go_id
string
go_numeric_id
int64
name
string
namespace
string
definition
string
definition_xrefs
list
comment
string
synonyms
list
synonym_scopes
list
alt_ids
list
subsets
list
xrefs
list
is_a_ids
list
relationship_edges
list
relationship_types
list
relationship_target_ids
list
parent_ids
list
intersection_of
list
union_of
list
disjoint_from
list
replaced_by
list
consider
list
property_values
list
created_by
string
creation_date
string
is_obsolete
bool
in_go_basic
bool
split_bucket
int64
GO:0160286
160,286
queuosine transmembrane transporter activity
molecular_function
Enables the transfer of queuosine from one side of a membrane to the other according to the reaction: queuosine(out) = queuosine(in).
[ "PMID:40526720", "RHEA:85683" ]
null
[]
[]
[]
[]
[ "RHEA:85683" ]
[ "GO:0005337" ]
[ "part_of GO:0160287" ]
[ "part_of" ]
[ "GO:0160287" ]
[ "GO:0005337", "GO:0160287" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:85683", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30470\" xsd:anyURI" ]
rynl
2025-06-27T00:30:53Z
false
true
4
GO:0160287
160,287
queuosine import across plasma membrane
biological_process
The directed movement of queuosine from outside of a cell, across the plasma membrane and into the cytosol.
[ "PMID:40526720" ]
null
[]
[]
[]
[]
[]
[ "GO:0098739", "GO:1901642" ]
[]
[]
[]
[ "GO:0098739", "GO:1901642" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30470\" xsd:anyURI" ]
rynl
2025-06-27T00:35:07Z
false
true
1
GO:0160288
160,288
cytoplasmic side of trans-Golgi cisterna membrane
cellular_component
The leaflet of the trans-Golgi cisternae membrane that faces the cytoplasm, including any protein embedded in, attached to, or peripherally associated with it. This is the site where vesicle formation, and cargo sorting towards post-Golgi destinations such as endosomes, lysosomes and the plasma membrane occur.
[ "PMID:23913272", "PMID:34597626", "PMID:37566051" ]
null
[ "cytoplasmic face of Golgi trans cisterna membrane", "cytoplasmic leaflet of Golgi trans cisterna membrane", "cytoplasmic side of Golgi trans cisternae membrane" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0098562" ]
[ "part_of GO:1990676" ]
[ "part_of" ]
[ "GO:1990676" ]
[ "GO:0098562", "GO:1990676" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30509\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31515\" xsd:anyURI" ]
rynl
2025-06-27T05:51:59Z
false
true
8
GO:0160289
160,289
lumenal side of trans-Golgi cisternae membrane
cellular_component
The leaflet of the trans-Golgi cisternae membrane that faces the Golgi lumen, including any protein embedded in, attached to, or peripherally associated with it. This is the site where the final steps of glycan processing, proteolytic modification, and cargo maturation prior to sorting at the trans-Golgi network occur.
[ "PMID:34597626", "PMID:38307322", "PMID:6121819" ]
null
[ "lumenal face of trans-Golgi cisternae membrane", "lumenal leaflet of trans-Golgi cisternae membrane", "lumenal side of Golgi trans cisternae membrane" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0098576" ]
[ "part_of GO:1990676" ]
[ "part_of" ]
[ "GO:1990676" ]
[ "GO:0098576", "GO:1990676" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30510\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31515\" xsd:anyURI" ]
rynl
2025-06-27T06:11:48Z
false
true
1
GO:0160290
160,290
2-oxoglutarate-dependent tRNA 5-methylcytidine formyltransferase activity
molecular_function
Catalysis of the reaction: 5-methylcytidine(34) in mitochondrial tRNA(Met) + 2 2-oxoglutarate + 2 O2 = 5-formylcytidine(34) in mitochondrial tRNA(Met) + 2 succinate + 2 CO2 + H2O.
[ "PMID:27497299", "PMID:28472312", "RHEA:54144" ]
null
[]
[]
[]
[]
[ "RHEA:54144" ]
[ "GO:0016706", "GO:0140101" ]
[]
[]
[]
[ "GO:0016706", "GO:0140101" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:54144" ]
rynl
2025-07-05T00:30:16Z
false
true
4
GO:0160291
160,291
phosphatidylinositol-4-phosphate-cholesterol exchange activity
molecular_function
Catalysis of the reaction: a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(out) + cholesterol(in) = 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-phosphate)(in) + cholesterol(out). This reaction results in the exchange of cholesterol for phosphatidylinositol-4-phosphate (PI(4)P) between membranes.
[ "PMID:24209621", "PMID:29596003", "RHEA:84179" ]
null
[]
[]
[]
[]
[ "RHEA:84179" ]
[ "GO:0120014", "GO:0120020", "GO:7770011" ]
[]
[]
[]
[ "GO:0120014", "GO:0120020", "GO:7770011" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:84179", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27059\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30432\" xsd:anyURI" ]
rynl
2025-07-16T17:44:49Z
false
true
5
GO:0160292
160,292
sodium-translocating NADH:quinone reductase complex
cellular_component
A bacterial protein complex consisting of six subunits, NqrABCDEF, encoded by the nqr operon, which catalyzes electron transfer from NADH to ubiquinone in the respiratory chain coupled with the transport of sodium ions from the cytoplasm to the periplasm.
[ "PMID:38955304" ]
null
[ "Na(+)-translocating NADH-quinone reductase complex", "Na+-NQR complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30612\" xsd:anyURI" ]
rynl
2025-07-25T22:59:20Z
false
true
3
GO:0160294
160,294
clathrin- and caveolae-independent endocytosis
biological_process
An endocytosis process that internalizes cargo via small, non-coated vesicles (~40-80 nm) without relying on clathrin or caveolin and can be dynamin-dependent or dynamin-independent.
[ "PMID:15668298", "PMID:31976201" ]
null
[]
[]
[]
[]
[]
[ "GO:0006897" ]
[]
[]
[]
[ "GO:0006897" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30667\" xsd:anyURI" ]
rynl
2025-08-04T16:38:59Z
false
true
8
GO:0160295
160,295
mitochondrial complex I intermediate assembly complex
cellular_component
A protein complex involved in mitochondrial respiratory chain complex I (MCI) assembly. The mitochondrial complex I intermediate assembly (MCIA) complex is an inner mitochondrial membrane complex required for the aggregation, arrangement and bonding together of the subunits of the ND2-module of MCI. In humans, the MCIA...
[ "PMID:32320651" ]
null
[ "MCIA complex", "mitochondrial CI assembly complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0098800" ]
[]
[]
[]
[ "GO:0098800" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30671\" xsd:anyURI" ]
rynl
2025-08-05T23:37:22Z
false
true
8
GO:0160297
160,297
IRES-mediated translation initiation factor activity
molecular_function
A translation initiation factor activity that enables interaction with internal ribosome entry sites (IRESs) located within mRNA, promoting ribosome recruitment and assembly at internal initiation sites and translation initiation independent of the 5' cap structure.
[ "PMID:21118130", "PMID:31913484" ]
null
[]
[]
[]
[]
[]
[ "GO:0003743" ]
[]
[]
[]
[ "GO:0003743" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30674\" xsd:anyURI" ]
rynl
2025-08-11T18:54:21Z
false
true
6
GO:0160298
160,298
pyridinol guanylyltransferase activity
molecular_function
Catalysis of the reaction: 6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol + GTP + H+ = guanylylpyridinol + diphosphate.
