ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000109851
DBX1
Developing brain homeobox 1
[ "A6NMT0" ]
11
20156155-20160475
Evidence at protein level
No human protein/transcript evidence
No human protein/transcript evidence
Evidence at protein level
[ "HPA039802" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "Developmental protein", "DNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
Cluster 33: Sarcoma - Muscle contraction
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
null
Not detected
Not detected
null
Group enriched
Detected in some
16
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
3,671
9
ENSG00000109854
HTATIP2
HIV-1 Tat interactive protein 2
[ "Q9BUP3" ]
11
20363685-20383782
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006417", "HPA024321" ]
[ "CC3", "FLJ26963", "SDR44U1", "TIP30" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Host-virus interaction", "Translation regulation" ]
[]
[ "Tumor suppressor" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
6
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
3,672
2
ENSG00000109861
CTSC
Cathepsin C
[ "P53634" ]
11
88265069-88359684
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025364", "HPA066610", "HPA068434" ]
[ "DPP1", "PALS", "PLS" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase", "Protease", "Thiol protease" ]
[ "Disease variant", "Palmoplantar keratoderma" ]
[ "Vesicles" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Supported
Enhanced
null
9
No
No
Cluster 10: Non-specific - Membrane trafficking
Cluster 20: Macrophages & Microglia - Immune response
Cluster 64: Connective tissue cells - ECM organization
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Bladder Urothelial Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Liver Hepatocellular Carcinoma" ]
3,673
6
ENSG00000109881
CCDC34
Coiled-coil domain containing 34
[ "Q96HJ3" ]
11
27330827-27363234
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037574" ]
[ "L15", "NY-REN-41", "RAMA3" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nuclear membrane", "Nucleoli fibrillar center", "Calyx", "Mid piece" ]
[ "Connecting piece", "Principal piece", "End piece" ]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 24: Neurons - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 27: Non-specific - Cell proliferation
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
2
3
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
3,674
6
ENSG00000109911
ELP4
Elongator acetyltransferase complex subunit 4
[ "Q96EB1" ]
11
31509755-31790324
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038572", "HPA038573" ]
[ "C11orf19", "PAXNEB" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[ "tRNA processing" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
8
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 15: Non-specific - Transcription
Cluster 30: Non-specific - Gene expression regulation
Cluster 7: Non-specific - Transcription
Cluster 27: Cerebellum - Synaptic function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Lung Squamous Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
3,676
1
ENSG00000109917
ZPR1
ZPR1 zinc finger
[ "O75312" ]
11
116773799-116788039
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB022596", "HPA030979" ]
[ "ZNF259" ]
[ "Disease related genes", "Essential proteins", "Predicted intracellular proteins" ]
[ "Differentiation", "mRNA processing", "mRNA splicing" ]
[]
[ "Deafness", "Dwarfism", "Hypotrichosis" ]
[ "Vesicles" ]
[]
[]
[]
Approved
Uncertain
null
2
null
null
Cluster 25: Non-specific - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 24: Non-specific - Unknown function
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in all
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
3,677
5
ENSG00000109919
MTCH2
Mitochondrial carrier 2
[ "Q9Y6C9" ]
11
47617315-47642607
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038390" ]
[ "SLC25A50" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
81
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 21: Non-specific - Metabolism
Cluster 24: Non-specific - Unknown function
Cluster 97: Non-specific - Cellular respiration
Cluster 31: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
3,678
6
ENSG00000109920
FNBP4
Formin binding protein 4
[ "Q8N3X1" ]
11
47716494-47767443
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039485", "HPA040029" ]
[ "KIAA1014" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
3
null
null
Cluster 22: Eosinophils - Transcription
Cluster 48: Non-specific - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 102: Non-specific - Mixed function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
3,679
3
ENSG00000109927
TECTA
Tectorin alpha
[ "O75443" ]
11
121101243-121191490
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA018870" ]
[ "DFNA12", "DFNA8", "DFNB21" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Predicted secreted proteins", "Transporters" ]
[ "Hearing" ]
[]
[ "Deafness", "Disease variant", "Non-syndromic deafness" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Other" ]
null
Approved
null
null
null
null
null
Cluster 1: Neurons - Mixed function
Cluster 54: Non-specific - Transcription
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in some
null
Cancer enriched
Detected in single
4
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
3,680
6
ENSG00000109929
SC5D
Sterol-C5-desaturase
[ "O75845" ]
11
121292681-121313410
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA066283", "HPA070248" ]
[ "SC5DL" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins" ]
[ "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism" ]
[ "Oxidoreductase" ]
[ "Disease variant" ]
[ "Nucleoplasm", "Endoplasmic reticulum" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
Approved
Enhanced
null
2
No
No
Cluster 30: Non-specific - DNA binding
Cluster 49: Hindbrain - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Skin Cutaneous Melanoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Skin Cutaneous Melanoma" ]
3,681
6
ENSG00000109943
CRTAM
Cytotoxic and regulatory T cell molecule
[ "O95727" ]
11
122838500-122872643
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CD355" ]
[ "CD markers", "Predicted membrane proteins" ]
[ "Adaptive immunity", "Cell adhesion", "Immunity" ]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 24: Non-specific - Transcription
Cluster 35: Non-specific - DNA binding
Cluster 59: Leukemia - T-cell receptor
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 71: Cerebellum - Nervous system development
Tissue enriched
Detected in some
16
Not detected
Not detected
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in many
null
1
0
1
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
3,682
9
ENSG00000109971
HSPA8
Heat shock protein family A (Hsp70) member 8
[ "P11142" ]
11
123057489-123063230
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002056", "HPA052504" ]
[ "HSC70", "HSC71", "HSP73", "HSPA10" ]
[ "Cancer-related genes", "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Autophagy", "Host-virus interaction", "mRNA processing", "mRNA splicing", "Stress response", "Transcription", "Transcription regulation" ]
[ "Chaperone", "Hydrolase", "Repressor" ]
[ "Cancer-related genes" ]
[ "Vesicles", "Flagellar centriole", "Annulus" ]
[ "Perinuclear theca", "Calyx" ]
[]
[]
Supported
Uncertain
null
697
null
Yes
Cluster 9: T-regs - Cell cycle regulation
Cluster 21: Non-specific - Metabolism
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 20: Non-specific - Transcription regulation
