ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000122729 | ACO1 | Aconitase 1 | [
"P21399"
] | 9 | 32384603-32454769 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019371",
"HPA024157"
] | [
"IREB1",
"IREBP",
"IRP1"
] | [
"Cancer-related genes",
"Citric acid cycle related proteins",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Tricarboxylic acid cycle"
] | [
"Lyase",
"RNA-binding"
] | [
"Cancer-related genes"
] | [
"Mitochondria",
"Cytosol"
] | [] | [] | [] | Supported | Enhanced | null | 6 | null | null | Cluster 41: Basophils - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 89: Adipocytes - Lipid metabolism | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,245 | 4 |
ENSG00000122741 | DCAF10 | DDB1 and CUL4 associated factor 10 | [
"Q5QP82"
] | 9 | 37800554-37867666 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA024160"
] | [
"FLJ23201",
"MGC10765",
"WDR32"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoli fibrillar center"
] | [] | [] | [] | Approved | Uncertain | null | 31 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 31: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,248 | 5 |
ENSG00000122756 | CNTFR | Ciliary neurotrophic factor receptor | [
"P26992"
] | 9 | 34551432-34590140 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025310"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Receptor"
] | [] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 108: Fibroblasts - ECM organization | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 12 | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 5,249 | 9 |
ENSG00000122778 | KIAA1549 | KIAA1549 | [
"Q9HCM3"
] | 7 | 138831381-138981389 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019560"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [] | [
"Retinitis pigmentosa"
] | [
"Nuclear membrane"
] | [
"Intermediate filaments"
] | [] | [] | Approved | Uncertain | null | 4 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,250 | 6 |
ENSG00000122779 | TRIM24 | Tripartite motif containing 24 | [
"O15164"
] | 7 | 138460259-138589996 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043495",
"HPA061717"
] | [
"hTIF1",
"RNF82",
"TIF1",
"Tif1a"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"DNA-binding",
"Repressor",
"Transferase"
] | [
"Cancer-related genes",
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 69 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 49: HMC-1 - Innate immune response | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,251 | 6 |
ENSG00000122783 | CYREN | Cell cycle regulator of NHEJ | [
"Q9BWK5"
] | 7 | 135092363-135170795 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA020060"
] | [
"C7orf49",
"FLJ22450",
"FLJ27285",
"MGC5242",
"MRI",
"MRI-2"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 3 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 30: White matter - Myelination | Cluster 39: Non-specific - Transcription | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 5,252 | 4 |
ENSG00000122786 | CALD1 | Caldesmon 1 | [
"Q05682"
] | 7 | 134744252-134970729 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000006",
"HPA008066",
"HPA017330"
] | [
"CDM",
"H-CAD",
"h-CD",
"L-CAD"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Calmodulin-binding",
"Muscle protein"
] | [] | [
"Plasma membrane",
"Actin filaments"
] | [] | [] | [] | Enhanced | Enhanced | null | 108 | Yes | No | Cluster 4: Neutrophils - Degranulation | Cluster 42: Choroid plexus - Mitochondria | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 8 | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 5,253 | 5 |
ENSG00000122824 | NUDT10 | Nudix hydrolase 10 | [
"Q8NFP7"
] | X | 51332231-51337525 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047027",
"HPA057684"
] | [
"DIPP3a",
"hDIPP3alpha"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 8 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 12: Bone cancer - Neuronal signaling | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 65: Brain - Transcription | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 6 | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,255 | 3 |
ENSG00000122852 | SFTPA1 | Surfactant protein A1 | [
"Q8IWL2"
] | 10 | 79610939-79615455 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016793",
"HPA042638",
"HPA045752",
"HPA049368"
] | [
"COLEC4",
"SFTP1",
"SP-A",
"SP-A1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [
"Gaseous exchange"
] | [] | [
"Disease variant"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Other"
] | null | Supported | null | 3 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 37: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 81: Alveolar cells - Lung function | Cluster 13: Lung - Secretion | Tissue enriched | Detected in some | 1,048 | Cancer enriched | Detected in single | 7 | Group enriched | Detected in some | 27 | Cell type enriched | Detected in some | 7 | Immune cell enriched | Detected in single | 27 | 0 | 0 | 0 | [] | [] | [] | 5,256 | 1 |
ENSG00000122859 | NEUROG3 | Neurogenin 3 | [
"Q9Y4Z2"
] | 10 | 69571698-69573422 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039785"
] | [
"Atoh5",
"bHLHa7",
"Math4B",