[ "PMID:24249552", "RHEA:85479" ]
null
[]
[]
[]
[]
[ "EC:2.7.7.109", "KEGG_REACTION:R13518", "RHEA:85479" ]
[ "GO:0070568" ]
[]
[]
[]
[ "GO:0070568" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.7.7.109", "skos:exactMatch RHEA:85479", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30718\" xsd:anyURI" ]
rynl
2025-08-21T00:46:39Z
false
true
8
GO:0160301
160,301
guanylylpyridinol adenylase activity
molecular_function
Catalysis of the reaction: guanylylpyridinol + ATP + H+ = guanylylpyridinol-AMP + diphosphate.
[ "PMID:25882909", "RHEA:85487" ]
null
[]
[]
[]
[]
[ "EC:2.7.7.110", "KEGG_REACTION:R13520", "RHEA:85487" ]
[ "GO:0016779" ]
[]
[]
[]
[ "GO:0016779" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:2.7.7.110", "skos:exactMatch RHEA:85487", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30720\" xsd:anyURI" ]
rynl
2025-08-21T22:49:37Z
false
true
7
GO:0160302
160,302
6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol 3-C-methyltransferase activity
molecular_function
Catalysis of the reaction: 6-carboxymethyl-5-methyl-4-hydroxypyridin-2-ol + S-adenosyl-L-methionine = 6-carboxymethyl-3,5-dimethyl-4-hydroxypyridin-2-ol + S-adenosyl-L-homocysteine + H+.
[ "PMID:27391308", "RHEA:85483" ]
null
[]
[]
[]
[]
[ "KEGG_REACTION:R13499", "RHEA:85483" ]
[ "GO:0008168" ]
[]
[]
[]
[ "GO:0008168" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:85483", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30721\" xsd:anyURI" ]
rynl
2025-08-21T23:15:13Z
false
true
5
GO:0160303
160,303
protein secretion by the type IX secretion system
biological_process
The process by which proteins are transported from the periplasmic space across the outer membrane of Bacteroidota bacteria via the type IX secretion system (T9SS).
[ "PMID:19966289", "PMID:37043368", "PMID:40490843" ]
null
[ "Por secretion system", "PorSS", "T9SS" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009306", "GO:0071806" ]
[]
[]
[]
[ "GO:0009306", "GO:0071806" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30722\" xsd:anyURI" ]
rynl
2025-08-22T00:30:40Z
false
true
3
GO:0160304
160,304
4-vinylphenol methyltransferase activity
molecular_function
Catalysis of the reaction: 4-vinylphenol + S-adenosyl-L-methionine = 4-vinylanisole + S-adenosyl-L-homocysteine + H+.
[ "PMID:40562929", "RHEA:86075" ]
null
[]
[]
[]
[]
[ "RHEA:86075" ]
[ "GO:0008171", "GO:0008757" ]
[]
[]
[]
[ "GO:0008171", "GO:0008757" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:86075", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30708\" xsd:anyURI" ]
rynl
2025-08-23T00:16:21Z
false
true
4
GO:0160305
160,305
4-vinylanisole biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of 4-vinylanisole. 4-vinylanisole derived from food plant phenylalanin is the aggregation pheromone specifically released by gregarious migratory locusts.
[ "PMID:40562929" ]
null
[]
[]
[]
[]
[]
[ "GO:0042537", "GO:0042811", "GO:1901503" ]
[]
[]
[]
[ "GO:0042537", "GO:0042811", "GO:1901503" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30708\" xsd:anyURI" ]
rynl
2025-08-23T00:32:14Z
false
true
3
GO:0160306
160,306
swarm social behavior
biological_process
A social behavior in which multiple individuals of the same animal species coordinate their movement in close spatial proximity, forming a dynamic aggregation typically characterized by collective motion, cohesion, and mutual responsiveness among members of the group.
[ "DOI:10.1007/s13592-013-0253-2", "PMID:23740485", "PMID:32788724" ]
null
[ "swarming behavior" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0035176" ]
[]
[]
[]
[ "GO:0035176" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30708\" xsd:anyURI" ]
rynl
2025-08-27T22:14:18Z
false
true
5
GO:0160307
160,307
protein biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of protein.
[ "Wikipedia:Protein_biosynthesis" ]
null
[ "protein biosynthesis", "protein synthesis" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0009059", "GO:0019538" ]
[ "has_part GO:0043039", "part_of GO:0010467" ]
[ "has_part", "part_of" ]
[ "GO:0043039", "GO:0010467" ]
[ "GO:0009059", "GO:0010467", "GO:0019538", "GO:0043039" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15375\" xsd:anyURI" ]
rynl
2025-09-29T23:16:32Z
false
true
6
GO:0160308
160,308
succinate dehydrogenase (FAD) activity
molecular_function
Catalysis of the reaction: FAD + succinate + H+ = fumarate + FADH2.
[ "RHEA:30343", "WIKIPEDIA:SDHA" ]
null
[]
[]
[]
[]
[ "RHEA:30343" ]
[ "GO:0000104" ]
[]
[]
[]
[ "GO:0000104" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:30343", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30805\" xsd:anyURI" ]
rynl
2025-10-20T18:32:39Z
false
true
9
GO:0160309
160,309
commander complex
cellular_component
A protein complex that promotes the recycling of internalized transmembrane proteins from endosomes back to the plasma membrane. The commander complex consists of the CCC (COMMD/CCDC22/CCDC93) subcomplex and the retriever subcomplex. In human, the CCC subcomplex consists of COMMD1, COMMD2, COMMD3, COMMD4, COMMD5, COMMD...
[ "PMID:28892079", "PMID:37172566" ]
null
[]
[]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31090\" xsd:anyURI" ]
rynl
2025-11-19T23:57:27Z
false
true
8
GO:0160310
160,310
dopamine loading into synaptic vesicle
biological_process
The active transport of dopamine neurotransmitters into a synaptic vesicle.
[ "PMID:29666153" ]
null
[]
[]
[]
[]
[]
[ "GO:0015872", "GO:0098700" ]
[]
[]
[]
[ "GO:0015872", "GO:0098700" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31143\" xsd:anyURI" ]
rynl
2025-12-02T22:02:35Z
false
true
3
GO:0160311
160,311
tyramine loading into synaptic vesicle
biological_process
The active transport of tyramine neurotransmitters into a synaptic vesicle.
[ "PMID:15849736", "PMID:9870940" ]
null
[]
[]
[]
[]
[]
[ "GO:0098700", "GO:7770032" ]
[]
[]
[]
[ "GO:0098700", "GO:7770032" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31143\" xsd:anyURI" ]
rynl
2025-12-02T23:16:14Z
false
true
1
GO:0160313
160,313
endosomal intralumenal vesicle
cellular_component
A membrane-bounded vesicle that is located within the lumen of an endosome.
[ "PMID:21878991", "PMID:31854087" ]
null
[ "ILV" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0031410" ]
[ "part_of GO:0005768" ]
[ "part_of" ]
[ "GO:0005768" ]
[ "GO:0005768", "GO:0031410" ]
[ "GO:0097708", "part_of GO:0005768" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31158\" xsd:anyURI" ]
rynl
2025-12-04T17:58:06Z
false
true
6
GO:0160314
160,314
endosomal intralumenal vesicle membrane
cellular_component
The lipid bilayer surrounding an intraluminal vesicle within an endososome.
