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go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0072492
72,492
host cell mitochondrial intermembrane space
cellular_component
The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope.
[ "GOC:ecd" ]
null
[]
[]
[]
[]
[]
[ "GO:0033655" ]
[ "part_of GO:0044190" ]
[ "part_of" ]
[ "GO:0044190" ]
[ "GO:0033655", "GO:0044190" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-15T11:44:02Z
false
true
3
GO:0072493
72,493
host cell endosome lumen
cellular_component
The volume enclosed by the membranes of the host cell endosome.
[ "GOC:ecd" ]
null
[ "host endosome lumen" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0033655" ]
[ "part_of GO:0044174" ]
[ "part_of" ]
[ "GO:0044174" ]
[ "GO:0033655", "GO:0044174" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-15T11:45:53Z
false
true
3
GO:0072494
72,494
host multivesicular body
cellular_component
A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm.
[ "GOC:rph" ]
null
[ "host cell multivesicular body" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0044184" ]
[]
[]
[]
[ "GO:0044184" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-15T11:48:39Z
false
true
7
GO:0072495
72,495
host cell Cajal body
cellular_component
A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers ...
[ "GOC:rph" ]
null
[ "coiled body of host", "host cell coiled body" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0044094" ]
[ "part_of GO:0044095" ]
[ "part_of" ]
[ "GO:0044095" ]
[ "GO:0044094", "GO:0044095" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-15T11:51:12Z
false
true
8
GO:0072496
72,496
Pup transferase activity
molecular_function
Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y = Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages.
[ "GOC:sp" ]
null
[ "Pup conjugating enzyme activity" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0019787" ]
[]
[]
[]
[ "GO:0019787" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-15T11:58:13Z
false
true
4
GO:0072497
72,497
mesenchymal stem cell differentiation
biological_process
The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
[ "CL:0002452", "GOC:BHF" ]
null
[]
[]
[]
[]
[]
[ "GO:0048863" ]
[]
[]
[]
[ "GO:0048863" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-15T12:59:30Z
false
true
9
GO:0072498
72,498
embryonic skeletal joint development
biological_process
The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure.
[ "GOC:BHF", "GOC:vk" ]
null
[]
[]
[]
[]
[]
[ "GO:0048706" ]
[]
[]
[]
[ "GO:0048706" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-15T04:14:42Z
false
true
2
GO:0072499
72,499
photoreceptor cell axon guidance
biological_process
The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.
[ "GOC:sart", "PMID:20826677" ]
null
[ "photoreceptor cell axon pathfinding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007411" ]
[]
[]
[]
[ "GO:0007411" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-15T05:34:10Z
false
true
4
GO:0072500
72,500
obsolete negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor
biological_process
OBSOLETE. Any process in which a ligand-bound hormone receptor acts in the nucleus to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
[ "GOC:mah" ]
This term was made obsolete because it is unclear whether the term represents the action of the receptor or the entire process of transcription regulation. The term 'nuclear hormone receptor' is also misleading since many of these receptors reside in the cytoplasm until they are bound by a ligand.
[ "negative regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0000122", "GO:0003713", "GO:0004879", "GO:0030522" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/12739\" xsd:anyURI" ]
mah
2010-12-16T11:47:39Z
true
true
3
GO:0072502
72,502
obsolete cellular trivalent inorganic anion homeostasis
biological_process
OBSOLETE. Any process involved in the maintenance of an internal steady state of trivalent inorganic anions at the level of a cell.
[ "GOC:mah" ]
This term was obsoleted because it is an unnecessary grouping class.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0030002" ]
[]
[]
mah
2010-12-16T12:53:42Z
true
true
1
GO:0072505
72,505
obsolete divalent inorganic anion homeostasis
biological_process
OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell.
[ "GOC:mah" ]
This term was obsoleted because it represents an unnecessary grouping class.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0055081" ]
[]
[]
mah
2010-12-16T01:39:00Z
true
true
3
GO:0072506
72,506
obsolete trivalent inorganic anion homeostasis
biological_process
OBSOLETE. Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell.
[ "GOC:mah" ]
This term was obsoleted because it is an unnecessary grouping class.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0055081" ]
[]
[]
mah
2010-12-16T01:39:39Z
true
true
2
GO:0072507
72,507
obsolete divalent inorganic cation homeostasis
biological_process
OBSOLETE. Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell.
[ "GOC:mah" ]
This term was obsoleted because it is an unnecessary grouping class.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0055080" ]
[]
[]
mah
2010-12-16T03:22:48Z
true
true
5
GO:0072508
72,508
obsolete trivalent inorganic cation homeostasis
biological_process
OBSOLETE. Any process involved in the maintenance of an internal steady state of trivalent cations within an organism or cell.
[ "GOC:mah" ]
This term was obsoleted because it is an unnecessary grouping class.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0055080" ]
[]
[]
mah
2010-12-16T03:26:40Z
true
true
3
GO:0072513
72,513
positive regulation of secondary heart field cardioblast proliferation
biological_process
Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart...