"ngn3"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Disease variant"
] | [
"Nuclear speckles"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 54 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 7: Small intestine - Absorption and Digestion | Group enriched | Detected in some | 13 | Cancer enriched | Detected in some | 5 | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in single | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,257 | 2 |
ENSG00000122861 | PLAU | Plasminogen activator, urokinase | [
"P00749"
] | 10 | 73909177-73917496 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA070796"
] | [
"UPA",
"URK"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Blood coagulation",
"Fibrinolysis",
"Hemostasis",
"Plasminogen activation"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Cancer-related genes"
] | [
"Golgi apparatus",
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Blood coagulation"
] | Approved | Supported | null | 13 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 12: Non-specific - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 5 | Group enriched | Detected in some | 9 | 3 | 0 | 3 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,258 | 8 |
ENSG00000122862 | SRGN | Serglycin | [
"P10124"
] | 10 | 69088103-69104805 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000759"
] | [
"PPG",
"PRG",
"PRG1"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Apoptosis",
"Biomineralization"
] | [] | [] | [
"Golgi apparatus"
] | [] | [
"Secreted to blood"
] | [
"Other"
] | Supported | Enhanced | null | 8 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 15: Bone marrow - Innate immune response | Tissue enriched | Detected in all | 10 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 5,259 | 9 |
ENSG00000122863 | CHST3 | Carbohydrate sulfotransferase 3 | [
"Q7LGC8"
] | 10 | 71964395-72013558 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047523",
"HPA055704"
] | [
"C6ST",
"C6ST1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Carbohydrate metabolism"
] | [
"Transferase"
] | [
"Disease variant"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 1 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 15: Kidney cancer - Membrane components | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,260 | 4 |
ENSG00000122870 | BICC1 | BicC family RNA binding protein 1 | [
"Q9H694"
] | 10 | 58512872-58831435 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA070797"
] | [] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein",
"RNA-binding"
] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Centrosome"
] | [] | [] | Approved | null | null | null | null | null | Cluster 41: Basophils - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 10 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 5,261 | 9 |
ENSG00000122873 | CISD1 | CDGSH iron sulfur domain 1 | [
"Q9NZ45"
] | 10 | 58269162-58289586 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA074383"
] | [
"C10orf70",
"MDS029",
"mitoNEET",
"ZCD1"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [] | [
"Transferase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Supported | null | 8 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 23: Choroid plexus - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 5,262 | 2 |
ENSG00000122877 | EGR2 | Early growth response 2 | [
"P11161"
] | 10 | 62811996-62819167 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031165",
"HPA065377"
] | [
"KROX20"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"Activator",
"DNA-binding",
"Transferase"
] | [
"Charcot-Marie-Tooth disease",
"Dejerine-Sottas syndrome",
"Disease variant",
"Neurodegeneration",
"Neuropathy"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 3 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 29: Forebrain - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 22: Epididymis - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 2 | 0 | 2 | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,263 | 2 |
ENSG00000122882 | ECD | Ecdysoneless cell cycle regulator | [
"O95905"
] | 10 | 73130155-73169055 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006465"
] | [
"GCR2",
"hSGT1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing",
"Transcription",
"Transcription regulation"
] | [
"Activator"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 55 | Yes | No | Cluster 28: Neutrophils - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Chromophobe"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe"
] | 5,264 | 2 |
ENSG00000122884 | P4HA1 | Prolyl 4-hydroxylase subunit alpha 1 | [
"P13674"
] | 10 | 73007217-73096974 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007599",
"HPA026593"
] | [
"C-P4Halpha(I)",
"P4HA"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Endoplasmic reticulum"
] | [
"Vesicles",
"Mitochondria"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Enhanced | null | 51 | Yes | No | Cluster 40: Monocytes - Innate immune response | Cluster 55: Non-specific - Transcription | Cluster 15: Kidney cancer - Membrane components | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 7 | 0 | 7 | [] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Glioblastoma Multiforme",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,265 | 9 |
