ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000165794
SLC39A2
Solute carrier family 39 member 2
[ "Q9NP94" ]
14
20999255-21001871
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030489", "HPA073231" ]
[ "ZIP2" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport", "Zinc transport" ]
[]
[]
[ "Plasma membrane" ]
[ "Cytoplasmic bodies" ]
[]
[]
Approved
Uncertain
null
45
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,479
1
ENSG00000165795
NDRG2
NDRG family member 2
[ "Q9UN36" ]
14
21016763-21070872
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002896", "HPA003590", "CAB017491" ]
[ "KIAA1248", "SYLD" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Differentiation", "Neurogenesis", "Wnt signaling pathway" ]
[ "Developmental protein" ]
[ "Tumor suppressor" ]
[ "Centriolar satellite" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Approved
Enhanced
null
4
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 19: Astrocytes - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
11
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
11,480
2
ENSG00000165799
RNASE7
Ribonuclease A family member 7
[ "Q9H1E1" ]
14
21042316-21044234
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005690", "CAB062560", "CAB068225" ]
[ "RAE1" ]
[ "Predicted secreted proteins" ]
[]
[ "Antibiotic", "Antimicrobial", "Endonuclease", "Hydrolase", "Nuclease" ]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "Enzyme" ]
null
Enhanced
null
16
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 84: Apical squamous epithelium - Cornification
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,481
1
ENSG00000165802
NSMF
NMDA receptor synaptonuclear signaling and neuronal migration factor
[ "Q6X4W1" ]
9
137447570-137459334
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044316" ]
[ "NELF" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Hypogonadotropic hypogonadism", "Kallmann syndrome" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
1
null
null
Cluster 25: Non-specific - Unknown function
Cluster 51: Neurons - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in all
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
4
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
11,483
5
ENSG00000165805
C12orf50
Chromosome 12 open reading frame 50
[ "Q8NA57" ]
12
87980035-88034037
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FLJ35821" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
2
null
null
null
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in single
473
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,485
6
ENSG00000165806
CASP7
Caspase 7
[ "P55210" ]
10
113679162-113730907
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025563", "HPA069167" ]
[ "CMH-1", "ICE-LAP3", "MCH3" ]
[ "Cancer-related genes", "Enzymes", "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[ "Allosteric enzyme", "Hydrolase", "Protease", "RNA-binding", "Thiol protease" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm", "Nucleoli fibrillar center" ]
[ "Plasma membrane" ]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Enhanced
null
31
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 39: Astrocytes - Mixed function
Cluster 31: Non-specific - Antiviral immune response
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
11,486
3
ENSG00000165807
PPP1R36
Protein phosphatase 1 regulatory subunit 36
[ "Q96LQ0" ]
14
64549920-64589381
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA077492" ]
[ "C14orf50" ]
[ "Predicted intracellular proteins" ]
[]
[ "Protein phosphatase inhibitor" ]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
Cluster 28: Oligodendrocytes - Mixed function
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 21: Testis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
5
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
11,487
6
ENSG00000165810
BTNL9
Butyrophilin like 9
[ "Q6UXG8" ]
5
181040225-181061521
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043429" ]
[ "BTN8", "FLJ32535" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Nuclear membrane" ]
[ "Vesicles" ]
[]
[]
Approved
null
null
null
null
null
Cluster 17: B-cells - Immunoglobulins
Cluster 49: Hindbrain - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
3
4
1
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
11,488
1
ENSG00000165813
CCDC186
Coiled-coil domain containing 186
[ "Q7Z3E2" ]
10
114120862-114174232
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014569", "HPA018019" ]
[ "C10orf118", "CCCP-1", "FLJ10188", "FLJ35301", "golgin104" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 5: Non-specific - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 8: Pancreas - Proteolysis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
11,489
8
ENSG00000165816
VWA2
Von Willebrand factor A domain containing 2
[ "Q5GFL6" ]
10
114239254-114294489
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037847" ]
[ "AMACO", "CCSP-2", "FLJ16213", "FLJ45857", "NET42" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
null
Uncertain
null
1
null
null
null
Cluster 6: Non-specific - Immune response
Cluster 32: Non-specific - Cell proliferation
Cluster 104: Brain endothelial cells - Blood brain barrier
Cluster 82: Salivary gland - Secretion
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,490
1
ENSG00000165819
METTL3
Methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit
[ "Q86U44" ]
14
21498133-21511342
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA079662" ]
[ "M6A", "MT-A70", "Spo8" ]
[ "Enzymes", "Essential proteins", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Biological rhythms", "Differentiation", "DNA damage", "Immunity", "Innate immunity", "Oogenesis", "Spermatogenesis" ]
[ "Methyltransferase", "RNA-binding", "Transferase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Nuclear bodies", "Golgi apparatus" ]
[]
[]
Supported
null
null
23
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 30: Non-specific - Gene expression regulation
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
11,491
4
ENSG00000165821
SALL2
Spalt like transcription factor 2
[ "Q9Y467" ]
14
21521080-21537216
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA004162" ]
[ "Hsal2", "KIAA0360", "ZNF795" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
10
null
null
Cluster 30: Non-specific - DNA binding
Cluster 19: Astrocytes - Mixed function
Cluster 34: Testis cancer - Unknown function
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 65: Brain - Transcription
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
11,492
8
ENSG00000165828
PRAP1
Proline rich acidic protein 1
[ "Q96NZ9" ]
10
133347368-133352683
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038713", "HPA052451" ]
[ "UPA" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to digestive system" ]
[ "No annotated function" ]
null
Supported
null