[ "GOC:BHF", "GOC:mah", "GOC:rl" ]
null
[ "negative regulation of second heart field cardioblast proliferation" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0003266", "GO:0008284" ]
[]
[]
[]
[ "GO:0003266", "GO:0008284" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-17T10:16:43Z
false
true
3
GO:0072514
72,514
trehalose transport in response to water deprivation
biological_process
The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0015771" ]
[ "part_of GO:0042631" ]
[ "part_of" ]
[ "GO:0042631" ]
[ "GO:0015771", "GO:0042631" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-21T11:26:14Z
false
true
8
GO:0072515
72,515
trehalose transport in response to desiccation
biological_process
The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0072514" ]
[ "part_of GO:0071465" ]
[ "part_of" ]
[ "GO:0071465" ]
[ "GO:0071465", "GO:0072514" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-21T11:30:31Z
false
true
5
GO:0072517
72,517
host cell viral assembly compartment
cellular_component
A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place.
[ "GOC:BHF", "PMID:20374631" ]
null
[ "host cell viral assembly site", "host cell virion assembly compartment", "viral assembly compartment", "viral assembly site", "virion assembly compartment" ]
[ "RELATED", "EXACT", "EXACT", "RELATED", "EXACT" ]
[ "GO:0072516" ]
[]
[]
[ "GO:0033648", "GO:0039714" ]
[]
[]
[]
[ "GO:0033648", "GO:0039714" ]
[]
[]
[]
[]
[]
[]
mah
2010-12-21T03:08:42Z
false
true
5
GO:0072520
72,520
seminiferous tubule development
biological_process
The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa...
[ "GOC:BHF", "GOC:mah", "UBERON:0001343" ]
null
[]
[]
[]
[]
[]
[ "GO:0035295", "GO:0048608" ]
[ "part_of GO:0008584" ]
[ "part_of" ]
[ "GO:0008584" ]
[ "GO:0008584", "GO:0035295", "GO:0048608" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-04T12:50:36Z
false
true
2
GO:0072521
72,521
purine-containing compound metabolic process
biological_process
The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
[ "GOC:mah" ]
null
[ "purine and derivative metabolic process", "purine-containing compound metabolism" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-04T03:03:59Z
false
true
8
GO:0072522
72,522
purine-containing compound biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
[ "GOC:mah" ]
null
[ "purine and derivative biosynthetic process", "purine-containing compound anabolism", "purine-containing compound biosynthesis", "purine-containing compound formation", "purine-containing compound synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009058", "GO:0072521" ]
[]
[]
[]
[ "GO:0009058", "GO:0072521" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-04T03:15:29Z
false
true
6
GO:0072524
72,524
pyridine-containing compound metabolic process
biological_process
The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
[ "GOC:mah" ]
null
[ "pyridine and derivative metabolic process", "pyridine-containing compound metabolism" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-04T03:21:47Z
false
true
9
GO:0072525
72,525
pyridine-containing compound biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
[ "GOC:mah" ]
null
[ "pyridine and derivative biosynthetic process", "pyridine-containing compound anabolism", "pyridine-containing compound biosynthesis", "pyridine-containing compound formation", "pyridine-containing compound synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009058", "GO:0072524" ]
[]
[]
[]
[ "GO:0009058", "GO:0072524" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-04T03:23:01Z
false
true
5
GO:0072526
72,526
pyridine-containing compound catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
[ "GOC:mah" ]
null
[ "pyridine and derivative catabolic process", "pyridine-containing compound breakdown", "pyridine-containing compound catabolism", "pyridine-containing compound degradation" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009056", "GO:0072524" ]
[]
[]
[]
[ "GO:0009056", "GO:0072524" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-04T03:23:14Z
false
true
1
GO:0072528
72,528
pyrimidine-containing compound biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
[ "GOC:mah" ]
null
[ "pyrimidine and derivative biosynthetic process", "pyrimidine-containing compound anabolism", "pyrimidine-containing compound biosynthesis", "pyrimidine-containing compound formation", "pyrimidine-containing compound synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009058", "GO:0072527" ]
[]
[]
[]
[ "GO:0009058", "GO:0072527" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-04T03:27:36Z
false
true
7
GO:0072529
72,529
pyrimidine-containing compound catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
[ "GOC:mah" ]
null
[ "pyrimidine and derivative catabolic process", "pyrimidine-containing compound breakdown", "pyrimidine-containing compound catabolism", "pyrimidine-containing compound degradation" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009056", "GO:0072527" ]
[]
[]
[]
[ "GO:0009056", "GO:0072527" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-04T03:27:51Z
false
true
1
GO:0072530
72,530
purine-containing compound transmembrane transport
biological_process
The process in which a purine-containing compound is transported across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.
[ "GOC:mah" ]
Note that this term is not intended for use in annotating lateral movement within membranes.
[ "purine-containing compound membrane transport" ]
[ "EXACT" ]
[]
[]
[ "Reactome:R-HSA-2161517 \"Abacavir transmembrane transport\"" ]
[ "GO:0055085", "GO:0071705" ]
[]
[]
[]
[ "GO:0055085", "GO:0071705" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-05T01:45:14Z
false
true
3
GO:0072531
72,531
pyrimidine-containing compound transmembrane transport
biological_process
The process in which a pyrimidine-containing compound is transported across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof.