[ "PMID:31854087", "PMID:38706230" ]
null
[ "endosome ILV membrane", "endosome internal vesicle membrane" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0030659", "GO:0098588" ]
[ "part_of GO:0160313" ]
[ "part_of" ]
[ "GO:0160313" ]
[ "GO:0030659", "GO:0098588", "GO:0160313" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31159\" xsd:anyURI" ]
rynl
2025-12-08T16:52:03Z
false
true
1
GO:0160315
160,315
endosomal intralumenal vesicle lumen
cellular_component
The volume enclosed by the membrane of an intraluminal vesicle within an endosome.
[ "PMID:31854087", "PMID:38706230" ]
null
[ "endosome ILV lumen", "endosome internal vesicle lumen" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0070013" ]
[ "part_of GO:0160313" ]
[ "part_of" ]
[ "GO:0160313" ]
[ "GO:0070013", "GO:0160313" ]
[ "GO:0031974", "part_of GO:0160313" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31159\" xsd:anyURI" ]
rynl
2025-12-08T17:33:35Z
false
true
9
GO:0160316
160,316
endolysosomal intralumenal vesicle
cellular_component
A membrane-bounded vesicle that is located within the lumen of an endolysosome.
[ "PMID:31854087", "PMID:38706230" ]
null
[ "endolysosomal ILV" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0160313" ]
[ "part_of GO:0036019" ]
[ "part_of" ]
[ "GO:0036019" ]
[ "GO:0036019", "GO:0160313" ]
[ "GO:0097708", "part_of GO:0036019" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31158\" xsd:anyURI" ]
rynl
2025-12-24T00:02:56Z
false
true
5
GO:0160317
160,317
endolysosomal intralumenal vesicle membrane
cellular_component
The lipid bilayer surrounding an intraluminal vesicle within an endolysosome.
[ "PMID:31854087", "PMID:38706230" ]
null
[ "endolysosome ILV membrane", "endolysosome internal vesicle membrane" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0160314" ]
[ "part_of GO:0160316" ]
[ "part_of" ]
[ "GO:0160316" ]
[ "GO:0160314", "GO:0160316" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31159\" xsd:anyURI" ]
rynl
2025-12-24T00:06:07Z
false
true
4
GO:0160318
160,318
endolysosomal intralumenal vesicle lumen
cellular_component
The volume enclosed by the membrane of an intraluminal vesicle within an endolysosome.
[ "PMID:31854087", "PMID:38706230" ]
null
[ "endolysosome ILV lumen", "endolysosome internal vesicle lumen" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0005775", "GO:0160315" ]
[ "part_of GO:0160316" ]
[ "part_of" ]
[ "GO:0160316" ]
[ "GO:0005775", "GO:0160315", "GO:0160316" ]
[ "GO:0031974", "part_of GO:0160316" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31160\" xsd:anyURI" ]
rynl
2025-12-24T00:18:06Z
false
true
3
GO:0160319
160,319
lipoyl-dependent peroxiredoxin activity
molecular_function
Catalysis of the reaction: N(6)-[(R)-dihydrolipoyl]-L-lysyl-[lipoyl-carrier protein] + a hydroperoxide = N(6)-[(R)-lipoyl]-L-lysyl-[lipoyl-carrier protein] + an alcohol + H2O.
[ "EC:1.11.1.28", "RHEA:62636" ]
null
[]
[]
[]
[]
[ "EC:1.11.1.28", "RHEA:62636" ]
[ "GO:0004601" ]
[]
[]
[]
[ "GO:0004601" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.11.1.28", "skos:exactMatch RHEA:62636", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31239\" xsd:anyURI" ]
rynl
2025-12-29T00:52:44Z
false
true
9
GO:0160320
160,320
obsolete protein-tyrosine iodotransferase activity
molecular_function
OBSOLETE. Catalysis of the reaction: [thyroglobulin]-L-tyrosine + iodide + H2O2 + H+ = [thyroglobulin]-3-iodo-L-tyrosine + 2 H2O and [thyroglobulin]-3-iodo-L-tyrosine + iodide + H2O2 + H+ = [thyroglobulin]-3,5-diiodo-L-tyrosine + 2 H2O.
[ "PMID:36537574", "PMID:8651700" ]
The reason for obsoletion is that the reactions covered by this term (RHEA:48956 and RHEA:48960) are now subsumed by the updated GO:0004447 (iodide peroxidase activity), which covers all 5 thyroid peroxidase reactions.
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0004447" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30596\" xsd:anyURI" ]
null
null
true
true
7
GO:0170002
170,002
halotropism
biological_process
A sodium-specific negative tropism that is crucial for surviving and thriving under high salinity.
[ "PMID:36243013" ]
null
[ "root halotropism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0009606" ]
[]
[]
[]
[ "GO:0009606" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24300\" xsd:anyURI" ]
ew
2022-11-01T17:36:17Z
false
true
3
GO:0170004
170,004
lipoate transmembrane transporter activity
molecular_function
Enables the transfer of lipoate from one side of a membrane to the other.
[ "PMID:20980265", "PMID:25971966" ]
null
[]
[]
[]
[]
[]
[ "GO:0022857" ]
[]
[]
[]
[ "GO:0022857" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25332\" xsd:anyURI" ]
ew
2023-06-06T17:38:04Z
false
true
2
GO:0170005
170,005
cyclic nucleotide phosphodiesterase activator activity
molecular_function
Binds to and increases the activity of cyclic nucleotide phosphodiesterase.
[ "PMID:6087882", "PMID:6259174", "PMID:6667031" ]
null
[]
[]
[]
[]
[]
[ "GO:0008047" ]
[ "positively_regulates GO:0004112" ]
[ "positively_regulates" ]
[ "GO:0004112" ]
[ "GO:0004112", "GO:0008047" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24706\" xsd:anyURI" ]
ew
2023-01-24T19:49:38Z
false
true
2
GO:0170006
170,006
lipoate transmembrane transport
biological_process
The process in which lipoate is transported across a membrane.
[ "PMID:20980265", "PMID:25971966" ]
null
[]
[]
[]
[]
[]
[ "GO:0055085" ]
[]
[]
[]
[ "GO:0055085" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25332\" xsd:anyURI" ]
ew
2023-06-06T17:40:56Z
false
true
3
GO:0170007
170,007
endoplasmic reticulum-lipid droplet tether activity
molecular_function
The binding activity of a molecule that brings together a lipid droplet with an endoplasmic reticulum membrane, via membrane lipid binding, to establish membrane contact sites and mediate exchange and communication.
[ "PMID:35389430" ]
null
[]
[]
[]
[]
[ "Reactome:R-HSA-8857686 \"FITM2 binds TAGs\"", "Reactome:R-HSA-9942190 \"FITM1 binds TAGs\"" ]
[ "GO:0043495" ]
[]
[]
[]
[ "GO:0043495" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25428\" xsd:anyURI" ]
ew
2023-06-06T18:21:51Z
false
true
2
GO:0170008
170,008
mRNA phosphatase activator activity
molecular_function
Binds to and increases the activity of mRNA phosphatase.
