ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000171503
ETFDH
Electron transfer flavoprotein dehydrogenase
[ "Q16134" ]
4
158671968-158710742
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041978", "HPA058140" ]
[ "ETFQO" ]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Electron transport", "Transport" ]
[ "Oxidoreductase" ]
[ "Disease variant", "FDA approved drug targets", "Glutaricaciduria" ]
[ "Mitochondria" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Supported
Enhanced
null
5
null
null
Cluster 25: Non-specific - Unknown function
Cluster 42: Choroid plexus - Mitochondria
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 55: Myocytes - Oxidative muscle function
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
12,817
8
ENSG00000171505
OR1N1
Olfactory receptor family 1 subfamily N member 1
[ "Q8NGS0" ]
9
122526358-122527296
Evidence at transcript level
Evidence at transcript level
No human protein/transcript evidence
No human protein/transcript evidence
[]
[ "OR1-26", "OR1N3" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
null
Not detected
Not detected
null
Not detected
Not detected
null
Cancer enriched
Detected in single
5
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,818
1
ENSG00000171509
RXFP1
Relaxin family peptide receptor 1
[ "Q9HBX9" ]
4
158315311-158653372
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027067" ]
[ "LGR7", "RXFPR1" ]
[ "G-protein coupled receptors", "Predicted membrane proteins", "Transporters" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Group enriched
Detected in some
6
Cancer enriched
Detected in some
5
Group enriched
Detected in many
7
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
12,819
5
ENSG00000171517
LPAR3
Lysophosphatidic acid receptor 3
[ "Q9UBY5" ]
1
84811602-84893206
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA013421" ]
[ "Edg-7", "EDG7", "HOFNH30", "LP-A3", "LPA3", "RP4-678I3" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[ "Plasma membrane" ]
[ "Primary cilium" ]
[]
[]
Supported
null
null
46
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Bladder Urothelial Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
12,820
5
ENSG00000171530
TBCA
Tubulin folding cofactor A
[ "O75347" ]
5
77691166-77868780
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036487" ]
[]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "Chaperone" ]
[]
[ "Microtubules" ]
[ "Nucleoli" ]
[]
[]
Supported
Approved
null
9
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 97: Non-specific - Cellular respiration
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
5
0
5
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,822
8
ENSG00000171533
MAP6
Microtubule associated protein 6
[ "Q96JE9" ]
11
75586918-75669038
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB015442", "CAB022600", "HPA039061", "HPA039062" ]
[ "FLJ41346", "KIAA1878", "MAP6-N", "STOP" ]
[ "Predicted intracellular proteins" ]
[ "Transport" ]
[ "Calmodulin-binding" ]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
Cluster 24: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Pancreatic Adenocarcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,824
3
ENSG00000171540
OTP
Orthopedia homeobox
[ "Q5XKR4" ]
5
77628712-77638713
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059342" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli fibrillar center", "Nuclear bodies" ]
[]
[]
Approved
Enhanced
Supported
5
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 59: Leukemia - T-cell receptor
Cluster 109: Neurons - Neuronal signaling
Cluster 36: Brain & Liver - Signaling
Tissue enriched
Detected in single
70
Group enriched
Detected in some
21
Cancer enhanced
Detected in single
null
Group enriched
Detected in some
12
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
12,825
4
ENSG00000171551
ECEL1
Endothelin converting enzyme like 1
[ "O95672" ]
2
232479827-232487834
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA067560", "HPA069756", "HPA077424" ]
[ "DINE", "XCE" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Nuclear membrane", "Nucleoli" ]
[]
[]
Uncertain
Approved
Supported
54
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 65: Non-specific - Unknown function
Cluster 11: Muller glia cells - Retinal homeostasis
Cluster 75: Ovary - Mixed function
Group enriched
Detected in many
6
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
4
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,826
2
ENSG00000171552
BCL2L1
BCL2 like 1
[ "Q07817" ]
20
31664452-31723989
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035734", "CAB072801" ]
[ "Bcl-X", "bcl-xL", "bcl-xS", "BCL2L", "BCLX", "PPP1R52" ]
[ "Cancer-related genes", "Essential proteins", "Predicted membrane proteins", "RAS pathway related proteins", "Transporters" ]
[ "Apoptosis", "Endocytosis" ]
[]
[ "Cancer-related genes" ]
[ "Mitochondria" ]
[ "Nucleoli fibrillar center", "Acrosome" ]
[]
[]
Approved
Approved
null
83
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 42: Choroid plexus - Mitochondria
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,827
1
ENSG00000171557
FGG
Fibrinogen gamma chain
[ "P02679" ]
4
154604134-154612967
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011159", "HPA027529", "CAB033120", "HPA074638" ]
[]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Blood coagulation", "Hemostasis" ]
[]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets" ]
[ "Endoplasmic reticulum" ]
[ "Vesicles" ]
[ "Secreted to blood" ]
[ "Blood coagulation" ]
Approved
Supported
null
6
null
null
null
null
Cluster 71: Lymphoma - Inflammatory response
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in many
327
Cancer enriched
Detected in many
6
Cancer enriched
Detected in many
9
Cell type enriched
Detected in some
13
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,828
1
ENSG00000171560
FGA
Fibrinogen alpha chain
[ "P02671" ]
4
154583126-154590742
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB016776", "HPA051370", "HPA064755" ]
[]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted secreted proteins" ]
[ "Adaptive immunity", "Blood coagulation", "Hemostasis", "Immunity", "Innate immunity" ]
[]
[ "Amyloidosis", "Cancer-related genes", "Disease variant", "FDA approved drug targets" ]
[ "Endoplasmic reticulum" ]
[]
[ "Secreted to blood" ]
[ "Blood coagulation" ]
Enhanced
Supported
null
15
null
null
null
null
Cluster 18: Liver cancer - Metabolism
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in some
384
Cancer enriched
Detected in some
6
Cancer enriched
Detected in many
21
Cell type enriched
Detected in some
44
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,829
6
ENSG00000171561
OR2AT4
