row_id string | dataset_id string | source_dataset string | source_file string | source_table string | source_sha string | row_index int64 | split string | subject_type string | entry_id int64 | sequence_id int64 | target_sequence_id int64 | source_sequence_length int64 | target_sequence_length int64 | protein_id int64 | protein_name string | organism string | isoform int64 | protein_ids string | protein_names string | organisms string | isoforms string | uniprot_accessions string | interpro_accessions string | ec_numbers string | megascale_ids string | other_references string | mutations string | substitutions string | deletions string | insertions string | mutation_count int64 | substitution_count int64 | deletion_count int64 | insertion_count int64 | first_position int64 | first_source_aa string | first_target_aa string | conservation float64 | feature_types string | pdb_ids string | afdb_ids string | structure_ids string | structure_methods string | structure_resolution_min float64 | residue_positions string | residue_chain_names string | residue_secondary_structures string | residue_in_pocket_any bool | residue_in_tunnel_any bool | residue_asa_mean float64 | residue_bfactor_mean float64 | experiment_id int64 | experiment_dataset string | ph float64 | measure string | method string | buffer string | buffer_conc string | exp_temperature float64 | ion string | ion_conc string | pdb_chain_mutation string | tm float64 | dtm float64 | dg float64 | dg_text string | ddg float64 | dh float64 | dcp float64 | dhvh float64 | cm float64 | m_value float64 | trypsin_ml float64 | chymotrypsin_ml float64 | stabilizing float64 | stabilizing_text string | domainome_fitness float64 | domainome_fitness_std float64 | domainome_ddg float64 | domainome_ddg_std float64 | reversibility string | state string | measurement_types string | measurement_datasets string | annotation_types string | publication_id string | publication_type string | publication_title string | publication_year int64 | publication_doi string | publication_pmid string | publication_journal string | publication_url string | publication_author_count int64 | publication_authors string | annotations_json string | measurements_json string | features_json string |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
fireprotdb:5884 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,884 | train | mutant | 4,889,942 | 69 | 4,896,523 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65H | P65H | 1 | 1 | 0 | 0 | 65 | P | H | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,460 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.174759 | 0.258231 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077602,"numValue":-1.17475871475708,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077603,"numValue":0.258231005449878,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5885 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,885 | train | mutant | 4,889,943 | 69 | 4,896,524 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65I | P65I | 1 | 1 | 0 | 0 | 65 | P | I | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,461 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.003973 | 0.187331 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077604,"numValue":-1.00397340845254,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077605,"numValue":0.187330662875279,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5886 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,886 | train | mutant | 4,889,944 | 69 | 4,896,525 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65K | P65K | 1 | 1 | 0 | 0 | 65 | P | K | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,462 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.852947 | 0.147743 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077606,"numValue":-0.852947142628809,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077607,"numValue":0.147742694967793,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5887 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,887 | train | mutant | 4,889,945 | 69 | 4,896,526 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65L | P65L | 1 | 1 | 0 | 0 | 65 | P | L | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,463 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.687305 | 0.077138 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077608,"numValue":-0.687304914555926,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077609,"numValue":0.0771376535291843,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5888 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,888 | train | mutant | 4,889,946 | 69 | 4,896,527 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65M | P65M | 1 | 1 | 0 | 0 | 65 | P | M | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,464 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.495849 | 0.115208 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077610,"numValue":-0.495849230480534,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077611,"numValue":0.115207838554397,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5889 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,889 | train | mutant | 4,889,947 | 69 | 4,896,528 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65N | P65N | 1 | 1 | 0 | 0 | 65 | P | N | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,465 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.076726 | 0.340701 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077612,"numValue":-1.07672643884763,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077613,"numValue":0.340701290256879,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5890 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,890 | train | mutant | 4,890,007 | 69 | 4,896,588 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65Q | P65Q | 1 | 1 | 0 | 0 | 65 | P | Q | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,525 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.854271 | 0.138344 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077732,"numValue":-0.85427119796146,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077733,"numValue":0.138343584502839,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5891 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,891 | train | mutant | 4,890,008 | 69 | 4,896,589 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65R | P65R | 1 | 1 | 0 | 0 | 65 | P | R | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,526 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.905143 | 0.086891 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077734,"numValue":-0.90514322658847,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077735,"numValue":0.0868914078560515,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5892 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,892 | train | mutant | 4,890,009 | 69 | 4,896,590 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65S | P65S | 1 | 1 | 0 | 0 | 65 | P | S | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,527 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.952149 | 0.101587 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077736,"numValue":-0.952148531417015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077737,"numValue":0.101587261464543,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5893 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,893 | train | mutant | 4,890,010 | 69 | 4,896,591 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65T | P65T | 1 | 1 | 0 | 0 | 65 | P | T | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,528 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.692109 | 0.114628 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077738,"numValue":-0.692109192245915,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077739,"numValue":0.114627906457212,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5894 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,894 | train | mutant | 4,890,011 | 69 | 4,896,592 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65V | P65V | 1 | 1 | 0 | 0 | 65 | P | V | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,529 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.989952 | 0.149349 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077740,"numValue":-0.989951953075587,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077741,"numValue":0.149349428961529,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5895 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,895 | train | mutant | 4,890,012 | 69 | 4,896,593 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65W | P65W | 1 | 1 | 0 | 0 | 65 | P | W | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,530 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.891236 | 0.13124 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077742,"numValue":-0.891236255169579,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077743,"numValue":0.131240450941416,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5896 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,896 | train | mutant | 4,890,013 | 69 | 4,896,594 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | P65Y | P65Y | 1 | 1 | 0 | 0 | 65 | P | Y | 9 | CONSERVATION | 1TIN | 58 | null | 65 | A | S | false | false | 34.17497 | 0.28 | 5,042,531 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -1.13013 | 0.279836 