[ "PMID:22323607" ]
null
[]
[]
[]
[]
[]
[ "GO:0008047" ]
[ "positively_regulates GO:0140818" ]
[ "positively_regulates" ]
[ "GO:0140818" ]
[ "GO:0008047", "GO:0140818" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24720\" xsd:anyURI" ]
ew
2023-01-25T18:31:14Z
false
true
9
GO:0170009
170,009
endoplasmic reticulum-organelle membrane tether activity
molecular_function
The binding activity of a molecule that brings together two membranes, either via membrane lipid binding or by interacting with a membrane protein, to establish or maintain membrane contact sites and mediate organelle exchange and communication.
[ "PMID:29858488" ]
null
[]
[]
[]
[]
[]
[ "GO:0043495" ]
[]
[]
[]
[ "GO:0043495" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25429\" xsd:anyURI" ]
ew
2023-06-29T16:28:28Z
false
true
9
GO:0170010
170,010
nonsense-mediated decay complex
cellular_component
A highly conserved protein complex that recognises and elicits the rapid degradation of mRNAs in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
[ "GOC:lnp", "PMID:1569946", "PMID:29282598", "PMID:9032286" ]
null
[ "Upf complex" ]
[ "EXACT" ]
[]
[]
[ "IntAct:EBI-16420380" ]
[ "GO:1902494" ]
[]
[]
[]
[ "GO:1902494" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/15365\" xsd:anyURI" ]
ew
2023-02-02T16:55:18Z
false
true
9
GO:0170011
170,011
stalled ribosome sensor activity
molecular_function
A molecule that recognizes stalled ribosomes and initiates a signaling response.
[ "PMID:32289254", "PMID:32610081", "PMID:36638793" ]
null
[]
[]
[]
[]
[]
[ "GO:0140299" ]
[ "has_part GO:0043022" ]
[ "has_part" ]
[ "GO:0043022" ]
[ "GO:0043022", "GO:0140299" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24865\" xsd:anyURI" ]
ew
2023-02-09T20:20:22Z
false
true
1
GO:0170012
170,012
histone H3K18 decrotonylase activity
molecular_function
Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone H3 position 18] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone H3] + nicotinamide.
[ "PMID:34927582" ]
Comment: Note that the residue position corresponds to the canonical human H3 histone (UniProtKB:P84243); this residue is conserved across all eukaryotes. Residue 1 is the first residue following removal of the initiating Methionine (Met). Note that each histone is encoded by multiple genes, and sequences may vary acro...
[]
[]
[]
[]
[]
[ "GO:0160012" ]
[]
[]
[]
[ "GO:0160012" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:69332", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24466\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
ew
2023-02-09T20:55:09Z
false
true
1
GO:0170013
170,013
channel complex
cellular_component
A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
[ "PMID:10839820" ]
null
[]
[]
[]
[]
[]
[ "GO:0098796" ]
[]
[]
[]
[ "GO:0098796" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20026\" xsd:anyURI" ]
ew
2023-03-01T01:48:30Z
false
true
1
GO:0170014
170,014
ankyrin-1 complex
cellular_component
A complex composed of ANK1, RHCE, RHAG, SLC4A1, EPB42, GYPA, GYPB and AQP1, that functions in the stability and shape of the erythrocyte membrane in human.
[ "PMID:35835865" ]
null
[ "ankyrin complex", "erythrocyte ankyrin-1 complex" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0098796" ]
[]
[]
[]
[ "GO:0098796" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24929\" xsd:anyURI" ]
ew
2023-03-01T18:24:19Z
false
true
5
GO:0170015
170,015
carbon dioxide receptor activity
molecular_function
Combining with carbon dioxide to initiate a change in cell activity.
[ "PMID:24240097" ]
null
[]
[]
[]
[]
[]
[ "GO:0038023" ]
[]
[]
[]
[ "GO:0038023" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24994\" xsd:anyURI" ]
ew
2023-03-08T01:05:36Z
false
true
1
GO:0170016
170,016
endoplasmic reticulum-endosome tether activity
molecular_function
The binding activity of a molecule that brings together an endosome and an ER membrane either via membrane lipid binding or by interacting with an endosome protein, to establish and facilitate organelle exchange.
[ "PMID:33124732" ]
null
[]
[]
[]
[]
[]
[ "GO:0170009" ]
[]
[]
[]
[ "GO:0170009" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25429\" xsd:anyURI" ]
ew
2023-06-29T16:31:41Z
false
true
5
GO:0170020
170,020
ionotropic olfactory receptor activity
molecular_function
Enables the transmembrane transfer of an ion by a channel that opens when a specific odorant has been bound by the channel complex or one of its constituent parts.
[ "PMID:21857978", "PMID:24661599" ]
null
[]
[]
[]
[]
[]
[ "GO:0004984", "GO:0015276" ]
[]
[]
[]
[ "GO:0004984", "GO:0015276" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25525\" xsd:anyURI" ]
ew
2023-06-30T17:49:23Z
false
true
9
GO:0170021
170,021
ionotropic taste receptor activity
molecular_function
Enables the transmembrane transfer of an ion by a channel that opens when a soluble compound has been bound by the channel complex or one of its constituent parts.
[ "PMID:36828965" ]
null
[]
[]
[]
[]
[]
[ "GO:0008527", "GO:0015276" ]
[]
[]
[]
[ "GO:0008527", "GO:0015276" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25533\" xsd:anyURI" ]
ew
2023-07-03T19:05:36Z
false
true
2
GO:0170022
170,022
ionotropic bitter taste receptor activity
molecular_function
Enables the transmembrane transfer of an ion by a channel that opens when a specific bitter compound has been bound by the channel complex or one of its constituent parts.
[ "PMID:21262465" ]
null
[]
[]
[]
[]
[]
[ "GO:0170021" ]
[]
[]
[]
[ "GO:0170021" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25533\" xsd:anyURI" ]
ew
2023-07-03T19:22:08Z
false
true
8
GO:0170023
170,023
ionotropic sweet taste receptor activity
molecular_function
Enables the transmembrane transfer of an ion by a channel that opens when a specific soluble sweet compound has been bound by the channel complex or one of its constituent parts.
[ "PMID:24474785" ]
null
[]
[]
[]
[]
[]
[ "GO:0170021" ]
[]
[]
[]
[ "GO:0170021" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25533\" xsd:anyURI" ]
ew
2023-07-03T19:24:28Z
false
true
6
GO:0170027
170,027
SKA complex
cellular_component
An outer kinetochore complex involved in the attachment of microtubule ends to the chromosomes during mitosis. In humans, it contains the subunits SKA1, SKA2 and SKA3.
[ "PMID:19289083", "PMID:22483620" ]
null
[ "SKA1 complex" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[ "part_of GO:0000940" ]
[ "part_of" ]
[ "GO:0000940" ]
[ "GO:0000940", "GO:0032991" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25850\" xsd:anyURI" ]
ew
2023-08-03T18:42:06Z
false
true
9
GO:0170033
170,033
L-amino acid metabolic process
biological_process
The chemical reactions and pathways involving an L-amino acid.
