ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000118785
SPP1
Secreted phosphoprotein 1
[ "P10451" ]
4
87975667-87983532
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA027540", "HPA027541" ]
[ "BNSP", "BSPI", "ETA-1", "OPN" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted secreted proteins" ]
[ "Biomineralization", "Cell adhesion" ]
[ "Cytokine" ]
[ "Cancer-related genes" ]
[ "Golgi apparatus" ]
[]
[ "Secreted to blood" ]
[ "Cytokine" ]
Enhanced
Enhanced
null
12
null
null
Cluster 4: Neutrophils - Degranulation
Cluster 30: White matter - Myelination
Cluster 15: Kidney cancer - Membrane components
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 72: Kidney - Transmembrane transport
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
5
Immune cell enriched
Detected in some
11
4
0
4
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
4,798
5
ENSG00000118804
STBD1
Starch binding domain 1
[ "O95210" ]
4
76306733-76311130
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011952", "HPA012849" ]
[ "FLJ41801", "GENX-3414" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Autophagy", "Carbohydrate metabolism", "Glycogen metabolism" ]
[]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Enhanced
null
26
null
null
Cluster 25: Non-specific - Unknown function
Cluster 49: Hindbrain - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 63: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
4,799
2
ENSG00000118816
CCNI
Cyclin I
[ "Q14094" ]
4
77047155-77076309
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB010206", "HPA039853", "HPA061470" ]
[ "CCNI1" ]
[ "Predicted intracellular proteins" ]
[]
[ "Cyclin" ]
[]
[ "Golgi apparatus" ]
[ "Nucleoplasm", "Nuclear bodies" ]
[]
[]
Approved
Uncertain
null
7
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 15: Non-specific - Protein processing
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,800
8
ENSG00000118849
RARRES1
Retinoic acid receptor responder 1
[ "P49788" ]
3
158696892-158732489
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003892" ]
[ "LXNL", "TIG1" ]
[ "Predicted intracellular proteins" ]
[]
[ "Protease inhibitor" ]
[]
[ "Golgi apparatus" ]
[ "Endoplasmic reticulum" ]
[ "Intracellular and membrane" ]
[ "Enzyme inhibitor" ]
Approved
Uncertain
null
1
null
null
null
Cluster 23: Choroid plexus - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Group enriched
Detected in many
7
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
4,801
5
ENSG00000118855
MFSD1
Major facilitator superfamily domain containing 1
[ "Q9H3U5" ]
3
158732198-158829719
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA065858" ]
[ "FLJ14153", "Minerva", "UG0581B09" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Transport" ]
[]
[]
[ "Plasma membrane" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,802
1
ENSG00000118873
RAB3GAP2
RAB3 GTPase activating non-catalytic protein subunit 2
[ "Q9H2M9" ]
1
220148293-220272529
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026273", "HPA027299" ]
[ "DKFZP434D245", "KIAA0839", "RAB3-GAP150", "SPG69" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "GTPase activation" ]
[ "Cataract", "Disease variant", "Intellectual disability" ]
[ "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Supported
Approved
null
15
null
null
Cluster 32: Basophils - Transcription
Cluster 44: Non-specific - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 7: Non-specific - Transcription
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
4,803
1
ENSG00000118894
EEF2KMT
Eukaryotic elongation factor 2 lysine methyltransferase
[ "Q96G04" ]
16
5084284-5097795
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041610" ]
[ "EFM3", "FAM86A", "MGC19636", "SB153" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "Methyltransferase", "Transferase" ]
[]
[ "Vesicles" ]
[]
[]
[]
Uncertain
Approved
null
14
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 38: Sub-cortical - Mixed function
Cluster 54: Non-specific - Transcription
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
13
Low immune cell specificity
Detected in many
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
4,804
7
ENSG00000118898
PPL
Periplakin
[ "O60437" ]
16
4882507-4960741
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042550", "HPA059859" ]
[]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Keratinization" ]
[]
[]
[ "Plasma membrane", "Basal body", "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Uncertain
Enhanced
null
65
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
6
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Glioblastoma Multiforme", "Ovary Serous Cystadenocarcinoma" ]
[ "Glioblastoma Multiforme", "Ovary Serous Cystadenocarcinoma" ]
4,805
7
ENSG00000118900
UBN1
Ubinuclein 1
[ "Q9NPG3" ]
16
4846665-4882401
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA061029", "HPA069036", "HPA069045" ]
[]
[ "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[ "Chromatin regulator", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Supported
Supported
null
14
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 15: Non-specific - Transcription
Cluster 54: Non-specific - Transcription
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enriched
Detected in many
8
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,806
8
ENSG00000118922
KLF12
KLF transcription factor 12
[ "Q9Y4X4" ]
13
73686089-74134404
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA064146", "HPA075652" ]
[ "AP-2rep", "AP2REP", "HSPC122" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Repressor" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
40
null
null
Cluster 1: T-cells - Unknown function
Cluster 1: Neurons - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 32: Retina & Lymphoid tissues - Signaling
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,807
8
ENSG00000118939
UCHL3
Ubiquitin C-terminal hydrolase L3
[ "P15374" ]
13
75549480-75606020
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019678", "CAB037139", "CAB037208" ]
[]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Approved
null
22
No
No
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 33: Neurons - Mixed function
Cluster 19: Non-specific - Unknown function
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
4,808
6
ENSG00000118946
PCDH17
Protocadherin 17
[ "O14917" ]
13
57631744-57729311
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA026817" ]
[ "PCDH68", "PCH68" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Vesicles", "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Approved
Uncertain
null
2
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 12: Bone cancer - Neuronal signaling
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,809
2
ENSG00000118960
HS1BP3
HCLS1 binding protein 3
[ "Q53T59" ]
2
20560448-20651130
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035050" ]
[ "HS1-BP3,FLJ14249" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
12
No
No
Cluster 7: Non-specific - Innate immune response
Cluster 11: White matter - Signal transduction
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,810
9
ENSG00000118961
LDAH
Lipid droplet associated hydrolase
[ "Q9H6V9" ]
2
20684014-20823130
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA034729", "HPA034730" ]
[ "C2orf43", "FLJ21820" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