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077744,"numValue":-1.13012985398498,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077745,"numValue":0.279835950183056,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7583,"numValue":9.0,"position":65,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5897 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,897 | train | mutant | 4,889,948 | 69 | 4,896,529 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delR66 | delR66 | 1 | 0 | 1 | 0 | 66 | R | - | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,466 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.696388 | 0.162814 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077614,"numValue":-0.696387698422415,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077615,"numValue":0.162813552139344,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5898 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,898 | train | mutant | 4,889,949 | 69 | 4,896,530 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66A | R66A | 1 | 1 | 0 | 0 | 66 | R | A | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,467 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.068241 | 0.055534 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077616,"numValue":-0.068240626069933,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077617,"numValue":0.0555339863380144,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5899 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,899 | train | mutant | 4,889,950 | 69 | 4,896,531 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66C | R66C | 1 | 1 | 0 | 0 | 66 | R | C | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,468 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.124104 | 0.066619 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077618,"numValue":-0.124104389184589,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077619,"numValue":0.0666193712818304,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5900 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,900 | train | mutant | 4,889,951 | 69 | 4,896,532 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66D | R66D | 1 | 1 | 0 | 0 | 66 | R | D | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,469 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.492985 | 0.117335 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077620,"numValue":-0.492984657415941,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077621,"numValue":0.117335305867789,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5901 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,901 | train | mutant | 4,889,952 | 69 | 4,896,533 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66E | R66E | 1 | 1 | 0 | 0 | 66 | R | E | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,470 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.005494 | 0.07152 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077622,"numValue":0.00549433030950619,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077623,"numValue":0.0715199144611133,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5902 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,902 | train | mutant | 4,889,953 | 69 | 4,896,534 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66F | R66F | 1 | 1 | 0 | 0 | 66 | R | F | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,471 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.279962 | 0.061945 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077624,"numValue":-0.279962084964355,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077625,"numValue":0.0619451599636843,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5903 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,903 | train | mutant | 4,889,954 | 69 | 4,896,535 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66G | R66G | 1 | 1 | 0 | 0 | 66 | R | G | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,472 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.315067 | 0.042752 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077626,"numValue":-0.31506678010316,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077627,"numValue":0.0427518186824862,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5904 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,904 | train | mutant | 4,889,955 | 69 | 4,896,536 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66H | R66H | 1 | 1 | 0 | 0 | 66 | R | H | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,473 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.137661 | 0.144384 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077628,"numValue":0.137660549367588,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077629,"numValue":0.144384019036657,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5905 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,905 | train | mutant | 4,889,956 | 69 | 4,896,537 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66I | R66I | 1 | 1 | 0 | 0 | 66 | R | I | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,474 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.029288 | 0.065954 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077630,"numValue":-0.0292881003595328,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077631,"numValue":0.0659544376572766,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5906 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,906 | train | mutant | 4,889,957 | 69 | 4,896,538 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66K | R66K | 1 | 1 | 0 | 0 | 66 | R | K | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,475 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.065743 | 0.093119 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077632,"numValue":-0.0657430314453677,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077633,"numValue":0.0931185974390992,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5907 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,907 | train | mutant | 4,889,958 | 69 | 4,896,539 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66L | R66L | 1 | 1 | 0 | 0 | 66 | R | L | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,476 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.081764 | 0.042293 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077634,"numValue":-0.0817643978640114,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077635,"numValue":0.042292659288879,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5908 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,908 | train | mutant | 4,889,959 | 69 | 4,896,540 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66M | R66M | 1 | 1 | 0 | 0 | 66 | R | M | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,477 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.091868 | 0.070683 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077636,"numValue":-0.091867595917015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077637,"numValue":0.070683313378502,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5910 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,910 | train | mutant | 4,889,961 | 69 | 4,896,542 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66P | R66P | 1 | 1 | 0 | 0 | 66 | R | P | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,479 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.370828 | 0.079459 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077640,"numValue":-0.370828159921726,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077641,"numValue":0.0794585964825081,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5911 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,911 | train | mutant | 4,889,962 | 69 | 4,896,543 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66Q | R66Q | 1 | 1 | 0 | 0 | 66 | R | Q | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,480 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.078535 | 0.073016 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077642,"numValue":-0.0785345557465843,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077643,"numValue":0.0730158351808653,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5912 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,912 | train | mutant | 4,890,002 | 69 | 4,896,583 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66S | R66S | 1 | 1 | 0 | 0 | 66 | R | S | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,520 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.078587 | 0.041119 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077722,"numValue":-0.0785872768463283,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077723,"numValue":0.0411190210324431,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5913 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,913 | train | mutant | 4,890,003 | 69 | 4,896,584 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66T | R66T | 1 | 1 | 0 | 0 | 66 | R | T | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,521 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.001955 | 0.055794 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077724,"numValue":-0.00195499914238698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077725,"numValue":0.0557940561042775,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5914 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,914 | train | mutant | 4,890,004 | 69 | 4,896,585 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66V | R66V | 1 | 1 | 0 | 0 | 66 | R | V | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,522 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.005596 | 0.051686 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077726,"numValue":-0.00559599386362036,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077727,"numValue":0.0516856519470367,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5915 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,915 | train | mutant | 4,890,005 | 69 | 4,896,586 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66W | R66W | 1 | 1 | 0 | 0 | 66 | R | W | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,523 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.478133 | 0.078915 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077728,"numValue":-0.478132961676091,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077729,"numValue":0.0789147864357452,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5916 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,916 | train | mutant | 4,890,006 | 69 | 4,896,587 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | R66Y | R66Y | 1 | 1 | 0 | 0 | 66 | R | Y | 3 | CONSERVATION | 1TIN | 58 | null | 66 | A | L | true | true | 170.40552 | 0.726667 | 5,042,524 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.08616 | 0.071376 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077730,"numValue":-0.0861604918858453,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077731,"numValue":0.0713760650304293,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7584,"numValue":3.0,"position":66,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5917 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,917 | train | mutant | 4,889,963 | 69 | 4,896,544 | 68 | 67 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | delI67 | delI67 | 1 | 0 | 1 | 0 | 67 | I | - | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,481 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.627046 | 0.123702 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077644,"numValue":-0.627046406935641,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077645,"numValue":0.123701783516748,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5918 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,918 | train | mutant | 4,889,964 | 69 | 4,896,545 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67A | I67A | 1 | 1 | 0 | 0 | 67 | I | A | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,482 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.047223 | 0.048047 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077646,"numValue":-0.0472231707246887,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077647,"numValue":0.0480467534743085,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5919 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,919 | train | mutant | 4,889,965 | 69 | 4,896,546 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67C | I67C | 1 | 1 | 0 | 0 | 67 | I | C | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,483 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | 0.100674 | 0.062185 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077648,"numValue":0.100673908896963,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077649,"numValue":0.0621850859513933,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5921 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,921 | train | mutant | 4,889,967 | 69 | 4,896,548 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67E | I67E | 1 | 1 | 0 | 0 | 67 | I | E | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,485 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.430048 | 0.120337 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077652,"numValue":-0.430047989902855,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077653,"numValue":0.120337349649804,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5922 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,922 | train | mutant | 4,889,968 | 69 | 4,896,549 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67F | I67F | 1 | 1 | 0 | 0 | 67 | I | F | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,486 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.396679 | 0.054034 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077654,"numValue":-0.396679222442483,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077655,"numValue":0.0540343139632123,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5923 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,923 | train | mutant | 4,889,969 | 69 | 4,896,550 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67G | I67G | 1 | 1 | 0 | 0 | 67 | I | G | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,487 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.469388 | 0.064198 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077656,"numValue":-0.46938827660284,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077657,"numValue":0.0641978443873566,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5924 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,924 | train | mutant | 4,889,970 | 69 | 4,896,551 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67H | I67H | 1 | 1 | 0 | 0 | 67 | I | H | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,488 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.69142 | 0.140593 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077658,"numValue":-0.691419949336121,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077659,"numValue":0.140593228016663,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5926 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,926 | train | mutant | 4,889,991 | 69 | 4,896,572 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67L | I67L | 1 | 1 | 0 | 0 | 67 | I | L | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,509 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.037814 | 0.042708 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077700,"numValue":-0.0378143437430584,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077701,"numValue":0.0427076715090316,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5927 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,927 | train | mutant | 4,889,992 | 69 | 4,896,573 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67M | I67M | 1 | 1 | 0 | 0 | 67 | I | M | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,510 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.073416 | 0.075843 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077702,"numValue":-0.0734162006518058,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077703,"numValue":0.0758429456756057,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5928 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,928 | train | mutant | 4,889,993 | 69 | 4,896,574 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67N | I67N | 1 | 1 | 0 | 0 | 67 | I | N | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,511 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.289431 | 0.102539 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077704,"numValue":-0.28943110036873,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077705,"numValue":0.102539480098828,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5929 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,929 | train | mutant | 4,889,994 | 69 | 4,896,575 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67P | I67P | 1 | 1 | 0 | 0 | 67 | I | P | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,512 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.633183 | 0.069555 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077706,"numValue":-0.633183196926499,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077707,"numValue":0.0695549648859077,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5930 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,930 | train | mutant | 4,889,995 | 69 | 4,896,576 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67Q | I67Q | 1 | 1 | 0 | 0 | 67 | I | Q | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,513 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.172317 | 0.077317 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077708,"numValue":-0.172316845255329,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077709,"numValue":0.0773173551070492,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5932 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,932 | train | mutant | 4,889,997 | 69 | 4,896,578 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67S | I67S | 1 | 1 | 0 | 0 | 67 | I | S | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,515 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.23973 | 0.048091 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077712,"numValue":-0.239729768052829,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077713,"numValue":0.0480909816187355,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5933 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,933 | train | mutant | 4,889,998 | 69 | 4,896,579 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67T | I67T | 1 | 1 | 0 | 0 | 67 | I | T | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,516 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.044908 | 0.058591 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077714,"numValue":-0.0449083005942876,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077715,"numValue":0.0585906855263332,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5934 