row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5462486 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,486 | train | mutant | 5,054,315 | 5,060,731 | 5,060,981 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140G | V140G | 1 | 1 | 0 | 0 | 140 | V | G | 8 | CONSERVATION | null | false | false | null | null | 5,440,821 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.418968 | 0.047774 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874324,"numValue":-0.418967703730188,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874325,"numValue":0.0477738662546399,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462487 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,487 | train | mutant | 5,054,316 | 5,060,731 | 5,060,982 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140H | V140H | 1 | 1 | 0 | 0 | 140 | V | H | 8 | CONSERVATION | null | false | false | null | null | 5,440,822 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.764207 | 0.257343 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874326,"numValue":-0.764206791259009,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874327,"numValue":0.257342794413057,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462488 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,488 | train | mutant | 5,054,317 | 5,060,731 | 5,060,983 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140I | V140I | 1 | 1 | 0 | 0 | 140 | V | I | 8 | CONSERVATION | null | false | false | null | null | 5,440,823 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.391512 | 0.118965 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874328,"numValue":-0.391512482511874,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874329,"numValue":0.118964942342056,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462489 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,489 | train | mutant | 5,054,318 | 5,060,731 | 5,060,984 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140K | V140K | 1 | 1 | 0 | 0 | 140 | V | K | 8 | CONSERVATION | null | false | false | null | null | 5,440,824 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.092117 | 0.296705 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874330,"numValue":-1.09211732228352,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874331,"numValue":0.296704738174914,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462490 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,490 | train | mutant | 5,054,319 | 5,060,731 | 5,060,985 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140L | V140L | 1 | 1 | 0 | 0 | 140 | V | L | 8 | CONSERVATION | null | false | false | null | null | 5,440,825 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.650001 | 0.07107 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874332,"numValue":-0.650000630490354,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874333,"numValue":0.0710703411750904,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462491 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,491 | train | mutant | 5,054,320 | 5,060,731 | 5,060,986 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140M | V140M | 1 | 1 | 0 | 0 | 140 | V | M | 8 | CONSERVATION | null | false | false | null | null | 5,440,826 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.721627 | 0.185332 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874334,"numValue":-0.721626633189491,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874335,"numValue":0.185331729706391,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462492 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,492 | train | mutant | 5,054,321 | 5,060,731 | 5,060,987 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140N | V140N | 1 | 1 | 0 | 0 | 140 | V | N | 8 | CONSERVATION | null | false | false | null | null | 5,440,827 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874336,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874337,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462494 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,494 | train | mutant | 5,054,323 | 5,060,731 | 5,060,989 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140Q | V140Q | 1 | 1 | 0 | 0 | 140 | V | Q | 8 | CONSERVATION | null | false | false | null | null | 5,440,829 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.612539 | 0.150534 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874340,"numValue":-0.61253909638761,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874341,"numValue":0.150534280718248,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462495 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,495 | train | mutant | 5,054,324 | 5,060,731 | 5,060,990 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140R | V140R | 1 | 1 | 0 | 0 | 140 | V | R | 8 | CONSERVATION | null | false | false | null | null | 5,440,830 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.909081 | 0.095904 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874342,"numValue":-0.909080749852553,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874343,"numValue":0.0959039356165597,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462496 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,496 | train | mutant | 5,054,325 | 5,060,731 | 5,060,991 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140S | V140S | 1 | 1 | 0 | 0 | 140 | V | S | 8 | CONSERVATION | null | false | false | null | null | 5,440,831 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.582919 | 0.074114 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874344,"numValue":-0.582919457650601,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874345,"numValue":0.0741135505146477,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462497 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,497 | train | mutant | 5,054,326 | 5,060,731 | 5,060,992 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140T | V140T | 1 | 1 | 0 | 0 | 140 | V | T | 8 | CONSERVATION | null | false | false | null | null | 5,440,832 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.675268 | 0.100817 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874346,"numValue":-0.675268385378051,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874347,"numValue":0.10081697184262,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462498 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,498 | train | mutant | 5,055,405 | 5,060,731 | 5,062,071 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V140W | V140W | 1 | 1 | 0 | 0 | 140 | V | W | 8 | CONSERVATION | null | false | false | null | null | 5,441,913 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.733691 | 0.128125 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876508,"numValue":-0.733690547353417,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876509,"numValue":0.12812547236896,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462373,"numValue":8.0,"position":140,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462500 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,500 | train | mutant | 5,054,327 | 5,060,731 | 5,060,993 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delL141 | delL141 | 1 | 0 | 1 | 0 | 141 | L | - | 8 | CONSERVATION | null | false | false | null | null | 5,440,833 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.756217 | 0.16125 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874348,"numValue":-0.75621677056456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874349,"numValue":0.16125044593226,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462501 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,501 | train | mutant | 5,054,328 | 5,060,731 | 5,060,994 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141A | L141A | 1 | 1 | 0 | 0 | 141 | L | A | 8 | CONSERVATION | null | false | false | null | null | 5,440,834 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.732074 | 0.087629 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874350,"numValue":-0.732074385092335,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874351,"numValue":0.0876288375114626,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462503 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,503 | train | mutant | 5,054,330 | 5,060,731 | 5,060,996 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141D | L141D | 1 | 1 | 0 | 0 | 141 | L | D | 8 | CONSERVATION | null | false | false | null | null | 5,440,836 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.93546 | 0.210512 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874354,"numValue":-0.935460370488901,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874355,"numValue":0.210511950186474,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462504 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,504 | train | mutant | 5,054,331 | 5,060,731 | 5,060,997 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141E | L141E | 1 | 1 | 0 | 0 | 141 | L | E | 8 | CONSERVATION | null | false | false | null | null | 5,440,837 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.817296 | 0.115252 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874356,"numValue":-0.817295739082341,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874357,"numValue":0.115251529737197,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462505 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,505 | train | mutant | 5,054,332 | 5,060,731 | 5,060,998 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141F | L141F | 1 | 1 | 0 | 0 | 141 | L | F | 8 | CONSERVATION | null | false | false | null | null | 5,440,838 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.895576 | 0.229551 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874358,"numValue":-0.89557634049033,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874359,"numValue":0.229550907307543,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462507 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,507 | train | mutant | 5,054,334 | 5,060,731 | 5,061,000 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141H | L141H | 1 | 1 | 0 | 0 | 141 | L | H | 8 | CONSERVATION | null | false | false | null | null | 5,440,840 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874362,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874363,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462508 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,508 | train | mutant | 5,054,335 | 5,060,731 | 5,061,001 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141I | L141I | 1 | 1 | 0 | 0 | 141 | L | I | 8 | CONSERVATION | null | false | false | null | null | 5,440,841 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.119118 | 0.068327 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874364,"numValue":-0.119118303134974,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874365,"numValue":0.0683271494733011,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462509 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,509 | train | mutant | 5,054,336 | 5,060,731 | 5,061,002 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141K | L141K | 1 | 1 | 0 | 0 | 141 | L | K | 8 | CONSERVATION | null | false | false | null | null | 5,440,842 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.807472 | 0.241811 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874366,"numValue":-0.807471518196829,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874367,"numValue":0.24181147061476,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462510 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,510 | train | mutant | 5,055,395 | 5,060,731 | 5,062,061 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141M | L141M | 1 | 1 | 0 | 0 | 141 | L | M | 8 | CONSERVATION | null | false | false | null | null | 5,441,903 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.766736 | 0.148741 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876488,"numValue":-0.766735520469787,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876489,"numValue":0.148741198075328,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462511 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,511 | train | mutant | 5,055,396 | 5,060,731 | 5,062,062 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141N | L141N | 1 | 1 | 0 | 0 | 141 | L | N | 8 | CONSERVATION | null | false | false | null | null | 5,441,904 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.804927 | 0.307099 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876490,"numValue":-0.804926507969318,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876491,"numValue":0.307099177728846,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462512 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,512 | train | mutant | 5,055,397 | 5,060,731 | 5,062,063 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141P | L141P | 1 | 1 | 0 | 0 | 141 | L | P | 8 | CONSERVATION | null | false | false | null | null | 5,441,905 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.878164 | 0.135535 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876492,"numValue":-0.878164490942886,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876493,"numValue":0.135534867313704,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462513 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,513 | train | mutant | 5,055,398 | 5,060,731 | 5,062,064 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141Q | L141Q | 1 | 1 | 0 | 0 | 141 | L | Q | 8 | CONSERVATION | null | false | false | null | null | 5,441,906 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.931139 | 0.230188 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876494,"numValue":-0.931139407801959,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876495,"numValue":0.230187590832511,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462514 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,514 | train | mutant | 5,055,399 | 5,060,731 | 5,062,065 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141R | L141R | 1 | 1 | 0 | 0 | 141 | L | R | 8 | CONSERVATION | null | false | false | null | null | 5,441,907 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.87131 | 0.083955 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876496,"numValue":-0.87130950611855,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876497,"numValue":0.0839546908881375,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462515 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,515 | train | mutant | 5,055,400 | 5,060,731 | 5,062,066 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141S | L141S | 1 | 1 | 0 | 0 | 141 | L | S | 8 | CONSERVATION | null | false | false | null | null | 5,441,908 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.812206 | 0.091319 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876498,"numValue":-0.812206101710065,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876499,"numValue":0.0913192651515212,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462517 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,517 | train | mutant | 5,055,402 | 5,060,731 | 5,062,068 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141V | L141V | 1 | 1 | 0 | 0 | 141 | L | V | 8 | CONSERVATION | null | false | false | null | null | 5,441,910 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.733918 | 0.077938 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876502,"numValue":-0.733918034657815,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876503,"numValue":0.0779383763516636,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462518 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,518 | train | mutant | 5,055,403 | 5,060,731 | 5,062,069 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141W | L141W | 1 | 1 | 0 | 0 | 141 | L | W | 8 | CONSERVATION | null | false | false | null | null | 5,441,911 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.797941 | 0.059779 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876504,"numValue":-0.797940547153895,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876505,"numValue":0.0597792453748744,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462519 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,519 | train | mutant | 5,055,404 | 5,060,731 | 5,062,070 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | L141Y | L141Y | 1 | 1 | 0 | 0 | 141 | L | Y | 8 | CONSERVATION | null | false | false | null | null | 5,441,912 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.78315 | 0.253631 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876506,"numValue":-0.783149849999162,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876507,"numValue":0.253631424916181,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462374,"numValue":8.0,"position":141,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462520 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,520 | train | mutant | 5,054,337 | 5,060,731 | 5,061,003 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delT142 | delT142 | 1 | 0 | 1 | 0 | 142 | T | - | 5 | CONSERVATION | null | false | false | null | null | 5,440,843 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874368,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874369,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462521 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,521 | train | mutant | 5,054,338 | 5,060,731 | 5,061,004 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142A | T142A | 1 | 1 | 0 | 0 | 142 | T | A | 5 | CONSERVATION | null | false | false | null | null | 5,440,844 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.585325 | 0.360761 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874370,"numValue":-0.585325472688195,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874371,"numValue":0.360761025799825,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462522 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,522 | train | mutant | 5,054,339 | 5,060,731 | 5,061,005 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142C | T142C | 1 | 1 | 0 | 0 | 142 | T | C | 5 | CONSERVATION | null | false | false | null | null | 5,440,845 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874372,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874373,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462523 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,523 | train | mutant | 5,054,340 | 5,060,731 | 5,061,006 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142D | T142D | 1 | 1 | 0 | 0 | 142 | T | D | 5 | CONSERVATION | null | false | false | null | null | 5,440,846 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.6257 | 0.391647 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874374,"numValue":-0.625699584913882,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874375,"numValue":0.391646625320333,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462524 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,524 | train | mutant | 5,054,341 | 5,060,731 | 5,061,007 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142E | T142E | 1 | 1 | 0 | 0 | 142 | T | E | 5 | CONSERVATION | null | false | false | null | null | 5,440,847 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.394914 | 0.787855 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874376,"numValue":-0.394913682678195,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874377,"numValue":0.787854999988029,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462525 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,525 | train | mutant | 5,054,342 | 5,060,731 | 5,061,008 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142F | T142F | 1 | 1 | 0 | 0 | 142 | T | F | 5 | CONSERVATION | null | false | false | null | null | 5,440,848 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874378,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874379,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462526 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,526 | train | mutant | 5,054,343 | 5,060,731 | 5,061,009 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142G | T142G | 1 | 1 | 0 | 0 | 142 | T | G | 5 | CONSERVATION | null | false | false | null | null | 5,440,849 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874380,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874381,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462528 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,528 | train | mutant | 5,054,345 | 5,060,731 | 5,061,011 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142I | T142I | 1 | 1 | 0 | 0 | 142 | T | I | 5 | CONSERVATION | null | false | false | null | null | 5,440,851 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.825456 | 0.283692 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874384,"numValue":-0.825455976210561,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874385,"numValue":0.283692055741732,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462529 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,529 | train | mutant | 5,054,346 | 5,060,731 | 5,061,012 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142K | T142K | 1 | 1 | 0 | 0 | 142 | T | K | 5 | CONSERVATION | null | false | false | null | null | 5,440,852 