ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000108848 | LUC7L3 | LUC7 like 3 pre-mRNA splicing factor | [
"O95232"
] | 17 | 50719565-50756219 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018475",
"HPA018484",
"HPA020017"
] | [
"CRA",
"CREAP-1",
"CROP",
"FLJ11063",
"hLuc7A",
"LUC7A",
"OA48-18"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"DNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Enhanced | Enhanced | null | 18 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 16: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,562 | 6 |
ENSG00000108849 | PPY | Pancreatic polypeptide | [
"P01298"
] | 17 | 43940804-43942476 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016735",
"HPA032122"
] | [
"PNP"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | null | Enhanced | null | 5 | null | null | Cluster 2: Dendritic cells - Unknown function | null | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in some | 22 | Cancer enhanced | Detected in single | null | Cancer enriched | Detected in some | 114 | Cell type enriched | Detected in some | 22 | Immune cell enriched | Detected in single | 7 | 0 | 0 | 0 | [] | [] | [] | 3,563 | 7 |
ENSG00000108852 | MPP2 | MAGUK p55 scaffold protein 2 | [
"Q14168"
] | 17 | 43875357-43909711 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026486",
"HPA073483"
] | [
"DKFZp761D0712",
"DLG2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 4 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 30: White matter - Myelination | Cluster 27: Breast cancer - Unknown function | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 3,564 | 1 |
ENSG00000108854 | SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | [
"Q9HAU4"
] | 17 | 64542282-64662307 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA071508"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Enhanced | null | 84 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 7: Non-specific - Ribosome | Cluster 72: Neuronal - Signal transduction | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 43: Placenta - Pregnancy hormone signaling | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,565 | 8 |
ENSG00000108861 | DUSP3 | Dual specificity phosphatase 3 | [
"P51452"
] | 17 | 43766125-43778977 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA073671"
] | [
"VHR"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 14 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 14: Neurons - Synaptic function | Cluster 27: Breast cancer - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,566 | 3 |
ENSG00000108878 | CACNG1 | Calcium voltage-gated channel auxiliary subunit gamma 1 | [
"Q06432"
] | 17 | 67044554-67056797 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CACNLG"
] | [
"FDA approved drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel",
"Voltage-gated channel"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | 15 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 56 | Not detected | Not detected | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 26 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,567 | 3 |
ENSG00000108883 | EFTUD2 | Elongation factor Tu GTP binding domain containing 2 | [
"Q15029"
] | 17 | 44849948-44899445 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022021"
] | [
"SNRNP116",
"Snrp116",
"Snu114",
"U5-116KD"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Supported | Supported | null | 326 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 27: Breast cancer - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,568 | 9 |
ENSG00000108924 | HLF | HLF transcription factor, PAR bZIP family member | [
"Q16534"
] | 17 | 55264960-55325187 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA068156",
"HPA071210"
] | [
"MGC33822"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | 6 | Yes | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 18: Liver cancer - Metabolism | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 3,569 | 9 |
ENSG00000108932 | SLC16A6 | Solute carrier family 16 member 6 | [
"O15403"
] | 17 | 68267026-68291267 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054459",
"HPA066328"
] | [
"MCT6",
"MCT7"
] | [
"Metabolic proteins",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in all | 4 | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,570 | 2 |
ENSG00000108946 | PRKAR1A | Protein kinase cAMP-dependent type I regulatory subunit alpha | [
"P10644"
] | 17 | 68511780-68551319 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB019378",
"HPA049979"
] | [
"CNC1",
"PRKAR1",
"TSE1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes",
"Cushing syndrome",
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 67 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 17: Non-specific - RNA processing | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,571 | 5 |
ENSG00000108947 | EFNB3 | Ephrin B3 | [
"Q15768"
] | 17 | 7705202-7711372 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001623"
] | [
"EPLG8",
"LERK-8"
] | [
"Cancer-related genes",
"Predicted membrane proteins"
] | [
"Differentiation",
"Host-virus interaction",
"Neurogenesis"
] | [
"Developmental protein",
"Host cell receptor for virus entry",
"Receptor"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Approved | null | 4 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 5: Rhabdoid - Unknown function | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,572 | 4 |
ENSG00000108950 | FAM20A | FAM20A golgi associated secretory pathway pseudokinase | [
"Q96MK3"
] | 17 | 68535113-68601367 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048964"
] | [
"DKFZp434F2322"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Biomineralization"
] | [] | [
"Amelogenesis imperfecta",
"Disease variant"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Other"
] | null | Approved | null | 1 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,573 | 1 |
ENSG00000108953 | YWHAE | Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon | [
"P62258"
] | 17 | 1344275-1400222 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008445",
"CAB016200",
"CAB021109",
"CAB047350",
"HPA061603"
] | [
"FLJ45465"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Host-virus interaction"
] | [] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 1,077 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 28: Oligodendrocytes - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 102: Non-specific - Mixed function | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 3,574 | 9 |
