ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000120658 | ENOX1 | Ecto-NOX disulfide-thiol exchanger 1 | [
"Q8TC92"
] | 13 | 43213130-43786972 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038355"
] | [
"cCNOX",
"CNOX",
"FLJ10094",
"PIG38"
] | [
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Electron transport",
"Transport"
] | [
"Oxidoreductase"
] | [] | [
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"Transport"
] | Supported | Approved | null | 6 | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 33: Sarcoma - Muscle contraction | Cluster 82: Dendritic cells - Antigen presentation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 5,018 | 7 |
ENSG00000120659 | TNFSF11 | TNF superfamily member 11 | [
"O14788"
] | 13 | 42562736-42608013 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009193",
"HPA045142"
] | [
"CD254",
"ODF",
"OPGL",
"RANKL",
"TRANCE"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Differentiation"
] | [
"Cytokine",
"Developmental protein",
"Receptor"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets",
"Osteopetrosis"
] | [] | [] | [
"Secreted to blood"
] | [
"Cytokine"
] | null | Enhanced | null | 4 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 4 | Immune cell enriched | Detected in some | 8 | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 5,019 | 6 |
ENSG00000120662 | MTRF1 | Mitochondrial translation release factor 1 | [
"O75570"
] | 13 | 41216369-41263577 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043316"
] | [
"MGC47721",
"MTTRF1",
"RF1"
] | [
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 2 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 5: Non-specific - Mixed function | Cluster 19: Non-specific - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,020 | 4 |
ENSG00000120669 | SOHLH2 | Spermatogenesis and oogenesis specific basic helix-loop-helix 2 | [
"Q9NX45"
] | 13 | 36168217-36214588 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA029182"
] | [
"bHLHe81",
"FLJ20449",
"SPATA28",
"TEB1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Oogenesis",
"Spermatogenesis",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | null | null | null | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 41: Oocytes - Oogenesis | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 5 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,021 | 1 |
ENSG00000120675 | DNAJC15 | DnaJ heat shock protein family (Hsp40) member C15 | [
"Q9Y5T4"
] | 13 | 43023203-43114213 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"DNAJD1",
"MCJ"
] | [
"Disease related genes",
"Predicted membrane proteins"
] | [
"Protein transport",
"Translocation",
"Transport"
] | [
"Chaperone"
] | [] | [] | [] | [] | [] | null | null | null | 10 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 19: Astrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma"
] | 5,022 | 1 |
ENSG00000120685 | PROSER1 | Proline and serine rich 1 | [
"Q86XN7"
] | 13 | 39009865-39038089 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB034225",
"HPA055687"
] | [
"bA50D16.2",
"C13orf23",
"FLJ12661"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 19: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,023 | 1 |
ENSG00000120686 | UFM1 | Ubiquitin fold modifier 1 | [
"P61960"
] | 13 | 38349849-38363619 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039758"
] | [
"bA131P10.1",
"C13orf20"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"Leukodystrophy"
] | [] | [] | [] | [] | null | Approved | null | 26 | null | null | Cluster 32: Basophils - Transcription | Cluster 7: Non-specific - Ribosome | Cluster 19: Non-specific - Unknown function | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,024 | 9 |
ENSG00000120688 | WBP4 | WW domain binding protein 4 | [
"O75554"
] | 13 | 41061509-41084006 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038965",
"HPA058738"
] | [
"FBP21",
"MGC117310"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 37 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 19: Non-specific - Unknown function | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,025 | 6 |
ENSG00000120690 | ELF1 | E74 like ETS transcription factor 1 | [
"P32519"
] | 13 | 40931924-41061440 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001755",
"CAB005172"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | 7 | null | null | Cluster 46: Basophils - Proteolysis | Cluster 30: White matter - Myelination | Cluster 46: Lymphoma - Humoral immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,026 | 4 |
ENSG00000120693 | SMAD9 | SMAD family member 9 | [
"O15198"
] | 13 | 36844831-36920765 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009119",
"HPA031162"
] | [
"MADH6",
"MADH9",
"SMAD8",
"SMAD8/9"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Enhanced | Approved | null | 15 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 38: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Thyroid Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Thyroid Carcinoma"
] | 5,027 | 1 |
ENSG00000120694 | HSPH1 | Heat shock protein family H (Hsp110) member 1 | [
"Q92598"
] | 13 | 31134973-31162388 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002060",
"HPA028675",
"HPA031569"
] | [
"HSP105A",
"HSP105B",
"KIAA0201",
"NY-CO-25"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Stress response"
] | [] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Enhanced | Uncertain | null | 78 | No | Yes | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 19: Non-specific - Unknown function | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 78: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,028 | 2 |
ENSG00000120696 | KBTBD7 | Kelch repeat and BTB domain containing 7 | [
"Q8WVZ9"
] | 13 | 41189834-41194569 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043709",
"HPA046861",
"HPA048914"
] | [
"DKFZP434E2318"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Signal transduction inhibitor"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 96 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 55: Non-specific - Transcription | Cluster 19: Non-specific - Unknown function | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Rectum Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 5,029 | 5 |
ENSG00000120697 | ALG5 | ALG5 dolichyl-phosphate beta-glucosyltransferase | [
"Q9Y673"
] | 13 | 36949738-37000763 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007989"
] | [
"bA421P11.2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | No | No | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 19: Non-specific - Unknown function | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,030 | 1 |