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
3,685
8
ENSG00000109991
P2RX3
Purinergic receptor P2X 3
[ "P56373" ]
11
57338352-57372396
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA057776" ]
[ "P2X3" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[ "Ion channel", "Ligand-gated ion channel", "Receptor" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
Cluster 65: Non-specific - Unknown function
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 35: Non-specific - Mixed function
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in some
5
Not detected
Not detected
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
3,686
2
ENSG00000110002
VWA5A
Von Willebrand factor A domain containing 5A
[ "O00534" ]
11
124115404-124147721
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037813", "HPA037814", "HPA061500" ]
[ "BCSC-1", "LOH11CR2A" ]
[ "Predicted intracellular proteins" ]
[]
[]
[ "Tumor suppressor" ]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Enhanced
Uncertain
null
3
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 77: Intestine - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
6
Immune cell enriched
Detected in many
5
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
3,687
8
ENSG00000110011
DNAJC4
DnaJ heat shock protein family (Hsp40) member C4
[ "Q9NNZ3" ]
11
64230278-64234286
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA011947" ]
[ "HSPF2", "MCG18" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Chaperone" ]
[]
[]
[]
[]
[]
null
Uncertain
null
5
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 18: Non-specific - Mixed function
Cluster 35: RS4;11 - Unknown function
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 21: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
8
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
3,688
4
ENSG00000110013
SIAE
Sialic acid acetylesterase
[ "Q9HAT2" ]
11
124633113-124695707
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038052", "HPA038053" ]
[ "CSE-C", "LSE", "MGC87009", "YSG2" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Serine esterase" ]
[ "Disease variant" ]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Approved
null
2
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 44: Non-specific - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
3,689
5
ENSG00000110025
SNX15
Sorting nexin 15
[ "Q9NRS6" ]
11
65027439-65040572
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038955" ]
[]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Nucleoli", "Cytosol" ]
[ "Vesicles", "Plasma membrane" ]
[]
[]
Approved
Approved
null
8
null
null
Cluster 25: Non-specific - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
3,690
7
ENSG00000110031
LPXN
Leupaxin
[ "O60711" ]
11
58526871-58578220
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043741", "CAB046478", "HPA061441" ]
[ "LDPL" ]
[ "Predicted intracellular proteins" ]
[ "Cell adhesion", "Transcription", "Transcription regulation" ]
[ "Activator" ]
[]
[ "Focal adhesion sites" ]
[ "Nuclear speckles", "Cytosol" ]
[]
[]
Supported
Enhanced
null
20
No
No
Cluster 13: Non-specific - Mitochondria
Cluster 28: Oligodendrocytes - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 51: Lymphoid tissue - Adaptive immune response
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
3,691
6
ENSG00000110042
DTX4
Deltex E3 ubiquitin ligase 4
[ "Q9Y2E6" ]
11
59171430-59208588
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA056760", "HPA059294" ]
[ "KIAA0937", "RNF155" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Notch signaling pathway", "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
2
null
null
Cluster 29: Non-specific - Unknown function
Cluster 30: White matter - Myelination
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
0
2
[ "Rectum Adenocarcinoma", "Thyroid Carcinoma" ]
[]
[ "Rectum Adenocarcinoma", "Thyroid Carcinoma" ]
3,692
8
ENSG00000110046
ATG2A
Autophagy related 2A
[ "Q2TAZ0" ]
11
64894546-64917211
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038715" ]
[ "BLTP4A", "KIAA0404" ]
[ "Predicted intracellular proteins", "Transporters" ]
[ "Autophagy", "Lipid transport", "Transport" ]
[]
[]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Uncertain
Uncertain
null
9
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 12: Non-specific - Vasculature
Cluster 24: Non-specific - Unknown function
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
6
2
0
2
[ "Breast Invasive Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Rectum Adenocarcinoma" ]
3,693
2
ENSG00000110047
EHD1
EH domain containing 1
[ "Q9H4M9" ]
11
64851642-64888296
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049890", "HPA049986", "HPA066751", "HPA067747" ]
[ "FLJ42622", "FLJ44618", "H-PAST", "HPAST1", "PAST1" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Cilium biogenesis/degradation", "Protein transport", "Transport" ]
[]
[]
[ "Plasma membrane" ]
[ "Primary cilium", "Primary cilium transition zone" ]
[]
[]
Supported
Approved
null
46
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 25: Non-specific - Transcription
Cluster 55: Lymphoma - Immune response
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 39: Testis - Nuclear processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
5
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
3,694
1
ENSG00000110048
OSBP
Oxysterol binding protein
[ "P22059" ]
11
59574398-59615774
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039227", "HPA043625" ]
[ "OSBP1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Lipid transport", "Transport" ]
[]
[]
[ "Golgi apparatus" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Supported
Enhanced
null
41
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 21: Non-specific - Metabolism
Cluster 24: Non-specific - Unknown function
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
3,695
6
ENSG00000110057
UNC93B1
Unc-93 homolog B1, TLR signaling regulator
[ "Q9H1C4" ]
11
67991100-68004982
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038716", "HPA038717", "HPA042803" ]
[ "UNC93" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Adaptive immunity", "Antiviral defense", "Immunity", "Innate immunity" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
111
No
No
Cluster 29: Non-specific - Unknown function
Cluster 43: Hindbrain - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response
Cluster 5: Spleen - Immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
0
3
[]
[ "Breast Invasive Carcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
3,696
1
ENSG00000110060
PUS3
Pseudouridine synthase 3
[ "Q9BZE2" ]
11
125893485-125903221
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038040", "HPA063802" ]
[ "DEG1", "FKSG32" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "tRNA processing" ]
[ "Isomerase" ]
[ "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 31: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 17: Non-specific - RNA processing
Cluster 45: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
3,697
8
ENSG00000110063
DCPS
Decapping enzyme, scavenger
[ "Q96C86" ]
11
126304060-126350005
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039632", "HPA058597" ]
[ "HINT-5", "HINT5", "HSL1", "HSPC015" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "Hydrolase" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
10
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 23: Choroid plexus - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 44: Plasma cells - Antibody production & secretion