ENSG00000108960 | MMD | Monocyte to macrophage differentiation associated | [
"Q15546"
] | 17 | 55392622-55421924 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026978"
] | [
"MMA",
"PAQR11"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Receptor"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | null | null | 19 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 47: Platelets - Hemostasis | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 11 | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 3,575 | 1 |
ENSG00000108961 | RANGRF | RAN guanine nucleotide release factor | [
"Q9HD47"
] | 17 | 8288654-8290092 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057280",
"HPA057888"
] | [
"HSPC165",
"HSPC236",
"MOG1",
"RANGNRF"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 12 | Yes | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 35: RS4;11 - Unknown function | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 3,576 | 6 |
ENSG00000108963 | DPH1 | Diphthamide biosynthesis 1 | [
"Q9BZG8"
] | 17 | 2030137-2043898 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA069750",
"HPA073864"
] | [
"DPH2L",
"DPH2L1",
"OVCA1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Transferase"
] | [
"Disease variant",
"Dwarfism",
"Ectodermal dysplasia",
"Hypotrichosis",
"Intellectual disability",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Cell Junctions"
] | [] | [] | Approved | Approved | null | 5 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 15: Non-specific - Transcription | Cluster 42: Non-specific - Unknown function | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 14 | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,577 | 1 |
ENSG00000108984 | MAP2K6 | Mitogen-activated protein kinase kinase 6 | [
"P52564"
] | 17 | 69414697-69553865 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB007744",
"HPA031134"
] | [
"MAPKK6",
"MEK6",
"MKK6",
"PRKMK6",
"SAPKK3"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Stress response",
"Transcription",
"Transcription regulation"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 22 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 25: Non-specific - Transcription | Cluster 10: Ciliated cells - Ion channel activity | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 7 | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 3,578 | 3 |
ENSG00000109016 | DHRS7B | Dehydrogenase/reductase 7B | [
"Q6IAN0"
] | 17 | 21123364-21193265 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012132",
"HPA016873"
] | [
"CGI-93",
"DKFZp566O084",
"MGC8916",
"SDR32C1"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Plasma membrane",
"Cell Junctions",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 29 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 42: Non-specific - Unknown function | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 3,579 | 9 |
ENSG00000109046 | WSB1 | WD repeat and SOCS box containing 1 | [
"Q9Y6I7"
] | 17 | 27294076-27315926 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003293"
] | [
"DKFZp564A122",
"DKFZp564B0482",
"SWIP1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 16 | null | Yes | Cluster 40: Monocytes - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 56: Non-specific - Sensory perception | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Lung Squamous Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,580 | 6 |
ENSG00000109047 | RCVRN | Recoverin | [
"P35243"
] | 17 | 9896320-9905271 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015783",
"CAB022363"
] | [
"RCV1"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Sensory transduction",
"Vision"
] | [] | [] | [
"Mid piece",
"Principal piece"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 204 | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Group enriched | Detected in some | 17 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,581 | 3 |
ENSG00000109061 | MYH1 | Myosin heavy chain 1 | [
"P12882"
] | 17 | 10492307-10518542 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001349",
"CAB010759"
] | [
"MGC133384",
"MYHa",
"MyHC-2X/D",
"MYHSA1"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Hearing"
] | [
"Actin-binding",
"Calmodulin-binding",
"Motor protein",
"Muscle protein",
"Myosin"
] | [] | [
"Focal adhesion sites"
] | [] | [] | [] | Uncertain | Enhanced | null | 11 | null | null | null | null | Cluster 64: Connective tissue cells - ECM organization | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enriched | Detected in some | 137 | Not detected | Not detected | null | Cancer enriched | Detected in single | 44 | Group enriched | Detected in some | 24 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,582 | 7 |
ENSG00000109062 | SLC9A3R1 | SLC9A3 regulator 1 | [
"O14745"
] | 17 | 74748628-74769353 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001962",
"HPA009672",
"HPA027247"
] | [
"EBP50",
"NHERF",
"NHERF1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Wnt signaling pathway"
] | [] | [
"Disease variant",
"Osteoporosis"
] | [
"Plasma membrane",
"Centriolar satellite"
] | [
"Vesicles",
"Centrosome",
"Basal body",
"Cytosol",
"Calyx"
] | [] | [] | Approved | Enhanced | null | 64 | null | Yes | Cluster 42: Non-specific - Vesicular transport | Cluster 12: Non-specific - Vasculature | Cluster 27: Breast cancer - Unknown function | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,583 | 1 |
ENSG00000109063 | MYH3 | Myosin heavy chain 3 | [
"P11055"
] | 17 | 10628526-10657309 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021808"
] | [
"HEMHC",
"MYHC-EMB",
"MYHSE1",
"SMHCE"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Calmodulin-binding",
"Motor protein",
"Muscle protein",
"Myosin"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 3 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 33: Sarcoma - Muscle contraction | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 9 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,584 | 6 |
ENSG00000109065 | NAT9 | N-acetyltransferase 9 (putative) | [
"Q9BTE0"
] | 17 | 74770529-74776367 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA021820",
"HPA057149"
] | [
"DKFZP564C103"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 25: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,585 | 9 |
ENSG00000109066 | TMEM104 | Transmembrane protein 104 | [
"Q8NE00"
] | 17 | 74776499-74839753 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044330"
] | [