Cluster 14: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
4,811
9
ENSG00000118965
WDR35
WD repeat domain 35
[ "Q9P2L0" ]
2
19910263-19990105
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044147" ]
[ "FAP118", "IFT121", "IFTA1", "KIAA1336", "MGC33196" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "Cilium biogenesis/degradation" ]
[]
[ "Ciliopathy", "Disease variant", "Ectodermal dysplasia" ]
[]
[]
[]
[]
null
Approved
null
12
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
5
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,812
4
ENSG00000118971
CCND2
Cyclin D2
[ "P30279" ]
12
4269771-4305353
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049138", "HPA054196" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division" ]
[ "Cyclin" ]
[ "Cancer-related genes", "Disease variant" ]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Approved
null
36
Yes
Yes
Cluster 3: Non-specific - Nuclear processes
Cluster 51: Neurons - Mixed function
Cluster 21: Lymphoma - Adaptive immune response
Cluster 44: Plasma cells - Antibody production & secretion
Cluster 35: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Breast Invasive Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Pancreatic Adenocarcinoma" ]
4,813
5
ENSG00000118972
FGF23
Fibroblast growth factor 23
[ "Q9GZV9" ]
12
4368227-4379712
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA048995" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted secreted proteins", "RAS pathway related proteins", "Transporters" ]
[ "Differentiation" ]
[ "Growth factor" ]
[ "Cancer-related genes", "Disease variant" ]
[ "Vesicles" ]
[ "Nuclear bodies", "Centrosome", "Cytosol" ]
[ "Secreted to blood" ]
[ "Growth factor" ]
Approved
null
null
5
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 23: Choroid plexus - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Group enriched
Detected in many
4
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in all
null
0
0
0
[]
[]
[]
4,814
2
ENSG00000118985
ELL2
Elongation factor for RNA polymerase II 2
[ "O00472" ]
5
95885098-95961851
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA013569" ]
[ "MRCCAT1" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
null
null
28
No
No
Cluster 22: Eosinophils - Transcription
Cluster 11: White matter - Signal transduction
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
0
3
[]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma", "Thyroid Carcinoma" ]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma", "Thyroid Carcinoma" ]
4,815
5
ENSG00000118997
DNAH7
Dynein axonemal heavy chain 7
[ "Q8WXX0" ]
2
195737703-196068837
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034724", "HPA044070" ]
[ "KIAA0944" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Motor protein" ]
[ "Ciliopathy", "Primary ciliary dyskinesia" ]
[ "Mid piece", "Annulus" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Supported
Enhanced
null
null
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 50: Lymphoma - Unknown function
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,816
5
ENSG00000119004
CYP20A1
Cytochrome P450 family 20 subfamily A member 1
[ "Q6UW02" ]
2
203238977-203306026
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA055872", "HPA058461" ]
[ "CYP-M" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Monooxygenase", "Oxidoreductase" ]
[]
[ "Plasma membrane", "Cell Junctions", "Actin filaments" ]
[ "Nucleoplasm" ]
[]
[]
Uncertain
Uncertain
null
3
No
No
Cluster 16: Non-specific - Cell proliferation
Cluster 6: Non-specific - Immune response
Cluster 63: Non-specific - Protein processing
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,817
1
ENSG00000119013
NDUFB3
NADH:ubiquinone oxidoreductase subunit B3
[ "O43676" ]
2
201071433-201085750
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034596" ]
[ "B12" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Predicted membrane proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[]
[ "Disease variant", "Primary mitochondrial disease" ]
[]
[]
[]
[]
null
Enhanced
null
83
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 21: Non-specific - Metabolism
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
6
2
5
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,818
5
ENSG00000119041
GTF3C3
General transcription factor IIIC subunit 3
[ "Q9Y5Q9" ]
2
196763035-196799725
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA069179" ]
[ "TFIIIC102", "TFiiiC2-102" ]
[ "Essential proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Transcription" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Nuclear membrane" ]
[ "Nucleoli fibrillar center" ]
[]
[]
Supported
null
null
77
null
null
Cluster 30: Non-specific - DNA binding
Cluster 50: Non-specific - Nucleic acid binding
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 7: Non-specific - Transcription
Cluster 40: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,819
7
ENSG00000119042
SATB2
SATB homeobox 2
[ "Q9UPW6" ]
2
199269505-199471266
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001042", "CAB023669", "HPA029543", "CAB062562", "CAB067751", "CAB068229", "CAB068230", "CAB068231" ]
[ "FLJ21474", "KIAA1034" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Developmental protein", "DNA-binding", "Repressor" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Centrosome", "Basal body", "Cytosol" ]
[]
[]
Supported
Enhanced
null
24
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 17: Intestine - Digestion
Group enriched
Detected in many
5
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
4,820
5
ENSG00000119048
UBE2B
Ubiquitin conjugating enzyme E2 B
[ "P63146" ]
5
134371184-134392108
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003875", "HPA051765", "HPA065898" ]
[ "HHR6B", "RAD6B", "UBC2" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Nucleoplasm", "Plasma membrane", "Cytosol" ]
[ "Vesicles", "Flagellar centriole", "Mid piece", "Principal piece" ]
[]
[]
Approved
null
null
27
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 31: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
4,821
8
ENSG00000119121
TRPM6
Transient receptor potential cation channel subfamily M member 6
[ "Q9BX84" ]
9
74722495-74888094
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CHAK2", "FLJ22628", "HOMG", "HSH" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[ "Calcium channel", "Ion channel", "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Disease variant", "Primary hypomagnesemia" ]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 46: Basophils - Proteolysis
Cluster 26: Oligodendrocytes - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 77: Intestine - Digestion
Tissue enriched
Detected in some
5
Cancer enhanced
Detected in single
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
6
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
4,822
3
ENSG00000119125
GDA
Guanine deaminase
[ "Q9Y2T3" ]
9
72114595-72257193
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019352", "HPA024099", "HPA030387" ]
[ "CYPIN", "GAH" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Enhanced
null
3
No
null
null
Cluster 51: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 10: Brain - Synaptic signal transduction
Group enriched
Detected in many
4
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,823
8
ENSG00000119139
TJP2