7
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 77: Intestine - Digestion
Group enriched
Detected in many
5
Group enriched
Detected in many
5
Cancer enriched
Detected in many
5
Cell type enriched
Detected in some
16
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,493
4
ENSG00000165832
TRUB1
TruB pseudouridine synthase family member 1
[ "Q8WWH5" ]
10
114938195-114977676
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA037914", "HPA057552" ]
[ "PUS4" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "mRNA processing", "tRNA processing" ]
[ "Isomerase" ]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
5
null
null
Cluster 24: Non-specific - Transcription
Cluster 14: Neurons - Synaptic function
Cluster 52: Non-specific - Mitochondria
Cluster 18: Adrenal cortex cells - Steroidogensis
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
11,494
2
ENSG00000165841
CYP2C19
Cytochrome P450 family 2 subfamily C member 19
[ "P33261" ]
10
94762681-94855547
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015066", "HPA074424" ]
[ "CPCJ", "CYP2C", "P450IIC19" ]
[ "Cancer-related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Fatty acid metabolism", "Lipid metabolism" ]
[ "Monooxygenase", "Oxidoreductase" ]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Uncertain
Supported
null
2
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
6
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
11,496
8
ENSG00000165861
ZFYVE1
Zinc finger FYVE-type containing 1
[ "Q9HBF4" ]
14
72969451-73027131
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002898" ]
[ "DFCP1", "KIAA1589", "PPP1R172", "TAFF1", "ZNFN2A1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Supported
Approved
null
2
null
null
Cluster 25: Non-specific - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 7: Non-specific - Transcription
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
11,497
7
ENSG00000165863
C10orf82
Chromosome 10 open reading frame 82
[ "Q8WW14" ]
10
116663696-116670264
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043022" ]
[ "Em:AC016825.4", "MGC33547" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Uncertain
null
null
null
Yes
null
Cluster 46: Basophils - Proteolysis
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 27: Breast cancer - Unknown function
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in some
19
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
8
Immune cell enriched
Detected in single
103
0
0
0
[]
[]
[]
11,498
8
ENSG00000165868
HSPA12A
Heat shock protein family A (Hsp70) member 12A
[ "O43301" ]
10
116671192-116850251
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011273", "HPA073244" ]
[ "FLJ13874", "KIAA0417" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
32
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 15: Kidney cancer - Membrane components
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
14
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
11,499
5
ENSG00000165879
FRAT1
FRAT regulator of WNT signaling pathway 1
[ "Q92837" ]
10
97319271-97321915
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB046472", "HPA055258" ]
[]
[ "Predicted intracellular proteins" ]
[ "Wnt signaling pathway" ]
[]
[ "Proto-oncogene" ]
[ "Vesicles", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
9
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
5
2
0
2
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma" ]
11,500
7
ENSG00000165886
UBTD1
Ubiquitin domain containing 1
[ "Q9HAC8" ]
10
97498924-97571206
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA034825" ]
[ "FLJ11807" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
Approved
Uncertain
null
23
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 19: Astrocytes - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 47: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
11,501
1
ENSG00000165887
ANKRD2
Ankyrin repeat domain 2
[ "Q9GZV1" ]
10
97572499-97583884
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040842", "HPA040884" ]
[ "ARPP" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Enhanced
Enhanced
null
6
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 15: Kidney cancer - Membrane components
Cluster 55: Myocytes - Oxidative muscle function
Cluster 30: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in some
44
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
5
Group enriched
Detected in some
10
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,502
6
ENSG00000165891
E2F7
E2F transcription factor 7
[ "Q96AV8" ]
12
77021248-77065569
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA063960" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Cell cycle", "DNA damage", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[ "Primary cilium", "Primary cilium tip", "Cytosol" ]
[]
[]
Supported
null
null
6
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 46: Brainstem - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
3
2
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
11,503
1
ENSG00000165898
ISCA2
Iron-sulfur cluster assembly 2
[ "Q86U28" ]
14
74493756-74497106
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030492" ]
[ "HBLD1", "ISA2" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "Primary mitochondrial disease" ]
[]
[]
[]
[]
null
Approved
null
37
null
null
Cluster 22: Eosinophils - Transcription
Cluster 21: Non-specific - Metabolism
Cluster 30: Non-specific - Gene expression regulation
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
11,505
1
ENSG00000165899
OTOGL
Otogelin like
[ "Q3ZCN5" ]
12
80099537-80380880
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040364", "HPA053392" ]
[ "C12orf64", "FLJ90579" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[ "Deafness", "Non-syndromic deafness" ]
[ "Cytosol" ]
[]
[ "Secreted in other tissues" ]
[ "No annotated function" ]
Approved
Uncertain
null
1
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 72: Kidney - Transmembrane transport
Group enriched
Detected in some
4
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
11,506
3
ENSG00000165905
LARGE2
LARGE xylosyl- and glucuronyltransferase 2
[ "Q8N3Y3" ]
11
45921621-45929096
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA056621" ]
[ "FLJ35207", "GYLTL1B", "PP5656" ]
[ "Predicted intracellular proteins" ]
[]
[ "Glycosyltransferase", "Multifunctional enzyme", "Transferase" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Approved
null
9
null
null
Cluster 34: B-cells - Unknown function
Cluster 36: Choroid plexus - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
4
Immune cell enhanced
Detected in some
null
3
0
3
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
11,507
2
ENSG00000165912
PACSIN3
Protein kinase C and casein kinase substrate in neurons 3
[ "Q9UKS6" ]
11
47177522-47186443
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039480", "HPA043904" ]