ENSG00000120699 | EXOSC8 | Exosome component 8 | [
"Q96B26"
] | 13 | 36998816-37025881 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB034240",
"HPA039702",
"HPA043942",
"HPA075230"
] | [
"bA421P11.3",
"CIP3",
"EAP2",
"OIP2",
"p9",
"RRP43",
"Rrp43p"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [
"RNA-binding"
] | [
"Disease variant",
"Neurodegeneration"
] | [
"Nucleoli fibrillar center",
"Mitotic chromosome"
] | [
"Nucleoplasm",
"Vesicles",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 96 | Yes | null | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 19: Non-specific - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Bladder Urothelial Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,031 | 3 |
ENSG00000120705 | ETF1 | Eukaryotic translation termination factor 1 | [
"P62495"
] | 5 | 138506095-138543236 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011686",
"HPA037511"
] | [
"ERF",
"ERF1",
"RF1",
"SUP45L1",
"TB3-1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Nonsense-mediated mRNA decay",
"Protein biosynthesis"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 19 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 21: Non-specific - Metabolism | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Thyroid Carcinoma"
] | 5,032 | 5 |
ENSG00000120708 | TGFBI | Transforming growth factor beta induced | [
"Q15582"
] | 5 | 136028988-136063818 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008612",
"HPA017019"
] | [
"BIGH3",
"CDB1",
"CDGG1",
"CSD1",
"CSD2",
"CSD3",
"LCD1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion",
"Sensory transduction",
"Vision"
] | [] | [
"Amyloidosis",
"Corneal dystrophy",
"Disease variant"
] | [] | [] | [
"Secreted to blood"
] | [
"Cell adhesion"
] | null | Enhanced | null | 6 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 15: Kidney cancer - Membrane components | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 32 | 4 | 0 | 4 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 5,033 | 2 |
ENSG00000120709 | FAM53C | Family with sequence similarity 53 member C | [
"Q9NYF3"
] | 5 | 138331935-138349729 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042796"
] | [
"C5orf6"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 33 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 38: Sub-cortical - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Immune cell enriched | Detected in many | 5 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,034 | 5 |
ENSG00000120725 | SIL1 | SIL1 nucleotide exchange factor | [
"Q9H173"
] | 5 | 138946724-139293557 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011949"
] | [
"BAP",
"MSS",
"ULG5"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Translocation",
"Transport"
] | [] | [
"Disease variant"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Transport"
] | null | Enhanced | null | 25 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 36: Choroid plexus - Mixed function | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | 5,035 | 4 |
ENSG00000120727 | PAIP2 | Poly(A) binding protein interacting protein 2 | [
"Q9BPZ3"
] | 5 | 139341587-139369720 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035945",
"CAB037212",
"HPA056766"
] | [
"PAIP2A"
] | [
"Predicted intracellular proteins"
] | [
"Translation regulation"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | Approved | null | 20 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,036 | 4 |
ENSG00000120729 | MYOT | Myotilin | [
"Q9UBF9"
] | 5 | 137867858-137887851 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037733",
"HPA037734"
] | [
"LGMD1",
"LGMD1A",
"TTID"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Muscle protein"
] | [
"Disease variant",
"Limb-girdle muscular dystrophy",
"Myofibrillar myopathy"
] | [] | [] | [] | [] | null | Enhanced | null | 7 | null | null | null | Cluster 13: Oligodendrocytes - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in many | 60 | Cancer enriched | Detected in some | 6 | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | 5,037 | 7 |
ENSG00000120733 | KDM3B | Lysine demethylase 3B | [
"Q7LBC6"
] | 5 | 138352685-138437028 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA016610",
"HPA057202"
] | [
"C5orf7",
"JMJD1B",
"KIAA1082",
"NET22"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Dioxygenase",
"Oxidoreductase"
] | [
"Disease variant",
"Dwarfism",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Supported | null | 9 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 39: Astrocytes - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,038 | 4 |
ENSG00000120738 | EGR1 | Early growth response 1 | [
"P18146"
] | 5 | 138465479-138469303 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB019427",
"HPA029937",
"HPA029938"
] | [
"225",
"AT225",
"G0S30",
"KROX-24",
"NGFI-A",
"TIS8",
"ZIF-268"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 16 | No | No | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 15: Non-specific - Transcription | Cluster 64: Connective tissue cells - ECM organization | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | 5,039 | 7 |
ENSG00000120742 | SERP1 | Stress associated endoplasmic reticulum protein 1 | [
"Q9Y6X1"
] | 3 | 150541998-150603228 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038970"
] | [
"FLJ43424",
"RAMP4"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Protein transport",
"Translocation",
"Transport",
"Unfolded protein response"
] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Approved | null | 40 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 7: Non-specific - Ribosome | Cluster 63: Non-specific - Protein processing | Cluster 8: Non-specific - Secretory pathway | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,040 | 8 |
ENSG00000120756 | PLS1 | Plastin 1 | [
"Q14651"
] | 3 | 142596393-142713664 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000895",
"HPA055744",
"HPA061936"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 9 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enriched | Detected in many | 7 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,041 | 2 |
ENSG00000120798 | NR2C1 | Nuclear receptor subfamily 2 group C member 1 | [
"P13056"
] | 12 | 95020229-95073628 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035040",
"HPA035041",
"HPA067767"
] | [
"TR2",
"TR2-11"
] | [
"Nuclear receptors",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Receptor",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Cell Junctions",
"Cytosol"
