ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000172466
ZNF24
Zinc finger protein 24
[ "P17028" ]
18
35332227-35345482
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024062", "CAB025642" ]
[ "KOX17", "Zfp191", "ZNF191", "ZSCAN3" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
72
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 17: Non-specific - RNA processing
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
13,038
3
ENSG00000172468
HSFY1
Heat shock transcription factor Y-linked 1
[ "Q96LI6" ]
Y
18546691-18588963
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA074968" ]
[ "HSF2L", "HSFY" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
null
null
24
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in single
18
Not detected
Not detected
null
Cancer enriched
Detected in single
4
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,039
8
ENSG00000172469
MANEA
Mannosidase endo-alpha
[ "Q5SRI9" ]
6
95577485-95609470
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011046", "HPA011069" ]
[ "FLJ12838", "mandaselin" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Supported
Enhanced
null
2
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 55: Non-specific - Transcription
Cluster 51: Myeloma - Immunoglobulins
Cluster 67: Plasma cells - Plasma cell differentiation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,040
3
ENSG00000172476
RAB40A
RAB40A, member RAS oncogene family
[ "Q8WXH6" ]
X
103499130-103519489
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA076172" ]
[ "Rar-2", "RAR2A" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Hydrolase" ]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[]
[]
[]
Uncertain
null
null
8
null
null
null
Cluster 23: Choroid plexus - Mixed function
Cluster 34: Testis cancer - Unknown function
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 21: Testis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,041
5
ENSG00000172478
MAB21L4
Mab-21 like 4
[ "Q08AI8" ]
2
240886048-240896889
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA052722" ]
[ "C2orf54", "FLJ22671" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Golgi apparatus" ]
[]
[]
[]
Approved
null
null
4
null
null
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 84: Apical squamous epithelium - Cornification
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,042
4
ENSG00000172482
AGXT
Alanine--glyoxylate aminotransferase
[ "P21549" ]
2
240868824-240880502
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035370", "HPA035371" ]
[ "AGT", "AGT1", "AGXT1", "PH1", "Ser-PyrAT", "SPAT", "SPT", "TLH6" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Aminotransferase", "Transferase" ]
[ "Disease variant" ]
[ "Vesicles" ]
[]
[]
[]
Supported
Enhanced
null
30
null
null
null
null
Cluster 18: Liver cancer - Metabolism
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 31: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
190
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in single
445
Cell type enriched
Detected in some
52
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
13,043
4
ENSG00000172487
OR8J1
Olfactory receptor family 8 subfamily J member 1
[ "Q8NGP2" ]
11
56354291-56361511
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
Evidence at transcript level
[]
[]
[ "G-protein coupled receptors", "Plasma proteins", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,044
3
ENSG00000172489
OR5T3
Olfactory receptor family 5 subfamily T member 3
[]
11
56252254-56253222
No human protein/transcript evidence
No human protein/transcript evidence
null
null
[]
[ "OR5T3Q" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,045
2
ENSG00000172493
AFF1
ALF transcription elongation factor 1
[ "P51825" ]
4
86935002-87141039
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA069947" ]
[ "AF-4", "AF4", "FEL", "MLLT2", "PBM1" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes", "Proto-oncogene" ]
[ "Nucleoplasm", "Mitochondria" ]
[]
[]
[]
Approved
null
null
18
No
No
Cluster 7: Non-specific - Innate immune response
Cluster 8: Immune cells - Immune response
Cluster 51: Myeloma - Immunoglobulins
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
13,046
4
ENSG00000172497
ACOT12
Acyl-CoA thioesterase 12
[ "Q8WYK0" ]
5
81329996-81394179
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA037723" ]
[ "Cach", "STARD15", "THEAL" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Fatty acid metabolism", "Lipid metabolism" ]
[ "Hydrolase", "Serine esterase" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm", "Cytokinetic bridge" ]
[]
[]
Approved
null
null
8
Yes
null
null
Cluster 14: Neurons - Synaptic function
Cluster 71: Lymphoma - Inflammatory response
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
36
Cancer enhanced
Detected in single
null
Cancer enriched
Detected in single
43
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
2
0
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
13,047
7
ENSG00000172500
FIBP
FGF1 intracellular binding protein
[ "O43427" ]
11
65883740-65888531
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011729" ]
[ "FGFIBP" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant" ]
[ "Nuclear speckles" ]
[]
[]
[]
Supported
Approved
null
5
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 24: Non-specific - Unknown function
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
13,048
7
ENSG00000172508
CARNS1
Carnosine synthase 1
[ "A5YM72" ]
11
67414968-67425607
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038569" ]
[ "ATPGD1", "KIAA1394" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Ligase" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Uncertain
Enhanced
null
1
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 30: White matter - Myelination
Cluster 72: Neuronal - Signal transduction
Cluster 80: Oligodendrocytes - Myelination
Cluster 3: Oligodendrocytes - Myelination
Group enriched
Detected in some
4
Not detected
Not detected
null
Group enriched
Detected in some
8
Cell type enriched
Detected in some
8
Low immune cell specificity
Detected in some
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
13,049
6
ENSG00000172519
OR10H5
Olfactory receptor family 10 subfamily H member 5
[ "Q8NGA6" ]
19
15787661-15800357
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 48: Non-specific - Mixed function
null
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
null
Not detected
Not detected
null
Not detected
Not detected
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
13,050
1
ENSG00000172530
BANP
BTG3 associated nuclear protein
[ "Q8N9N5" ]
16
87949244-88077318
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047164" ]
