go_id string | go_numeric_id int64 | name string | namespace string | definition string | definition_xrefs list | comment string | synonyms list | synonym_scopes list | alt_ids list | subsets list | xrefs list | is_a_ids list | relationship_edges list | relationship_types list | relationship_target_ids list | parent_ids list | intersection_of list | union_of list | disjoint_from list | replaced_by list | consider list | property_values list | created_by string | creation_date string | is_obsolete bool | in_go_basic bool | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GO:0160286 | 160,286 | queuosine transmembrane transporter activity | molecular_function | Enables the transfer of queuosine from one side of a membrane to the other according to the reaction: queuosine(out) = queuosine(in). | [
"PMID:40526720",
"RHEA:85683"
] | null | [] | [] | [] | [] | [
"RHEA:85683"
] | [
"GO:0005337"
] | [
"part_of GO:0160287"
] | [
"part_of"
] | [
"GO:0160287"
] | [
"GO:0005337",
"GO:0160287"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch RHEA:85683",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30470\" xsd:anyURI"
] | rynl | 2025-06-27T00:30:53Z | false | true | 4 |
GO:0160287 | 160,287 | queuosine import across plasma membrane | biological_process | The directed movement of queuosine from outside of a cell, across the plasma membrane and into the cytosol. | [
"PMID:40526720"
] | null | [] | [] | [] | [] | [] | [
"GO:0098739",
"GO:1901642"
] | [] | [] | [] | [
"GO:0098739",
"GO:1901642"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30470\" xsd:anyURI"
] | rynl | 2025-06-27T00:35:07Z | false | true | 1 |
GO:0160288 | 160,288 | cytoplasmic side of trans-Golgi cisterna membrane | cellular_component | The leaflet of the trans-Golgi cisternae membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it. This is the site where vesicle formation, and cargo sorting towards post-Golgi destinations such as endosomes, lysosomes and the plasma membrane occur. | [
"PMID:23913272",
"PMID:34597626",
"PMID:37566051"
] | null | [
"cytoplasmic face of Golgi trans cisterna membrane",
"cytoplasmic leaflet of Golgi trans cisterna membrane",
"cytoplasmic side of Golgi trans cisternae membrane"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0098562"
] | [
"part_of GO:1990676"
] | [
"part_of"
] | [
"GO:1990676"
] | [
"GO:0098562",
"GO:1990676"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30509\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31515\" xsd:anyURI"
] | rynl | 2025-06-27T05:51:59Z | false | true | 8 |
GO:0160289 | 160,289 | lumenal side of trans-Golgi cisternae membrane | cellular_component | The leaflet of the trans-Golgi cisternae membrane that faces the Golgi lumen, including any protein embedded in, attached to, or peripherally associated with it. This is the site where the final steps of glycan processing, proteolytic modification, and cargo maturation prior to sorting at the trans-Golgi network occur. | [
"PMID:34597626",
"PMID:38307322",
"PMID:6121819"
] | null | [
"lumenal face of trans-Golgi cisternae membrane",
"lumenal leaflet of trans-Golgi cisternae membrane",
"lumenal side of Golgi trans cisternae membrane"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0098576"
] | [
"part_of GO:1990676"
] | [
"part_of"
] | [
"GO:1990676"
] | [
"GO:0098576",
"GO:1990676"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30510\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31515\" xsd:anyURI"
] | rynl | 2025-06-27T06:11:48Z | false | true | 1 |
GO:0160290 | 160,290 | 2-oxoglutarate-dependent tRNA 5-methylcytidine formyltransferase activity | molecular_function | Catalysis of the reaction: 5-methylcytidine(34) in mitochondrial tRNA(Met) + 2 2-oxoglutarate + 2 O2 = 5-formylcytidine(34) in mitochondrial tRNA(Met) + 2 succinate + 2 CO2 + H2O. | [
"PMID:27497299",
"PMID:28472312",
"RHEA:54144"
] | null | [] | [] | [] | [] | [
"RHEA:54144"
] | [
"GO:0016706",
"GO:0140101"
] | [] | [] | [] | [
"GO:0016706",
"GO:0140101"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch RHEA:54144"
] | rynl | 2025-07-05T00:30:16Z | false | true | 4 |
GO:0160291 | 160,291 | phosphatidylinositol-4-phosphate-cholesterol exchange activity | molecular_function | Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + cholesterol(in) = 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + cholesterol(out). This reaction results in the exchange of cholesterol for phosphatidylinositol-4-phosphate (PI(4)P) between membranes. | [
"PMID:24209621",
"PMID:29596003",
"RHEA:84179"
] | null | [] | [] | [] | [] | [
"RHEA:84179"
] | [
"GO:0120014",
"GO:0120020",
"GO:7770011"
] | [] | [] | [] | [
"GO:0120014",
"GO:0120020",
"GO:7770011"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch RHEA:84179",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27059\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30432\" xsd:anyURI"
] | rynl | 2025-07-16T17:44:49Z | false | true | 5 |
GO:0160292 | 160,292 | sodium-translocating NADH:quinone reductase complex | cellular_component | A bacterial protein complex consisting of six subunits, NqrABCDEF, encoded by the nqr operon, which catalyzes electron transfer from NADH to ubiquinone in the respiratory chain coupled with the transport of sodium ions from the cytoplasm to the periplasm. | [
"PMID:38955304"
] | null | [
"Na(+)-translocating NADH-quinone reductase complex",
"Na+-NQR complex"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0032991"
] | [] | [] | [] | [
"GO:0032991"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30612\" xsd:anyURI"
] | rynl | 2025-07-25T22:59:20Z | false | true | 3 |
GO:0160294 | 160,294 | clathrin- and caveolae-independent endocytosis | biological_process | An endocytosis process that internalizes cargo via small, non-coated vesicles (~40-80 nm) without relying on clathrin or caveolin and can be dynamin-dependent or dynamin-independent. | [
"PMID:15668298",
"PMID:31976201"
] | null | [] | [] | [] | [] | [] | [
"GO:0006897"
] | [] | [] | [] | [
"GO:0006897"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30667\" xsd:anyURI"
] | rynl | 2025-08-04T16:38:59Z | false | true | 8 |
GO:0160295 | 160,295 | mitochondrial complex I intermediate assembly complex | cellular_component | A protein complex involved in mitochondrial respiratory chain complex I (MCI) assembly. The mitochondrial complex I intermediate assembly (MCIA) complex is an inner mitochondrial membrane complex required for the aggregation, arrangement and bonding together of the subunits of the ND2-module of MCI. In humans, the MCIA... | [
"PMID:32320651"
] | null | [
"MCIA complex",
"mitochondrial CI assembly complex"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0098800"
] | [] | [] | [] | [
"GO:0098800"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30671\" xsd:anyURI"
] | rynl | 2025-08-05T23:37:22Z | false | true | 8 |
GO:0160297 | 160,297 | IRES-mediated translation initiation factor activity | molecular_function | A translation initiation factor activity that enables interaction with internal ribosome entry sites (IRESs) located within mRNA, promoting ribosome recruitment and assembly at internal initiation sites and translation initiation independent of the 5' cap structure. | [