Olfactory receptor family 2 subfamily AT member 4
[ "A6NND4" ]
11
75081753-75096876
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 9: Non-specific - Receptor signaling
Cluster 56: Non-specific - Sensory perception
null
Cluster 40: Non-specific - Mixed function
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in single
null
Low cancer specificity
Detected in single
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,830
6
ENSG00000171564
FGB
Fibrinogen beta chain
[ "P02675" ]
4
154563011-154572807
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001900", "HPA001901", "CAB008624" ]
[]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Adaptive immunity", "Blood coagulation", "Hemostasis", "Immunity", "Innate immunity" ]
[]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets" ]
[ "Endoplasmic reticulum" ]
[]
[ "Secreted to blood" ]
[ "Blood coagulation" ]
Enhanced
Enhanced
null
24
null
null
null
null
Cluster 18: Liver cancer - Metabolism
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in some
351
Cancer enriched
Detected in many
8
Cancer enriched
Detected in many
21
Cell type enriched
Detected in some
76
Not detected in immune cells
Not detected
null
2
0
2
[ "Liver Hepatocellular Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
12,831
2
ENSG00000171566
PLRG1
Pleiotropic regulator 1
[ "O43660" ]
4
154535005-154550400
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035931", "HPA035932", "HPA061486" ]
[ "Cwc1", "PRL1", "Prp46", "PRPF46", "TANGO4" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[]
[]
[ "Nucleoplasm", "Nuclear speckles" ]
[ "Nuclear membrane", "Nucleoli fibrillar center" ]
[]
[]
Supported
Supported
null
65
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 21: Non-specific - Metabolism
Cluster 13: Non-specific - Mixed function
Cluster 17: Non-specific - RNA processing
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
12,832
4
ENSG00000171574
ZNF584
Zinc finger protein 584
[ "Q8IVC4" ]
19
58401504-58431736
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA043408", "HPA048075" ]
[ "FLJ39899" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 30: Non-specific - DNA binding
Cluster 32: Cerebral cortex - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,833
6
ENSG00000171587
DSCAM
DS cell adhesion molecule
[ "O60469" ]
21
40010999-40847158
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019324", "HPA057493" ]
[ "CHD2-42", "CHD2-52" ]
[ "Plasma proteins", "Predicted membrane proteins" ]
[ "Cell adhesion", "Neurogenesis" ]
[]
[]
[ "Golgi apparatus" ]
[ "Cytosol" ]
[ "Intracellular and membrane" ]
[ "Cell adhesion" ]
Approved
Enhanced
null
3
null
null
null
Cluster 14: Neurons - Synaptic function
Cluster 27: Breast cancer - Unknown function
Cluster 14: Oligodendrocyte progenitor cells - Development & myelination
Cluster 73: Brain - Neuronal signaling
Group enriched
Detected in some
6
Low cancer specificity
Detected in single
null
Cancer enriched
Detected in single
15
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,834
4
ENSG00000171596
NMUR1
Neuromedin U receptor 1
[ "Q9HB89" ]
2
231523187-231530445
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at transcript level
[ "HPA027895" ]
[ "FM-3", "GPC-R", "GPR66", "NMU1R" ]
[ "G-protein coupled receptors", "Predicted membrane proteins", "Transporters" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Approved
null
1
null
null
Cluster 15: NK-cells - Unknown function
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 42: Retina - Visual perception
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in single
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
7
0
0
0
[]
[]
[]
12,836
8
ENSG00000171603
CLSTN1
Calsyntenin 1
[ "O94985" ]
1
9728926-9823984
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012412", "HPA077705" ]
[ "CDHR12", "CSTN1", "KIAA0911" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[ "Cancer-related genes" ]
[]
[]
[]
[]
null
Enhanced
null
8
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 14: Neurons - Synaptic function
Cluster 37: Non-specific - mRNA processing
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 27: Cerebellum - Synaptic function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,837
9
ENSG00000171604
CXXC5
CXXC finger protein 5
[ "Q7LFL8" ]
5
139647299-139683882
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036508", "HPA058148" ]
[ "HSPC195", "RINF", "WID" ]
[ "Predicted intracellular proteins" ]
[ "Transcription" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
null
null
null
Cluster 14: Non-specific - Unknown function
Cluster 26: Oligodendrocytes - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
7
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
12,838
6
ENSG00000171606
ZNF274
Zinc finger protein 274
[ "Q96GC6" ]
19
58183029-58213562
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028880" ]
[ "ZKSCAN19", "ZSCAN51" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[ "Centrosome" ]
[]
[]
Approved
Uncertain
null
4
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 55: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
12,839
9
ENSG00000171608
PIK3CD
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
[ "O00329" ]
1
9629889-9729114
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB015420", "HPA044953" ]
[ "p110D" ]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[ "Adaptive immunity", "Chemotaxis", "Differentiation", "Immunity", "Inflammatory response", "Innate immunity", "Lipid metabolism" ]
[ "Kinase", "Transferase" ]
[ "Disease variant", "FDA approved drug targets" ]
[ "Vesicles" ]
[ "Microtubules", "Cytokinetic bridge", "Primary cilium", "Primary cilium tip", "Cytosol" ]
[]
[]
Approved
Enhanced
null
11
Yes
No
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 18: Non-specific - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,840
4
ENSG00000171611
PTCRA
Pre T cell antigen receptor alpha
[ "Q6ISU1" ]
6
42915989-42925838
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "PT-ALPHA", "PTA" ]
[ "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 6: Non-specific - Immune response
Cluster 59: Leukemia - T-cell receptor
Cluster 47: Platelets - Hemostasis
Cluster 80: Thymus - Adaptive immune response
Tissue enriched
Detected in some
46
Group enriched
Detected in some
14
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in some
17
Immune cell enriched
Detected in some
46
0
0
0
[]
[]
[]
12,841
9
ENSG00000171612
SLC25A33
Solute carrier family 25 member 33
[ "Q9BSK2" ]
1
9539465-9585173
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049982" ]
[ "BMSC-MCP", "MGC4399", "PNC1" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
11
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 11: Muller glia cells - Retinal homeostasis