[ "GOC:mah" ]
Note that this term is not intended for use in annotating lateral movement within membranes.
[ "pyrimidine-containing compound membrane transport" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0055085", "GO:0071705" ]
[]
[]
[]
[ "GO:0055085", "GO:0071705" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-05T01:47:22Z
false
true
6
GO:0072532
72,532
tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity
molecular_function
Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives.
[ "GOC:kad", "PMID:19779199" ]
Note that the overall reaction representing three successive executions of this activity is N1,N5,N10-triferuloyl spermidine + 3 NADPH + 3 O2 = N1,N5,N10-tri-(hydroxyferuloyl)-spermidine + 3 NADP+ + 3 H2O; this corresponds to the MetaCyc reaction RXN-11262 (http://biocyc.org/META/NEW-IMAGE?type=REACTION&object=RXN-1126...
[]
[]
[]
[]
[]
[ "GO:0016709" ]
[]
[]
[]
[ "GO:0016709" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-12T01:54:31Z
false
true
3
GO:0072533
72,533
tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity
molecular_function
Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives.
[ "GOC:kad", "PMID:19779199" ]
Note that the overall reaction representing three successive executions of this activity is N1,N5,N10-tricoumaroyl spermidine + 3 NADPH + 3 O2 = N1,N5,N10-tricaffeoyl spermidine + 3 NADP+ + 3 H2O; this corresponds to the MetaCyc reaction RXN-11260 (http://biocyc.org/META/NEW-IMAGE?type=REACTION&object=RXN-11260).
[]
[]
[]
[]
[]
[ "GO:0016709" ]
[]
[]
[]
[ "GO:0016709" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-12T02:03:07Z
false
true
7
GO:0072534
72,534
perineuronal net
cellular_component
A dense extracellular matrix (ECM) that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain.
[ "GOC:sl", "PMID:18364019" ]
null
[ "PNN" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0098966" ]
[]
[]
[]
[ "GO:0098966" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-14T01:37:40Z
false
true
8
GO:0072535
72,535
tumor necrosis factor (ligand) superfamily member 11 production
biological_process
The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "RANKL production", "TNFSF11 production", "tumor necrosis factor ligand superfamily member 11 production" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0071706" ]
[]
[]
[]
[ "GO:0071706" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-14T01:42:23Z
false
true
6
GO:0072536
72,536
interleukin-23 receptor complex
cellular_component
A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.
[ "GOC:BHF", "GOC:mah", "PMID:12023369" ]
null
[ "IL-23 receptor complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0098802" ]
[]
[]
[]
[ "GO:0098802" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-14T02:51:14Z
false
true
6
GO:0072537
72,537
fibroblast activation
biological_process
A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.
[ "CL:0000057", "GOC:BHF", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0001775" ]
[]
[]
[]
[ "GO:0001775" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-14T04:35:08Z
false
true
2
GO:0072539
72,539
T-helper 17 cell differentiation
biological_process
The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
[ "CL:0000899", "GOC:BHF", "GOC:ebc" ]
Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
[ "T-helper 17 cell development" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0002287", "GO:0002292", "GO:0042093" ]
[ "part_of GO:0072538" ]
[ "part_of" ]
[ "GO:0072538" ]
[ "GO:0002287", "GO:0002292", "GO:0042093", "GO:0072538" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-17T11:18:47Z
false
true
1
GO:0072540
72,540
T-helper 17 cell lineage commitment
biological_process
The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
[ "CL:0000899", "GOC:BHF", "GOC:ebc" ]
null
[ "T-helper 17 cell fate commitment", "Th17 cell lineage commitment", "Th17 fate commitment" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002295" ]
[ "part_of GO:0072539" ]
[ "part_of" ]
[ "GO:0072539" ]
[ "GO:0002295", "GO:0072539" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-17T11:19:48Z
false
true
8
GO:0072541
72,541
peroxynitrite reductase activity
molecular_function
Catalysis of the reaction: [protein]-dithiol + ONOO- = [protein]-disulfide + NO2- + H2O.
[ "GOC:rs", "PMID:11001062" ]
Note that this activity is usually associated in vivo with an NADPH-dependent disulfide reductase activity, so that catalysis of the reduction of peroxynitrite to nitrite involves the possible creation of oxygen or water, using NADPH as reduction equivalent.
[ "peroxynitritase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0004601" ]
[]
[]
[]
[ "GO:0004601" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-17T11:43:37Z
false
true
6
GO:0072544
72,544
L-DOPA binding
molecular_function
Binding to L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid.
[ "GOC:mah", "GOC:vw" ]
null
[]
[]
[]
[]
[]
[ "GO:0016597", "GO:0031406", "GO:0072341" ]
[]
[]
[]
[ "GO:0016597", "GO:0031406", "GO:0072341" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-19T05:40:04Z
false
true
2
GO:0072545
72,545
L-tyrosine binding
molecular_function
Binding to L-tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
[ "GOC:mah" ]
null
[ "L-Tyr binding", "tyrosine binding" ]
[ "EXACT", "BROAD" ]
[]
[]
[]
[ "GO:0016597", "GO:0031406", "GO:0043169" ]
[]
[]
[]
[ "GO:0016597", "GO:0031406", "GO:0043169" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-19T05:43:55Z
false
true
2
GO:0072546
72,546
EMC complex
cellular_component
A transmembrane protein complex located in the endoplasmic reticulum (ER) involved in the insertion of newly synthesized proteins in the membrane of the ER. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6.