"FLJ00021",
"FLJ20255"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Approved | null | null | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 30: White matter - Myelination | Cluster 27: Breast cancer - Unknown function | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,586 | 5 |
ENSG00000109072 | VTN | Vitronectin | [
"P04004"
] | 17 | 28367284-28373091 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016695",
"CAB016765",
"HPA060933",
"HPA068011"
] | [
"VN"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Plasma proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Cell adhesion"
] | [
"Heparin-binding"
] | [
"Cancer-related genes"
] | [
"Endoplasmic reticulum",
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Cell adhesion"
] | Supported | Supported | null | 21 | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 53: Liver - Plasma proteins | Tissue enriched | Detected in many | 46 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 62 | Group enriched | Detected in some | 60 | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 3,587 | 1 |
ENSG00000109079 | TNFAIP1 | TNF alpha induced protein 1 | [
"Q13829"
] | 17 | 28335602-28347009 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA013333",
"HPA014641"
] | [
"B12",
"B61",
"BTBD34",
"EDP1",
"MGC2317"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Approved | Uncertain | null | 53 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 23: Choroid plexus - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,588 | 8 |
ENSG00000109083 | IFT20 | Intraflagellar transport 20 | [
"Q8IY31"
] | 17 | 28328325-28335489 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA021376"
] | [] | [
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Differentiation",
"Spermatogenesis"
] | [] | [] | [
"Microtubules",
"Primary cilium"
] | [
"Mitotic spindle",
"Basal body",
"Flagellar centriole",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Approved | Approved | null | 73 | Yes | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 21: Non-specific - Metabolism | Cluster 27: Breast cancer - Unknown function | Cluster 33: Early spermatids - Spermiogenesis: Cap phase | Cluster 8: Pancreas - Proteolysis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,589 | 5 |
ENSG00000109084 | TMEM97 | Transmembrane protein 97 | [
"Q5BJF2"
] | 17 | 28319200-28328685 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044795",
"HPA076689"
] | [
"Ã2R",
"MAC30"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Enhanced | null | 50 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 24: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,590 | 3 |
ENSG00000109089 | CDR2L | Cerebellar degeneration related protein 2 like | [
"Q86X02"
] | 17 | 74987632-75005800 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022015"
] | [
"HUMPPA"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 80 | null | null | null | Cluster 26: Oligodendrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 71: Cerebellum - Nervous system development | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,591 | 2 |
ENSG00000109099 | PMP22 | Peripheral myelin protein 22 | [
"Q01453"
] | 17 | 15229773-15272292 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CMT1A",
"GAS3",
"HMSNIA",
"HNPP",
"Sp110"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Cancer-related genes",
"Charcot-Marie-Tooth disease",
"Deafness",
"Dejerine-Sottas syndrome",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [] | [] | [] | [] | null | null | null | 53 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 30: White matter - Myelination | Cluster 69: Skin cancer - ECM organization | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 4 | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme"
] | 3,592 | 2 |
ENSG00000109103 | UNC119 | Unc-119 lipid binding chaperone | [
"Q13432"
] | 17 | 28546708-28552631 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041912"
] | [
"HRG4",
"POC7",
"POC7A"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Endocytosis",
"Protein transport",
"Sensory transduction",
"Transport",
"Vision"
] | [] | [
"Cone-rod dystrophy",
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 56 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 1: Neurons - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 22: Non-specific - Basic cellular functions | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in all | 17 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma",
"Thyroid Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma",
"Thyroid Carcinoma"
] | 3,594 | 1 |
ENSG00000109107 | ALDOC | Aldolase, fructose-bisphosphate C | [
"P09972"
] | 17 | 28573115-28576948 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003282",
"CAB020828",
"HPA067442"
] | [] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Glycolysis"
] | [
"Lyase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Approved | Enhanced | Supported | 8 | Yes | No | Cluster 43: Non-specific - Transcription & Translation | Cluster 24: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in all | 4 | Group enriched | Detected in some | 4 | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma"
] | 3,595 | 9 |
ENSG00000109111 | SUPT6H | SPT6 homolog, histone chaperone and transcription elongation factor | [
"Q7KZ85"
] | 17 | 28662198-28702679 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB012416",
"HPA036382"
] | [
"KIAA0162",
"SPT6H"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"mRNA processing",
"mRNA splicing",
"mRNA transport",
"Transcription",
"Transport"
] | [
"Chaperone"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 46 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Breast cancer - Unknown function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,596 | 8 |
ENSG00000109113 | RAB34 | RAB34, member RAS oncogene family | [
"P0DI83",
"Q9BZG1"
] | 17 | 28714281-28718429 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA021366"
] | [
"NARR",
"RAB39",
"RAH"
] | [
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation",
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [
"Ciliopathy",
"Disease variant"
] | [
"Nucleoplasm",
"Primary cilium"
] | [
"Centrosome",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Stomach Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Stomach Adenocarcinoma"
] | 3,597 | 6 |
ENSG00000109118 | PHF12 | PHD finger protein 12 | [
"Q96QT6"
] | 17 | 28905250-28951771 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021410",
