row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5462597 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,597 | train | mutant | 5,055,356 | 5,060,731 | 5,062,022 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145V | Q145V | 1 | 1 | 0 | 0 | 145 | Q | V | 7 | CONSERVATION | null | false | false | null | null | 5,441,864 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.861604 | 0.105793 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876410,"numValue":-0.861604321811854,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876411,"numValue":0.10579276979201,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462598 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,598 | train | mutant | 5,055,357 | 5,060,731 | 5,062,023 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145W | Q145W | 1 | 1 | 0 | 0 | 145 | Q | W | 7 | CONSERVATION | null | false | false | null | null | 5,441,865 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.872642 | 0.143843 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876412,"numValue":-0.872641733832512,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876413,"numValue":0.143842910535015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462599 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,599 | train | mutant | 5,055,358 | 5,060,731 | 5,062,024 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q145Y | Q145Y | 1 | 1 | 0 | 0 | 145 | Q | Y | 7 | CONSERVATION | null | false | false | null | null | 5,441,866 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.890639 | 0.141481 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876414,"numValue":-0.890639147066264,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876415,"numValue":0.141481077707537,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462378,"numValue":7.0,"position":145,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462600 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,600 | train | mutant | 5,054,375 | 5,060,731 | 5,061,041 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delY146 | delY146 | 1 | 0 | 1 | 0 | 146 | Y | - | 9 | CONSERVATION | null | false | false | null | null | 5,440,881 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.658684 | 0.293419 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874444,"numValue":-0.658684286344776,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874445,"numValue":0.293419484386585,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462601 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,601 | train | mutant | 5,054,376 | 5,060,731 | 5,061,042 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146A | Y146A | 1 | 1 | 0 | 0 | 146 | Y | A | 9 | CONSERVATION | null | false | false | null | null | 5,440,882 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.099647 | 0.060204 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874446,"numValue":-0.0996474840641568,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874447,"numValue":0.0602042246046067,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462602 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,602 | train | mutant | 5,054,377 | 5,060,731 | 5,061,043 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146C | Y146C | 1 | 1 | 0 | 0 | 146 | Y | C | 9 | CONSERVATION | null | false | false | null | null | 5,440,883 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.121481 | 0.060364 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874448,"numValue":0.121481285210691,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874449,"numValue":0.06036439150099,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462604 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,604 | train | mutant | 5,054,379 | 5,060,731 | 5,061,045 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146E | Y146E | 1 | 1 | 0 | 0 | 146 | Y | E | 9 | CONSERVATION | null | false | false | null | null | 5,440,885 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.58975 | 0.123096 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874452,"numValue":-0.589750461494996,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874453,"numValue":0.123095723599414,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462605 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,605 | train | mutant | 5,054,380 | 5,060,731 | 5,061,046 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146F | Y146F | 1 | 1 | 0 | 0 | 146 | Y | F | 9 | CONSERVATION | null | false | false | null | null | 5,440,886 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.277377 | 0.109081 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874454,"numValue":-0.277377383592726,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874455,"numValue":0.109080960548064,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462606 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,606 | train | mutant | 5,054,381 | 5,060,731 | 5,061,047 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146G | Y146G | 1 | 1 | 0 | 0 | 146 | Y | G | 9 | CONSERVATION | null | false | false | null | null | 5,440,887 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.690225 | 0.06197 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874456,"numValue":-0.69022463812647,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874457,"numValue":0.0619698912922897,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462608 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,608 | train | mutant | 5,054,383 | 5,060,731 | 5,061,049 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146I | Y146I | 1 | 1 | 0 | 0 | 146 | Y | I | 9 | CONSERVATION | null | false | false | null | null | 5,440,889 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.09715 | 0.142357 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874460,"numValue":-0.0971504230271039,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874461,"numValue":0.142357251796299,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462609 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,609 | train | mutant | 5,054,384 | 5,060,731 | 5,061,050 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146K | Y146K | 1 | 1 | 0 | 0 | 146 | Y | K | 9 | CONSERVATION | null | false | false | null | null | 5,440,890 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.342173 | 0.151183 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874462,"numValue":-0.342173404001459,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874463,"numValue":0.151183350585358,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462610 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,610 | train | mutant | 5,054,385 | 5,060,731 | 5,061,051 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146L | Y146L | 1 | 1 | 0 | 0 | 146 | Y | L | 9 | CONSERVATION | null | false | false | null | null | 5,440,891 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.204013 | 0.056895 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874464,"numValue":-0.204012632153572,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874465,"numValue":0.0568953920732199,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462611 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,611 | train | mutant | 5,054,386 | 5,060,731 | 5,061,052 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146M | Y146M | 1 | 1 | 0 | 0 | 146 | Y | M | 9 | CONSERVATION | null | false | false | null | null | 5,440,892 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.18869 | 