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874386,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874387,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462530 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,530 | train | mutant | 5,054,347 | 5,060,731 | 5,061,013 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142L | T142L | 1 | 1 | 0 | 0 | 142 | T | L | 5 | CONSERVATION | null | false | false | null | null | 5,440,853 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874388,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874389,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462531 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,531 | train | mutant | 5,054,348 | 5,060,731 | 5,061,014 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142M | T142M | 1 | 1 | 0 | 0 | 142 | T | M | 5 | CONSERVATION | null | false | false | null | null | 5,440,854 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874390,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874391,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462532 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,532 | train | mutant | 5,054,349 | 5,060,731 | 5,061,015 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142N | T142N | 1 | 1 | 0 | 0 | 142 | T | N | 5 | CONSERVATION | null | false | false | null | null | 5,440,855 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.33796 | 0.208921 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874392,"numValue":-0.337960387647816,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874393,"numValue":0.208921007539547,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462533 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,533 | train | mutant | 5,054,350 | 5,060,731 | 5,061,016 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142P | T142P | 1 | 1 | 0 | 0 | 142 | T | P | 5 | CONSERVATION | null | false | false | null | null | 5,440,856 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874394,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874395,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462534 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,534 | train | mutant | 5,054,351 | 5,060,731 | 5,061,017 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142Q | T142Q | 1 | 1 | 0 | 0 | 142 | T | Q | 5 | CONSERVATION | null | false | false | null | null | 5,440,857 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874396,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874397,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462535 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,535 | train | mutant | 5,054,352 | 5,060,731 | 5,061,018 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142R | T142R | 1 | 1 | 0 | 0 | 142 | T | R | 5 | CONSERVATION | null | false | false | null | null | 5,440,858 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874398,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874399,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462536 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,536 | train | mutant | 5,054,353 | 5,060,731 | 5,061,019 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142S | T142S | 1 | 1 | 0 | 0 | 142 | T | S | 5 | CONSERVATION | null | false | false | null | null | 5,440,859 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.2083 | 0.351475 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874400,"numValue":-0.208299966560069,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874401,"numValue":0.35147522771476,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462537 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,537 | train | mutant | 5,055,392 | 5,060,731 | 5,062,058 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142V | T142V | 1 | 1 | 0 | 0 | 142 | T | V | 5 | CONSERVATION | null | false | false | null | null | 5,441,900 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876482,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876483,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462538 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,538 | train | mutant | 5,055,393 | 5,060,731 | 5,062,059 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142W | T142W | 1 | 1 | 0 | 0 | 142 | T | W | 5 | CONSERVATION | null | false | false | null | null | 5,441,901 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876484,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876485,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462539 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,539 | train | mutant | 5,055,394 | 5,060,731 | 5,062,060 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | T142Y | T142Y | 1 | 1 | 0 | 0 | 142 | T | Y | 5 | CONSERVATION | null | false | false | null | null | 5,441,902 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876486,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876487,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462375,"numValue":5.0,"position":142,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462540 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,540 | train | mutant | 5,054,354 | 5,060,731 | 5,061,020 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delD143 | delD143 | 1 | 0 | 1 | 0 | 143 | D | - | 4 | CONSERVATION | null | false | false | null | null | 5,440,860 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.914062 | 0.358087 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874402,"numValue":-0.914062268504293,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874403,"numValue":0.35808698053381,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462541 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,541 | train | mutant | 5,054,355 | 5,060,731 | 5,061,021 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143A | D143A | 1 | 1 | 0 | 0 | 143 | D | A | 4 | CONSERVATION | null | false | false | null | null | 5,440,861 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.165364 | 0.059573 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874404,"numValue":-0.165364052313141,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874405,"numValue":0.0595731277030279,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462542 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,542 | train | mutant | 5,054,356 | 5,060,731 | 5,061,022 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143C | D143C | 1 | 1 | 0 | 0 | 143 | D | C | 4 | CONSERVATION | null | false | false | null | null | 5,440,862 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.53867 | 0.129142 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874406,"numValue":-0.538670463442334,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874407,"numValue":0.129142110131501,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462543 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,543 | train | mutant | 5,055,375 | 5,060,731 | 5,062,041 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143E | D143E | 1 | 1 | 0 | 0 | 143 | D | E | 4 | CONSERVATION | null | false | false | null | null | 5,441,883 