"HPA021452"
] | [
"KIAA1523",
"PF1"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 20 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 3,598 | 8 |
ENSG00000109132 | PHOX2B | Paired like homeobox 2B | [
"Q99453"
] | 4 | 41744082-41748725 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA074325",
"HPA074941"
] | [
"NBPhox",
"PMX2B"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 1 | null | null | null | Cluster 43: Hindbrain - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Group enriched | Detected in some | 12 | Cancer enriched | Detected in some | 93 | Not detected | Not detected | null | Cell type enriched | Detected in some | 72 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,599 | 3 |
ENSG00000109133 | TMEM33 | Transmembrane protein 33 | [
"P57088"
] | 4 | 41935129-41960803 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA075863"
] | [
"FLJ10525",
"Pom33"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Immunity",
"Innate immunity"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 24 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 3,600 | 2 |
ENSG00000109158 | GABRA4 | Gamma-aminobutyric acid type A receptor subunit alpha4 | [
"P48169"
] | 4 | 46918900-46993581 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"FDA approved drug targets",
"Predicted membrane proteins"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in some | 7 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,601 | 1 |
ENSG00000109171 | SLAIN2 | SLAIN motif family member 2 | [
"Q9P270"
] | 4 | 48341529-48426201 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035824",
"HPA063599"
] | [
"FLJ21611",
"KIAA1458"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Centrosome",
"Cytosol"
] | [
"Primary cilium tip",
"Basal body"
] | [] | [] | Supported | Approved | null | 24 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 16: Non-specific - Transcription | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 3,603 | 5 |
ENSG00000109180 | OCIAD1 | OCIA domain containing 1 | [
"Q9NX40"
] | 4 | 48805212-48861817 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044803",
"HPA073865"
] | [
"Asrij",
"FLJ20455",
"OCIA",
"TPA018"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 56 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 23: Choroid plexus - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,604 | 5 |
ENSG00000109181 | UGT2B10 | UDP glucuronosyltransferase family 2 member B10 | [
"P36537"
] | 4 | 68815994-68832023 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045108"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 53: Liver - Plasma proteins | Tissue enriched | Detected in some | 148 | Cancer enriched | Detected in single | 6 | Cancer enriched | Detected in single | 132 | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 3,605 | 5 |
ENSG00000109182 | CWH43 | Cell wall biogenesis 43 C-terminal homolog | [
"Q9H720"
] | 4 | 48986275-49062081 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA042814",
"HPA048140"
] | [
"CWH43-C",
"FLJ21511",
"PGAP2IP"
] | [
"Predicted membrane proteins"
] | [
"GPI-anchor biosynthesis"
] | [] | [] | [
"Golgi apparatus",
"Plasma membrane"
] | [] | [] | [] | Uncertain | Uncertain | null | 1 | null | null | null | null | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in single | 29 | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,606 | 6 |
ENSG00000109184 | DCUN1D4 | Defective in cullin neddylation 1 domain containing 4 | [
"Q92564"
] | 4 | 51843000-51916837 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036483",
"HPA036484"
] | [
"KIAA0276"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Uncertain | null | 8 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 1: Neurons - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,607 | 8 |
ENSG00000109189 | USP46 | Ubiquitin specific peptidase 46 | [
"P62068"
] | 4 | 52590960-52659301 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007288",
"CAB076369",
"CAB076370"
] | [
"FLJ12552"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Behavior",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoli",
"Nucleoli rim"
] | [] | [] | [] | Approved | Uncertain | null | 11 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 64: Connective tissue cells - ECM organization | Cluster 57: Podocytes - Glomerular filtration | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,608 | 1 |
ENSG00000109193 | SULT1E1 | Sulfotransferase family 1E member 1 | [
"P49888"
] | 4 | 69841212-69860145 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028213",
"HPA028728",
"CAB047344"
] | [
"EST",
"STE"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nuclear membrane",
"Cytosol"
] | [] | [] | [] | Uncertain | Enhanced | null | 1 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 66: Non-specific - Mitochondria | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,609 | 9 |
ENSG00000109205 | ODAM | Odontogenic, ameloblast associated | [
"A1E959"
] | 4 | 70195725-70204576 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036279",
"HPA036543",
"HPA070297"
] | [
"APin",
"FLJ20513"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Biomineralization"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [
"Intracellular and membrane"
] | [
"Other"
] | Supported | null | null | 11 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 82: Salivary gland - Secretion | Tissue enriched | Detected in some | 34 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,610 | 6 |
ENSG00000109208 | SMR3A | Submaxillary gland androgen regulated protein 3A | [
"Q99954"
] | 4 | 70360760-70367158 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044567"
] | [
"PBI",
"PRL5",
"PROL5"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to digestive system"
] | [
"No annotated function"
] | null | Enhanced | null | 3 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 82: Salivary gland - Secretion | Tissue enriched | Detected in single | 58 | Not detected | Not detected | null | Cancer enhanced | Detected in single | null | Cell type enriched | Detected in some | 25 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,611 | 1 |
ENSG00000109220 | CHIC2 | Cysteine rich hydrophobic domain 2 | [
"Q9UKJ5"
] | 4 | 54009789-54064605 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026782",
"HPA026784",
"HPA076603"
] | [