ENSG00000122912 | SLC25A16 | Solute carrier family 25 member 16 | [
"P16260"
] | 10 | 68477998-68527523 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA036243",
"HPA044580"
] | [
"D10S105E",
"GDA",
"HGT.1",
"ML7"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 89: Adipocytes - Lipid metabolism | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 5,266 | 9 |
ENSG00000122952 | ZWINT | ZW10 interacting kinetochore protein | [
"O95229"
] | 10 | 56357227-56361273 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005757",
"HPA022264"
] | [
"KNTC2AP",
"SIP30",
"Zwint1"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Cytosol"
] | [] | [] | Enhanced | null | null | 58 | No | Yes | Cluster 12: Non-specific - Mitochondrial translation | Cluster 38: Sub-cortical - Mixed function | Cluster 52: Non-specific - Mitochondria | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 4 | 4 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 5,267 | 1 |
ENSG00000122958 | VPS26A | VPS26 retromer complex component A | [
"O75436"
] | 10 | 69123512-69174412 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011602",
"HPA057498",
"CAB075733"
] | [
"Hbeta58",
"PEP8A",
"VPS26"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Endosomes",
"Lysosomes"
] | [] | [] | [] | Enhanced | Supported | null | 44 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 52: Non-specific - Mitochondria | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,268 | 6 |
ENSG00000122965 | RBM19 | RNA binding motif protein 19 | [
"Q9Y4C8"
] | 12 | 113816738-113966325 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038860",
"HPA058732"
] | [
"DKFZp586F1023",
"KIAA0682",
"Mrd1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein",
"RNA-binding"
] | [] | [
"Nucleoli"
] | [] | [] | [] | Supported | Supported | null | 50 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 38: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 5,269 | 1 |
ENSG00000122966 | CIT | Citron rho-interacting serine/threonine kinase | [
"O14578"
] | 12 | 119685791-119877320 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019082",
"HPA048812",
"HPA075506"
] | [
"CITK",
"CRIK",
"KIAA0949",
"STK21"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Differentiation",
"Mitosis",
"Neurogenesis"
] | [
"Developmental protein",
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Disease variant",
"Primary microcephaly"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 18 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,270 | 1 |
ENSG00000122970 | IFT81 | Intraflagellar transport 81 | [
"Q8WYA0"
] | 12 | 110124335-110218793 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019087",
"HPA020051"
] | [
"CDV-1R",
"CDV1",
"MGC4027"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [
"Cilium biogenesis/degradation",
"Differentiation",
"Spermatogenesis"
] | [] | [
"Ciliopathy",
"Disease variant"
] | [
"Cytosol"
] | [
"Primary cilium",
"Centrosome",
"Basal body"
] | [] | [] | Approved | Enhanced | null | 45 | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 21: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 5,271 | 8 |
ENSG00000122971 | ACADS | Acyl-CoA dehydrogenase short chain | [
"P16219"
] | 12 | 120725774-120740008 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004799",
"CAB019284",
"HPA022271"
] | [
"ACAD3",
"SCAD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Centrosome",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Supported | Enhanced | null | 1 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 19: Astrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 5,272 | 2 |
ENSG00000122986 | HVCN1 | Hydrogen voltage gated channel 1 | [
"Q96D96"
] | 12 | 110627841-110704950 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039329"
] | [
"Hv1",
"MGC15619",
"VSOP"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Fertilization",
"Hydrogen ion transport",
"Immunity",
"Innate immunity",
"Ion transport",
"Transport"
] | [
"Ion channel",
"Voltage-gated channel"
] | [] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | Cluster 22: Eosinophils - Transcription | Cluster 42: Choroid plexus - Mitochondria | Cluster 55: Lymphoma - Immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enriched | Detected in all | 7 | Group enriched | Detected in many | 14 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 5,273 | 7 |
ENSG00000123064 | DDX54 | DEAD-box helicase 54 | [
"Q8TDD1"
] | 12 | 113157173-113185479 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028244",
"HPA070786"
] | [
"APR-5",
"DP97",
"MGC2835"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Nucleoplasm",
"Nucleoli",
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 38 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 36: Choroid plexus - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 5,274 | 1 |
ENSG00000123066 | MED13L | Mediator complex subunit 13L | [
"Q71F56"
] | 12 | 115957905-116277693 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA039445"
] | [
"KIAA1025",
"THRAP2",