[ "PMID:29242231", "PMID:30415835", "PMID:32459176" ]
Note that this complex used to be thought to be involved in ER-mitochondrial membrane tethering, which is required to facilitate lipid transfer from the ER to the mitochondrial membrane, but newer findings show that this was incorrect.
[ "endoplasmic reticulum membrane protein complex", "ER membrane protein complex" ]
[ "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0098796", "GO:0140534" ]
[ "part_of GO:0005789" ]
[ "part_of" ]
[ "GO:0005789" ]
[ "GO:0005789", "GO:0098796", "GO:0140534" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/13657\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20234\" xsd:anyURI" ]
mah
2011-01-19T06:16:53Z
false
true
3
GO:0072547
72,547
tricoumaroylspermidine meta-hydroxylase activity
molecular_function
Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O.
[ "GOC:kad", "PMID:19779199" ]
null
[ "tricoumaroyl spermidine meta-hydroxylase activity" ]
[ "EXACT" ]
[]
[]
[ "MetaCyc:RXN-11260" ]
[ "GO:0072533" ]
[]
[]
[]
[ "GO:0072533" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-25T02:49:37Z
false
true
3
GO:0072548
72,548
dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity
molecular_function
Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O.
[ "GOC:kad", "PMID:19779199" ]
null
[]
[]
[]
[]
[]
[ "GO:0072533" ]
[]
[]
[]
[ "GO:0072533" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-25T02:57:22Z
false
true
7
GO:0072549
72,549
monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity
molecular_function
Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O.
[ "GOC:kad", "PMID:19779199" ]
null
[]
[]
[]
[]
[]
[ "GO:0072533" ]
[]
[]
[]
[ "GO:0072533" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-25T02:58:04Z
false
true
6
GO:0072551
72,551
diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity
molecular_function
Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O.
[ "GOC:kad", "PMID:19779199" ]
null
[]
[]
[]
[]
[]
[ "GO:0072532" ]
[]
[]
[]
[ "GO:0072532" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-25T03:04:16Z
false
true
1
GO:0072552
72,552
monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity
molecular_function
Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O.
[ "GOC:kad", "PMID:19779199" ]
null
[]
[]
[]
[]
[]
[ "GO:0072532" ]
[]
[]
[]
[ "GO:0072532" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-25T03:15:31Z
false
true
7
GO:0072553
72,553
terminal button organization
biological_process
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
[ "GOC:BHF", "GOC:mah" ]
null
[ "bouton organization", "presynaptic bouton organization", "synaptic bouton organization", "terminal bouton organization", "terminal button organisation" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0099172" ]
[]
[]
[]
[ "GO:0099172" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-25T04:09:35Z
false
true
5
GO:0072555
72,555
obsolete 17-beta-ketosteroid reductase (NADPH) activity
molecular_function
OBSOLETE. Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+.
[ "GOC:kad", "PMID:17074428" ]
This term was obsoleted because it was an unnecessary grouping term.
[ "7beta-ketosteroid reductase activity" ]
[ "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0072582" ]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29329\" xsd:anyURI" ]
mah
2011-01-27T11:36:14Z
true
true
4
GO:0072557
72,557
IPAF inflammasome complex
cellular_component
An inflammasome complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.
[ "GOC:add", "GOC:BHF", "GOC:vp", "PMID:20303873" ]
null
[]
[]
[]
[]
[]
[ "GO:0061702" ]
[]
[]
[]
[ "GO:0061702" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-27T12:01:44Z
false
true
1
GO:0072558
72,558
NLRP1 inflammasome complex
cellular_component
An inflammasome complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential.
[ "GOC:add", "GOC:BHF", "GOC:vp", "PMID:20303873" ]
null
[ "NALP1 inflammasome complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0061702" ]
[]
[]
[]
[ "GO:0061702" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-27T12:03:50Z
false
true
1
GO:0072559
72,559
NLRP3 inflammasome complex
cellular_component
An inflammasome complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to ...
[ "GOC:add", "GOC:BHF", "GOC:vp", "PMID:20303873" ]
null
[ "NALP3 inflammasome complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0061702" ]
[]
[]
[]
[ "GO:0061702" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-27T12:04:30Z
false
true
3
GO:0072560
72,560
type B pancreatic cell maturation
biological_process
A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
[ "CL:0000169", "GOC:BHF" ]
These processes continue to 60 DPA in Gossypium spp.
[ "pancreatic B cell maturation", "pancreatic beta cell maturation" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0002070" ]
[ "part_of GO:0003323" ]
[ "part_of" ]
[ "GO:0003323" ]
[ "GO:0002070", "GO:0003323" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-27T01:57:14Z
false
true
3
GO:0072562
72,562
blood microparticle
cellular_component
A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free o...