[ "SDPIII" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Endocytosis" ]
[]
[]
[ "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Supported
Approved
Approved
46
null
null
null
Cluster 13: Oligodendrocytes - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 30: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in many
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
11,508
2
ENSG00000165914
TTC7B
Tetratricopeptide repeat domain 7B
[ "Q86TV6" ]
14
90524564-90816479
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058363", "HPA059577" ]
[ "TTC7L1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[]
[]
[]
Supported
Enhanced
null
10
null
null
Cluster 22: Eosinophils - Transcription
Cluster 32: Cerebral cortex - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
7
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
11,509
4
ENSG00000165915
SLC39A13
Solute carrier family 39 member 13
[ "Q96H72" ]
11
47407132-47416496
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043971" ]
[ "FLJ25785" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport", "Zinc transport" ]
[]
[ "Ehlers-Danlos syndrome" ]
[]
[]
[]
[]
null
Approved
null
4
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 18: Non-specific - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
11,510
8
ENSG00000165916
PSMC3
Proteasome 26S subunit, ATPase 3
[ "P17980" ]
11
47418769-47426473
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA006065" ]
[ "RPT5", "TBP-1", "TBP1" ]
[ "Disease related genes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[]
[ "Cataract", "Deafness", "Intellectual disability", "Neuropathy" ]
[ "Nucleoplasm", "Cytosol" ]
[ "Nuclear bodies" ]
[]
[]
Approved
Approved
null
202
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 27: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
11,511
3
ENSG00000165917
RAPSN
Receptor associated protein of the synapse
[ "Q13702" ]
11
47437764-47449143
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039475" ]
[ "CMS1D", "CMS1E", "RNF205" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Congenital myasthenic syndrome", "Disease variant" ]
[ "Plasma membrane", "Centrosome", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
3
null
null
null
Cluster 12: Non-specific - Vasculature
Cluster 33: Sarcoma - Muscle contraction
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 19: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in some
23
Cancer enriched
Detected in some
36
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,512
9
ENSG00000165923
AGBL2
AGBL carboxypeptidase 2
[ "Q5U5Z8" ]
11
47659591-47715389
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007718" ]
[ "CCP2", "FLJ23598" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Carboxypeptidase", "Hydrolase", "Metalloprotease", "Protease" ]
[]
[ "Nucleoli", "Basal body", "Cytosol", "Flagellar centriole" ]
[ "Mid piece", "Principal piece", "End piece" ]
[]
[]
Supported
Uncertain
null
1
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 5: Rhabdoid - Unknown function
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Not detected
Not detected
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,513
1
ENSG00000165929
TC2N
Tandem C2 domains, nuclear
[ "Q8N9U0" ]
14
91779746-91867536
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027549" ]
[ "C14orf47", "C2CD1", "FLJ36557", "MTAC2D1", "Tac2-N" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Nuclear bodies" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 27: T-cells - Unknown function
Cluster 39: Astrocytes - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 8: Pancreas - Proteolysis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
11,514
2
ENSG00000165934
CPSF2
Cleavage and polyadenylation specific factor 2
[ "Q9P2I0" ]
14
92121969-92172145
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024238" ]
[ "CPSF100", "KIAA1367" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing" ]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
Supported
null
31
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 50: Non-specific - Nucleic acid binding
Cluster 30: Non-specific - Gene expression regulation
Cluster 17: Non-specific - RNA processing
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
11,515
5
ENSG00000165935
SMCO2
Single-pass membrane protein with coiled-coil domains 2
[ "A6NFE2" ]
12
27446736-27502185
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA014366" ]
[ "C12orf70", "LOC341346" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 46: Skeletal myocytes - Muscle structure & formation
null
Not detected
Not detected
null
Low cancer specificity
Detected in single
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
11,516
2
ENSG00000165943
MOAP1
Modulator of apoptosis 1
[ "Q96BY2" ]
14
93182199-93184923
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000939", "HPA076948" ]
[ "MAP-1", "PNMA4" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis", "Autophagy" ]
[]
[]
[ "Nucleoplasm" ]
[ "Cell Junctions" ]
[]
[]
Approved
Enhanced
null
13
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 14: Neurons - Synaptic function
Cluster 30: Non-specific - Gene expression regulation
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
11,517
8
ENSG00000165948
IFI27L1
Interferon alpha inducible protein 27 like 1
[ "Q96BM0" ]
14
94081301-94103846
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FAM14B" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Other" ]
null
null
null
null
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 42: Choroid plexus - Mitochondria
Cluster 30: Non-specific - Gene expression regulation
Cluster 43: Sertoli cells - Spermatogenesis microenvironment
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Breast Invasive Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
11,518
2
ENSG00000165949
IFI27
Interferon alpha inducible protein 27
[ "P40305" ]
14
94104836-94116695
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA028875" ]
[ "FAM14D", "ISG12", "P27" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Antiviral defense", "Apoptosis", "Host-virus interaction", "Immunity", "Innate immunity", "Transcription", "Transcription regulation" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
1
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 43: Hindbrain - Mixed function
Cluster 31: Non-specific - Antiviral immune response
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 5: Spleen - Immune response
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
11,519
6
ENSG00000165953
SERPINA12
Serpin family A member 12
[ "Q8IW75" ]
14
94487274-94517844
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "OL-64" ]
[ "Predicted secreted proteins" ]
[]
[ "Protease inhibitor", "Serine protease inhibitor" ]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "Enzyme inhibitor" ]
null
null
null
25
null
null