"TRAP240L"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Repressor"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Uncertain | null | 74 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 15: Non-specific - Transcription | Cluster 38: Non-specific - Transcription | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,275 | 3 |
ENSG00000123080 | CDKN2C | Cyclin dependent kinase inhibitor 2C | [
"P42773"
] | 1 | 50960745-50974634 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB005303",
"CAB018398",
"HPA019057",
"HPA019764"
] | [
"INK4C",
"p18"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 34 | null | Yes | Cluster 3: Non-specific - Nuclear processes | Cluster 11: White matter - Signal transduction | Cluster 10: Ciliated cells - Ion channel activity | Cluster 27: Non-specific - Cell proliferation | Cluster 61: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 5,276 | 5 |
ENSG00000123091 | RNF11 | Ring finger protein 11 | [
"Q9Y3C5"
] | 1 | 51236273-51273447 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045781"
] | [
"CGI-123",
"MGC51169",
"Sid1669p"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 200 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 37: Non-specific - mRNA processing | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,277 | 7 |
ENSG00000123095 | BHLHE41 | Basic helix-loop-helix family member e41 | [
"Q9C0J9"
] | 12 | 26120030-26125037 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056035",
"HPA077617"
] | [
"BHLHB3",
"DEC2",
"SHARP-1",
"SHARP1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | null | null | 3 | null | null | Cluster 17: B-cells - Immunoglobulins | Cluster 30: White matter - Myelination | Cluster 15: Kidney cancer - Membrane components | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 5,279 | 7 |
ENSG00000123096 | SSPN | Sarcospan | [
"Q14714"
] | 12 | 26121991-26299290 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA066432"
] | [
"KRAG",
"SPN1",
"SPN2"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nuclear membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | null | null | null | No | No | Cluster 17: B-cells - Immunoglobulins | Cluster 39: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 12 | 3 | 2 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Bladder Urothelial Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 5,280 | 1 |
ENSG00000123104 | ITPR2 | Inositol 1,4,5-trisphosphate receptor type 2 | [
"Q14571"
] | 12 | 26335352-26833194 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA059144",
"HPA062260"
] | [
"CFAP48",
"IP3R2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"Disease variant"
] | [
"Endoplasmic reticulum",
"Mid piece"
] | [
"Nucleoplasm",
"Principal piece",
"End piece"
] | [] | [] | Approved | Uncertain | null | 10 | null | null | Cluster 41: Basophils - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,281 | 5 |
ENSG00000123106 | CCDC91 | Coiled-coil domain containing 91 | [
"Q7Z6B0"
] | 12 | 28133249-28581511 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038169"
] | [
"DKFZp779L1558",
"FLJ11088",
"p56"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Golgi apparatus",
"Acrosome"
] | [
"Equatorial segment",
"Flagellar centriole"
] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 32: Basophils - Transcription | Cluster 37: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 4 | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Rectum Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 5,282 | 2 |
ENSG00000123119 | NECAB1 | N-terminal EF-hand calcium binding protein 1 | [
"Q8N987"
] | 8 | 90791741-90959393 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023252",
"HPA023629",
"HPA025963",
"HPA031262",
"CAB068208",
"CAB068209",
"CAB068210"
] | [
"EFCBP1"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Mitotic spindle",
"Primary cilium",
"Primary cilium tip",
"Cytosol"
] | [] | [] | Supported | Enhanced | Supported | 11 | Yes | null | null | Cluster 53: Neurons - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 5,283 | 8 |
ENSG00000123124 | WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | [
"Q9H0M0"
] | 8 | 86342547-86478420 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023180"
] | [
"AIP5",
"DKFZP434D2111"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Host-virus interaction",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Cytosol"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 64 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 40: Non-specific - Unknown function | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,284 | 3 |
ENSG00000123130 | ACOT9 | Acyl-CoA thioesterase 9 | [
"Q9Y305"
] | X | 23701055-23766475 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035533"
] | [
"ACATE2",
"CGI-16",
"MT-ACT48"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Hydrolase",
"Serine esterase"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Supported | null | 8 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 23: Choroid plexus - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,285 | 8 |
ENSG00000123131 | PRDX4 | Peroxiredoxin 4 | [
"Q13162"
] | X | 23664262-23686397 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB008659",
"CAB027389",
"CAB047362",
"HPA067039",
"CAB080373",
"CAB080374"
] | [
"AOE37-2"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Antioxidant",
