ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000166206 | GABRB3 | Gamma-aminobutyric acid type A receptor subunit beta3 | [
"P28472"
] | 15 | 26543552-26939539 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | 2 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 11,585 | 9 |
ENSG00000166211 | SPIC | Spi-C transcription factor | [
"Q8N5J4"
] | 12 | 101475336-101486997 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"MGC40611",
"SPI-C"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [] | [] | [] | [] | null | null | null | 2 | null | null | Cluster 40: Monocytes - Innate immune response | null | Cluster 55: Lymphoma - Immune response | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 66: Lymphoid tissue - Immune response | Tissue enriched | Detected in some | 14 | Cancer enriched | Detected in single | 9 | Cancer enhanced | Detected in single | null | Cell type enriched | Detected in some | 4 | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 11,586 | 8 |
ENSG00000166220 | TBATA | Thymus, brain and testes associated | [
"Q96M53"
] | 10 | 70771238-70785401 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"C10orf27",
"FLJ32820",
"spatial"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Spermatogenesis"
] | [
"Developmental protein"
] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | null | Cluster 27: Breast cancer - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 80: Thymus - Adaptive immune response | Tissue enriched | Detected in some | 11 | Not detected | Not detected | null | Cancer enriched | Detected in single | 19 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,587 | 8 |
ENSG00000166224 | SGPL1 | Sphingosine-1-phosphate lyase 1 | [
"O95470"
] | 10 | 70815905-70895816 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021125",
"HPA023086"
] | [
"SPL"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Lipid metabolism",
"Sphingolipid metabolism"
] | [
"Lyase"
] | [
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Enhanced | null | 69 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 39: Astrocytes - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 11,588 | 9 |
ENSG00000166225 | FRS2 | Fibroblast growth factor receptor substrate 2 | [
"Q8WU20"
] | 12 | 69470349-69579793 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038323",
"HPA073385"
] | [
"FRS2A",
"FRS2alpha",
"SNT-1",
"SNT1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cell Junctions"
] | [] | [] | [] | Uncertain | null | null | 23 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 61: BICR 18 - Protein kinases | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 11,589 | 5 |
ENSG00000166226 | CCT2 | Chaperonin containing TCP1 subunit 2 | [
"P78371"
] | 12 | 69585426-69601570 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003197",
"HPA003198"
] | [
"Cctb"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Chaperone",
"Hydrolase"
] | [] | [
"Cytosol"
] | [
"Connecting piece",
"Mid piece",
"Principal piece"
] | [] | [] | Supported | Enhanced | null | 326 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 38: Non-specific - Transcription | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 11,590 | 7 |
ENSG00000166228 | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase 1 | [
"P61457"
] | 10 | 70882280-70888565 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037575",
"HPA061723"
] | [
"DCOH",
"PCBD",
"PCD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Tetrahydrobiopterin biosynthesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Lyase"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Enhanced | null | 26 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 52: Non-specific - Mitochondria | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 11,591 | 4 |
ENSG00000166233 | ARIH1 | Ariadne RBR E3 ubiquitin protein ligase 1 | [
"Q9Y4X5"
] | 15 | 72474330-72602987 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003295",
"HPA073245"
] | [
"ARI",
"HARI",
"HHARI",
"UBCH7BP"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 54 | null | null | Cluster 32: Basophils - Transcription | Cluster 31: Non-specific - Transcription | Cluster 61: BICR 18 - Protein kinases | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 47: Testis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in some | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 11,592 | 4 |
ENSG00000166246 | DNAAF8 | Dynein axonemal assembly factor 8 | [
"Q8IYS4"
] | 16 | 4734344-4749396 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049468"
] | [
"C16orf71",
"DKFZp686H2240",
"FLJ43261"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 3: Choroid plexus - Cilium | Cluster 27: Breast cancer - Unknown function | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 56: Ciliated tissues - Cilium organization | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 11,593 | 7 |
ENSG00000166250 | CLMP | CXADR like membrane protein | [
"Q9H6B4"
] | 11 | 123069872-123195248 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"ACAM",
"ASAM",
"FLJ22415"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 64: Connective tissue cells - ECM organization | Cluster 103: Non-specific - Basic cellular processes | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 11,594 | 2 |
ENSG00000166257 | SCN3B | Sodium voltage-gated channel beta subunit 3 | [
"Q9NY72"
] | 11 | 123629187-123655244 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078632"
] | [
"HSA243396",
"SCNB3"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Ion transport",
"Sodium transport",
"Transport"
] | [
"Ion channel",
"Sodium channel",
"Voltage-gated channel"
] | [
"Atrial fibrillation",
"Brugada syndrome",
"Disease variant",
"FDA approved drug targets"
] | [
"Plasma membrane",
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Approved | null | null | 128 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 12 | Cancer enriched | Detected in some | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,595 | 2 |
ENSG00000166260 | COX11 | Cytochrome c oxidase copper chaperone COX11 | [
"Q9Y6N1"
] | 17 | 54951902-54968703 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044020"
] | [
"COX11P"
] | [
"Essential proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant",
"Primary mitochondrial disease"