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
12,842
6
ENSG00000171621
SPSB1
SplA/ryanodine receptor domain and SOCS box containing 1
[ "Q96BD6" ]
1
9292894-9369532
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "SSB-1" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[]
[]
[]
[]
null
null
null
32
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 11: White matter - Signal transduction
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 103: Non-specific - Basic cellular processes
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
0
2
[]
[ "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
12,844
5
ENSG00000171631
P2RY6
Pyrimidinergic receptor P2Y6
[ "Q15077" ]
11
73264498-73305103
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA074751" ]
[ "P2Y6" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Enhanced
null
19
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 51: Neurons - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 5: Spleen - Immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
12
1
2
0
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
12,845
9
ENSG00000171634
BPTF
Bromodomain PHD finger transcription factor
[ "Q12830" ]
17
67825503-67984378
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029069", "HPA048289" ]
[ "FAC1", "FALZ", "NURF301" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Chromatin regulator" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
31
null
null
Cluster 20: Non-specific - DNA binding
Cluster 16: Non-specific - Transcription
Cluster 27: Breast cancer - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
12,846
1
ENSG00000171643
S100Z
S100 calcium binding protein Z
[ "Q8WXG8" ]
5
76850001-76921650
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA051929" ]
[ "Gm625", "S100-zeta" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Centrosome", "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
11
null
null
Cluster 25: Non-specific - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in some
null
Group enriched
Detected in some
6
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
6
0
0
0
[]
[]
[]
12,847
3
ENSG00000171649
ZIK1
Zinc finger protein interacting with K protein 1
[ "Q3SY52" ]
19
57578456-57593890
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA059975" ]
[ "ZNF762" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Intermediate filaments" ]
[]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 22: Eosinophils - Transcription
Cluster 15: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,848
9
ENSG00000171657
GPR82
G protein-coupled receptor 82
[ "Q96P67" ]
X
41724181-41730130
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA035914" ]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 43: Hindbrain - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 34: Lymphoid tissue - Adaptive immune response
Group enriched
Detected in some
5
Not detected
Not detected
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
10
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
12,849
9
ENSG00000171659
GPR34
G protein-coupled receptor 34
[ "Q9UPC5" ]
X
41688973-41697275
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA010668", "CAB025490" ]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 41: Basophils - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in single
null
Group enriched
Detected in all
4
Group enriched
Detected in many
6
Group enriched
Detected in many
16
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
12,850
5
ENSG00000171680
PLEKHG5
Pleckstrin homology and RhoGEF domain containing G5
[ "O94827" ]
1
6467122-6520074
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049570" ]
[ "GEF720", "KIAA0720", "Syx", "Tech" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Charcot-Marie-Tooth disease", "Disease variant", "Neurodegeneration", "Neuropathy" ]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
3
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 2: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,851
2
ENSG00000171681
ATF7IP
Activating transcription factor 7 interacting protein
[ "Q6VMQ6" ]
12
14365676-14502931
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016578", "HPA023505" ]
[ "ATF7IP1", "FLJ10688", "p621" ]
[ "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Activator", "Repressor" ]
[]
[ "Nucleoplasm", "Nuclear bodies" ]
[]
[]
[]
Enhanced
Supported
null
17
null
null
Cluster 14: Non-specific - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 38: Non-specific - Transcription
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
12,852
2
ENSG00000171695
LKAAEAR1
LKAAEAR motif containing 1
[ "Q8TD35" ]
20
64083376-64084398
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA056463" ]
[ "C20orf201" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
null
null
null
Cluster 25: Non-specific - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 67: Testis - Mixed function
Tissue enriched
Detected in some
5
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
7
Group enriched
Detected in some
10
0
0
0
[]
[]
[]
12,853
3
ENSG00000171700
RGS19
Regulator of G protein signaling 19
[ "P49795" ]
20
64073181-64079988
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA056384", "HPA069984" ]
[ "GAIP", "RGSGAIP" ]
[ "Predicted intracellular proteins" ]
[ "Autophagy" ]
[ "Signal transduction inhibitor" ]
[]
[ "Cell Junctions" ]
[ "Nucleoli fibrillar center" ]
[]
[]
Supported
Enhanced
null
15
null
null
Cluster 25: Non-specific - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
12,854
9
ENSG00000171703
TCEA2
Transcription elongation factor A2
[ "Q15560" ]
20
64049836-64072347
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043836" ]
[ "TFIIS" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Centrosome", "Basal body" ]
[]
[]
Supported
Approved
null
95
null
null
Cluster 22: Eosinophils - Transcription
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 62: Non-specific - Plasma proteins
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 10: Brain - Synaptic signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
12,855
2
ENSG00000171714
ANO5
Anoctamin 5
[ "Q75V66" ]
11
21782659-22283567
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA058857" ]
[ "GDD1", "LGMD2L", "TMEM16E" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[]
[]
[ "Disease variant", "Limb-girdle muscular dystrophy", "Osteogenesis imperfecta" ]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 11: Neuronal - Sensory perception
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 62: Skeletal muscle - Muscle contraction
Group enriched
Detected in many
8
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in some
5
Group enriched