[ "GOC:edw" ]
null
[ "L-alpha-amino acid metabolism", "L-amino acid metabolism" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "Reactome:R-HSA-8963693 \"Aspartate and asparagine metabolism\"", "Reactome:R-HSA-8964539 \"Glutamate and glutamine metabolism\"" ]
[ "GO:1901605" ]
[]
[]
[]
[ "GO:1901605" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI" ]
ew
2023-11-20T23:41:23Z
false
true
6
GO:0170034
170,034
L-amino acid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of L-amino acids, the L-enantiomers of amino acids.
[ "GOC:edw" ]
null
[ "L-amino acid anabolism", "L-amino acid biosynthesis", "L-amino acid formation", "L-amino acid synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0170033", "GO:1901607" ]
[]
[]
[]
[ "GO:0170033", "GO:1901607" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI" ]
ew
2023-11-20T23:42:06Z
false
true
7
GO:0170035
170,035
L-amino acid catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of an L-amino acid.
[ "GOC:edw" ]
null
[ "L-amino acid breakdown", "L-amino acid catabolism", "L-amino acid degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0170033", "GO:1901606" ]
[]
[]
[]
[ "GO:0170033", "GO:1901606" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI" ]
ew
2023-11-21T00:55:07Z
false
true
6
GO:0170036
170,036
import into the mitochondrion
biological_process
The directed movement of substances from the cytosol into the mitochondrion.
[ "GOC:ew" ]
null
[]
[]
[]
[]
[]
[ "GO:0010496", "GO:1990542" ]
[]
[]
[]
[ "GO:0010496", "GO:1990542" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26201\" xsd:anyURI" ]
ew
2023-11-30T20:56:49Z
false
true
5
GO:0170038
170,038
proteinogenic amino acid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein.
[ "GOC:ew" ]
null
[ "proteinogenic amino acid anabolism", "proteinogenic amino acid biosynthesis", "proteinogenic amino acid formation", "proteinogenic amino acid synthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046394", "GO:0170039" ]
[]
[]
[]
[ "GO:0046394", "GO:0170039" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI" ]
ew
2023-12-18T16:28:19Z
false
true
5
GO:0170039
170,039
proteinogenic amino acid metabolic process
biological_process
The chemical reactions and pathways involving any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein.
[ "GOC:ew" ]
null
[ "proteinogenic amino acid metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006520", "GO:0019752" ]
[]
[]
[]
[ "GO:0006520", "GO:0019752" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI" ]
ew
2023-12-18T17:31:08Z
false
true
3
GO:0170040
170,040
proteinogenic amino acid catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of any amino acid that is incorporated into protein naturally by ribosomal translation of mRNA, and that has a specific codon for translation from mRNA to protein.
[ "GOC:ew" ]
null
[ "proteinogenic amino acid breakdown", "proteinogenic amino acid catabolism", "proteinogenic amino acid degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046395", "GO:0170039" ]
[]
[]
[]
[ "GO:0046395", "GO:0170039" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23268\" xsd:anyURI" ]
ew
2023-12-18T17:41:14Z
false
true
8
GO:0170041
170,041
non-proteinogenic amino acid metabolic process
biological_process
The chemical reactions and pathways involving non-proteingenic amino acids.
[ "GOC:ew" ]
null
[ "non-proteinogenic amino acid metabolism" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0006520", "GO:0019752" ]
[]
[]
[]
[ "GO:0006520", "GO:0019752" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23269\" xsd:anyURI" ]
ew
2023-12-18T17:57:55Z
false
true
3
GO:0170043
170,043
non-proteinogenic amino acid biosynthetic process
biological_process
The chemical reactions and pathways resulting in the formation of non-proteinogenic amino acids.
[ "GOC:ew" ]
null
[ "non-proteinogenic amino acid anabolism", "non-proteinogenic amino acid formation", "non-proteinogenic amino acid synthesis", "non-proteinogenic biosynthesis" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046394", "GO:0170041" ]
[]
[]
[]
[ "GO:0046394", "GO:0170041" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23269\" xsd:anyURI" ]
ew
2023-12-18T19:03:08Z
false
true
5
GO:0170044
170,044
non-proteinogenic amino acid catabolic process
biological_process
The chemical reactions and pathways resulting in the breakdown of non-proteinogenic amino acids.
[ "GOC:ew" ]
null
[ "non-proteinogenic amino acid breakdown", "non-proteinogenic amino acid catabolism", "non-proteinogenic amino acid degradation" ]
[ "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0046395", "GO:0170041" ]
[]
[]
[]
[ "GO:0046395", "GO:0170041" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/23269\" xsd:anyURI" ]
ew
2023-12-18T19:27:05Z
false
true
8
GO:0170046
170,046
isopentenyl pyrophosphate import into mitochondrion
biological_process
The process in which isopentenyl pyrophosphate is transported across a membrane into the mitochondrion.
[ "GOC:ew", "PMID:37813972" ]
null
[]
[]
[]
[]
[]
[ "GO:0015711", "GO:0015914", "GO:0032365", "GO:0170036" ]
[]
[]
[]
[ "GO:0015711", "GO:0015914", "GO:0032365", "GO:0170036" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26285\" xsd:anyURI" ]
ew
2024-01-10T00:03:13Z
false
true
2
GO:0170047
170,047
virus-like capsid
cellular_component
A protein coat that surrounds nucleic acid to form a structure similar to a virus capsid. Virus-like capsids are non-infectious and are encoded by endogenous (non-viral) genes. Fly and tetrapod Arc (ancestrally-related to retrotransposon Gag) are examples of proteins that can self-assemble into capsid-like structures w...
[ "PMID:29328916" ]
null
[ "virus-like particle" ]
[ "NARROW" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[ "GO:0110165" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26842\" xsd:anyURI" ]
ew
2024-01-26T21:31:41Z
false
true
7
GO:0170048
170,048
D-alanine import across plasma membrane
biological_process
The directed import of D-alanine from the extracellular region across the plasma membrane and into the cytosol.
[ "PMID:22418438", "PMID:25425233" ]
null
[ "D-alanine import", "D-alanine import into cell", "D-alanine uptake" ]
[ "BROAD", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0042941" ]
[]
[]
[]
[ "GO:0042941" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/26844\" xsd:anyURI" ]
ew
2024-01-26T22:35:49Z
false
true
7
GO:0170049
170,049
box C/D RNP complex
cellular_component
A ribonucleoprotein complex consisting of a box C/D type snRNA and three (Archaea) or four (Eukaryotes) core proteins that have diverse functions, including site-specific methylation of rRNA and processing rRNA.
[ "PMID:28505386", "PMID:30254138" ]
null
[ "SNORD ribonucleoprotein complex", "SNORNP" ]
[ "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0005732" ]
[]
[]
[]
[ "GO:0005732" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11686\" xsd:anyURI" ]
ew
2024-02-02T21:26:03Z
false
true
5
GO:0170050
170,050
box C/D methylation guide RNP complex
cellular_component
A ribonucleoprotein complex containing a box C/D type snoRNA and three (Archaea) or four (Eukaryotes) core proteins that is capable of methylation of target RNAs.
[ "PMID:28505386", "PMID:30254138" ]
null
[]
[]
[]
[]
[]
[ "GO:0170049" ]
[]
[]
[]
[ "GO:0170049" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11686\" xsd:anyURI" ]
ew
2024-02-02T21:27:11Z
false
true
6
GO:0170051
170,051
box C/D methylation guide scaRNP complex
cellular_component
A ribonucleoprotein complex containing a small CB-specific RNA (scaRNA), with a short sequence motif (GU/UG wobble stem) for CB localization that is capable of methylation of target RNAs.