] | [] | [] | [] | [] | null | Approved | null | 7 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 14: Neurons - Synaptic function | Cluster 27: Breast cancer - Unknown function | Cluster 97: Non-specific - Cellular respiration | Cluster 26: Kidney & Intestine - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 11,596 | 8 |
ENSG00000166261 | ZNF202 | Zinc finger protein 202 | [
"O95125"
] | 11 | 123723914-123741675 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA059229"
] | [
"ZKSCAN10",
"ZSCAN42"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoli rim",
"Mitotic chromosome"
] | [
"Nuclear bodies"
] | [] | [] | Approved | null | null | 17 | Yes | No | Cluster 24: Non-specific - Transcription | Cluster 34: Non-specific - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 7 | 0 | 7 | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 11,597 | 1 |
ENSG00000166262 | FAM227B | Family with sequence similarity 227 member B | [
"Q96M60"
] | 15 | 49326962-49620929 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA049774",
"HPA061695"
] | [
"C15orf33",
"FLJ32800"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 41: Basophils - Unknown function | Cluster 46: Brainstem - Mixed function | Cluster 20: Myeloma - Immune response | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 11,598 | 2 |
ENSG00000166263 | STXBP4 | Syntaxin binding protein 4 | [
"Q6ZWJ1"
] | 17 | 54968727-55173632 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB007760",
"HPA022138",
"HPA022888",
"HPA024227"
] | [
"MGC50337",
"Synip"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 10 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 46: Brainstem - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 110: Mural cells - ECM organization | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 11,599 | 2 |
ENSG00000166265 | CYYR1 | Cysteine and tyrosine rich 1 | [
"Q96J86"
] | 21 | 26466209-26573286 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"CAB034921",
"HPA067685"
] | [
"C21orf95"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 47: Endothelial cells - Vasculature | Cluster 12: Bone cancer - Neuronal signaling | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 38 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 11,600 | 6 |
ENSG00000166266 | CUL5 | Cullin 5 | [
"Q93034"
] | 11 | 108008898-108107761 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002185",
"CAB017787"
] | [
"VACM-1"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [
"Receptor"
] | [
"Cancer-related genes"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 150 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 55: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 11,601 | 4 |
ENSG00000166268 | MYRFL | Myelin regulatory factor like | [
"Q96LU7"
] | 12 | 69825227-69959097 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA049340"
] | [
"bcm1377",
"C12orf15",
"C12orf28",
"FLJ25056"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoli"
] | [] | [
"Intracellular and membrane"
] | [
"Other"
] | Approved | Approved | null | null | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 27: Breast cancer - Unknown function | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in some | 9 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,602 | 9 |
ENSG00000166272 | WBP1L | WW domain binding protein 1 like | [
"Q9NX94"
] | 10 | 102743948-102834516 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037635",
"HPA038371"
] | [
"C10orf26",
"FLJ20154",
"OPAL1"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Microtubules"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 15 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 44: Non-specific - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 11,603 | 7 |
ENSG00000166275 | BORCS7 | BLOC-1 related complex subunit 7 | [
"Q96B45"
] | 10 | 102854259-102864961 | Evidence at protein level | Evidence at transcript level | No human protein/transcript evidence | Evidence at protein level | [
"HPA037648",
"HPA077528"
] | [
"C10orf32",
"FLJ40752"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 16 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 52: Non-specific - Mitochondria | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 11,604 | 8 |
ENSG00000166278 | C2 | Complement C2 | [
"P06681"
] | 6 | 31897785-31945673 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016775"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Complement pathway",
"Immunity",
"Innate immunity"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Age-related macular degeneration",
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | null | Supported | null | 7 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 20: Macrophages & Microglia - Immune response | Cluster 51: Myeloma - Immunoglobulins | Cluster 102: Non-specific - Mixed function | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 6 | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 11,605 | 7 |
ENSG00000166289 | PLEKHF1 | Pleckstrin homology and FYVE domain containing 1 | [
"Q96S99"
] | 19 | 29665459-29675477 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA025925"
] | [
"APPD",
"MGC4090",
"PHAFIN1",
"ZFYVE15"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Apoptosis"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 4 | null | null | Cluster 1: T-cells - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 24: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 11,606 | 3 |
ENSG00000166292 | TMEM100 | Transmembrane protein 100 | [
"Q9NV29"
] | 17 | 55719627-55732121 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA055936"
] | [
"FLJ10970",
"FLJ37856"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Differentiation"
] | [
"Developmental protein"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Uncertain | Approved | null | 32 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 5: Rhabdoid - Unknown function | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 13: Lung - Secretion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 11,607 | 1 |
ENSG00000166295 | ANAPC16 | Anaphase promoting complex subunit 16 | [
"Q96DE5"
] | 10 | 72216000-72235860 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037815"
] | [
"APC16",
"bA570G20.3",
"C10orf104",
"CENP-27",
"FLJ33728"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Ubl conjugation pathway"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 79 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 54: Immune cells - T cell receptor | Cluster 52: Non-specific - Mitochondria | Cluster 15: Non-specific - Protein processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 11,608 | 6 |