Detected in many
4
Not detected in immune cells
Not detected
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
12,857
1
ENSG00000171720
HDAC3
Histone deacetylase 3
[ "O15379" ]
5
141620876-141636849
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005583", "HPA052052", "CAB072336" ]
[ "HD3", "KDAC3", "RPD3", "RPD3-2" ]
[ "Enzymes", "Essential proteins", "FDA approved drug targets", "Predicted intracellular proteins" ]
[ "Biological rhythms", "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Hydrolase", "Repressor" ]
[ "FDA approved drug targets" ]
[ "Nucleoplasm" ]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
Supported
Supported
null
142
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 14: Neurons - Synaptic function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 7: Non-specific - Transcription
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,858
6
ENSG00000171722
SPATA46
Spermatogenesis associated 46
[ "Q5T0L3" ]
1
162373203-162376854
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C1orf111", "TEKT2BP2" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[]
[]
[]
[]
[]
[]
null
null
null
23
null
null
null
Cluster 14: Neurons - Synaptic function
Cluster 1: Neuronal - Visual perception
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in some
10
Low cancer specificity
Detected in some
null
Not detected
Not detected
null
Group enriched
Detected in some
52
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,859
9
ENSG00000171723
GPHN
Gephyrin
[ "Q9NQX3" ]
14
66507407-67181803
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003116", "CAB004419", "HPA024694" ]
[ "KIAA1385" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Molybdenum cofactor biosynthesis" ]
[ "Multifunctional enzyme", "Transferase" ]
[ "Cancer-related genes", "Disease variant" ]
[ "Vesicles" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
18
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 16: Non-specific - Transcription
Cluster 30: Non-specific - Gene expression regulation
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 36: Brain & Liver - Signaling
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
12,860
3
ENSG00000171724
VAT1L
Vesicle amine transport 1 like
[ "Q9HCJ6" ]
16
77788564-77980107
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044061", "CAB046032", "HPA061138" ]
[ "KIAA1576" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Oxidoreductase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
3
null
null
null
Cluster 44: Non-specific - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 101: Choroid plexus epithelial cells - Ion transport
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,861
8
ENSG00000171729
TMEM51
Transmembrane protein 51
[ "Q9NW97" ]
1
15152532-15220478
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014547", "HPA019441" ]
[ "C1orf72", "FLJ10199" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
48
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 60: Stomach - Digestion
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
12,862
1
ENSG00000171735
CAMTA1
Calmodulin binding transcription activator 1
[ "Q9Y6Y1" ]
1
6785454-7769706
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036342", "HPA036343" ]
[ "KIAA0833" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator" ]
[ "Cancer-related genes", "Intellectual disability" ]
[ "Cytosol" ]
[ "Nucleoli", "Basal body" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 41: Basophils - Unknown function
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 37: Non-specific - mRNA processing
Cluster 109: Neurons - Neuronal signaling
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
12,863
8
ENSG00000171747
LGALS4
Galectin 4
[ "P56470" ]
19
38801671-38812945
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025653", "HPA031184", "HPA031185", "HPA031186" ]
[ "GAL4" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes" ]
[ "Plasma membrane" ]
[]
[]
[]
Uncertain
Enhanced
null
7
null
null
null
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 97: Non-specific - Cellular respiration
Cluster 77: Intestine - Digestion
Tissue enriched
Detected in many
14
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
12
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,864
5
ENSG00000171757
LRRC34
Leucine rich repeat containing 34
[ "Q8IZ02" ]
3
169793003-169812986
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA035747" ]
[ "MGC27085" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation" ]
[]
[]
[ "Microtubules" ]
[ "Cytokinetic bridge", "Mitotic spindle", "Primary cilium", "Basal body" ]
[]
[]
Approved
Approved
null
null
Yes
null
null
Cluster 21: Non-specific - Metabolism
Cluster 10: Ciliated cells - Ion channel activity
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
2
0
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
12,865
8
ENSG00000171759
PAH
Phenylalanine hydroxylase
[ "P00439" ]
12
102836889-102958410
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028407", "HPA031642" ]
[ "PH" ]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Phenylalanine catabolism" ]
[ "Allosteric enzyme", "Monooxygenase", "Oxidoreductase" ]
[ "Disease variant", "FDA approved drug targets", "Phenylketonuria" ]
[ "Endoplasmic reticulum", "Vesicles" ]
[]
[]
[]
Approved
Enhanced
null
1
No
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 18: Liver cancer - Metabolism
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 16: Liver & Kidney - Metabolism
Group enriched
Detected in some
12
Cancer enriched
Detected in some
7
Cancer enriched
Detected in many
13
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
12,866
1
ENSG00000171763
SPATA5L1
Spermatogenesis associated 5 like 1
[ "Q9BVQ7" ]
15
45402336-45421415
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043679" ]
[ "FLJ12286", "MGC5347" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Ribosome biogenesis" ]
[ "Hydrolase" ]
[ "Deafness", "Epilepsy", "Intellectual disability", "Non-syndromic deafness" ]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Approved
Uncertain
null
29
null
null
Cluster 33: Non-specific - ATP binding
Cluster 55: Non-specific - Transcription
Cluster 58: Non-specific - Nuclear processes
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
2
2
[]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
12,867
5
ENSG00000171766
GATM
Glycine amidinotransferase
[ "P50440" ]
15
45361124-45402327
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026077" ]
[ "AGAT" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Transferase" ]
[ "Disease variant" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Enhanced
null
10