[ "GOC:BHF", "GOC:mah", "PMID:16373184" ]
null
[ "cell membrane microparticle" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0110165" ]
[ "part_of GO:0005576" ]
[ "part_of" ]
[ "GO:0005576" ]
[ "GO:0005576", "GO:0110165" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-28T11:50:56Z
false
true
2
GO:0072563
72,563
endothelial microparticle
cellular_component
A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell.
[ "GOC:BHF", "GOC:mah", "PMID:16373184" ]
null
[]
[]
[]
[]
[]
[ "GO:0072562" ]
[]
[]
[]
[ "GO:0072562" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-28T01:53:25Z
false
true
1
GO:0072564
72,564
blood microparticle formation
biological_process
The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins character...
[ "GOC:BHF", "GOC:mah", "PMID:16373184" ]
null
[ "microparticle generation", "microparticle release" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0016043", "GO:0048646" ]
[]
[]
[]
[ "GO:0016043", "GO:0048646" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-28T02:15:50Z
false
true
8
GO:0072565
72,565
endothelial microparticle formation
biological_process
The cellular component organization process in which microparticles bud off from an endothelial cell.
[ "GOC:BHF", "GOC:mah", "PMID:16373184" ]
null
[ "endothelial microparticle generation", "endothelial microparticle release" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0072564" ]
[]
[]
[]
[ "GO:0072564" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-28T02:21:58Z
false
true
1
GO:0072566
72,566
chemokine (C-X-C motif) ligand 1 production
biological_process
The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah" ]
null
[ "CXCL1 production", "KC production", "keratinocyte derived chemokine production", "SCYB1 production" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0032602" ]
[]
[]
[]
[ "GO:0032602" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-31T11:31:58Z
false
true
4
GO:0072567
72,567
chemokine (C-X-C motif) ligand 2 production
biological_process
The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah" ]
null
[ "CXCL2 production", "MIP-2 production", "MIP2 production", "SCYB2 production" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0032602" ]
[]
[]
[]
[ "GO:0032602" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-31T11:33:40Z
false
true
6
GO:0072570
72,570
ADP-D-ribose binding
molecular_function
Binding to ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
[ "GOC:mah", "GOC:sart", "PMID:20088964" ]
null
[ "ADP-ribose binding" ]
[ "BROAD" ]
[]
[]
[]
[ "GO:0043168", "GO:0097367", "GO:1901265", "GO:1901363" ]
[]
[]
[]
[ "GO:0043168", "GO:0097367", "GO:1901265", "GO:1901363" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-31T02:37:30Z
false
true
6
GO:0072571
72,571
mono-ADP-D-ribose binding
molecular_function
Binding to monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
[ "GOC:mah", "GOC:sart", "PMID:20088964" ]
null
[ "mADPr binding", "mono-ADP-ribose binding" ]
[ "EXACT", "BROAD" ]
[]
[]
[]
[ "GO:0072570" ]
[]
[]
[]
[ "GO:0072570" ]
[]
[]
[]
[]
[]
[]
mah
2011-01-31T02:39:12Z
false
true
1
GO:0072573
72,573
tolerance induction to lipopolysaccharide
biological_process
Tolerance induction directed at lipopolysaccharide antigens.
[ "GOC:BHF", "GOC:mah" ]
null
[ "tolerance induction to endotoxin", "tolerance induction to LPS" ]
[ "BROAD", "EXACT" ]
[]
[]
[]
[ "GO:0002507", "GO:0031665" ]
[ "part_of GO:0071222" ]
[ "part_of" ]
[ "GO:0071222" ]
[ "GO:0002507", "GO:0031665", "GO:0071222" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-02T03:05:19Z
false
true
2
GO:0072574
72,574
hepatocyte proliferation
biological_process
The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules.
[ "CL:0000182", "GOC:BHF", "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0050673" ]
[]
[]
[]
[ "GO:0050673" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-02T03:34:49Z
false
true
6
GO:0072575
72,575
obsolete epithelial cell proliferation involved in liver morphogenesis
biological_process
OBSOLETE. The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.
[ "GOC:BHF", "GOC:mah" ]
This term was obsoleted because it is a pre-composed term that should be captured as a GO-CAM model.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31330\" xsd:anyURI" ]
mah
2011-02-02T03:37:50Z
true
true
7
GO:0072576
72,576
liver morphogenesis
biological_process
The process in which the anatomical structures of the liver are generated and organized.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0022612" ]
[ "part_of GO:0001889" ]
[ "part_of" ]
[ "GO:0001889" ]
[ "GO:0001889", "GO:0022612" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-02T03:41:30Z
false
true
2
GO:0072577
72,577
endothelial cell apoptotic process
biological_process
Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.
[ "CL:0000115", "GOC:BHF", "GOC:mah", "GOC:mtg_apoptosis" ]
null
[ "apoptosis of endothelial cells", "endothelial cell apoptosis", "endothelial cell programmed cell death by apoptosis", "killing of endothelial cells", "programmed cell death of endothelial cells by apoptosis", "programmed cell death, endothelial cells" ]
[ "EXACT", "NARROW", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006915" ]
[]
[]
[]
[ "GO:0006915" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-02T03:56:24Z
false
true
5
GO:0072578
72,578
neurotransmitter-gated ion channel clustering
biological_process
The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.