ENSG00000166311 | SMPD1 | Sphingomyelin phosphodiesterase 1 | [
"P17405"
] | 11 | 6390440-6394998 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"ASM"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Host-virus interaction",
"Lipid metabolism"
] | [
"Glycosidase",
"Hydrolase"
] | [
"Disease variant",
"Neurodegeneration",
"Niemann-Pick disease"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | null | null | 1 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 45: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 11,609 | 7 |
ENSG00000166313 | APBB1 | Amyloid beta precursor protein binding family B member 1 | [
"O00213"
] | 11 | 6395125-6419414 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038521",
"HPA038522"
] | [
"Fe65",
"RIR"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"DNA damage",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator",
"Repressor"
] | [] | [
"Plasma membrane"
] | [
"Endoplasmic reticulum"
] | [] | [] | Supported | Approved | null | 32 | null | null | Cluster 39: T-cells - T-cell receptor | Cluster 30: White matter - Myelination | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 80: Oligodendrocytes - Myelination | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 11,610 | 6 |
ENSG00000166317 | SYNPO2L | Synaptopodin 2 like | [
"Q9H987"
] | 10 | 73644881-73663803 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055192",
"HPA057142"
] | [
"FLJ12921"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 33: Sarcoma - Muscle contraction | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 41: Striated muscle - Muscle contraction | Group enriched | Detected in some | 17 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,611 | 4 |
ENSG00000166321 | NUDT13 | Nudix hydrolase 13 | [
"Q86X67"
] | 10 | 73110375-73131828 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA040636"
] | [
"DKFZp586P2219"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | No | Cluster 23: B-cells - Immunoglobulins | Cluster 15: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 11,612 | 6 |
ENSG00000166323 | C11orf65 | Chromosome 11 open reading frame 65 | [
"Q8NCR3"
] | 11 | 108308519-108467531 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"MFI",
"MGC33948"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 8 | null | null | Cluster 32: Basophils - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 18 | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 11,613 | 8 |
ENSG00000166329 | CCDC182 | Coiled-coil domain containing 182 | [
"A6NF36"
] | 17 | 57744495-57745299 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA023446"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | null | Cluster 55: Lymphoma - Immune response | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in single | 202 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 96 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,615 | 8 |
ENSG00000166333 | ILK | Integrin linked kinase | [
"Q13418"
] | 11 | 6603708-6610874 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004041",
"HPA048437"
] | [] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Focal adhesion sites"
] | [
"Nucleoplasm",
"Actin filaments",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 96 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 8: Immune cells - Immune response | Cluster 24: Non-specific - Unknown function | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 11,616 | 1 |
ENSG00000166340 | TPP1 | Tripeptidyl peptidase 1 | [
"O14773"
] | 11 | 6612768-6619448 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037709",
"HPA044868"
] | [
"CLN2",
"LPIC",
"SCAR7",
"TPP-1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Disease variant",
"Epilepsy",
"Neurodegeneration",
"Neuronal ceroid lipofuscinosis",
"Spinocerebellar ataxia"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Enhanced | null | 20 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 21: Non-specific - Metabolism | Cluster 44: Connective tissue cells - ECM organization | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 11,618 | 3 |
ENSG00000166341 | DCHS1 | Dachsous cadherin-related 1 | [
"Q96JQ0"
] | 11 | 6621330-6655809 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017970",
"HPA050246"
] | [
"CDH25",
"CDHR6",
"FIB1",
"FLJ11790",
"KIAA1773",
"PCDH16"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [
"Deafness",
"Disease variant",
"Intellectual disability"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 11,619 | 2 |
ENSG00000166342 | NETO1 | Neuropilin and tolloid like 1 | [
"Q8TDF5"
] | 18 | 72742314-72868146 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA064630"
] | [
"BCTL1",
"BTCL1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [] | [
"Receptor"
] | [] | [
"Golgi apparatus"
] | [] | [
"Secreted in brain"
] | [
"Receptor"
] | Approved | null | null | null | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in some | 12 | Cancer enriched | Detected in many | 7 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 11,620 | 2 |
ENSG00000166343 | MSS51 | MSS51 mitochondrial translational activator | [
"Q4VC12"
] | 10 | 73423579-73433561 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038564"
] | [
"FLJ39565",
"ZMYND17"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Uncertain | null | null | 19 | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 56: Non-specific - Sensory perception | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enriched | Detected in many | 5 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in single | null | Cell type enriched | Detected in many | 7 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 11,621 | 9 |
ENSG00000166347 | CYB5A | Cytochrome b5 type A | [
"P00167"
] | 18 | 74250846-74291973 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB006333",
"HPA047548",
"HPA058547"
] | [
"CYB5"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Electron transport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Enhanced | Enhanced | null | 26 | No | No | Cluster 34: B-cells - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 11,622 | 6 |
ENSG00000166348 | USP54 | Ubiquitin specific peptidase 54 | [
"Q70EL1"
] | 10 | 73497538-73626117 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047663",
"HPA063665"
] | [
"bA137L10.3",
"bA137L10.4",
"C10orf29",