Tight junction protein 2
[ "Q9UDY2" ]
9
69121264-69274615
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001813", "CAB009228", "HPA070714" ]
[ "DFNA51", "X104", "ZO-2", "ZO2" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes", "Disease variant", "Intrahepatic cholestasis" ]
[ "Plasma membrane", "Cell Junctions" ]
[ "Nucleoplasm" ]
[]
[]
Enhanced
Supported
null
53
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 13: Oligodendrocytes - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 42: Retina - Visual perception
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,825
8
ENSG00000119147
ECRG4
ECRG4 augurin precursor
[ "Q9H1Z8" ]
2
106063246-106078155
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA008546" ]
[ "augurin", "C2orf40" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to blood" ]
[ "No annotated function" ]
null
Uncertain
null
2
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 36: Choroid plexus - Mixed function
Cluster 11: Neuronal - Sensory perception
Cluster 110: Mural cells - ECM organization
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in many
null
Not detected
Not detected
null
Cancer enriched
Detected in many
12
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
4,826
9
ENSG00000119185
ITGB1BP1
Integrin subunit beta 1 binding protein 1
[ "O14713" ]
2
9403475-9423528
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA067348", "HPA071538" ]
[ "ICAP-1A", "ICAP-1alpha", "ICAP-1B", "ICAP1", "ICAP1A", "ICAP1B" ]
[ "Predicted intracellular proteins", "Transporters" ]
[ "Angiogenesis", "Biomineralization", "Cell adhesion", "Differentiation", "Notch signaling pathway", "Transcription", "Transcription regulation" ]
[ "Mitogen" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies", "Cytosol" ]
[]
[]
Supported
null
null
14
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 108: Fibroblasts - ECM organization
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
4
2
3
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
4,827
8
ENSG00000119203
CPSF3
Cleavage and polyadenylation specific factor 3
[ "Q9UKF6" ]
2
9423651-9473101
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA034657" ]
[ "CPSF-73", "CPSF73", "YSH1" ]
[ "Disease related genes", "Essential proteins", "Predicted intracellular proteins" ]
[ "mRNA processing" ]
[ "Endonuclease", "Hydrolase", "Nuclease", "Ribonucleoprotein", "RNA-binding" ]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[]
[]
[]
[]
null
Uncertain
null
24
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 28: Oligodendrocytes - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Lung Squamous Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
4,828
9
ENSG00000119227
PIGZ
Phosphatidylinositol glycan anchor biosynthesis class Z
[ "Q86VD9" ]
3
196946356-196969060
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA058599", "HPA059920" ]
[ "FLJ12768", "MGC52163", "SMP3" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "GPI-anchor biosynthesis" ]
[ "Glycosyltransferase", "Transferase" ]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 1: Neurons - Mixed function
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Colon Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
4,829
2
ENSG00000119231
SENP5
SUMO specific peptidase 5
[ "Q96HI0" ]
3
196867856-196934714
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "MGC27076" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[]
[]
[]
[]
null
null
null
23
null
null
Cluster 32: Basophils - Transcription
Cluster 34: Non-specific - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme" ]
[ "Kidney Chromophobe", "Prostate Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Prostate Adenocarcinoma" ]
4,830
9
ENSG00000119280
C1orf198
Chromosome 1 open reading frame 198
[ "Q9H425" ]
1
230837119-230869589
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004798" ]
[ "DKFZp667D152", "FLJ14525", "FLJ16283", "FLJ38847", "MGC10710" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
4
null
null
Cluster 14: Non-specific - Unknown function
Cluster 13: Oligodendrocytes - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
4
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
4,832
9
ENSG00000119283
TRIM67
Tripartite motif containing 67
[ "Q6ZTA4" ]
1
231162058-231221565
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA034776" ]
[ "TNL" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
10
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 109: Neurons - Neuronal signaling
Cluster 27: Cerebellum - Synaptic function
Group enriched
Detected in some
11
Cancer enriched
Detected in some
7
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
4,833
8
ENSG00000119285
HEATR1
HEAT repeat containing 1
[ "Q9H583" ]
1
236549005-236604516
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046917", "HPA062200" ]
[ "BAP28", "FLJ10359", "UTP10" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Ribosome biogenesis", "rRNA processing", "Transcription", "Transcription regulation" ]
[ "Ribonucleoprotein" ]
[]
[ "Nucleoli fibrillar center" ]
[ "Mitochondria" ]
[]
[]
Enhanced
Approved
null
40
null
null
Cluster 24: Non-specific - Transcription
Cluster 28: Oligodendrocytes - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 17: Non-specific - RNA processing
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
0
4
[ "Rectum Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
4,834
3
ENSG00000119314
PTBP3
Polypyrimidine tract binding protein 3
[ "O95758" ]
9
112217716-112333664
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA048374" ]
[ "DKFZp781I1117", "ROD1" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Erythrocyte maturation", "mRNA processing", "mRNA splicing" ]
[ "Repressor", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
10
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 33: Neurons - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
4,835
6
ENSG00000119318
RAD23B
RAD23 homolog B, nucleotide excision repair protein
[ "P54727" ]
9
107283137-107332192
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029718", "HPA029720", "CAB033868" ]
[ "HHR23B", "HR23B", "P58" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Ubl conjugation pathway" ]
[]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
72
No
No
Cluster 24: Non-specific - Transcription
Cluster 16: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
4,836
1
ENSG00000119321
FKBP15
FKBP prolyl isomerase family member 15
[ "Q5T1M5" ]
9
113161006-113221458
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007979" ]
[ "FKBP133", "KIAA0674", "PPP1R76", "WAFL" ]
[ "Predicted intracellular proteins" ]
[ "Endocytosis", "Transport" ]
[ "Actin-binding" ]
[]
[ "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
26
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 43: Non-specific - Basic cellular processes
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 5: Spleen - Immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,837
8
ENSG00000119326
CTNNAL1
Catenin alpha like 1
[ "Q9UBT7" ]
9
108942569-109013522
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "alpha-CATU", "CLLP" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
24
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 23: Choroid plexus - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 18: Adrenal cortex cells - Steroidogensis