0.109334 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874466,"numValue":-0.188689960757961,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874467,"numValue":0.109333859007991,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462613 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,613 | train | mutant | 5,054,388 | 5,060,731 | 5,061,054 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146P | Y146P | 1 | 1 | 0 | 0 | 146 | Y | P | 9 | CONSERVATION | null | false | false | null | null | 5,440,894 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.653772 | 0.133029 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874470,"numValue":-0.653772399366956,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874471,"numValue":0.133029378456224,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462614 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,614 | train | mutant | 5,054,389 | 5,060,731 | 5,061,055 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146Q | Y146Q | 1 | 1 | 0 | 0 | 146 | Y | Q | 9 | CONSERVATION | null | false | false | null | null | 5,440,895 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.546099 | 0.130942 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874472,"numValue":-0.546099076371536,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874473,"numValue":0.130941513639741,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462616 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,616 | train | mutant | 5,054,391 | 5,060,731 | 5,061,057 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146S | Y146S | 1 | 1 | 0 | 0 | 146 | Y | S | 9 | CONSERVATION | null | false | false | null | null | 5,440,897 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.376048 | 0.052757 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874476,"numValue":-0.376047942805746,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874477,"numValue":0.0527574471684997,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462617 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,617 | train | mutant | 5,054,392 | 5,060,731 | 5,061,058 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146T | Y146T | 1 | 1 | 0 | 0 | 146 | Y | T | 9 | CONSERVATION | null | false | false | null | null | 5,440,898 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.188163 | 0.086 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874478,"numValue":-0.188163221981288,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874479,"numValue":0.0859996504369937,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462618 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,618 | train | mutant | 5,054,393 | 5,060,731 | 5,061,059 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146V | Y146V | 1 | 1 | 0 | 0 | 146 | Y | V | 9 | CONSERVATION | null | false | false | null | null | 5,440,899 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.135911 | 0.046973 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874480,"numValue":0.135910735335313,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874481,"numValue":0.0469731594669723,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462619 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,619 | train | mutant | 5,054,394 | 5,060,731 | 5,061,060 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Y146W | Y146W | 1 | 1 | 0 | 0 | 146 | Y | W | 9 | CONSERVATION | null | false | false | null | null | 5,440,900 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.523583 | 0.105909 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874482,"numValue":-0.52358300485318,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874483,"numValue":0.105909290794123,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462379,"numValue":9.0,"position":146,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462620 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,620 | train | mutant | 5,054,395 | 5,060,731 | 5,061,061 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delQ147 | delQ147 | 1 | 0 | 1 | 0 | 147 | Q | - | 7 | CONSERVATION | null | false | false | null | null | 5,440,901 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.787315 | 0.220067 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874484,"numValue":-0.787315364092218,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874485,"numValue":0.220067055442449,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462622 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,622 | train | mutant | 5,054,397 | 5,060,731 | 5,061,063 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147C | Q147C | 1 | 1 | 0 | 0 | 147 | Q | C | 7 | CONSERVATION | null | false | false | null | null | 5,440,903 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.30008 | 0.10616 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874488,"numValue":-0.300080335644333,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874489,"numValue":0.106159571521948,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462623 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,623 | train | mutant | 5,054,398 | 5,060,731 | 5,061,064 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147D | Q147D | 1 | 1 | 0 | 0 | 147 | Q | D | 7 | CONSERVATION | null | false | false | null | null | 5,440,904 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.18459 | 0.213378 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874490,"numValue":-0.184590336897333,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874491,"numValue":0.21337804760282,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462624 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,624 | train | mutant | 5,054,399 | 5,060,731 | 5,061,065 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147E | Q147E | 1 | 1 | 0 | 0 | 147 | Q | E | 7 | CONSERVATION | null | false | false | null | null | 5,440,905 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.051823 | 0.080802 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874492,"numValue":-0.051823433969703,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874493,"numValue":0.0808019837301565,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462625 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,625 | train | mutant | 5,054,400 | 5,060,731 | 5,061,066 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147F | Q147F | 1 | 1 | 0 | 0 | 147 | Q | F | 7 | CONSERVATION | null | false | false | null | null | 5,440,906 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.433057 | 0.128611 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874494,"numValue":-0.433056784834392,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874495,"numValue":0.128610774361868,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462626 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,626 | train | mutant | 5,054,401 | 5,060,731 | 5,061,067 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147G | Q147G | 1 | 1 | 0 | 0 | 147 | Q | G | 7 | CONSERVATION | null | false | false | null | null | 5,440,907 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.598991 | 0.061482 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874496,"numValue":-0.598990928121705,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874497,"numValue":0.0614822014169273,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462627 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,627 | train | mutant | 5,054,402 | 5,060,731 | 5,061,068 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147H | Q147H | 1 | 1 | 0 | 0 | 147 | Q | H | 7 | CONSERVATION | null | false | false | null | null | 5,440,908 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.049589 | 0.095215 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874498,"numValue":0.0495894230853644,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874499,"numValue":0.0952151528380446,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462628 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,628 | train | mutant | 5,054,403 | 5,060,731 | 5,061,069 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147I | Q147I | 1 | 1 | 0 | 0 | 147 | Q | I | 7 | CONSERVATION | null | false | false | null | null | 5,440,909 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.809822 | 0.29049 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874500,"numValue":-0.809822241624654,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874501,"numValue":0.290490050622789,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462629 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,629 | train | mutant | 5,054,404 | 5,060,731 | 5,061,070 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147K | Q147K | 1 | 1 | 0 | 0 | 147 | Q | K | 7 | CONSERVATION | null | false | false | null | null | 5,440,910 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.142994 | 0.129983 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874502,"numValue":-0.142993935321267,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874503,"numValue":0.129982976760445,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462630 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,630 | train | mutant | 5,054,405 | 5,060,731 | 5,061,071 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147L | Q147L | 1 | 1 | 0 | 0 | 147 | Q | L | 7 | CONSERVATION | null | false | false | null | null | 5,440,911 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.295236 | 0.064326 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874504,"numValue":-0.295235871229927,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874505,"numValue":0.0643261694199409,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462631 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,631 | train | mutant | 5,054,406 | 5,060,731 | 5,061,072 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147M | Q147M | 1 | 1 | 0 | 0 | 147 | Q | M | 7 | CONSERVATION | null | false | false | null | null | 5,440,912 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.32863 | 0.096826 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874506,"numValue":-0.328630471199759,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874507,"numValue":0.096825632705051,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462632 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,632 | train | mutant | 5,054,407 | 5,060,731 | 5,061,073 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147N | Q147N | 1 | 1 | 0 | 0 | 147 | Q | N | 7 | CONSERVATION | null | false | false | null | null | 5,440,913 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.004262 | 0.120245 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874508,"numValue":-0.00426179555671891,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874509,"numValue":0.120244821798685,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462633 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,633 | train | mutant | 5,054,408 | 5,060,731 | 5,061,074 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147P | Q147P | 1 | 1 | 0 | 0 | 147 | Q | P | 7 | CONSERVATION | null | false | false | null | null | 5,440,914 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.817396 | 0.127043 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874510,"numValue":-0.817396489844716,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874511,"numValue":0.127043391303862,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462634 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,634 | train | mutant | 5,055,347 | 5,060,731 | 5,062,013 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147R | Q147R | 1 | 1 | 0 | 0 | 147 | Q | R | 7 | CONSERVATION | null | false | false | null | null | 5,441,855 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.002547 | 0.05182 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876392,"numValue":-0.00254686179412021,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876393,"numValue":0.051820375692442,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462635 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,635 | train | mutant | 5,055,348 | 5,060,731 | 5,062,014 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147S | Q147S | 1 | 1 | 0 | 0 | 147 | Q | S | 7 | CONSERVATION | null | false | false | null | null | 5,441,856 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.388344 | 0.080351 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876394,"numValue":-0.388344196655528,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876395,"numValue":0.080350903795951,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462636 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,636 | train | mutant | 5,055,349 | 5,060,731 | 5,062,015 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147T | Q147T | 1 | 1 | 0 | 0 | 147 | Q | T | 7 | CONSERVATION | null | false | false | null | null | 5,441,857 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.285498 | 0.111467 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876396,"numValue":-0.285497780115292,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876397,"numValue":0.111466799894333,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462637 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,637 | train | mutant | 5,055,350 | 5,060,731 | 5,062,016 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147V | Q147V | 1 | 1 | 0 | 0 | 147 | Q | V | 7 | CONSERVATION | null | false | false | null | null | 5,441,858 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.416995 | 0.059341 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876398,"numValue":-0.416994572196333,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876399,"numValue":0.0593410880986566,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462638 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,638 | train | mutant | 5,055,351 | 5,060,731 | 5,062,017 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147W | Q147W | 1 | 1 | 0 | 0 | 147 | Q | W | 7 | CONSERVATION | null | false | false | null | null | 5,441,859 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.122989 | 0.073062 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876400,"numValue":-0.122988715818843,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876401,"numValue":0.0730621160692837,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462639 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,639 | train | mutant | 5,055,352 | 5,060,731 | 5,062,018 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | Q147Y | Q147Y | 1 | 1 | 0 | 0 | 147 | Q | Y | 7 | CONSERVATION | null | false | false | null | null | 5,441,860 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.331968 | 0.21054 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876402,"numValue":-0.331967760394511,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876403,"numValue":0.210539851379856,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462380,"numValue":7.0,"position":147,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462640 