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
3,698
2
ENSG00000110066
KMT5B
Lysine methyltransferase 5B
[ "Q4FZB7" ]
11
68154863-68213852
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038509" ]
[ "CGI-85", "SUV420H1" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Myogenesis", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Methyltransferase", "Repressor", "Transferase" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm", "Nucleoli fibrillar center" ]
[ "Plasma membrane", "Microtubules", "Cytokinetic bridge", "Mitotic spindle", "Primary cilium", "Centrosome", "Basal body", "Cytoplasmic bodies" ]
[]
[]
Supported
null
null
4
Yes
null
Cluster 45: Eosinophils - Unknown function
Cluster 55: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
3,699
8
ENSG00000110074
FOXRED1
FAD dependent oxidoreductase domain containing 1
[ "Q96CU9" ]
11
126269024-126278131
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039620", "HPA046192" ]
[ "H17" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[ "Oxidoreductase" ]
[ "Disease variant", "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Uncertain
null
4
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 24: Non-specific - Unknown function
Cluster 65: Non-specific - Cell growth & division
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
3,700
7
ENSG00000110075
PPP6R3
Protein phosphatase 6 regulatory subunit 3
[ "Q5H9R7" ]
11
68460731-68615334
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017183", "HPA038467", "HPA038468" ]
[ "C11orf23", "DKFZp781E17107", "DKFZp781E2374", "DKFZp781O2362", "FLJ11058", "FLJ43065", "KIAA1558", "MGC125711", "MGC125712", "PP6R3", "SAP190", "SAPL", "SAPLa", "SAPS3" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Plasma membrane", "Cytosol" ]
[]
[]
[]
Enhanced
Supported
null
30
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 55: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
5
0
5
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Uterine Corpus Endometrial Carcinoma" ]
3,701
7
ENSG00000110076
NRXN2
Neurexin 2
[ "P58401", "Q9P2S2" ]
11
64606174-64723197
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 109: Neurons - Neuronal signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enriched
Detected in many
8
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
3,702
1
ENSG00000110077
MS4A6A
Membrane spanning 4-domains A6A
[ "Q9H2W1" ]
11
60172015-60184666
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA011391", "HPA076623" ]
[ "CD20L3", "MS4A6" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
1
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in all
null
Cancer enriched
Detected in some
8
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in all
8
0
0
0
[]
[]
[]
3,703
5
ENSG00000110079
MS4A4A
Membrane spanning 4-domains A4A
[ "Q96JQ5" ]
11
60185657-60318080
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029323" ]
[ "CD20L1", "MS4A4", "MS4A7" ]
[ "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
Approved
null
14
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 20: Macrophages & Microglia - Immune response
Cluster 47: Leukemia - Hemostasis
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
5
1
0
1
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
3,704
3
ENSG00000110080
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
[ "Q11206" ]
11
126355640-126440344
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049827" ]
[ "CGS23", "FLJ11867", "NANTA3", "SAT3", "SIAT4", "SIAT4C", "STZ" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[ "Glycosyltransferase", "Transferase" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Approved
null
null
null
null
Cluster 41: Basophils - Unknown function
Cluster 30: White matter - Myelination
Cluster 69: Skin cancer - ECM organization
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Cancer enriched
Detected in all
4
Cancer enhanced
Detected in all
null
Group enriched
Detected in many
4
Group enriched
Detected in many
4
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
3,705
2
ENSG00000110090
CPT1A
Carnitine palmitoyltransferase 1A
[ "P50416" ]
11
68754620-68844410
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008835" ]
[ "CPT1", "CPT1-L", "L-CPT1" ]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Fatty acid metabolism", "Lipid metabolism", "Transport" ]
[ "Acyltransferase", "Transferase" ]
[ "Disease variant", "FDA approved drug targets" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Supported
null
12
null
null
Cluster 41: Basophils - Unknown function
Cluster 42: Choroid plexus - Mitochondria
Cluster 7: Liver cancer - Metabolism
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 77: Intestine - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
3,706
4
ENSG00000110092
CCND1
Cyclin D1
[ "P24385" ]
11
69641156-69654474
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA027802", "CAB080462" ]
[ "BCL1", "D11S287E", "PRAD1", "U21B31" ]
[ "Cancer-related genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "Transporters" ]
[ "Cell cycle", "Cell division", "DNA damage", "Transcription", "Transcription regulation" ]
[ "Cyclin", "Repressor" ]
[ "Cancer-related genes", "FDA approved drug targets", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Supported
null
98
Yes
No
Cluster 32: Basophils - Transcription
Cluster 42: Choroid plexus - Mitochondria
Cluster 64: Connective tissue cells - ECM organization
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 58: Skin - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
3,707
6
ENSG00000110104
CCDC86
Coiled-coil domain containing 86
[ "Q9H6F5" ]
11
60842113-60851081
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041117", "HPA041540" ]
[ "cyclon", "MGC2574" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[]
[]
[ "Nucleoli", "Nucleoli rim", "Mitotic chromosome" ]
[ "Nucleoplasm" ]
[]
[]
Enhanced
Enhanced
null
22
Yes
No
Cluster 13: Non-specific - Mitochondria
Cluster 27: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 69: Parathyroid gland - Mixed function
Tissue enriched
Detected in all
8
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
4
1
[]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
3,708
2
ENSG00000110107
PRPF19
Pre-mRNA processing factor 19
[ "Q9UMS4" ]
11
60890547-60906585
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB012448", "HPA038051", "HPA059070" ]
[ "hPSO4", "NMP200", "PRP19", "PSO4", "SNEV", "UBOX4" ]
[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "mRNA processing", "mRNA splicing", "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Enhanced
Supported
null
197
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 1: Neurons - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 2: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
3,709
6
ENSG00000110108
TMEM109
Transmembrane protein 109
[ "Q9BVC6" ]
11
60914158-60923443
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011785", "HPA012101" ]
[ "MGC5508" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[ "Ion channel", "Voltage-gated channel" ]
[]
[ "Nuclear membrane", "Endoplasmic reticulum" ]
[ "Vesicles", "Actin filaments" ]
[]
[]
Approved
Approved
null
18
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 42: Choroid plexus - Mitochondria
Cluster 24: Non-specific - Unknown function
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
3,710
8
ENSG00000110148
CCKBR
Cholecystokinin B receptor
[ "P32239" ]
11
6259806-6272127
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA079548" ]
[]