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.013499 | 0.077288 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876448,"numValue":-0.0134985590502102,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876449,"numValue":0.0772875187650689,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462545 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,545 | train | mutant | 5,055,377 | 5,060,731 | 5,062,043 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143G | D143G | 1 | 1 | 0 | 0 | 143 | D | G | 4 | CONSERVATION | null | false | false | null | null | 5,441,885 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.545196 | 0.051824 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876452,"numValue":-0.545195831102009,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876453,"numValue":0.0518237532053252,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462546 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,546 | train | mutant | 5,055,378 | 5,060,731 | 5,062,044 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143H | D143H | 1 | 1 | 0 | 0 | 143 | D | H | 4 | CONSERVATION | null | false | false | null | null | 5,441,886 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.093922 | 0.136145 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876454,"numValue":0.0939216739439088,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876455,"numValue":0.136145054282027,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462547 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,547 | train | mutant | 5,055,379 | 5,060,731 | 5,062,045 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143I | D143I | 1 | 1 | 0 | 0 | 143 | D | I | 4 | CONSERVATION | null | false | false | null | null | 5,441,887 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.309492 | 0.141782 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876456,"numValue":-0.309492487188675,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876457,"numValue":0.141781542275176,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462548 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,548 | train | mutant | 5,055,380 | 5,060,731 | 5,062,046 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143K | D143K | 1 | 1 | 0 | 0 | 143 | D | K | 4 | CONSERVATION | null | false | false | null | null | 5,441,888 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.415772 | 0.118479 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876458,"numValue":-0.415772155151705,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876459,"numValue":0.118478682642281,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462549 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,549 | train | mutant | 5,055,381 | 5,060,731 | 5,062,047 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143L | D143L | 1 | 1 | 0 | 0 | 143 | D | L | 4 | CONSERVATION | null | false | false | null | null | 5,441,889 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.09724 | 0.047229 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876460,"numValue":-0.0972404474725717,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876461,"numValue":0.0472289693557745,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462551 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,551 | train | mutant | 5,055,383 | 5,060,731 | 5,062,049 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143N | D143N | 1 | 1 | 0 | 0 | 143 | D | N | 4 | CONSERVATION | null | false | false | null | null | 5,441,891 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.325072 | 0.083631 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876464,"numValue":-0.325071632483182,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876465,"numValue":0.0836311775085735,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462552 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,552 | train | mutant | 5,055,384 | 5,060,731 | 5,062,050 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143P | D143P | 1 | 1 | 0 | 0 | 143 | D | P | 4 | CONSERVATION | null | false | false | null | null | 5,441,892 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.213452 | 0.075282 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876466,"numValue":-0.213451791031554,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876467,"numValue":0.0752816975034976,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462553 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,553 | train | mutant | 5,055,385 | 5,060,731 | 5,062,051 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143Q | D143Q | 1 | 1 | 0 | 0 | 143 | D | Q | 4 | CONSERVATION | null | false | false | null | null | 5,441,893 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.199185 | 0.112709 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876468,"numValue":-0.199185151074268,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876469,"numValue":0.112709201088913,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462554 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,554 | train | mutant | 5,055,386 | 5,060,731 | 5,062,052 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143R | D143R | 1 | 1 | 0 | 0 | 143 | D | R | 4 | CONSERVATION | null | false | false | null | null | 5,441,894 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.254254 | 0.05334 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876470,"numValue":-0.254254062073771,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876471,"numValue":0.0533401862580238,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462555 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,555 | train | mutant | 5,055,387 | 5,060,731 | 5,062,053 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143S | D143S | 1 | 1 | 0 | 0 | 143 | D | S | 4 | CONSERVATION | null | false | false | null | null | 5,441,895 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.24862 | 0.057821 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876472,"numValue":-0.248620064118475,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876473,"numValue":0.0578211179152637,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462556 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,556 | train | mutant | 5,055,388 | 5,060,731 | 5,062,054 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143T | D143T | 1 | 1 | 0 | 0 | 143 | D | T | 4 | CONSERVATION | null | false | false | null | null | 5,441,896 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.193245 | 0.13173 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876474,"numValue":-0.193245453087128,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876475,"numValue":0.131729706391017,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462557 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,557 | train | mutant | 5,055,389 | 5,060,731 | 5,062,055 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143V | D143V | 1 | 1 | 0 | 0 | 143 | D | V | 4 | CONSERVATION | null | false | false | null | null | 5,441,897 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.339449 | 0.055152 