"FLJ37318"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 31 | null | null | Cluster 16: Non-specific - Cell proliferation | Cluster 11: White matter - Signal transduction | Cluster 60: Prostate cancer - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Lung Adenocarcinoma"
] | 11,623 | 3 |
ENSG00000166349 | RAG1 | Recombination activating 1 | [
"P15918"
] | 11 | 36510372-36593156 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043939",
"HPA073731"
] | [
"MGC43321",
"RNF74"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"DNA recombination",
"Ubl conjugation pathway"
] | [
"Chromatin regulator",
"DNA-binding",
"Endonuclease",
"Hydrolase",
"Multifunctional enzyme",
"Nuclease",
"Transferase"
] | [
"Disease variant",
"SCID"
] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Approved | null | null | 12 | null | null | null | null | Cluster 6: Leukemia - Signal transduction | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 80: Thymus - Adaptive immune response | Tissue enriched | Detected in some | 90 | Group enriched | Detected in some | 6 | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 11,624 | 8 |
ENSG00000166351 | POTED | POTE ankyrin domain family member D | [
"Q86YR6"
] | 21 | 13609777-13645823 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"A26B3",
"ANKRD21",
"CT104.1",
"POTE",
"POTE-21",
"POTE21"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 47: Testis - Mixed function | Tissue enriched | Detected in single | 11 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,625 | 6 |
ENSG00000166352 | IFTAP | Intraflagellar transport associated protein | [
"Q86VG3"
] | 11 | 36594369-36675695 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044880"
] | [
"C11orf74",
"FLJ38678",
"HEPIS",
"NWC"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [
"Aggresome"
] | [] | [] | Approved | Uncertain | null | 3 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 23: Choroid plexus - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 11,626 | 1 |
ENSG00000166359 | WDR88 | WD repeat domain 88 | [
"Q6ZMY6"
] | 19 | 33132090-33175799 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041916",
"HPA050336"
] | [
"PQWD"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 4: Non-specific - Transcription | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 47: Testis - Mixed function | Tissue enriched | Detected in some | 6 | Low cancer specificity | Detected in many | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,627 | 3 |
ENSG00000166368 | OR2D2 | Olfactory receptor family 2 subfamily D member 2 | [
"Q9H210"
] | 11 | 6891574-6892500 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [] | [
"hg27",
"OR11-610",
"OR2D1"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [
"Olfaction",
"Sensory transduction"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 32: Cerebral cortex - Mixed function | Cluster 54: Non-specific - Transcription | null | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,629 | 5 |
ENSG00000166377 | ATP9B | ATPase phospholipid transporting 9B (putative) | [
"O43861"
] | 18 | 79069285-79378287 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA029364"
] | [
"ATPIIB"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | Cluster 20: Non-specific - DNA binding | Cluster 9: Non-specific - Receptor signaling | Cluster 56: Non-specific - Sensory perception | Cluster 7: Non-specific - Transcription | Cluster 40: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 11,630 | 4 |
ENSG00000166387 | PPFIBP2 | PPFIA binding protein 2 | [
"Q8ND30"
] | 11 | 7513298-7657127 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001935",
"HPA003911"
] | [
"Cclp1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 7 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 55: Lymphoma - Immune response | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 11,631 | 4 |
ENSG00000166391 | MOGAT2 | Monoacylglycerol O-acyltransferase 2 | [
"Q3SYC2"
] | 11 | 75717838-75732958 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028834"
] | [
"DGAT2L5",
"FLJ22644",
"MGAT2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Glycerol metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 19 | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 11,632 | 1 |
ENSG00000166394 | CYB5R2 | Cytochrome b5 reductase 2 | [
"Q6BCY4"
] | 11 | 7665100-7677222 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038962",
"HPA061707"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis",
"Steroid metabolism",
"Sterol biosynthesis",
"Sterol metabolism"
] | [
"Oxidoreductase"
] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 6 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 11: White matter - Signal transduction | Cluster 55: Lymphoma - Immune response | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 47: Testis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 7 | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme"
] | 11,633 | 1 |
ENSG00000166396 | SERPINB7 | Serpin family B member 7 | [
"O75635"
] | 18 | 63752935-63805376 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024200"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [
"Palmoplantar keratoderma"
] | [
"Endoplasmic reticulum"
] | [
"Mitochondria"
] | [] | [] | Approved | Enhanced | null | 23 | null | null | null | null | Cluster 72: Neuronal - Signal transduction | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 37: Skin - Keratinization | Group enriched | Detected in some | 6 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 11,634 | 1 |
ENSG00000166398 | GARRE1 | Granule associated Rac and RHOG effector 1 | [
"O15063"
] | 19 | 34254552-34355566 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014570"
] | [
"KIAA0355"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 12 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 6: Non-specific - Immune response | Cluster 4: Non-specific - Transcription | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 11,635 | 6 |
ENSG00000166401 | SERPINB8 | Serpin family B member 8 | [
"P50452"
] | 18 | 63970029-64019779 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034300",
"HPA070605"
] | [
"CAP2",
"PI8"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [
"Golgi apparatus",
"Actin filaments"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 11 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 49: Hindbrain - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 11,636 | 9 |
ENSG00000166402 | TUB | TUB bipartite transcription factor | [
"P50607"