"PMID:21118130",
"PMID:31913484"
] | null | [] | [] | [] | [] | [] | [
"GO:0003743"
] | [] | [] | [] | [
"GO:0003743"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30674\" xsd:anyURI"
] | rynl | 2025-08-11T18:54:21Z | false | true | 6 |
GO:0160298 | 160,298 | pyridinol guanylyltransferase activity | molecular_function | Catalysis of the reaction: 6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol + GTP + H+ = guanylylpyridinol + diphosphate. | [
"PMID:24249552",
"RHEA:85479"
] | null | [] | [] | [] | [] | [
"EC:2.7.7.109",
"KEGG_REACTION:R13518",
"RHEA:85479"
] | [
"GO:0070568"
] | [] | [] | [] | [
"GO:0070568"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch EC:2.7.7.109",
"skos:exactMatch RHEA:85479",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30718\" xsd:anyURI"
] | rynl | 2025-08-21T00:46:39Z | false | true | 8 |
GO:0160301 | 160,301 | guanylylpyridinol adenylase activity | molecular_function | Catalysis of the reaction: guanylylpyridinol + ATP + H+ = guanylylpyridinol-AMP + diphosphate. | [
"PMID:25882909",
"RHEA:85487"
] | null | [] | [] | [] | [] | [
"EC:2.7.7.110",
"KEGG_REACTION:R13520",
"RHEA:85487"
] | [
"GO:0016779"
] | [] | [] | [] | [
"GO:0016779"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch EC:2.7.7.110",
"skos:exactMatch RHEA:85487",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30720\" xsd:anyURI"
] | rynl | 2025-08-21T22:49:37Z | false | true | 7 |
GO:0160302 | 160,302 | 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity | molecular_function | Catalysis of the reaction: 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol + S-adenosyl-L-methionine = 6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol + S-adenosyl-L-homocysteine + H+. | [
"PMID:27391308",
"RHEA:85483"
] | null | [] | [] | [] | [] | [
"KEGG_REACTION:R13499",
"RHEA:85483"
] | [
"GO:0008168"
] | [] | [] | [] | [
"GO:0008168"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch RHEA:85483",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30721\" xsd:anyURI"
] | rynl | 2025-08-21T23:15:13Z | false | true | 5 |
GO:0160303 | 160,303 | protein secretion by the type IX secretion system | biological_process | The process by which proteins are transported from the periplasmic space across the outer membrane of Bacteroidota bacteria via the type IX secretion system (T9SS). | [
"PMID:19966289",
"PMID:37043368",
"PMID:40490843"
] | null | [
"Por secretion system",
"PorSS",
"T9SS"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0009306",
"GO:0071806"
] | [] | [] | [] | [
"GO:0009306",
"GO:0071806"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30722\" xsd:anyURI"
] | rynl | 2025-08-22T00:30:40Z | false | true | 3 |
GO:0160304 | 160,304 | 4-vinylphenol methyltransferase activity | molecular_function | Catalysis of the reaction: 4-vinylphenol + S-adenosyl-L-methionine = 4-vinylanisole + S-adenosyl-L-homocysteine + H+. | [
"PMID:40562929",
"RHEA:86075"
] | null | [] | [] | [] | [] | [
"RHEA:86075"
] | [
"GO:0008171",
"GO:0008757"
] | [] | [] | [] | [
"GO:0008171",
"GO:0008757"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch RHEA:86075",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30708\" xsd:anyURI"
] | rynl | 2025-08-23T00:16:21Z | false | true | 4 |
GO:0160305 | 160,305 | 4-vinylanisole biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of 4-vinylanisole. 4-vinylanisole derived from food plant phenylalanin is the aggregation pheromone specifically released by gregarious migratory locusts. | [
"PMID:40562929"
] | null | [] | [] | [] | [] | [] | [
"GO:0042537",
"GO:0042811",
"GO:1901503"
] | [] | [] | [] | [
"GO:0042537",
"GO:0042811",
"GO:1901503"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30708\" xsd:anyURI"
] | rynl | 2025-08-23T00:32:14Z | false | true | 3 |
GO:0160306 | 160,306 | swarm social behavior | biological_process | A social behavior in which multiple individuals of the same animal species coordinate their movement in close spatial proximity, forming a dynamic aggregation typically characterized by collective motion, cohesion, and mutual responsiveness among members of the group. | [
"DOI:10.1007/s13592-013-0253-2",
"PMID:23740485",
"PMID:32788724"
] | null | [
"swarming behavior"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0035176"
] | [] | [] | [] | [
"GO:0035176"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30708\" xsd:anyURI"
] | rynl | 2025-08-27T22:14:18Z | false | true | 5 |
GO:0160307 | 160,307 | protein biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of protein. | [
"Wikipedia:Protein_biosynthesis"
] | null | [
"protein biosynthesis",
"protein synthesis"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0009059",
"GO:0019538"
] | [
"has_part GO:0043039",
"part_of GO:0010467"
] | [
"has_part",
"part_of"
] | [
"GO:0043039",
"GO:0010467"
] | [
"GO:0009059",
"GO:0010467",
"GO:0019538",
"GO:0043039"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15375\" xsd:anyURI"
] | rynl | 2025-09-29T23:16:32Z | false | true | 6 |
GO:0160308 | 160,308 | succinate dehydrogenase (FAD) activity | molecular_function | Catalysis of the reaction: FAD + succinate + H+ = fumarate + FADH2. | [
"RHEA:30343",
"WIKIPEDIA:SDHA"
] | null | [] | [] | [] | [] | [
"RHEA:30343"
] | [
"GO:0000104"
] | [] | [] | [] | [
"GO:0000104"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch RHEA:30343",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30805\" xsd:anyURI"
] | rynl | 2025-10-20T18:32:39Z | false | true | 9 |
GO:0160309 | 160,309 | commander complex | cellular_component | A protein complex that promotes the recycling of internalized transmembrane proteins from endosomes back to the plasma membrane. The commander complex consists of the CCC (COMMD/CCDC22/CCDC93) subcomplex and the retriever subcomplex. In human, the CCC subcomplex consists of COMMD1, COMMD2, COMMD3, COMMD4, COMMD5, COMMD... | [
"PMID:28892079",
"PMID:37172566"
] | null | [] | [] | [] | [] | [] | [
"GO:0032991"
] | [] | [] | [] | [
"GO:0032991"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31090\" xsd:anyURI"
] | rynl | 2025-11-19T23:57:27Z | false | true | 8 |
GO:0160310 | 160,310 | dopamine loading into synaptic vesicle | biological_process | The active transport of dopamine neurotransmitters into a synaptic vesicle. | [
"PMID:29666153"
] | null | [] | [] | [] | [] | [] | [
"GO:0015872",
"GO:0098700"
] | [] | [] | [] | [
"GO:0015872",
"GO:0098700"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31143\" xsd:anyURI"
] | rynl | 2025-12-02T22:02:35Z | false | true | 3 |
GO:0160311 | 160,311 | tyramine loading into synaptic vesicle | biological_process | The active transport of tyramine neurotransmitters into a synaptic vesicle. | [
"PMID:15849736",
"PMID:9870940"
] | null | [] | [] | [] | [] | [] | [
"GO:0098700",
"GO:7770032"
] | [] | [] | [] | [
"GO:0098700",
"GO:7770032"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31143\" xsd:anyURI"
] | rynl | 2025-12-02T23:16:14Z | false | true | 1 |
GO:0160313 | 160,313 | endosomal intralumenal vesicle | cellular_component | A membrane-bounded vesicle that is located within the lumen of an endosome. | [