null
null
Cluster 71: Lymphoma - Inflammatory response
Cluster 26: Keratinocytes - Keratinization
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in some
16
Not detected
Not detected
null
Group enriched
Detected in some
5
Cell type enriched
Detected in some
11
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,520
2
ENSG00000165959
CLMN
Calmin
[ "Q96JQ2" ]
14
95181940-95319908
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012634" ]
[ "FLJ12383", "KIAA0500", "KIAA1188" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Actin-binding" ]
[]
[ "Nuclear bodies" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
11
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 11: White matter - Signal transduction
Cluster 69: Skin cancer - ECM organization
Cluster 110: Mural cells - ECM organization
Cluster 21: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
11,521
2
ENSG00000165966
PDZRN4
PDZ domain containing ring finger 4
[ "Q6ZMN7" ]
12
41188320-41574745
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042101" ]
[ "DKFZp434B0417", "FLJ33777", "IMAGE5767589", "LNX4" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Enhanced
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,522
2
ENSG00000165970
SLC6A5
Solute carrier family 6 member 5
[ "Q9Y345" ]
11
20599594-20659285
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB079052" ]
[ "GlyT-2", "GLYT2", "NET1" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Neurotransmitter transport", "Symport", "Transport" ]
[]
[ "Disease variant" ]
[]
[]
[]
[]
null
null
Supported
19
null
null
null
Cluster 43: Hindbrain - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
null
Not detected
Not detected
null
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,523
8
ENSG00000165972
CCDC38
Coiled-coil domain containing 38
[ "Q502W7" ]
12
95867048-95942635
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "FLJ40089" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 56: Non-specific - Sensory perception
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in some
6
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,524
7
ENSG00000165973
NELL1
Neural EGFL like 1
[ "Q92832" ]
11
20669551-21575686
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051535" ]
[ "FLJ45906", "IDH3GL" ]
[ "Predicted secreted proteins" ]
[ "Differentiation" ]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "Other" ]
null
Approved
null
2
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 109: Neurons - Neuronal signaling
Cluster 36: Brain & Liver - Signaling
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
11,525
6
ENSG00000165983
PTER
Phosphotriesterase related
[ "Q96BW5" ]
10
16436943-16513745
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038044", "HPA038045" ]
[]
[ "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
1
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 51: Neurons - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 36: Brain & Liver - Signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
11,526
5
ENSG00000165985
C1QL3
Complement C1q like 3
[ "Q5VWW1" ]
10
16513734-16521879
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA071349" ]
[ "C1ql", "C1QTNF13", "CTRP13", "K100" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Cytosol" ]
[ "Secreted in brain" ]
[ "Complement pathway" ]
Approved
null
null
1
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 10: Brain - Synaptic signal transduction
Group enriched
Detected in some
10
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
11,527
1
ENSG00000165995
CACNB2
Calcium voltage-gated channel auxiliary subunit beta 2
[ "Q08289" ]
10
18140424-18543557
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035326" ]
[ "CACNLB2", "MYSB" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "Transporters" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[ "Calcium channel", "Ion channel", "Voltage-gated channel" ]
[ "Brugada syndrome", "Disease variant", "FDA approved drug targets" ]
[]
[]
[]
[]
null
Enhanced
null
3
null
null
null
Cluster 23: Choroid plexus - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 96: Enteroendocrine cells - Neuropeptide signaling
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
11,528
5
ENSG00000165996
HACD1
3-hydroxyacyl-CoA dehydratase 1
[ "B0YJ81" ]
10
17589032-17617374
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CAP", "PTPLA" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Fatty acid biosynthesis", "Fatty acid metabolism", "Lipid biosynthesis", "Lipid metabolism" ]
[ "Developmental protein", "Lyase" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
null
null
4
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 25: Non-specific - Transcription
Cluster 72: Neuronal - Signal transduction
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 35: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
11
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
11,529
2
ENSG00000165997
ARL5B
ADP ribosylation factor like GTPase 5B
[ "Q96KC2" ]
10
18659431-18681639
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027002" ]
[ "ARL8" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
9
null
null
Cluster 20: Non-specific - DNA binding
Cluster 31: Non-specific - Transcription
Cluster 52: Non-specific - Mitochondria
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
11,530
6
ENSG00000166002
SMCO4
Single-pass membrane protein with coiled-coil domains 4
[ "Q9NRQ5" ]
11
93478472-93543391
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041120" ]
[ "C11orf75", "FN5" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
51
null
Yes
Cluster 10: Non-specific - Membrane trafficking
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 10: Ciliated cells - Ion channel activity
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
11,531
9
ENSG00000166004
CEP295
Centrosomal protein 295
[ "Q9C0D2" ]
11
93661682-93730358
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038595", "HPA038596", "HPA038597" ]
[ "KIAA1731" ]
[ "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[]
[ "Disease variant", "Dwarfism", "Intellectual disability" ]
[]
[]
[]
[]
null
Approved
null
6
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 24: Non-specific - Unknown function
Cluster 27: Non-specific - Cell proliferation
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
11,532
3
ENSG00000166006
KCNC2
Potassium voltage-gated channel subfamily C member 2
[ "Q96PR1" ]
12
75040077-75209839
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA019664", "CAB022571" ]
[ "Kv3.2" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Predicted membrane proteins", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Potassium channel", "Voltage-gated channel" ]
[ "Disease variant", "Epilepsy", "FDA approved drug targets", "Intellectual disability" ]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 27: Breast cancer - Unknown function
