 | 0 | 0 | 116 | D | I | 7 | CONSERVATION | null | false | false | null | null | 5,442,150 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.796144 | 0.265415 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876982,"numValue":-0.796144144460504,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876983,"numValue":0.265415497133663,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462008 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,008 | train | mutant | 5,055,643 | 5,060,731 | 5,062,309 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116K | D116K | 1 | 1 | 0 | 0 | 116 | D | K | 7 | CONSERVATION | null | false | false | null | null | 5,442,151 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.8246 | 0.441557 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876984,"numValue":-0.824599977813124,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876985,"numValue":0.441556560970412,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462009 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,009 | train | mutant | 5,055,644 | 5,060,731 | 5,062,310 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116L | D116L | 1 | 1 | 0 | 0 | 116 | D | L | 7 | CONSERVATION | null | false | false | null | null | 5,442,152 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.881412 | 0.144123 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876986,"numValue":-0.881411838693433,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876987,"numValue":0.14412319941133,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462011 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,011 | train | mutant | 5,055,646 | 5,060,731 | 5,062,312 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116N | D116N | 1 | 1 | 0 | 0 | 116 | D | N | 7 | CONSERVATION | null | false | false | null | null | 5,442,154 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.599152 | 0.121449 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876990,"numValue":-0.599151822875307,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876991,"numValue":0.121448914718598,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462012 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,012 | train | mutant | 5,055,647 | 5,060,731 | 5,062,313 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116P | D116P | 1 | 1 | 0 | 0 | 116 | D | P | 7 | CONSERVATION | null | false | false | null | null | 5,442,155 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.951274 | 0.212496 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876992,"numValue":-0.951273675112311,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876993,"numValue":0.21249587188436,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462013 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,013 | train | mutant | 5,055,648 | 5,060,731 | 5,062,314 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116Q | D116Q | 1 | 1 | 0 | 0 | 116 | D | Q | 7 | CONSERVATION | null | false | false | null | null | 5,442,156 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.928725 | 0.192107 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876994,"numValue":-0.928724824480264,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876995,"numValue":0.19210705885827,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462014 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,014 | train | mutant | 5,055,649 | 5,060,731 | 5,062,315 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116R | D116R | 1 | 1 | 0 | 0 | 116 | D | R | 7 | CONSERVATION | null | false | false | null | null | 5,442,157 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.544073 | 0.095019 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876996,"numValue":-0.54407250479452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876997,"numValue":0.0950192698602466,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462015 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,015 | train | mutant | 5,055,650 | 5,060,731 | 5,062,316 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116S | D116S | 1 | 1 | 0 | 0 | 116 | D | S | 7 | CONSERVATION | null | false | false | null | null | 5,442,158 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.592017 | 0.107984 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876998,"numValue":-0.59201671517718,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876999,"numValue":0.107984130797219,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462016 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,016 | train | mutant | 5,055,651 | 5,060,731 | 5,062,317 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116T | D116T | 1 | 1 | 0 | 0 | 116 | D | T | 7 | CONSERVATION | null | false | false | null | null | 5,442,159 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.906648 | 0.24613 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877000,"numValue":-0.906648206334752,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877001,"numValue":0.246130473194982,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462018 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,018 | train | mutant | 5,055,653 | 5,060,731 | 5,062,319 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116W | D116W | 1 | 1 | 0 | 0 | 116 | D | W | 7 | CONSERVATION | null | false | false | null | null | 5,442,161 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.581604 | 0.130628 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877004,"numValue":-0.581603759957159,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877005,"numValue":0.130628407341462,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462019 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,019 | train | mutant | 5,055,654 | 5,060,731 | 5,062,320 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D116Y | D116Y | 1 | 1 | 0 | 0 | 116 | D | Y | 7 | CONSERVATION | null | false | false | null | null | 5,442,162 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.793641 | 0.197317 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12877006,"numValue":-0.793640507169633,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12877007,"numValue":0.197317048060125,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462349,"numValue":7.0,"position":116,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462020 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,020 | train | mutant | 5,054,082 | 5,060,731 | 5,060,748 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delQ117 | delQ117 | 1 | 0 | 1 | 0 | 117 | Q | - | 5 | CONSERVATION | null | false | false | null | null | 5,440,586 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.719473 | 0.30606 