[ "BEND1", "DKFZp761H172", "FLJ10177", "FLJ20538", "SMAR1", "SMARBP1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Developmental protein", "DNA-binding", "Repressor", "RNA-binding" ]
[ "Tumor suppressor" ]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Supported
Approved
null
83
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 25: Non-specific - Transcription
Cluster 68: Non-specific - Cell cycle regulation
Cluster 103: Non-specific - Basic cellular processes
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
2
3
[ "Glioblastoma Multiforme" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Thyroid Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Thyroid Carcinoma" ]
13,051
1
ENSG00000172531
PPP1CA
Protein phosphatase 1 catalytic subunit alpha
[ "P62136" ]
11
67398181-67421183
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004545", "HPA046833" ]
[ "PP-1A", "PP1A", "PP1alpha", "PPP1A" ]
[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Carbohydrate metabolism", "Cell cycle", "Cell division", "Glycogen metabolism", "Host-virus interaction" ]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nucleoplasm", "Plasma membrane", "Cytosol" ]
[ "Flagellar centriole", "Mid piece", "End piece" ]
[]
[]
Supported
Enhanced
null
293
null
null
Cluster 25: Non-specific - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
13,052
4
ENSG00000172534
HCFC1
Host cell factor C1
[ "P51610" ]
X
153947557-153971818
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA078588" ]
[ "CFF", "HCF-1", "HCF1", "HFC1", "MGC70925", "MRX3", "PPP1R89", "VCAF" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Host-virus interaction" ]
[ "Chromatin regulator" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
129
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 32: Cerebral cortex - Mixed function
Cluster 54: Non-specific - Transcription
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
13,053
5
ENSG00000172538
FAM170B
Family with sequence similarity 170 member B
[ "A6NMN3" ]
10
49131154-49134021
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043899", "HPA050610" ]
[ "AC084727.4", "C10orf73" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
Cluster 55: Lymphoma - Immune response
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
61
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
4
Immune cell enriched
Detected in single
20
0
0
0
[]
[]
[]
13,054
4
ENSG00000172543
CTSW
Cathepsin W
[ "P56202" ]
11
65879809-65883741
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB016345", "HPA066903" ]
[]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Enhanced
null
null
null
null
Cluster 15: NK-cells - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 59: Leukemia - T-cell receptor
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 15: Bone marrow - Innate immune response
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
16
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in all
8
2
0
2
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,055
9
ENSG00000172551
MUCL1
Mucin like 1
[ "Q96DR8" ]
12
54830518-54896008
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039093" ]
[ "SBEM" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in other tissues" ]
[ "No annotated function" ]
null
Enhanced
null
3
null
null
null
null
Cluster 27: Breast cancer - Unknown function
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 55: Breast - Lactation
Group enriched
Detected in many
10
Cancer enriched
Detected in some
40
Cancer enriched
Detected in many
32
Cell type enriched
Detected in some
11
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,057
9
ENSG00000172554
SNTG2
Syntrophin gamma 2
[ "Q9NY99" ]
2
950849-1367613
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA065258", "HPA077904" ]
[ "G2SYN", "SYN5" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[ "Plasma membrane" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Approved
null
10
null
null
null
Cluster 49: Hindbrain - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in some
null
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,058
4
ENSG00000172572
PDE3A
Phosphodiesterase 3A
[ "Q14432" ]
12
20368537-20688583
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014492", "HPA074258" ]
[ "CGI-PDE" ]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase" ]
[ "Disease variant", "FDA approved drug targets" ]
[ "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
7
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 3: Rhabdoid - Membrane components
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 35: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,060
1
ENSG00000172575
RASGRP1
RAS guanyl releasing protein 1
[ "O95267" ]
15
38488103-38565575
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039389" ]
[ "CalDAG-GEFII", "RASGRP" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[ "Differentiation" ]
[ "Guanine-nucleotide releasing factor" ]
[ "Disease variant", "Systemic lupus erythematosus" ]
[ "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Supported
null
null
3
null
null
Cluster 1: T-cells - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 50: Lymphoma - Unknown function
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 61: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Group enriched
Detected in many
4
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,061
4
ENSG00000172578
KLHL6
Kelch like family member 6
[ "Q8WZ60" ]
3
183487551-183555706
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024512" ]
[ "FLJ00029" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane", "Centriolar satellite" ]
[ "Microtubules", "Mitotic spindle", "Cytosol" ]
[]
[]
Approved
Uncertain
null
12
Yes
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 20: Macrophages & Microglia - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 18: Lymphoid tissue - Immune response
Tissue enriched
Detected in some
6
Group enriched
Detected in some
78
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Head and Neck Squamous Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Lung Adenocarcinoma" ]
13,062
9
ENSG00000172590
MRPL52
Mitochondrial ribosomal protein L52
[ "Q86TS9" ]
14
22829879-22835037
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012319" ]
[]
[ "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Mitochondria" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Approved
null
98
Yes
No
Cluster 12: Non-specific - Mitochondrial translation
Cluster 45: Non-specific - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 97: Non-specific - Cellular respiration
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
13,064
4
ENSG00000172594
SMPDL3A
Sphingomyelin phosphodiesterase acid like 3A
[ "Q92484" ]
6
122789049-122809720
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA030148" ]
