row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5462153 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,153 | train | mutant | 5,055,559 | 5,060,731 | 5,062,225 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I123Q | I123Q | 1 | 1 | 0 | 0 | 123 | I | Q | 9 | CONSERVATION | null | false | false | null | null | 5,442,067 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.654706 | 0.154776 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876816,"numValue":-0.654706227409092,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876817,"numValue":0.154775964430767,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462356,"numValue":9.0,"position":123,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462154 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,154 | train | mutant | 5,055,560 | 5,060,731 | 5,062,226 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I123R | I123R | 1 | 1 | 0 | 0 | 123 | I | R | 9 | CONSERVATION | null | false | false | null | null | 5,442,068 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.631039 | 0.063957 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876818,"numValue":-0.631039119931237,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876819,"numValue":0.0639574522762697,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462356,"numValue":9.0,"position":123,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462155 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,155 | train | mutant | 5,055,561 | 5,060,731 | 5,062,227 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I123S | I123S | 1 | 1 | 0 | 0 | 123 | I | S | 9 | CONSERVATION | null | false | false | null | null | 5,442,069 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.977443 | 0.149882 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876820,"numValue":-0.977443098245561,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876821,"numValue":0.149882401577662,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462356,"numValue":9.0,"position":123,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462156 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,156 | train | mutant | 5,055,562 | 5,060,731 | 5,062,228 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I123T | I123T | 1 | 1 | 0 | 0 | 123 | I | T | 9 | CONSERVATION | null | false | false | null | null | 5,442,070 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.51549 | 0.09192 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876822,"numValue":-0.515490062594125,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876823,"numValue":0.0919204496752975,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462356,"numValue":9.0,"position":123,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462158 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,158 | train | mutant | 5,055,564 | 5,060,731 | 5,062,230 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I123W | I123W | 1 | 1 | 0 | 0 | 123 | I | W | 9 | CONSERVATION | null | false | false | null | null | 5,442,072 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.793005 | 0.105723 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876826,"numValue":-0.793004717504407,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876827,"numValue":0.105722984884991,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462356,"numValue":9.0,"position":123,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462159 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,159 | train | mutant | 5,055,565 | 5,060,731 | 5,062,231 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | I123Y | I123Y | 1 | 1 | 0 | 0 | 123 | I | Y | 9 | CONSERVATION | null | false | false | null | null | 5,442,073 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.539845 | 0.202089 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876828,"numValue":-0.539844675908006,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876829,"numValue":0.202088918294037,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462356,"numValue":9.0,"position":123,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462160 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,160 | train | mutant | 5,054,137 | 5,060,731 | 5,060,803 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delA124 | delA124 | 1 | 0 | 1 | 0 | 124 | A | - | 6 | CONSERVATION | null | false | false | null | null | 5,440,642 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873966,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873967,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462161 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,161 | train | mutant | 5,055,535 | 5,060,731 | 5,062,201 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124C | A124C | 1 | 1 | 0 | 0 | 124 | A | C | 6 | CONSERVATION | null | false | false | null | null | 5,442,043 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876768,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876769,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462162 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,162 | train | mutant | 5,055,536 | 5,060,731 | 5,062,202 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124D | A124D | 1 | 1 | 0 | 0 | 124 | A | D | 6 | CONSERVATION | null | false | false | null | null | 5,442,044 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876770,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876771,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462163 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,163 | train | mutant | 5,055,537 | 5,060,731 | 5,062,203 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124E | A124E | 1 | 1 | 0 | 0 | 124 | A | E | 6 | CONSERVATION | null | false | false | null | null | 5,442,045 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.114979 | 0.412643 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876772,"numValue":-0.114979094057189,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876773,"numValue":0.412642752194146,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462164 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,164 | train | mutant | 5,055,538 | 5,060,731 | 5,062,204 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124F | A124F | 1 | 1 | 0 | 0 | 124 | A | F | 6 | CONSERVATION | null | false | false | null | null | 5,442,046 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876774,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876775,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462165 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,165 | train | mutant | 5,055,539 | 5,060,731 | 5,062,205 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124G | A124G | 1 | 1 | 0 | 0 | 124 | A | G | 6 | CONSERVATION | null | false | false | null | null | 5,442,047 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876776,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876777,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462166 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,166 | train | mutant | 5,055,540 | 5,060,731 | 5,062,206 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124H | A124H | 1 | 1 | 0 | 0 | 124 | A | H | 6 | CONSERVATION | null | false | false | null | null | 5,442,048 