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,640 | train | mutant | 5,054,409 | 5,060,731 | 5,061,075 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delA148 | delA148 | 1 | 0 | 1 | 0 | 148 | A | - | 5 | CONSERVATION | null | false | false | null | null | 5,440,915 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.155771 | 0.339683 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874512,"numValue":-1.15577054301181,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874513,"numValue":0.339683046912473,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462643 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,643 | train | mutant | 5,055,330 | 5,060,731 | 5,061,996 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148E | A148E | 1 | 1 | 0 | 0 | 148 | A | E | 5 | CONSERVATION | null | false | false | null | null | 5,441,838 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.064013 | 0.061088 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876358,"numValue":-0.064013126968786,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876359,"numValue":0.0610875176477442,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462644 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,644 | train | mutant | 5,055,331 | 5,060,731 | 5,061,997 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148F | A148F | 1 | 1 | 0 | 0 | 148 | A | F | 5 | CONSERVATION | null | false | false | null | null | 5,441,839 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.840236 | 0.172326 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876360,"numValue":-0.840236400362971,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876361,"numValue":0.172325559679902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462645 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,645 | train | mutant | 5,055,332 | 5,060,731 | 5,061,998 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148G | A148G | 1 | 1 | 0 | 0 | 148 | A | G | 5 | CONSERVATION | null | false | false | null | null | 5,441,840 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.472463 | 0.060729 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876362,"numValue":-0.472462783112116,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876363,"numValue":0.0607286904236496,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462647 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,647 | train | mutant | 5,055,334 | 5,060,731 | 5,062,000 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148I | A148I | 1 | 1 | 0 | 0 | 148 | A | I | 5 | CONSERVATION | null | false | false | null | null | 5,441,842 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.862409 | 0.437044 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876366,"numValue":-0.862409223355597,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876367,"numValue":0.437043846214624,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462648 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,648 | train | mutant | 5,055,335 | 5,060,731 | 5,062,001 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148K | A148K | 1 | 1 | 0 | 0 | 148 | A | K | 5 | CONSERVATION | null | false | false | null | null | 5,441,843 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.224475 | 0.142829 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876368,"numValue":-0.224474997067023,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876369,"numValue":0.142828826657451,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462649 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,649 | train | mutant | 5,055,336 | 5,060,731 | 5,062,002 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148L | A148L | 1 | 1 | 0 | 0 | 148 | A | L | 5 | CONSERVATION | null | false | false | null | null | 5,441,844 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.218011 | 0.054304 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876370,"numValue":-0.218011114188188,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876371,"numValue":0.0543043416842712,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462651 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,651 | train | mutant | 5,055,338 | 5,060,731 | 5,062,004 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148N | A148N | 1 | 1 | 0 | 0 | 148 | A | N | 5 | CONSERVATION | null | false | false | null | null | 5,441,846 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.85116 | 0.294041 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876374,"numValue":-0.851160260272803,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876375,"numValue":0.294040716907437,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462652 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,652 | train | mutant | 5,055,339 | 5,060,731 | 5,062,005 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148P | A148P | 1 | 1 | 0 | 0 | 148 | A | P | 5 | CONSERVATION | null | false | false | null | null | 5,441,847 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.663739 | 0.114972 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876376,"numValue":-0.663739127034229,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876377,"numValue":0.114972262414874,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462653 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,653 | train | mutant | 5,055,340 | 5,060,731 | 5,062,006 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148Q | A148Q | 1 | 1 | 0 | 0 | 148 | A | Q | 5 | CONSERVATION | null | false | false | null | null | 5,441,848 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.011146 | 0.075624 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876378,"numValue":-0.0111457925144034,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876379,"numValue":0.0756244288675196,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462654 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,654 | train | mutant | 5,055,341 | 5,060,731 | 5,062,007 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148R | A148R | 1 | 1 | 0 | 0 | 148 | A | R | 5 | CONSERVATION | null | false | false | null | null | 5,441,849 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.491403 | 0.058887 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876380,"numValue":-0.491403224120167,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876381,"numValue":0.0588869562719026,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462655 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,655 | train | mutant | 5,055,342 | 5,060,731 | 5,062,008 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148S | A148S | 1 | 1 | 0 | 0 | 148 | A | S | 5 | CONSERVATION | null | false | false | null | null | 5,441,850 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.079744 | 0.05221 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876382,"numValue":-0.0797444199608457,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876383,"numValue":0.0522104369298152,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462656 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,656 | train | mutant | 5,055,343 | 5,060,731 | 5,062,009 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148T | A148T | 1 | 1 | 0 | 0 | 148 | A | T | 5 | CONSERVATION | null | false | false | null | null | 5,441,851 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.347986 | 0.073981 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876384,"numValue":-0.347985982363828,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876385,"numValue":0.0739810677314239,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462657 