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enhanced
Detected in many
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]
4,838
1
ENSG00000119328
ABITRAM
Actin binding transcription modulator
[ "Q9NX38" ]
9
108934400-108950744
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035917", "HPA035918" ]
[ "C9orf6", "CG-8", "FAM206A", "FLJ20457", "Simiate" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Kinetochore", "Cytokinetic bridge", "Mitotic spindle", "Primary cilium", "Primary cilium tip" ]
[]
[]
Approved
Uncertain
null
9
Yes
No
Cluster 10: Non-specific - Membrane trafficking
Cluster 23: Choroid plexus - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,839
5
ENSG00000119333
DYNC2I2
Dynein 2 intermediate chain 2
[ "Q96EX3" ]
9
128633653-128656847
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040764", "HPA041091" ]
[ "bA216B9.3", "CFAP133", "DIC5", "FAP133", "MGC20486", "WDR34" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Ciliopathy", "Disease variant" ]
[ "Nucleoplasm", "Centrosome", "Basal body" ]
[ "Nucleoli", "Nuclear bodies", "Primary cilium", "Cytosol" ]
[]
[]
Supported
Approved
null
35
null
Yes
Cluster 17: B-cells - Immunoglobulins
Cluster 3: Choroid plexus - Cilium
Cluster 43: Non-specific - Basic cellular processes
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
4
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
4,840
1
ENSG00000119335
SET
SET nuclear proto-oncogene
[ "Q01105" ]
9
128683424-128696400
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005232", "HPA063683" ]
[ "2PP2A", "IGAAD", "IPP2A2", "PHAPII", "TAF-I", "TAF-IBETA" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[ "Chaperone", "DNA-binding" ]
[ "Cancer-related genes", "Disease variant", "Intellectual disability", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[ "Lipid droplets" ]
[]
[]
Enhanced
Supported
null
65
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 13: Oligodendrocytes - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 17: Non-specific - RNA processing
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,841
7
ENSG00000119383
PTPA
Protein phosphatase 2 phosphatase activator
[ "Q15257" ]
9
129110950-129148946
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005695", "CAB022068", "CAB035999", "CAB080052", "CAB080054", "CAB080098" ]
[ "PPP2R4", "PR53" ]
[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Isomerase", "Rotamase" ]
[ "Disease variant", "Intellectual disability", "Neurodegeneration", "Parkinson disease", "Parkinsonism" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Enhanced
Approved
null
20
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 38: Sub-cortical - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
4,842
8
ENSG00000119392
GLE1
GLE1 RNA export mediator
[ "Q53GS7" ]
9
128504655-128543874
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041689", "HPA043538", "HPA061560" ]
[ "GLE1L", "hGLE1", "LCCS1" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[ "mRNA transport", "Protein transport", "Translocation", "Transport" ]
[]
[ "Disease variant" ]
[ "Nuclear membrane" ]
[ "Nucleoli", "Cytosol" ]
[]
[]
Supported
Supported
null
56
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 31: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,843
4
ENSG00000119396
RAB14
RAB14, member RAS oncogene family
[ "P61106" ]
9
121178133-121223014
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026419", "CAB037066" ]
[ "FBP", "RAB-14" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[ "Hydrolase" ]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Approved
null
83
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 28: Oligodendrocytes - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 17: Non-specific - RNA processing
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,844
1
ENSG00000119397
CNTRL
Centriolin
[ "Q7Z7A1" ]
9
121074660-121177729
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020468", "HPA020480", "HPA051583" ]
[ "CEP1", "CEP110" ]
[ "Cancer-related genes", "Disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division" ]
[]
[ "Cancer-related genes" ]
[ "Centrosome", "Basal body", "Flagellar centriole" ]
[ "Golgi apparatus", "Plasma membrane", "Centriolar satellite", "Cytosol" ]
[]
[]
Supported
Approved
null
5
null
Yes
Cluster 22: Eosinophils - Transcription
Cluster 6: Non-specific - Immune response
Cluster 43: Non-specific - Basic cellular processes
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 51: Lymphoid tissue - Adaptive immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Head and Neck Squamous Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Rectum Adenocarcinoma" ]
4,845
3
ENSG00000119401
TRIM32
Tripartite motif containing 32
[ "Q13049" ]
9
116687305-116701300
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050060" ]
[ "BBS11", "HT2A", "LGMD2H", "TATIP" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[ "Bardet-Biedl syndrome", "Ciliopathy", "Disease variant", "Intellectual disability", "Limb-girdle muscular dystrophy", "Obesity" ]
[ "Intermediate filaments" ]
[]
[]
[]
Approved
Approved
null
95
No
No
Cluster 39: T-cells - T-cell receptor
Cluster 5: Non-specific - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 101: Choroid plexus epithelial cells - Ion transport
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,846
3
ENSG00000119402
FBXW2
F-box and WD repeat domain containing 2
[ "Q9UKT8" ]
9
120751978-120793416
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA067878" ]
[ "FBW2", "Fwd2", "Md6" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
22
null
null
Cluster 41: Basophils - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 43: Non-specific - Basic cellular processes
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,847
7
ENSG00000119403
PHF19
PHD finger protein 19
[ "Q5T6S3" ]
9
120855651-120894896
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "DKFZP727G051", "MTF2L1", "PCL3", "TDRD19B" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Repressor" ]
[]
[]
[]
[]
[]
null
null
null
56
null
null
Cluster 33: Non-specific - ATP binding
Cluster 11: White matter - Signal transduction
Cluster 43: Non-specific - Basic cellular processes
Cluster 27: Non-specific - Cell proliferation
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in all
4
4
2
3
[]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
4,848
4
ENSG00000119408
NEK6
NIMA related kinase 6
[ "Q9HC98" ]
9
124257606-124353307
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB045993", "HPA056828" ]
[ "SID6-1512" ]
[ "Enzymes", "Predicted intracellular proteins", "Transporters" ]
[ "Apoptosis", "Cell cycle", "Cell division", "Chromosome partition", "Mitosis" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Centriolar satellite" ]
[]
[]
Supported
Approved
null
48
null
null
Cluster 29: Non-specific - Unknown function
Cluster 39: Astrocytes - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 36: Brain & Liver - Signaling
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
5
0
5
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
4,849
8
ENSG00000119411
BSPRY
B-box and SPRY domain containing
[ "Q5W0U4" ]
9
113349541-113371233
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA042889", "HPA077485" ]
[ "FLJ20150" ]
[ "Predicted intracellular proteins" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Uncertain
Approved