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876476,"numValue":-0.339448919507132,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876477,"numValue":0.0551519378001314,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462558 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,558 | train | mutant | 5,055,390 | 5,060,731 | 5,062,056 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143W | D143W | 1 | 1 | 0 | 0 | 143 | D | W | 4 | CONSERVATION | null | false | false | null | null | 5,441,898 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.260436 | 0.073607 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876478,"numValue":-0.260436251439553,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876479,"numValue":0.0736070512764237,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462559 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,559 | train | mutant | 5,055,391 | 5,060,731 | 5,062,057 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | D143Y | D143Y | 1 | 1 | 0 | 0 | 143 | D | Y | 4 | CONSERVATION | null | false | false | null | null | 5,441,899 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.292522 | 0.112514 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876480,"numValue":-0.292521985358258,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876481,"numValue":0.112513892735235,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462376,"numValue":4.0,"position":143,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462560 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,560 | train | mutant | 5,054,357 | 5,060,731 | 5,061,023 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delE144 | delE144 | 1 | 0 | 1 | 0 | 144 | E | - | 8 | CONSERVATION | null | false | false | null | null | 5,440,863 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.657232 | 0.151271 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874408,"numValue":-0.657232275040643,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874409,"numValue":0.151271012687222,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462561 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,561 | train | mutant | 5,054,358 | 5,060,731 | 5,061,024 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144A | E144A | 1 | 1 | 0 | 0 | 144 | E | A | 8 | CONSERVATION | null | false | false | null | null | 5,440,864 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.251589 | 0.054392 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874410,"numValue":-0.251588955405178,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874411,"numValue":0.0543919782472847,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462562 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,562 | train | mutant | 5,054,359 | 5,060,731 | 5,061,025 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144C | E144C | 1 | 1 | 0 | 0 | 144 | E | C | 8 | CONSERVATION | null | false | false | null | null | 5,440,865 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.832002 | 0.210072 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874412,"numValue":-0.832001583408686,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874413,"numValue":0.210072043499046,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462563 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,563 | train | mutant | 5,054,360 | 5,060,731 | 5,061,026 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144D | E144D | 1 | 1 | 0 | 0 | 144 | E | D | 8 | CONSERVATION | null | false | false | null | null | 5,440,866 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.161343 | 0.115398 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874414,"numValue":-0.161342960415581,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874415,"numValue":0.115398378123421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462564 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,564 | train | mutant | 5,055,359 | 5,060,731 | 5,062,025 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144F | E144F | 1 | 1 | 0 | 0 | 144 | E | F | 8 | CONSERVATION | null | false | false | null | null | 5,441,867 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.820432 | 0.192479 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876416,"numValue":-0.820431845987966,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876417,"numValue":0.192478968358163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462565 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,565 | train | mutant | 5,055,360 | 5,060,731 | 5,062,026 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144G | E144G | 1 | 1 | 0 | 0 | 144 | E | G | 8 | CONSERVATION | null | false | false | null | null | 5,441,868 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.468691 | 0.048306 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876418,"numValue":-0.468690822694141,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876419,"numValue":0.0483056425694317,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462566 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,566 | train | mutant | 5,055,361 | 5,060,731 | 5,062,027 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144H | E144H | 1 | 1 | 0 | 0 | 144 | E | H | 8 | CONSERVATION | null | false | false | null | null | 5,441,869 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.823211 | 0.218326 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876420,"numValue":-0.823210983620818,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876421,"numValue":0.218325816664578,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462567 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,567 | train | mutant | 5,055,362 | 5,060,731 | 5,062,028 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144I | E144I | 1 | 1 | 0 | 0 | 144 | E | I | 8 | CONSERVATION | null | false | false | null | null | 5,441,870 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.58148 | 0.12298 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876422,"numValue":-0.58147983268861,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876423,"numValue":0.122979777221421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462568 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,568 | train | mutant | 5,055,363 | 5,060,731 | 5,062,029 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144K | E144K | 1 | 1 | 0 | 0 | 144 | E | K | 8 | CONSERVATION | null | false | false | null | null | 5,441,871 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.650314 | 0.214537 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876424,"numValue":-0.650314311412753,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876425,"numValue":0.214537319841372,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462569 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,569 | train | mutant | 5,055,364 | 5,060,731 | 5,062,030 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144L | E144L | 1 | 1 | 0 | 0 | 144 | E | L | 8 | CONSERVATION | null | false | false | null | null | 5,441,872 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.461226 | 0.071525 