] | 11 | 8019244-8106243 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017997",
"HPA049019"
] | [
"rd5"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Phagocytosis",
"Sensory transduction"
] | [] | [
"Obesity"
] | [
"Centriolar satellite",
"Basal body"
] | [
"Vesicles",
"Plasma membrane"
] | [
"Intracellular and membrane"
] | [
"Other"
] | Approved | Uncertain | null | 1 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 11,637 | 4 |
ENSG00000166405 | RIC3 | RIC3 acetylcholine receptor chaperone | [
"Q7Z5B4"
] | 11 | 8106056-8169055 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA065016"
] | [
"AYST720",
"FLJ11608",
"PRO1385"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Chaperone"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Other"
] | null | Approved | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 11,638 | 2 |
ENSG00000166407 | LMO1 | LIM domain only 1 | [
"P25800"
] | 11 | 8224309-8268716 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"RBTN1",
"RHOM1",
"TTG1"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes",
"Proto-oncogene"
] | [] | [] | [] | [] | null | null | null | 100 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 1: Neuronal - Visual perception | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in many | 4 | Cancer enriched | Detected in many | 6 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,639 | 5 |
ENSG00000166411 | IDH3A | Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha | [
"P50213"
] | 15 | 78131498-78171945 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041465",
"HPA062971"
] | [] | [
"Citric acid cycle related proteins",
"Disease related genes",
"Enzymes",
"Essential proteins",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Tricarboxylic acid cycle"
] | [
"Oxidoreductase"
] | [
"Disease variant",
"FDA approved drug targets",
"Retinitis pigmentosa"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Supported | null | 10 | No | No | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 23: Choroid plexus - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 11,640 | 4 |
ENSG00000166415 | WDR72 | WD repeat domain 72 | [
"Q3MJ13"
] | 15 | 53513741-53762878 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA048212",
"HPA057410",
"HPA059819"
] | [
"FLJ38736"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Biomineralization"
] | [] | [
"Amelogenesis imperfecta"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | null | null | Cluster 56: Non-specific - Sensory perception | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 11,641 | 6 |
ENSG00000166426 | CRABP1 | Cellular retinoic acid binding protein 1 | [
"P29762"
] | 15 | 78340353-78348225 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017203"
] | [
"CRABP",
"CRABP-I",
"CRABPI",
"RBP5"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transport"
] | [] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Enhanced | Supported | 3 | null | null | null | Cluster 45: Non-specific - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,642 | 5 |
ENSG00000166428 | PLD4 | Phospholipase D family member 4 | [
"Q96BZ4"
] | 14 | 104924713-104937761 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA051512"
] | [
"C14orf175"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Immunity",
"Inflammatory response",
"Innate immunity",
"Lipid metabolism",
"Phospholipid metabolism"
] | [
"Exonuclease",
"Hydrolase",
"Nuclease"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 5 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 43: Hindbrain - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 77 | Cancer enhanced | Detected in all | null | Cell type enriched | Detected in some | 4 | Immune cell enriched | Detected in many | 5 | 3 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma"
] | 11,643 | 6 |
ENSG00000166432 | ZMAT1 | Zinc finger matrin-type 1 | [
"Q5H9K5"
] | X | 101882288-101932031 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA012827"
] | [
"KIAA1789"
] | [
"Predicted intracellular proteins"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 3 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 11,644 | 7 |
ENSG00000166435 | XRRA1 | X-ray radiation resistance associated 1 | [
"Q6P2D8"
] | 11 | 74807739-74949200 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA039263"
] | [
"FLJ00225"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | null | null | null | null | null | Cluster 32: Basophils - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 11,645 | 7 |
ENSG00000166436 | TRIM66 | Tripartite motif containing 66 | [] | 11 | 8612037-8682694 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA027420"
] | [
"C11orf29",
"KIAA0298",
"TIF1D"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | null | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 56: Non-specific - Sensory perception | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 11,646 | 5 |
ENSG00000166439 | RNF169 | Ring finger protein 169 | [
"Q8NCN4"
] | 11 | 74748849-74842413 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038505",
"HPA046138",
"HPA047952"
] | [
"KIAA1991"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Nucleoli",
"Nucleoli rim",
"Cytosol"
] | [] | [] | Enhanced | Uncertain | null | 16 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 46: Brainstem - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 11,647 | 7 |
ENSG00000166444 | DENND2B | DENN domain containing 2B | [
"P78524"
] | 11 | 8693351-8910951 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046796"
] | [
"HTS1",
"p126",
"ST5"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 10 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 19: Astrocytes - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 4 | 0 | 0 | 0 | [] | [] | [] | 11,649 | 9 |
ENSG00000166446 | CDYL2 | Chromodomain Y like 2 | [
"Q8N8U2"
] | 16 | 80597907-80804598 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041016"
] | [
"FLJ38866"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 10 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 60: Prostate cancer - Unknown function | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 11,650 | 3 |
ENSG00000166448 | TMEM130 | Transmembrane protein 130 | [
"Q8N3G9"
] | 7 | 98846488-98870771 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012928"
] | [
"DKFZp761L1417",
"FLJ42643"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Uncertain | null | 10 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 64: Connective tissue cells - ECM organization | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | 11,651 | 7 |