null
4
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 33: Neurons - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 69: Parathyroid gland - Mixed function
Tissue enriched
Detected in many
5
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
21
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
4,850
5
ENSG00000119414
PPP6C
Protein phosphatase 6 catalytic subunit
[ "O00743" ]
9
125146573-125189939
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA050940" ]
[ "PP6" ]
[ "Cancer-related genes", "Enzymes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Immunity", "Innate immunity" ]
[ "Hydrolase", "Protein phosphatase" ]
[ "Cancer-related genes" ]
[]
[]
[]
[]
null
Uncertain
null
59
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 55: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,851
7
ENSG00000119421
NDUFA8
NADH:ubiquinone oxidoreductase subunit A8
[ "P51970" ]
9
122144058-122159779
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041510", "HPA041600" ]
[ "MGC793", "PGIV" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[]
[ "Disease variant", "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[ "Mid piece", "Principal piece", "End piece" ]
[]
[]
Supported
Enhanced
null
28
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 43: Non-specific - Basic cellular processes
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
4,852
1
ENSG00000119431
HDHD3
Haloacid dehalogenase like hydrolase domain containing 3
[ "Q9BSH5" ]
9
113373419-113376986
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020427", "HPA024158", "HPA024585" ]
[ "C9orf158", "MGC12904" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoli" ]
[ "Vesicles" ]
[]
[]
Enhanced
Enhanced
null
17
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 33: Neurons - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 26: Kidney & Intestine - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
4,853
9
ENSG00000119446
RBM18
RNA binding motif protein 18
[ "Q96H35" ]
9
122237622-122264840
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA057281", "HPA077955" ]
[ "MGC2734" ]
[ "Predicted intracellular proteins" ]
[]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Cytokinetic bridge", "Cytosol" ]
[]
[]
Enhanced
Uncertain
null
2
Yes
No
Cluster 45: Eosinophils - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 62: Skeletal muscle - Muscle contraction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
4,854
9
ENSG00000119457
SLC46A2
Solute carrier family 46 member 2
[ "Q9BY10" ]
9
112878920-112890876
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA020098" ]
[ "Ly110", "TSCOT" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Immunity", "Innate immunity", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 15: Non-specific - Transcription
Cluster 56: Non-specific - Sensory perception
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enriched
Detected in single
5
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
4,855
1
ENSG00000119471
HSDL2
Hydroxysteroid dehydrogenase like 2
[ "Q6YN16" ]
9
112380080-112472405
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042890", "HPA050453" ]
[ "C9orf99", "SDR13C1" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Oxidoreductase" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Enhanced
Enhanced
null
12
null
null
Cluster 41: Basophils - Unknown function
Cluster 39: Astrocytes - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,856
7
ENSG00000119487
MAPKAP1
MAPK associated protein 1
[ "Q9BPZ7" ]
9
125437393-125707234
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029091", "HPA029092" ]
[ "MGC2745", "MIP1", "SIN1" ]
[ "Predicted intracellular proteins" ]
[ "Stress response" ]
[]
[]
[ "Nucleoplasm" ]
[ "Primary cilium", "Cytosol" ]
[]
[]
Approved
Supported
null
29
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 27: Non-specific - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 7: Non-specific - Transcription
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,857
6
ENSG00000119508
NR4A3
Nuclear receptor subfamily 4 group A member 3
[ "Q92570" ]
9
99821855-99866891
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043360" ]
[ "CHN", "CSMF", "MINOR", "NOR1" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Nuclear receptors", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Receptor" ]
[ "Cancer-related genes", "Proto-oncogene" ]
[]
[]
[]
[]
null
Uncertain
null
33
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 103: Non-specific - Basic cellular processes
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Group enriched
Detected in some
5
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Rectum Adenocarcinoma", "Skin Cutaneous Melanoma" ]
[ "Stomach Adenocarcinoma" ]
[ "Rectum Adenocarcinoma", "Skin Cutaneous Melanoma", "Stomach Adenocarcinoma" ]
4,858
7
ENSG00000119509
INVS
Inversin
[ "Q9Y283" ]
9
100099243-100302175
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA049994" ]
[ "NPHP2" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Wnt signaling pathway" ]
[ "Calmodulin-binding", "Developmental protein" ]
[ "Ciliopathy", "Disease variant", "Nephronophthisis" ]
[ "Primary cilium", "Cytosol" ]
[ "Centrosome", "Basal body" ]
[]
[]
Approved
null
null
4
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 11: White matter - Signal transduction
Cluster 43: Non-specific - Basic cellular processes
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
4,859
4
ENSG00000119514
GALNT12
Polypeptide N-acetylgalactosaminyltransferase 12
[ "Q8IXK2" ]
9
98807670-98850081
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048292", "HPA071076" ]
[ "GalNAc-T12" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[ "Disease variant" ]
[ "Plasma membrane" ]
[ "Nucleoplasm", "Cell Junctions" ]
[]
[]
Approved
Enhanced
null
25
null
null
Cluster 22: Eosinophils - Transcription
Cluster 50: Non-specific - Nucleic acid binding
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 17: Intestine - Digestion
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,860
5
ENSG00000119522
DENND1A
DENN domain containing 1A
[ "Q8TEH3" ]
9
123379654-123930152
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA020481" ]
[ "FAM31A", "FLJ21129", "KIAA1608" ]
[ "Disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Protein transport", "Transport" ]
[ "Guanine-nucleotide releasing factor" ]
[]
[ "Vesicles", "Cytosol" ]
[]
[]
[]
Approved
null
null
13
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 51: Neurons - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 46: Brain & retina - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
4,861
1
ENSG00000119523
ALG2
ALG2 alpha-1,3/1,6-mannosyltransferase
[ "Q9H553" ]
9
99216425-99221942
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041512", "HPA041601" ]
[ "CDG1I", "CDGIi", "FLJ14511", "hALPG2", "NET38" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[ "Congenital disorder of glycosylation", "Congenital myasthenic syndrome", "Disease variant" ]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
Approved
null
13
null
No
Cluster 13: Non-specific - Mitochondria
Cluster 50: Non-specific - Nucleic acid binding
Cluster 43: Non-specific - Basic cellular processes
Cluster 8: Non-specific - Secretory pathway
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,862
6
ENSG00000119535
CSF3R
Colony stimulating factor 3 receptor