"PMID:21878991",
"PMID:31854087"
] | null | [
"ILV"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0031410"
] | [
"part_of GO:0005768"
] | [
"part_of"
] | [
"GO:0005768"
] | [
"GO:0005768",
"GO:0031410"
] | [
"GO:0097708",
"part_of GO:0005768"
] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31158\" xsd:anyURI"
] | rynl | 2025-12-04T17:58:06Z | false | true | 6 |
GO:0160314 | 160,314 | endosomal intralumenal vesicle membrane | cellular_component | The lipid bilayer surrounding an intraluminal vesicle within an endososome. | [
"PMID:31854087",
"PMID:38706230"
] | null | [
"endosome ILV membrane",
"endosome internal vesicle membrane"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0030659",
"GO:0098588"
] | [
"part_of GO:0160313"
] | [
"part_of"
] | [
"GO:0160313"
] | [
"GO:0030659",
"GO:0098588",
"GO:0160313"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31159\" xsd:anyURI"
] | rynl | 2025-12-08T16:52:03Z | false | true | 1 |
GO:0160315 | 160,315 | endosomal intralumenal vesicle lumen | cellular_component | The volume enclosed by the membrane of an intraluminal vesicle within an endosome. | [
"PMID:31854087",
"PMID:38706230"
] | null | [
"endosome ILV lumen",
"endosome internal vesicle lumen"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0070013"
] | [
"part_of GO:0160313"
] | [
"part_of"
] | [
"GO:0160313"
] | [
"GO:0070013",
"GO:0160313"
] | [
"GO:0031974",
"part_of GO:0160313"
] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31159\" xsd:anyURI"
] | rynl | 2025-12-08T17:33:35Z | false | true | 9 |
GO:0160316 | 160,316 | endolysosomal intralumenal vesicle | cellular_component | A membrane-bounded vesicle that is located within the lumen of an endolysosome. | [
"PMID:31854087",
"PMID:38706230"
] | null | [
"endolysosomal ILV"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0160313"
] | [
"part_of GO:0036019"
] | [
"part_of"
] | [
"GO:0036019"
] | [
"GO:0036019",
"GO:0160313"
] | [
"GO:0097708",
"part_of GO:0036019"
] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31158\" xsd:anyURI"
] | rynl | 2025-12-24T00:02:56Z | false | true | 5 |
GO:0160317 | 160,317 | endolysosomal intralumenal vesicle membrane | cellular_component | The lipid bilayer surrounding an intraluminal vesicle within an endolysosome. | [
"PMID:31854087",
"PMID:38706230"
] | null | [
"endolysosome ILV membrane",
"endolysosome internal vesicle membrane"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0160314"
] | [
"part_of GO:0160316"
] | [
"part_of"
] | [
"GO:0160316"
] | [
"GO:0160314",
"GO:0160316"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31159\" xsd:anyURI"
] | rynl | 2025-12-24T00:06:07Z | false | true | 4 |
GO:0160318 | 160,318 | endolysosomal intralumenal vesicle lumen | cellular_component | The volume enclosed by the membrane of an intraluminal vesicle within an endolysosome. | [
"PMID:31854087",
"PMID:38706230"
] | null | [
"endolysosome ILV lumen",
"endolysosome internal vesicle lumen"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0005775",
"GO:0160315"
] | [
"part_of GO:0160316"
] | [
"part_of"
] | [
"GO:0160316"
] | [
"GO:0005775",
"GO:0160315",
"GO:0160316"
] | [
"GO:0031974",
"part_of GO:0160316"
] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31160\" xsd:anyURI"
] | rynl | 2025-12-24T00:18:06Z | false | true | 3 |
GO:0160319 | 160,319 | lipoyl-dependent peroxiredoxin activity | molecular_function | Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + a hydroperoxide = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + an alcohol + H2O. | [
"EC:1.11.1.28",
"RHEA:62636"
] | null | [] | [] | [] | [] | [
"EC:1.11.1.28",
"RHEA:62636"
] | [
"GO:0004601"
] | [] | [] | [] | [
"GO:0004601"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch EC:1.11.1.28",
"skos:exactMatch RHEA:62636",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31239\" xsd:anyURI"
] | rynl | 2025-12-29T00:52:44Z | false | true | 9 |
GO:0160320 | 160,320 | obsolete protein-tyrosine iodotransferase activity | molecular_function | OBSOLETE. Catalysis of the reaction: [thyroglobulin]-L-tyrosine + iodide + H2O2 + H+ = [thyroglobulin]-3-iodo-L-tyrosine + 2 H2O and [thyroglobulin]-3-iodo-L-tyrosine + iodide + H2O2 + H+ = [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O. | [
"PMID:36537574",
"PMID:8651700"
] | The reason for obsoletion is that the reactions covered by this term (RHEA:48956 and RHEA:48960) are now subsumed by the updated GO:0004447 (iodide peroxidase activity), which covers all 5 thyroid peroxidase reactions. | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0004447"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30596\" xsd:anyURI"
] | null | null | true | true | 7 |
GO:0170002 | 170,002 | halotropism | biological_process | A sodium-specific negative tropism that is crucial for surviving and thriving under high salinity. | [
"PMID:36243013"
] | null | [
"root halotropism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0009606"
] | [] | [] | [] | [
"GO:0009606"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24300\" xsd:anyURI"
] | ew | 2022-11-01T17:36:17Z | false | true | 3 |
GO:0170004 | 170,004 | lipoate transmembrane transporter activity | molecular_function | Enables the transfer of lipoate from one side of a membrane to the other. | [
"PMID:20980265",
"PMID:25971966"
] | null | [] | [] | [] | [] | [] | [
"GO:0022857"
] | [] | [] | [] | [
"GO:0022857"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25332\" xsd:anyURI"
] | ew | 2023-06-06T17:38:04Z | false | true | 2 |
GO:0170005 | 170,005 | cyclic nucleotide phosphodiesterase activator activity | molecular_function | Binds to and increases the activity of cyclic nucleotide phosphodiesterase. | [
"PMID:6087882",
"PMID:6259174",
"PMID:6667031"
] | null | [] | [] | [] | [] | [] | [
"GO:0008047"
] | [
"positively_regulates GO:0004112"
] | [
"positively_regulates"
] | [
"GO:0004112"
] | [
"GO:0004112",
"GO:0008047"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24706\" xsd:anyURI"
] | ew | 2023-01-24T19:49:38Z | false | true | 2 |
GO:0170006 | 170,006 | lipoate transmembrane transport | biological_process | The process in which lipoate is transported across a membrane. | [
"PMID:20980265",
"PMID:25971966"
] | null | [] | [] | [] | [] | [] | [
"GO:0055085"
] | [] | [] | [] | [
"GO:0055085"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25332\" xsd:anyURI"
] | ew | 2023-06-06T17:40:56Z | false | true | 3 |
GO:0170007 | 170,007 | endoplasmic reticulum-lipid droplet tether activity | molecular_function | The binding activity of a molecule that brings together a lipid droplet with an endoplasmic reticulum membrane, via membrane lipid binding, to establish membrane contact sites and mediate exchange and communication. | [
"PMID:35389430"
] | null | [] | [] | [] | [] | [
"Reactome:R-HSA-8857686 \"FITM2 binds TAGs\"",
"Reactome:R-HSA-9942190 \"FITM1 binds TAGs\""
] | [
"GO:0043495"
] | [] | [] | [] | [
"GO:0043495"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25428\" xsd:anyURI"
] | ew | 2023-06-06T18:21:51Z | false | true | 2 |
GO:0170008 | 170,008 | mRNA phosphatase activator activity | molecular_function | Binds to and increases the activity of mRNA phosphatase. | [