[ "Cancer-related genes", "FDA approved drug targets", "G-protein coupled receptors", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Vesicles" ]
[ "Plasma membrane" ]
[]
[]
Uncertain
null
null
7
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 34: Testis cancer - Unknown function
Cluster 97: Non-specific - Cellular respiration
Cluster 70: Non-specific - Protein processing
Group enriched
Detected in some
33
Group enriched
Detected in some
6
Cancer enriched
Detected in some
9
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
3,711
8
ENSG00000110169
HPX
Hemopexin
[ "P02790" ]
11
6431049-6442617
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB016725", "HPA065318", "HPA068847" ]
[]
[ "Candidate cardiovascular disease genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Host-virus interaction", "Transport" ]
[]
[]
[]
[]
[ "Secreted to blood" ]
[ "Transport" ]
null
Approved
null
13
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 18: Liver cancer - Metabolism
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in many
792
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
69
Cell type enriched
Detected in many
82
Not detected in immune cells
Not detected
null
3
2
2
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
3,712
7
ENSG00000110171
TRIM3
Tripartite motif containing 3
[ "O75382" ]
11
6448613-6474459
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043396", "HPA048233" ]
[ "BERP", "HAC1", "RNF22", "RNF97" ]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[ "Transferase" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Enhanced
null
30
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 65: Non-specific - Cell growth & division
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
3,713
3
ENSG00000110172
CHORDC1
Cysteine and histidine rich domain containing 1
[ "Q9UHD1" ]
11
90200429-90223077
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041040" ]
[ "CHP-1", "CHP1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Stress response" ]
[ "Chaperone" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
21
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 102: Non-specific - Mixed function
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
2
3
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
3,714
1
ENSG00000110195
FOLR1
Folate receptor alpha
[ "P15328" ]
11
72189558-72196323
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FOLR", "FRalpha" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Predicted membrane proteins", "Predicted secreted proteins", "Transporters" ]
[ "Transport" ]
[ "Receptor" ]
[ "FDA approved drug targets", "Neurodegeneration" ]
[]
[]
[ "Secreted to blood" ]
[ "Receptor" ]
null
null
null
4
null
null
null
Cluster 36: Choroid plexus - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 4: Breast lactating luminal cells - Lactation
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enriched
Detected in many
14
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
3,715
9
ENSG00000110200
ANAPC15
Anaphase promoting complex subunit 15
[ "P60006" ]
11
72106378-72112780
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036596" ]
[ "APC15", "C11orf51", "DKFZP564M082", "HSPC020" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis" ]
[]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
Approved
null
20
null
null
Cluster 29: Non-specific - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
3,716
9
ENSG00000110203
FOLR3
Folate receptor gamma
[ "P41439" ]
11
72114869-72139892
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FR-G", "FRgamma" ]
[ "Metabolic proteins", "Predicted secreted proteins" ]
[]
[ "Receptor" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Receptor" ]
null
null
null
1
null
null
Cluster 21: Neutrophils - Unknown function
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 15: Bone marrow - Innate immune response
Group enriched
Detected in some
10
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
11
0
0
0
[]
[]
[]
3,717
9
ENSG00000110237
ARHGEF17
Rho guanine nucleotide exchange factor 17
[ "Q96PE2" ]
11
73308276-73369388
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA007991", "HPA074658" ]
[ "KIAA0337", "p164-RhoGEF", "TEM4" ]
[ "Predicted intracellular proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[]
[ "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Approved
Uncertain
null
10
null
null
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 110: Mural cells - ECM organization
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
3,719
7
ENSG00000110243
APOA5
Apolipoprotein A5
[ "Q6Q788" ]
11
116789367-116792420
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "APOA-V", "RAP3" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Lipid transport", "Transport" ]
[]
[ "Disease variant" ]
[]
[]
[ "Secreted to blood" ]
[ "Apolipoprotein" ]
null
null
null
12
null
null
null
null
Cluster 18: Liver cancer - Metabolism
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 31: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
227
Cancer enriched
Detected in single
18
Cancer enriched
Detected in single
309
Cell type enriched
Detected in some
387
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
3,720
5
ENSG00000110244
APOA4
Apolipoprotein A4
[ "P06727" ]
11
116820700-116823304
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001352", "HPA002549", "CAB068250", "CAB068251", "CAB068252" ]
[]
[ "Candidate cardiovascular disease genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Lipid transport", "Transport" ]
[]
[ "Amyloidosis", "Disease variant" ]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Apolipoprotein" ]
Approved
Enhanced
null
7
null
null
null
null
Cluster 34: Testis cancer - Unknown function
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in some
12
Cancer enriched
Detected in single
7
Cancer enriched
Detected in some
24
Cell type enriched
Detected in some
65
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
3,721
3
ENSG00000110245
APOC3
Apolipoprotein C3
[ "P02656" ]
11
116829706-116833072
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA065365", "HPA073918" ]
[ "Apo-C3", "Apo-CIII", "ApoC-3", "ApoC-III", "APOCIII" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted secreted proteins" ]
[ "Lipid degradation", "Lipid metabolism", "Lipid transport", "Transport" ]
[]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets" ]
[ "Nucleoplasm" ]
[ "Nucleoli", "Cell Junctions" ]
[ "Secreted to blood" ]
[ "Apolipoprotein" ]
Approved
Supported
null
8
null
null
null
null
Cluster 18: Liver cancer - Metabolism
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in many
25
Cancer enriched
Detected in some
4
Cancer enriched
Detected in many
453
Cell type enriched
Detected in some
9
Not detected in immune cells
Not detected
null
1
2
0
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
3,722
4
ENSG00000110274
CEP164
Centrosomal protein 164
[ "Q9UPV0" ]
11
117314557-117413266
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA037605", "HPA037606", "HPA061504" ]
[ "KIAA1052", "NPHP15" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Cilium biogenesis/degradation", "DNA damage", "DNA repair", "Mitosis" ]
[]
[ "Ciliopathy", "Disease variant", "Nephronophthisis" ]
[ "Primary cilium transition zone", "Centrosome", "Principal piece" ]
[ "Nucleoplasm", "Vesicles", "Equatorial segment" ]
[]
[]
Approved
Uncertain
null
17
null
null
Cluster 32: Basophils - Transcription
Cluster 6: Non-specific - Immune response
Cluster 24: Non-specific - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 8: Pancreas - Proteolysis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