[ "Q99062" ]
1
36466043-36483278
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017116", "HPA048086" ]
[ "CD114", "GCSFR" ]
[ "Cancer-related genes", "CD markers", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[ "Receptor" ]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets" ]
[]
[]
[ "Intracellular and membrane" ]
[ "Receptor" ]
null
Enhanced
null
7
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 12: Non-specific - Vasculature
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
25
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
5
Immune cell enriched
Detected in many
7
1
0
1
[]
[ "Testicular Germ Cell Tumor" ]
[ "Testicular Germ Cell Tumor" ]
4,863
2
ENSG00000119537
KDSR
3-ketodihydrosphingosine reductase
[ "Q06136" ]
18
63327726-63367228
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB003673", "HPA044884" ]
[ "DHSR", "FVT1", "SDR35C1" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism", "Sphingolipid metabolism" ]
[ "Oxidoreductase" ]
[ "Cancer-related genes", "Disease variant", "Palmoplantar keratoderma", "Proto-oncogene" ]
[]
[]
[]
[]
null
Approved
null
31
null
null
Cluster 33: Non-specific - ATP binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 55: Breast - Lactation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
4,864
7
ENSG00000119547
ONECUT2
One cut homeobox 2
[ "O95948" ]
18
57435374-57491298
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA057058" ]
[ "OC-2" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Actin filaments" ]
[]
[]
Supported
Enhanced
null
null
null
null
null
Cluster 33: Neurons - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in some
5
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
4,866
4
ENSG00000119559
C19orf25
Chromosome 19 open reading frame 25
[ "Q9UFG5" ]
19
1461143-1479219
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050270", "HPA067491" ]
[ "FLJ36666" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Intermediate filaments" ]
[]
[]
[]
Approved
Approved
null
45
No
No
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 27: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 65: Non-specific - Cell growth & division
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
4,867
8
ENSG00000119574
ZBTB45
Zinc finger and BTB domain containing 45
[ "Q96K62" ]
19
58513530-58538911
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035754", "HPA075485" ]
[ "FLJ14486", "ZNF499" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Cytosol" ]
[ "Nuclear bodies" ]
[]
[]
Uncertain
Uncertain
null
1
null
null
Cluster 25: Non-specific - Unknown function
Cluster 32: Cerebral cortex - Mixed function
Cluster 60: Prostate cancer - Unknown function
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Prostate Adenocarcinoma" ]
[ "Prostate Adenocarcinoma" ]
4,868
6
ENSG00000119596
YLPM1
YLP motif containing 1
[ "P49750" ]
14
74763316-74859435
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA048070", "HPA061123" ]
[ "C14orf170", "PPP1R169", "ZAP" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Repressor" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Supported
Uncertain
null
43
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 30: Non-specific - Gene expression regulation
Cluster 7: Non-specific - Transcription
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,869
7
ENSG00000119599
DCAF4
DDB1 and CUL4 associated factor 4
[ "Q8WV16" ]
14
72926377-72959703
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047276" ]
[ "DKFZp434K114", "WDR21", "WDR21A" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
21
null
null
Cluster 18: Non-specific - Translation
Cluster 24: Neurons - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
4,870
1
ENSG00000119614
VSX2
Visual system homeobox 2
[ "P58304" ]
14
74239449-74262738
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003436" ]
[ "CHX10", "HOX10", "RET1" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Sensory transduction", "Transcription", "Transcription regulation", "Vision" ]
[ "Activator", "Developmental protein", "DNA-binding", "Repressor" ]
[ "Cataract", "Disease variant", "Microphthalmia" ]
[]
[]
[]
[]
null
Enhanced
null
20
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 55: Lymphoma - Immune response
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in single
254
Not detected
Not detected
null
Cancer enriched
Detected in single
26
Group enriched
Detected in some
53
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,872
2
ENSG00000119616
FCF1
FCF1 rRNA-processing protein
[ "Q9Y324" ]
14
74713144-74738620
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA046681" ]
[ "Bka", "C14orf111", "CGI-35", "UTP24" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Ribosome biogenesis", "rRNA processing" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
12
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 28: Oligodendrocytes - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
4,873
4
ENSG00000119630
PGF
Placental growth factor
[ "P49763" ]
14
74941834-74955626
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041624" ]
[ "D12S1900", "PGFL", "PIGF", "PLGF", "PlGF-2", "SHGC-10760" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "FDA approved drug targets", "Plasma proteins", "Predicted secreted proteins", "RAS pathway related proteins" ]
[ "Angiogenesis", "Differentiation" ]
[ "Developmental protein", "Growth factor", "Heparin-binding", "Mitogen" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[ "Nucleoplasm" ]
[ "Mitochondria", "Cytosol" ]
[ "Secreted to blood" ]
[ "Growth factor" ]
Approved
null
null
2
No
No
null
Cluster 44: Non-specific - Mixed function
Cluster 34: Testis cancer - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Group enriched
Detected in many
7
Not detected in immune cells
Not detected
null
4
0
4
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
4,874
8
ENSG00000119632
IFI27L2
Interferon alpha inducible protein 27 like 2
[ "Q9H2X8" ]
14
94127779-94130253
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA049588" ]
[ "FAM14A", "TLH29" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Cytosol" ]
[ "Nucleoli" ]
[ "Intracellular and membrane" ]
[ "Other" ]
Approved
null
null
null
No
No
Cluster 5: Non-specific - Cell proliferation
Cluster 27: Non-specific - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 47: Platelets - Hemostasis
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
4,875
4
ENSG00000119636
BBOF1
Basal body orientation factor 1
[ "Q8ND07" ]
14
74019349-74082863
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA003090", "HPA003136", "HPA075108" ]
[ "C14orf45", "CCDC176", "FBB10" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane", "Centriolar satellite", "Cytosol" ]
[]
[]
Approved
Approved
null
1
null
null
Cluster 41: Basophils - Unknown function
Cluster 17: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
4,876
5
ENSG00000119640
ACYP1
Acylphosphatase 1
[ "P07311" ]
14
75053237-75069483
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA034944" ]
[]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 26: Oligodendrocytes - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
4,878
9
ENSG00000119650
IFT43
Intraflagellar transport 43
[ "Q96FT9" ]
14
75902136-76084585
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003438" ]