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 28: Oligodendrocytes - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 70: Non-specific - Protein processing
Group enriched
Detected in all
12
Cancer enriched
Detected in all
4
Cancer enhanced
Detected in all
null
Group enriched
Detected in many
5
Group enriched
Detected in many
5
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,868
8
ENSG00000171772
SYCE1
Synaptonemal complex central element protein 1
[ "Q8N0S2" ]
10
133553901-133569835
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040208" ]
[ "bA108K14.6", "C10orf94", "CT76" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Meiosis" ]
[]
[ "Premature ovarian failure" ]
[ "Nucleoplasm" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Approved
Enhanced
null
48
No
No
Cluster 30: Non-specific - DNA binding
Cluster 37: Neurons - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 67: Testis - Mixed function
Group enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,869
4
ENSG00000171773
NXNL1
Nucleoredoxin like 1
[ "Q96CM4" ]
19
17455425-17460926
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "RDCVF", "TXNL6" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 1: Neuronal - Visual perception
Cluster 101: Choroid plexus epithelial cells - Ion transport
Cluster 48: Ciliated tissues - Cilium organization
Group enriched
Detected in some
22
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,870
1
ENSG00000171790
SLFNL1
Schlafen like 1
[ "Q499Z3" ]
1
41015589-41023237
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA054956" ]
[ "FLJ23878" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
null
null
null
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in some
18
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
12,873
3
ENSG00000171791
BCL2
BCL2 apoptosis regulator
[ "P10415" ]
18
63123346-63320128
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000003", "CAB080071", "CAB080083" ]
[ "Bcl-2", "PPP1R50" ]
[ "Cancer-related genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Apoptosis", "Autophagy" ]
[]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets", "Proto-oncogene" ]
[ "Mitochondria" ]
[]
[]
[]
Enhanced
Enhanced
null
98
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 19: Astrocytes - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
12,874
9
ENSG00000171792
RHNO1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
[ "Q9BSD3" ]
12
2876258-2889524
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C12orf32", "HKMT1188", "MGC13204", "RHINO" ]
[ "Predicted intracellular proteins" ]
[ "Cell cycle", "DNA damage", "DNA repair" ]
[]
[]
[]
[]
[]
[]
null
null
null
13
null
Yes
Cluster 5: Non-specific - Cell proliferation
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 38: Non-specific - Transcription
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
12,875
2
ENSG00000171793
CTPS1
CTP synthase 1
[ "P17812" ]
1
40979300-41012565
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017111", "HPA051322" ]
[ "CTPS", "GATD5A" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Immunity", "Pyrimidine biosynthesis" ]
[ "Ligase" ]
[]
[ "Cytosol" ]
[ "Actin filaments" ]
[]
[]
Approved
Enhanced
null
24
null
Yes
Cluster 13: Non-specific - Mitochondria
Cluster 23: Choroid plexus - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 45: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Cancer enriched
Detected in all
7
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
12,876
5
ENSG00000171794
UTF1
Undifferentiated embryonic cell transcription factor 1
[ "Q5T230" ]
10
133230217-133231558
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB022384" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator" ]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 5: Rhabdoid - Unknown function
Cluster 82: Dendritic cells - Antigen presentation
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
10
Not detected
Not detected
null
Cancer enriched
Detected in single
366
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,877
6
ENSG00000171798
KNDC1
Kinase non-catalytic C-lobe domain containing 1
[ "Q76NI1" ]
10
133160219-133226412
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA039624", "HPA056143" ]
[ "bB439H18.3", "C10orf23", "FLJ25027", "KIAA1768", "RASGEF2", "v-KIND", "Very-KIND" ]
[ "Predicted intracellular proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[]
[ "Plasma membrane", "Cytosol" ]
[ "Vesicles" ]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 27: Breast cancer - Unknown function
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
12,878
1
ENSG00000171804
WDR87
WD repeat domain 87
[ "Q6ZQQ6" ]
19
37884823-37906677
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "NYD-SP11" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
Cluster 4: Non-specific - Transcription
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in single
46
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,879
1
ENSG00000171811
CFAP46
Cilia and flagella associated protein 46
[ "Q8IYW2" ]
10
132808392-132942823
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA037786", "HPA038034", "HPA038867", "HPA038868" ]
[ "bA288G11.4", "bA288G11.5", "bB137A17.2", "bB137A17.3", "C10orf123", "C10orf124", "C10orf92", "C10orf93", "DKFZp434A1721", "FLJ25954", "TTC40" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cilium biogenesis/degradation" ]
[]
[]
[ "Mid piece", "Principal piece", "Annulus" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 51: Myeloma - Immunoglobulins
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Not detected
Not detected
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,881
9
ENSG00000171812
COL8A2
Collagen type VIII alpha 2 chain
[ "P25067" ]
1
36095239-36125222
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049788" ]
[ "FECD", "FECD1", "PPCD", "PPCD2" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Angiogenesis", "Cell adhesion" ]
[]
[ "Corneal dystrophy", "Disease variant" ]
[ "Golgi apparatus" ]
[]
[ "Secreted to extracellular matrix" ]
[ "Cell adhesion" ]
Uncertain
Uncertain
null
null
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 8: Immune cells - Immune response
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[]
[ "Glioblastoma Multiforme", "Ovary Serous Cystadenocarcinoma" ]
[ "Glioblastoma Multiforme", "Ovary Serous Cystadenocarcinoma" ]
12,882
9
ENSG00000171813
PWWP2B
PWWP domain containing 2B
[ "Q6NUJ5" ]
10
132397168-132417859
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038056", "HPA076698", "HPA078118" ]
[ "bA432J24.1", "FLJ46823", "PWWP2" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Approved
null
6
null
null
Cluster 29: Non-specific - Unknown function
Cluster 33: Neurons - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func.