3,723
4
ENSG00000110318
CEP126
Centrosomal protein 126
[ "Q9P2H0" ]
11
101915010-102001062
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "KIAA1377" ]
[ "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[]
[]
[]
[]
[]
[]
null
null
null
17
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 11: Neuronal - Sensory perception
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
3,725
2
ENSG00000110321
EIF4G2
Eukaryotic translation initiation factor 4 gamma 2
[ "P78344" ]
11
10797050-10808940
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005163", "HPA006773", "HPA016965" ]
[ "DAP5", "NAT1", "p97" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Protein biosynthesis", "Translation regulation" ]
[ "Initiation factor", "Repressor" ]
[]
[ "Cytosol" ]
[]
[]
[]
Enhanced
Approved
null
27
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 44: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
3,726
5
ENSG00000110324
IL10RA
Interleukin 10 receptor subunit alpha
[ "Q13651" ]
11
117986370-118003037
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA065647", "HPA069086" ]
[ "CD210", "CD210a", "CDW210A", "HIL-10R", "IL10R" ]
[ "CD markers", "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[]
[ "Receptor" ]
[ "Disease variant" ]
[ "Plasma membrane", "Cytosol" ]
[ "Primary cilium" ]
[]
[]
Supported
null
null
30
null
null
Cluster 33: Non-specific - ATP binding
Cluster 22: Non-specific - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
3,727
2
ENSG00000110328
GALNT18
Polypeptide N-acetylgalactosaminyltransferase 18
[ "Q6P9A2" ]
11
11270877-11622005
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA012955", "HPA070681" ]
[ "GalNAc-T18", "GALNT15", "GALNTL4", "MGC71806" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Golgi apparatus" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Approved
Approved
null
27
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
3,728
5
ENSG00000110330
BIRC2
Baculoviral IAP repeat containing 2
[ "Q13490" ]
11
102347211-102378670
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005513", "CAB020661" ]
[ "API1", "c-IAP1", "cIAP1", "hiap-2", "MIHB", "RNF48" ]
[ "Cancer-related genes", "Enzymes", "Predicted intracellular proteins" ]
[ "Apoptosis", "Transcription", "Transcription regulation", "Ubl conjugation pathway" ]
[ "Activator", "Transferase" ]
[ "Cancer-related genes" ]
[ "Nucleoli fibrillar center", "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Supported
null
131
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 55: Non-specific - Transcription
Cluster 72: Neuronal - Signal transduction
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 51: Lymphoid tissue - Adaptive immune response
Low tissue specificity
Detected in all
null
Cancer enriched
Detected in all
4
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
3,729
8
ENSG00000110367
DDX6
DEAD-box helicase 6
[ "P26196" ]
11
118747763-118791164
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004668", "HPA024201", "HPA026644" ]
[ "HLR2", "RCK", "Rck/p54" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Helicase", "Hydrolase", "RNA-binding" ]
[ "Cancer-related genes", "Disease variant", "Intellectual disability", "Proto-oncogene" ]
[ "Cytoplasmic bodies" ]
[ "Plasma membrane", "Midbody", "Cytosol" ]
[]
[]
Supported
Approved
null
307
Yes
null
Cluster 21: Neutrophils - Unknown function
Cluster 31: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
3,731
1
ENSG00000110375
UPK2
Uroplakin 2
[ "O00526" ]
11
118925164-118958559
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043312", "HPA061106" ]
[ "MGC138598", "UP2", "UPII" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
71
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 11: Esophagus - Basic cellular processes
Tissue enriched
Detected in some
25
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
63
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
3,732
6
ENSG00000110395
CBL
Cbl proto-oncogene
[ "P22681" ]
11
119206298-119313926
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004350", "HPA027956" ]
[ "c-Cbl", "CBL2", "RNF55" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[ "Cancer-related genes", "Disease variant", "Proto-oncogene" ]
[ "Cytosol" ]
[ "Mitotic spindle", "End piece" ]
[]
[]
Supported
Enhanced
null
201
Yes
null
Cluster 7: Non-specific - Innate immune response
Cluster 19: Astrocytes - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 51: Lymphoid tissue - Adaptive immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
3,733
6
ENSG00000110400
NECTIN1
Nectin cell adhesion molecule 1
[ "Q15223" ]
11
119623408-119729200
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB016135", "HPA026846" ]
[ "CD111", "CLPED1", "ED4", "HIgR", "HVEC", "Nectin-1", "OFC7", "PRR", "PRR1", "PVRL1", "PVRR1", "SK-12" ]
[ "CD markers", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted membrane proteins", "Predicted secreted proteins" ]
[ "Cell adhesion", "Host-virus interaction" ]
[ "Host cell receptor for virus entry", "Receptor" ]
[ "Disease variant", "Ectodermal dysplasia" ]
[]
[]
[ "Secreted in other tissues" ]
[ "Receptor" ]
null
Approved
null
10
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
3,734
2
ENSG00000110422
HIPK3
Homeodomain interacting protein kinase 3
[ "Q9H422" ]
11
33256672-33357023
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028069" ]
[ "DYRK6", "FIST3", "PKY", "YAK1" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Apoptosis", "Transcription", "Transcription regulation" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Cytosol" ]
[ "Nuclear bodies" ]
[]
[]
Supported
Approved
null
1
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 39: Astrocytes - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Uterine Corpus Endometrial Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
3,735
2
ENSG00000110427
KIAA1549L
KIAA1549 like
[ "Q6ZVL6" ]
11
33376108-33674102
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA010132", "HPA051594" ]
[ "C11orf41", "C11orf69", "G2", "MGC34830" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
null
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling
Cluster 73: Brain - Neuronal signaling
Group enriched
Detected in some
14
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
3,736
1
ENSG00000110429
FBXO3
F-box protein 3
[ "Q9UK99" ]
11
33740939-33774543
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA002467" ]
[ "FBA", "FBX3" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
null
null
17
null
null
Cluster 39: T-cells - T-cell receptor
Cluster 31: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 30: Skeletal muscle - Striated muscle contraction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
3,737
3
ENSG00000110435
PDHX
Pyruvate dehydrogenase complex component X
[ "O00330" ]
11
34915829-35020591
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038484", "HPA038485" ]
[ "DLDBP", "E3BP", "OPDX", "PDX1", "proX" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Mitochondria" ]
[ "Plasma membrane" ]
[]
[]
Approved
Enhanced
null
17
null
null
Cluster 33: Non-specific - ATP binding
Cluster 34: Non-specific - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 89: Adipocytes - Lipid metabolism
Cluster 62: Skeletal muscle - Muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
3,738
1
ENSG00000110436
SLC1A2
Solute carrier family 1 member 2
[ "P43004" ]
11
35251205-35420063
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002574", "HPA009172", "HPA067499" ]