Cluster 109: Neurons - Neuronal signaling
Cluster 73: Brain - Neuronal signaling
Tissue enriched
Detected in some
4
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
8
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,533
9
ENSG00000166012
TAF1D
TATA-box binding protein associated factor, RNA polymerase I subunit D
[ "Q9H5J8" ]
11
93729948-93784391
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA030703", "HPA055935", "HPA060385" ]
[ "JOSD3", "MGC5306", "TAF(I)41" ]
[ "Essential proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli", "Mitotic spindle", "Centriolar satellite" ]
[]
[]
Supported
Uncertain
null
35
Yes
No
Cluster 24: Non-specific - Transcription
Cluster 9: Non-specific - Receptor signaling
Cluster 24: Non-specific - Unknown function
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Glioblastoma Multiforme", "Rectum Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
11,534
8
ENSG00000166016
ABTB2
Ankyrin repeat and BTB domain containing 2
[ "Q8N961" ]
11
34150987-34358010
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA020065", "HPA030699" ]
[ "ABTB2A", "BTBD22", "DKFZP586C1619" ]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
Approved
null
5
null
null
Cluster 22: Eosinophils - Transcription
Cluster 45: Non-specific - Mixed function
Cluster 54: Non-specific - Transcription
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
13
0
0
0
[]
[]
[]
11,535
5
ENSG00000166024
R3HCC1L
R3H domain and coiled-coil containing 1 like
[ "Q7Z5L2" ]
10
98134624-98244897
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037367" ]
[ "C10orf28", "GIDRP86", "PSORT" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Nuclear speckles" ]
[]
[]
[]
Approved
Enhanced
null
2
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 55: Non-specific - Transcription
Cluster 35: RS4;11 - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
11,536
4
ENSG00000166025
AMOTL1
Angiomotin like 1
[ "Q8IY63" ]
11
94706431-94876748
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA001196" ]
[ "JEAP" ]
[ "Predicted intracellular proteins" ]
[ "Wnt signaling pathway" ]
[]
[]
[ "Cytosol" ]
[ "Cell Junctions" ]
[]
[]
Approved
Approved
null
25
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
11,537
6
ENSG00000166033
HTRA1
HtrA serine peptidase 1
[ "Q92743" ]
10
122458551-122514907
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036655" ]
[ "ARMD7", "HtrA", "IGFBP5-protease", "PRSS11" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Growth factor binding", "Hydrolase", "Protease", "Serine protease" ]
[ "Age-related macular degeneration", "Disease variant" ]
[ "Plasma membrane" ]
[]
[ "Secreted to blood" ]
[ "Enzyme" ]
Supported
Approved
null
4
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 65: Brain - Transcription
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Stomach Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
11,538
5
ENSG00000166035
LIPC
Lipase C, hepatic type
[ "P11150" ]
15
58410569-58569844
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "HL", "HTGL" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted secreted proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Heparin-binding", "Hydrolase" ]
[ "Disease variant" ]
[]
[]
[ "Secreted to blood" ]
[ "Enzyme" ]
null
null
null
null
null
null
Cluster 33: Non-specific - ATP binding
Cluster 37: Neurons - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
28
Group enriched
Detected in many
5
Group enriched
Detected in many
18
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
11,539
9
ENSG00000166037
CEP57
Centrosomal protein 57
[ "Q86XR8" ]
11
95789965-95832693
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018315", "HPA066403" ]
[ "KIAA0092", "Translokin", "TSP57" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Centrosome" ]
[ "Centriolar satellite", "Cytosol" ]
[]
[]
Supported
Approved
null
16
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 31: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 45: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
11,540
9
ENSG00000166046
TCP11L2
T-complex 11 like 2
[ "Q8N4U5" ]
12
106301929-106347003
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039483", "HPA042188" ]
[ "MGC40368" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes" ]
[ "Nuclear speckles" ]
[]
[]
[]
Supported
Uncertain
null
19
null
null
Cluster 20: Non-specific - DNA binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 41: Striated muscle - Muscle contraction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
11,541
5
ENSG00000166049
PASD1
PAS domain containing repressor 1
[ "Q8IV76" ]
X
151563675-151676739
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011122", "HPA011152" ]
[ "CT63" ]
[ "Predicted intracellular proteins" ]
[ "Biological rhythms" ]
[]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Enhanced
Enhanced
null
null
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in single
151
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
66
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,542
3
ENSG00000166068
SPRED1
Sprouty related EVH1 domain containing 1
[ "Q7Z699" ]
15
38252836-38357249
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042193", "HPA061805" ]
[ "FLJ33903", "PPP1R147" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
315
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 7: Non-specific - Ribosome
Cluster 3: Rhabdoid - Membrane components
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 73: Brain - Neuronal signaling
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]
11,543
3
ENSG00000166069
TMCO5A
Transmembrane and coiled-coil domains 5A
[ "Q8N6Q1" ]
15
37921939-37967724
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA056530", "HPA064017" ]
[ "MGC35118", "TMCO5" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
5
null
null
null
Cluster 18: Non-specific - Mixed function
Cluster 65: Non-specific - Unknown function
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in single
178
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,544
7
ENSG00000166073
GPR176
G protein-coupled receptor 176
[ "Q14439" ]
15
39799008-39920266
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA039943", "HPA039979" ]
[ "Gm1012" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Biological rhythms" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
null
Cluster 1: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 110: Mural cells - ECM organization
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[]
[ "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
11,545
4
ENSG00000166086
JAM3
Junctional adhesion molecule 3
[ "Q9BX67" ]
11
134069071-134152001
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003417", "HPA050434" ]
[ "JAM-3", "JAM-C", "JAMC" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[ "Angiogenesis", "Cell adhesion", "Differentiation", "Spermatogenesis" ]