"Oxidoreductase",
"Peroxidase"
] | [
"Cancer-related genes"
] | [
"Endoplasmic reticulum"
] | [
"Cytosol"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Enhanced | null | 31 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 6 | 0 | 6 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,286 | 9 |
ENSG00000123144 | TRIR | Telomerase RNA component interacting RNase | [
"Q9BQ61"
] | 19 | 12730640-12734684 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA059965"
] | [
"C19orf43",
"fSAP18",
"MGC2803",
"TERCIR"
] | [
"Predicted intracellular proteins"
] | [] | [
"Exonuclease",
"Hydrolase",
"Nuclease",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 7 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 15: Non-specific - Protein processing | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 5,289 | 2 |
ENSG00000123146 | ADGRE5 | Adhesion G protein-coupled receptor E5 | [
"P48960"
] | 19 | 14380501-14408725 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013707"
] | [
"CD97",
"TM7LN1"
] | [
"CD markers",
"G-protein coupled receptors",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Cell adhesion"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Plasma membrane"
] | [
"Golgi apparatus"
] | [
"Secreted to blood"
] | [
"Receptor"
] | Approved | Enhanced | null | 4 | null | Yes | Cluster 7: Non-specific - Innate immune response | Cluster 11: White matter - Signal transduction | Cluster 23: Non-specific - Transcription | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Rectum Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 5,290 | 4 |
ENSG00000123154 | WDR83 | WD repeat domain 83 | [
"Q9BRX9"
] | 19 | 12666802-12675832 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042629",
"HPA042838"
] | [
"MORG1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm",
"Vesicles"
] | [
"Centriolar satellite",
"Basal body",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 90 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 13: Oligodendrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,291 | 1 |
ENSG00000123159 | GIPC1 | GIPC PDZ domain containing family member 1 | [
"O14908"
] | 19 | 14477760-14496149 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043958",
"HPA061786"
] | [
"C19orf3",
"GIPC",
"GLUT1CBP",
"Hs.6454",
"NIP",
"RGS19IP1",
"SEMCAP",
"SYNECTIN",
"TIP-2"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Congenital muscular dystrophy",
"Dystroglycanopathy"
] | [
"Plasma membrane",
"Cell Junctions"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 50 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 18: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 5,292 | 8 |
ENSG00000123165 | ACTRT1 | Actin related protein T1 | [
"Q8TDG2"
] | X | 128050962-128052403 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA003119"
] | [
"AIP1",
"ARIP1",
"Arp-T1",
"KIAA0705"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [] | [] | [] | [] | null | Supported | null | 8 | null | null | null | null | null | null | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in single | 40 | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,293 | 4 |
ENSG00000123171 | CCDC70 | Coiled-coil domain containing 70 | [
"Q6NSX1"
] | 13 | 51861969-51866232 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA079644"
] | [
"DKFZP434K1172",
"FLJ25853"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 13 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in single | 1,186 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,294 | 8 |
ENSG00000123178 | SPRYD7 | SPRY domain containing 7 | [
"Q5W111"
] | 13 | 49912702-49936490 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043934"
] | [
"C13orf1",
"CLLD6"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 15 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 19: Non-specific - Unknown function | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,295 | 9 |
ENSG00000123179 | EBPL | EBP like | [
"Q9BY08"
] | 13 | 49660674-49691486 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049891"
] | [
"EBRP"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Enhanced | null | null | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 21: Non-specific - Metabolism | Cluster 19: Non-specific - Unknown function | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,296 | 1 |
ENSG00000123191 | ATP7B | ATPase copper transporting beta | [
"P35670"
] | 13 | 51930436-52012125 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009137",
"HPA013187"
] | [
"WND"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Copper transport",
"Ion transport",
"Transport"
] | [
"Translocase"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Supported | null | 10 | null | null | null | Cluster 29: Forebrain - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,297 | 9 |
ENSG00000123200 | ZC3H13 | Zinc finger CCCH-type containing 13 | [
"Q5T200"
] | 13 | 45954465-46052759 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039340",
"HPA040140",
"HPA047806"
] | [
"DKFZp434D1812",
"KIAA0853",
"Xio"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Developmental protein"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Uncertain | null | 15 | null | null | Cluster 41: Basophils - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,298 | 1 |