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876778,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876779,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462167 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,167 | train | mutant | 5,055,541 | 5,060,731 | 5,062,207 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124I | A124I | 1 | 1 | 0 | 0 | 124 | A | I | 6 | CONSERVATION | null | false | false | null | null | 5,442,049 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876780,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876781,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462168 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,168 | train | mutant | 5,055,542 | 5,060,731 | 5,062,208 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124K | A124K | 1 | 1 | 0 | 0 | 124 | A | K | 6 | CONSERVATION | null | false | false | null | null | 5,442,050 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876782,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876783,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462169 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,169 | train | mutant | 5,055,543 | 5,060,731 | 5,062,209 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124L | A124L | 1 | 1 | 0 | 0 | 124 | A | L | 6 | CONSERVATION | null | false | false | null | null | 5,442,051 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876784,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876785,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462170 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,170 | train | mutant | 5,055,544 | 5,060,731 | 5,062,210 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124M | A124M | 1 | 1 | 0 | 0 | 124 | A | M | 6 | CONSERVATION | null | false | false | null | null | 5,442,052 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876786,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876787,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462171 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,171 | train | mutant | 5,055,545 | 5,060,731 | 5,062,211 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124N | A124N | 1 | 1 | 0 | 0 | 124 | A | N | 6 | CONSERVATION | null | false | false | null | null | 5,442,053 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876788,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876789,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462172 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,172 | train | mutant | 5,055,546 | 5,060,731 | 5,062,212 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124P | A124P | 1 | 1 | 0 | 0 | 124 | A | P | 6 | CONSERVATION | null | false | false | null | null | 5,442,054 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876790,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876791,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462173 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,173 | train | mutant | 5,055,547 | 5,060,731 | 5,062,213 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124Q | A124Q | 1 | 1 | 0 | 0 | 124 | A | Q | 6 | CONSERVATION | null | false | false | null | null | 5,442,055 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.745736 | 0.67235 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876792,"numValue":-0.74573575430988,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876793,"numValue":0.67234980562541,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462174 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,174 | train | mutant | 5,055,548 | 5,060,731 | 5,062,214 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124R | A124R | 1 | 1 | 0 | 0 | 124 | A | R | 6 | CONSERVATION | null | false | false | null | null | 5,442,056 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.038029 | 0.453511 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876794,"numValue":-0.0380292627333113,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876795,"numValue":0.45351148809291,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462176 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,176 | train | mutant | 5,055,550 | 5,060,731 | 5,062,216 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124T | A124T | 1 | 1 | 0 | 0 | 124 | A | T | 6 | CONSERVATION | null | false | false | null | null | 5,442,058 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876798,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876799,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462178 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,178 | train | mutant | 5,055,552 | 5,060,731 | 5,062,218 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A124W | A124W | 1 | 1 | 0 | 0 | 124 | A | W | 6 | CONSERVATION | null | false | false | null | null | 5,442,060 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876802,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876803,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462357,"numValue":6.0,"position":124,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462180 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,180 | train | mutant | 5,054,138 | 5,060,731 | 5,060,804 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delR125 | delR125 | 1 | 0 | 1 | 0 | 125 | R | - | 8 | CONSERVATION | null | false | false | null | null | 5,440,643 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.635082 | 0.159502 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873968,"numValue":-0.635081600615486,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873969,"numValue":0.159501737040829,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462181 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,181 | train | mutant | 5,054,139 | 5,060,731 | 5,060,805 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125A | R125A | 1 | 1 | 0 | 0 | 125 | R | A | 8 | CONSERVATION | null | false | false | null | null | 5,440,644 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.707057 | 0.091768 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873970,"numValue":-0.707056655543965,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873971,"numValue":0.0917684296719934,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462182 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,182 | train | mutant | 5,054,140 | 5,060,731 | 5,060,806 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125C | R125C | 1 | 1 | 0 | 0 | 125 | R | C | 8 | CONSERVATION | null | false | false | null | null | 5,440,645 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.361435 | 0.153314 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873972,"numValue":-0.361435315281091,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873973,"numValue":0.153313865280971,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462183 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,183 | train | mutant | 5,054,141 | 5,060,731 | 5,060,807 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125D | R125D | 1 | 1 | 0 | 0 | 125 | R | D | 8 | CONSERVATION | null | false | false | null | null | 5,440,646 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.665799 | 0.261222 