[ "PMID:27775477" ]
null
[]
[]
[]
[]
[]
[ "GO:0170049" ]
[]
[]
[]
[ "GO:0170049" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11686\" xsd:anyURI" ]
ew
2024-02-02T21:27:41Z
false
true
3
GO:0170052
170,052
box C/D pre-rRNA cleavage RNP complex
cellular_component
A ribonucleoprotein complex containing a box C/D type RNA that is involved in pre-rRNA cleavage.
[ "PMID:15367679", "PMID:28505386", "PMID:30254138" ]
null
[]
[]
[]
[]
[]
[ "GO:0170049" ]
[]
[]
[]
[ "GO:0170049" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/11686\" xsd:anyURI" ]
ew
2024-02-02T21:29:50Z
false
true
4
GO:0170053
170,053
nuclease activator activity
molecular_function
Binds to and increases the activity of a nuclease.
[ "PMID:24736845" ]
null
[]
[]
[]
[]
[]
[ "GO:0008047" ]
[ "positively_regulates GO:0004518" ]
[ "positively_regulates" ]
[ "GO:0004518" ]
[ "GO:0004518", "GO:0008047" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27178\" xsd:anyURI" ]
ew
2024-03-05T00:43:33Z
false
true
6
GO:0170054
170,054
ribonuclease activator activity
molecular_function
Binds to and increases the activity of a ribonuclease.
[ "PMID:24736845" ]
null
[ "RNA nuclease activator activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0170053" ]
[ "positively_regulates GO:0004540" ]
[ "positively_regulates" ]
[ "GO:0004540" ]
[ "GO:0004540", "GO:0170053" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27178\" xsd:anyURI" ]
ew
2024-03-05T00:45:50Z
false
true
4
GO:0170055
170,055
lipid transmembrane transporter activity
molecular_function
Enables the transfer of a lipid from one side of a membrane to the other.
[ "GOC:curators" ]
null
[]
[]
[]
[ "gocheck_do_not_annotate" ]
[]
[ "GO:0022857" ]
[]
[]
[]
[ "GO:0022857" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27252\" xsd:anyURI" ]
ew
2024-03-15T18:47:58Z
false
true
2
GO:0170056
170,056
cholesterol 7-desaturase [NAD(P)H] activity
molecular_function
Catalysis of the reaction: cholesterol + H+ + NAD(P)H + O2 = 7-dehydrocholesterol + 2 H2O + NAD(P)+.
[ "EC:1.14.19.21", "PMID:21632547", "PMID:31521708" ]
null
[ "C-7 cholesterol dehydrogenase", "cholesterol 7,8-dehydrogenase" ]
[ "EXACT", "EXACT" ]
[]
[]
[ "EC:1.14.19.21", "MetaCyc:RXN-16379", "RHEA:45024", "RHEA:51644" ]
[ "GO:0070704" ]
[]
[]
[]
[ "GO:0070704" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:1.14.19.21", "skos:exactMatch MetaCyc:RXN-16379", "skos:narrowMatch RHEA:45024", "skos:narrowMatch RHEA:51644", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27381\" xsd:anyURI" ]
ew
2024-03-26T16:57:18Z
false
true
2
GO:0170057
170,057
RNA ligase (GTP) activity
molecular_function
Catalysis of the joining of an RNA with 3'-phosphate or 2',3'-cyclic-phosphate ends to an RNA with 5'-hydroxy ends according to either (i) a 3'-end 3'-phospho-ribonucleotide-RNA + a 5'-end dephospho-ribonucleoside-RNA + GTP = a ribonucleotidyl-ribonucleotide-RNA + diphosphate + GMP; or (ii) a 3'-end 2',3'-cyclophospho-...
[ "EC:6.5.1.8", "PMID:21311021" ]
null
[ "3'-phosphate/5'-hydroxy nucleic acid ligase activity" ]
[ "EXACT" ]
[]
[]
[ "EC:6.5.1.8", "MetaCyc:RXN-17905", "MetaCyc:RXN0-6566", "RHEA:68076", "RHEA:68080" ]
[ "GO:0008452" ]
[]
[]
[]
[ "GO:0008452" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch EC:6.5.1.8", "skos:narrowMatch MetaCyc:RXN-17905", "skos:narrowMatch MetaCyc:RXN0-6566", "skos:narrowMatch RHEA:68076", "skos:narrowMatch RHEA:68080", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27418\" xsd:anyURI" ]
ew
2024-03-26T23:34:04Z
false
true
7
GO:0170060
170,060
microtubule destabilizing activity
molecular_function
A protein-containing complex destabilizing activity that promotes microtubule catastrophe (transition from microtubule growth to microtubule shrinkage).
[ "PMID:29858272", "PMID:36435910" ]
null
[ "microtubule catastrophe inducing activity", "microtubule catastrophe promoting activity" ]
[ "BROAD", "BROAD" ]
[]
[]
[]
[ "GO:0140776" ]
[]
[]
[]
[ "GO:0140776" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25274\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29587\" xsd:anyURI" ]
ew
2024-10-21T18:05:48Z
false
true
9
GO:0170062
170,062
nutrient storage
biological_process
The accumulation and maintenance in cells or tissues of a nutrient, a substance that is used by an organism to survive, to grow, and to reproduce; such as proteins, vitamins, and minerals. Nutrient reserves can be accumulated for mobilization and utilization when needed.
[ "GOC:ew" ]
null
[]
[]
[]
[]
[]
[ "GO:0009987" ]
[]
[]
[]
[ "GO:0009987" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/17075\" xsd:anyURI" ]
ew
2024-12-02T22:32:15Z
false
true
2
GO:0170063
170,063
transmembrane transport from lysosomal lumen to cytosol
biological_process
The directed movement of a solute from the lysosomal lumen across the lysosomal membrane and into the cytosol.
[ "PMID:26631267" ]
null
[ "export from lysosome lumen to cytosol" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0007041", "GO:0010496", "GO:0034486" ]
[]
[]
[]
[ "GO:0007041", "GO:0010496", "GO:0034486" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/20070\" xsd:anyURI" ]
ew
2024-12-09T20:53:08Z
false
true
1
GO:0170064
170,064
lysosome fission
biological_process
The process by which lysosomes undergo budding and fission to maintain their steady-state number, shape, size, composition and function, and to accomplish regeneration.
[ "PMID:31171420", "PMID:38538795" ]
null
[]
[]
[]
[]
[]
[ "GO:0048285" ]
[]
[]
[]
[ "GO:0048285" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29628\" xsd:anyURI" ]
ew
2025-01-31T20:15:44Z
false
true
3
GO:0170066
170,066
negative regulation of polyamine biosynthetic process
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
[ "PMID:9769097" ]
null
[]
[]
[]
[]
[]
[ "GO:0009890", "GO:0010967", "GO:0033239" ]
[ "negatively_regulates GO:0006596" ]
[ "negatively_regulates" ]
[ "GO:0006596" ]
[ "GO:0006596", "GO:0009890", "GO:0010967", "GO:0033239" ]
[ "GO:0065007", "negatively_regulates GO:0006596" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29814\" xsd:anyURI" ]
ew
2025-03-11T19:55:32Z
false
true
4
GO:0170067
170,067
obsolete L-arginine biosynthetic process via N-acetyl-L-citrulline
biological_process
OBSOLETE. The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound N-acetyl-L-citrulline.