ENSG00000123213 | NLN | Neurolysin | [
"Q9BYT8"
] | 5 | 65722205-65871725 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA031862"
] | [
"AGTBP",
"KIAA1226"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | null | Yes | No | Cluster 40: Monocytes - Innate immune response | Cluster 14: Neurons - Synaptic function | Cluster 7: Liver cancer - Metabolism | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Group enriched | Detected in some | 5 | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 5,299 | 2 |
ENSG00000123219 | CENPK | Centromere protein K | [
"Q9BS16"
] | 5 | 65517766-65563168 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CENP-K",
"FKSG14",
"SOLT"
] | [
"Disease related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 22 | null | Yes | Cluster 5: Non-specific - Cell proliferation | Cluster 6: Non-specific - Immune response | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 5 | 4 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,300 | 7 |
ENSG00000123243 | ITIH5 | Inter-alpha-trypsin inhibitor heavy chain 5 | [] | 10 | 7559270-7666998 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA038305"
] | [
"MGC10848"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [
"Secreted to blood"
] | [] | Approved | Approved | null | null | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 69: Skin cancer - ECM organization | Cluster 22: Non-specific - Basic cellular functions | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,302 | 4 |
ENSG00000123268 | ATF1 | Activating transcription factor 1 | [
"P18846"
] | 12 | 50763710-50821162 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB016222",
"HPA055069",
"HPA055406"
] | [
"TREB36"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 9 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 35: Non-specific - DNA binding | Cluster 38: Non-specific - Transcription | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,303 | 7 |
ENSG00000123297 | TSFM | Ts translation elongation factor, mitochondrial | [
"P43897"
] | 12 | 57782761-57808071 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006204"
] | [
"EF-TS",
"EF-Tsmt"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Elongation factor"
] | [
"Cardiomyopathy",
"Disease variant",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Supported | null | null | 38 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 23: Choroid plexus - Mixed function | Cluster 38: Non-specific - Transcription | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 5,304 | 2 |
ENSG00000123307 | NEUROD4 | Neuronal differentiation 4 | [
"Q9HD90"
] | 12 | 55019974-55030017 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015545",
"HPA026998",
"HPA055750"
] | [
"ATH-3",
"Atoh3",
"bHLHa4",
"MATH-3"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Centrosome",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 2 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 42: Retina - Visual perception | Group enriched | Detected in some | 11 | Group enriched | Detected in some | 4 | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 5,305 | 2 |
ENSG00000123329 | ARHGAP9 | Rho GTPase activating protein 9 | [
"Q9BRR9"
] | 12 | 57472264-57488814 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA078822"
] | [
"10C",
"MGC1295"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Plasma membrane"
] | [
"Cell Junctions"
] | [] | [] | Approved | null | null | 14 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | 5,306 | 7 |
ENSG00000123338 | NCKAP1L | NCK associated protein 1 like | [
"P55160"
] | 12 | 54497752-54548243 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039490",
"HPA040772"
] | [
"HEM1"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Approved | null | null | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 20: Macrophages & Microglia - Immune response | Cluster 12: Bone cancer - Neuronal signaling | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 5,307 | 7 |
ENSG00000123342 | MMP19 | Matrix metallopeptidase 19 | [
"Q99542"
] | 12 | 55835433-55842966 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA070804"
] | [
"MMP18",
"RASI-1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted secreted proteins"
] | [
"Angiogenesis",
"Collagen degradation",
"Differentiation"
] | [
"Developmental protein",
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Endoplasmic reticulum",
"Vesicles"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | Approved | null | null | null | null | null | null | Cluster 12: Non-specific - Vasculature | Cluster 34: Testis cancer - Unknown function | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,308 | 2 |
ENSG00000123349 | PFDN5 | Prefoldin subunit 5 | [
"Q99471"
] | 12 | 53295291-53299452 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008587"
] | [
"MM-1",
"PFD5"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Intermediate filaments",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 134 | null | null | Cluster 18: Non-specific - Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 5,309 | 1 |
ENSG00000123352 | SPATS2 | Spermatogenesis associated serine rich 2 | [