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Glioblastoma Multiforme", "Uterine Corpus Endometrial Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Uterine Corpus Endometrial Carcinoma" ]
12,883
9
ENSG00000171817
ZNF540
Zinc finger protein 540
[ "Q8NDQ6" ]
19
37551406-37614179
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003444" ]
[ "DKFZp547B0714" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Supported
Supported
null
null
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 4: Non-specific - Transcription
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
5
2
4
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
12,885
7
ENSG00000171819
ANGPTL7
Angiopoietin like 7
[ "O43827" ]
1
11189355-11195981
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "AngX", "CDT6" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "No annotated function" ]
null
null
null
14
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Not detected
Not detected
null
Cancer enriched
Detected in some
16
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,886
8
ENSG00000171823
FBXL14
F-box and leucine rich repeat protein 14
[ "Q8N1E6" ]
12
1565993-1594581
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053889" ]
[ "Fbl14", "MGC40195" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
16
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 32: Cerebral cortex - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 75: Non-specific - Chaperones and protein folding
Cluster 36: Brain & Liver - Signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,887
9
ENSG00000171824
EXOSC10
Exosome component 10
[ "Q01780" ]
1
11066618-11099869
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028470", "HPA028484", "CAB037141" ]
[ "p2", "p3", "p4", "PM-Scl", "PM/Scl-100", "PMSCL2", "RRP6", "Rrp6p" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Nonsense-mediated mRNA decay", "rRNA processing" ]
[ "Exonuclease", "Hydrolase", "Nuclease", "RNA-binding" ]
[]
[ "Nucleoli", "Nucleoli rim" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Supported
Supported
null
67
No
No
Cluster 12: Non-specific - Mitochondrial translation
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 37: Non-specific - mRNA processing
Cluster 17: Non-specific - RNA processing
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,888
4
ENSG00000171827
ZNF570
Zinc finger protein 570
[ "Q96NI8" ]
19
37467585-37488652
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA028881" ]
[ "FLJ30791" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 33: Non-specific - ATP binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,889
8
ENSG00000171840
NINJ2
Ninjurin 2
[ "Q9NZG7" ]
12
564296-663589
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA058980", "HPA067226" ]
[]
[ "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Endoplasmic reticulum" ]
[ "Plasma membrane" ]
[]
[]
Approved
null
null
63
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 11: White matter - Signal transduction
Cluster 59: Leukemia - T-cell receptor
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
12,890
9
ENSG00000171843
MLLT3
MLLT3 super elongation complex subunit
[ "P42568" ]
9
20341669-20622499
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001824" ]
[ "AF-9", "AF9", "YEATS3" ]
[ "Cancer-related genes", "Disease related genes", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Cancer-related genes", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
40
null
null
Cluster 11: T-cells - Unknown function
Cluster 51: Neurons - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 77: Intestine - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,891
1
ENSG00000171847
FAM90A1
Family with sequence similarity 90 member A1
[ "Q86YD7" ]
12
8221260-8227618
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA060078" ]
[ "FLJ10408" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Approved
null
null
138
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,892
4
ENSG00000171848
RRM2
Ribonucleotide reductase regulatory subunit M2
[ "P31350" ]
2
10120698-10211725
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA056994" ]
[ "C2orf48", "FLJ25102" ]
[ "Enzymes", "Essential proteins", "FDA approved drug targets", "Metabolic proteins", "Plasma proteins", "Predicted membrane proteins" ]
[ "Deoxyribonucleotide synthesis" ]
[ "Oxidoreductase" ]
[ "FDA approved drug targets" ]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Enhanced
null
23
Yes
Yes
Cluster 15: NK-cells - Unknown function
Cluster 48: Non-specific - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
6
4
4
[]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
12,893
6
ENSG00000171853
TRAPPC12
Trafficking protein particle complex subunit 12
[ "Q8WVT3" ]
2
3379675-3485094
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034799", "HPA043196" ]
[ "CGI-87", "TTC-15", "TTC15" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "ER-Golgi transport", "Transport" ]
[]
[ "Deafness", "Disease variant" ]
[ "Nucleoplasm", "Golgi apparatus" ]
[]
[]
[]
Supported
Uncertain
null
23
null
null
Cluster 29: Non-specific - Unknown function
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 102: Non-specific - Mixed function
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
12,894
2
ENSG00000171855
IFNB1
Interferon beta 1
[ "P01574" ]
9
21077104-21077942
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA073843" ]
[ "IFB", "IFF", "IFNB" ]
[ "Cancer-related genes", "Predicted secreted proteins" ]
[ "Antiviral defense" ]
[ "Cytokine" ]
[ "Cancer-related genes" ]
[]
[]
[ "Secreted to blood" ]
[ "Interferon" ]
null
Supported
null
1
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 31: Non-specific - Antiviral immune response
Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
65
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,895
4
ENSG00000171858
RPS21
Ribosomal protein S21
[ "P63220" ]
20
62387103-62388520
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003371" ]
[ "S21" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Endoplasmic reticulum", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
95
null
null
Cluster 24: Non-specific - Transcription
Cluster 28: Oligodendrocytes - Mixed function
Cluster 25: Non-specific - Ribosome
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
12,896
4
ENSG00000171860
C3AR1
Complement C3a receptor 1
[ "Q16581" ]
12
8056844-8066359
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009405" ]
[ "AZ3B", "C3AR" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Chemotaxis" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 20: Macrophages & Microglia - Immune response
Cluster 49: HMC-1 - Innate immune response
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
5
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
12,897
1
ENSG00000171861
MRM3
Mitochondrial rRNA methyltransferase 3
[ "Q9HC36" ]
17
782353-792509
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022534", "HPA023031", "HPA023292" ]
[ "FLJ10581", "HC90", "RMTL1", "RNMTL1" ]
[ "Predicted intracellular proteins" ]
[ "rRNA processing" ]
[ "Methyltransferase", "Transferase" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Supported
Enhanced
null
46
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 16: Non-specific - Transcription
Cluster 42: Non-specific - Unknown function
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,898
1