[ "ASM3A", "ASML3a", "FLJ20177", "yR36GH4.1" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Nucleoplasm", "Nucleoli", "Mitochondria" ]
[]
[ "Secreted to blood" ]
[ "Enzyme" ]
Approved
Uncertain
null
null
No
No
Cluster 32: Basophils - Transcription
Cluster 50: Non-specific - Nucleic acid binding
Cluster 71: Lymphoma - Inflammatory response
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
11
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,065
2
ENSG00000172602
RND1
Rho family GTPase 1
[ "Q92730" ]
12
48857145-48865870
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA077800" ]
[ "ARHS", "Rho6", "RHOS" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles", "Plasma membrane", "Actin filaments" ]
[]
[]
[]
Supported
null
null
15
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 36: Brain & Liver - Signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
13,066
1
ENSG00000172613
RAD9A
RAD9 checkpoint clamp component A
[ "Q99638" ]
11
67317871-67398410
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006725", "HPA048155", "CAB079979" ]
[ "RAD9" ]
[ "Enzymes", "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "DNA damage" ]
[ "Exonuclease", "Hydrolase", "Nuclease" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Enhanced
Enhanced
null
43
null
null
Cluster 22: Eosinophils - Transcription
Cluster 17: Choroid plexus - Cilium
Cluster 24: Non-specific - Unknown function
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Head and Neck Squamous Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Rectum Adenocarcinoma" ]
13,067
9
ENSG00000172638
EFEMP2
EGF containing fibulin extracellular matrix protein 2
[ "O95967" ]
11
65866441-65873592
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA023270" ]
[ "FBLN4", "UPH1" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[ "Disease variant" ]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
null
Approved
null
93
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
13,068
7
ENSG00000172640
OR10AD1
Olfactory receptor family 10 subfamily AD member 1
[ "Q8NGE0" ]
12
48202339-48203292
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA049913" ]
[ "OR10AD1P" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 51: Myeloma - Immunoglobulins
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 42: Retina - Visual perception
Tissue enhanced
Detected in single
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,069
2
ENSG00000172650
AGAP5
ArfGAP with GTPase domain, ankyrin repeat and PH domain 5
[ "A6NIR3" ]
10
73674287-73698109
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA042490" ]
[ "CTGLF2", "Em:AC073389.1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 32: Basophils - Transcription
Cluster 48: Non-specific - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 102: Non-specific - Mixed function
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,070
9
ENSG00000172661
WASHC2C
WASH complex subunit 2C
[ "Q9Y4E1" ]
10
45727200-45792964
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047844", "HPA060975", "HPA061022" ]
[ "Em:AC012044.3", "FAM21C", "KIAA0592" ]
[ "Predicted intracellular proteins", "Transporters" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Vesicles" ]
[ "Nucleoli", "Cytosol" ]
[]
[]
Supported
Supported
null
15
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 6: Non-specific - Immune response
Cluster 52: Non-specific - Mitochondria
Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
13,071
4
ENSG00000172663
TMEM134
Transmembrane protein 134
[ "Q9H6X4" ]
11
67461710-67469272
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043744" ]
[ "FLJ21749" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Host-virus interaction" ]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
null
null
null
Cluster 29: Non-specific - Unknown function
Cluster 7: Non-specific - Ribosome
Cluster 24: Non-specific - Unknown function
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
13,072
3
ENSG00000172667
ZMAT3
Zinc finger matrin-type 3
[ "Q9HA38" ]
3
178960121-179072215
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA027569", "HPA028671", "HPA054356" ]
[ "FLJ12296", "MGC10613", "PAG608", "WIG-1", "WIG1" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis", "DNA damage", "Growth regulation", "Protein transport", "Translocation", "Transport" ]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Enhanced
null
9
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 40: Non-specific - Unknown function
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 36: Brain & Liver - Signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[]
[ "Glioblastoma Multiforme", "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Glioblastoma Multiforme", "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
13,073
2
ENSG00000172671
ZFAND4
Zinc finger AN1-type containing 4
[ "Q86XD8" ]
10
45615500-45672780
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
[ "HPA057543", "HPA074103" ]
[ "ANUBL1", "FLJ40185" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
Enhanced
null
null
null
null
Cluster 14: Non-specific - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 46: Lymphoma - Humoral immune response
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in many
6
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
13,074
2
ENSG00000172673
THEMIS
Thymocyte selection associated
[ "Q8N1K5" ]
6
127708072-127918631
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031422", "HPA031425" ]
[ "bA325O24.3", "bA325O24.4", "C6orf190", "C6orf207", "FLJ40584", "TSEPA" ]
[ "Predicted intracellular proteins" ]
[ "Adaptive immunity", "Immunity" ]
[ "Developmental protein" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
5
null
null
Cluster 11: T-cells - Unknown function
Cluster 53: Neurons - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 102: Non-specific - Mixed function
Cluster 80: Thymus - Adaptive immune response
Tissue enriched
Detected in some
11
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in some
8
Group enriched
Detected in many
21
0
0
0
[]
[]
[]
13,075
4
ENSG00000172680
MOS
MOS proto-oncogene, serine/threonine kinase
[ "P00540" ]
8
56112942-56113982
Evidence at protein level
No human protein/transcript evidence
Evidence at protein level
Evidence at protein level
[]
[]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Disease variant", "Proto-oncogene" ]
[]
[]
[]
[]
null
null
null
59
null
null
null
null
Cluster 4: Non-specific - Transcription
Cluster 53: Late primary spermatocytes - Meiotic division & transition
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,076
9
ENSG00000172687
ZNF738
Zinc finger protein 738
[ "Q8NE65" ]
19
21358930-21388582
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA059135" ]