] | [] | [] | Supported | Supported | null | 21 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 2: Neurons - Nucleosome | Cluster 3: Rhabdoid - Membrane components | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe"
] | 5,043 | 4 |
ENSG00000120800 | UTP20 | UTP20 small subunit processome component | [
"O75691"
] | 12 | 101280105-101386618 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049341"
] | [
"1A6/DRIM",
"DRIM"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"rRNA processing"
] | [] | [] | [
"Nucleoli"
] | [
"Plasma membrane"
] | [] | [] | Supported | null | null | 12 | No | No | Cluster 30: Non-specific - DNA binding | Cluster 11: White matter - Signal transduction | Cluster 38: Non-specific - Transcription | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,044 | 1 |
ENSG00000120802 | TMPO | Thymopoietin | [
"P42166",
"P42167"
] | 12 | 98515579-98550351 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008150",
"CAB009847",
"HPA070805"
] | [
"LAP2",
"LEMD4",
"TP"
] | [
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"DNA-binding"
] | [
"Cardiomyopathy"
] | [
"Nuclear membrane"
] | [] | [] | [] | Enhanced | Enhanced | null | 105 | null | Yes | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 38: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | 5,045 | 6 |
ENSG00000120805 | ARL1 | ADP ribosylation factor like GTPase 1 | [
"P40616"
] | 12 | 101393116-101407772 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062656",
"HPA073012"
] | [
"ARFL1"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Approved | null | 25 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 38: Non-specific - Transcription | Cluster 8: Non-specific - Secretory pathway | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,046 | 3 |
ENSG00000120832 | MTERF2 | Mitochondrial transcription termination factor 2 | [
"Q49AM1"
] | 12 | 106977277-106987160 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003526"
] | [
"FLJ14062",
"MTERFD3"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 4 | null | null | Cluster 11: T-cells - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 10: Ciliated cells - Ion channel activity | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,048 | 6 |
ENSG00000120833 | SOCS2 | Suppressor of cytokine signaling 2 | [
"O14508"
] | 12 | 93569814-93583487 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010356"
] | [
"CIS2",
"Cish2",
"SOCS-2",
"SSI-2",
"SSI2",
"STATI2"
] | [
"Predicted intracellular proteins"
] | [
"Growth regulation",
"Ubl conjugation pathway"
] | [
"Signal transduction inhibitor"
] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Approved | Approved | null | 69 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 44: Non-specific - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 5 | 3 | 4 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,049 | 2 |
ENSG00000120837 | NFYB | Nuclear transcription factor Y subunit beta | [
"P25208"
] | 12 | 104117086-104138241 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004211",
"HPA065646"
] | [
"CBF-A",
"HAP3",
"NF-YB"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 22 | null | null | Cluster 1: T-cells - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 5,050 | 9 |
ENSG00000120860 | WASHC3 | WASH complex subunit 3 | [
"Q9Y3C0"
] | 12 | 102012840-102062149 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038339"
] | [
"CCDC53",
"CGI-116"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 107 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 27: Non-specific - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 6 | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 5,051 | 1 |
ENSG00000120868 | APAF1 | Apoptotic peptidase activating factor 1 | [
"O14727"
] | 12 | 98645290-98735433 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031373",
"CAB069399"
] | [
"APAF-1",
"CED4"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Apoptosis"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Golgi apparatus"
] | [] | [] | Supported | Enhanced | null | 16 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 34: Non-specific - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 5,052 | 5 |
ENSG00000120875 | DUSP4 | Dual specificity phosphatase 4 | [
"Q13115"
] | 8 | 29333064-29350684 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA077183"
] | [
"HVH2",
"MKP-2",
"TYP"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 26 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 29: Forebrain - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 9 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,053 | 1 |
ENSG00000120885 | CLU | Clusterin | [
"P10909"
] | 8 | 27596917-27614700 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000572",
"CAB016253",
"HPA075983",
"CAB080180"
] | [
"APOJ",
"CLI",
"CLU1",
"CLU2",
"KUB1",
"SGP-2",
"SP-40",
"TRPM-2"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Apoptosis",
"Complement pathway",
"Immunity",
"Innate immunity"
] | [
"Chaperone"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Complement pathway"
] | Supported | Enhanced | null | 50 | null | null | Cluster 41: Basophils - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in many | 10 | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 5,054 | 2 |
ENSG00000120889 | TNFRSF10B | TNF receptor superfamily member 10b | [
"O14763"
] | 8 | 23020133-23069031 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023625"
] | [
"CD262",
"DR5",
"KILLER",
"TRAIL-R2",
"TRAILR2",
"TRICK2A",
"TRICKB"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [
"Receptor"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Approved | null | 20 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 12: Non-specific - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme"
] | 5,055 | 2 |
ENSG00000120896 | SORBS3 | Sorbin and SH3 domain containing 3 | [
"O60504"
] | 8 | 22544986-22575788 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA015492",
"HPA015849"
] | [
"SCAM-1",
"SH3D4",
"vinexin"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [] | [] | [
"Cell Junctions"
] | [
"Plasma membrane"
] | [] | [] | Uncertain | Approved | null | 99 | null | null | Cluster 1: T-cells - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Rectum Adenocarcinoma"
] | 5,056 | 3 |
ENSG00000120899 | PTK2B | Protein tyrosine kinase 2 beta | [
"Q14289"
] | 8 | 27311482-27459391 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003850",
"HPA026091",
"HPA026276"
] | [
"CADTK",
"CAKB",
"FAK2",
"PTK",
"PYK2",
"RAFTK"
] | [
"Disease related genes",
"Enzymes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Angiogenesis",
"Immunity"
] | [
"Kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 37 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in all | null | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,057 | 9 |
ENSG00000120903 | CHRNA2 | Cholinergic receptor nicotinic alpha 2 subunit | [
"Q15822"
] | 8 | 27459756-27479883 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048348"
] | [] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Ion transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Cytokinetic bridge"
] | [] | [] | Supported | null | null | null | Yes | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 38: Non-specific - Basic cellular processes | Tissue enriched | Detected in some | 8 | Cancer enriched | Detected in single | 36 | Cancer enriched | Detected in single | 200 | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,058 | 6 |
ENSG00000120907 | ADRA1A | Adrenoceptor alpha 1A | [
"P35348"
] | 8 | 26748150-26867278 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029678",
"HPA029679",
"HPA076693"
] | [
"ADRA1C",
"ADRA1L1"
] | [
"FDA approved drug targets",
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"FDA approved drug targets"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | Approved | Supported | 4 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in single | 7 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 5,059 | 1 |
ENSG00000120910 | PPP3CC | Protein phosphatase 3 catalytic subunit gamma | [
"P48454"
] | 8 | 22440819-22541142 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023396",
"CAB024950",
"HPA074370"
] | [
"CALNA3",
"PP2Bgamma"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding",
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm",
"Calyx"
] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 16: Non-specific - Transcription | Cluster 6: Leukemia - Signal transduction | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,060 | 1 |
ENSG00000120913 | PDLIM2 | PDZ and LIM domain 2 | [
"Q96JY6"
] | 8 | 22578279-22598025 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003880"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Actin filaments",
"Focal adhesion sites"
] | [] | [] | [] | Supported | Approved | null | 3 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 22: Non-specific - Basic cellular functions | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,061 | 5 |
ENSG00000120925 | RNF170 | Ring finger protein 170 | [
"Q96K19"
] | 8 | 42849637-42897290 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050931",
"HPA054621"
] | [
"ADSA",
"DKFZP564A022",
"SNAX1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [] | [] | [] | [] | null | Uncertain | null | 12 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 28: Oligodendrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 5,063 | 4 |
ENSG00000120937 | NPPB | Natriuretic peptide B | [
"P16860"
] | 1 | 11857464-11858945 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA077324"
] | [] | [
"Candidate cardiovascular disease genes",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Hormone",
"Vasoactive",
"Vasodilator"
] | [] | [
"Vesicles"
] | [
"Cytosol"
] | [
"Secreted to blood"
] | [
"Hormone"
] | Approved | null | null | 12 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 35: Non-specific - Mixed function | Tissue enriched | Detected in some | 535 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,064 | 4 |
ENSG00000120942 | UBIAD1 | UbiA prenyltransferase domain containing 1 | [
"Q9Y5Z9"
] | 1 | 11273198-11296049 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044862"
] | [
"SCCD",
"TERE1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Menaquinone biosynthesis",
"Ubiquinone biosynthesis"
] | [
"Prenyltransferase",
"Transferase"
] | [
"Corneal dystrophy",
"Disease variant"
] | [
"Vesicles"
] | [] | [] | [] | Approved | null | null | 45 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 13: Oligodendrocytes - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,065 | 5 |
ENSG00000120948 | TARDBP | TAR DNA binding protein | [
"Q13148"
] | 1 | 11012344-11030528 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB003703",
"HPA017284"
] | [
"ALS10",
"TDP-43"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor",
"RNA-binding"
] | [
"Amyotrophic lateral sclerosis",
"Disease variant",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 238 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 55: Non-specific - Transcription | Cluster 37: Non-specific - mRNA processing | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,066 | 3 |
ENSG00000120949 | TNFRSF8 | TNF receptor superfamily member 8 | [
"P28908"
] | 1 | 12063303-12144207 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000016",
"HPA014823",
"HPA032081",
"HPA032082"
] | [
"CD30",
"D1S166E",
"KI-1"
] | [
"Cancer-related genes",
"CD markers",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [] | [] | [] | Supported | Approved | null | 6 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 33: Neurons - Mixed function | Cluster 21: Lymphoma - Adaptive immune response | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 7 | Cancer enriched | Detected in some | 10 | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 4 | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 5,067 | 6 |
ENSG00000120952 | PRAMEF2 | PRAME family member 2 | [
"O60811"
] | 1 | 12857086-12861909 | Evidence at transcript level | No human protein/transcript evidence | Evidence at transcript level | Evidence at transcript level | [] | [
"FLJ43580"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 5 | null | null | null | null | Cluster 15: Kidney cancer - Membrane components | null | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,068 | 5 |
ENSG00000120963 | ZNF706 | Zinc finger protein 706 | [
"Q9Y5V0"
] | 8 | 101177878-101206193 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042793"
] | [
"HSPC038"
] | [
"Predicted intracellular proteins"
] | [
"Translation regulation"
] | [
"Repressor"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Approved | null | null | null | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 34: Non-specific - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 5,069 | 5 |
ENSG00000120992 | LYPLA1 | Lysophospholipase 1 | [
"O75608"
] | 8 | 54046367-54102017 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050941",
"HPA063151"
] | [
"APT-1",
"LPL1"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 44: Non-specific - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,070 | 3 |
ENSG00000121005 | CRISPLD1 | Cysteine rich secretory protein LCCL domain containing 1 | [
"Q9H336"
] | 8 | 74984505-75034558 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA024725"