"PMID:22323607"
] | null | [] | [] | [] | [] | [] | [
"GO:0008047"
] | [
"positively_regulates GO:0140818"
] | [
"positively_regulates"
] | [
"GO:0140818"
] | [
"GO:0008047",
"GO:0140818"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24720\" xsd:anyURI"
] | ew | 2023-01-25T18:31:14Z | false | true | 9 |
GO:0170009 | 170,009 | endoplasmic reticulum-organelle membrane tether activity | molecular_function | The binding activity of a molecule that brings together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain membrane contact sites and mediate organelle exchange and communication. | [
"PMID:29858488"
] | null | [] | [] | [] | [] | [] | [
"GO:0043495"
] | [] | [] | [] | [
"GO:0043495"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25429\" xsd:anyURI"
] | ew | 2023-06-29T16:28:28Z | false | true | 9 |
GO:0170010 | 170,010 | nonsense-mediated decay complex | cellular_component | A highly conserved protein complex that recognises and elicits the rapid degradation of mRNAs in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction. | [
"GOC:lnp",
"PMID:1569946",
"PMID:29282598",
"PMID:9032286"
] | null | [
"Upf complex"
] | [
"EXACT"
] | [] | [] | [
"IntAct:EBI-16420380"
] | [
"GO:1902494"
] | [] | [] | [] | [
"GO:1902494"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15365\" xsd:anyURI"
] | ew | 2023-02-02T16:55:18Z | false | true | 9 |
GO:0170011 | 170,011 | stalled ribosome sensor activity | molecular_function | A molecule that recognizes stalled ribosomes and initiates a signaling response. | [
"PMID:32289254",
"PMID:32610081",
"PMID:36638793"
] | null | [] | [] | [] | [] | [] | [
"GO:0140299"
] | [
"has_part GO:0043022"
] | [
"has_part"
] | [
"GO:0043022"
] | [
"GO:0043022",
"GO:0140299"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24865\" xsd:anyURI"
] | ew | 2023-02-09T20:20:22Z | false | true | 1 |
GO:0170012 | 170,012 | histone H3K18 decrotonylase activity | molecular_function | Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone H3 position 18] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone H3] + nicotinamide. | [
"PMID:34927582"
] | Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro... | [] | [] | [] | [] | [] | [
"GO:0160012"
] | [] | [] | [] | [
"GO:0160012"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch RHEA:69332",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24466\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI"
] | ew | 2023-02-09T20:55:09Z | false | true | 1 |
GO:0170013 | 170,013 | channel complex | cellular_component | A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient. | [
"PMID:10839820"
] | null | [] | [] | [] | [] | [] | [
"GO:0098796"
] | [] | [] | [] | [
"GO:0098796"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20026\" xsd:anyURI"
] | ew | 2023-03-01T01:48:30Z | false | true | 1 |
GO:0170014 | 170,014 | ankyrin-1 complex | cellular_component | A complex composed of ANK1, RHCE, RHAG, SLC4A1, EPB42, GYPA, GYPB and AQP1, that functions in the stability and shape of the erythrocyte membrane in human. | [
"PMID:35835865"
] | null | [
"ankyrin complex",
"erythrocyte ankyrin-1 complex"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0098796"
] | [] | [] | [] | [
"GO:0098796"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24929\" xsd:anyURI"
] | ew | 2023-03-01T18:24:19Z | false | true | 5 |
GO:0170015 | 170,015 | carbon dioxide receptor activity | molecular_function | Combining with carbon dioxide to initiate a change in cell activity. | [
"PMID:24240097"
] | null | [] | [] | [] | [] | [] | [
"GO:0038023"
] | [] | [] | [] | [
"GO:0038023"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24994\" xsd:anyURI"
] | ew | 2023-03-08T01:05:36Z | false | true | 1 |
GO:0170016 | 170,016 | endoplasmic reticulum-endosome tether activity | molecular_function | The binding activity of a molecule that brings together an endosome and an ER membrane either via membrane lipid binding or by interacting with an endosome protein, to establish and facilitate organelle exchange. | [
"PMID:33124732"
] | null | [] | [] | [] | [] | [] | [
"GO:0170009"
] | [] | [] | [] | [
"GO:0170009"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25429\" xsd:anyURI"
] | ew | 2023-06-29T16:31:41Z | false | true | 5 |
GO:0170020 | 170,020 | ionotropic olfactory receptor activity | molecular_function | Enables the transmembrane transfer of an ion by a channel that opens when a specific odorant has been bound by the channel complex or one of its constituent parts. | [
"PMID:21857978",
"PMID:24661599"
] | null | [] | [] | [] | [] | [] | [
"GO:0004984",
"GO:0015276"
] | [] | [] | [] | [
"GO:0004984",
"GO:0015276"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25525\" xsd:anyURI"
] | ew | 2023-06-30T17:49:23Z | false | true | 9 |
GO:0170021 | 170,021 | ionotropic taste receptor activity | molecular_function | Enables the transmembrane transfer of an ion by a channel that opens when a soluble compound has been bound by the channel complex or one of its constituent parts. | [
"PMID:36828965"
] | null | [] | [] | [] | [] | [] | [
"GO:0008527",
"GO:0015276"
] | [] | [] | [] | [
"GO:0008527",
"GO:0015276"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25533\" xsd:anyURI"
] | ew | 2023-07-03T19:05:36Z | false | true | 2 |
GO:0170022 | 170,022 | ionotropic bitter taste receptor activity | molecular_function | Enables the transmembrane transfer of an ion by a channel that opens when a specific bitter compound has been bound by the channel complex or one of its constituent parts. | [
"PMID:21262465"
] | null | [] | [] | [] | [] | [] | [
"GO:0170021"
] | [] | [] | [] | [
"GO:0170021"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25533\" xsd:anyURI"
] | ew | 2023-07-03T19:22:08Z | false | true | 8 |
GO:0170023 | 170,023 | ionotropic sweet taste receptor activity | molecular_function | Enables the transmembrane transfer of an ion by a channel that opens when a specific soluble sweet compound has been bound by the channel complex or one of its constituent parts. | [
"PMID:24474785"
] | null | [] | [] | [] | [] | [] | [
"GO:0170021"
] | [] | [] | [] | [
"GO:0170021"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25533\" xsd:anyURI"
] | ew | 2023-07-03T19:24:28Z | false | true | 6 |
GO:0170027 | 170,027 | SKA complex | cellular_component | An outer kinetochore complex involved in the attachment of microtubule ends to the chromosomes during mitosis. In humans, it contains the subunits SKA1, SKA2 and SKA3. | [
"PMID:19289083",
"PMID:22483620"
] | null | [
"SKA1 complex"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0032991"
] | [
"part_of GO:0000940"
] | [
"part_of"
] | [
"GO:0000940"
] | [
"GO:0000940",
"GO:0032991"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25850\" xsd:anyURI"
] | ew | 2023-08-03T18:42:06Z | false | true | 9 |
GO:0170033 | 170,033 | L-amino acid metabolic process | biological_process | The chemical reactions and pathways involving an L-amino acid. | [
"GOC:edw"
] | null | [
"L-alpha-amino acid metabolism",
"L-amino acid metabolism"
] | [
"EXACT",
"EXACT"
] | [] | [] | [
"Reactome:R-HSA-8963693 \"Aspartate and asparagine metabolism\"",