[]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
4
null
null
Cluster 29: Non-specific - Unknown function
Cluster 26: Oligodendrocytes - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
13,077
9
ENSG00000172689
MS4A10
Membrane spanning 4-domains A10
[ "Q96PG2" ]
11
60785333-60801305
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA014778" ]
[ "CD20L7", "MS4A9" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
Uncertain
null
3
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in single
102
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
49
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,078
3
ENSG00000172716
SLFN11
Schlafen family member 11
[ "Q7Z7L1" ]
17
35350305-35373701
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023030", "HPA062062" ]
[ "FLJ34922" ]
[ "Predicted intracellular proteins" ]
[ "Antiviral defense", "DNA damage", "Immunity" ]
[ "DNA-binding", "Endonuclease", "Helicase", "Hydrolase", "Nuclease", "RNA-binding", "tRNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Uncertain
null
18
No
null
Cluster 13: Non-specific - Mitochondria
Cluster 49: Hindbrain - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 103: Non-specific - Basic cellular processes
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
13,079
5
ENSG00000172717
GARIN2
Golgi associated RAB2 interactor family member 2
[ "Q8N9W8" ]
14
67189393-67228550
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C14orf54", "FAM71D", "GARI-L2" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in single
26
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Group enriched
Detected in many
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,080
8
ENSG00000172725
CORO1B
Coronin 1B
[ "Q9BR76" ]
11
67435510-67443821
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017616", "HPA040113", "HPA070456" ]
[ "coronin-2" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
25
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 20: Macrophages & Microglia - Immune response
Cluster 24: Non-specific - Unknown function
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
0
0
0
[]
[]
[]
13,082
2
ENSG00000172728
FUT10
Fucosyltransferase 10
[ "Q6P4F1" ]
8
33370824-33473146
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053970", "HPA058655" ]
[]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Nucleoplasm", "Endoplasmic reticulum", "Golgi apparatus" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 33: Non-specific - ATP binding
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 40: Non-specific - Unknown function
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,083
5
ENSG00000172731
LRRC20
Leucine rich repeat containing 20
[ "Q8TCA0" ]
10
70298970-70382650
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039630" ]
[ "FLJ10751", "FLJ10844" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
null
null
4
No
No
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 30: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in all
6
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Papillary Cell Carcinoma" ]
13,084
1
ENSG00000172732
MUS81
MUS81 structure-specific endonuclease subunit
[ "Q96NY9" ]
11
65857126-65867653
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059530" ]
[ "FLJ44872", "SLX3" ]
[ "Predicted intracellular proteins" ]
[ "DNA damage", "DNA recombination", "DNA repair" ]
[ "Endonuclease", "Hydrolase", "Nuclease" ]
[]
[ "Nucleoli fibrillar center" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Approved
null
25
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 24: Non-specific - Unknown function
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Glioblastoma Multiforme", "Ovary Serous Cystadenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
13,085
1
ENSG00000172733
PURG
Purine rich element binding protein G
[ "Q9UJV8" ]
8
30995802-31033715
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA047746" ]
[ "PURG-A", "PURG-B" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli", "Plasma membrane", "Cytokinetic bridge", "Centrosome", "Basal body" ]
[]
[]
Approved
Enhanced
null
64
Yes
null
null
Cluster 2: Neurons - Nucleosome
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
5
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,086
1
ENSG00000172738
TMEM217
Transmembrane protein 217
[ "Q8N7C4" ]
6
37212180-37258155
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA045432", "HPA071187" ]
[ "C6orf128", "dJ355M6.2" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Approved
null
null
null
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 48: Adipocytes & Endothelial cells - Angiogenesis
Cluster 102: Non-specific - Mixed function
Cluster 57: Testis - Spermatogenesis
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
13,087
5
ENSG00000172742
OR4D9
Olfactory receptor family 4 subfamily D member 9
[ "Q8NGE8" ]
11
59511368-59520703
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
[]
[]
[ "Essential proteins", "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 20: Non-specific - DNA binding
Cluster 48: Non-specific - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 104: Brain endothelial cells - Blood brain barrier
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in single
6
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
13,088
5
ENSG00000172748
ZNF596
Zinc finger protein 596
[ "Q8TC21" ]
8
232137-264703
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA055463" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoli", "Mitochondria" ]
[]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 15: Non-specific - Transcription
Cluster 56: Non-specific - Sensory perception
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 46: Brain & retina - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
13,089
8
ENSG00000172765
TMCC1
Transmembrane and coiled-coil domain family 1
[ "O94876" ]
3
129647792-129893711
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA053894" ]
[ "KIAA0779" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Transport" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
2
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 15: Non-specific - Transcription
Cluster 15: Kidney cancer - Membrane components
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 45: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cancer enriched
Detected in all
4
Cell type enhanced
Detected in all
null
Immune cell enriched
Detected in many
5
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
13,092
8
ENSG00000172769
OR5B3
Olfactory receptor family 5 subfamily B member 3
[ "Q8NH48" ]
11
58402464-58406874
No human protein/transcript evidence
No human protein/transcript evidence
No human protein/transcript evidence
No human protein/transcript evidence
[]