] | [
"Cocoacrisp",
"DKFZp762F133",
"LCRISP1"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted - unknown location"
] | [
"No annotated function"
] | null | Uncertain | null | null | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 5,071 | 6 |
ENSG00000121022 | COPS5 | COP9 signalosome subunit 5 | [
"Q92905"
] | 8 | 67043079-67083783 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004242",
"HPA004845",
"HPA051531"
] | [
"CSN5",
"JAB1",
"MOV-34",
"SGN5"
] | [
"Enzymes",
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 241 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 6 | 0 | 6 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 5,072 | 1 |
ENSG00000121039 | RDH10 | Retinol dehydrogenase 10 | [
"Q8IZV5"
] | 8 | 73294602-73325281 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049199"
] | [
"SDR16C4"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [] | [
"Lipid droplets"
] | [] | [] | [] | Supported | null | null | 6 | null | null | null | Cluster 12: Non-specific - Vasculature | Cluster 72: Neuronal - Signal transduction | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,073 | 1 |
ENSG00000121053 | EPX | Eosinophil peroxidase | [
"P11678"
] | 17 | 58192726-58205174 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA076792"
] | [
"EPO",
"EPP",
"EPX-PEN"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Hydrogen peroxide"
] | [
"Oxidoreductase",
"Peroxidase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 37: Neurons - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in some | 17 | Group enriched | Detected in some | 25 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 23 | 0 | 0 | 0 | [] | [] | [] | 5,074 | 5 |
ENSG00000121057 | AKAP1 | A-kinase anchoring protein 1 | [
"Q92667"
] | 17 | 57085092-57121346 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008620",
"HPA008691",
"CAB019286"
] | [
"AKAP121",
"AKAP149",
"AKAP84",
"D-AKAP1",
"PPP1R43",
"PRKA1",
"S-AKAP84",
"SAKAP84",
"TDRD17"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Supported | null | 76 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 27: Breast cancer - Unknown function | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in many | null | 3 | 2 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 5,075 | 4 |
ENSG00000121058 | COIL | Coilin | [
"P38432"
] | 17 | 56938199-56961050 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017524",
"HPA027885",
"HPA068537",
"CAB069400"
] | [
"CLN80",
"p80-coilin"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear bodies"
] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [] | [] | Supported | Enhanced | null | 109 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 31: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | [
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 5,076 | 4 |
ENSG00000121060 | TRIM25 | Tripartite motif containing 25 | [
"Q14258"
] | 17 | 56836387-56914080 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA005909"
] | [
"EFP",
"RNF147",
"ZNF147"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Host-virus interaction",
"Immunity",
"Innate immunity",
"Ubl conjugation pathway"
] | [
"Ligase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nuclear bodies"
] | [] | [] | Approved | Approved | null | 196 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 31: Non-specific - Antiviral immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 5,077 | 4 |
ENSG00000121064 | SCPEP1 | Serine carboxypeptidase 1 | [
"Q9HB40"
] | 17 | 56978129-57006768 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039102",
"HPA057200"
] | [
"RISC"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Carboxypeptidase",
"Hydrolase",
"Protease"
] | [] | [
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | Approved | Enhanced | null | 4 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 3 | 0 | 3 | [
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 5,078 | 1 |
ENSG00000121067 | SPOP | Speckle type BTB/POZ protein | [
"O43791"
] | 17 | 49598884-49678163 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"BTBD32",
"TEF2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [] | [
"Cancer-related genes",
"Intellectual disability"
] | [] | [] | [] | [] | null | null | null | 126 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 31: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,079 | 6 |
ENSG00000121073 | SLC35B1 | Solute carrier family 35 member B1 | [
"P78383"
] | 17 | 49700934-49709014 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA048655",
"HPA057418"
] | [
"AXER",
"UGTREL1"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Transport"
] | [] | [] | [
"Endoplasmic reticulum"
] | [
"Vesicles"
] | [] | [] | Supported | Approved | null | 21 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 27: Breast cancer - Unknown function | Cluster 8: Non-specific - Secretory pathway | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,081 | 6 |
ENSG00000121075 | TBX4 | T-box transcription factor 4 | [
"P57082"
] | 17 | 61452404-61485110 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB032413",
"HPA044457"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Disease variant"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 64: Connective tissue cells - ECM organization | Cluster 110: Mural cells - ECM organization | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in single | 5 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 5,082 | 8 |
ENSG00000121101 | TEX14 | Testis expressed 14, intercellular bridge forming factor | [
"Q8IWB6"
] | 17 | 58556678-58692055 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030620",
"HPA077020"
] | [
"CT113"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Cytosol"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [] | Approved | Enhanced | null | 5 | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 20: Non-specific - Transcription regulation | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 15 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,083 | 6 |
ENSG00000121104 | FAM117A | Family with sequence similarity 117 member A | [
"Q9C073"
] | 17 | 49710332-49789180 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022531"
] | [] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 12 | null | null | Cluster 32: Basophils - Transcription | Cluster 23: Choroid plexus - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 20: Non-specific - Transcription regulation | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,084 | 8 |
ENSG00000121152 | NCAPH | Non-SMC condensin I complex subunit H | [
"Q15003"
] | 2 | 96335766-96377091 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002647",