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,934 | train | mutant | 4,889,999 | 69 | 4,896,580 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67V | I67V | 1 | 1 | 0 | 0 | 67 | I | V | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,517 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.063917 | 0.044289 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077716,"numValue":-0.0639168661166898,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077717,"numValue":0.0442885847593778,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5935 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,935 | train | mutant | 4,890,000 | 69 | 4,896,581 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67W | I67W | 1 | 1 | 0 | 0 | 67 | I | W | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,518 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.480694 | 0.120384 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077718,"numValue":-0.480693623691305,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077719,"numValue":0.120383593071763,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5936 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,936 | train | mutant | 4,890,001 | 69 | 4,896,582 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | I67Y | I67Y | 1 | 1 | 0 | 0 | 67 | I | Y | 7 | CONSERVATION | 1TIN | 58 | null | 67 | A | L | true | true | 23.325402 | 0.471579 | 5,042,519 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.322292 | 0.08855 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077720,"numValue":-0.322292089865015,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077721,"numValue":0.0885496933688208,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7585,"numValue":7.0,"position":67,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5937 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,937 | train | mutant | 4,889,971 | 69 | 4,896,552 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68A | G68A | 1 | 1 | 0 | 0 | 68 | G | A | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,489 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.273459 | 0.066189 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077660,"numValue":-0.273458946307698,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077661,"numValue":0.0661891545124341,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5938 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,938 | train | mutant | 4,889,972 | 69 | 4,896,553 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68C | G68C | 1 | 1 | 0 | 0 | 68 | G | C | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,490 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.170729 | 0.066994 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077662,"numValue":-0.170729364359451,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077663,"numValue":0.0669942578868194,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5939 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,939 | train | mutant | 4,889,973 | 69 | 4,896,554 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68D | G68D | 1 | 1 | 0 | 0 | 68 | G | D | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,491 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.061273 | 0.066997 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077664,"numValue":-0.0612734337742318,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077665,"numValue":0.0669968489579331,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5940 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,940 | train | mutant | 4,889,974 | 69 | 4,896,555 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68E | G68E | 1 | 1 | 0 | 0 | 68 | G | E | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,492 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.129738 | 0.157562 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077666,"numValue":-0.129737989566457,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077667,"numValue":0.157562494617736,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5941 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,941 | train | mutant | 4,889,975 | 69 | 4,896,556 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68F | G68F | 1 | 1 | 0 | 0 | 68 | G | F | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,493 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.558828 | 0.126703 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077668,"numValue":-0.558827912931471,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077669,"numValue":0.126702657718051,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5942 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,942 | train | mutant | 4,889,976 | 69 | 4,896,557 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68H | G68H | 1 | 1 | 0 | 0 | 68 | G | H | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,494 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.578698 | 0.184461 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077670,"numValue":-0.578697649728191,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077671,"numValue":0.184461411487843,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5943 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,943 | train | mutant | 4,889,977 | 69 | 4,896,558 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68I | G68I | 1 | 1 | 0 | 0 | 68 | G | I | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,495 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.3792 | 0.10389 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077672,"numValue":-0.379199658780406,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077673,"numValue":0.103889716045857,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5944 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,944 | train | mutant | 4,889,978 | 69 | 4,896,559 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68K | G68K | 1 | 1 | 0 | 0 | 68 | G | K | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,496 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.776855 | 0.216509 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077674,"numValue":-0.776854851342383,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077675,"numValue":0.216509272486709,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5945 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,945 | train | mutant | 4,889,979 | 69 | 4,896,560 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68L | G68L | 1 | 1 | 0 | 0 | 68 | G | L | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,497 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.424814 | 0.074946 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077676,"numValue":-0.424814116220924,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077677,"numValue":0.0749459042605575,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5947 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,947 | train | mutant | 4,889,981 | 69 | 4,896,562 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68N | G68N | 1 | 1 | 0 | 0 | 68 | G | N | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,499 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.220887 | 0.105679 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077680,"numValue":-0.220887103055901,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077681,"numValue":0.105679354469252,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5948 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,948 | train | mutant | 4,889,982 | 69 | 4,896,563 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68P | G68P | 1 | 1 | 0 | 0 | 68 | G | P | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,500 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.301709 | 0.079375 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077682,"numValue":-0.301708908834556,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077683,"numValue":0.0793750434358659,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5949 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,949 | train | mutant | 4,889,983 | 69 | 4,896,564 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68Q | G68Q | 1 | 1 | 0 | 0 | 68 | G | Q | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,501 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.549803 | 0.169914 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077684,"numValue":-0.549803248229546,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077685,"numValue":0.16991362679737,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5950 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,950 | train | mutant | 4,889,984 | 69 | 4,896,565 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68R | G68R | 1 | 1 | 0 | 0 | 68 | G | R | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,502 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.574371 | 0.068379 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077686,"numValue":-0.574371460645779,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077687,"numValue":0.0683789964648244,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5952 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,952 | train | mutant | 4,889,986 | 69 | 4,896,567 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68T | G68T | 1 | 1 | 0 | 0 | 68 | G | T | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,504 