"Reactome:R-HSA-8964539 \"Glutamate and glutamine metabolism\""
] | [
"GO:1901605"
] | [] | [] | [] | [
"GO:1901605"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI"
] | ew | 2023-11-20T23:41:23Z | false | true | 6 |
GO:0170034 | 170,034 | L-amino acid biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of L-amino acids, the L-enantiomers of amino acids. | [
"GOC:edw"
] | null | [
"L-amino acid anabolism",
"L-amino acid biosynthesis",
"L-amino acid formation",
"L-amino acid synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0170033",
"GO:1901607"
] | [] | [] | [] | [
"GO:0170033",
"GO:1901607"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI"
] | ew | 2023-11-20T23:42:06Z | false | true | 7 |
GO:0170035 | 170,035 | L-amino acid catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of an L-amino acid. | [
"GOC:edw"
] | null | [
"L-amino acid breakdown",
"L-amino acid catabolism",
"L-amino acid degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0170033",
"GO:1901606"
] | [] | [] | [] | [
"GO:0170033",
"GO:1901606"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI"
] | ew | 2023-11-21T00:55:07Z | false | true | 6 |
GO:0170036 | 170,036 | import into the mitochondrion | biological_process | The directed movement of substances from the cytosol into the mitochondrion. | [
"GOC:ew"
] | null | [] | [] | [] | [] | [] | [
"GO:0010496",
"GO:1990542"
] | [] | [] | [] | [
"GO:0010496",
"GO:1990542"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26201\" xsd:anyURI"
] | ew | 2023-11-30T20:56:49Z | false | true | 5 |
GO:0170038 | 170,038 | proteinogenic amino acid biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. | [
"GOC:ew"
] | null | [
"proteinogenic amino acid anabolism",
"proteinogenic amino acid biosynthesis",
"proteinogenic amino acid formation",
"proteinogenic amino acid synthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0046394",
"GO:0170039"
] | [] | [] | [] | [
"GO:0046394",
"GO:0170039"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI"
] | ew | 2023-12-18T16:28:19Z | false | true | 5 |
GO:0170039 | 170,039 | proteinogenic amino acid metabolic process | biological_process | The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. | [
"GOC:ew"
] | null | [
"proteinogenic amino acid metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0006520",
"GO:0019752"
] | [] | [] | [] | [
"GO:0006520",
"GO:0019752"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI"
] | ew | 2023-12-18T17:31:08Z | false | true | 3 |
GO:0170040 | 170,040 | proteinogenic amino acid catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein. | [
"GOC:ew"
] | null | [
"proteinogenic amino acid breakdown",
"proteinogenic amino acid catabolism",
"proteinogenic amino acid degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0046395",
"GO:0170039"
] | [] | [] | [] | [
"GO:0046395",
"GO:0170039"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI"
] | ew | 2023-12-18T17:41:14Z | false | true | 8 |
GO:0170041 | 170,041 | non-proteinogenic amino acid metabolic process | biological_process | The chemical reactions and pathways involving non-proteingenic amino acids. | [
"GOC:ew"
] | null | [
"non-proteinogenic amino acid metabolism"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0006520",
"GO:0019752"
] | [] | [] | [] | [
"GO:0006520",
"GO:0019752"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23269\" xsd:anyURI"
] | ew | 2023-12-18T17:57:55Z | false | true | 3 |
GO:0170043 | 170,043 | non-proteinogenic amino acid biosynthetic process | biological_process | The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids. | [
"GOC:ew"
] | null | [
"non-proteinogenic amino acid anabolism",
"non-proteinogenic amino acid formation",
"non-proteinogenic amino acid synthesis",
"non-proteinogenic biosynthesis"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0046394",
"GO:0170041"
] | [] | [] | [] | [
"GO:0046394",
"GO:0170041"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23269\" xsd:anyURI"
] | ew | 2023-12-18T19:03:08Z | false | true | 5 |
GO:0170044 | 170,044 | non-proteinogenic amino acid catabolic process | biological_process | The chemical reactions and pathways resulting in the breakdown of non-proteinogenic amino acids. | [
"GOC:ew"
] | null | [
"non-proteinogenic amino acid breakdown",
"non-proteinogenic amino acid catabolism",
"non-proteinogenic amino acid degradation"
] | [
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0046395",
"GO:0170041"
] | [] | [] | [] | [
"GO:0046395",
"GO:0170041"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23269\" xsd:anyURI"
] | ew | 2023-12-18T19:27:05Z | false | true | 8 |
GO:0170046 | 170,046 | isopentenyl pyrophosphate import into mitochondrion | biological_process | The process in which isopentenyl pyrophosphate is transported across a membrane into the mitochondrion. | [
"GOC:ew",
"PMID:37813972"
] | null | [] | [] | [] | [] | [] | [
"GO:0015711",
"GO:0015914",
"GO:0032365",
"GO:0170036"
] | [] | [] | [] | [
"GO:0015711",
"GO:0015914",
"GO:0032365",
"GO:0170036"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26285\" xsd:anyURI"
] | ew | 2024-01-10T00:03:13Z | false | true | 2 |
GO:0170047 | 170,047 | virus-like capsid | cellular_component | A protein coat that surrounds nucleic acid to form a structure similar to a virus capsid. Virus-like capsids are non-infectious and are encoded by endogenous (non-viral) genes. Fly and tetrapod Arc (ancestrally-related to retrotransposon Gag) are examples of proteins that can self-assemble into capsid-like structures w... | [
"PMID:29328916"
] | null | [
"virus-like particle"
] | [
"NARROW"
] | [] | [] | [] | [
"GO:0110165"
] | [] | [] | [] | [
"GO:0110165"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26842\" xsd:anyURI"
] | ew | 2024-01-26T21:31:41Z | false | true | 7 |
GO:0170048 | 170,048 | D-alanine import across plasma membrane | biological_process | The directed import of D-alanine from the extracellular region across the plasma membrane and into the cytosol. | [
"PMID:22418438",
"PMID:25425233"
] | null | [
"D-alanine import",
"D-alanine import into cell",
"D-alanine uptake"
] | [
"BROAD",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0042941"
] | [] | [] | [] | [
"GO:0042941"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26844\" xsd:anyURI"
] | ew | 2024-01-26T22:35:49Z | false | true | 7 |
GO:0170049 | 170,049 | box C/D RNP complex | cellular_component | A ribonucleoprotein complex consisting of a box C/D type snRNA and three (Archaea) or four (Eukaryotes) core proteins that have diverse functions, including site-specific methylation of rRNA and processing rRNA. | [
"PMID:28505386",
"PMID:30254138"
] | null | [
"SNORD ribonucleoprotein complex",
"SNORNP"
] | [
"BROAD",
"BROAD"
] | [] | [] | [] | [
"GO:0005732"
] | [] | [] | [] | [
"GO:0005732"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11686\" xsd:anyURI"
] | ew | 2024-02-02T21:26:03Z | false | true | 5 |
GO:0170050 | 170,050 | box C/D methylation guide RNP complex | cellular_component | A ribonucleoprotein complex containing a box C/D type snoRNA and three (Archaea) or four (Eukaryotes) core proteins that is capable of methylation of target RNAs. | [