[]
[ "Disease variant" ]
[ "Golgi apparatus" ]
[]
[ "Secreted to blood" ]
[ "Cell adhesion" ]
Uncertain
Approved
null
6
null
null
Cluster 24: Non-specific - Transcription
Cluster 11: White matter - Signal transduction
Cluster 33: Sarcoma - Muscle contraction
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
11,546
2
ENSG00000166090
IL25
Interleukin 25
[ "Q9H293" ]
14
23372809-23376403
Evidence at protein level
No human protein/transcript evidence
Evidence at protein level
Evidence at protein level
[ "CAB024864" ]
[ "IL-17E", "IL-25", "IL17E" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Cytokine" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Interleukin" ]
null
Uncertain
null
null
null
null
null
null
null
Cluster 46: Skeletal myocytes - Muscle structure & formation
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in single
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,547
5
ENSG00000166105
GLB1L3
Galactosidase beta 1 like 3
[ "Q8NCI6" ]
11
134274245-134319564
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA039916" ]
[ "FLJ90231" ]
[ "Predicted intracellular proteins" ]
[]
[ "Glycosidase", "Hydrolase" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 39: T-cells - T-cell receptor
Cluster 37: Neurons - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
10
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
11
0
0
0
[]
[]
[]
11,549
8
ENSG00000166106
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif 15
[ "Q8TE58" ]
11
130448645-130476645
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042867" ]
[]
[ "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[ "Disease variant" ]
[ "Cytosol" ]
[]
[ "Secreted to extracellular matrix" ]
[ "Enzyme" ]
Approved
Uncertain
null
null
null
null
null
Cluster 12: Non-specific - Vasculature
Cluster 15: Kidney cancer - Membrane components
Cluster 108: Fibroblasts - ECM organization
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
2
0
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
11,550
9
ENSG00000166111
SVOP
SV2 related protein
[ "Q8N4V2" ]
12
108907741-109021068
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA016573" ]
[ "DKFZp761H039" ]
[ "Predicted membrane proteins" ]
[ "Transport" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
null
Cluster 14: Neurons - Synaptic function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 10: Brain - Synaptic signal transduction
Group enriched
Detected in some
10
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,551
9
ENSG00000166118
SPATA19
Spermatogenesis associated 19
[ "Q7Z5L4" ]
11
133840631-133845538
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA040082" ]
[ "CT132", "FLJ25851", "SPAS1", "spergen1" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein" ]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
null
Cluster 71: Lymphoma - Inflammatory response
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
465
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
12
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,552
4
ENSG00000166126
AMN
Amnion associated transmembrane protein
[ "Q9BXJ7" ]
14
102922663-102933596
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA000817" ]
[ "amnionless" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[ "Protein transport", "Transport" ]
[ "Developmental protein" ]
[ "Disease variant" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Transport" ]
null
Approved
null
1
null
null
null
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 26: Kidney & Intestine - Metabolism
Group enriched
Detected in many
9
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
11,554
5
ENSG00000166128
RAB8B
RAB8B, member RAS oncogene family
[ "Q92930" ]
15
63189560-63267776
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
null
null
21
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 21: Non-specific - Metabolism
Cluster 55: Lymphoma - Immune response
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
11,555
1
ENSG00000166130
IKBIP
IKBKB interacting protein
[ "Q70UQ0" ]
12
98613405-98645113
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038677", "HPA038678", "HPA061541" ]
[ "FLJ31051", "IKIP" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum" ]
[ "Nucleoli rim", "Mitochondria" ]
[]
[]
Supported
Enhanced
null
19
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 15: Kidney cancer - Membrane components
Cluster 108: Fibroblasts - ECM organization
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
4
2
3
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
11,556
7
ENSG00000166133
RPUSD2
RNA pseudouridine synthase domain containing 2
[ "Q8IZ73" ]
15
40569299-40574949
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042079", "HPA042194" ]
[ "C15orf19", "C18B11", "FLJ31409", "PUS9" ]
[ "Predicted intracellular proteins" ]
[ "mRNA processing" ]
[ "Isomerase" ]
[]
[ "Nucleoplasm", "Microtubules" ]
[]
[]
[]
Approved
Approved
null
null
null
null
Cluster 24: Non-specific - Transcription
Cluster 34: Non-specific - Mixed function
Cluster 58: Non-specific - Nuclear processes
Cluster 17: Non-specific - RNA processing
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
11,557
3
ENSG00000166135
HIF1AN
Hypoxia inducible factor 1 subunit alpha inhibitor
[ "Q9NWT6" ]
10
100529072-100559998
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048742", "HPA065302", "CAB069903" ]
[ "DKFZp762F1811", "FIH1", "FLJ20615", "FLJ22027" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Dioxygenase", "Oxidoreductase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Supported
null
118
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 32: Cerebral cortex - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 30: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
11,558
5
ENSG00000166136
NDUFB8
NADH:ubiquinone oxidoreductase subunit B8
[ "O95169" ]
10
100523740-100530000
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003886", "HPA065549" ]
[ "ASHI", "CI-ASHI" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted membrane proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[]
[ "Disease variant", "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Enhanced
Supported
null
28
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 14: Neurons - Synaptic function
Cluster 52: Non-specific - Mitochondria
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
11,559
3
ENSG00000166140
ZFYVE19
Zinc finger FYVE-type containing 19
[ "Q96K21" ]
15
40807086-40815084
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040283", "HPA041946" ]
[ "ANCHR", "FLJ14840", "MPFYVE" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division" ]
[]
[ "Ciliopathy", "Disease variant", "Intrahepatic cholestasis", "Proto-oncogene" ]
[]
[]
[]
[]
null
Uncertain
null
10
null
null
Cluster 33: Non-specific - ATP binding