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.257673 | 0.064632 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077690,"numValue":-0.257672845547468,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077691,"numValue":0.0646323256279608,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5953 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,953 | train | mutant | 4,889,987 | 69 | 4,896,568 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68V | G68V | 1 | 1 | 0 | 0 | 68 | G | V | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,505 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.179591 | 0.056918 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077692,"numValue":-0.179590827568312,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077693,"numValue":0.0569184010321301,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5954 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,954 | train | mutant | 4,889,988 | 69 | 4,896,569 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68W | G68W | 1 | 1 | 0 | 0 | 68 | G | W | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,506 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.415502 | 0.084056 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077694,"numValue":-0.415502004567322,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077695,"numValue":0.0840564521737723,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5955 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,955 | train | mutant | 4,889,989 | 69 | 4,896,570 | 68 | 68 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | 8 | Inhibitor of trypsin and hageman factor | Cucurbita maxima | 1 | P19873 | IPR000864|IPR036354 | G68Y | G68Y | 1 | 1 | 0 | 0 | 68 | G | Y | 9 | CONSERVATION | 1TIN | 58 | null | 68 | A | L | true | true | 60.902788 | 1.2825 | 5,042,507 | Domainome FITNESS | null | null | null | null | null | null | null | null | null | null | null | null | null | null | -0.382577 | 0.129009 | null | null | DOMAINOME_FITNESS|DOMAINOME_FITNESS_STD | 1910 | ARTICLE | Site-saturation mutagenesis of 500 human protein domains. | 2,025 | 10.1038/s41586-024-08370-4 | 39779847 | Nature;637;885-894 | 1 | Beltran Antoni | [{"datasets":[],"id":12077696,"numValue":-0.382577048002918,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS"},{"datasets":[],"id":12077697,"numValue":0.129009070880234,"references":[],"strValue":null,"type":"DOMAINOME_FITNESS_STD"}] | [{"id":7586,"numValue":9.0,"position":68,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||||||||||
fireprotdb:5956 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,956 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 18,222 | ProTherm | 2 | DSC | Thermal | glycine-HCl | 10 mM | null | NaCl | 0.1 N | 87 | null | null | null | 70 | null | null | null | null | null | null | null | null | null | null | null | Unknown | TM|DH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 166 | ARTICLE | Crevice-forming mutants of bovine pancreatic trypsin inhibitor: stability changes and new hydrophobic surface. | 1,993 | 10.1002/pro.5560020410 | 7686069 | Protein Sci;2;588-96 | 5 | Fuchs J|Kim K S|Tao F|Danishefsky A T|Housset D | [{"numValue":2.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"glycine-HCl","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION"},{... | [{"datasets":[],"id":67234,"numValue":87.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":67235,"numValue":70.0,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":67236,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:5957 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,957 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 18,282 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | null | NaCl | 150 mM | 39.2 | null | null | null | 43 | null | null | null | null | null | null | null | null | null | null | null | Unknown | TM|DH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION"},{"n... | [{"datasets":[],"id":67463,"numValue":39.2,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":67464,"numValue":43.0,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":67465,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:5958 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,958 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 18,283 | ProTherm | 2 | DSC | Thermal | glycine-HCl | 10 mM | null | NaCl | 0.1 N | 87 | null | null | null | 70 | null | null | null | null | null | null | null | null | null | null | null | Unknown | TM|DH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 263 | ARTICLE | Hydrogen exchange identifies native-state motional domains important in protein folding. | 1,993 | 10.1021/bi00088a012 | 7690587 | Biochemistry;32;9600-8 | 3 | Kim K S|Fuchs J A|Woodward C K | [{"numValue":2.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"glycine-HCl","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION"},{... | [{"datasets":[],"id":67466,"numValue":87.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":67467,"numValue":70.0,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":67468,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:5960 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,960 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 18,295 | ProTherm | 2 | DSC | Thermal | glycine-HCl | 10 mM | null | 86 | null | null | null | 67.2 | null | 67.9 | null | null | null | null | null | null | null | null | null | yes | TM|DH|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 1080 | ARTICLE | Thermodynamics of BPTI folding. | 1,993 | 10.1002/pro.5560021204 | 7507751 | Protein Sci;2;2028-36 | 4 | Woodward C|Privalov P L|Kim K S|Makhatadze G I | [{"numValue":2.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"glycine-HCl","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":67505,"numValue":86.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":67506,"numValue":67.2,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":67507,"numValue":67.9,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":67508,"numValue":null,"references":[... | ||||||||||||||||||||||||||
fireprotdb:5963 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,963 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 18,298 | ProTherm | 3.5 | DSC | Thermal | Sodium acetate-Acetic acid | 10 mM | null | 101.5 | null | null | null | 77.3 | null | 75.8 | null | null | null | null | null | null | null | null | null | yes | TM|DH|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 1080 | ARTICLE | Thermodynamics of BPTI folding. | 1,993 | 10.1002/pro.5560021204 | 7507751 | Protein Sci;2;2028-36 | 4 | Woodward C|Privalov P L|Kim K S|Makhatadze G I | [{"numValue":3.5,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium acetate-Acetic acid","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":67517,"numValue":101.5,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":67518,"numValue":77.3,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":67519,"numValue":75.8,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":67520,"numValue":null,"references":... | ||||||||||||||||||||||||||
fireprotdb:5964 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,964 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 18,299 | ProTherm | 4 | DSC | Thermal | Sodium acetate-Acetic acid | 10 mM | null | 104 | null | null | null | 76.8 | null | 77.99 | null | null | null | null | null | null | null | null | null | yes | TM|DH|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 1080 | ARTICLE | Thermodynamics of BPTI folding. | 1,993 | 10.1002/pro.5560021204 | 7507751 | Protein Sci;2;2028-36 | 4 | Woodward C|Privalov P L|Kim K S|Makhatadze G I | [{"numValue":4.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium acetate-Acetic acid","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":67521,"numValue":104.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":67522,"numValue":76.8,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":67523,"numValue":77.99,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":67524,"numValue":null,"references"... | ||||||||||||||||||||||||||
fireprotdb:5965 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,965 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 18,300 | ProTherm | 4.9 | DSC | Thermal | Sodium acetate-Acetic acid | 10 mM | null | 104.5 | null | null | null | 74.6 | null | 77.5 | null | null | null | null | null | null | null | null | null | yes | TM|DH|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 1080 | ARTICLE | Thermodynamics of BPTI folding. | 1,993 | 10.1002/pro.5560021204 | 7507751 | Protein Sci;2;2028-36 | 4 | Woodward C|Privalov P L|Kim K S|Makhatadze G I | [{"numValue":4.9,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Sodium acetate-Acetic acid","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":67525,"numValue":104.5,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":67526,"numValue":74.6,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":67527,"numValue":77.5,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":67528,"numValue":null,"references":... | ||||||||||||||||||||||||||