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873854,"numValue":-0.719473261223327,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873855,"numValue":0.306060321166998,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462021 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,021 | train | mutant | 5,054,083 | 5,060,731 | 5,060,749 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117A | Q117A | 1 | 1 | 0 | 0 | 117 | Q | A | 5 | CONSERVATION | null | false | false | null | null | 5,440,587 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.357782 | 0.063937 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873856,"numValue":-0.357782493597331,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873857,"numValue":0.0639365742665761,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462022 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,022 | train | mutant | 5,054,084 | 5,060,731 | 5,060,750 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117C | Q117C | 1 | 1 | 0 | 0 | 117 | Q | C | 5 | CONSERVATION | null | false | false | null | null | 5,440,588 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.429544 | 0.143126 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873858,"numValue":-0.429543660658918,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873859,"numValue":0.143126098868868,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462023 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,023 | train | mutant | 5,054,085 | 5,060,731 | 5,060,751 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117D | Q117D | 1 | 1 | 0 | 0 | 117 | Q | D | 5 | CONSERVATION | null | false | false | null | null | 5,440,589 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.431674 | 0.244907 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873860,"numValue":-0.431673664577536,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873861,"numValue":0.244906906902114,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462025 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,025 | train | mutant | 5,054,087 | 5,060,731 | 5,060,753 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117F | Q117F | 1 | 1 | 0 | 0 | 117 | Q | F | 5 | CONSERVATION | null | false | false | null | null | 5,440,591 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.33959 | 0.233214 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873864,"numValue":-0.339589574722285,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873865,"numValue":0.233213625295592,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462026 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,026 | train | mutant | 5,054,088 | 5,060,731 | 5,060,754 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117G | Q117G | 1 | 1 | 0 | 0 | 117 | Q | G | 5 | CONSERVATION | null | false | false | null | null | 5,440,592 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.684508 | 0.080518 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873866,"numValue":-0.684507511215146,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873867,"numValue":0.0805176724850019,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462027 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,027 | train | mutant | 5,054,089 | 5,060,731 | 5,060,755 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117H | Q117H | 1 | 1 | 0 | 0 | 117 | Q | H | 5 | CONSERVATION | null | false | false | null | null | 5,440,593 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.315066 | 0.144257 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873868,"numValue":-0.315066468846993,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873869,"numValue":0.144256895289918,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462028 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,028 | train | mutant | 5,054,090 | 5,060,731 | 5,060,756 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117I | Q117I | 1 | 1 | 0 | 0 | 117 | Q | I | 5 | CONSERVATION | null | false | false | null | null | 5,440,594 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.015464 | 0.121911 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873870,"numValue":-0.0154644120118788,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873871,"numValue":0.121911104052457,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462029 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,029 | train | mutant | 5,054,091 | 5,060,731 | 5,060,757 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117K | Q117K | 1 | 1 | 0 | 0 | 117 | Q | K | 5 | CONSERVATION | null | false | false | null | null | 5,440,595 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.111216 | 0.07356 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873872,"numValue":-0.111215944542388,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873873,"numValue":0.073560059792832,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462030 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,030 | train | mutant | 5,054,092 | 5,060,731 | 5,060,758 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117L | Q117L | 1 | 1 | 0 | 0 | 117 | Q | L | 5 | CONSERVATION | null | false | false | null | null | 5,440,596 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.352433 | 0.058813 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873874,"numValue":-0.352433189969936,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873875,"numValue":0.0588133979998292,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462031 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,031 | train | mutant | 5,054,093 | 5,060,731 | 5,060,759 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117M | Q117M | 1 | 1 | 0 | 0 | 117 | Q | M | 5 | CONSERVATION | null | false | false | null | null | 5,440,597 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.161419 | 0.078688 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873876,"numValue":-0.161418938493671,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873877,"numValue":0.0786876223570283,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462032 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,032 | train | mutant | 5,054,094 | 5,060,731 | 5,060,760 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117N | Q117N | 1 | 1 | 0 | 0 | 117 | Q | N | 5 | CONSERVATION | null | false | false | null | null | 5,440,598 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.102521 | 0.118654 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873878,"numValue":-0.102520604664192,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873879,"numValue":0.118653942998883,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462033 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,033 | train | mutant | 5,054,095 | 5,060,731 | 5,060,761 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117P | Q117P | 1 | 1 | 0 | 0 | 117 | Q | P | 5 | CONSERVATION | null | false | false | null | null | 5,440,599 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.027485 | 0.181326 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873880,"numValue":-1.02748538898462,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873881,"numValue":0.181325769577324,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462034 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,034 | train | mutant | 5,055,632 | 5,060,731 | 5,062,298 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117R | Q117R | 1 | 1 | 0 | 0 | 117 | Q | R | 5 | CONSERVATION | null | false | false | null | null | 5,442,140 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.190112 | 0.043261 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876962,"numValue":-0.190112474690601,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876963,"numValue":0.0432606024135809,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462036 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,036 | train | mutant | 5,055,634 | 5,060,731 | 5,062,300 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117T | Q117T | 1 | 1 | 0 | 0 | 117 | Q | T | 5 | CONSERVATION | null | false | false | null | null | 5,442,142 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.117247 | 0.070195 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876966,"numValue":0.117246943917484,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876967,"numValue":0.0701951247931952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462037 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,037 | train | mutant | 5,055,635 | 5,060,731 | 5,062,301 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117V | Q117V | 1 | 1 | 0 | 0 | 117 | Q | V | 5 | CONSERVATION | null | false | false | null | null | 5,442,143 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.164752 | 0.062501 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876968,"numValue":-0.164751758389712,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876969,"numValue":0.0625008184403265,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462038 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,038 | train | mutant | 5,055,636 | 5,060,731 | 5,062,302 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117W | Q117W | 1 | 1 | 0 | 0 | 117 | Q | W | 5 | CONSERVATION | null | false | false | null | null | 5,442,144 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.801732 | 0.154486 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876970,"numValue":-0.801732108639075,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876971,"numValue":0.154486290027159,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462039 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,039 | train | mutant | 5,055,637 | 5,060,731 | 5,062,303 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q117Y | Q117Y | 1 | 1 | 0 | 0 | 117 | Q | Y | 5 | CONSERVATION | null | false | false | null | null | 5,442,145 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.744782 | 0.640673 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876972,"numValue":-0.744782197506291,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876973,"numValue":0.640673331774399,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462350,"numValue":5.0,"position":117,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462040 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,040 | train | mutant | 5,054,096 | 5,060,731 | 5,060,762 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delH118 | delH118 | 1 | 0 | 1 | 0 | 118 | H | - | 9 | CONSERVATION | null | false | false | null | null | 5,440,600 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.973924 | 0.305564 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873882,"numValue":-0.973923525510518,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873883,"numValue":0.305564292857183,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462351,"numValue":9.0,"position":118,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462041 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,041 | train | mutant | 5,054,097 | 5,060,731 | 5,060,763 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | H118A | H118A | 1 | 1 | 0 | 0 | 118 | H | A | 9 | CONSERVATION | null | false | false | null | null | 5,440,601 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.276483 | 0.080381 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873884,"numValue":-0.276482949226372,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873885,"numValue":0.0803814227214358,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462351,"numValue":9.0,"position":118,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462043 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,043 | train | mutant | 5,054,099 | 5,060,731 | 5,060,765 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | H118D | H118D | 1 | 1 | 0 | 0 | 118 | H | D | 9 | CONSERVATION | null | false | false | null | null | 5,440,603 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.750949 | 0.236594 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873888,"numValue":-0.750948935867958,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873889,"numValue":0.236593755910847,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462351,"numValue":9.0,"position":118,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462044 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,044 | train | mutant | 5,054,100 | 5,060,731 | 5,060,766 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | H118E | H118E | 1 | 1 | 0 | 0 | 118 | H | E | 9 | CONSERVATION | null | false | false | null | null | 5,440,604 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.440667 | 0.112196 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873890,"numValue":-0.440666915138393,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873891,"numValue":0.112195870208373,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462351,"numValue":9.0,"position":118,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462045 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,045 | train | mutant | 5,054,101 | 5,060,731 | 5,060,767 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | H118F | H118F | 1 | 1 | 0 | 0 | 118 | H | F | 9 | CONSERVATION | null | false | false | null | null | 5,440,605 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.553449 | 0.125006 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873892,"numValue":-0.553449476573293,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873893,"numValue":0.125006284951313,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462351,"numValue":9.0,"position":118,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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