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873974,"numValue":-0.665798771421708,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873975,"numValue":0.261221826458727,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462184 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,184 | train | mutant | 5,054,142 | 5,060,731 | 5,060,808 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125E | R125E | 1 | 1 | 0 | 0 | 125 | R | E | 8 | CONSERVATION | null | false | false | null | null | 5,440,647 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.31568 | 0.070241 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873976,"numValue":-0.315679975865787,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873977,"numValue":0.0702407754871735,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462185 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,185 | train | mutant | 5,054,143 | 5,060,731 | 5,060,809 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125F | R125F | 1 | 1 | 0 | 0 | 125 | R | F | 8 | CONSERVATION | null | false | false | null | null | 5,440,648 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.654825 | 0.208926 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873978,"numValue":-0.654825493837555,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873979,"numValue":0.208926243003752,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462186 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,186 | train | mutant | 5,054,144 | 5,060,731 | 5,060,810 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125G | R125G | 1 | 1 | 0 | 0 | 125 | R | G | 8 | CONSERVATION | null | false | false | null | null | 5,440,649 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.169502 | 0.033795 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873980,"numValue":-0.169501984448437,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873981,"numValue":0.0337953747546874,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462187 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,187 | train | mutant | 5,054,145 | 5,060,731 | 5,060,811 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125H | R125H | 1 | 1 | 0 | 0 | 125 | R | H | 8 | CONSERVATION | null | false | false | null | null | 5,440,650 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.218834 | 0.116378 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873982,"numValue":-0.218834103622287,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873983,"numValue":0.116377665318162,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462188 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,188 | train | mutant | 5,054,146 | 5,060,731 | 5,060,812 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125I | R125I | 1 | 1 | 0 | 0 | 125 | R | I | 8 | CONSERVATION | null | false | false | null | null | 5,440,651 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.80294 | 0.377856 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873984,"numValue":-0.802940287774952,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873985,"numValue":0.377855837981537,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462189 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,189 | train | mutant | 5,054,147 | 5,060,731 | 5,060,813 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125K | R125K | 1 | 1 | 0 | 0 | 125 | R | K | 8 | CONSERVATION | null | false | false | null | null | 5,440,652 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.228059 | 0.094805 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873986,"numValue":-0.228058736162133,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873987,"numValue":0.0948048073692351,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462190 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,190 | train | mutant | 5,054,148 | 5,060,731 | 5,060,814 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125L | R125L | 1 | 1 | 0 | 0 | 125 | R | L | 8 | CONSERVATION | null | false | false | null | null | 5,440,653 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.948452 | 0.128453 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873988,"numValue":-0.948451593903557,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873989,"numValue":0.12845281657599,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462191 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,191 | train | mutant | 5,054,149 | 5,060,731 | 5,060,815 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125M | R125M | 1 | 1 | 0 | 0 | 125 | R | M | 8 | CONSERVATION | null | false | false | null | null | 5,440,654 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.628348 | 0.106932 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873990,"numValue":-0.628348474412866,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873991,"numValue":0.106931930186362,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462192 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,192 | train | mutant | 5,054,150 | 5,060,731 | 5,060,816 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125N | R125N | 1 | 1 | 0 | 0 | 125 | R | N | 8 | CONSERVATION | null | false | false | null | null | 5,440,655 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.139894 | 0.162267 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873992,"numValue":-0.139893518958207,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873993,"numValue":0.162266956000552,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462193 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,193 | train | mutant | 5,054,151 | 5,060,731 | 5,060,817 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125P | R125P | 1 | 1 | 0 | 0 | 125 | R | P | 8 | CONSERVATION | null | false | false | null | null | 5,440,656 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.963644 | 0.180384 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873994,"numValue":-0.963643691544965,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873995,"numValue":0.180383577561886,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462194 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,194 | train | mutant | 5,054,152 | 5,060,731 | 5,060,818 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125Q | R125Q | 1 | 1 | 0 | 0 | 125 | R | Q | 8 | CONSERVATION | null | false | false | null | null | 5,440,657 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.152233 | 0.091117 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873996,"numValue":-0.152233252699736,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873997,"numValue":0.0911165505314076,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462195 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,195 | train | mutant | 5,055,530 | 5,060,731 | 5,062,196 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125S | R125S | 1 | 1 | 0 | 0 | 125 | R | S | 8 | CONSERVATION | null | false | false | null | null | 5,442,038 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.461877 | 0.085432 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876758,"numValue":-0.461876993726222,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876759,"numValue":0.0854317941121778,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462196 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,196 | train | mutant | 5,055,531 | 5,060,731 | 5,062,197 