[ "PMID:16585758" ]
The reason for obsoletion is that this term represents a GO-CAM model.
[ "arginine biosynthesis via N-acetyl intermediates", "arginine biosynthesis, N-acetylated pathway" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[]
[ "GO:0006526" ]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29602\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31525\" xsd:anyURI" ]
ew
2025-03-14T17:04:09Z
true
true
5
GO:0170069
170,069
geranylgeranyltransferase-III complex
cellular_component
A protein-containing complex that catalyzes the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a mono-farnsylated substrate. In humans, the complex is comprised of a prenyltransferase alpha subunit, PTAR1 and beta subunit, RabGGTB, while in budding yeast the prenyltransferase complex contains ...
[ "PMID:32128853", "PMID:33035318", "PMID:35628237", "PMID:40049413" ]
null
[ "geranylgeranyltransferase type 3 complex", "geranylgeranyltransferase type-3 complex", "GGT3", "GGTase-3 complex", "GGTase-III complex", "GGTase3 complex", "type-III geranylgeranyltransferase complex" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1990234" ]
[ "part_of GO:0005829" ]
[ "part_of" ]
[ "GO:0005829" ]
[ "GO:0005829", "GO:1990234" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29943\" xsd:anyURI" ]
ew
2025-03-21T19:57:46Z
false
true
2
GO:0170070
170,070
negative regulation of mitochondrial transcription
biological_process
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription occurring in the mitochondrion.
[ "PMID:23300484" ]
null
[]
[]
[]
[]
[]
[ "GO:0045892", "GO:1903108" ]
[ "negatively_regulates GO:0006390" ]
[ "negatively_regulates" ]
[ "GO:0006390" ]
[ "GO:0006390", "GO:0045892", "GO:1903108" ]
[ "GO:0065007", "negatively_regulates GO:0006390" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/29938\" xsd:anyURI" ]
ew
2025-06-09T17:43:39Z
false
true
7
GO:0170071
170,071
CROP complex
cellular_component
A complex involved in membrane fission during protein exchange in endo-lysosomal compartments. CROP joins members of two protein families: the peripheral subunits of retromer, a coat forming endosomal transport carriers, and membrane inserting PROPPINs.
[ "PMID:35466426" ]
null
[ "Cutting Retromer-On-PROPPIN" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[ "GO:0032991" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30686\" xsd:anyURI" ]
ew
2025-08-12T21:56:57Z
false
true
2
GO:0170074
170,074
RADAR pathway
biological_process
A quality control pathway that degrades peroxisomal matrix protein receptors when the recycling machinery is blocked. When recycling to the cytosol fails, cargo-free receptors accumulate at the peroxisomal membrane, where they are polyubiquitinated and subsequently degraded by the ubiquitin-proteasome system (UPS).
[ "PMID:16390998", "PMID:17011644", "PMID:41076631" ]
null
[ "Receptor Accumulation and Degradation in the Absence of Recycling" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0043161" ]
[]
[]
[]
[ "GO:0043161" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31570\" xsd:anyURI" ]
ew
2026-02-17T22:02:27Z
false
true
9
GO:0170075
170,075
negative regluation of nuclear-transribed mRNA catabolic process, no-go decay
biological_process
Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, no-go decay.
[ "PMID:41607283" ]
null
[ "negative regulation of no-go decay", "negative regulation of no-go mRNA decay", "negative regulation of nuclear-transcribed mRNA breakdown, no-go decay", "negative regulation of nuclear-transcribed mRNA catabolism, no-go decay", "negative regulation of nuclear-transcribed mRNA degradation, no-go decay" ]
[ "EXACT", "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:1902373" ]
[ "negatively_regulates GO:0070966" ]
[ "negatively_regulates" ]
[ "GO:0070966" ]
[ "GO:0070966", "GO:1902373" ]
[ "GO:0065007", "negatively_regulates GO:0070966" ]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31747\" xsd:anyURI" ]
ew
2026-03-23T21:12:37Z
false
true
2
GO:0180000
180,000
histone methyltransferase inhibitor activity
molecular_function
Binds to and stops, prevents or reduces the activity of a histone methyltransferase.
[ "PMID:30923826" ]
null
[]
[]
[]
[]
[]
[ "GO:0004857" ]
[]
[]
[]
[ "GO:0004857" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24785\" xsd:anyURI" ]
vw
2023-01-27T12:31:33Z
false
true
1
GO:0180001
180,001
cyclic-di-AMP binding
molecular_function
Binding to a cyclic di-AMP nucleotide.
[ "PMID:32843560", "PMID:36629470" ]
null
[ "cyclic dimeric adenosine monophosphate binding" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0030551", "GO:0032559" ]
[]
[]
[]
[ "GO:0030551", "GO:0032559" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25203\" xsd:anyURI" ]
vw
2023-03-31T08:52:09Z
false
true
2
GO:0180002
180,002
renal zinc excretion
biological_process
The elimination of zinc ions from peritubular capillaries (or surrounding hemolymph in invertebrates) into the renal tubules to be incorporated subsequently into the urine.
[ "PMID:28196538" ]
null
[ "renal zinc ion excretion", "renal zinc secretion" ]
[ "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0097254" ]
[]
[]
[]
[ "GO:0097254" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24307\" xsd:anyURI" ]
vw
2022-11-01T17:35:12Z
false
true
5
GO:0180003
180,003
S-adenosyl-L-methionine:S-adenosyl-L-homocysteine antiporter activity
molecular_function
Catalysis of the reaction: S-adenosyl-L-homocysteine(out) + S-adenosyl-L-methionine(in) = S-adenosyl-L-homocysteine(in) + S-adenosyl-L-methionine(out).
[ "PMID:14674884", "PMID:34375635" ]
null
[]
[]
[]
[]
[ "RHEA:75479" ]
[ "GO:0000095", "GO:0015179", "GO:0015211", "GO:0015297", "GO:0072349" ]
[]
[]
[]
[ "GO:0000095", "GO:0015179", "GO:0015211", "GO:0015297", "GO:0072349" ]
[]
[]
[]
[]
[]
[ "skos:exactMatch RHEA:75479", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24887\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/30193\" xsd:anyURI" ]
vw
2023-02-10T13:06:12Z
false
true
1
GO:0180004
180,004
RNA polymerase II CTD heptapeptide repeat Y1 phosphatase activity
molecular_function
Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-tyrosine (consensus YSPTSPS)(position 1) + H2O = RNA polymerase II large subunit + phosphate.
[ "PMID:22622228" ]
null
[ "RNA polymerase II C-terminal domain Y1 phosphatase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.3.16", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
vw
2023-02-17T14:58:57Z
false
true
8
GO:0180005
180,005
RNA polymerase II CTD heptapeptide repeat T4 phosphatase activity
molecular_function
Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-threonine (consensus YSPTSPS)(position 4) + H2O = RNA polymerase II large subunit + phosphate.
[ "PMID:22622228" ]
null
[ "RNA polymerase II C-terminal domain T4 phosphatase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.3.16", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
vw
2023-02-17T15:02:16Z
false
true
2
GO:0180006
180,006
RNA polymerase II CTD heptapeptide repeat S2 phosphatase activity
molecular_function
Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 2) + H2O = RNA polymerase II large subunit + phosphate.