fireprotdb:5966 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,966 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 18,354 | ProTherm | 4.6 | CD | Thermal | citrate | 5 mM | null | 72.6 | null | null | null | null | null | 51 | null | null | null | null | null | null | null | null | null | yes | TM|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 279 | ARTICLE | Designed replacement of an internal hydration water molecule in BPTI: structural and functional implications of a glycine-to-serine mutation. | 1,993 | 10.1021/bi00068a012 | 7683491 | Biochemistry;32;4564-70 | 4 | Berndt K D|Beunink J|Schr?der W|W?thrich K | [{"numValue":4.6,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"citrate","type":"BUFFER"},{"numValue":null,"strValue":"5 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":67738,"numValue":72.6,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":67739,"numValue":51.0,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":67740,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||||
fireprotdb:5967 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,967 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 19,459 | ProTherm | 5.8 | Absorbance | Thermal | MES-NaOH | 30 mM | null | 65.7 | null | null | null | null | 2.97 | 145.08 | null | null | null | null | null | null | null | null | null | yes | TM|DCP|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 1247 | ARTICLE | Denaturation of free and complexed bovine trypsinogen with the calcium ion, dipeptide Ile-Val and basic pancreatic trypsin inhibitor (Kunitz). | 1,994 | 10.1111/j.1432-1033.1994.tb19071.x | 7519988 | Eur J Biochem;223;939-46 | 2 | Otlewski J|Bulaj G | [{"numValue":5.8,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"Absorbance","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"MES-NaOH","type":"BUFFER"},{"numValue":null,"strValue":"30 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":71638,"numValue":65.7,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":71639,"numValue":2.97,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":71640,"numValue":145.08,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":71641,"numValue":null,"references... | ||||||||||||||||||||||||||
fireprotdb:5968 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,968 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 19,706 | ProTherm | 4.7 | CD | Thermal | acetate | 20 mM | null | 38 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | TM|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 917 | ARTICLE | Folding of bovine pancreatic trypsin inhibitor (BPTI) variants in which almost half the residues are alanine. | 2,000 | 10.1006/jmbi.2000.3622 | 10772865 | J Mol Biol;298;493-501 | 2 | Kuroda Y|Kim P S | [{"numValue":4.7,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"acetate","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":72483,"numValue":38.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":72484,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||||
fireprotdb:5969 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,969 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 19,707 | ProTherm | 4.7 | CD | Thermal | acetate | 20 mM | null | 39 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | TM|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 917 | ARTICLE | Folding of bovine pancreatic trypsin inhibitor (BPTI) variants in which almost half the residues are alanine. | 2,000 | 10.1006/jmbi.2000.3622 | 10772865 | J Mol Biol;298;493-501 | 2 | Kuroda Y|Kim P S | [{"numValue":4.7,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"acetate","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":72485,"numValue":39.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":72486,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||||
fireprotdb:5970 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,970 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 19,708 | ProTherm | 4.7 | CD | Thermal | acetate | 20 mM | null | 20 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | TM|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC | 917 | ARTICLE | Folding of bovine pancreatic trypsin inhibitor (BPTI) variants in which almost half the residues are alanine. | 2,000 | 10.1006/jmbi.2000.3622 | 10772865 | J Mol Biol;298;493-501 | 2 | Kuroda Y|Kim P S | [{"numValue":4.7,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"CD","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"acetate","type":"BUFFER"},{"numValue":null,"strValue":"20 mM","type":"BUFFER_CONC"}] | [{"datasets":[],"id":72487,"numValue":20.0,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":72488,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||||
fireprotdb:5971 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,971 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 20,340 | ProTherm | 3.5 | NMR | Urea | HCl | 30 | null | null | 6.6 | null | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER | 1346 | ARTICLE | Protein internal flexibility and global stability: effect of urea on hydrogen exchange rates of bovine pancreatic trypsin inhibitor. | 1,993 | 10.1021/bi00088a013 | 7690588 | Biochemistry;32;9609-13 | 2 | Woodward C|Kim K S | [{"numValue":3.5,"strValue":null,"type":"PH"},{"numValue":30.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"NMR","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"HCl","type":"BUFFER"}] | [{"datasets":[],"id":74429,"numValue":6.6,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":74430,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | |||||||||||||||||||||||||||
fireprotdb:5972 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,972 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 20,524 | ProTherm | 2 | DSC | Thermal | glycine-HCl | 10 mM | 25 | NaCl | 0.1 M | null | null | 9 | null | null | 0.7 | null | null | null | null | null | null | null | null | null | null | Unknown | DCP|DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 263 | ARTICLE | Hydrogen exchange identifies native-state motional domains important in protein folding. | 1,993 | 10.1021/bi00088a012 | 7690587 | Biochemistry;32;9600-8 | 3 | Kim K S|Fuchs J A|Woodward C K | [{"numValue":2.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"glycine-HCl","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFE... | [{"datasets":[],"id":74992,"numValue":0.7,"references":[],"strValue":null,"type":"DCP"},{"datasets":[],"id":74993,"numValue":9.0,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":74994,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:5973 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,973 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 20,645 | ProTherm | 2 | DSC | Thermal | glycine-HCl | 10 mM | 25 | NaCl | 0.1 N | null | null | 9 | null | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 166 | ARTICLE | Crevice-forming mutants of bovine pancreatic trypsin inhibitor: stability changes and new hydrophobic surface. | 1,993 | 10.1002/pro.5560020410 | 7686069 | Protein Sci;2;588-96 | 5 | Fuchs J|Kim K S|Tao F|Danishefsky A T|Housset D | [{"numValue":2.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"glycine-HCl","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFE... | [{"datasets":[],"id":75399,"numValue":9.0,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":75400,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:5974 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,974 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 20,723 | ProTherm | 8.7 | HPLC | GSSG, GSH | Tris-HCl | 0.1 M | 25 | KCl | 0.2 M | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 693 | ARTICLE | Probing the determinants of disulfide stability in native pancreatic trypsin inhibitor. | 1,993 | 10.1021/bi00062a015 | 7681323 | Biochemistry;32;2835-44 | 4 | Goldenberg D P|Bekeart L S|Laheru D A|Zhou J D | [{"numValue":8.7,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"HPLC","type":"MEASURE"},{"numValue":null,"strValue":"GSSG, GSH","type":"METHOD"},{"numValue":null,"strValue":"Tris-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","type":"BUFFE... | [{"datasets":[],"id":75691,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:5975 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,975 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 20,767 | ProTherm | 2 | DSC | Thermal | Potassium phosphate | 1 mM | 25 | NaCl | 0.1 M | null | null | 11.8 | null | null | null | null | null | null | null | null | null | null | null | null | null | no | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 1386 | ARTICLE | Stability studies on derivatives of the bovine pancreatic trypsin inhibitor. | 1,987 | 10.1021/bi00386a044 | 2443162 | Biochemistry;26;3544-51 | 5 | Schwarz H|Mehlich A|Tschesche H|Hinz H J|Wenzel H R | [{"numValue":2.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"1 mM","type"... | [{"datasets":[],"id":75825,"numValue":11.8,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":75826,"numValue":null,"references":[],"strValue":"no","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:5976 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,976 | train | sequence | 76 | 76 | -1 | 100 | -1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | 0 | 0 | 0 | 0 | -1 | null | null | false | false | null | null | 20,768 | ProTherm | 5 | DSC | Thermal | Potassium phosphate | 1 mM | 25 | NaCl | 0.1 M | null | null | 14.3 | null | null | null | null | null | null | null | null | null | null | null | null | null | no | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC | 1386 | ARTICLE | Stability studies on derivatives of the bovine pancreatic trypsin inhibitor. | 1,987 | 10.1021/bi00386a044 | 2443162 | Biochemistry;26;3544-51 | 5 | Schwarz H|Mehlich A|Tschesche H|Hinz H J|Wenzel H R | [{"numValue":5.0,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"Potassium phosphate","type":"BUFFER"},{"numValue":null,"strValue":"1 mM","type"... | [{"datasets":[],"id":75827,"numValue":14.3,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":75828,"numValue":null,"references":[],"strValue":"no","type":"REVERSIBILITY"}] | ||||||||||||||||||||||||