"PMID:28505386",
"PMID:30254138"
] | null | [] | [] | [] | [] | [] | [
"GO:0170049"
] | [] | [] | [] | [
"GO:0170049"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11686\" xsd:anyURI"
] | ew | 2024-02-02T21:27:11Z | false | true | 6 |
GO:0170051 | 170,051 | box C/D methylation guide scaRNP complex | cellular_component | A ribonucleoprotein complex containing a small CB-specific RNA (scaRNA), with a short sequence motif (GU/UG wobble stem) for CB localization that is capable of methylation of target RNAs. | [
"PMID:27775477"
] | null | [] | [] | [] | [] | [] | [
"GO:0170049"
] | [] | [] | [] | [
"GO:0170049"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11686\" xsd:anyURI"
] | ew | 2024-02-02T21:27:41Z | false | true | 3 |
GO:0170052 | 170,052 | box C/D pre-rRNA cleavage RNP complex | cellular_component | A ribonucleoprotein complex containing a box C/D type RNA that is involved in pre-rRNA cleavage. | [
"PMID:15367679",
"PMID:28505386",
"PMID:30254138"
] | null | [] | [] | [] | [] | [] | [
"GO:0170049"
] | [] | [] | [] | [
"GO:0170049"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11686\" xsd:anyURI"
] | ew | 2024-02-02T21:29:50Z | false | true | 4 |
GO:0170053 | 170,053 | nuclease activator activity | molecular_function | Binds to and increases the activity of a nuclease. | [
"PMID:24736845"
] | null | [] | [] | [] | [] | [] | [
"GO:0008047"
] | [
"positively_regulates GO:0004518"
] | [
"positively_regulates"
] | [
"GO:0004518"
] | [
"GO:0004518",
"GO:0008047"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27178\" xsd:anyURI"
] | ew | 2024-03-05T00:43:33Z | false | true | 6 |
GO:0170054 | 170,054 | ribonuclease activator activity | molecular_function | Binds to and increases the activity of a ribonuclease. | [
"PMID:24736845"
] | null | [
"RNA nuclease activator activity"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0170053"
] | [
"positively_regulates GO:0004540"
] | [
"positively_regulates"
] | [
"GO:0004540"
] | [
"GO:0004540",
"GO:0170053"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27178\" xsd:anyURI"
] | ew | 2024-03-05T00:45:50Z | false | true | 4 |
GO:0170055 | 170,055 | lipid transmembrane transporter activity | molecular_function | Enables the transfer of a lipid from one side of a membrane to the other. | [
"GOC:curators"
] | null | [] | [] | [] | [
"gocheck_do_not_annotate"
] | [] | [
"GO:0022857"
] | [] | [] | [] | [
"GO:0022857"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27252\" xsd:anyURI"
] | ew | 2024-03-15T18:47:58Z | false | true | 2 |
GO:0170056 | 170,056 | cholesterol 7-desaturase [NAD(P)H] activity | molecular_function | Catalysis of the reaction: cholesterol + H+ + NAD(P)H + O2 = 7-dehydrocholesterol + 2 H2O + NAD(P)+. | [
"EC:1.14.19.21",
"PMID:21632547",
"PMID:31521708"
] | null | [
"C-7 cholesterol dehydrogenase",
"cholesterol 7,8-dehydrogenase"
] | [
"EXACT",
"EXACT"
] | [] | [] | [
"EC:1.14.19.21",
"MetaCyc:RXN-16379",
"RHEA:45024",
"RHEA:51644"
] | [
"GO:0070704"
] | [] | [] | [] | [
"GO:0070704"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch EC:1.14.19.21",
"skos:exactMatch MetaCyc:RXN-16379",
"skos:narrowMatch RHEA:45024",
"skos:narrowMatch RHEA:51644",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27381\" xsd:anyURI"
] | ew | 2024-03-26T16:57:18Z | false | true | 2 |
GO:0170057 | 170,057 | RNA ligase (GTP) activity | molecular_function | Catalysis of the joining of an RNA with 3'-phosphate or 2',3'-cyclic-phosphate ends to an RNA with 5'-hydroxy ends according to either (i) a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP; or (ii) a 3'-end 2',3'-cyclophospho-... | [
"EC:6.5.1.8",
"PMID:21311021"
] | null | [
"3'-phosphate/5'-hydroxy nucleic acid ligase activity"
] | [
"EXACT"
] | [] | [] | [
"EC:6.5.1.8",
"MetaCyc:RXN-17905",
"MetaCyc:RXN0-6566",
"RHEA:68076",
"RHEA:68080"
] | [
"GO:0008452"
] | [] | [] | [] | [
"GO:0008452"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch EC:6.5.1.8",
"skos:narrowMatch MetaCyc:RXN-17905",
"skos:narrowMatch MetaCyc:RXN0-6566",
"skos:narrowMatch RHEA:68076",
"skos:narrowMatch RHEA:68080",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27418\" xsd:anyURI"
] | ew | 2024-03-26T23:34:04Z | false | true | 7 |
GO:0170060 | 170,060 | microtubule destabilizing activity | molecular_function | A protein-containing complex destabilizing activity that promotes microtubule catastrophe (transition from microtubule growth to microtubule shrinkage). | [
"PMID:29858272",
"PMID:36435910"
] | null | [
"microtubule catastrophe inducing activity",
"microtubule catastrophe promoting activity"
] | [
"BROAD",
"BROAD"
] | [] | [] | [] | [
"GO:0140776"
] | [] | [] | [] | [
"GO:0140776"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25274\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29587\" xsd:anyURI"
] | ew | 2024-10-21T18:05:48Z | false | true | 9 |
GO:0170062 | 170,062 | nutrient storage | biological_process | The accumulation and maintenance in cells or tissues of a nutrient, a substance that is used by an organism to survive, to grow, and to reproduce; such as proteins, vitamins, and minerals. Nutrient reserves can be accumulated for mobilization and utilization when needed. | [
"GOC:ew"
] | null | [] | [] | [] | [] | [] | [
"GO:0009987"
] | [] | [] | [] | [
"GO:0009987"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17075\" xsd:anyURI"
] | ew | 2024-12-02T22:32:15Z | false | true | 2 |
GO:0170063 | 170,063 | transmembrane transport from lysosomal lumen to cytosol | biological_process | The directed movement of a solute from the lysosomal lumen across the lysosomal membrane and into the cytosol. | [
"PMID:26631267"
] | null | [
"export from lysosome lumen to cytosol"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0007041",
"GO:0010496",
"GO:0034486"
] | [] | [] | [] | [
"GO:0007041",
"GO:0010496",
"GO:0034486"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20070\" xsd:anyURI"
] | ew | 2024-12-09T20:53:08Z | false | true | 1 |
GO:0170064 | 170,064 | lysosome fission | biological_process | The process by which lysosomes undergo budding and fission to maintain their steady-state number, shape, size, composition and function, and to accomplish regeneration. | [
"PMID:31171420",
"PMID:38538795"
] | null | [] | [] | [] | [] | [] | [
"GO:0048285"
] | [] | [] | [] | [
"GO:0048285"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29628\" xsd:anyURI"
] | ew | 2025-01-31T20:15:44Z | false | true | 3 |
GO:0170066 | 170,066 | negative regulation of polyamine biosynthetic process | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups. | [
"PMID:9769097"
] | null | [] | [] | [] | [] | [] | [
"GO:0009890",
"GO:0010967",
"GO:0033239"
] | [
"negatively_regulates GO:0006596"
] | [
"negatively_regulates"
] | [
"GO:0006596"
] | [
"GO:0006596",
"GO:0009890",
"GO:0010967",
"GO:0033239"
] | [
"GO:0065007",
"negatively_regulates GO:0006596"
] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29814\" xsd:anyURI"
] | ew | 2025-03-11T19:55:32Z | false | true | 4 |
GO:0170067 | 170,067 | obsolete L-arginine biosynthetic process via N-acetyl-L-citrulline | biological_process | OBSOLETE. The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound N-acetyl-L-citrulline. | [