"BTL"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | [] | Enhanced | Uncertain | null | 53 | null | Yes | Cluster 35: Neutrophils - Protein binding | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 64: Connective tissue cells - ECM organization | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,612 | 7 |
ENSG00000109255 | NMU | Neuromedin U | [
"P48645"
] | 4 | 55595229-55636698 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA025926"
] | [] | [
"Predicted secreted proteins"
] | [] | [
"Neuropeptide"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Neuropeptide"
] | null | Uncertain | null | 57 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 38: Sub-cortical - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Group enriched | Detected in some | 10 | 2 | 0 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,613 | 8 |
ENSG00000109265 | CRACD | Capping protein inhibiting regulator of actin dynamics | [
"Q6ZU35"
] | 4 | 56049098-56330609 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043249",
"HPA048148"
] | [
"CRAD",
"KIAA1211"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Uncertain | null | 5 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 3,614 | 6 |
ENSG00000109270 | LAMTOR3 | Late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 | [
"Q9UHA4"
] | 4 | 99878336-99894428 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026858"
] | [
"MAP2K1IP1",
"MAPBP",
"MAPKSP1",
"MP1",
"Ragulator3"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Supported | null | 46 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 1: Neurons - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,615 | 9 |
ENSG00000109272 | PF4V1 | Platelet factor 4 variant 1 | [
"P10720"
] | 4 | 73853296-73854483 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052485"
] | [
"CXCL4L1",
"CXCL4V1",
"SCYB4V1"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Cytokine",
"Heparin-binding"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Cytokine"
] | null | Supported | null | 1 | null | null | Cluster 4: Neutrophils - Degranulation | null | Cluster 64: Connective tissue cells - ECM organization | Cluster 47: Platelets - Hemostasis | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Group enriched | Detected in some | 4 | Group enriched | Detected in some | 70 | Group enriched | Detected in some | 42 | 0 | 0 | 0 | [] | [] | [] | 3,616 | 5 |
ENSG00000109320 | NFKB1 | Nuclear factor kappa B subunit 1 | [
"P19838"
] | 4 | 102501330-102617302 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004031",
"HPA027305"
] | [
"KBF1",
"NF-kappaB",
"NF-kB1",
"NFkappaB",
"NFKB-p50",
"p105",
"p50"
] | [
"Cancer-related genes",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins",
"Transcription factors"
] | [
"Apoptosis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 124 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 59: Leukemia - T-cell receptor | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,617 | 1 |
ENSG00000109321 | AREG | Amphiregulin | [
"P15514"
] | 4 | 74445136-74455005 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008720",
"CAB023519"
] | [
"AR",
"AREGB",
"SDGF"
] | [
"Cancer-related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [
"Cytokine",
"Growth factor"
] | [
"Cancer-related genes"
] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 4 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 12: Non-specific - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 11 | 5 | 2 | 4 | [
"Rectum Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,618 | 8 |
ENSG00000109323 | MANBA | Mannosidase beta | [
"O00462"
] | 4 | 102630770-102760994 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037698",
"HPA047826",
"HPA053478"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Glycosidase",
"Hydrolase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Enhanced | Approved | null | 19 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 49: Hindbrain - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 3,619 | 2 |
ENSG00000109339 | MAPK10 | Mitogen-activated protein kinase 10 | [
"P53779"
] | 4 | 85990007-86594625 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022625",
"HPA068627",
"HPA071800"
] | [
"JNK3",
"p493F12",
"p54bSAPK",
"PRKM10"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Biological rhythms"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 26 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 14: Neurons - Synaptic function | Cluster 46: Lymphoma - Humoral immune response | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 3,621 | 6 |
ENSG00000109381 | ELF2 | E74 like ETS transcription factor 2 | [
"Q15723"
] | 4 | 139028112-139177218 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006057",
"HPA071166"
] | [
"EU32",
"NERF",
"NERF-1A",
"NERF-1B",
"NERF-2"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Enhanced | null | 10 | null | null | Cluster 24: Non-specific - Transcription | Cluster 26: Oligodendrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 5 | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,622 | 4 |
ENSG00000109390 | NDUFC1 | NADH:ubiquinone oxidoreductase subunit C1 | [
"O43677"
] | 4 | 139266880-139302551 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044556",
"HPA062427"
] | [
"KFYI"
] | [
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Electron transport",
"Respiratory chain",
"Transport"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | null | No | No | Cluster 46: Basophils - Proteolysis | Cluster 55: Non-specific - Transcription | Cluster 66: Non-specific - Mitochondria | Cluster 97: Non-specific - Cellular respiration | Cluster 62: Skeletal muscle - Muscle contraction | Group enriched | Detected in all | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,623 | 3 |
ENSG00000109424 | UCP1 | Uncoupling protein 1 | [
"P25874"
] | 4 | 140559431-140568961 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012022",
"CAB037199",
"HPA068364"
] | [
"SLC25A7",
"UCP"
] | [
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel"
] | [
"Diabetes mellitus",
"Obesity"
] | [] | [] | [] | [] | null | Supported | null | null | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 34: Testis cancer - Unknown function | Cluster 65: Non-specific - Cell growth & division | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in single | null | Cancer enriched | Detected in single | 5 | Cancer enriched | Detected in single | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,624 | 2 |
ENSG00000109436 | TBC1D9 | TBC1 domain family member 9 | [
"Q6ZT07"
] | 4 | 140620782-140756385 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA000262",