[ "GOC:dsf", "PMID:20843816" ]
null
[]
[]
[]
[]
[]
[ "GO:0043113" ]
[ "part_of GO:0050808" ]
[ "part_of" ]
[ "GO:0050808" ]
[ "GO:0043113", "GO:0050808" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-03T01:45:48Z
false
true
4
GO:0072580
72,580
bacterial-type EF-P lysine modification
biological_process
The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P).
[ "GOC:curators", "GOC:imk", "GOC:mah", "PMID:20729861", "PMID:22706199", "RESID:AA0530", "RESID:AA0531" ]
The EF-P modification pathway is now thought to be composed of three steps: conversion of alpha-lysyl-EF-P to beta-lysyl-EF-P, lysylation of Lys34, and hydroxylation of Lys34.
[ "EF-P modification pathway" ]
[ "EXACT" ]
[]
[ "gocheck_obsoletion_candidate" ]
[]
[ "GO:0018205" ]
[]
[]
[]
[ "GO:0018205" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-07T11:47:33Z
false
true
1
GO:0072581
72,581
obsolete protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine
biological_process
OBSOLETE. The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
[ "GOC:jsg", "GOC:mah", "PMID:20729861", "RESID:AA0531" ]
This term was obsoleted because it represents a molecular function.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28482\" xsd:anyURI" ]
mah
2011-02-07T11:51:02Z
true
true
2
GO:0072582
72,582
17-beta-hydroxysteroid dehydrogenase (NADP+) activity
molecular_function
Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.
[ "GOC:kad", "PMID:17074428" ]
null
[]
[]
[]
[]
[ "RHEA:42120", "RHEA:42156", "RHEA:46628", "RHEA:53480", "RHEA:53484", "RHEA:53488", "RHEA:69284", "RHEA:85531", "RHEA:85543" ]
[ "GO:0033764" ]
[]
[]
[]
[ "GO:0033764" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:69284", "skos:narrowMatch RHEA:42120", "skos:narrowMatch RHEA:42156", "skos:narrowMatch RHEA:46628", "skos:narrowMatch RHEA:53480", "skos:narrowMatch RHEA:53484", "skos:narrowMatch RHEA:53488", "skos:narrowMatch RHEA:85531", "skos:narrowMatch RHEA:85543", "term_tracker_item \...
mah
2011-02-07T01:54:21Z
false
true
9
GO:0072583
72,583
clathrin-dependent endocytosis
biological_process
An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
[ "GOC:BHF", "GOC:mah", "PMID:18498251", "PMID:8970738", "PMID:9234965" ]
null
[ "clathrin coated pit-dependent endocytosis", "clathrin-mediated endocytosis", "CME" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0006898" ]
[]
[]
[]
[ "GO:0006898" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-08T03:59:18Z
false
true
3
GO:0072585
72,585
xanthosine nucleotidase activity
molecular_function
Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.
[ "GOC:kad", "MetaCyc:RXN0-363", "PMID:21235647" ]
null
[ "xanthosine ribohydrolase activity" ]
[ "EXACT" ]
[]
[]
[ "MetaCyc:RXN0-363", "RHEA:27994" ]
[ "GO:0008477" ]
[]
[]
[]
[ "GO:0008477" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:27994", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
mah
2011-02-08T04:38:31Z
false
true
6
GO:0072586
72,586
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity
molecular_function
Binds to and modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which...
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0030234" ]
[ "regulates GO:0003918" ]
[ "regulates" ]
[ "GO:0003918" ]
[ "GO:0003918", "GO:0030234" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-09T05:31:50Z
false
true
5
GO:0072587
72,587
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activator activity
molecular_function
Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which...
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0001671", "GO:0008047", "GO:0072586" ]
[ "positively_regulates GO:0003918" ]
[ "positively_regulates" ]
[ "GO:0003918" ]
[ "GO:0001671", "GO:0003918", "GO:0008047", "GO:0072586" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-09T05:34:47Z
false
true
2
GO:0072588
72,588
box H/ACA RNP complex
cellular_component
A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets...
[ "GOC:BHF", "GOC:BHF_telomerase", "GOC:jbu", "GOC:krc", "GOC:mah", "GOC:vw", "PMID:17284456", "PMID:20227365", "PMID:25590339" ]
null
[ "box H/ACA snoRNP pseudouridylase complex", "sRNP complex" ]
[ "RELATED", "NARROW" ]
[]
[]
[]
[ "GO:0005732" ]
[]
[]
[]
[ "GO:0005732" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20416\" xsd:anyURI" ]
mah
2011-02-10T01:43:37Z
false
true
2
GO:0072590
72,590
N-acetyl-L-aspartate-L-glutamate ligase activity
molecular_function
Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.