"HPA003008"
] | [
"BRRN1",
"CAP-H",
"hCAP-H"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA condensation",
"Mitosis"
] | [] | [
"Disease variant",
"Primary microcephaly"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Supported | Enhanced | null | 165 | Yes | Yes | Cluster 5: Non-specific - Cell proliferation | Cluster 9: Non-specific - Receptor signaling | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 6 | 2 | 5 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,085 | 3 |
ENSG00000121207 | LRAT | Lecithin retinol acyltransferase | [
"O95237"
] | 4 | 154626945-154753120 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA070726"
] | [
"LCA14"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism",
"Sensory transduction",
"Vision"
] | [
"Acyltransferase",
"Transferase"
] | [
"Disease variant",
"Leber congenital amaurosis"
] | [
"Endoplasmic reticulum",
"Golgi apparatus"
] | [
"Plasma membrane",
"Basal body"
] | [] | [] | Approved | null | null | 3 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 39: Astrocytes - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Low cancer specificity | Detected in some | null | Cell type enriched | Detected in many | 12 | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 5,086 | 3 |
ENSG00000121210 | TMEM131L | Transmembrane 131 like | [
"A2VDJ0"
] | 4 | 153466346-153636711 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043472",
"HPA048443"
] | [
"DKFZp586H1322",
"KIAA0922"
] | [
"Predicted membrane proteins"
] | [
"Wnt signaling pathway"
] | [] | [] | [
"Vesicles"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 34: Non-specific - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 51: Lymphoid tissue - Adaptive immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,087 | 3 |
ENSG00000121236 | TRIM6 | Tripartite motif containing 6 | [
"Q9C030"
] | 11 | 5596109-5612958 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA060514"
] | [
"RNF89"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 10 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 15: Kidney cancer - Membrane components | Cluster 22: Non-specific - Basic cellular functions | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in single | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,089 | 6 |
ENSG00000121270 | ABCC11 | ATP binding cassette subfamily C member 11 | [
"Q96J66"
] | 16 | 48165773-48247568 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"MRP8"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 27: Breast cancer - Unknown function | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 55: Breast - Lactation | Tissue enriched | Detected in some | 13 | Group enriched | Detected in some | 8 | Cancer enriched | Detected in some | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,090 | 3 |
ENSG00000121289 | CEP89 | Centrosomal protein 89 | [
"Q96ST8"
] | 19 | 32875925-32971991 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039382"
] | [
"CCDC123",
"FLJ14640"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [] | [
"Cytosol"
] | [
"Primary cilium",
"Centrosome",
"Basal body"
] | [] | [] | Supported | null | null | 17 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 48: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 5,093 | 5 |
ENSG00000121297 | TSHZ3 | Teashirt zinc finger homeobox 3 | [
"Q63HK5"
] | 19 | 31149979-31349436 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008834",
"HPA071010"
] | [
"KIAA1474",
"TSH3",
"ZNF537"
] | [
"Disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane"
] | [] | [] | Enhanced | Approved | null | 27 | No | No | Cluster 21: Neutrophils - Unknown function | Cluster 53: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | 5,094 | 6 |
ENSG00000121310 | ECHDC2 | Enoyl-CoA hydratase domain containing 2 | [
"Q86YB7"
] | 1 | 52895910-52927212 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026731",
"HPA026768"
] | [
"FLJ10948"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Lyase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 7 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 15: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,095 | 4 |
ENSG00000121314 | TAS2R8 | Taste 2 receptor member 8 | [
"Q9NYW2"
] | 12 | 10806051-10807286 | Evidence at protein level | No human protein/transcript evidence | Evidence at protein level | Evidence at protein level | [] | [
"T2R8",
"TRB5"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [
"Sensory transduction",
"Taste"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | null | null | 2 | null | null | null | null | null | Cluster 109: Neurons - Neuronal signaling | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,096 | 5 |
ENSG00000121316 | PLBD1 | Phospholipase B domain containing 1 | [
"Q6P4A8"
] | 12 | 14503661-14567883 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040303"
] | [
"FLJ22662"
] | [
"Predicted intracellular proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Enhanced | null | 34 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 8: Immune cells - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 15: Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 6 | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 5,097 | 1 |
ENSG00000121318 | TAS2R10 | Taste 2 receptor member 10 | [
"Q9NYW0"
] | 12 | 10825219-10826358 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA070201"
] | [
"T2R10",
"TRB2"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [
"Sensory transduction",
"Taste"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Vesicles",
"Plasma membrane"
] | [
"Actin filaments"
] | [] | [] | Approved | null | null | 4 | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 24: Non-specific - Unknown function | null | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,098 | 9 |
ENSG00000121350 | PYROXD1 | Pyridine nucleotide-disulphide oxidoreductase domain 1 | [
"Q8WU10"
] | 12 | 21437615-21471250 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038319",
"HPA038320"
] | [
"DKFZp762G094",
"FLJ22028"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [
"Disease variant",
"Limb-girdle muscular dystrophy",
"Myofibrillar myopathy"
] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 26: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,100 | 1 |
ENSG00000121351 | IAPP | Islet amyloid polypeptide | [
"P10997"
] | 12 | 21354959-21379980 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000352",
"HPA053194"
] | [
"AMYLIN",
"DAP",
"IAP"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hormone"
] | [] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Hormone"