"HPA006503"
] | [
"GRAMD9",
"KIAA0882",
"MDR1"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 11 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 23: Choroid plexus - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 82: Dendritic cells - Antigen presentation | Cluster 13: Lung - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,625 | 6 |
ENSG00000109452 | INPP4B | Inositol polyphosphate-4-phosphatase type II B | [
"O15327"
] | 4 | 142023160-142847432 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037681",
"HPA037682"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Centrosome"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 11: T-cells - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 110: Mural cells - ECM organization | Cluster 57: Testis - Spermatogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,627 | 6 |
ENSG00000109466 | KLHL2 | Kelch like family member 2 | [
"O95198"
] | 4 | 165207561-165323156 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051637"
] | [
"MAV"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Ubl conjugation pathway"
] | [
"Actin-binding"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Uncertain | null | null | 40 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Immune cell enhanced | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 3,629 | 8 |
ENSG00000109472 | CPE | Carboxypeptidase E | [
"P16870"
] | 4 | 165361194-165498547 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003819",
"CAB024907",
"CAB080183"
] | [] | [
"Disease related genes",
"Enzymes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Carboxypeptidase",
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Disease variant",
"Hypogonadotropic hypogonadism",
"Intellectual disability",
"Obesity"
] | [
"Vesicles",
"Centrosome"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Approved | Supported | null | 2 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 3,631 | 2 |
ENSG00000109475 | RPL34 | Ribosomal protein L34 | [
"P49207"
] | 4 | 108620569-108630412 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035139",
"HPA076722"
] | [
"L34"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [
"Nucleoli"
] | [] | [] | Supported | Uncertain | null | 81 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 3,632 | 1 |
ENSG00000109501 | WFS1 | Wolframin ER transmembrane glycoprotein | [
"O76024"
] | 4 | 6269849-6303265 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029128"
] | [
"DFNA14",
"DFNA38",
"DFNA6",
"DIDMOAD",
"WFS"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Cataract",
"Deafness",
"Diabetes insipidus",
"Diabetes mellitus",
"Disease variant",
"Non-syndromic deafness"
] | [] | [] | [] | [] | null | Approved | null | 340 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Lung Squamous Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | 3,633 | 8 |
ENSG00000109511 | ANXA10 | Annexin A10 | [
"Q9UJ72"
] | 4 | 168092537-168187736 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005469",
"HPA074650"
] | [
"ANX14"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [
"Vesicles"
] | [] | [] | Approved | Enhanced | null | 5 | null | null | null | null | Cluster 66: Non-specific - Mitochondria | Cluster 68: Foveolar cells - Mucosal defense | Cluster 60: Stomach - Digestion | Tissue enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,634 | 8 |
ENSG00000109519 | GRPEL1 | GrpE like 1, mitochondrial | [
"Q9HAV7"
] | 4 | 7058671-7068085 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036647"
] | [
"FLJ25609",
"GrpE",
"hMGE"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Supported | null | 22 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 27: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 3,635 | 2 |
ENSG00000109534 | GAR1 | GAR1 ribonucleoprotein | [
"Q9NY12"
] | 4 | 109815510-109824740 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059098"
] | [
"NOLA1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis",
"rRNA processing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [] | [] | [] | Approved | Supported | null | 30 | null | Yes | Cluster 24: Non-specific - Transcription | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 4 | 2 | [
"Rectum Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 3,636 | 8 |
ENSG00000109536 | FRG1 | FSHD region gene 1 | [
"Q14331"
] | 4 | 189940870-189963202 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA075683"
] | [
"FRG1A",
"FSG1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"Myogenesis",
"Ribosome biogenesis",
"rRNA processing"
] | [
"Actin-binding",
"RNA-binding"
] | [] | [] | [] | [] | [] | null | Approved | null | 9 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,637 | 7 |
ENSG00000109572 | CLCN3 | Chloride voltage-gated channel 3 | [
"P51790"
] | 4 | 169612633-169723673 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044723"
] | [
"ClC-3",
"CLC3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Antiport",
"Ion transport",
"Transport"
] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | 5 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,638 | 4 |
ENSG00000109576 | AADAT | Aminoadipate aminotransferase | [
"Q8N5Z0"
] | 4 | 170060222-170091699 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037502"
] | [
"KAT2",
"KATII",
"KYAT2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Aminotransferase",
"Transferase"
] | [] | [
"Plasma membrane"
] | [
"Vesicles"
] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 3,639 | 4 |
ENSG00000109586 | GALNT7 | Polypeptide N-acetylgalactosaminyltransferase 7 | [
"Q86SF2"
] | 4 | 173168811-173323967 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064243",
"HPA065317"
] | [
"GALNAC-T7"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 5 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 25: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 3,640 | 6 |
ENSG00000109606 | DHX15 | DEAH-box helicase 15 | [
"O43143"
] | 4 | 24517441-24584554 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047047"
] | [
"DBP1",
"DDX15",
"HRH2",
"PRP43",
"PRPF43",
"PrPp43p"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity",
"mRNA processing",
"mRNA splicing"
] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Enhanced | Approved | null | 103 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 17: Non-specific - RNA processing | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,641 | 1 |
ENSG00000109610 | SOD3 | Superoxide dismutase 3 | [
"P08294"