[ "EAAT2", "GLT-1", "GLT1", "HBGT" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Amino-acid transport", "Symport", "Transport" ]
[]
[ "Disease variant", "Epilepsy" ]
[]
[]
[]
[]
null
Enhanced
null
3
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in many
18
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in some
7
Cell type enriched
Detected in many
6
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
3,739
9
ENSG00000110442
COMMD9
COMM domain containing 9
[ "Q9P000" ]
11
36269284-36289449
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA009142" ]
[ "FLJ31106", "HSPC166" ]
[ "Predicted intracellular proteins" ]
[ "Ion transport", "Sodium transport", "Transcription", "Transcription regulation", "Transport", "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
Supported
Uncertain
null
42
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 27: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
3,740
8
ENSG00000110446
SLC15A3
Solute carrier family 15 member 3
[ "Q8IY34" ]
11
60937060-60952653
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047880", "HPA057642" ]
[ "hPTR3", "PHT2" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Immunity", "Innate immunity", "Peptide transport", "Protein transport", "Symport", "Transport" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Approved
null
41
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 55: Lymphoma - Immune response
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
5
0
0
0
[]
[]
[]
3,741
9
ENSG00000110448
CD5
CD5 molecule
[ "P06127" ]
11
61102489-61127852
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB015392", "CAB020308", "HPA043416", "HPA060839" ]
[ "LEU1", "T1" ]
[ "CD markers", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
Cluster 6: T-cells - T-cell receptor
Cluster 32: Cerebral cortex - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 51: Lymphoid tissue - Adaptive immune response
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
7
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Head and Neck Squamous Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Lung Adenocarcinoma" ]
3,742
2
ENSG00000110455
ACCS
1-aminocyclopropane-1-carboxylate synthase homolog (inactive)
[ "Q96QU6" ]
11
44065925-44084237
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA018873", "HPA021654" ]
[ "ACS", "PHACS" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
Approved
null
1
null
null
Cluster 29: Non-specific - Unknown function
Cluster 36: Choroid plexus - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
3,743
2
ENSG00000110484
SCGB2A2
Secretoglobin family 2A member 2
[ "Q13296" ]
11
62270158-62273160
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB026270" ]
[ "MGB1", "MGC71974", "PSBP1", "UGB2" ]
[ "Cancer-related genes", "Predicted secreted proteins" ]
[]
[]
[ "Cancer-related genes" ]
[]
[]
[ "Secreted in female reproductive system" ]
[ "No annotated function" ]
null
Enhanced
null
1
null
null
null
null
Cluster 27: Breast cancer - Unknown function
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 55: Breast - Lactation
Group enriched
Detected in some
6
Cancer enriched
Detected in some
161
Cancer enriched
Detected in many
65
Group enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
3,744
8
ENSG00000110492
MDK
Midkine
[ "P21741" ]
11
46380756-46383837
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB010055", "HPA057126" ]
[ "FLJ27379", "MK", "NEGF2" ]
[ "Cancer-related genes", "Predicted secreted proteins" ]
[ "Differentiation" ]
[ "Developmental protein", "Growth factor", "Heparin-binding", "Mitogen" ]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Growth factor" ]
Approved
Uncertain
null
15
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
2
1
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
3,745
8
ENSG00000110514
MADD
MAP kinase activating death domain
[ "Q8WXG6" ]
11
47269161-47330031
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038568" ]
[ "DENN", "KIAA0358", "RAB3GEP" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Apoptosis" ]
[ "Guanine-nucleotide releasing factor" ]
[ "Intellectual disability" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Uncertain
null
8
null
null
Cluster 32: Basophils - Transcription
Cluster 34: Non-specific - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]
3,747
9
ENSG00000110536
PTPMT1
Protein tyrosine phosphatase mitochondrial 1
[ "Q8WUK0" ]
11
47565430-47573461
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043932", "HPA060060" ]
[ "DUSP23", "MOSP", "PLIP" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid biosynthesis", "Lipid metabolism", "Phospholipid biosynthesis", "Phospholipid metabolism" ]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Enhanced
Approved
null
31
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 21: Non-specific - Metabolism
Cluster 24: Non-specific - Unknown function
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
3,748
3
ENSG00000110583
NAA40
N-alpha-acetyltransferase 40, NatD catalytic subunit
[ "Q86UY6" ]
11
63938959-63957319
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037816", "HPA056142" ]
[ "FLJ13848", "NAT11" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Acyltransferase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Centriolar satellite", "Cytosol" ]
[]
[]
Supported
Uncertain
null
31
null
null
Cluster 41: Basophils - Unknown function
Cluster 17: Choroid plexus - Cilium
Cluster 24: Non-specific - Unknown function
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 56: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
3,749
7
ENSG00000110651
CD81
CD81 molecule
[ "P60033" ]
11
2376177-2397802
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002507", "HPA007234" ]
[ "TAPA-1", "TAPA1", "TSPAN28" ]
[ "CD markers", "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Adaptive immunity", "Host-virus interaction", "Immunity" ]
[ "Host cell receptor for virus entry", "Receptor" ]
[]
[ "Plasma membrane" ]
[ "Cytosol" ]
[]
[]
Approved
Supported
null
50
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 19: Astrocytes - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Group enriched
Detected in many
4
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
3,752
8
ENSG00000110660
SLC35F2
Solute carrier family 35 member F2
[ "Q8IXU6" ]
11
107790991-107928293
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048185", "HPA060150" ]
[ "FLJ13018" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
Enhanced
null
20
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 39: Astrocytes - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 26: Keratinocytes - Keratinization
Cluster 38: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
6
0
6
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe", "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma", "Skin Cutaneous Melanoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe", "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma", "Skin Cutaneous Melanoma" ]
3,753
4
ENSG00000110665
C11orf21
Chromosome 11 open reading frame 21
[ "Q9P2W6" ]
11
2295628-2303049
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA037607" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Group enriched
Detected in many
6
Cancer enriched
Detected in some
9
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
3,754
6
ENSG00000110680
CALCA
Calcitonin related polypeptide alpha
[ "P01258", "P06881" ]
11
14966622-14972354
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059886", "HPA064453" ]