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125T | R125T | 1 | 1 | 0 | 0 | 125 | R | T | 8 | CONSERVATION | null | false | false | null | null | 5,442,039 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.745588 | 0.127836 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876760,"numValue":-0.745587820522541,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876761,"numValue":0.127835606423978,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462198 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,198 | train | mutant | 5,055,533 | 5,060,731 | 5,062,199 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125W | R125W | 1 | 1 | 0 | 0 | 125 | R | W | 8 | CONSERVATION | null | false | false | null | null | 5,442,041 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.182059 | 0.292554 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876764,"numValue":-1.18205908572514,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876765,"numValue":0.292553781226232,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462199 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,199 | train | mutant | 5,055,534 | 5,060,731 | 5,062,200 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R125Y | R125Y | 1 | 1 | 0 | 0 | 125 | R | Y | 8 | CONSERVATION | null | false | false | null | null | 5,442,042 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.484338 | 0.129773 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876766,"numValue":-0.484338412106053,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876767,"numValue":0.129773366650891,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462358,"numValue":8.0,"position":125,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462200 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,200 | train | mutant | 5,054,153 | 5,060,731 | 5,060,819 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delV126 | delV126 | 1 | 0 | 1 | 0 | 126 | V | - | 8 | CONSERVATION | null | false | false | null | null | 5,440,658 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.63669 | 0.129515 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12873998,"numValue":-0.636690165068759,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12873999,"numValue":0.129515232726759,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462201 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,201 | train | mutant | 5,054,154 | 5,060,731 | 5,060,820 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126A | V126A | 1 | 1 | 0 | 0 | 126 | V | A | 8 | CONSERVATION | null | false | false | null | null | 5,440,659 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.039126 | 0.061239 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874000,"numValue":-0.0391255178600359,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874001,"numValue":0.0612385863288941,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462202 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,202 | train | mutant | 5,054,155 | 5,060,731 | 5,060,821 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126C | V126C | 1 | 1 | 0 | 0 | 126 | V | C | 8 | CONSERVATION | null | false | false | null | null | 5,440,660 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.022922 | 0.068436 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874002,"numValue":0.0229223946183258,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874003,"numValue":0.0684363919032269,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462203 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,203 | train | mutant | 5,054,156 | 5,060,731 | 5,060,822 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126D | V126D | 1 | 1 | 0 | 0 | 126 | V | D | 8 | CONSERVATION | null | false | false | null | null | 5,440,661 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.688399 | 0.142843 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874004,"numValue":-0.688398929602959,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874005,"numValue":0.142842681483456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462204 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,204 | train | mutant | 5,054,157 | 5,060,731 | 5,060,823 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126E | V126E | 1 | 1 | 0 | 0 | 126 | V | E | 8 | CONSERVATION | null | false | false | null | null | 5,440,662 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.538413 | 0.108747 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874006,"numValue":-0.538413159530819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874007,"numValue":0.10874710393434,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462205 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,205 | train | mutant | 5,054,158 | 5,060,731 | 5,060,824 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126F | V126F | 1 | 1 | 0 | 0 | 126 | V | F | 8 | CONSERVATION | null | false | false | null | null | 5,440,663 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.494788 | 0.151734 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874008,"numValue":-0.494788462505377,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874009,"numValue":0.15173447896357,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462206 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,206 | train | mutant | 5,054,159 | 5,060,731 | 5,060,825 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126G | V126G | 1 | 1 | 0 | 0 | 126 | V | G | 8 | CONSERVATION | null | false | false | null | null | 5,440,664 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.597761 | 0.041961 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874010,"numValue":-0.597760977116393,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874011,"numValue":0.041961377278245,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462207 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,207 | train | mutant | 5,054,160 | 5,060,731 | 5,060,826 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126H | V126H | 1 | 1 | 0 | 0 | 126 | V | H | 8 | CONSERVATION | null | false | false | null | null | 5,440,665 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.878256 | 0.256718 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874012,"numValue":-0.878256475495074,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874013,"numValue":0.256717858758988,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462209 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,209 | train | mutant | 5,054,162 | 5,060,731 | 5,060,828 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126K | V126K | 1 | 1 | 0 | 0 | 126 | V | K | 8 | CONSERVATION | null | false | false | null | null | 5,440,667 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.89917 | 0.204324 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874016,"numValue":-0.899169652184809,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874017,"numValue":0.204323759190993,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462210 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,210 | train | mutant | 5,054,163 | 5,060,731 | 5,060,829 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126L | V126L | 1 | 1 | 0 | 0 | 126 | V | L | 8 | CONSERVATION | null | false | false | null | null | 