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876426,"numValue":-0.461225625362632,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876427,"numValue":0.0715251880896382,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462570 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,570 | train | mutant | 5,055,365 | 5,060,731 | 5,062,031 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144M | E144M | 1 | 1 | 0 | 0 | 144 | E | M | 8 | CONSERVATION | null | false | false | null | null | 5,441,873 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.693447 | 0.128172 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876428,"numValue":-0.693446810955847,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876429,"numValue":0.128171697687058,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462571 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,571 | train | mutant | 5,055,366 | 5,060,731 | 5,062,032 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144N | E144N | 1 | 1 | 0 | 0 | 144 | E | N | 8 | CONSERVATION | null | false | false | null | null | 5,441,874 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.326856 | 0.218969 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876430,"numValue":-0.326855521140182,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876431,"numValue":0.218968565666368,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462572 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,572 | train | mutant | 5,055,367 | 5,060,731 | 5,062,033 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144P | E144P | 1 | 1 | 0 | 0 | 144 | E | P | 8 | CONSERVATION | null | false | false | null | null | 5,441,875 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.735271 | 0.115299 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876432,"numValue":-0.735271402154681,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876433,"numValue":0.115299223539158,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462573 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,573 | train | mutant | 5,055,368 | 5,060,731 | 5,062,034 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144Q | E144Q | 1 | 1 | 0 | 0 | 144 | E | Q | 8 | CONSERVATION | null | false | false | null | null | 5,441,876 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.380418 | 0.115407 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876434,"numValue":-0.380418086932648,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876435,"numValue":0.115406614402475,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462574 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,574 | train | mutant | 5,055,369 | 5,060,731 | 5,062,035 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144R | E144R | 1 | 1 | 0 | 0 | 144 | E | R | 8 | CONSERVATION | null | false | false | null | null | 5,441,877 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.238429 | 0.051185 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876436,"numValue":-0.238429424585772,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876437,"numValue":0.0511845477189418,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462575 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,575 | train | mutant | 5,055,370 | 5,060,731 | 5,062,036 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144S | E144S | 1 | 1 | 0 | 0 | 144 | E | S | 8 | CONSERVATION | null | false | false | null | null | 5,441,878 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.263415 | 0.053196 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876438,"numValue":-0.263414975183421,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876439,"numValue":0.0531956810612669,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462576 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,576 | train | mutant | 5,055,371 | 5,060,731 | 5,062,037 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144T | E144T | 1 | 1 | 0 | 0 | 144 | E | T | 8 | CONSERVATION | null | false | false | null | null | 5,441,879 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.465015 | 0.09568 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876440,"numValue":-0.465014952198456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876441,"numValue":0.0956796406683836,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462578 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,578 | train | mutant | 5,055,373 | 5,060,731 | 5,062,039 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144W | E144W | 1 | 1 | 0 | 0 | 144 | E | W | 8 | CONSERVATION | null | false | false | null | null | 5,441,881 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.462936 | 0.104135 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876444,"numValue":-0.462936281367893,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876445,"numValue":0.104135170747163,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462579 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,579 | train | mutant | 5,055,374 | 5,060,731 | 5,062,040 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | E144Y | E144Y | 1 | 1 | 0 | 0 | 144 | E | Y | 8 | CONSERVATION | null | false | false | null | null | 5,441,882 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.477461 | 0.081332 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876446,"numValue":-0.477461310637809,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876447,"numValue":0.0813324894871719,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462377,"numValue":8.0,"position":144,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462580 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,580 | train | mutant | 5,054,361 | 5,060,731 | 5,061,027 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delQ145 | delQ145 | 1 | 0 | 1 | 0 | 145 | Q | - | 7 | CONSERVATION | null | false | false | null | null | 5,440,867 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.929399 | 0.436052 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874416,"numValue":-0.929398813880046,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874417,"numValue":0.43605159805362,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462581 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,581 | train | mutant | 5,054,362 | 5,060,731 | 5,061,028 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145A | Q145A | 1 | 1 | 0 | 0 | 145 | Q | A | 7 | CONSERVATION | null | false | false | null | null | 5,440,868 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.910626 | 0.102614 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874418,"numValue":-0.910626112037338,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874419,"numValue":0.102613693771633,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462582 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,582 | train | mutant | 5,054,363 | 5,060,731 | 5,061,029 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145C | Q145C | 1 | 1 | 0 | 0 | 145 | Q | C | 7 | CONSERVATION | null | false | false | null | null | 5,440,869 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.679903 | 0.215887 