] | Approved | Enhanced | null | 2 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in some | 54 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 40 | Cell type enriched | Detected in some | 42 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,101 | 5 |
ENSG00000121361 | KCNJ8 | Potassium inwardly rectifying channel subfamily J member 8 | [
"Q15842"
] | 12 | 21764955-21775600 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031066"
] | [
"Kir6.1"
] | [
"Disease related genes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Voltage-gated channel"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Uncertain | null | 3 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 34: Testis cancer - Unknown function | Cluster 110: Mural cells - ECM organization | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 15 | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 5,102 | 2 |
ENSG00000121377 | TAS2R7 | Taste 2 receptor member 7 | [
"Q9NYW3"
] | 12 | 10801532-10802627 | Evidence at protein level | No human protein/transcript evidence | Evidence at protein level | Evidence at protein level | [] | [
"T2R7",
"TRB4"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [
"Sensory transduction",
"Taste"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | null | null | 1 | null | null | null | null | null | Cluster 109: Neurons - Neuronal signaling | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,103 | 9 |
ENSG00000121380 | BCL2L14 | BCL2 like 14 | [
"Q9BZR8"
] | 12 | 12049844-12211084 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040665",
"HPA059846"
] | [
"BCL-G",
"BCLG"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Supported | Enhanced | null | 33 | null | null | Cluster 31: T-cells - T-cell receptor | Cluster 51: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma",
"Rectum Adenocarcinoma"
] | 5,104 | 6 |
ENSG00000121381 | TAS2R9 | Taste 2 receptor member 9 | [
"Q9NYW1"
] | 12 | 10809094-10810168 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"T2R9",
"TRB6"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [
"Sensory transduction",
"Taste"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 53: Neurons - Mixed function | null | Cluster 109: Neurons - Neuronal signaling | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,105 | 5 |
ENSG00000121390 | PSPC1 | Paraspeckle component 1 | [
"Q8WXF1"
] | 13 | 19674752-19783019 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038904"
] | [
"FLJ10955",
"PSP1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Immunity",
"Innate immunity",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Repressor",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Enhanced | Supported | null | 328 | No | No | Cluster 10: Non-specific - Membrane trafficking | Cluster 34: Non-specific - Mixed function | Cluster 19: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,106 | 2 |
ENSG00000121410 | A1BG | Alpha-1-B glycoprotein | [
"P04217"
] | 19 | 58345178-58353492 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016673",
"HPA044252"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | Supported | null | 4 | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 18: Liver cancer - Metabolism | Cluster 80: Oligodendrocytes - Myelination | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in single | 736 | Not detected | Not detected | null | Cancer enriched | Detected in single | 962 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 5,108 | 8 |
ENSG00000121413 | ZSCAN18 | Zinc finger and SCAN domain containing 18 | [
"Q8TBC5"
] | 19 | 58083838-58118427 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024318"
] | [
"FLJ12895",
"ZNF447"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Primary cilium",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Supported | null | 15 | No | No | Cluster 22: Eosinophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 4: Non-specific - Transcription | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 5,109 | 7 |
ENSG00000121417 | ZNF211 | Zinc finger protein 211 | [
"Q13398"
] | 19 | 57630395-57644041 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA011340",
"HPA049967"
] | [
"CH2H2-25",
"ZNF-25"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Mitochondria"
] | [
"Rods & Rings"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 4: Non-specific - Transcription | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 5,110 | 4 |
ENSG00000121440 | PDZRN3 | PDZ domain containing ring finger 3 | [
"Q9UPQ7"
] | 3 | 73382431-73624941 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038822",
"HPA061420"
] | [
"KIAA1095",
"LNX3",
"SEMACAP3",
"SEMCAP3"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 9 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 23: Choroid plexus - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 19 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 5,111 | 6 |
ENSG00000121454 | LHX4 | LIM homeobox 4 | [
"Q969G2"
] | 1 | 180230264-180278984 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA055705"
] | [
"Gsh4"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Disease variant",
"Dwarfism",
"Proto-oncogene"
] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | null | null | 57 | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 7 | Low cancer specificity | Detected in many | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,113 | 4 |
ENSG00000121486 | TRMT1L | TRNA methyltransferase 1 like | [
"Q7Z2T5"
] | 1 | 185118101-185157072 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026728",
"HPA054464"
] | [
"C1orf25"
] | [
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Methyltransferase",
"RNA-binding",
"Transferase",
"tRNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 46 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 5,115 | 1 |
ENSG00000121542 | SEC22A | SEC22 homolog A, vesicle trafficking protein | [
"Q96IW7"
] | 3 | 123201927-123274136 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039127"
] | [
"SEC22L2"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [] | [] | Approved | null | null | 94 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 31: Non-specific - Transcription | Cluster 63: Non-specific - Protein processing | Cluster 7: Non-specific - Transcription | Cluster 57: Testis - Spermatogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,116 | 4 |
ENSG00000121552 | CSTA | Cystatin A | [
"P01040"
] | 3 | 122325248-122341969 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000469",
"HPA001031",
"CAB047315"
] | [
"STF1",
"STFA"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell adhesion"
] | [
"Protease inhibitor",