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,657 | train | mutant | 5,055,344 | 5,060,731 | 5,062,010 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148V | A148V | 1 | 1 | 0 | 0 | 148 | A | V | 5 | CONSERVATION | null | false | false | null | null | 5,441,852 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.365205 | 0.050911 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876386,"numValue":-0.365205296438208,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876387,"numValue":0.0509110968696553,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462658 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,658 | train | mutant | 5,055,345 | 5,060,731 | 5,062,011 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A148W | A148W | 1 | 1 | 0 | 0 | 148 | A | W | 5 | CONSERVATION | null | false | false | null | null | 5,441,853 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.956586 | 0.169747 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876388,"numValue":-0.956586094255914,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876389,"numValue":0.169747157406306,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462381,"numValue":5.0,"position":148,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462660 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,660 | train | mutant | 5,054,410 | 5,060,731 | 5,061,076 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delV149 | delV149 | 1 | 0 | 1 | 0 | 149 | V | - | 9 | CONSERVATION | null | false | false | null | null | 5,440,916 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.853911 | 0.139579 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874514,"numValue":-0.853910781624478,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874515,"numValue":0.139578624940443,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462661 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,661 | train | mutant | 5,054,411 | 5,060,731 | 5,061,077 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149A | V149A | 1 | 1 | 0 | 0 | 149 | V | A | 9 | CONSERVATION | null | false | false | null | null | 5,440,917 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.45992 | 0.079911 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874516,"numValue":-0.459920462444722,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874517,"numValue":0.0799109971085233,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462662 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,662 | train | mutant | 5,054,412 | 5,060,731 | 5,061,078 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149C | V149C | 1 | 1 | 0 | 0 | 149 | V | C | 9 | CONSERVATION | null | false | false | null | null | 5,440,918 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.039885 | 0.068593 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874518,"numValue":0.0398846601696897,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874519,"numValue":0.0685934558293622,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462663 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,663 | train | mutant | 5,054,413 | 5,060,731 | 5,061,079 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149D | V149D | 1 | 1 | 0 | 0 | 149 | V | D | 9 | CONSERVATION | null | false | false | null | null | 5,440,919 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.790367 | 0.214984 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874520,"numValue":-0.790366937405077,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874521,"numValue":0.214984377406737,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462664 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,664 | train | mutant | 5,054,414 | 5,060,731 | 5,061,080 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149E | V149E | 1 | 1 | 0 | 0 | 149 | V | E | 9 | CONSERVATION | null | false | false | null | null | 5,440,920 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.800633 | 0.124348 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874522,"numValue":-0.80063298039175,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874523,"numValue":0.12434770186266,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462665 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,665 | train | mutant | 5,054,415 | 5,060,731 | 5,061,081 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149F | V149F | 1 | 1 | 0 | 0 | 149 | V | F | 9 | CONSERVATION | null | false | false | null | null | 5,440,921 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.547909 | 0.124523 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874524,"numValue":-0.547909461585181,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874525,"numValue":0.124522579136516,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462666 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,666 | train | mutant | 5,054,416 | 5,060,731 | 5,061,082 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149G | V149G | 1 | 1 | 0 | 0 | 149 | V | G | 9 | CONSERVATION | null | false | false | null | null | 5,440,922 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.691064 | 0.079573 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874526,"numValue":-0.691063717035929,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874527,"numValue":0.079573373514457,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462667 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,667 | train | mutant | 5,054,417 | 5,060,731 | 5,061,083 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149H | V149H | 1 | 1 | 0 | 0 | 149 | V | H | 9 | CONSERVATION | null | false | false | null | null | 5,440,923 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.81887 | 0.28216 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874528,"numValue":-0.818869762241289,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874529,"numValue":0.282159852449295,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462668 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,668 | train | mutant | 5,054,418 | 5,060,731 | 5,061,084 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149I | V149I | 1 | 1 | 0 | 0 | 149 | V | I | 9 | CONSERVATION | null | false | false | null | null | 5,440,924 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.143162 | 0.130886 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874530,"numValue":-0.143162491729802,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874531,"numValue":0.130886158182847,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462669 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,669 | train | mutant | 5,054,419 | 5,060,731 | 5,061,085 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149K | V149K | 1 | 1 | 0 | 0 | 149 | V | K | 9 | CONSERVATION | null | false | false | null | null | 5,440,925 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.325482 | 0.116869 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874532,"numValue":-0.325482297187614,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874533,"numValue":0.116868585858022,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462670 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,670 | train | mutant | 5,054,420 | 5,060,731 | 5,061,086 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149L | V149L | 1 | 1 | 0 | 0 | 149 | V | L | 9 | CONSERVATION | null | false | false | null | null | 5,440,926 