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874420,"numValue":-0.679902665058783,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874421,"numValue":0.215887367287766,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462583 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,583 | train | mutant | 5,054,364 | 5,060,731 | 5,061,030 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145D | Q145D | 1 | 1 | 0 | 0 | 145 | Q | D | 7 | CONSERVATION | null | false | false | null | null | 5,440,870 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.841909 | 0.270948 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874422,"numValue":-0.841908754478277,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874423,"numValue":0.270947595078344,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462584 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,584 | train | mutant | 5,054,365 | 5,060,731 | 5,061,031 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145E | Q145E | 1 | 1 | 0 | 0 | 145 | Q | E | 7 | CONSERVATION | null | false | false | null | null | 5,440,871 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.276283 | 0.106037 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874424,"numValue":-0.276283235421108,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874425,"numValue":0.106037112737262,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462585 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,585 | train | mutant | 5,054,366 | 5,060,731 | 5,061,032 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145F | Q145F | 1 | 1 | 0 | 0 | 145 | Q | F | 7 | CONSERVATION | null | false | false | null | null | 5,440,872 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.828839 | 0.26847 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874426,"numValue":-0.828838711788494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874427,"numValue":0.268469624331501,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462586 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,586 | train | mutant | 5,054,367 | 5,060,731 | 5,061,033 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145G | Q145G | 1 | 1 | 0 | 0 | 145 | Q | G | 7 | CONSERVATION | null | false | false | null | null | 5,440,873 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.725487 | 0.070445 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874428,"numValue":-0.725486638792076,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874429,"numValue":0.0704449585911494,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462588 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,588 | train | mutant | 5,054,369 | 5,060,731 | 5,061,035 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145I | Q145I | 1 | 1 | 0 | 0 | 145 | Q | I | 7 | CONSERVATION | null | false | false | null | null | 5,440,875 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.771652 | 0.260296 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874432,"numValue":-0.77165174905207,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874433,"numValue":0.2602955962244,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462589 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,589 | train | mutant | 5,054,370 | 5,060,731 | 5,061,036 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145K | Q145K | 1 | 1 | 0 | 0 | 145 | Q | K | 7 | CONSERVATION | null | false | false | null | null | 5,440,876 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874434,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874435,"numValue":null,"references":[],"strValue":"NA","type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462590 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,590 | train | mutant | 5,054,371 | 5,060,731 | 5,061,037 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145L | Q145L | 1 | 1 | 0 | 0 | 145 | Q | L | 7 | CONSERVATION | null | false | false | null | null | 5,440,877 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.95041 | 0.13225 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874436,"numValue":-0.950410072522352,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874437,"numValue":0.132250251996619,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462592 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,592 | train | mutant | 5,054,373 | 5,060,731 | 5,061,039 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145N | Q145N | 1 | 1 | 0 | 0 | 145 | Q | N | 7 | CONSERVATION | null | false | false | null | null | 5,440,879 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.873476 | 0.22417 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874440,"numValue":-0.873475845435689,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874441,"numValue":0.224170127047797,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462593 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,593 | train | mutant | 5,054,374 | 5,060,731 | 5,061,040 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145P | Q145P | 1 | 1 | 0 | 0 | 145 | Q | P | 7 | CONSERVATION | null | false | false | null | null | 5,440,880 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.941484 | 0.163857 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874442,"numValue":-0.941484353065021,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874443,"numValue":0.163857132481985,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462594 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,594 | train | mutant | 5,055,353 | 5,060,731 | 5,062,019 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145R | Q145R | 1 | 1 | 0 | 0 | 145 | Q | R | 7 | CONSERVATION | null | false | false | null | null | 5,441,861 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.916773 | 0.10939 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876404,"numValue":-0.916772796017216,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876405,"numValue":0.109389916783254,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462595 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,595 | train | mutant | 5,055,354 | 5,060,731 | 5,062,020 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145S | Q145S | 1 | 1 | 0 | 0 | 145 | Q | S | 7 | CONSERVATION | null | false | false | null | null | 5,441,862 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.598302 | 0.091439 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876406,"numValue":-0.598301506871946,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876407,"numValue":0.0914392338983538,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462596 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,596 | train | mutant | 5,055,355 | 5,060,731 | 5,062,021 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145T | Q145T | 1 | 1 | 0 | 0 | 145 | Q | T | 7 | CONSERVATION | null | false | false | null | null | 5,441,863 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.506625 | 0.124237 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876408,"numValue":-0.506625272447651,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876409,"numValue":0.124236735560374,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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