ENSG00000171862
PTEN
Phosphatase and tensin homolog
[ "P60484" ]
10
87862563-87971930
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004076", "HPA031335", "CAB080153", "CAB080155", "CAB080157" ]
[ "BZS", "MHAM", "MMAC1", "PTEN1", "TEP1" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Apoptosis", "Lipid metabolism", "Neurogenesis" ]
[ "Hydrolase", "Protein phosphatase" ]
[ "Autism spectrum disorder", "Cancer-related genes", "Disease variant", "Tumor suppressor" ]
[ "Nucleoplasm", "Cytosol" ]
[ "Mid piece", "Principal piece" ]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Supported
Approved
null
159
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 16: Non-specific - Transcription
Cluster 52: Non-specific - Mitochondria
Cluster 22: Non-specific - Basic cellular functions
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
0
0
0
[]
[]
[]
12,899
9
ENSG00000171863
RPS7
Ribosomal protein S7
[ "P62081" ]
2
3575260-3580920
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA056586" ]
[ "eS7", "S7" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[ "Diamond-Blackfan anemia" ]
[ "Endoplasmic reticulum", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
157
null
Yes
Cluster 18: Non-specific - Translation
Cluster 7: Non-specific - Ribosome
Cluster 25: Non-specific - Ribosome
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
12,900
6
ENSG00000171864
PRND
Prion like protein doppel
[ "Q9UKY0" ]
20
4721909-4728460
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043373" ]
[ "dJ1068H6.4", "DOPPEL", "DPL", "PrPLP" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Fertilization" ]
[ "Prion" ]
[]
[]
[]
[]
[]
null
Enhanced
null
4
null
null
null
Cluster 36: Choroid plexus - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 43: Sertoli cells - Spermatogenesis microenvironment
Cluster 56: Ciliated tissues - Cilium organization
Group enriched
Detected in some
16
Cancer enriched
Detected in some
4
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
15
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,901
9
ENSG00000171867
PRNP
Prion protein
[ "P04156" ]
20
4686350-4701590
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042754", "HPA043398" ]
[ "AltPrP", "CD230", "CJD", "GSS", "PRIP", "PRP" ]
[ "CD markers", "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Cell cycle", "Growth arrest" ]
[ "Prion" ]
[ "Amyloidosis", "Disease variant" ]
[ "Nuclear membrane", "Cytosol" ]
[ "Vesicles" ]
[]
[]
Approved
Enhanced
null
320
null
Yes
Cluster 41: Basophils - Unknown function
Cluster 23: Choroid plexus - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enriched
Detected in all
9
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
12,903
3
ENSG00000171872
KLF17
KLF transcription factor 17
[ "Q5JT82" ]
1
44118821-44135140
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024629" ]
[ "FLJ40160", "Zfp393", "ZNF393" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding", "Repressor" ]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
null
Cluster 72: Neuronal - Signal transduction
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 67: Testis - Mixed function
Tissue enriched
Detected in some
7
Cancer enriched
Detected in single
7
Cancer enriched
Detected in single
20
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,904
2
ENSG00000171873
ADRA1D
Adrenoceptor alpha 1D
[ "P25100" ]
20
4220630-4249287
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038789" ]
[ "ADRA1", "ADRA1A", "ADRA1R" ]
[ "FDA approved drug targets", "G-protein coupled receptors", "Plasma proteins", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
Uncertain
null
13
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 110: Mural cells - ECM organization
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,905
7
ENSG00000171877
FRMD5
FERM domain containing 5
[ "Q7Z6J6" ]
15
43870761-44195271
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MGC14161" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[ "Disease variant", "Intellectual disability" ]
[]
[]
[]
[]
null
null
null
6
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 72: Neuronal - Signal transduction
Cluster 80: Oligodendrocytes - Myelination
Cluster 35: Non-specific - Mixed function
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Glioblastoma Multiforme" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
12,906
4
ENSG00000171885
AQP4
Aquaporin 4
[ "P55087" ]
18
26852043-26865771
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005079", "HPA014784", "CAB058689" ]
[ "AQP-4", "hAQP4", "MIWC" ]
[ "Human disease related genes", "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[ "Disease variant" ]
[ "Plasma membrane" ]
[ "Cell Junctions" ]
[]
[]
Supported
Enhanced
Supported
4
null
null
null
Cluster 39: Astrocytes - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 73: Brain - Neuronal signaling
Group enriched
Detected in many
4
Group enriched
Detected in some
4
Cancer enriched
Detected in some
16
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,907
8
ENSG00000171903
CYP4F11
Cytochrome P450 family 4 subfamily F member 11
[ "Q9HBI6" ]
19
15912367-15934867
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017265", "CAB033648", "HPA058960" ]
[]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Fatty acid metabolism", "Lipid metabolism" ]
[ "Monooxygenase", "Oxidoreductase" ]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
Cluster 39: Astrocytes - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Breast Invasive Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
12,908
4
ENSG00000171914
TLN2
Talin 2
[ "Q9Y4G6" ]
15
62390526-62844631
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017194", "HPA051828", "HPA054787" ]
[ "ILWEQ", "KIAA0320" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Focal adhesion sites", "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
6
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 89: Adipocytes - Lipid metabolism
Cluster 72: Kidney - Transmembrane transport
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
4
2
3
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Rectum Adenocarcinoma" ]
12,909
3
ENSG00000171916
LGALS9C
Galectin 9C
[ "Q6DKI2" ]
17
18476737-18494945
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046876", "HPA047218" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
28
null
null
Cluster 35: Neutrophils - Protein binding
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 102: Non-specific - Mixed function
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Group enriched
Detected in some
6
2
0
2
[ "Breast Invasive Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Rectum Adenocarcinoma" ]
12,910
4
ENSG00000171928
TVP23B
Trans-golgi network vesicle protein 23 homolog B
[ "Q9NYZ1" ]
17
18781111-18806714
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019585", "HPA065603" ]
[ "CGI-148", "FAM18B", "FAM18B1", "YDR084C" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Supported
Uncertain
null
23
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 21: Non-specific - Metabolism
Cluster 42: Non-specific - Unknown function
Cluster 67: Plasma cells - Plasma cell differentiation
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,911
8
ENSG00000171931
FBXW10
F-box and WD repeat domain containing 10
[ "Q5XX13" ]
17
18744026-18779349
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA047457" ]