[ "OR5B13", "OST129" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
Cluster 56: Non-specific - Sensory perception
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,094
4
ENSG00000172771
EFCAB12
EF-hand calcium binding domain 12
[ "Q6NXP0" ]
3
129401321-129428651
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA037694", "HPA057532" ]
[ "C3orf25" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies", "Midbody ring" ]
[]
[]
Approved
Uncertain
Supported
2
Yes
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 60: Prostate cancer - Unknown function
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in single
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,095
5
ENSG00000172772
OR10W1
Olfactory receptor family 10 subfamily W member 1
[ "Q8NGF6" ]
11
58266792-58268260
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
Evidence at transcript level
[]
[ "OR10W1P" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
null
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,096
9
ENSG00000172775
PSME3IP1
Proteasome activator subunit 3 interacting protein 1
[ "Q9GZU8" ]
16
57152466-57186116
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA054382", "HPA059652" ]
[ "C16orf94", "FAM192A", "NIP30", "PIP30" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
Uncertain
null
53
null
null
Cluster 41: Basophils - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 68: Non-specific - Cell cycle regulation
Cluster 7: Non-specific - Transcription
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
13,097
5
ENSG00000172780
RAB43
RAB43, member RAS oncogene family
[ "Q86YS6" ]
3
129087569-129122801
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046840", "HPA060085" ]
[ "ISY1", "RAB11B", "RAB41" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[]
[]
[]
Supported
Enhanced
null
16
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 15: Non-specific - Transcription
Cluster 63: Non-specific - Protein processing
Cluster 22: Non-specific - Basic cellular functions
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in many
null
0
0
0
[]
[]
[]
13,098
6
ENSG00000172782
FADS6
Fatty acid desaturase 6
[]
17
74877302-74893781
Evidence at transcript level
Evidence at transcript level
null
null
[ "HPA016802" ]
[]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 20: Non-specific - DNA binding
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 61: BICR 18 - Protein kinases
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 22: Epididymis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
13,099
9
ENSG00000172785
ZNG1A
Zn regulated GTPase metalloprotein activator 1A
[ "Q9BRT8" ]
9
120837-179147
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042759", "HPA042813" ]
[ "CBWD1" ]
[ "Disease related genes", "Predicted intracellular proteins" ]
[]
[ "Chaperone", "Hydrolase" ]
[]
[ "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
47
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 60: Prostate cancer - Unknown function
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,100
2
ENSG00000172789
HOXC5
Homeobox C5
[ "Q00444" ]
12
54033050-54035361
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026794" ]
[ "HOX3", "HOX3D" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Cell Junctions" ]
[]
[]
Supported
Uncertain
null
9
null
null
null
Cluster 49: Hindbrain - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Not detected
Not detected
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,101
3
ENSG00000172794
RAB37
RAB37, member RAS oncogene family
[ "Q96AX2" ]
17
74670578-74747335
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
null
null
3
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 37: Neurons - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 61: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
0
0
0
[]
[]
[]
13,102
8
ENSG00000172795
DCP2
Decapping mRNA 2
[ "Q8IU60" ]
5
112976702-113022195
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB011677", "HPA057676" ]
[ "NUDT20" ]
[ "Enzymes", "Essential proteins", "Predicted intracellular proteins" ]
[ "Nonsense-mediated mRNA decay" ]
[ "Hydrolase", "RNA-binding" ]
[]
[ "Nucleoplasm", "Cytoplasmic bodies" ]
[ "Cell Junctions" ]
[]
[]
Approved
Approved
null
26
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 51: Lymphoid tissue - Adaptive immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,103
3
ENSG00000172803
SNX32
Sorting nexin 32
[ "Q86XE0" ]
11
65833834-65856896
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041775" ]
[ "FLJ30934", "SNX6B" ]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Cytosol" ]
[ "Focal adhesion sites" ]
[]
[]
Approved
Uncertain
null
14
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 51: Neurons - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in some
10
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
4
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,104
1
ENSG00000172817
CYP7B1
Cytochrome P450 family 7 subfamily B member 1
[ "O75881" ]
8
64587763-64798737
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017761" ]
[ "SPG5A" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins" ]
[ "Cholesterol metabolism", "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol metabolism" ]
[ "Monooxygenase", "Oxidoreductase" ]
[ "Disease variant", "Hereditary spastic paraplegia", "Intrahepatic cholestasis", "Neurodegeneration" ]
[]
[]
[]
[]
null
Uncertain
null
1
null
null
Cluster 46: Basophils - Proteolysis
Cluster 28: Oligodendrocytes - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 110: Mural cells - ECM organization
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
12
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,106
5
ENSG00000172819
RARG
Retinoic acid receptor gamma
[ "P13631" ]
12
53210567-53232980
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053883" ]
[ "NR1B3", "RAR-gamma", "RARC", "RARgamma" ]
[ "Cancer-related genes", "FDA approved drug targets", "Nuclear receptors", "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Receptor" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
12
null
null
Cluster 27: T-cells - Unknown function
Cluster 15: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
0
0
0
[]
[]
[]
13,108
8
ENSG00000172824
CES4A
Carboxylesterase 4A
[ "Q5XG92" ]
16
66988589-67010417
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA035701" ]
[ "CES8", "FLJ37464" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Serine esterase" ]
[]
[ "Cytosol" ]
[]
[ "Secreted - unknown location" ]
[ "Enzyme" ]
Approved
Approved
null
null
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 34: Non-specific - Mixed function
Cluster 50: Lymphoma - Unknown function
Cluster 4: Breast lactating luminal cells - Lactation