[ "PMID:20643647", "PMID:20657015" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-8942575 \"N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG\"" ]
[ "GO:0016879" ]
[]
[]
[]
[ "GO:0016879" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-10T03:20:41Z
false
true
1
GO:0072591
72,591
citrate-L-glutamate ligase activity
molecular_function
Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.
[ "PMID:20657015" ]
null
[]
[]
[]
[]
[]
[ "GO:0016879" ]
[]
[]
[]
[ "GO:0016879" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-10T03:24:26Z
false
true
4
GO:0072592
72,592
oxygen metabolic process
biological_process
The chemical reactions and pathways involving diatomic oxygen (O2).
[ "GOC:mah" ]
null
[ "diatomic oxygen metabolic process", "oxygen metabolism" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-11T10:46:51Z
false
true
5
GO:0072593
72,593
reactive oxygen species metabolic process
biological_process
The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
[ "GOC:mah" ]
null
[ "reactive oxygen species metabolism", "ROS metabolic process" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[ "GO:0008152" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-11T10:50:06Z
false
true
1
GO:0072594
72,594
establishment of protein localization to organelle
biological_process
The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
[ "GOC:mah" ]
null
[ "establishment of protein localisation to organelle" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0045184" ]
[]
[]
[]
[ "GO:0045184" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-14T01:56:51Z
false
true
6
GO:0072595
72,595
maintenance of protein localization in organelle
biological_process
Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
[ "GOC:mah" ]
null
[ "maintenance of protein localisation to organelle", "maintenance of protein localization to organelle" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032507" ]
[ "occurs_in GO:0043226", "part_of GO:0033365" ]
[ "occurs_in", "part_of" ]
[ "GO:0043226", "GO:0033365" ]
[ "GO:0032507", "GO:0033365", "GO:0043226" ]
[ "GO:0045185", "occurs_in GO:0043226" ]
[]
[]
[]
[]
[]
mah
2011-02-14T02:09:13Z
false
true
9
GO:0072598
72,598
protein localization to chloroplast
biological_process
A process in which a protein is transported to, or maintained at, a location in a chloroplast.
[ "GOC:ecd" ]
null
[ "protein localisation to chloroplast" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0033365" ]
[]
[]
[]
[ "GO:0033365" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-14T02:20:30Z
false
true
9
GO:0072599
72,599
establishment of protein localization to endoplasmic reticulum
biological_process
The directed movement of a protein to a specific location in the endoplasmic reticulum.
[ "GOC:mah" ]
null
[ "establishment of protein localisation to endoplasmic reticulum", "establishment of protein localisation to ER", "establishment of protein localization in endoplasmic reticulum", "establishment of protein localization to ER" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0072594" ]
[]
[]
[]
[ "GO:0072594" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-14T02:23:41Z
false
true
7
GO:0072627
72,627
interleukin-28A production
biological_process
The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:15546383" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "IL-28A production", "IL28A production", "interferon lambda 2 production", "interleukin-28A secretion" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[ "GO:0072628" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0034343" ]
[]
[]
[]
[ "GO:0034343" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
4
GO:0072629
72,629
interleukin-28B production
biological_process
The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:15546383" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "IL-28B production", "IL28B production", "interferon lambda 3 production", "interleukin-28B secretion" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[ "GO:0072630" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0034343" ]
[]
[]
[]
[ "GO:0034343" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
2
GO:0072631
72,631
interleukin-29 production
biological_process
The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:15546383" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "IL-29 production", "IL29 production", "interferon lambda 1 production", "interleukin-29 secretion" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[ "GO:0072632" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0034343" ]
[]
[]
[]
[ "GO:0034343" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0072633
72,633
interleukin-30 production
biological_process
The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:30328794" ]
null
[ "IL-30 production", "interleukin-30 complex production", "interleukin-30 secretion" ]
[ "EXACT", "EXACT", "NARROW" ]
[ "GO:0072634" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0001816" ]
[]
[]
[]
[ "GO:0001816" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0072635
72,635
interleukin-31 production
biological_process
The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:30328794" ]
null
[ "IL-31 production", "interleukin-31 secretion" ]
[ "EXACT", "NARROW" ]
[ "GO:0072636" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0001816" ]
[]
[]
[]
[ "GO:0001816" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0072637
72,637
interleukin-32 production
biological_process
The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:23729669" ]
null
[ "IL-32 production", "IL32 production", "interleukin-32 biosynthetic process", "interleukin-32 secretion", "NK4 production", "TAIF production" ]
[ "EXACT", "EXACT", "NARROW", "NARROW", "NARROW", "NARROW" ]
[ "GO:0072638", "GO:0150188" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0001816" ]
[]
[]
[]
[ "GO:0001816" ]
[]
[]
[]
[]
[]
[]
bc
2020-02-21T10:26:40Z
false
true
1
GO:0072639
72,639
interleukin-33 production
biological_process
The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:29778524" ]
null
[ "C9orf26 production", "IL-33 production", "IL1F11 production", "IL33 production", "interleukin-33 biosynthetic process", "interleukin-33 secretion", "NF-HEV production" ]
[ "NARROW", "EXACT", "NARROW", "EXACT", "NARROW", "NARROW", "EXACT" ]
[ "GO:0072640", "GO:0150126" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0001816" ]
[]
[]
[]
[ "GO:0001816" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
5
GO:0072645
72,645
interferon-delta production
biological_process
The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:15546383" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "IFN-delta production", "IFND production", "interferon-delta secretion" ]
[ "EXACT", "EXACT", "NARROW" ]
[ "GO:0072646" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0032606" ]
[]
[]
[]
[ "GO:0032606" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
6
GO:0072649
72,649
interferon-kappa production
biological_process
The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:15546383" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "IFN-kappa production", "IFNK production", "interferon-kappa secretion" ]
[ "EXACT", "EXACT", "NARROW" ]
[ "GO:0072650" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0032606" ]
[]
[]
[]
[ "GO:0032606" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
9
GO:0072651
72,651
interferon-tau production
biological_process
The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:15546383" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "IFN-tau production", "IFN-tau secretion", "IFNT production", "interferon-tau secretion" ]
[ "EXACT", "EXACT", "EXACT", "NARROW" ]
[ "GO:0072652" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0032606" ]
[]
[]
[]
[ "GO:0032606" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0072653
72,653
interferon-omega production
biological_process
The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
[ "GOC:BHF", "GOC:mah", "PMID:15546383" ]
Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms.