5,440,668 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.632291 | 0.076423 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874018,"numValue":-0.632291225888732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874019,"numValue":0.0764230287000805,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462211 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,211 | train | mutant | 5,054,164 | 5,060,731 | 5,060,830 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126M | V126M | 1 | 1 | 0 | 0 | 126 | V | M | 8 | CONSERVATION | null | false | false | null | null | 5,440,669 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.610935 | 0.107072 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874020,"numValue":-0.61093474584455,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874021,"numValue":0.107071691541772,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462212 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,212 | train | mutant | 5,054,165 | 5,060,731 | 5,060,831 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126N | V126N | 1 | 1 | 0 | 0 | 126 | V | N | 8 | CONSERVATION | null | false | false | null | null | 5,440,670 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.860851 | 0.251735 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874022,"numValue":-0.860850746971452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874023,"numValue":0.251734718390286,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462213 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,213 | train | mutant | 5,054,166 | 5,060,731 | 5,060,832 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126P | V126P | 1 | 1 | 0 | 0 | 126 | V | P | 8 | CONSERVATION | null | false | false | null | null | 5,440,671 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.39635 | 0.119397 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874024,"numValue":-0.396350242978213,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874025,"numValue":0.119396931986053,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462214 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,214 | train | mutant | 5,054,167 | 5,060,731 | 5,060,833 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126Q | V126Q | 1 | 1 | 0 | 0 | 126 | V | Q | 8 | CONSERVATION | null | false | false | null | null | 5,440,672 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.774722 | 0.136212 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874026,"numValue":-0.774722476502263,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874027,"numValue":0.136212157609819,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462215 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,215 | train | mutant | 5,054,168 | 5,060,731 | 5,060,834 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126R | V126R | 1 | 1 | 0 | 0 | 126 | V | R | 8 | CONSERVATION | null | false | false | null | null | 5,440,673 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.851281 | 0.084643 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874028,"numValue":-0.851280733411919,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874029,"numValue":0.0846425159597859,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462216 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,216 | train | mutant | 5,054,169 | 5,060,731 | 5,060,835 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126S | V126S | 1 | 1 | 0 | 0 | 126 | V | S | 8 | CONSERVATION | null | false | false | null | null | 5,440,674 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.535125 | 0.067444 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874030,"numValue":-0.535125160316139,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874031,"numValue":0.0674440798950992,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462218 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,218 | train | mutant | 5,055,528 | 5,060,731 | 5,062,194 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126W | V126W | 1 | 1 | 0 | 0 | 126 | V | W | 8 | CONSERVATION | null | false | false | null | null | 5,442,036 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.892987 | 0.119127 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876754,"numValue":-0.892986946934261,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876755,"numValue":0.119127369426645,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462219 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,219 | train | mutant | 5,055,529 | 5,060,731 | 5,062,195 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V126Y | V126Y | 1 | 1 | 0 | 0 | 126 | V | Y | 8 | CONSERVATION | null | false | false | null | null | 5,442,037 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.729249 | 0.242686 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876756,"numValue":-0.729249341377007,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876757,"numValue":0.242686431608157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462359,"numValue":8.0,"position":126,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462220 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,220 | train | mutant | 5,054,171 | 5,060,731 | 5,060,837 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delT127 | delT127 | 1 | 0 | 1 | 0 | 127 | T | - | 6 | CONSERVATION | null | false | false | null | null | 5,440,676 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.144328 | 0.58267 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874034,"numValue":-1.14432824445149,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874035,"numValue":0.582669687699772,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462221 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,221 | train | mutant | 5,054,172 | 5,060,731 | 5,060,838 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127A | T127A | 1 | 1 | 0 | 0 | 127 | T | A | 6 | CONSERVATION | null | false | false | null | null | 5,440,677 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.399789 | 0.067318 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874036,"numValue":-0.399789496030704,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874037,"numValue":0.0673180456714443,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462222 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,222 | train | mutant | 5,054,173 | 5,060,731 | 5,060,839 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127C | T127C | 1 | 1 | 0 | 0 | 127 | T | C | 6 | CONSERVATION | null | false | false | null | null | 5,440,678 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.655587 | 0.175929 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874038,"numValue":-0.655586679255191,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874039,"numValue":0.175928580606596,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462223 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,223 | train | mutant | 5,054,174 | 5,060,731 | 5,060,840 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127D | T127D | 1 | 1 | 0 | 0 | 127 | T | D | 6 | CONSERVATION | null | false | false | null | null | 5,440,679 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.057693 | 0.0983 