Cluster 2: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
13,109
4
ENSG00000172828
CES3
Carboxylesterase 3
[ "Q6UWW8" ]
16
66961245-66975149
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041008", "HPA041307" ]
[ "ES31", "FLJ21736" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Serine esterase" ]
[]
[ "Nuclear membrane", "Endoplasmic reticulum" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Approved
null
null
null
null
Cluster 19: Eosinophils - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,110
3
ENSG00000172830
SSH3
Slingshot protein phosphatase 3
[ "Q8TE77" ]
11
67303478-67312607
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019949", "HPA019957" ]
[ "FLJ10928", "FLJ20515" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nuclear speckles", "Cytosol" ]
[ "Plasma membrane", "Actin filaments" ]
[]
[]
Approved
Approved
null
3
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 30: White matter - Myelination
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
13,111
6
ENSG00000172831
CES2
Carboxylesterase 2
[ "O00748" ]
16
66934444-66945096
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018897", "HPA074629" ]
[ "CE-2", "CES2A1", "iCE" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid metabolism" ]
[ "Hydrolase", "Serine esterase" ]
[]
[ "Golgi apparatus" ]
[ "Endoplasmic reticulum", "Cytosol" ]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Enhanced
null
6
null
null
Cluster 33: Non-specific - ATP binding
Cluster 42: Choroid plexus - Mitochondria
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,112
1
ENSG00000172840
PDP2
Pyruvate dehydrogenase phosphatase catalytic subunit 2
[ "Q9P2J9" ]
16
66878589-66895754
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA019950", "HPA062059" ]
[ "KIAA1348", "PPM2B", "PPM2C2" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
1
null
null
Cluster 1: T-cells - Unknown function
Cluster 26: Oligodendrocytes - Mixed function
Cluster 68: Non-specific - Cell cycle regulation
Cluster 81: Alveolar cells - Lung function
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
13,113
9
ENSG00000172867
KRT2
Keratin 2
[ "P35908" ]
12
52644558-52652211
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006299", "CAB037321" ]
[ "KRT2A", "KRTE" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant", "FDA approved drug targets", "Ichthyosis" ]
[ "Intermediate filaments", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
34
null
null
Cluster 43: Non-specific - Transcription & Translation
null
Cluster 24: Non-specific - Unknown function
Cluster 26: Keratinocytes - Keratinization
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in many
57
Not detected
Not detected
null
Cancer enriched
Detected in some
7
Cell type enriched
Detected in some
49
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
13,115
5
ENSG00000172869
DMXL1
Dmx like 1
[ "Q9Y485" ]
5
119037772-119249138
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036431", "HPA036432" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoli", "Nucleoli fibrillar center" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
17
null
null
Cluster 32: Basophils - Transcription
Cluster 30: White matter - Myelination
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in all
4
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
13,116
2
ENSG00000172888
ZNF621
Zinc finger protein 621
[ "Q6ZSS3" ]
3
40524878-40574685
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA065518", "HPA071440" ]
[ "FLJ45246" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Enhanced
null
null
2
null
null
Cluster 30: Non-specific - DNA binding
Cluster 13: Oligodendrocytes - Mixed function
Cluster 8: Non-specific - Basic cellular processes
Cluster 7: Non-specific - Transcription
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Rectum Adenocarcinoma" ]
[ "Kidney Chromophobe", "Prostate Adenocarcinoma" ]
[ "Kidney Chromophobe", "Prostate Adenocarcinoma", "Rectum Adenocarcinoma" ]
13,118
5
ENSG00000172889
EGFL7
EGF like domain multiple 7
[ "Q9UHF1" ]
9
136658856-136672678
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA050716" ]
[ "ZNEU1" ]
[ "Predicted secreted proteins" ]
[ "Angiogenesis", "Cell adhesion", "Differentiation" ]
[ "Developmental protein" ]
[]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "Developmental protein" ]
null
Approved
null
12
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 47: Endothelial cells - Vasculature
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
6
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
13,119
2
ENSG00000172890
NADSYN1
NAD synthetase 1
[ "Q6IA69" ]
11
71453109-71524107
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017798", "HPA038523", "HPA038524" ]
[ "FLJ10631" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Ligase" ]
[ "Disease variant" ]
[ "Vesicles" ]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
Approved
Approved
null
14
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 24: Non-specific - Unknown function
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 5: Spleen - Immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
13,120
5
ENSG00000172893
DHCR7
7-dehydrocholesterol reductase
[ "Q9UBM7" ]
11
71428193-71452868
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044280" ]
[ "SLOS" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cholesterol biosynthesis", "Cholesterol metabolism", "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism" ]
[ "Hydrolase", "Oxidoreductase" ]
[ "Disease variant" ]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Supported
Approved
null
10
null
null
Cluster 24: Non-specific - Transcription
Cluster 49: Hindbrain - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,121
3
ENSG00000172901
LVRN
Laeverin
[ "Q6Q4G3" ]
5
115962454-116027619
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053254" ]
[ "APQ", "AQPEP", "FLJ90650", "TAQPEP" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
null
Cluster 31: Non-specific - Antiviral immune response
Cluster 89: Adipocytes - Lipid metabolism
Cluster 14: Adipose tissue - Angiogenesis
Group enriched
Detected in some
7
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
13,122
9
ENSG00000172915
NBEA
Neurobeachin
[ "Q8NFP9" ]
13
34942270-35673022
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039730", "HPA040385" ]
[ "BCL8B", "FLJ10197", "KIAA1544", "LYST2" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Golgi apparatus" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
5
null
null
Cluster 24: Non-specific - Transcription
Cluster 37: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in many
4
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
13,123
1
ENSG00000172922
RNASEH2C
Ribonuclease H2 subunit C
[ "Q8TDP1" ]
11
65714005-65720818