[ "C14orf179", "FLJ32173", "MGC16028" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[]
[ "Ciliopathy", "Disease variant", "Ectodermal dysplasia", "Retinitis pigmentosa" ]
[ "Microtubules", "Primary cilium", "Principal piece", "End piece" ]
[ "Cytokinetic bridge", "Mitotic spindle", "Centriolar satellite", "Basal body", "Perinuclear theca" ]
[]
[]
Supported
Approved
null
27
Yes
null
Cluster 5: Non-specific - Cell proliferation
Cluster 3: Choroid plexus - Cilium
Cluster 30: Non-specific - Gene expression regulation
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
4,879
3
ENSG00000119655
NPC2
NPC intracellular cholesterol transporter 2
[ "P61916" ]
14
74476192-74494177
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000835", "CAB032888" ]
[ "EDDM1", "HE1", "NP-C2" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted secreted proteins", "Transporters" ]
[ "Cholesterol metabolism", "Lipid metabolism", "Lipid transport", "Steroid metabolism", "Sterol metabolism", "Transport" ]
[]
[ "Disease variant", "Niemann-Pick disease" ]
[]
[]
[ "Secreted to blood" ]
[ "Transport" ]
null
Enhanced
null
11
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 21: Non-specific - Metabolism
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 50: Epididymis - Male reproductive secretion
Tissue enriched
Detected in all
9
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in all
14
Group enriched
Detected in all
4
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
4,880
5
ENSG00000119661
DNAL1
Dynein axonemal light chain 1
[ "Q4LDG9" ]
14
73644875-73703732
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053129", "HPA060974" ]
[ "1700010H15RiK", "C14orf168", "CILD16", "MGC12435" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Motor protein" ]
[ "Ciliopathy", "Disease variant", "Kartagener syndrome", "Primary ciliary dyskinesia" ]
[ "Nucleoplasm", "Basal body", "Cytosol", "Principal piece" ]
[ "Centriolar satellite", "Centrosome", "Acrosome", "Mid piece", "End piece" ]
[]
[]
Approved
Approved
null
2
null
null
Cluster 14: Non-specific - Unknown function
Cluster 29: Forebrain - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
4,881
9
ENSG00000119669
IRF2BPL
Interferon regulatory factor 2 binding protein like
[ "Q9H1B7" ]
14
77024543-77028708
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050862", "HPA061333" ]
[ "C14orf4", "EAP1", "KIAA1865" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Transferase" ]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Enhanced
Approved
null
14
null
Yes
Cluster 30: Non-specific - DNA binding
Cluster 46: Brainstem - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
4,882
5
ENSG00000119673
ACOT2
Acyl-CoA thioesterase 2
[ "P49753" ]
14
73567620-73575658
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043705", "HPA060170" ]
[ "Mte1", "ZAP128" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Fatty acid metabolism", "Lipid metabolism" ]
[ "Hydrolase", "Serine esterase" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Enhanced
null
7
null
null
Cluster 33: Non-specific - ATP binding
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 30: Non-specific - Gene expression regulation
Cluster 15: Non-specific - Protein processing
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Stomach Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Stomach Adenocarcinoma" ]
4,883
7
ENSG00000119681
LTBP2
Latent transforming growth factor beta binding protein 2
[ "Q14767" ]
14
74498183-74612378
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003415" ]
[ "C14orf141", "LTBP3" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Growth factor binding", "Heparin-binding" ]
[ "Disease variant", "Dwarfism", "Glaucoma" ]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "Other" ]
null
Supported
null
1
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 8: Immune cells - Immune response
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enriched
Detected in many
5
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
4,884
5
ENSG00000119684
MLH3
MutL homolog 3
[ "Q9UHC1" ]
14
75013769-75051532
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA060570" ]
[]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[]
[ "Disease variant", "Hereditary nonpolyposis colorectal cancer" ]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
6
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 28: Oligodendrocytes - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 47: Platelets - Hemostasis
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
4,886
2
ENSG00000119685
TTLL5
Tubulin tyrosine ligase like 5
[ "Q6EMB2" ]
14
75633625-75955079
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA032128" ]
[ "KIAA0998", "STAMP" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Transcription" ]
[ "Ligase" ]
[ "Cone-rod dystrophy", "Disease variant" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
4
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 30: White matter - Myelination
Cluster 30: Non-specific - Gene expression regulation
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 47: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
4,887
8
ENSG00000119688
ABCD4
ATP binding cassette subfamily D member 4
[ "O14678" ]
14
74285269-74303055
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003396" ]
[ "EST352188", "P70R", "PMP69", "PXMP1L" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[ "Translocase" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
3
null
null
Cluster 32: Basophils - Transcription
Cluster 25: Non-specific - Transcription
Cluster 30: Non-specific - Gene expression regulation
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 26: Kidney & Intestine - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Rectum Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
4,889
7
ENSG00000119689
DLST
Dihydrolipoamide S-succinyltransferase
[ "P36957" ]
14
74881891-74903743
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003010" ]
[ "DLTS", "KGD2", "OGDC-E2" ]
[ "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Tricarboxylic acid cycle" ]
[ "Acyltransferase", "Transferase" ]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Mitochondria", "Cytosol" ]
[]
[]
Supported
Supported
null
85
null
null
Cluster 41: Basophils - Unknown function
Cluster 42: Choroid plexus - Mitochondria
Cluster 30: Non-specific - Gene expression regulation
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
4,890
5
ENSG00000119698
PPP4R4
Protein phosphatase 4 regulatory subunit 4
[ "Q6NUP7" ]
14
94146128-94279734
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041866", "HPA050321" ]
[ "CFAP14", "KIAA1622", "PP4R4" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[ "Primary cilium", "Basal body" ]
[]
[]
Supported
Approved
null
7
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 73: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,891
3
ENSG00000119699
TGFB3
Transforming growth factor beta 3
[ "P10600" ]
14
75958097-75983011
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027923" ]
[ "ARVD", "ARVD1" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted secreted proteins" ]
[]
[ "Growth factor", "Mitogen" ]
[ "Cancer-related genes", "Cardiomyopathy", "Disease variant" ]
[ "Vesicles" ]
[ "Nucleoplasm", "Centriolar satellite", "Basal body" ]
[ "Secreted to blood" ]
[ "Growth factor" ]
Approved
null
null
4