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.846487 | 0.1065 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874534,"numValue":-0.846486925306047,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874535,"numValue":0.106499876695241,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462671 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,671 | train | mutant | 5,054,421 | 5,060,731 | 5,061,087 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149M | V149M | 1 | 1 | 0 | 0 | 149 | V | M | 9 | CONSERVATION | null | false | false | null | null | 5,440,927 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.836777 | 0.27403 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874536,"numValue":-0.836776537458709,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874537,"numValue":0.274030453482182,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462672 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,672 | train | mutant | 5,054,422 | 5,060,731 | 5,061,088 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149N | V149N | 1 | 1 | 0 | 0 | 149 | V | N | 9 | CONSERVATION | null | false | false | null | null | 5,440,928 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.822754 | 0.456231 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874538,"numValue":-0.822753518974168,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874539,"numValue":0.456230800970157,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462673 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,673 | train | mutant | 5,054,423 | 5,060,731 | 5,061,089 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149P | V149P | 1 | 1 | 0 | 0 | 149 | V | P | 9 | CONSERVATION | null | false | false | null | null | 5,440,929 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.889573 | 0.191897 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874540,"numValue":-0.889573291470902,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874541,"numValue":0.191896682583223,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462675 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,675 | train | mutant | 5,054,425 | 5,060,731 | 5,061,091 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149R | V149R | 1 | 1 | 0 | 0 | 149 | V | R | 9 | CONSERVATION | null | false | false | null | null | 5,440,931 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.83273 | 0.1007 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874544,"numValue":-0.832729638553448,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874545,"numValue":0.100700259299134,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462676 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,676 | train | mutant | 5,054,426 | 5,060,731 | 5,061,092 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149S | V149S | 1 | 1 | 0 | 0 | 149 | V | S | 9 | CONSERVATION | null | false | false | null | null | 5,440,932 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.333777 | 0.063994 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874546,"numValue":-0.333776677124294,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874547,"numValue":0.0639935897487057,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462677 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,677 | train | mutant | 5,054,427 | 5,060,731 | 5,061,093 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149T | V149T | 1 | 1 | 0 | 0 | 149 | V | T | 9 | CONSERVATION | null | false | false | null | null | 5,440,933 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.011159 | 0.237346 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874548,"numValue":-1.0111589769456,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874549,"numValue":0.237345875036812,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462678 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,678 | train | mutant | 5,055,326 | 5,060,731 | 5,061,992 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149W | V149W | 1 | 1 | 0 | 0 | 149 | V | W | 9 | CONSERVATION | null | false | false | null | null | 5,441,834 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.740001 | 0.09456 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876350,"numValue":-0.740001133286459,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876351,"numValue":0.0945603367297343,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462679 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,679 | train | mutant | 5,055,327 | 5,060,731 | 5,061,993 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | V149Y | V149Y | 1 | 1 | 0 | 0 | 149 | V | Y | 9 | CONSERVATION | null | false | false | null | null | 5,441,835 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.97299 | 0.248449 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876352,"numValue":-0.972990208245377,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876353,"numValue":0.248448634589339,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462382,"numValue":9.0,"position":149,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462680 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,680 | train | mutant | 5,054,428 | 5,060,731 | 5,061,094 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delR150 | delR150 | 1 | 0 | 1 | 0 | 150 | R | - | 6 | CONSERVATION | null | false | false | null | null | 5,440,934 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.697366 | 0.274271 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874550,"numValue":-0.697366258231291,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874551,"numValue":0.274271348682714,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462681 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,681 | train | mutant | 5,054,429 | 5,060,731 | 5,061,095 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150A | R150A | 1 | 1 | 0 | 0 | 150 | R | A | 6 | CONSERVATION | null | false | false | null | null | 5,440,935 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.039288 | 0.042566 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874552,"numValue":0.0392876895561268,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874553,"numValue":0.0425664437071875,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462682 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,682 | train | mutant | 5,054,430 | 5,060,731 | 5,061,096 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150C | R150C | 1 | 1 | 0 | 0 | 150 | R | C | 6 | CONSERVATION | null | false | false | null | null | 5,440,936 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.208285 | 0.087682 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874554,"numValue":-0.208285281721446,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874555,"numValue":0.0876815752362543,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462683 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,683 | train | mutant | 5,054,431 | 5,060,731 | 5,061,097 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150D | R150D | 1 | 1 | 0 | 0 | 150 | R | D | 6 | CONSERVATION | null | false | false | null | null | 5,440,937 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.219256 | 0.074204 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874556,"numValue":-0.21925613311487,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874557,"numValue":0.0742036388072399,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462684 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,684 | train | mutant | 5,054,432 | 5,060,731 | 