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA065375" ]
[ "AGS3", "AYP1" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Aicardi-Goutieres syndrome", "Disease variant" ]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Supported
null
14
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
13,124
4
ENSG00000172927
MYEOV
Myeloma overexpressed
[ "Q96EZ4" ]
11
69294151-69341682
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA012949" ]
[ "OCIM" ]
[ "Predicted membrane proteins" ]
[]
[]
[ "Proto-oncogene" ]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
Uncertain
null
11
null
null
null
null
Cluster 51: Myeloma - Immunoglobulins
Cluster 84: Apical squamous epithelium - Cornification
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in some
6
Not detected in immune cells
Not detected
null
3
0
3
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
13,125
1
ENSG00000172932
ANKRD13D
Ankyrin repeat domain 13D
[ "Q6ZTN6" ]
11
67289300-67302485
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039950" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
5
null
No
Cluster 5: Non-specific - Cell proliferation
Cluster 14: Neurons - Synaptic function
Cluster 24: Non-specific - Unknown function
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Breast Invasive Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
13,126
5
ENSG00000172935
MRGPRF
MAS related GPR family member F
[ "Q96AM1" ]
11
69004395-69013382
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA028811" ]
[ "GPR140", "GPR168", "MGC21621", "mrgF" ]
[ "G-protein coupled receptors", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[ "Vesicles", "Plasma membrane" ]
[ "Nucleoplasm", "Nuclear membrane", "Primary cilium transition zone" ]
[]
[]
Approved
Approved
null
null
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 64: Connective tissue cells - ECM organization
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
13,127
5
ENSG00000172936
MYD88
MYD88 innate immune signal transduction adaptor
[ "Q99836" ]
3
38138478-38143024
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009104" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Antiviral defense", "Immunity", "Inflammatory response", "Innate immunity" ]
[]
[ "Cancer-related genes", "Disease variant" ]
[ "Cytosol" ]
[ "Vesicles", "Mitochondria" ]
[]
[]
Supported
Approved
null
57
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 43: Hindbrain - Mixed function
Cluster 31: Non-specific - Antiviral immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 5: Spleen - Immune response
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Bladder Urothelial Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
13,128
6
ENSG00000172938
MRGPRD
MAS related GPR family member D
[ "Q8TDS7" ]
11
68980021-68980986
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at transcript level
[ "HPA031346" ]
[ "mrgD" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 59: Leukemia - T-cell receptor
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,129
9
ENSG00000172939
OXSR1
Oxidative stress responsive kinase 1
[ "O95747" ]
3
38165089-38255484
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008237", "CAB017181" ]
[ "KIAA1101", "OSR1" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Supported
null
58
null
null
Cluster 25: Non-specific - Unknown function
Cluster 50: Non-specific - Nucleic acid binding
Cluster 8: Non-specific - Basic cellular processes
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
13,130
3
ENSG00000172940
SLC22A13
Solute carrier family 22 member 13
[ "Q9Y226" ]
3
38265812-38278757
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035603", "HPA035962" ]
[ "OAT10", "OCTL1", "OCTL3", "ORCTL3" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 72: Kidney - Transmembrane transport
Tissue enriched
Detected in single
29
Not detected
Not detected
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,131
6
ENSG00000172943
PHF8
PHD finger protein 8
[ "Q9UPP1" ]
X
53936676-54048958
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038779", "HPA062015" ]
[ "JHDM1F", "KDM7B", "KIAA1111", "ZNF422" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Cell cycle", "Transcription", "Transcription regulation" ]
[ "Activator", "Chromatin regulator", "Dioxygenase", "Oxidoreductase" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
26
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 50: Non-specific - Nucleic acid binding
Cluster 10: Ciliated cells - Ion channel activity
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
13,132
8
ENSG00000172954
LCLAT1
Lysocardiolipin acyltransferase 1
[ "Q6UWP7" ]
2
30447226-30644225
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031880", "HPA049217" ]
[ "AGPAT8", "ALCAT1", "FLJ37965", "LPLAT6", "LYCAT" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[ "Lipid biosynthesis", "Lipid metabolism", "Phospholipid biosynthesis", "Phospholipid metabolism" ]
[ "Acyltransferase", "Developmental protein", "Transferase" ]
[]
[ "Endoplasmic reticulum" ]
[ "Cytosol" ]
[]
[]
Supported
Uncertain
null
10
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 9: Non-specific - Receptor signaling
Cluster 32: Non-specific - Cell proliferation
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 35: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
13,133
7
ENSG00000172955
ADH6
Alcohol dehydrogenase 6 (class V)
[ "P28332" ]
4
99202638-99219537
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA067946", "HPA069081" ]
[ "ADH-5" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Oxidoreductase" ]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
null
Cluster 18: Liver cancer - Metabolism
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
13
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
17
Cell type enriched
Detected in some
11
Not detected in immune cells
Not detected
null
2
0
2
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
13,134
9
ENSG00000172977
KAT5
Lysine acetyltransferase 5
[ "Q92993" ]
11
65711996-65719604
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016953", "HPA074328" ]
[ "cPLA2", "ESA1", "HTATIP", "HTATIP1", "PLIP", "TIP60", "ZC2HC5" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Transcription factors" ]
[ "DNA damage", "DNA repair", "Growth regulation", "Host-virus interaction", "Immunity", "Innate immunity", "Transcription", "Transcription regulation" ]
[ "Activator", "Acyltransferase", "Chromatin regulator", "Transferase" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Supported
Approved
null
288
null
null
Cluster 25: Non-specific - Unknown function
Cluster 26: Oligodendrocytes - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
13,137
7
ENSG00000172985
SH3RF3
SH3 domain containing ring finger 3
[ "Q8TEJ3" ]
2