ENSG00000166451 | CENPN | Centromere protein N | [
"Q96H22"
] | 16 | 81006552-81033114 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052870"
] | [
"BM039",
"C16orf60",
"FLJ13607",
"FLJ22660"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 9 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 11: White matter - Signal transduction | Cluster 68: Non-specific - Cell cycle regulation | Cluster 27: Non-specific - Cell proliferation | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 11,653 | 6 |
ENSG00000166452 | AKIP1 | A-kinase interacting protein 1 | [
"Q9NQ31"
] | 11 | 8911139-8920084 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061391"
] | [
"BCA3",
"C11orf17"
] | [
"Predicted intracellular proteins"
] | [] | [] | [
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 12 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 46: Brainstem - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 97: Non-specific - Cellular respiration | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 11,654 | 5 |
ENSG00000166454 | ATMIN | ATM interactor | [
"O43313"
] | 16 | 81035842-81047350 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054967",
"HPA066900"
] | [
"ASCIZ",
"KIAA0431",
"ZNF822"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nuclear bodies"
] | [] | [] | [] | Supported | Approved | null | 11 | null | null | Cluster 24: Non-specific - Transcription | Cluster 1: Neurons - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 10: Brain - Synaptic signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 11,655 | 4 |
ENSG00000166455 | C16orf46 | Chromosome 16 open reading frame 46 | [
"Q6P387"
] | 16 | 81053497-81077267 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA041136",
"HPA041379"
] | [
"FLJ32702"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | null | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 68: Non-specific - Cell cycle regulation | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 11,656 | 8 |
ENSG00000166479 | TMX3 | Thioredoxin related transmembrane protein 3 | [
"Q96JJ7"
] | 18 | 68673688-68715108 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA014157"
] | [
"FLJ20793",
"KIAA1830",
"PDIA13",
"TXNDC10"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Isomerase"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Uncertain | null | 14 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 13: Non-specific - Mixed function | Cluster 7: Non-specific - Transcription | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 11,661 | 4 |
ENSG00000166482 | MFAP4 | Microfibril associated protein 4 | [
"P55083"
] | 17 | 19383442-19387190 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054097"
] | [] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Cell adhesion"
] | Approved | Supported | null | 74 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 11 | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 11,662 | 4 |
ENSG00000166483 | WEE1 | WEE1 G2 checkpoint kinase | [
"P30291"
] | 11 | 9573670-9593457 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004619",
"HPA068845"
] | [
"WEE1A"
] | [
"Cancer-related genes",
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Cancer-related genes"
] | [
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 41 | No | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 44: Non-specific - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 11,663 | 8 |
ENSG00000166484 | MAPK7 | Mitogen-activated protein kinase 7 | [
"Q13164"
] | 17 | 19377721-19383544 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB018561",
"HPA031031"
] | [
"BMK1",
"ERK5",
"PRKM7"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Differentiation"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 39 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 11,664 | 5 |
ENSG00000166501 | PRKCB | Protein kinase C beta | [
"P05771"
] | 16 | 23835983-24220611 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003843",
"HPA048321",
"HPA054203"
] | [
"PKCB",
"PKCbeta",
"PRKCB1",
"PRKCB2"
] | [
"Cancer-related genes",
"Enzymes",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins",
"Transporters"
] | [
"Adaptive immunity",
"Apoptosis",
"Immunity",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 31 | null | null | Cluster 32: Basophils - Transcription | Cluster 53: Neurons - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 11,665 | 1 |
ENSG00000166503 | HDGFL3 | HDGF like 3 | [
"Q9Y3E1"
] | 15 | 83112738-83207823 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040719"
] | [
"Hdgfrp3",
"HRP-3"
] | [
"Predicted intracellular proteins"
] | [] | [
"Growth factor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 1 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 58: Non-specific - Nuclear processes | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 11,666 | 9 |
ENSG00000166507 | NDST2 | N-deacetylase and N-sulfotransferase 2 | [
"P52849"
] | 10 | 73801911-73811798 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051515"
] | [
"HSST2",
"NST2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Hydrolase",
"Multifunctional enzyme",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 15: Non-specific - Transcription | Cluster 49: HMC-1 - Innate immune response | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 11,667 | 6 |
ENSG00000166508 | MCM7 | Minichromosome maintenance complex component 7 | [
"P33993"
] | 7 | 100092728-100101940 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002163",
"HPA003898",
"CAB016312"
] | [
"CDC47",
"MCM2",
"PPP1R104"
] | [
"Cancer-related genes",
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"DNA replication"
] | [
"DNA-binding",
"Helicase",
"Hydrolase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Basal body",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 148 | null | Yes | Cluster 14: Non-specific - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 39: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 11,668 | 9 |
ENSG00000166509 | CLEC3A | C-type lectin domain family 3 member A | [
"O75596"
] | 16 | 78022515-78066761 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051511"
] | [
"CLECSF1"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | Uncertain | null | 8 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 14 | Cancer enriched | Detected in some | 126 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | 11,669 | 9 |