[ "CALC1", "CGRP", "CGRP-alpha" ]
[ "Cancer-related genes", "FDA approved drug targets", "Plasma proteins", "Predicted secreted proteins", "Transporters" ]
[]
[ "Hormone" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[]
[]
[ "Secreted to blood" ]
[ "Hormone" ]
null
Enhanced
Supported
7
null
null
null
Cluster 43: Hindbrain - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 103: Non-specific - Basic cellular processes
Cluster 69: Parathyroid gland - Mixed function
Group enriched
Detected in some
4
Cancer enriched
Detected in many
13
Cancer enriched
Detected in many
4
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
3,756
1
ENSG00000110693
SOX6
SRY-box transcription factor 6
[ "P35712" ]
11
15966449-16739591
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001923", "HPA003908" ]
[]
[ "Disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Transcription", "Transcription regulation" ]
[ "Activator", "Developmental protein", "DNA-binding", "Repressor" ]
[ "Autism spectrum disorder", "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Enhanced
null
20
null
null
null
Cluster 39: Astrocytes - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 14: Oligodendrocyte progenitor cells - Development & myelination
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
20
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
3,757
5
ENSG00000110696
C11orf58
Chromosome 11 open reading frame 58
[ "O00193" ]
11
16613132-16758340
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036591", "HPA076406" ]
[ "SMAP" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 41: Basophils - Unknown function
Cluster 55: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
3,758
5
ENSG00000110697
PITPNM1
Phosphatidylinositol transfer protein membrane associated 1
[ "O00562" ]
11
67491768-67506263
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA060227" ]
[ "DRES9", "NIR2", "PITPNM", "Rd9", "RDGB", "RDGB1", "RDGBA1" ]
[ "Predicted intracellular proteins", "Transporters" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Cytosol" ]
[ "Vesicles" ]
[]
[]
Supported
Approved
null
9
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 38: Sub-cortical - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 46: Brain & retina - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
3,759
1
ENSG00000110700
RPS13
Ribosomal protein S13
[ "P62277" ]
11
17074388-17077715
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA005985" ]
[ "S13" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Uncertain
null
198
null
null
Cluster 18: Non-specific - Translation
Cluster 7: Non-specific - Ribosome
Cluster 25: Non-specific - Ribosome
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
3,760
9
ENSG00000110711
AIP
Aryl hydrocarbon receptor interacting protein
[ "O00170" ]
11
67468174-67491154
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB033674", "HPA050217", "CAB069477" ]
[ "ARA9", "FKBP16", "FKBP37", "XAP2" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Cushing syndrome" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
46
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 28: Oligodendrocytes - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 97: Non-specific - Cellular respiration
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
3,761
7
ENSG00000110717
NDUFS8
NADH:ubiquinone oxidoreductase core subunit S8
[ "O00217" ]
11
68030617-68036644
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018524", "HPA067429" ]
[ "CI-23k", "TYKY" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[ "Oxidoreductase", "Translocase" ]
[ "Disease variant", "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Approved
Enhanced
null
63
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 21: Non-specific - Metabolism
Cluster 24: Non-specific - Unknown function
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Bladder Urothelial Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
3,763
6
ENSG00000110719
TCIRG1
T cell immune regulator 1, ATPase H+ transporting V0 subunit a3
[ "Q13488" ]
11
68039025-68050895
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038742" ]
[ "a3", "Atp6i", "ATP6N1C", "ATP6V0A3", "OC-116", "OC116", "TIRC7" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Hydrogen ion transport", "Ion transport", "Transport" ]
[]
[ "Disease variant", "Osteopetrosis" ]
[ "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
27
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 12: Non-specific - Vasculature
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
3,764
3
ENSG00000110721
CHKA
Choline kinase alpha
[ "P35790" ]
11
68052859-68121444
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA024153", "CAB072803" ]
[ "CHK", "CKI" ]
[ "Enzymes", "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid biosynthesis", "Lipid metabolism", "Phospholipid biosynthesis", "Phospholipid metabolism" ]
[ "Kinase", "Transferase", "Tyrosine-protein kinase" ]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Approved
null
2
null
Yes
Cluster 45: Eosinophils - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Immune cell enhanced
Detected in some
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
3,765
7
ENSG00000110756
HPS5
HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
[ "Q9UPZ3" ]
11
18278668-18322198
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA077851" ]
[ "AIBP63", "BLOC2S2", "RU2" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Albinism", "Disease variant", "Hermansky-Pudlak syndrome" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
null
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 55: Non-specific - Transcription
Cluster 69: Skin cancer - ECM organization
Cluster 102: Non-specific - Mixed function
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
3,767
8
ENSG00000110768
GTF2H1
General transcription factor IIH subunit 1
[ "P32780" ]
11
18322295-18367045
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004637", "HPA046660" ]
[ "BTF2", "P62", "TFIIH" ]
[ "Cancer-related genes", "Essential proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Host-virus interaction", "Transcription", "Transcription regulation" ]
[]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Enhanced
null
69
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 31: Non-specific - Transcription
Cluster 24: Non-specific - Unknown function
Cluster 102: Non-specific - Mixed function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
3,768
1
ENSG00000110777
POU2AF1
POU class 2 homeobox associating factor 1
[ "Q16633" ]
11
111352255-111455630
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB011193" ]
[ "BOB1", "OBF1", "OCA-B" ]
[ "Cancer-related genes", "Disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator" ]
[ "Cancer-related genes", "Proto-oncogene" ]
[]
[]
[]
[]
null
Enhanced
null
39
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 8: Immune cells - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 44: Plasma cells - Antibody production & secretion
Cluster 18: Lymphoid tissue - Immune response
Group enriched
Detected in many
4
Group enriched
Detected in many
7
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
7
2
0
2
[ "Breast Invasive Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
3,769
3
ENSG00000110786
PTPN5
Protein tyrosine phosphatase non-receptor type 5
[ "P54829" ]
11
18727928-18792721
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031014", "HPA072091" ]
[ "PTPSTEP", "STEP", "STEP61" ]
[ "Enzymes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Supported
null
23
null