Cluster 45: Non-specific - Mixed function
Cluster 58: Non-specific - Nuclear processes
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
11,560
7
ENSG00000166143
PPP1R14D
Protein phosphatase 1 regulatory inhibitor subunit 14D
[ "Q9NXH3" ]
15
40815451-40828709
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041846" ]
[ "CPI17-like", "FLJ20251", "GBPI-1", "MGC119014", "MGC119016" ]
[ "Predicted intracellular proteins" ]
[]
[ "Protein phosphatase inhibitor" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Tissue enriched
Detected in some
7
Cancer enriched
Detected in some
5
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
11,561
5
ENSG00000166145
SPINT1
Serine peptidase inhibitor, Kunitz type 1
[ "O43278" ]
15
40844018-40858207
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006903", "HPA031178" ]
[ "HAI", "HAI-1", "MANSC2" ]
[ "Cancer-related genes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "Transporters" ]
[]
[ "Protease inhibitor", "Serine protease inhibitor" ]
[ "Cancer-related genes" ]
[ "Plasma membrane", "Cytosol" ]
[ "Nucleoplasm" ]
[ "Secreted to blood" ]
[ "Enzyme inhibitor" ]
Supported
Uncertain
null
17
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 50: Non-specific - Nucleic acid binding
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 84: Apical squamous epithelium - Cornification
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Lung Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
11,562
5
ENSG00000166147
FBN1
Fibrillin 1
[ "P35555" ]
15
48408313-48645721
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002670", "HPA017759", "HPA021057", "CAB058696", "CAB068188", "CAB080202" ]
[ "FBN", "MASS", "MFS1", "OCTD", "SGS", "WMS" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins" ]
[]
[ "Heparin-binding", "Hormone" ]
[ "Aortic aneurysm", "Disease variant", "Dwarfism" ]
[ "Golgi apparatus" ]
[ "Plasma membrane" ]
[ "Secreted to blood" ]
[ "Hormone" ]
Approved
Enhanced
null
8
null
null
null
Cluster 45: Non-specific - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma" ]
11,563
9
ENSG00000166148
AVPR1A
Arginine vasopressin receptor 1A
[ "P37288" ]
12
63142759-63151201
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "AVPR1" ]
[ "FDA approved drug targets", "G-protein coupled receptors", "Plasma proteins", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
null
null
1
null
null
null
Cluster 23: Choroid plexus - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 103: Non-specific - Basic cellular processes
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
10
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Skin Cutaneous Melanoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Skin Cutaneous Melanoma" ]
11,564
3
ENSG00000166152
C16orf78
Chromosome 16 open reading frame 78
[ "Q8WTQ4" ]
16
49373804-49399431
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042150" ]
[ "MGC33367" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Connecting piece", "Mid piece", "Principal piece", "End piece" ]
[]
[]
[]
Approved
null
null
null
null
null
null
null
null
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in single
458
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,565
7
ENSG00000166153
DEPDC4
DEP domain containing 4
[ "Q8N2C3" ]
12
100203669-100267079
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
[ "HPA039323" ]
[ "DEP.4", "FLJ33505" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Microtubules" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 9: Non-specific - Receptor signaling
Cluster 63: Non-specific - Protein processing
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
0
0
0
[]
[]
[]
11,566
1
ENSG00000166159
LRTM2
Leucine rich repeats and transmembrane domains 2
[ "Q8N967" ]
12
1820267-1836753
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA055094", "HPA062745" ]
[]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 11: Neuronal - Sensory perception
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in single
10
Cancer enriched
Detected in single
9
Not detected
Not detected
null
Group enriched
Detected in some
17
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,567
7
ENSG00000166160
OPN1MW2
Opsin 1, medium wave sensitive 2
[ "P0DN77" ]
X
154219756-154233286
Evidence at transcript level
No human protein/transcript evidence
No human protein/transcript evidence
Evidence at transcript level
[]
[]
[ "Predicted membrane proteins" ]
[ "Sensory transduction", "Vision" ]
[ "G-protein coupled receptor", "Photoreceptor protein", "Receptor", "Retinal protein", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
11,568
7
ENSG00000166164
BRD7
Bromodomain containing 7
[ "Q9NPI1" ]
16
50313487-50368988
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042389", "CAB046458", "HPA060171" ]
[ "BP75", "CELTIX1", "SMARCI1" ]
[ "Predicted intracellular proteins" ]
[ "Cell cycle", "Transcription", "Transcription regulation", "Wnt signaling pathway" ]
[]
[ "Tumor suppressor" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
82
null
null
Cluster 41: Basophils - Unknown function
Cluster 13: Oligodendrocytes - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
11,569
9
ENSG00000166165
CKB
Creatine kinase B
[ "P12277" ]
14
103519667-103522833
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001254", "CAB047313" ]
[ "CKBB" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Enzymes", "FDA approved drug targets", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Transferase" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
32
No
No
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 60: Prostate cancer - Unknown function
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
10
2
0
2
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
11,570
5
ENSG00000166166
TRMT61A
TRNA methyltransferase 61A
[ "Q96FX7" ]
14
103529196-103537073
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA024269" ]
[ "C14orf172", "FLJ40452", "GCD14", "Gcd14p", "hTRM61" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "tRNA processing" ]
[ "Methyltransferase", "Transferase" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
null
null
21
null
null
Cluster 33: Non-specific - ATP binding
Cluster 6: Non-specific - Immune response
Cluster 30: Non-specific - Gene expression regulation
Cluster 17: Non-specific - RNA processing
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Prostate Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Prostate Adenocarcinoma" ]
11,571
8
ENSG00000166167
BTRC
Beta-transducin repeat containing E3 ubiquitin protein ligase
[ "Q9Y297" ]
10
101354033-101557321
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031156", "CAB032986" ]
[ "beta-TrCP1", "betaTrCP", "bTrCP", "bTrCP1", "FBXW1A", "Fwd1" ]
[ "Predicted intracellular proteins" ]
[ "Biological rhythms", "Host-virus interaction", "Ubl conjugation pathway", "Wnt signaling pathway" ]