] | 4 | 24789912-24800842 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042110"
] | [
"EC-SOD"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Antioxidant",
"Heparin-binding",
"Oxidoreductase"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Supported | null | 6 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 1: Choroid plexus - Transmembrane transport | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 3,642 | 6 |
ENSG00000109625 | CPZ | Carboxypeptidase Z | [
"Q66K79"
] | 4 | 8592660-8619759 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078608"
] | [] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Wnt signaling pathway"
] | [
"Carboxypeptidase",
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Plasma membrane"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Approved | null | null | null | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Thyroid Carcinoma"
] | 3,644 | 3 |
ENSG00000109654 | TRIM2 | Tripartite motif containing 2 | [
"Q9C040"
] | 4 | 153152163-153339319 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035853",
"HPA035854"
] | [
"CMT2R",
"KIAA0517",
"RNF86"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Charcot-Marie-Tooth disease",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Centrosome"
] | [] | [] | [] | Uncertain | Supported | null | 19 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in single | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,645 | 7 |
ENSG00000109667 | SLC2A9 | Solute carrier family 2 member 9 | [
"Q9NRM0"
] | 4 | 9771153-10054936 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066229",
"HPA075669"
] | [
"Glut9",
"GLUTX",
"URATv1"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 3 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enriched | Detected in many | 9 | Immune cell enhanced | Detected in some | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Thyroid Carcinoma"
] | 3,646 | 6 |
ENSG00000109674 | NEIL3 | Nei like DNA glycosylase 3 | [
"Q8TAT5"
] | 4 | 177309874-177362936 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065761"
] | [
"FLJ10858",
"FPG2",
"hFPG2",
"hNEI3",
"ZGRF3"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"DNA-binding",
"Glycosidase",
"Hydrolase",
"Lyase",
"Multifunctional enzyme"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | 12 | null | Yes | Cluster 9: T-regs - Cell cycle regulation | null | Cluster 59: Leukemia - T-cell receptor | Cluster 27: Non-specific - Cell proliferation | Cluster 80: Thymus - Adaptive immune response | Group enriched | Detected in some | 6 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 3,648 | 3 |
ENSG00000109680 | TBC1D19 | TBC1 domain family member 19 | [
"Q8N5T2"
] | 4 | 26576437-26756223 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039592"
] | [
"FLJ11082"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Nuclear membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 45: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,649 | 6 |
ENSG00000109684 | CLNK | Cytokine dependent hematopoietic cell linker | [
"Q7Z7G1"
] | 4 | 10486395-10684768 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035671",
"HPA035672"
] | [
"MIST"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Uncertain | null | 9 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 48: Non-specific - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in some | 23 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,650 | 1 |
ENSG00000109685 | NSD2 | Nuclear receptor binding SET domain protein 2 | [
"O96028"
] | 4 | 1871393-1982207 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015801",
"CAB068246",
"CAB068247"
] | [
"KMT3G",
"MMSET",
"WHSC1"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"DNA-binding",
"Methyltransferase",
"Transferase"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability",
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Supported | Enhanced | null | 77 | No | No | Cluster 20: Non-specific - DNA binding | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 51: Myeloma - Immunoglobulins | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,651 | 8 |
ENSG00000109686 | SH3D19 | SH3 domain containing 19 | [
"Q5HYK7"
] | 4 | 151102751-151325605 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016424",
"HPA058562"
] | [
"DKFZp434D0215",
"EBP",
"Eve-1",
"EVE1",
"Kryn",
"SH3P19"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 17 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 3,652 | 8 |
ENSG00000109689 | STIM2 | Stromal interaction molecule 2 | [
"Q9P246"
] | 4 | 26857601-27025381 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036933",
"CAB037196",
"HPA057511"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Supported | null | 16 | null | null | Cluster 24: Non-specific - Transcription | Cluster 23: Choroid plexus - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 3,653 | 4 |
ENSG00000109736 | MFSD10 | Major facilitator superfamily domain containing 10 | [
"Q14728"
] | 4 | 2930561-2934834 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043209"
] | [
"IT10C3",
"TETRAN"
] | [
"Predicted membrane proteins"
] | [
"Apoptosis",
"Transport"
] | [] | [] | [
"Nuclear membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 8 | No | No | Cluster 45: Eosinophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 15: Non-specific - Protein processing | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 3,655 | 9 |
ENSG00000109738 | GLRB | Glycine receptor beta | [
"P48167"
] | 4 | 157076125-157172090 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA052363"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport"
] | [
"Chloride channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 72: Neuronal - Signal transduction | Cluster 109: Neurons - Neuronal signaling | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 3,656 | 5 |
ENSG00000109743 | BST1 | Bone marrow stromal cell antigen 1 | [
"Q10588"
] | 4 | 15703065-15738313 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050121"
] | [
"BST-1",
"cADPR2",
"CD157"
] | [
"CD markers",
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Transferase"
] | [
"FDA approved drug targets"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Uncertain | null | null | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 48: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 15: Bone marrow - Innate immune response | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 3,657 | 5 |
ENSG00000109756 | RAPGEF2 | Rap guanine nucleotide exchange factor 2 | [