5,061,098 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150E | R150E | 1 | 1 | 0 | 0 | 150 | R | E | 6 | CONSERVATION | null | false | false | null | null | 5,440,938 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.303648 | 0.063439 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874558,"numValue":-0.303647921416959,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874559,"numValue":0.0634388603926758,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462685 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,685 | train | mutant | 5,054,433 | 5,060,731 | 5,061,099 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150F | R150F | 1 | 1 | 0 | 0 | 150 | R | F | 6 | CONSERVATION | null | false | false | null | null | 5,440,939 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.509083 | 0.153352 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874560,"numValue":-0.509082556726175,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874561,"numValue":0.153351918167141,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462686 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,686 | train | mutant | 5,054,434 | 5,060,731 | 5,061,100 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150G | R150G | 1 | 1 | 0 | 0 | 150 | R | G | 6 | CONSERVATION | null | false | false | null | null | 5,440,940 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.478515 | 0.051624 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874562,"numValue":-0.478514596649782,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874563,"numValue":0.0516238478586872,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462687 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,687 | train | mutant | 5,054,435 | 5,060,731 | 5,061,101 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150H | R150H | 1 | 1 | 0 | 0 | 150 | R | H | 6 | CONSERVATION | null | false | false | null | null | 5,440,941 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.251652 | 0.100355 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874564,"numValue":-0.251652164058379,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874565,"numValue":0.10035548482713,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462688 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,688 | train | mutant | 5,054,436 | 5,060,731 | 5,061,102 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150I | R150I | 1 | 1 | 0 | 0 | 150 | R | I | 6 | CONSERVATION | null | false | false | null | null | 5,440,942 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.062971 | 0.108962 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874566,"numValue":0.0629705034265954,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874567,"numValue":0.108962013355222,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462689 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,689 | train | mutant | 5,054,437 | 5,060,731 | 5,061,103 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150K | R150K | 1 | 1 | 0 | 0 | 150 | R | K | 6 | CONSERVATION | null | false | false | null | null | 5,440,943 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.1106 | 0.101692 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874568,"numValue":-0.110600458262736,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874569,"numValue":0.101692443613013,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462690 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,690 | train | mutant | 5,054,438 | 5,060,731 | 5,061,104 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150L | R150L | 1 | 1 | 0 | 0 | 150 | R | L | 6 | CONSERVATION | null | false | false | null | null | 5,440,944 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.067186 | 0.042475 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874570,"numValue":0.0671863290537138,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874571,"numValue":0.0424750018555571,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462691 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,691 | train | mutant | 5,054,439 | 5,060,731 | 5,061,105 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150M | R150M | 1 | 1 | 0 | 0 | 150 | R | M | 6 | CONSERVATION | null | false | false | null | null | 5,440,945 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.136447 | 0.072777 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874572,"numValue":0.136447051180653,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874573,"numValue":0.0727769748115113,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462692 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,692 | train | mutant | 5,054,440 | 5,060,731 | 5,061,106 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150N | R150N | 1 | 1 | 0 | 0 | 150 | R | N | 6 | CONSERVATION | null | false | false | null | null | 5,440,946 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.099556 | 0.205711 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874574,"numValue":-0.0995555442049557,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874575,"numValue":0.205711157205188,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462693 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,693 | train | mutant | 5,054,441 | 5,060,731 | 5,061,107 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150P | R150P | 1 | 1 | 0 | 0 | 150 | R | P | 6 | CONSERVATION | null | false | false | null | null | 5,440,947 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.792405 | 0.131116 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874576,"numValue":-0.792404682228871,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874577,"numValue":0.13111600783085,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462694 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,694 | train | mutant | 5,054,442 | 5,060,731 | 5,061,108 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150Q | R150Q | 1 | 1 | 0 | 0 | 150 | R | Q | 6 | CONSERVATION | null | false | false | null | null | 5,440,948 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.00846 | 0.082846 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874578,"numValue":-0.00846038246023718,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874579,"numValue":0.0828455386422749,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462695 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,695 | train | mutant | 5,055,321 | 5,060,731 | 5,061,987 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150S | R150S | 1 | 1 | 0 | 0 | 150 | R | S | 6 | CONSERVATION | null | false | false | null | null | 5,441,829 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.104289 | 0.059837 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876340,"numValue":-0.10428853154008,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876341,"numValue":0.0598367524798622,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462696 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,696 | train | mutant | 5,055,322 | 5,060,731 | 5,061,988 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150T | R150T | 1 | 1 | 0 | 0 | 150 | R | T | 6 | CONSERVATION | null | false | false | null | null | 5,441,830 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.182145 | 0.074668 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876342,"numValue":-0.182144992031081,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876343,"numValue":0.0746677435548323,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462697 