[ "Ligase" ]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
Approved
Approved
null
248
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 14: Neurons - Synaptic function
Cluster 52: Non-specific - Mitochondria
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 46: Brain & retina - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
11,572
8
ENSG00000166169
POLL
DNA polymerase lambda
[ "Q9UGP5" ]
10
101578882-101588270
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA076828" ]
[]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "DNA replication", "DNA synthesis" ]
[ "DNA-binding", "DNA-directed DNA polymerase", "Lyase", "Nucleotidyltransferase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
14
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 32: Cerebral cortex - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 7: Non-specific - Transcription
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
11,573
5
ENSG00000166170
BAG5
BAG cochaperone 5
[ "Q9UL15" ]
14
103556545-103562657
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016429" ]
[]
[ "Disease related genes", "Predicted intracellular proteins" ]
[]
[ "Chaperone" ]
[ "Cardiomyopathy", "Disease variant" ]
[ "Vesicles" ]
[ "Nucleoplasm", "Plasma membrane", "Primary cilium", "Primary cilium tip", "Centrosome", "Basal body" ]
[]
[]
Approved
Enhanced
null
54
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 31: Non-specific - Transcription
Cluster 30: Non-specific - Gene expression regulation
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in all
5
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
11,574
8
ENSG00000166171
DPCD
Deleted in primary ciliary dyskinesia homolog (mouse)
[ "Q9BVM2" ]
10
101570560-101609662
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036603", "HPA036604" ]
[ "DKFZP566F084", "RP11-529I10.4" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Vesicles" ]
[ "Plasma membrane", "Mitotic spindle", "Primary cilium" ]
[]
[]
Approved
Enhanced
null
16
Yes
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 23: Choroid plexus - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
5
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
11,575
8
ENSG00000166173
LARP6
La ribonucleoprotein 6, translational regulator
[ "Q9BRS8" ]
15
70829130-70854157
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020338", "HPA049029" ]
[ "acheron", "FLJ11196" ]
[ "Predicted intracellular proteins" ]
[ "Translation regulation" ]
[ "RNA-binding" ]
[]
[ "Microtubules" ]
[ "Cytokinetic bridge" ]
[]
[]
Approved
Approved
null
4
Yes
No
null
Cluster 11: White matter - Signal transduction
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
11,576
3
ENSG00000166181
API5
Apoptosis inhibitor 5
[ "Q9BZZ5" ]
11
43311963-43344529
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026598" ]
[ "AAC-11", "AAC11", "API5L1" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Enhanced
Approved
null
26
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 34: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 17: Non-specific - RNA processing
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
11,577
3
ENSG00000166183
ASPG
Asparaginase
[ "Q86U10" ]
14
104085686-104115582
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA069761" ]
[ "C14orf76", "hASNase1", "LysoLP" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Acyltransferase", "Hydrolase", "Transferase" ]
[]
[]
[]
[]
[]
null
Enhanced
null
12
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 84: Apical squamous epithelium - Cornification
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
4
Cell type enriched
Detected in many
5
Not detected in immune cells
Not detected
null
2
2
1
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
11,578
7
ENSG00000166188
ZNF319
Zinc finger protein 319
[ "Q9P2F9" ]
16
57994676-58000672
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052584" ]
[ "KIAA1388", "Zfp319" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
19
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 68: Non-specific - Cell cycle regulation
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
11,579
2
ENSG00000166189
HPS6
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3
[ "Q86YV9" ]
10
102065349-102068036
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040687" ]
[ "BLOC2S3", "FLJ22501" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Albinism", "Hermansky-Pudlak syndrome" ]
[ "Cytosol" ]
[ "Vesicles" ]
[]
[]
Supported
Approved
null
6
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 32: Cerebral cortex - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 17: Non-specific - RNA processing
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
11,580
1
ENSG00000166192
SENP8
SUMO peptidase family member, NEDD8 specific
[ "Q96LD8" ]
15
72114258-72143692
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036273" ]
[ "DEN1", "HsT17512", "NEDP1", "PRSC2" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Approved
Approved
null
7
null
null
Cluster 33: Non-specific - ATP binding
Cluster 32: Cerebral cortex - Mixed function
Cluster 58: Non-specific - Nuclear processes
Cluster 65: Non-specific - Cell growth & division
Cluster 72: Kidney - Transmembrane transport
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
11,581
4
ENSG00000166197
NOLC1
Nucleolar and coiled-body phosphoprotein 1
[ "Q14978" ]
10
102152176-102163871
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB032654", "HPA037366", "HPA050388" ]
[ "KIAA0035", "NOPP130", "NOPP140", "P130", "Srp40" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoli fibrillar center" ]
[]
[]
[]
Enhanced
Supported
null
49
No
Yes
Cluster 33: Non-specific - ATP binding
Cluster 31: Non-specific - Transcription
Cluster 52: Non-specific - Mitochondria
Cluster 17: Non-specific - RNA processing
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
11,582
4
ENSG00000166199
ALKBH3
AlkB homolog 3, alpha-ketoglutarate dependent dioxygenase
[ "Q96Q83" ]
11
43880811-43920274
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA009674", "HPA046489" ]
[ "DEPC-1" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "Dioxygenase", "Oxidoreductase" ]
[]
[ "Nucleoplasm" ]
[ "Mitochondria" ]
[]
[]
Supported
Approved
null
15
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 31: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
11,583
6
ENSG00000166200
COPS2
COP9 signalosome subunit 2
[ "P61201" ]
15
49106068-49155661
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016867", "HPA018271", "HPA061071" ]
[ "ALIEN", "CSN2", "TRIP15" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Cytokinetic bridge" ]
[]
[]
Supported
Approved
null
80
Yes
No
Cluster 33: Non-specific - ATP binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 58: Non-specific - Nuclear processes
Cluster 17: Non-specific - RNA processing
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
11,584
3