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874040,"numValue":-0.0576929001199527,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874041,"numValue":0.0982997989613669,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462224 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,224 | train | mutant | 5,054,175 | 5,060,731 | 5,060,841 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127E | T127E | 1 | 1 | 0 | 0 | 127 | T | E | 6 | CONSERVATION | null | false | false | null | null | 5,440,680 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.004093 | 0.077705 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874042,"numValue":-0.00409323914818362,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874043,"numValue":0.0777054620416874,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462225 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,225 | train | mutant | 5,054,176 | 5,060,731 | 5,060,842 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127F | T127F | 1 | 1 | 0 | 0 | 127 | T | F | 6 | CONSERVATION | null | false | false | null | null | 5,440,681 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.749109 | 0.170656 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874044,"numValue":-0.749108925588571,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874045,"numValue":0.170656212764157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462226 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,226 | train | mutant | 5,054,177 | 5,060,731 | 5,060,843 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127G | T127G | 1 | 1 | 0 | 0 | 127 | T | G | 6 | CONSERVATION | null | false | false | null | null | 5,440,682 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.264702 | 0.05752 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874046,"numValue":-0.264701941670863,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874047,"numValue":0.0575202064177533,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462227 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,227 | train | mutant | 5,054,178 | 5,060,731 | 5,060,844 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127H | T127H | 1 | 1 | 0 | 0 | 127 | T | H | 6 | CONSERVATION | null | false | false | null | null | 5,440,683 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.643837 | 0.221004 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874048,"numValue":-0.643837403720532,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874049,"numValue":0.221004075840807,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462228 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,228 | train | mutant | 5,054,179 | 5,060,731 | 5,060,845 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127I | T127I | 1 | 1 | 0 | 0 | 127 | T | I | 6 | CONSERVATION | null | false | false | null | null | 5,440,684 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.541278 | 0.168548 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874050,"numValue":-0.541278107698926,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874051,"numValue":0.168548236103474,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462229 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,229 | train | mutant | 5,054,180 | 5,060,731 | 5,060,846 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127K | T127K | 1 | 1 | 0 | 0 | 127 | T | K | 6 | CONSERVATION | null | false | false | null | null | 5,440,685 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.294617 | 0.165875 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874052,"numValue":-0.294617256441177,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874053,"numValue":0.165874573920205,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462230 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,230 | train | mutant | 5,054,181 | 5,060,731 | 5,060,847 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127L | T127L | 1 | 1 | 0 | 0 | 127 | T | L | 6 | CONSERVATION | null | false | false | null | null | 5,440,686 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.571033 | 0.08968 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874054,"numValue":-0.571033230034007,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874055,"numValue":0.0896796709957677,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462231 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,231 | train | mutant | 5,054,182 | 5,060,731 | 5,060,848 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127M | T127M | 1 | 1 | 0 | 0 | 127 | T | M | 6 | CONSERVATION | null | false | false | null | null | 5,440,687 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.606947 | 0.185957 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874056,"numValue":-0.606946790604576,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874057,"numValue":0.185956984596083,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462232 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,232 | train | mutant | 5,054,183 | 5,060,731 | 5,060,849 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127N | T127N | 1 | 1 | 0 | 0 | 127 | T | N | 6 | CONSERVATION | null | false | false | null | null | 5,440,688 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.20645 | 0.154069 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874058,"numValue":-0.20645031536489,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874059,"numValue":0.154068665986163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462233 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,233 | train | mutant | 5,054,184 | 5,060,731 | 5,060,850 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127P | T127P | 1 | 1 | 0 | 0 | 127 | T | P | 6 | CONSERVATION | null | false | false | null | null | 5,440,689 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.815455 | 0.129326 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874060,"numValue":-0.815455473414456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874061,"numValue":0.129326117544152,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462234 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,234 | train | mutant | 5,054,185 | 5,060,731 | 5,060,851 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127Q | T127Q | 1 | 1 | 0 | 0 | 127 | T | Q | 6 | CONSERVATION | null | false | false | null | null | 5,440,690 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.251608 | 0.118845 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874062,"numValue":-0.251608109542511,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874063,"numValue":0.118845037442348,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462235 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,235 | train | mutant | 5,054,186 | 5,060,731 | 5,060,852 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127R | T127R | 1 | 1 | 0 | 0 | 127 | T | R | 6 | CONSERVATION | null | false | false | null | null | 5,440,691 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.208703 | 0.052861 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874064,"numValue":-0.208702841915318,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874065,"numValue":0.0528614030565215,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462236 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,236 | train | mutant | 5,054,187 | 