ENSG00000166523 | CLEC4E | C-type lectin domain family 4 member E | [
"Q9ULY5"
] | 12 | 8533305-8540905 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004935"
] | [
"CLECSF9",
"MINCLE"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Immunity",
"Innate immunity"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 101 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 9: Non-specific - Receptor signaling | Cluster 15: Kidney cancer - Membrane components | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 7 | Group enriched | Detected in some | 16 | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 11,671 | 1 |
ENSG00000166526 | ZNF3 | Zinc finger protein 3 | [
"P17036"
] | 7 | 100064033-100082548 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003719"
] | [
"A8-51",
"FLJ20216",
"HF.12",
"KOX25",
"PP838",
"Zfp113"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Supported | Supported | 14 | No | No | Cluster 32: Basophils - Transcription | Cluster 26: Oligodendrocytes - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Skin Cutaneous Melanoma"
] | 11,672 | 3 |
ENSG00000166527 | CLEC4D | C-type lectin domain family 4 member D | [
"Q8WXI8"
] | 12 | 8509475-8522366 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA004906"
] | [
"CD368",
"CLECSF8",
"Dectin-3",
"MCL",
"Mpcl"
] | [
"CD markers",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Immunity",
"Innate immunity"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 54 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | null | Cluster 71: Lymphoma - Inflammatory response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in some | 9 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 63 | Group enriched | Detected in some | 6 | Group enriched | Detected in many | 17 | 0 | 0 | 0 | [] | [] | [] | 11,673 | 5 |
ENSG00000166529 | ZSCAN21 | Zinc finger and SCAN domain containing 21 | [
"Q9Y5A6"
] | 7 | 100049774-100065040 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016948",
"HPA023591"
] | [
"DKFZp434L134",
"NY-REN-21",
"Zipro1",
"ZNF38"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Meiosis",
"Spermatogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Uncertain | null | 41 | null | null | Cluster 32: Basophils - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 11: Muller glia cells - Retinal homeostasis | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Thyroid Carcinoma"
] | 11,674 | 7 |
ENSG00000166532 | RIMKLB | Ribosomal modification protein rimK like family member B | [
"Q9ULI2"
] | 12 | 8681600-8783095 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA059552"
] | [
"FAM80B",
"KIAA1238",
"NAAGS",
"NAAGS-I"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Ligase"
] | [] | [
"Nucleoplasm",
"Centriolar satellite"
] | [] | [] | [] | Approved | null | null | null | null | null | Cluster 32: Basophils - Transcription | Cluster 44: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 11,675 | 3 |
ENSG00000166535 | A2ML1 | Alpha-2-macroglobulin like 1 | [
"A8K2U0"
] | 12 | 8822621-8887001 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038847",
"HPA038848"
] | [
"CPAMD9",
"FLJ25179",
"p170"
] | [
"Disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Enzyme inhibitor"
] | null | Enhanced | null | 33 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 11,676 | 3 |
ENSG00000166546 | BEAN1 | Brain expressed associated with NEDD4 1 | [
"Q3B7T3"
] | 16 | 66427295-66493529 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA053851"
] | [
"SCA31"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Neurodegeneration",
"Spinocerebellar ataxia"
] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Uncertain | Uncertain | null | null | null | null | null | Cluster 24: Neurons - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,677 | 1 |
ENSG00000166548 | TK2 | Thymidine kinase 2 | [
"O00142"
] | 16 | 66508003-66552544 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041162"
] | [
"SCA31"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA synthesis"
] | [
"Kinase",
"Transferase"
] | [
"Disease variant",
"FDA approved drug targets",
"Primary mitochondrial disease",
"Progressive external ophthalmoplegia"
] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 19: Astrocytes - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 11,678 | 3 |
ENSG00000166557 | TMED3 | Transmembrane p24 trafficking protein 3 | [
"Q9Y3Q3"
] | 15 | 79311112-79427432 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049314",
"HPA076949"
] | [
"C15orf22",
"p24B",
"p24g4",
"p24gamma4"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Enhanced | null | 13 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 44: Non-specific - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 82: Salivary gland - Secretion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 11,679 | 5 |
ENSG00000166558 | SLC38A8 | Solute carrier family 38 member 8 | [
"A6NNN8"
] | 16 | 84009667-84042795 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Amino-acid transport",
"Transport"
] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 41: Oocytes - Oogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in single | null | Cancer enhanced | Detected in single | null | Group enriched | Detected in some | 8 | Cell type enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,680 | 9 |
ENSG00000166562 | SEC11C | SEC11 homolog C, signal peptidase complex subunit | [
"Q9BY50"
] | 18 | 59139866-59158832 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026816",
"HPA047533"
] | [
"SEC11L3",
"SPC21",
"SPCS4C"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Hydrolase",
"Protease"
] | [] | [
"Nuclear membrane"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Approved | null | 25 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 27: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 11,681 | 5 |
ENSG00000166569 | CPLX4 | Complexin 4 | [
"Q7Z7G2"
] | 18 | 59275156-59318649 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047627"
] | [
"CPX-IV"
] | [
"Predicted intracellular proteins"
] | [
"Exocytosis",
"Neurotransmitter transport",
"Sensory transduction",
"Transport",
"Vision"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 85 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 1: Neuronal - Visual perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 90 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 14 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,682 | 5 |