fireprotdb:5977 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,977 | train | mutant | 1,553 | 76 | 1,752 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | R36A | R36A | 1 | 1 | 0 | 0 | 36 | R | A | 3 | CONSERVATION | 1BPI | 57 | null | 36 | A | L | false | false | 151.693995 | 17.623636 | 2,943 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | null | NaCl | 150 mM | 1BPI_A:R1A | 35.3 | -3.9 | null | null | 41 | null | null | null | null | null | null | null | null | null | null | null | Unknown | TM|DTM|DH|REVERSIBILITY | AUTOMUTE_S1962.csv|EASE-MM_S543.csv|HotMuSiC_S1626.csv|PoPMuSiC-2.0_S2648.csv|STRUM_Q3421.csv|AUTOMUTE_S1749.csv|Saraboji_S1791.csv|Broom_S605.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION"},{"n... | [{"datasets":["AUTOMUTE_S1962.csv","EASE-MM_S543.csv","HotMuSiC_S1626.csv","PoPMuSiC-2.0_S2648.csv","STRUM_Q3421.csv"],"id":10669,"numValue":35.3,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","AUTOMUTE_S1962.csv","EASE-MM_S543.csv","HotMuSiC_S1626.csv","PoPMuSiC-2.0_S2648.csv","Saraboji... | [{"id":7622,"numValue":3.0,"position":36,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5978 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,978 | train | mutant | 1,553 | 76 | 1,752 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | R36A | R36A | 1 | 1 | 0 | 0 | 36 | R | A | 3 | CONSERVATION | 1BPI | 57 | null | 36 | A | L | false | false | 151.693995 | 17.623636 | 8,162 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | 39 | NaCl | 150 mM | 1BPI_A:R1A | null | null | null | 0.5 | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | DDG|REVERSIBILITY | capriotti_S1615_map.csv|guerios_625_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":39.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_... | [{"datasets":["capriotti_S1615_map.csv","guerios_625_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":27714,"numValue":0.5,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":27715,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | [{"id":7622,"numValue":3.0,"position":36,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5979 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,979 | train | mutant | 1,554 | 76 | 1,753 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | P37A | P37A | 1 | 1 | 0 | 0 | 37 | P | A | 5 | CONSERVATION | 1BPI | 57 | null | 37 | A | L | false | false | 62.628925 | 15.695714 | 2,944 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | null | NaCl | 150 mM | 1BPI_A:P2A | 29.4 | -9.8 | null | null | 37 | null | null | null | null | null | null | null | null | null | null | null | Unknown | TM|DTM|DH|REVERSIBILITY | AUTOMUTE_S1962.csv|EASE-MM_S543.csv|HotMuSiC_S1626.csv|PoPMuSiC-2.0_S2648.csv|STRUM_Q3421.csv|AUTOMUTE_S1749.csv|Saraboji_S1791.csv|Broom_S605.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION"},{"n... | [{"datasets":["AUTOMUTE_S1962.csv","EASE-MM_S543.csv","HotMuSiC_S1626.csv","PoPMuSiC-2.0_S2648.csv","STRUM_Q3421.csv"],"id":10673,"numValue":29.4,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","AUTOMUTE_S1962.csv","EASE-MM_S543.csv","HotMuSiC_S1626.csv","PoPMuSiC-2.0_S2648.csv","Saraboji... | [{"id":7623,"numValue":5.0,"position":37,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5980 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,980 | train | mutant | 1,554 | 76 | 1,753 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | P37A | P37A | 1 | 1 | 0 | 0 | 37 | P | A | 5 | CONSERVATION | 1BPI | 57 | null | 37 | A | L | false | false | 62.628925 | 15.695714 | 8,163 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | 39 | NaCl | 150 mM | 1BPI_A:P2A | null | null | null | 1.3 | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | DDG|REVERSIBILITY | capriotti_S1615_map.csv|guerios_625_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":39.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_... | [{"datasets":["capriotti_S1615_map.csv","guerios_625_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":27716,"numValue":1.3,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":27717,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | [{"id":7623,"numValue":5.0,"position":37,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5981 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,981 | train | mutant | 1,555 | 76 | 1,754 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | D38A | D38A | 1 | 1 | 0 | 0 | 38 | D | A | 4 | CONSERVATION | 1BPI | 57 | null | 38 | A | G | false | false | 116.602292 | 19.335 | 2,945 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | null | NaCl | 150 mM | 1BPI_A:D3A | 40.6 | 1.4 | null | null | 44 | null | null | null | null | null | null | null | null | null | null | null | Unknown | TM|DTM|DH|REVERSIBILITY | AUTOMUTE_S1962.csv|Broom_S605.csv|HotMuSiC_S1626.csv|STRUM_Q3421.csv|AUTOMUTE_S1749.csv|EASE-MM_S543.csv|PoPMuSiC-2.0_S2648.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION"},{"n... | [{"datasets":["AUTOMUTE_S1962.csv","Broom_S605.csv","HotMuSiC_S1626.csv","STRUM_Q3421.csv"],"id":10677,"numValue":40.6,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","AUTOMUTE_S1962.csv","Broom_S605.csv","EASE-MM_S543.csv","HotMuSiC_S1626.csv","PoPMuSiC-2.0_S2648.csv","Saraboji_S1791.csv... | [{"id":7624,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5982 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,982 | train | mutant | 1,555 | 76 | 1,754 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | D38A | D38A | 1 | 1 | 0 | 0 | 38 | D | A | 4 | CONSERVATION | 1BPI | 57 | null | 38 | A | G | false | false | 116.602292 | 19.335 | 8,164 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | 39 | NaCl | 150 mM | 1BPI_A:D3A | null | null | null | -0.2 | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | DDG|REVERSIBILITY | capriotti_S1615_map.csv|guerios_625_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":39.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_... | [{"datasets":["capriotti_S1615_map.csv","guerios_625_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":27718,"numValue":-0.2,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":27719,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | [{"id":7624,"numValue":4.0,"position":38,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5983 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,983 | train | mutant | 1,556 | 76 | 1,755 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | F39A | F39A | 1 | 1 | 0 | 0 | 39 | F | A | 4 | CONSERVATION | 1BPI | 57 | null | 39 | A | G | false | false | 21.604457 | 11.619091 | 2,946 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | null | NaCl | 150 mM | 1BPI_A:F4A | 18 | -21 | null | null | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | TM|DTM|REVERSIBILITY | AUTOMUTE_S1962.csv|EASE-MM_S543.csv|PoPMuSiC-2.0_S2648.csv|STRUM_Q3421.csv|AUTOMUTE_S1749.csv|HotMuSiC_S1626.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION"},{"n... | [{"datasets":["AUTOMUTE_S1962.csv","EASE-MM_S543.csv","PoPMuSiC-2.0_S2648.csv","STRUM_Q3421.csv"],"id":10681,"numValue":18.0,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","AUTOMUTE_S1962.csv","EASE-MM_S543.csv","HotMuSiC_S1626.csv","PoPMuSiC-2.0_S2648.csv","Saraboji_S1791.csv","STRUM_Q3... | [{"id":7625,"numValue":4.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5984 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,984 | train | mutant | 1,556 | 76 | 1,755 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | F39A | F39A | 1 | 1 | 0 | 0 | 39 | F | A | 4 | CONSERVATION | 1BPI | 57 | null | 39 | A | G | false | false | 21.604457 | 11.619091 | 8,165 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | 39 | NaCl | 150 mM | 1BPI_A:F4A | null | null | null | 3 | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | DDG|REVERSIBILITY | capriotti_S1615_map.csv|guerios_625_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":39.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_... | [{"datasets":["capriotti_S1615_map.csv","guerios_625_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":27720,"numValue":3.0,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":27721,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | [{"id":7625,"numValue":4.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5985 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,985 | train | mutant | 4,816 | 76 | 5,357 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | F39L | F39L | 1 | 1 | 0 | 0 | 39 | F | L | 4 | CONSERVATION | 1BPI | 57 | null | 39 | A | G | false | false | 21.604457 | 11.619091 | 11,321 | ProTherm | 8.7 | Gel electrophoresis | Urea | Tris-HCl | 0.1 M | 25 | KCl | 0.2 M | 1BPI_A:F4L | null | null | 2.2 | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 755 | ARTICLE | Mutational analysis of the BPTI folding pathway: II. Effects of aromatic-->leucine substitutions on folding kinetics and thermodynamics. | 1,997 | 10.1002/pro.5560060720 | 9232657 | Protein Sci;6;1563-76 | 2 | Goldenberg D P|Zhang J X | [{"numValue":8.7,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"Gel electrophoresis","type":"MEASURE"},{"numValue":null,"strValue":"Urea","type":"METHOD"},{"numValue":null,"strValue":"Tris-HCl","type":"BUFFER"},{"numValue":null,"strValue":"0.1 M","ty... | [{"datasets":[],"id":38982,"numValue":2.2,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":38983,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":7625,"numValue":4.0,"position":39,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||