[ "PMID:22622228" ]
null
[ "RNA polymerase II C-terminal domain S2 phosphatase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.3.16", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
vw
2023-02-17T15:05:10Z
false
true
9
GO:0180007
180,007
RNA polymerase II CTD heptapeptide repeat S5 phosphatase activity
molecular_function
Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 5) + H2O = RNA polymerase II large subunit + phosphate.
[ "PMID:22622228" ]
null
[ "RNA polymerase II C-terminal domain S5 phosphatase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.3.16", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
vw
2023-02-17T15:09:01Z
false
true
6
GO:0180008
180,008
RNA polymerase II CTD heptapeptide repeat S7 phosphatase activity
molecular_function
Catalysis of the reaction: RNA polymerase II large subunit CTD heptapeptide repeat--phospho-L-serine (consensus YSPTSPS)(position 7) + H2O = RNA polymerase II large subunit + phosphate.
[ "PMID:22622228" ]
null
[ "RNA polymerase II C-terminal domain S7 phosphatase activity" ]
[ "EXACT" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[ "GO:0008420" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch EC:3.1.3.16", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24910\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/28520\" xsd:anyURI" ]
vw
2023-02-17T15:10:24Z
false
true
2
GO:0180009
180,009
broad specificity neutral L-amino acid:basic L-amino acid antiporter activity
molecular_function
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: basic L-amino acid(in) + neutral L-amino acid(out) = basic L-amino acid(in) + neutral L-amino acid(out).
[ "PMID:23506863", "PMID:8663357" ]
null
[ "neutral L-amino acid:cationic L-amino acid antiporter activity", "neutral L-amino acid:dibasic L-amino acid antiporter activity", "neutral L-amino acid:positively-charged polar L-amino acid antiporter activity", "system b(0,+)-type activity" ]
[ "EXACT", "EXACT", "EXACT", "RELATED" ]
[]
[]
[ "RHEA:71059", "RHEA:71067", "RHEA:71071", "RHEA:71075" ]
[ "GO:0015174", "GO:0015175", "GO:0015297" ]
[]
[]
[]
[ "GO:0015174", "GO:0015175", "GO:0015297" ]
[]
[]
[]
[]
[]
[ "skos:narrowMatch RHEA:71059", "skos:narrowMatch RHEA:71067", "skos:narrowMatch RHEA:71071", "skos:narrowMatch RHEA:71075", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24497\" xsd:anyURI" ]
vw
2023-04-06T09:22:30Z
false
true
7
GO:0180010
180,010
co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway
biological_process
Any process involved in transcription termination-coupled 3' processing of RNA polymerase II mRNA transcripts by the 3' end cleavage and addition of a poly(A) tail.
[ "PMID:31499460" ]
null
[ "cotranscriptional 3' processing of RNA polymerase II mRNA transcripts", "mRNA polyadenylation" ]
[ "EXACT", "RELATED" ]
[]
[]
[ "Reactome:R-HSA-9770562 \"mRNA Polyadenylation\"" ]
[ "GO:0031124", "GO:0180012" ]
[]
[]
[]
[ "GO:0031124", "GO:0180012" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24921\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/27004\" xsd:anyURI" ]
vw
2023-02-23T11:56:19Z
false
true
7
GO:0180012
180,012
co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway
biological_process
Any process involved in transcription termination-coupled 3' processing of RNA polymerase II RNA transcripts by 3' end cleavage and addition of a poly(A) tail.
[ "PMID:31499460" ]
null
[ "cotranscriptional 3'-end processing of RNA polymerase II transcripts" ]
[ "EXACT" ]
[]
[]
[ "PMID:31499460" ]
[ "GO:0031123" ]
[]
[]
[]
[ "GO:0031123" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/24921\" xsd:anyURI" ]
vw
2023-02-23T12:18:59Z
false
true
9
GO:0180013
180,013
lysophosphatidylserine flippase activity
molecular_function
Catalysis of the movement of a lysophosphatidylserine from the exoplasmic to the cytosolic leaflet of a membrane, using energy from the hydrolysis of ATP.
[ "PMID:34645814" ]
null
[]
[]
[]
[]
[]
[ "GO:0140333" ]
[]
[]
[]
[ "GO:0140333" ]
[]
[]
[]
[]
[]
[ "skos:broadMatch RHEA:66132" ]
vw
2023-02-23T14:32:13Z
false
true
2
GO:0180014
180,014
protein-tRNA adaptor activity
molecular_function
The binding activity of a protein that brings together another protein and a tRNA, permitting those molecules to function in a coordinated way.
[ "PMID:31048492" ]
null
[ "tRNA carrier" ]
[ "RELATED" ]
[]
[]
[]
[ "GO:0140517" ]
[]
[]
[]
[ "GO:0140517" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25046\" xsd:anyURI" ]
vw
2023-03-02T11:03:26Z
false
true
1
GO:0180015
180,015
nucleoside import across plasma membrane
biological_process
The directed movement of nucleoside from outside of a cell, across the plasma membrane and into the cytosol.
[ "PMID:21998139", "PMID:30658162" ]
null
[]
[]
[]
[]
[]
[ "GO:0098739", "GO:1901642" ]
[]
[]
[]
[ "GO:0098739", "GO:1901642" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25031\" xsd:anyURI" ]
vw
2023-03-02T16:44:33Z
false
true
2
GO:0180016
180,016
SUMO ligase regulator activity
molecular_function
Binds to and modulates the activity of a SUMO ligase.
[ "PMID:19363481", "PMID:33446573" ]
null
[]
[]
[]
[]
[]
[ "GO:0055103" ]
[]
[]
[]
[ "GO:0055103" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25052\" xsd:anyURI" ]
vw
2023-03-03T15:33:58Z
false
true
9
GO:0180018
180,018
cytoplasmic polyadenylation-dependent RNA catabolic process
biological_process
The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of an RNA molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.
[ "PMID:20368444" ]
null
[]
[]
[]
[]
[]
[ "GO:0043633" ]
[]
[]
[]
[ "GO:0043633" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25009\" xsd:anyURI" ]
vw
2023-05-15T11:18:39Z
false
true
7
GO:0180019
180,019
Knl1/Spc105 complex
cellular_component
A kinetochore subcomplex that binds to centromeric chromatin and forms part of the outer kinetochore. It is involved in kinetochore-microtubule binding, recruiting microtubule binding outer kinetochore subunits. It is essential for kinetochore binding by components of the spindle assembly checkpoint. In humans, budding...
[ "PMID:14565975", "PMID:19893618" ]
null
[ "KNL-1 complex", "KNL1 complex", "Spc105 complex", "Spc105p/Kre28p complex" ]
[ "EXACT", "EXACT", "EXACT", "EXACT" ]
[]
[]
[]
[ "GO:0032991" ]
[ "part_of GO:0000940" ]
[ "part_of" ]
[ "GO:0000940" ]
[ "GO:0000940", "GO:0032991" ]
[]
[]
[]
[]
[]
[ "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/25544\" xsd:anyURI", "term_tracker_item \"https://github.com/geneontology/go-ontology/issues/31052\" xsd:anyURI" ]
vw
2023-06-16T09:53:26Z
false
true
2