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,697 | train | mutant | 5,055,323 | 5,060,731 | 5,061,989 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150V | R150V | 1 | 1 | 0 | 0 | 150 | R | V | 6 | CONSERVATION | null | false | false | null | null | 5,441,831 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.147992 | 0.042335 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876344,"numValue":-0.147991888222839,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876345,"numValue":0.0423347552620007,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462698 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,698 | train | mutant | 5,055,324 | 5,060,731 | 5,061,990 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150W | R150W | 1 | 1 | 0 | 0 | 150 | R | W | 6 | CONSERVATION | null | false | false | null | null | 5,441,832 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.37309 | 0.059094 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876346,"numValue":-0.373090097071572,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876347,"numValue":0.0590940380353282,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462699 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,699 | train | mutant | 5,055,325 | 5,060,731 | 5,061,991 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | R150Y | R150Y | 1 | 1 | 0 | 0 | 150 | R | Y | 6 | CONSERVATION | null | false | false | null | null | 5,441,833 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.117931 | 0.125453 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876348,"numValue":-0.117930746620292,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876349,"numValue":0.125452640198309,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462383,"numValue":6.0,"position":150,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462700 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,700 | train | mutant | 5,054,443 | 5,060,731 | 5,061,109 | 195 | 194 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | delA151 | delA151 | 1 | 0 | 1 | 0 | 151 | A | - | 7 | CONSERVATION | null | false | false | null | null | 5,440,949 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.599582 | 0.124067 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12874580,"numValue":-0.599581833258446,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12874581,"numValue":0.124066774515101,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462384,"numValue":7.0,"position":151,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462701 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,701 | train | mutant | 5,055,302 | 5,060,731 | 5,061,968 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A151C | A151C | 1 | 1 | 0 | 0 | 151 | A | C | 7 | CONSERVATION | null | false | false | null | null | 5,441,810 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.296903 | 0.087378 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876302,"numValue":-0.296903366579063,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876303,"numValue":0.087378237548015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462384,"numValue":7.0,"position":151,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462702 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,702 | train | mutant | 5,055,303 | 5,060,731 | 5,061,969 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A151D | A151D | 1 | 1 | 0 | 0 | 151 | A | D | 7 | CONSERVATION | null | false | false | null | null | 5,441,811 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.258396 | 0.09444 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876304,"numValue":-0.258395761189408,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876305,"numValue":0.094439537970284,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462384,"numValue":7.0,"position":151,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462703 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,703 | train | mutant | 5,055,304 | 5,060,731 | 5,061,970 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A151E | A151E | 1 | 1 | 0 | 0 | 151 | A | E | 7 | CONSERVATION | null | false | false | null | null | 5,441,812 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.149739 | 0.078335 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876306,"numValue":-0.149738745547661,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876307,"numValue":0.0783351223829662,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462384,"numValue":7.0,"position":151,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462704 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,704 | train | mutant | 5,055,305 | 5,060,731 | 5,061,971 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A151F | A151F | 1 | 1 | 0 | 0 | 151 | A | F | 7 | CONSERVATION | null | false | false | null | null | 5,441,813 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.311929 | 0.105954 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876308,"numValue":-0.311929148846003,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876309,"numValue":0.105953664545612,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462384,"numValue":7.0,"position":151,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462706 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,706 | train | mutant | 5,055,307 | 5,060,731 | 5,061,973 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A151H | A151H | 1 | 1 | 0 | 0 | 151 | A | H | 7 | CONSERVATION | null | false | false | null | null | 5,441,815 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.225638 | 0.136037 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876312,"numValue":-0.225638291674415,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876313,"numValue":0.136037216488839,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462384,"numValue":7.0,"position":151,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462707 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,707 | train | mutant | 5,055,308 | 5,060,731 | 5,061,974 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A151I | A151I | 1 | 1 | 0 | 0 | 151 | A | I | 7 | CONSERVATION | null | false | false | null | null | 5,441,816 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.413199 | 0.10015 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876314,"numValue":-0.413199435272184,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876315,"numValue":0.100149641697919,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462384,"numValue":7.0,"position":151,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||||||||||||||||||
fireprotdb:5462708 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,462,708 | train | mutant | 5,055,309 | 5,060,731 | 5,061,975 | 195 | 195 | 8,258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | 8258 | Apoptosis-associated speck-like protein containing a CARD | Homo sapiens | 1 | Q9ULZ3 | IPR001315|IPR033516|IPR004020|IPR011029|IPR051249 | A151K | A151K | 1 | 1 | 0 | 0 | 151 | A | K | 7 | CONSERVATION | null | false | false | null | null | 5,441,817 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.088194 | 0.074455 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12876316,"numValue":-0.0881939484099273,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12876317,"numValue":0.0744548772419319,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":1462384,"numValue":7.0,"position":151,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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