null
null
Cluster 33: Neurons - Mixed function
Cluster 3: Rhabdoid - Membrane components
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in many
25
Group enriched
Detected in some
4
Group enriched
Detected in some
7
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
3,770
6
ENSG00000110799
VWF
Von Willebrand factor
[ "P04275" ]
12
5948877-6124770
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB001694", "HPA001815", "HPA002082", "CAB072874", "CAB072875" ]
[ "F8VWF" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Blood coagulation", "Cell adhesion", "Hemostasis" ]
[]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets", "von Willebrand disease" ]
[]
[]
[ "Secreted to blood" ]
[ "Blood coagulation" ]
null
Supported
null
12
null
null
null
Cluster 47: Endothelial cells - Vasculature
Cluster 48: Adipocytes & Endothelial cells - Angiogenesis
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Cancer enriched
Detected in all
4
Group enriched
Detected in many
4
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Stomach Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Stomach Adenocarcinoma" ]
3,771
8
ENSG00000110801
PSMD9
Proteasome 26S subunit, non-ATPase 9
[ "O00233" ]
12
121888732-121918297
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040512", "HPA044220" ]
[ "p27", "Rpn4" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Chaperone" ]
[]
[ "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Supported
Enhanced
null
63
null
null
Cluster 29: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 38: Non-specific - Transcription
Cluster 97: Non-specific - Cellular respiration
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
3,772
7
ENSG00000110811
P3H3
Prolyl 3-hydroxylase 3
[ "Q8IVL6" ]
12
6828407-6839847
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043695" ]
[ "GRCB", "HSU47926", "LEPREL2" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Dioxygenase", "Oxidoreductase" ]
[]
[ "Plasma membrane", "Cytosol" ]
[ "Nucleoli" ]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Approved
null
27
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
3,773
7
ENSG00000110841
PPFIBP1
PPFIA binding protein 1
[ "Q86W92" ]
12
27523431-27695564
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001924", "HPA071162" ]
[ "hSGT2", "hSgt2p", "L2", "SGT2" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes", "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Plasma membrane" ]
[]
[]
[]
Enhanced
Uncertain
null
47
null
null
Cluster 18: Non-specific - Translation
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 15: Kidney cancer - Membrane components
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 35: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
3,774
8
ENSG00000110844
PRPF40B
Pre-mRNA processing factor 40 homolog B
[ "Q6NWY9" ]
12
49568218-49644666
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038426", "HPA038599" ]
[ "HYPC" ]
[ "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[]
[]
[ "Nuclear bodies" ]
[ "Nucleoplasm", "Aggresome", "Cytosol" ]
[]
[]
Approved
Enhanced
null
6
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 32: Cerebral cortex - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
3,775
4
ENSG00000110848
CD69
CD69 molecule
[ "Q07108" ]
12
9752486-9760901
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002503", "HPA050525" ]
[ "CLEC2C" ]
[ "CD markers", "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
Enhanced
null
13
null
null
Cluster 24: Non-specific - Transcription
Cluster 8: Immune cells - Immune response
Cluster 46: Lymphoma - Humoral immune response
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 15: Bone marrow - Innate immune response
Group enriched
Detected in many
5
Group enriched
Detected in some
6
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
5
Low immune cell specificity
Detected in many
null
2
0
2
[ "Breast Invasive Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Rectum Adenocarcinoma" ]
3,776
4
ENSG00000110851
PRDM4
PR/SET domain 4
[ "Q9UKN5" ]
12
107732871-107761272
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024322", "HPA067437" ]
[ "PFM1" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Methyltransferase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
3
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 38: Non-specific - Transcription
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
3,777
8
ENSG00000110852
CLEC2B
C-type lectin domain family 2 member B
[ "Q92478" ]
12
9852369-9869386
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008194" ]
[ "AICL", "CLECSF2", "HP10085" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "No annotated function" ]
null
Enhanced
null
82
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 12: Non-specific - Vasculature
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 15: Bone marrow - Innate immune response
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
3,778
7
ENSG00000110871
COQ5
Coenzyme Q5, methyltransferase
[ "Q5HYK3" ]
12
120503279-120534434
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049487" ]
[ "MGC4767" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Ubiquinone biosynthesis" ]
[ "Methyltransferase", "Transferase" ]
[ "Primary mitochondrial disease" ]
[ "Nucleoli", "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
25
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 11: White matter - Signal transduction
Cluster 38: Non-specific - Transcription
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 19: Skeletal muscle - Striated muscle contraction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
3,779
9
ENSG00000110876
SELPLG
Selectin P ligand
[ "Q14242" ]
12
108621895-108633894
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002431", "HPA011256", "HPA069062" ]
[ "CD162", "PSGL-1" ]
[ "Candidate cardiovascular disease genes", "CD markers", "Plasma proteins", "Predicted membrane proteins" ]
[ "Cell adhesion", "Host-virus interaction" ]
[ "Host cell receptor for virus entry", "Receptor" ]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Enhanced
null
3
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 20: Macrophages & Microglia - Immune response
Cluster 51: Myeloma - Immunoglobulins
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Head and Neck Squamous Cell Carcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma" ]
3,780
2
ENSG00000110880
CORO1C
Coronin 1C
[ "Q9ULV4" ]
12
108645109-108731526
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041737" ]
[ "coronin-3", "HCRNN4" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[]
[]
[]
[]
null
Approved
null
53
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 13: Oligodendrocytes - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
3,781
2
ENSG00000110881
ASIC1
Acid sensing ion channel subunit 1
[ "P78348" ]
12
50057548-50083611
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058870" ]
[ "ACCN2", "BNaC2", "hBNaC2" ]
[ "Predicted membrane proteins" ]
[ "Calcium transport", "Ion transport", "Sodium transport", "Transport" ]
[ "Ion channel", "Sodium channel" ]
[]
[ "Golgi apparatus", "Plasma membrane" ]
[]
[]
[]
Supported
null
null
5
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 71: Lymphoma - Inflammatory response
Cluster 14: Oligodendrocyte progenitor cells - Development & myelination
Cluster 10: Brain - Synaptic signal transduction
Tissue enriched
Detected in many
6
Low cancer specificity
Detected in many
null
Cancer enriched
Detected in many
5
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma" ]
3,782
4