[ "IFN-omega production", "IFNW production", "interferon-omega secretion" ]
[ "EXACT", "EXACT", "NARROW" ]
[ "GO:0072654" ]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0032606" ]
[]
[]
[]
[ "GO:0032606" ]
[]
[]
[]
[]
[]
[]
null
null
false
true
3
GO:0072655
72,655
obsolete establishment of protein localization to mitochondrion
biological_process
OBSOLETE. The directed movement of a protein to the mitochondrion or a part of the mitochondrion.
[ "GOC:mah" ]
The reason for obsoletion is that this term was added in error.
[ "establishment of protein localisation to mitochondrion", "establishment of protein localization in mitochondrion" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0070585" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30349\" xsd:anyURI" ]
mah
2011-02-14T02:28:54Z
true
true
7
GO:0072656
72,656
maintenance of protein location in mitochondrion
biological_process
Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0072595" ]
[ "occurs_in GO:0005739", "part_of GO:0070585" ]
[ "occurs_in", "part_of" ]
[ "GO:0005739", "GO:0070585" ]
[ "GO:0005739", "GO:0070585", "GO:0072595" ]
[ "GO:0045185", "occurs_in GO:0005739" ]
[]
[]
[]
[]
[]
mah
2011-02-14T02:30:43Z
false
true
1
GO:0072657
72,657
protein localization to membrane
biological_process
A process in which a protein is transported to, or maintained in, a specific location in a membrane.
[ "GOC:mah" ]
null
[ "protein localisation in membrane", "protein localization in membrane" ]
[ "EXACT", "EXACT" ]
[]
[ "goslim_prokaryote" ]
[]
[ "GO:0008104", "GO:0051668" ]
[]
[]
[]
[ "GO:0008104", "GO:0051668" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-14T02:35:18Z
false
true
1
GO:0072658
72,658
maintenance of protein location in membrane
biological_process
Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0032507" ]
[ "part_of GO:0072657" ]
[ "part_of" ]
[ "GO:0072657" ]
[ "GO:0032507", "GO:0072657" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-14T02:39:41Z
false
true
9
GO:0072659
72,659
protein localization to plasma membrane
biological_process
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
[ "GOC:mah" ]
null
[ "protein localisation in plasma membrane", "protein localization in plasma membrane", "protein targeting to plasma membrane", "protein-plasma membrane targeting" ]
[ "RELATED", "RELATED", "RELATED", "RELATED" ]
[ "GO:0072661", "GO:0090002" ]
[ "goslim_generic", "goslim_pombe" ]
[]
[ "GO:0072657", "GO:1990778" ]
[]
[]
[]
[ "GO:0072657", "GO:1990778" ]
[]
[]
[]
[]
[]
[]
tb
2009-07-10T10:29:23Z
false
true
4
GO:0072660
72,660
maintenance of protein location in plasma membrane
biological_process
Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere.
[ "GOC:mah" ]
null
[]
[]
[]
[]
[]
[ "GO:0072658" ]
[ "part_of GO:0072659" ]
[ "part_of" ]
[ "GO:0072659" ]
[ "GO:0072658", "GO:0072659" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-14T02:46:08Z
false
true
8
GO:0072662
72,662
protein localization to peroxisome
biological_process
A process in which a protein is transported to, or maintained at, a location in a peroxisome.
[ "GOC:ecd" ]
null
[ "protein localisation to peroxisome" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007031", "GO:0033365" ]
[]
[]
[]
[ "GO:0007031", "GO:0033365" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-14T02:50:04Z
false
true
2
GO:0072663
72,663
establishment of protein localization to peroxisome
biological_process
The directed movement of a protein to a specific location in a peroxisome.
[ "GOC:mah" ]
null
[ "establishment of protein localisation to peroxisome" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0072594" ]
[]
[]
[]
[ "GO:0072594" ]
[]
[]
[]
[]
[]
[]
mah
2011-02-14T02:50:36Z
false
true
1