[ "C17orf1", "C17orf1A", "Fbw10", "HREP", "SM2SH2" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
2
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 67: Testis - Mixed function
Tissue enriched
Detected in some
7
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,912
9
ENSG00000171936
OR10H3
Olfactory receptor family 10 subfamily H member 3
[ "O60404" ]
19
15737985-15742343
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
Evidence at transcript level
[]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
Cluster 108: Fibroblasts - ECM organization
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,913
9
ENSG00000171940
ZNF217
Zinc finger protein 217
[ "O75362" ]
20
53567071-53609907
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051857" ]
[ "ZABC1" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nuclear speckles" ]
[ "Mitochondria" ]
[]
[]
Enhanced
Approved
null
22
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 39: Astrocytes - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 51: Lymphoid tissue - Adaptive immune response
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,914
8
ENSG00000171942
OR10H2
Olfactory receptor family 10 subfamily H member 2
[ "O60403" ]
19
15728024-15729052
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
Evidence at transcript level
[]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
2
null
null
null
null
null
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,915
6
ENSG00000171943
SRGAP2C
SLIT-ROBO Rho GTPase activating protein 2C
[ "P0DJJ0" ]
1
121184811-121392874
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA078079" ]
[ "SRGAP2P1" ]
[ "Predicted intracellular proteins" ]
[ "Neurogenesis" ]
[]
[]
[ "Cytosol" ]
[ "Centrosome", "Basal body" ]
[]
[]
Approved
null
null
9
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 25: Non-specific - Transcription
Cluster 69: Skin cancer - ECM organization
Cluster 57: Podocytes - Glomerular filtration
Cluster 2: Non-specific - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
7
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
12,916
7
ENSG00000171944
OR52A5
Olfactory receptor family 52 subfamily A member 5
[ "Q9H2C5" ]
11
5128776-5138356
Evidence at transcript level
No human protein/transcript evidence
No human protein/transcript evidence
Evidence at transcript level
[]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
Cluster 59: Leukemia - T-cell receptor
Cluster 106: Spermatogonia - Spermatogonial differentiation
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
12,917
3
ENSG00000171951
SCG2
Secretogranin II
[ "P13521" ]
2
223596940-223602361
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011893", "HPA075062" ]
[ "CHGC", "SgII", "SN" ]
[ "Plasma proteins", "Predicted secreted proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[ "Vesicles" ]
[ "Secreted to blood" ]
[ "No annotated function" ]
Approved
Enhanced
Supported
3
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 36: Brain & Liver - Signaling
Group enriched
Detected in many
7
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
7
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
12,918
6
ENSG00000171953
ATPAF2
ATP synthase mitochondrial F1 complex assembly factor 2
[ "Q8N5M1" ]
17
17977409-18039209
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023329", "HPA059422" ]
[ "ATP12", "Atp12p", "LP3663", "MGC29736" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Chaperone" ]
[ "Disease variant", "Primary mitochondrial disease" ]
[ "Cytosol" ]
[]
[]
[]
Uncertain
Supported
null
78
No
No
Cluster 10: Non-specific - Membrane trafficking
Cluster 25: Non-specific - Transcription
Cluster 42: Non-specific - Unknown function
Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
12,919
4
ENSG00000171954
CYP4F22
Cytochrome P450 family 4 subfamily F member 22
[ "Q6NT55" ]
19
15508525-15552317
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA058960" ]
[ "FLJ39501" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[ "Monooxygenase", "Oxidoreductase" ]
[ "Ichthyosis" ]
[]
[]
[]
[]
null
Uncertain
null
11
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
null
Cluster 12: Bone cancer - Neuronal signaling
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
31
Group enriched
Detected in many
6
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
5
0
0
0
[]
[]
[]
12,920
8
ENSG00000171956
FOXB1
Forkhead box B1
[ "Q99853" ]
15
60004234-60061730
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA073369" ]
[ "FKH5", "HFKH-5" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Mitochondria" ]
[]
[]
[]
Approved
null
null
5
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in single
6
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Immune cell enriched
Detected in single
5
0
0
0
[]
[]
[]
12,921
6
ENSG00000171960
PPIH
Peptidylprolyl isomerase H
[ "O43447" ]
1
42658335-42676758
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA059019" ]
[ "CYP-20", "CYPH", "MGC5016", "SnuCyp-20", "USA-CYP" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "Chaperone", "Isomerase", "Rotamase" ]
[]
[]
[]
[]
[]
null
Approved
null
42
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 34: Non-specific - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[]
[ "Bladder Urothelial Carcinoma", "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,922
9
ENSG00000171962
DRC3
Dynein regulatory complex subunit 3
[ "Q9H069" ]
17
17972813-18016889
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036040", "HPA036041" ]
[ "CFAP134", "DKFZP586M1120", "LRRC48" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mid piece", "Principal piece", "End piece" ]
[]
[]
[]
Approved
Approved
null
null
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
12,923
4
ENSG00000171970
ZNF57
Zinc finger protein 57
[ "Q68EA5" ]
19
2900928-2918473
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA061915" ]
[ "ZNF424" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoli" ]
[]
[]
[]
Approved
null
null
17
null
null
Cluster 33: Non-specific - ATP binding
Cluster 35: Non-specific - DNA binding
Cluster 4: Non-specific - Transcription
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 57: Testis - Spermatogenesis
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
12,924
2
ENSG00000171984
SHLD1
Shieldin complex subunit 1
[ "Q8IYI0" ]
20
5750393-5864395
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040749" ]
[ "C20orf196", "FLJ25067", "RINN3" ]
[ "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[]
[]
[ "Endoplasmic reticulum", "Golgi apparatus", "Vesicles" ]
[]
[]
[]
Approved
Approved
null
10
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 25: Non-specific - Transcription
Cluster 46: Lymphoma - Humoral immune response
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
12,925
1
ENSG00000171988
JMJD1C
Jumonji domain containing 1C
[ "Q15652" ]
10
63167221-63521850
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA056175", "HPA066195" ]
[ "DKFZp761F0118", "FLJ14374", "KDM3C", "KIAA1380", "TRIP8" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Dioxygenase", "Oxidoreductase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
11
No
No
Cluster 20: Non-specific - DNA binding
Cluster 35: Non-specific - DNA binding
Cluster 52: Non-specific - Mitochondria
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in many
null
2
2
1
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
12,926
1