ENSG00000166573 | GALR1 | Galanin receptor 1 | [
"P47211"
] | 18 | 77249848-77277900 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA074584"
] | [
"GALNR",
"GALNR1"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Supported | null | null | null | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 66: Non-specific - Mitochondria | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in single | 5 | Group enriched | Detected in some | 8 | Cell type enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,683 | 6 |
ENSG00000166575 | TMEM135 | Transmembrane protein 135 | [
"Q86UB9"
] | 11 | 87037844-87328824 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA056685",
"HPA069473"
] | [
"FLJ22104"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Uncertain | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 89: Adipocytes - Lipid metabolism | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 11,684 | 6 |
ENSG00000166578 | IQCD | IQ motif containing D | [
"Q96DY2"
] | 12 | 113195441-113221094 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046810"
] | [
"CFAP84",
"DRC10"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | [] | Approved | Supported | null | null | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 3: Choroid plexus - Cilium | Cluster 46: Lymphoma - Humoral immune response | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 11,685 | 5 |
ENSG00000166579 | NDEL1 | NudE neurodevelopment protein 1 like 1 | [
"Q9GZM8"
] | 17 | 8413131-8490411 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017916"
] | [
"MITAP1",
"NDE1L1",
"NDE2",
"NUDEL"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis",
"Transport"
] | [
"Developmental protein"
] | [] | [] | [] | [] | [] | null | Approved | null | 111 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 14: Neurons - Synaptic function | Cluster 42: Non-specific - Unknown function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 15: Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 11,686 | 2 |
ENSG00000166582 | CENPV | Centromere protein V | [
"Q7Z7K6"
] | 17 | 16342534-16353656 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042529",
"HPA042616"
] | [
"CENP-V",
"p30",
"PRR6"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear membrane",
"Nucleoli",
"Cytokinetic bridge",
"Midbody",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 25 | Yes | No | Cluster 22: Eosinophils - Transcription | Cluster 32: Cerebral cortex - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 11,687 | 4 |
ENSG00000166589 | CDH16 | Cadherin 16 | [
"O75309"
] | 16 | 66908122-66918917 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013526",
"HPA036260"
] | [] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | null | null | Cluster 15: Kidney cancer - Membrane components | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in some | 8 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 11,688 | 1 |
ENSG00000166592 | RRAD | RRAD, Ras related glycolysis inhibitor and calcium channel regulator | [
"P55042"
] | 16 | 66921679-66925536 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041755"
] | [
"RAD",
"REM3"
] | [
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding"
] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Golgi apparatus",
"Flagellar centriole"
] | [] | [] | Approved | Uncertain | null | 8 | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 15: Kidney cancer - Membrane components | Cluster 78: Plasma cells - Antibody production & ER-stress response | Cluster 25: Non-specific - Basic cellular processes | Group enriched | Detected in all | 5 | Cancer enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,689 | 6 |
ENSG00000166596 | CFAP52 | Cilia and flagella associated protein 52 | [
"Q8N1V2"
] | 17 | 9576627-9643447 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023247"
] | [
"FLJ37528",
"WDR16",
"WDRPUH"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Heterotaxy"
] | [
"Microtubules"
] | [
"Primary cilium",
"Centriolar satellite",
"Basal body"
] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 5: Rhabdoid - Unknown function | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,691 | 9 |
ENSG00000166598 | HSP90B1 | Heat shock protein 90 beta family member 1 | [
"P14625"
] | 12 | 103930107-103953931 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003901",
"CAB005224",
"HPA008424",
"CAB078151"
] | [
"GP96",
"GRP94",
"TRA1"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Chaperone",
"Hydrolase"
] | [
"Cancer-related genes"
] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Enhanced | Enhanced | null | 115 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 11,692 | 7 |
ENSG00000166603 | MC4R | Melanocortin 4 receptor | [
"P32245"
] | 18 | 60371062-60372775 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016719"
] | [] | [
"Disease related genes",
"FDA approved drug targets",
"G-protein coupled receptors",
"Human disease related genes",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Disease variant",
"FDA approved drug targets",
"Obesity"
] | [] | [] | [] | [] | null | Uncertain | null | 2 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 109: Neurons - Neuronal signaling | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in some | 9 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,693 | 9 |
ENSG00000166619 | BLCAP | BLCAP apoptosis inducing factor | [
"P62952"
] | 20 | 37492472-37527931 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047390"
] | [
"BC10"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Cell cycle"
] | [] | [
"Tumor suppressor"
] | [
"Nucleoli"
] | [] | [] | [] | Approved | null | null | 14 | null | null | Cluster 32: Basophils - Transcription | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 11,694 | 6 |
ENSG00000166634 | SERPINB12 | Serpin family B member 12 | [
"Q96P63"
] | 18 | 63542369-63569329 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Protease inhibitor",
"Serine protease inhibitor"
] | [] | [] | [] | [] | [] | null | null | null | 5 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 65: Non-specific - Unknown function | Cluster 26: Keratinocytes - Keratinization | Cluster 58: Skin - Keratinization | Group enriched | Detected in some | 4 | Group enriched | Detected in some | 14 | Group enriched | Detected in some | 11 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 11,695 | 1 |
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