"PMID:16585758"
] | The reason for obsoletion is that this term represents a GO-CAM model. | [
"arginine biosynthesis via N-acetyl intermediates",
"arginine biosynthesis, N-acetylated pathway"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [] | [
"GO:0006526"
] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29602\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31525\" xsd:anyURI"
] | ew | 2025-03-14T17:04:09Z | true | true | 5 |
GO:0170069 | 170,069 | geranylgeranyltransferase-III complex | cellular_component | A protein-containing complex that catalyzes the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a mono-farnsylated substrate. In humans, the complex is comprised of a prenyltransferase alpha subunit, PTAR1 and beta subunit, RabGGTB, while in budding yeast the prenyltransferase complex contains ... | [
"PMID:32128853",
"PMID:33035318",
"PMID:35628237",
"PMID:40049413"
] | null | [
"geranylgeranyltransferase type 3 complex",
"geranylgeranyltransferase type-3 complex",
"GGT3",
"GGTase-3 complex",
"GGTase-III complex",
"GGTase3 complex",
"type-III geranylgeranyltransferase complex"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:1990234"
] | [
"part_of GO:0005829"
] | [
"part_of"
] | [
"GO:0005829"
] | [
"GO:0005829",
"GO:1990234"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29943\" xsd:anyURI"
] | ew | 2025-03-21T19:57:46Z | false | true | 2 |
GO:0170070 | 170,070 | negative regulation of mitochondrial transcription | biological_process | Any process that stops, prevents, or reduces the frequency, rate or extent of transcription occurring in the mitochondrion. | [
"PMID:23300484"
] | null | [] | [] | [] | [] | [] | [
"GO:0045892",
"GO:1903108"
] | [
"negatively_regulates GO:0006390"
] | [
"negatively_regulates"
] | [
"GO:0006390"
] | [
"GO:0006390",
"GO:0045892",
"GO:1903108"
] | [
"GO:0065007",
"negatively_regulates GO:0006390"
] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29938\" xsd:anyURI"
] | ew | 2025-06-09T17:43:39Z | false | true | 7 |
GO:0170071 | 170,071 | CROP complex | cellular_component | A complex involved in membrane fission during protein exchange in endo-lysosomal compartments. CROP joins members of two protein families: the peripheral subunits of retromer, a coat forming endosomal transport carriers, and membrane inserting PROPPINs. | [
"PMID:35466426"
] | null | [
"Cutting Retromer-On-PROPPIN"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0032991"
] | [] | [] | [] | [
"GO:0032991"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30686\" xsd:anyURI"
] | ew | 2025-08-12T21:56:57Z | false | true | 2 |
GO:0170074 | 170,074 | RADAR pathway | biological_process | A quality control pathway that degrades peroxisomal matrix protein receptors when the recycling machinery is blocked. When recycling to the cytosol fails, cargo-free receptors accumulate at the peroxisomal membrane, where they are polyubiquitinated and subsequently degraded by the ubiquitin-proteasome system (UPS). | [
"PMID:16390998",
"PMID:17011644",
"PMID:41076631"
] | null | [
"Receptor Accumulation and Degradation in the Absence of Recycling"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0043161"
] | [] | [] | [] | [
"GO:0043161"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31570\" xsd:anyURI"
] | ew | 2026-02-17T22:02:27Z | false | true | 9 |
GO:0170075 | 170,075 | negative regluation of nuclear-transribed mRNA catabolic process, no-go decay | biological_process | Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, no-go decay. | [
"PMID:41607283"
] | null | [
"negative regulation of no-go decay",
"negative regulation of no-go mRNA decay",
"negative regulation of nuclear-transcribed mRNA breakdown, no-go decay",
"negative regulation of nuclear-transcribed mRNA catabolism, no-go decay",
"negative regulation of nuclear-transcribed mRNA degradation, no-go decay"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:1902373"
] | [
"negatively_regulates GO:0070966"
] | [
"negatively_regulates"
] | [
"GO:0070966"
] | [
"GO:0070966",
"GO:1902373"
] | [
"GO:0065007",
"negatively_regulates GO:0070966"
] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31747\" xsd:anyURI"
] | ew | 2026-03-23T21:12:37Z | false | true | 2 |
GO:0180000 | 180,000 | histone methyltransferase inhibitor activity | molecular_function | Binds to and stops, prevents or reduces the activity of a histone methyltransferase. | [
"PMID:30923826"
] | null | [] | [] | [] | [] | [] | [
"GO:0004857"
] | [] | [] | [] | [
"GO:0004857"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24785\" xsd:anyURI"
] | vw | 2023-01-27T12:31:33Z | false | true | 1 |
GO:0180001 | 180,001 | cyclic-di-AMP binding | molecular_function | Binding to a cyclic di-AMP nucleotide. | [
"PMID:32843560",
"PMID:36629470"
] | null | [
"cyclic dimeric adenosine monophosphate binding"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0030551",
"GO:0032559"
] | [] | [] | [] | [
"GO:0030551",
"GO:0032559"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25203\" xsd:anyURI"
] | vw | 2023-03-31T08:52:09Z | false | true | 2 |
GO:0180002 | 180,002 | renal zinc excretion | biological_process | The elimination of zinc ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine. | [
"PMID:28196538"
] | null | [
"renal zinc ion excretion",
"renal zinc secretion"
] | [
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0097254"
] | [] | [] | [] | [
"GO:0097254"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24307\" xsd:anyURI"
] | vw | 2022-11-01T17:35:12Z | false | true | 5 |
GO:0180003 | 180,003 | S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity | molecular_function | Catalysis of the reaction: S-adenosyl-L-homocysteine(out) + S-adenosyl-L-methionine(in) = S-adenosyl-L-homocysteine(in) + S-adenosyl-L-methionine(out). | [
"PMID:14674884",
"PMID:34375635"
] | null | [] | [] | [] | [] | [
"RHEA:75479"
] | [
"GO:0000095",
"GO:0015179",
"GO:0015211",
"GO:0015297",
"GO:0072349"
] | [] | [] | [] | [
"GO:0000095",
"GO:0015179",
"GO:0015211",
"GO:0015297",
"GO:0072349"
] | [] | [] | [] | [] | [] | [
"skos:exactMatch RHEA:75479",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24887\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI"
] | vw | 2023-02-10T13:06:12Z | false | true | 1 |
GO:0180004 | 180,004 | RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity | molecular_function | Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-tyrosine (consensus YSPTSPS)(position 1) + H2O = RNA polymerase II large subunit + phosphate. | [
"PMID:22622228"
] | null | [
"RNA polymerase II C-terminal domain Y1 phosphatase activity"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch EC:3.1.3.16",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI"
] | vw | 2023-02-17T14:58:57Z | false | true | 8 |
GO:0180005 | 180,005 | RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity | molecular_function | Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-threonine (consensus YSPTSPS)(position 4) + H2O = RNA polymerase II large subunit + phosphate. | [
"PMID:22622228"
] | null | [