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 27: Breast cancer - Unknown function
Cluster 108: Fibroblasts - ECM organization
Cluster 43: Placenta - Pregnancy hormone signaling
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
4,892
1
ENSG00000119703
ZC2HC1C
Zinc finger C2HC-type containing 1C
[ "Q53FD0" ]
14
75064109-75119502
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050928", "HPA065062" ]
[ "C14orf140", "FAM164C" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nuclear speckles" ]
[ "Mitochondria" ]
[]
[]
Approved
Enhanced
null
19
No
No
null
Cluster 3: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 22: Epididymis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
4,893
2
ENSG00000119705
SLIRP
SRA stem-loop interacting RNA binding protein
[ "Q9GZT3" ]
14
77708071-77761104
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA020291" ]
[ "C14orf156", "DC50" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "Repressor", "RNA-binding" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Supported
Approved
null
31
No
Yes
Cluster 2: Dendritic cells - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 30: Non-specific - Gene expression regulation
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Lung Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Lung Adenocarcinoma" ]
4,894
4
ENSG00000119711
ALDH6A1
Aldehyde dehydrogenase 6 family member A1
[ "Q02252" ]
14
74056847-74084492
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029072", "HPA029073", "HPA029074", "HPA029075" ]
[ "MMSDH" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Oxidoreductase" ]
[ "Disease variant" ]
[ "Mitochondria" ]
[]
[]
[]
Enhanced
Enhanced
null
1
No
No
Cluster 41: Basophils - Unknown function
Cluster 39: Astrocytes - Mixed function
Cluster 60: Prostate cancer - Unknown function
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 76: Non-specific - Metabolism
Group enriched
Detected in all
5
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
4,896
2
ENSG00000119715
ESRRB
Estrogen related receptor beta
[ "O95718" ]
14
76310712-76501837
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA074772" ]
[ "DFNB35", "ERR2", "ERRb", "ERRbeta", "ESRL2", "NR3B2" ]
[ "Disease related genes", "Human disease related genes", "Nuclear receptors", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "Receptor" ]
[ "Deafness", "Disease variant", "Non-syndromic deafness" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
null
null
4
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 12: Bone cancer - Neuronal signaling
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Group enriched
Detected in some
4
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in single
5
Group enriched
Detected in many
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
4,898
5
ENSG00000119718
EIF2B2
Eukaryotic translation initiation factor 2B subunit beta
[ "P49770" ]
14
75002921-75012366
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005841", "CAB037105", "HPA048028" ]
[ "EIF-2Bbeta", "EIF2B", "EIF2Bbeta" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Protein biosynthesis" ]
[ "Initiation factor" ]
[ "Disease variant", "Leukodystrophy" ]
[ "Plasma membrane", "Focal adhesion sites" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
41
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 30: Non-specific - Gene expression regulation
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
4,899
3
ENSG00000119720
NRDE2
NRDE-2, necessary for RNA interference, domain containing
[ "Q9H7Z3" ]
14
90267860-90331969
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047050", "HPA050583" ]
[ "C14orf102", "FLJ14051" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "DNA damage", "Mitosis", "mRNA processing", "mRNA splicing" ]
[]
[]
[ "Nucleoplasm", "Mitochondria" ]
[]
[]
[]
Supported
Uncertain
null
9
null
null
Cluster 20: Non-specific - DNA binding
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 30: Non-specific - Gene expression regulation
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
4,900
5
ENSG00000119723
COQ6
Coenzyme Q6, monooxygenase
[ "Q9Y2Z9" ]
14
73949926-73963670
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA051371" ]
[ "CGI-10" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Ubiquinone biosynthesis" ]
[ "Monooxygenase", "Oxidoreductase" ]
[ "Deafness", "Disease variant", "Primary mitochondrial disease" ]
[]
[]
[]
[]
null
Uncertain
null
17
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 21: Non-specific - Metabolism
Cluster 30: Non-specific - Gene expression regulation
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
4,901
7
ENSG00000119725
ZNF410
Zinc finger protein 410
[ "Q86VK4" ]
14
73886617-73932521
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003610" ]
[ "APA-1", "APA1" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
null
null
12
null
No
Cluster 42: Non-specific - Vesicular transport
Cluster 55: Non-specific - Transcription
Cluster 30: Non-specific - Gene expression regulation
Cluster 22: Non-specific - Basic cellular functions
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
4,902
2
ENSG00000119729
RHOQ
Ras homolog family member Q
[ "P17081" ]
2
46541806-46584688
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA044938" ]
[ "ARHQ", "RASL7A", "TC10" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles", "Cytosol" ]
[]
[]
[]
Approved
null
null
13
No
No
Cluster 2: Dendritic cells - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 103: Non-specific - Basic cellular processes
Cluster 41: Striated muscle - Muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Group enriched
Detected in many
4
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
4,903
5
ENSG00000119771
KLHL29
Kelch like family member 29
[ "Q96CT2" ]
2
23385179-23708611
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035237", "HPA049057", "HPA057379" ]
[ "KBTBD9", "KIAA1921" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
8
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 33: Sarcoma - Muscle contraction
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
4,906
3
ENSG00000119772
DNMT3A
DNA methyltransferase 3 alpha
[ "Q9Y6K1" ]
2
25227855-25342590
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009469", "HPA026588" ]
[]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "Chromatin regulator", "DNA-binding", "Methyltransferase", "Repressor", "Transferase" ]
[ "Cancer-related genes", "Disease variant", "Dwarfism", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Supported
Approved
null
57
null
null
Cluster 22: Eosinophils - Transcription
Cluster 37: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 7: Non-specific - Transcription
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Bladder Urothelial Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
4,907
9
ENSG00000119777
TMEM214
Transmembrane protein 214
[ "Q6NUQ4" ]
2
27032910-27041694
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034551" ]
[ "FLJ20254" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Apoptosis" ]
[]
[]
[ "Endoplasmic reticulum", "Golgi apparatus", "Cytosol" ]
[]
[]
[]
Supported
null
null
6
null
null
Cluster 32: Basophils - Transcription
Cluster 44: Non-specific - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 8: Non-specific - Secretory pathway
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
4,908
7