5,060,731 | 5,060,853 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127S | T127S | 1 | 1 | 0 | 0 | 127 | T | S | 6 | CONSERVATION | null | false | false | null | null | 5,440,692 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.044964 | 0.051903 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874066,"numValue":-0.0449643373905521,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874067,"numValue":0.0519028981007875,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462238 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,238 | train | mutant | 5,055,526 | 5,060,731 | 5,062,192 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127W | T127W | 1 | 1 | 0 | 0 | 127 | T | W | 6 | CONSERVATION | null | false | false | null | null | 5,442,034 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.864003 | 0.161842 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876750,"numValue":-0.864003262588059,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876751,"numValue":0.161841606457498,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462239 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,239 | train | mutant | 5,055,527 | 5,060,731 | 5,062,193 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T127Y | T127Y | 1 | 1 | 0 | 0 | 127 | T | Y | 6 | CONSERVATION | null | false | false | null | null | 5,442,035 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.53984 | 0.174786 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876752,"numValue":-0.539840398150668,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876753,"numValue":0.174785525537653,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462360,"numValue":6.0,"position":127,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462241 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,241 | train | mutant | 5,054,189 | 5,060,731 | 5,060,855 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128A | N128A | 1 | 1 | 0 | 0 | 128 | N | A | 4 | CONSERVATION | null | false | false | null | null | 5,440,694 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.717576 | 0.076791 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874070,"numValue":-0.717575916226188,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874071,"numValue":0.0767911712196317,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462242 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,242 | train | mutant | 5,054,190 | 5,060,731 | 5,060,856 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128C | N128C | 1 | 1 | 0 | 0 | 128 | N | C | 4 | CONSERVATION | null | false | false | null | null | 5,440,695 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.718396 | 0.141196 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874072,"numValue":-0.718395713304065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874073,"numValue":0.141196127991138,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462243 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,243 | train | mutant | 5,054,191 | 5,060,731 | 5,060,857 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128D | N128D | 1 | 1 | 0 | 0 | 128 | N | D | 4 | CONSERVATION | null | false | false | null | null | 5,440,696 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.142354 | 0.068469 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874074,"numValue":-0.142353548663081,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874075,"numValue":0.0684688900895695,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462244 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,244 | train | mutant | 5,054,192 | 5,060,731 | 5,060,858 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128E | N128E | 1 | 1 | 0 | 0 | 128 | N | E | 4 | CONSERVATION | null | false | false | null | null | 5,440,697 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.187866 | 0.063874 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874076,"numValue":-0.187866332852618,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874077,"numValue":0.0638740679317442,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462245 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,245 | train | mutant | 5,054,193 | 5,060,731 | 5,060,859 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128F | N128F | 1 | 1 | 0 | 0 | 128 | N | F | 4 | CONSERVATION | null | false | false | null | null | 5,440,698 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.996833 | 0.303482 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874078,"numValue":-0.996832831468332,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874079,"numValue":0.303482238129024,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462246 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,246 | train | mutant | 5,054,194 | 5,060,731 | 5,060,860 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128G | N128G | 1 | 1 | 0 | 0 | 128 | N | G | 4 | CONSERVATION | null | false | false | null | null | 5,440,699 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.604407 | 0.057897 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874080,"numValue":-0.604406888147021,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874081,"numValue":0.0578969746838171,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462247 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,247 | train | mutant | 5,054,195 | 5,060,731 | 5,060,861 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128H | N128H | 1 | 1 | 0 | 0 | 128 | N | H | 4 | CONSERVATION | null | false | false | null | null | 5,440,700 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.291067 | 0.107428 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874082,"numValue":-0.291066973239276,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874083,"numValue":0.107427830801928,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462248 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,248 | train | mutant | 5,054,196 | 5,060,731 | 5,060,862 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128I | N128I | 1 | 1 | 0 | 0 | 128 | N | I | 4 | CONSERVATION | null | false | false | null | null | 5,440,701 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.856892 | 0.245991 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874084,"numValue":-0.856891644247015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874085,"numValue":0.245990584145322,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462249 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,249 | train | mutant | 5,054,197 | 5,060,731 | 5,060,863 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128K | N128K | 1 | 1 | 0 | 0 | 128 | N | K | 4 | CONSERVATION | null | false | false | null | null | 5,440,702 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.04089 | 0.09039 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874086,"numValue":-0.0408902523797021,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874087,"numValue":0.0903895871724742,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462250 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,250 | train | mutant | 5,054,198 | 5,060,731 | 5,060,864 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128L | N128L | 1 | 1 | 0 | 0 | 128 | N | L | 4 | CONSERVATION | null | false | false | null | null | 5,440,703 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.795898 | 0.145556 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874088,"numValue":-0.795898205337141,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874089,"numValue":0.145556184272378,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462251 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,251 | train | mutant | 5,054,199 | 5,060,731 | 5,060,865 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128M | N128M | 1 | 1 | 0 | 0 | 128 | N | M | 4 | CONSERVATION | null | false | false | null | null | 5,440,704 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.847169 | 0.172711 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874090,"numValue":-0.84716935529568,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874091,"numValue":0.172711068617303,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462252 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,252 | train | mutant | 5,055,517 | 5,060,731 | 5,062,183 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128P | N128P | 1 | 1 | 0 | 0 | 128 | N | P | 4 | CONSERVATION | null | false | false | null | null | 5,442,025 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.806473 | 0.142074 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876732,"numValue":-0.80647256608776,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876733,"numValue":0.142073515175264,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462254 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,254 | train | mutant | 5,055,519 | 5,060,731 | 5,062,185 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128R | N128R | 1 | 1 | 0 | 0 | 128 | N | R | 4 | CONSERVATION | null | false | false | null | null | 5,442,027 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.35871 | 0.060361 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876736,"numValue":-0.35871019231552,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876737,"numValue":0.0603613268390167,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462256 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,256 | train | mutant | 5,055,521 | 5,060,731 | 5,062,187 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128T | N128T | 1 | 1 | 0 | 0 | 128 | N | T | 4 | CONSERVATION | null | false | false | null | null | 5,442,029 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.51848 | 0.098639 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876740,"numValue":-0.51847995958477,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876741,"numValue":0.0986388910392955,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462257 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,257 | train | mutant | 5,055,522 | 5,060,731 | 5,062,188 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128V | N128V | 1 | 1 | 0 | 0 | 128 | N | V | 4 | CONSERVATION | null | false | false | null | null | 5,442,030 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.94746 | 0.137343 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876742,"numValue":-0.947459837365412,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876743,"numValue":0.137342698642371,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462258 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,258 | train | mutant | 5,055,523 | 5,060,731 | 5,062,189 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128W | N128W | 1 | 1 | 0 | 0 | 128 | N | W | 4 | CONSERVATION | null | false | false | null | null | 5,442,031 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.604704 | 0.173918 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876744,"numValue":-0.604704415746936,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876745,"numValue":0.17391752388082,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462259 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,259 | train | mutant | 5,055,524 | 5,060,731 | 5,062,190 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | N128Y | N128Y | 1 | 1 | 0 | 0 | 128 | N | Y | 4 | CONSERVATION | null | false | false | null | null | 5,442,032 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.555316 | 0.204974 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876746,"numValue":-0.555316366492071,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876747,"numValue":0.204973531376472,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462361,"numValue":4.0,"position":128,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462260 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,260 | train | mutant | 5,054,200 | 5,060,731 | 5,060,866 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delV129 | delV129 | 1 | 0 | 1 | 0 | 129 | V | - | 9 | CONSERVATION | null | false | false | null | null | 5,440,705 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.93043 | 0.231171 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874092,"numValue":-0.930430436562694,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874093,"numValue":0.231171347325963,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462362,"numValue":9.0,"position":129,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462261 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,261 | train | mutant | 5,054,201 | 5,060,731 | 5,060,867 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V129A | V129A | 1 | 1 | 0 | 0 | 129 | V | A | 9 | CONSERVATION | null | false | false | null | null | 5,440,706 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.7944 | 0.101098 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874094,"numValue":-0.794400479491905,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874095,"numValue":0.101098154578677,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462362,"numValue":9.0,"position":129,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462262 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,262 | train | mutant | 5,054,202 | 5,060,731 | 5,060,868 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V129C | V129C | 1 | 1 | 0 | 0 | 129 | V | C | 9 | CONSERVATION | null | false | false | null | null | 5,440,707 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.342377 | 0.158726 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874096,"numValue":-0.342376820939941,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874097,"numValue":0.158725547548949,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462362,"numValue":9.0,"position":129,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462263 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,263 | train | mutant | 5,054,203 | 5,060,731 | 5,060,869 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V129D | V129D | 1 | 1 | 0 | 0 | 129 | V | D | 9 | CONSERVATION | null | false | false | null | null | 5,440,708 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.772644 | 0.111657 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874098,"numValue":-0.772643997213073,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874099,"numValue":0.111656681242433,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462362,"numValue":9.0,"position":129,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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