"RNA polymerase II C-terminal domain T4 phosphatase activity"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch EC:3.1.3.16",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI"
] | vw | 2023-02-17T15:02:16Z | false | true | 2 |
GO:0180006 | 180,006 | RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity | molecular_function | Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 2) + H2O = RNA polymerase II large subunit + phosphate. | [
"PMID:22622228"
] | null | [
"RNA polymerase II C-terminal domain S2 phosphatase activity"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch EC:3.1.3.16",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI"
] | vw | 2023-02-17T15:05:10Z | false | true | 9 |
GO:0180007 | 180,007 | RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity | molecular_function | Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 5) + H2O = RNA polymerase II large subunit + phosphate. | [
"PMID:22622228"
] | null | [
"RNA polymerase II C-terminal domain S5 phosphatase activity"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch EC:3.1.3.16",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI"
] | vw | 2023-02-17T15:09:01Z | false | true | 6 |
GO:0180008 | 180,008 | RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity | molecular_function | Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 7) + H2O = RNA polymerase II large subunit + phosphate. | [
"PMID:22622228"
] | null | [
"RNA polymerase II C-terminal domain S7 phosphatase activity"
] | [
"EXACT"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [
"GO:0008420"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch EC:3.1.3.16",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI"
] | vw | 2023-02-17T15:10:24Z | false | true | 2 |
GO:0180009 | 180,009 | broad specificity neutral L-amino acid:basic L-amino acid antiporter activity | molecular_function | Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: basic L-amino acid(in) + neutral L-amino acid(out) = basic L-amino acid(in) + neutral L-amino acid(out). | [
"PMID:23506863",
"PMID:8663357"
] | null | [
"neutral L-amino acid:cationic L-amino acid antiporter activity",
"neutral L-amino acid:dibasic L-amino acid antiporter activity",
"neutral L-amino acid:positively-charged polar L-amino acid antiporter activity",
"system b(0,+)-type activity"
] | [
"EXACT",
"EXACT",
"EXACT",
"RELATED"
] | [] | [] | [
"RHEA:71059",
"RHEA:71067",
"RHEA:71071",
"RHEA:71075"
] | [
"GO:0015174",
"GO:0015175",
"GO:0015297"
] | [] | [] | [] | [
"GO:0015174",
"GO:0015175",
"GO:0015297"
] | [] | [] | [] | [] | [] | [
"skos:narrowMatch RHEA:71059",
"skos:narrowMatch RHEA:71067",
"skos:narrowMatch RHEA:71071",
"skos:narrowMatch RHEA:71075",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24497\" xsd:anyURI"
] | vw | 2023-04-06T09:22:30Z | false | true | 7 |
GO:0180010 | 180,010 | co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway | biological_process | Any process involved in transcription termination-coupled 3' processing of RNA polymerase II mRNA transcripts by the 3' end cleavage and addition of a poly(A) tail. | [
"PMID:31499460"
] | null | [
"cotranscriptional 3' processing of RNA polymerase II mRNA transcripts",
"mRNA polyadenylation"
] | [
"EXACT",
"RELATED"
] | [] | [] | [
"Reactome:R-HSA-9770562 \"mRNA Polyadenylation\""
] | [
"GO:0031124",
"GO:0180012"
] | [] | [] | [] | [
"GO:0031124",
"GO:0180012"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24921\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27004\" xsd:anyURI"
] | vw | 2023-02-23T11:56:19Z | false | true | 7 |
GO:0180012 | 180,012 | co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway | biological_process | Any process involved in transcription termination-coupled 3' processing of RNA polymerase II RNA transcripts by 3' end cleavage and addition of a poly(A) tail. | [
"PMID:31499460"
] | null | [
"cotranscriptional 3'-end processing of RNA polymerase II transcripts"
] | [
"EXACT"
] | [] | [] | [
"PMID:31499460"
] | [
"GO:0031123"
] | [] | [] | [] | [
"GO:0031123"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24921\" xsd:anyURI"
] | vw | 2023-02-23T12:18:59Z | false | true | 9 |
GO:0180013 | 180,013 | lysophosphatidylserine flippase activity | molecular_function | Catalysis of the movement of a lysophosphatidylserine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP. | [
"PMID:34645814"
] | null | [] | [] | [] | [] | [] | [
"GO:0140333"
] | [] | [] | [] | [
"GO:0140333"
] | [] | [] | [] | [] | [] | [
"skos:broadMatch RHEA:66132"
] | vw | 2023-02-23T14:32:13Z | false | true | 2 |
GO:0180014 | 180,014 | protein-tRNA adaptor activity | molecular_function | The binding activity of a protein that brings together another protein and a tRNA, permitting those molecules to function in a coordinated way. | [
"PMID:31048492"
] | null | [
"tRNA carrier"
] | [
"RELATED"
] | [] | [] | [] | [
"GO:0140517"
] | [] | [] | [] | [
"GO:0140517"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25046\" xsd:anyURI"
] | vw | 2023-03-02T11:03:26Z | false | true | 1 |
GO:0180015 | 180,015 | nucleoside import across plasma membrane | biological_process | The directed movement of nucleoside from outside of a cell, across the plasma membrane and into the cytosol. | [
"PMID:21998139",
"PMID:30658162"
] | null | [] | [] | [] | [] | [] | [
"GO:0098739",
"GO:1901642"
] | [] | [] | [] | [
"GO:0098739",
"GO:1901642"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25031\" xsd:anyURI"
] | vw | 2023-03-02T16:44:33Z | false | true | 2 |
GO:0180016 | 180,016 | SUMO ligase regulator activity | molecular_function | Binds to and modulates the activity of a SUMO ligase. | [
"PMID:19363481",
"PMID:33446573"
] | null | [] | [] | [] | [] | [] | [
"GO:0055103"
] | [] | [] | [] | [
"GO:0055103"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25052\" xsd:anyURI"
] | vw | 2023-03-03T15:33:58Z | false | true | 9 |
GO:0180018 | 180,018 | cytoplasmic polyadenylation-dependent RNA catabolic process | biological_process | The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate. | [
"PMID:20368444"
] | null | [] | [] | [] | [] | [] | [
"GO:0043633"
] | [] | [] | [] | [
"GO:0043633"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25009\" xsd:anyURI"
] | vw | 2023-05-15T11:18:39Z | false | true | 7 |
GO:0180019 | 180,019 | Knl1/Spc105 complex | cellular_component | A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It is involved in kinetochore-microtubule binding, recruiting microtubule binding outer kinetochore subunits. It is essential for kinetochore binding by components of the spindle assembly checkpoint. In humans, budding... | [
"PMID:14565975",
"PMID:19893618"
] | null | [
"KNL-1 complex",
"KNL1 complex",
"Spc105 complex",
"Spc105p/Kre28p complex"
] | [
"EXACT",
"EXACT",
"EXACT",
"EXACT"
] | [] | [] | [] | [
"GO:0032991"
] | [
"part_of GO:0000940"
] | [
"part_of"
] | [
"GO:0000940"
] | [
"GO:0000940",
"GO:0032991"
] | [] | [] | [] | [] | [] | [
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25544\" xsd:anyURI",
"term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31052\" xsd:anyURI"
] | vw | 2023-06-16T09:53:26Z | false | true | 2 |
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