"Thiol protease inhibitor"
] | [
"Cancer-related genes",
"Ichthyosis"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 24 | No | No | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 16 | Group enriched | Detected in many | 19 | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma"
] | 5,117 | 4 |
ENSG00000121570 | DPPA4 | Developmental pluripotency associated 4 | [
"Q7L190"
] | 3 | 109326144-109337546 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020678",
"HPA035249",
"HPA035250"
] | [
"FLJ10713"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein"
] | [] | [
"Nucleoli",
"Nucleoli rim"
] | [
"Nucleoplasm",
"Mitotic chromosome",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 33 | Yes | null | Cluster 8: Plasmacytoid DCs - Unknown function | null | Cluster 34: Testis cancer - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 15 | Cancer enriched | Detected in single | 266 | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 12 | 0 | 0 | 0 | [] | [] | [] | 5,118 | 3 |
ENSG00000121577 | POPDC2 | Popeye domain containing 2 | [
"Q9HBU9"
] | 3 | 119636457-119665324 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA024255"
] | [
"POP2"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 6: Non-specific - Immune response | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 35: Non-specific - Mixed function | Tissue enriched | Detected in many | 4 | Group enriched | Detected in some | 5 | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 5 | Low immune cell specificity | Detected in single | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,119 | 9 |
ENSG00000121578 | B4GALT4 | Beta-1,4-galactosyltransferase 4 | [
"O60513"
] | 3 | 119211732-119240946 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046819",
"HPA063546"
] | [
"beta4Gal-T4"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Golgi apparatus"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Approved | null | 16 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 23: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 5,120 | 4 |
ENSG00000121579 | NAA50 | N-alpha-acetyltransferase 50, NatE catalytic subunit | [
"Q9GZZ1"
] | 3 | 113716458-113746300 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA074489"
] | [
"FLJ13194",
"MAK3",
"NAT13",
"NAT5",
"San"
] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Nucleoli"
] | [] | [] | [] | Supported | Approved | null | 12 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,121 | 1 |
ENSG00000121594 | CD80 | CD80 molecule | [
"P33681"
] | 3 | 119524293-119559614 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025368",
"HPA050092"
] | [
"B7-1",
"B7.1",
"CD28LG",
"CD28LG1"
] | [
"CD markers",
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [
"FDA approved drug targets"
] | [] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | null | Enhanced | null | 6 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 8: Immune cells - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 5 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 5,122 | 6 |
ENSG00000121621 | KIF18A | Kinesin family member 18A | [
"Q8NI77"
] | 11 | 28020619-28108156 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039312",
"HPA039484"
] | [
"DKFZP434G2226",
"PPP1R99"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"Motor protein"
] | [] | [
"Microtubules",
"Cytokinetic bridge"
] | [] | [] | [] | Supported | Approved | null | 20 | Yes | Yes | Cluster 5: Non-specific - Cell proliferation | null | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Group enriched | Detected in some | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 4 | 6 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,123 | 7 |
ENSG00000121634 | GJA8 | Gap junction protein alpha 8 | [
"P48165"
] | 1 | 147902795-147909269 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014715",
"HPA062940"
] | [
"CAE",
"CAE1",
"CX50",
"CZP1"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Cataract",
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 108 | null | null | null | null | Cluster 15: Kidney cancer - Membrane components | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 52 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,124 | 6 |
ENSG00000121644 | DESI2 | Desumoylating isopeptidase 2 | [
"Q9BSY9"
] | 1 | 244653103-244709033 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049950"
] | [
"C1orf121",
"CGI-146",
"DESI-2",
"FAM152A",
"FLJ21998",
"PNAS-4",
"PPPDE1"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | null | null | 10 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 54: Immune cells - T cell receptor | Cluster 45: Non-specific - Nuclear processes | Cluster 81: Alveolar cells - Lung function | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 5,125 | 3 |
ENSG00000121653 | MAPK8IP1 | Mitogen-activated protein kinase 8 interacting protein 1 | [
"Q9UQF2"
] | 11 | 45885651-45906465 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058921",
"HPA070332",
"HPA079657"
] | [
"IB1",
"JIP-1",
"JIP1",
"PRKM8IP"
] | [
"Cancer-related genes",
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes",
"Diabetes mellitus",
"Disease variant"
] | [
"Plasma membrane"
] | [] | [] | [] | Enhanced | Approved | null | 32 | null | null | null | Cluster 20: Macrophages & Microglia - Immune response | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Group enriched | Detected in all | 5 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,126 | 7 |
ENSG00000121680 | PEX16 | Peroxisomal biogenesis factor 16 | [
"Q9Y5Y5"
] | 11 | 45909663-45918812 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043286"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Peroxisome biogenesis"
] | [] | [
"Disease variant",
"Peroxisome biogenesis disorder",
"Zellweger syndrome"
] | [] | [] | [] | [] | null | Approved | null | 28 | null | null | Cluster 6: T-cells - T-cell receptor | Cluster 27: Non-specific - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 5,128 | 1 |
ENSG00000121691 | CAT | Catalase | [
"P04040"
] | 11 | 34438934-34472060 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001515",
"HPA051282",
"HPA055838"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Hydrogen peroxide"
] | [
"Mitogen",
"Oxidoreductase",
"Peroxidase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Vesicles"
] | [] | [] | [] | Enhanced | Enhanced | null | 21 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 50: Non-specific - Nucleic acid binding | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in all | 13 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,130 | 3 |
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