109129205-109504634
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044822", "HPA048444" ]
[ "FLJ00204", "POSH2", "SH3MD4" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
8
Yes
No
null
Cluster 51: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
13,138
4
ENSG00000172986
GXYLT2
Glucoside xylosyltransferase 2
[ "A0PJZ3" ]
3
72888046-72998138
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA068429" ]
[ "GLT8D4" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Cytokinetic bridge", "Midbody ring" ]
[]
[]
Approved
Uncertain
null
null
Yes
No
Cluster 2: Dendritic cells - Unknown function
Cluster 13: Oligodendrocytes - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 108: Fibroblasts - ECM organization
Cluster 35: Non-specific - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Stomach Adenocarcinoma" ]
[ "Stomach Adenocarcinoma" ]
13,139
7
ENSG00000172987
HPSE2
Heparanase 2 (inactive)
[ "Q8WWQ2" ]
10
98457077-99235862
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044603" ]
[ "HPA2", "HPR2", "UFS" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
null
Uncertain
null
null
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
9
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
13,140
6
ENSG00000172992
DCAKD
Dephospho-CoA kinase domain containing
[ "Q8WVC6" ]
17
45023338-45061131
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA060997" ]
[ "FLJ22955" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
16
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 44: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 73: Brain - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
13,141
5
ENSG00000172995
ARPP21
CAMP regulated phosphoprotein 21
[ "Q9UBL0" ]
3
35638945-35794496
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017303" ]
[ "ARPP-21", "R3HDM3", "TARPP" ]
[ "Predicted intracellular proteins" ]
[]
[ "Calmodulin-binding" ]
[]
[ "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
Supported
null
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 33: Neurons - Mixed function
Cluster 35: RS4;11 - Unknown function
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in many
5
Cancer enriched
Detected in some
8
Cancer enriched
Detected in some
7
Cell type enhanced
Detected in some
null
Immune cell enriched
Detected in single
30
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
13,142
7
ENSG00000173011
TADA2B
Transcriptional adaptor 2B
[ "Q86TJ2" ]
4
7041899-7057952
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035770" ]
[ "MGC21874" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Approved
Approved
null
62
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 32: Cerebral cortex - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
2
2
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
13,143
8
ENSG00000173013
CCDC96
Coiled-coil domain containing 96
[ "Q2M329" ]
4
7040849-7043001
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047546" ]
[ "FLJ90575" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
4
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 17: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Tissue enriched
Detected in many
5
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Not detected
Not detected
null
Immune cell enhanced
Detected in some
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
13,144
2
ENSG00000173020
GRK2
G protein-coupled receptor kinase 2
[ "P25098" ]
11
67266473-67286556
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005021", "CAB037248", "HPA060707" ]
[ "ADRBK1", "BARK1" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Vesicles" ]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
Approved
Enhanced
null
39
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 32: Cerebral cortex - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
13,145
3
ENSG00000173039
RELA
RELA proto-oncogene, NF-kB subunit
[ "Q04206" ]
11
65653599-65663090
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004264", "CAB005030", "HPA063461" ]
[ "NFKB3", "p65" ]
[ "Cancer-related genes", "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins", "RAS pathway related proteins", "Transcription factors" ]
[ "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Cancer-related genes", "Disease variant" ]
[ "Cytosol" ]
[]
[]
[]
Enhanced
Supported
null
281
null
null
Cluster 1: T-cells - Unknown function
Cluster 6: Non-specific - Immune response
Cluster 24: Non-specific - Unknown function
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
13,146
4
ENSG00000173040
EVC2
EvC ciliary complex subunit 2
[ "Q86UK5" ]
4
5542772-5709548
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040910", "HPA048122" ]
[ "LBN" ]
[ "Disease related genes", "Human disease related genes", "Predicted membrane proteins" ]
[]
[]
[ "Ciliopathy", "Disease variant", "Dwarfism", "Ectodermal dysplasia" ]
[ "Plasma membrane", "Microtubules", "Cytokinetic bridge", "Primary cilium" ]
[ "Nucleoplasm", "Primary cilium tip", "Basal body", "Cytosol" ]
[]
[]
Approved
Uncertain
null
null
Yes
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
13,147
8
ENSG00000173041
ZNF680
Zinc finger protein 680
[ "Q8NEM1" ]
7
64519878-64563075
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003173" ]
[ "FLJ90430" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
null
null
null
Cluster 24: Non-specific - Transcription
Cluster 28: Oligodendrocytes - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 55: Myocytes - Oxidative muscle function
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
13,148
3
ENSG00000173064
HECTD4
HECT domain E3 ubiquitin protein ligase 4
[]
12
112160188-112382439
Evidence at transcript level
Evidence at transcript level
null
null
[ "HPA041062", "HPA045473" ]
[ "C12orf51", "FLJ34154", "KIAA0614" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nuclear speckles", "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 32: Basophils - Transcription
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 38: Non-specific - Transcription
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 27: Cerebellum - Synaptic function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in all
null
Not detected in immune cells
Not detected
null
4
2
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
13,149
3
ENSG00000173065
FAM222B
Family with sequence similarity 222 member B
[ "Q8WU58" ]
17
28755980-28855232
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051840", "HPA062239" ]
[ "C17orf63", "FLJ10700" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Approved
null
28
null
null
Cluster 22: Eosinophils - Transcription
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 27: Breast cancer - Unknown function
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
13,150
3