"Q9Y4G8"
] | 4 | 159103013-159360174 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA068798"
] | [
"DKFZP586O1422",
"KIAA0313",
"PDZ-GEF1",
"PDZGEF1",
"RA-GEF"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein",
"GTPase activation",
"Guanine-nucleotide releasing factor"
] | [
"Epilepsy"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | null | null | 20 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 53: Neurons - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 3,658 | 5 |
ENSG00000109758 | HGFAC | HGF activator | [
"Q04756"
] | 4 | 3441968-3449486 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058279",
"HPA059076"
] | [
"HGFA",
"HGFAP"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Enhanced | null | 5 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 57 | Cancer enhanced | Detected in single | null | Cancer enriched | Detected in some | 8 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 3,659 | 1 |
ENSG00000109762 | SNX25 | Sorting nexin 25 | [
"Q9H3E2"
] | 4 | 185204237-185370185 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036928"
] | [
"SBBI31"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Protein transport",
"Transport"
] | [] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [] | [] | [] | Supported | null | null | 3 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 64: Connective tissue cells - ECM organization | Cluster 81: Alveolar cells - Lung function | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,660 | 4 |
ENSG00000109771 | LRP2BP | LRP2 binding protein | [
"Q9P2M1"
] | 4 | 185363872-185395924 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036664",
"HPA036665"
] | [
"DKFZp761O0113"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Uncertain | Approved | null | 18 | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 55: Lymphoma - Immune response | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,661 | 5 |
ENSG00000109775 | UFSP2 | UFM1 specific peptidase 2 | [
"Q9NUQ7"
] | 4 | 185399537-185425979 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039985",
"HPA043298"
] | [
"C4orf20",
"FLJ11200"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Disease variant",
"Dwarfism",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 38 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 50: Non-specific - Nucleic acid binding | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 3,662 | 7 |
ENSG00000109787 | KLF3 | KLF transcription factor 3 | [
"P57682"
] | 4 | 38664197-38701517 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049512",
"HPA065054"
] | [
"BKLF"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 81 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 47: Leukemia - Hemostasis | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 3,663 | 9 |
ENSG00000109790 | KLHL5 | Kelch like family member 5 | [
"Q96PQ7"
] | 4 | 39045039-39126857 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013958",
"HPA079699"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Plasma membrane",
"Microtubules"
] | [] | [] | [] | Approved | Approved | null | 4 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 3,664 | 1 |
ENSG00000109794 | FAM149A | Family with sequence similarity 149 member A | [
"A5PLN7"
] | 4 | 186104419-186175337 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA044019",
"HPA055004"
] | [
"DKFZP564J102",
"MST119",
"MSTP119"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 29: Forebrain - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 4 | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,665 | 4 |
ENSG00000109805 | NCAPG | Non-SMC condensin I complex subunit G | [
"Q9BPX3"
] | 4 | 17810979-17844865 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039613"
] | [
"CAP-G",
"FLJ12450",
"hCAP-G",
"YCG1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA condensation",
"Mitosis"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 28 | null | Yes | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 4 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 3,666 | 1 |
ENSG00000109814 | UGDH | UDP-glucose 6-dehydrogenase | [
"O60701"
] | 4 | 39498755-39528311 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB034444",
"HPA036656",
"HPA036657"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism"
] | [
"Allosteric enzyme",
"Oxidoreductase"
] | [
"Disease variant",
"Epilepsy"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 4 | Yes | No | Cluster 41: Basophils - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 7: Liver cancer - Metabolism | Cluster 65: Non-specific - Cell growth & division | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 3,667 | 8 |
ENSG00000109819 | PPARGC1A | PPARG coactivator 1 alpha | [
"Q9UBK2"
] | 4 | 23755041-23904089 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA063176"
] | [
"PGC-1alpha",
"PGC1",
"PGC1A",
"PPARAGCIalpha",
"PPARGC1"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"RNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 36 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 6 | 0 | 6 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Thyroid Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Thyroid Carcinoma"
] | 3,668 | 3 |
ENSG00000109832 | DDX25 | DEAD-box helicase 25 | [
"Q9UHL0"
] | 11 | 125903348-125943702 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020137"
] | [
"GRTH"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"mRNA transport",
"Spermatogenesis",
"Translation regulation",
"Transport"
] | [
"Developmental protein",
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 2 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 24: Non-specific - Unknown function | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Skin Cutaneous Melanoma"
] | [
"Skin Cutaneous Melanoma"
] | 3,669 | 5 |
ENSG00000109846 | CRYAB | Crystallin alpha B | [
"P02511"
] | 11 | 111908564-111923722 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002053",
"CAB040560",
"HPA057100"
] | [
"CRYA2",
"HSPB5"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Chaperone",
"Eye lens protein"
] | [
"Cancer-related genes",
"Cardiomyopathy",
"Cataract",
"Disease variant",
"Myofibrillar myopathy"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [
"Intracellular and membrane"
] | [
"Other"
] | Enhanced | Enhanced | null | 74 | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in all | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 3,670 | 4 |
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