fireprotdb:5986 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,986 | train | mutant | 456 | 76 | 505 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | L41M | L41M | 1 | 1 | 0 | 0 | 41 | L | M | 3 | CONSERVATION | 1BPI | 57 | null | 41 | A | G | false | false | 110.127181 | 9.81125 | 749 | ProTherm | 4.3 | DSC | Thermal | acetate/Na | 10 mM | null | 1BPI_A:L6M | 99.3 | null | null | null | 77.3 | null | 78.1 | null | null | null | null | null | null | null | null | null | yes | TM|DH|DHVH|REVERSIBILITY | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 84 | ARTICLE | Thermodynamics of single peptide bond cleavage in bovine pancreatic trypsin inhibitor (BPTI). | 2,002 | 10.1110/ps.4460102 | 11910035 | Protein Sci;11;924-32 | 3 | Buczek Olga|Krowarsch Daniel|Otlewski Jacek | [{"numValue":4.3,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"acetate/Na","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"1BPI_A:L6M","type":"_P... | [{"datasets":[],"id":2863,"numValue":99.3,"references":[],"strValue":null,"type":"TM"},{"datasets":[],"id":2864,"numValue":77.3,"references":[],"strValue":null,"type":"DH"},{"datasets":[],"id":2865,"numValue":78.1,"references":[],"strValue":null,"type":"DHVH"},{"datasets":[],"id":2866,"numValue":null,"references":[],"s... | [{"id":7627,"numValue":3.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:5987 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,987 | train | mutant | 456 | 76 | 505 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | L41M | L41M | 1 | 1 | 0 | 0 | 41 | L | M | 3 | CONSERVATION | 1BPI | 57 | null | 41 | A | G | false | false | 110.127181 | 9.81125 | 8,850 | ProTherm | 4.3 | DSC | Thermal | GlyGly/HCl | 10 mM | 25 | 1BPI_A:L6M | null | null | 12.4 | null | null | null | null | null | null | null | null | null | null | null | null | null | yes | DG|REVERSIBILITY | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|_PDB_CHAIN_MUTATION | 84 | ARTICLE | Thermodynamics of single peptide bond cleavage in bovine pancreatic trypsin inhibitor (BPTI). | 2,002 | 10.1110/ps.4460102 | 11910035 | Protein Sci;11;924-32 | 3 | Buczek Olga|Krowarsch Daniel|Otlewski Jacek | [{"numValue":4.3,"strValue":null,"type":"PH"},{"numValue":25.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"GlyGly/HCl","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER... | [{"datasets":[],"id":29987,"numValue":12.4,"references":[],"strValue":null,"type":"DG"},{"datasets":[],"id":29988,"numValue":null,"references":[],"strValue":"yes","type":"REVERSIBILITY"}] | [{"id":7627,"numValue":3.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | ||||||||||||||
fireprotdb:5988 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,988 | train | mutant | 1,557 | 76 | 1,756 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | L41A | L41A | 1 | 1 | 0 | 0 | 41 | L | A | 3 | CONSERVATION | 1BPI | 57 | null | 41 | A | G | false | false | 110.127181 | 9.81125 | 2,947 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | null | NaCl | 150 mM | 1BPI_A:L6A | 34.6 | -4.6 | null | null | 40 | null | null | null | null | null | null | null | null | null | null | null | Unknown | TM|DTM|DH|REVERSIBILITY | AUTOMUTE_S1962.csv|Broom_S605.csv|EASE-MM_S543.csv|HotMuSiC_S1626.csv|PoPMuSiC-2.0_S2648.csv|STRUM_Q3421.csv|AUTOMUTE_S1749.csv|Saraboji_S1791.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION"},{"n... | [{"datasets":["AUTOMUTE_S1962.csv","Broom_S605.csv","EASE-MM_S543.csv","HotMuSiC_S1626.csv","PoPMuSiC-2.0_S2648.csv","STRUM_Q3421.csv"],"id":10684,"numValue":34.6,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","AUTOMUTE_S1962.csv","Broom_S605.csv","EASE-MM_S543.csv","HotMuSiC_S1626.csv",... | [{"id":7627,"numValue":3.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5989 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,989 | train | mutant | 1,557 | 76 | 1,756 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | L41A | L41A | 1 | 1 | 0 | 0 | 41 | L | A | 3 | CONSERVATION | 1BPI | 57 | null | 41 | A | G | false | false | 110.127181 | 9.81125 | 8,166 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | 39 | NaCl | 150 mM | 1BPI_A:L6A | null | null | null | 0.6 | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | DDG|REVERSIBILITY | capriotti_S1615_map.csv|guerios_625_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":39.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_... | [{"datasets":["capriotti_S1615_map.csv","guerios_625_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":27722,"numValue":0.6,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":27723,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | [{"id":7627,"numValue":3.0,"position":41,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5991 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,991 | train | mutant | 1,558 | 76 | 1,757 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | E42A | E42A | 1 | 1 | 0 | 0 | 42 | E | A | 6 | CONSERVATION | 1BPI | 57 | null | 42 | A | S | true | false | 48.33347 | 12.681111 | 8,167 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | 39 | NaCl | 150 mM | 1BPI_A:E7A | null | null | null | 1.5 | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | DDG|REVERSIBILITY | capriotti_S1615_map.csv|guerios_625_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":39.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_... | [{"datasets":["capriotti_S1615_map.csv","guerios_625_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":27724,"numValue":1.5,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":27725,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | [{"id":7628,"numValue":6.0,"position":42,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5992 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,992 | train | mutant | 1,559 | 76 | 1,758 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | P43A | P43A | 1 | 1 | 0 | 0 | 43 | P | A | 6 | CONSERVATION | 1BPI | 57 | null | 43 | A | L | true | false | 103.214713 | 8.315714 | 2,949 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | null | NaCl | 150 mM | 1BPI_A:P8A | 36.7 | -2.5 | null | null | 40 | null | null | null | null | null | null | null | null | null | null | null | Unknown | TM|DTM|DH|REVERSIBILITY | AUTOMUTE_S1962.csv|EASE-MM_S543.csv|HotMuSiC_S1626.csv|PoPMuSiC-2.0_S2648.csv|STRUM_Q3421.csv|AUTOMUTE_S1749.csv|Broom_S605.csv|Saraboji_S1791.csv|Saraboji_S2204.csv | PH|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_CONC"},{"numValue":null,"strValue":"NaCl","type":"ION"},{"n... | [{"datasets":["AUTOMUTE_S1962.csv","EASE-MM_S543.csv","HotMuSiC_S1626.csv","PoPMuSiC-2.0_S2648.csv","STRUM_Q3421.csv"],"id":10692,"numValue":36.7,"references":[],"strValue":null,"type":"TM"},{"datasets":["AUTOMUTE_S1749.csv","AUTOMUTE_S1962.csv","Broom_S605.csv","EASE-MM_S543.csv","PoPMuSiC-2.0_S2648.csv","Saraboji_S17... | [{"id":7629,"numValue":6.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] | |||||||||||
fireprotdb:5993 | fireprotdb | LiteFold/FireProtDB | labeled/fireprotdb/fireprotdb_search_all.jsonl | tables/labeled_fireprotdb_fireprotdb_search_all.jsonl.jsonl | 79354b4f8754e21c3eb41aaf3dd63ba34ae750cd | 5,993 | train | mutant | 1,559 | 76 | 1,758 | 100 | 100 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | 9 | Pancreatic trypsin inhibitor | Bos taurus | 1 | P00974 | IPR002223|IPR036880|IPR020901|IPR050098 | P43A | P43A | 1 | 1 | 0 | 0 | 43 | P | A | 6 | CONSERVATION | 1BPI | 57 | null | 43 | A | L | true | false | 103.214713 | 8.315714 | 8,168 | ProTherm | 7 | DSC | Thermal | phosphate | 10 mM | 39 | NaCl | 150 mM | 1BPI_A:P8A | null | null | null | 0.3 | null | null | null | null | null | null | null | null | null | null | null | null | Unknown | DDG|REVERSIBILITY | capriotti_S1615_map.csv|guerios_625_map.csv|khan_protherm_data_mapped.csv|potapov_with_uniprot_mapping.csv | PH|EXP_TEMPERATURE|MEASURE|METHOD|BUFFER|BUFFER_CONC|ION|ION_CONC|_PDB_CHAIN_MUTATION | 262 | ARTICLE | Contribution of individual side-chains to the stability of BPTI examined by alanine-scanning mutagenesis. | 1,995 | 10.1006/jmbi.1995.0304 | 7540212 | J Mol Biol;249;388-97 | 3 | Yu M H|Weissman J S|Kim P S | [{"numValue":7.0,"strValue":null,"type":"PH"},{"numValue":39.0,"strValue":null,"type":"EXP_TEMPERATURE"},{"numValue":null,"strValue":"DSC","type":"MEASURE"},{"numValue":null,"strValue":"Thermal","type":"METHOD"},{"numValue":null,"strValue":"phosphate","type":"BUFFER"},{"numValue":null,"strValue":"10 mM","type":"BUFFER_... | [{"datasets":["capriotti_S1615_map.csv","guerios_625_map.csv","khan_protherm_data_mapped.csv","potapov_with_uniprot_mapping.csv"],"id":27726,"numValue":0.3,"references":[],"strValue":null,"type":"DDG"},{"datasets":[],"id":27727,"numValue":null,"references":[],"strValue":"Unknown","type":"REVERSIBILITY"}] | [{"id":7629,"numValue":6.0,"position":43,"positionArray":null,"positionRange":null,"strValue":null,"type":"CONSERVATION"}] |
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