"Q86XZ4"
] | 12 | 49366584-49527425 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038642",
"HPA038643",
"HPA076823"
] | [
"FLJ13117",
"SCR59",
"SPATA10"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Enhanced | Uncertain | null | 27 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 5,310 | 7 |
ENSG00000123353 | ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 | [
"Q53FV1"
] | 12 | 55818041-55821879 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065643"
] | [
"adoplin-2",
"HSPC160",
"MST095",
"MSTP095"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | null | null | 20 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,311 | 2 |
ENSG00000123358 | NR4A1 | Nuclear receptor subfamily 4 group A member 1 | [
"P22736"
] | 12 | 52022832-52059507 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027311",
"HPA059742",
"HPA070142"
] | [
"GFRP1",
"HMR",
"N10",
"NAK-1",
"NGFIB",
"NUR77",
"TR3"
] | [
"Nuclear receptors",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Inflammatory response",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Receptor"
] | [] | [
"Nucleoplasm"
] | [
"Nuclear membrane",
"Nucleoli fibrillar center",
"Nuclear speckles",
"Cytosol"
] | [] | [] | Supported | Approved | null | 48 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 15: Non-specific - Transcription | Cluster 7: Liver cancer - Metabolism | Cluster 103: Non-specific - Basic cellular processes | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 12 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | 5,312 | 3 |
ENSG00000123360 | PDE1B | Phosphodiesterase 1B | [
"Q01064"
] | 12 | 54549601-54579239 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018492"
] | [
"PDES1B"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding",
"Hydrolase"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in many | 8 | Group enriched | Detected in some | 8 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,313 | 1 |
ENSG00000123364 | HOXC13 | Homeobox C13 | [
"P31276"
] | 12 | 53938831-53946544 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051634"
] | [
"HOX3",
"HOX3G"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant",
"Ectodermal dysplasia"
] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | null | null | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 26: Keratinocytes - Keratinization | Cluster 9: Skin - Hair follicle development | Tissue enriched | Detected in some | 9 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 5,314 | 3 |
ENSG00000123384 | LRP1 | LDL receptor related protein 1 | [
"Q07954"
] | 12 | 57128483-57213361 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004182",
"CAB018621",
"HPA022903"
] | [
"A2MR",
"APOER",
"APR",
"CD91",
"IGFBP-3R",
"IGFBP3R1",
"LRP",
"LRP1A"
] | [
"Candidate cardiovascular disease genes",
"CD markers",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Endocytosis",
"Host-virus interaction"
] | [
"Developmental protein",
"Receptor"
] | [
"Disease variant"
] | [
"Plasma membrane"
] | [
"Nucleoli",
"Cytosol"
] | [
"Intracellular and membrane"
] | [
"Receptor"
] | Supported | Supported | null | 31 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 44: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 18 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,316 | 8 |
ENSG00000123388 | HOXC11 | Homeobox C11 | [
"O43248"
] | 12 | 53973126-53977643 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038291"
] | [
"HOX3H"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 4 | null | null | null | null | Cluster 65: Non-specific - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 9: Skin - Hair follicle development | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 5,317 | 3 |
ENSG00000123395 | ATG101 | Autophagy related 101 | [
"Q9BSB4"
] | 12 | 52069246-52077495 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039904"
] | [
"C12orf44",
"FLJ11773"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Autophagy"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 39 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 38: Non-specific - Transcription | Cluster 26: Keratinocytes - Keratinization | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in all | 5 | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 5,318 | 5 |
ENSG00000123407 | HOXC12 | Homeobox C12 | [
"P31275"
] | 12 | 53954903-53958956 | Evidence at protein level | Evidence at transcript level | No human protein/transcript evidence | Evidence at protein level | [
"HPA055632"
] | [
"HOC3F",
"HOX3",
"HOX3F"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 65: Non-specific - Unknown function | Cluster 26: Keratinocytes - Keratinization | Cluster 9: Skin - Hair follicle development | Group enriched | Detected in some | 16 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,320 | 7 |
ENSG00000123411 | IKZF4 | IKAROS family zinc finger 4 | [
"Q9H2S9"
] | 12 | 56007659-56038435 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046270",
"HPA049016"
] | [
"Eos",
"ZNFN1A4"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | [] | Supported | Approved | null | 14 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 25: Non-specific - Transcription | Cluster 21: Lymphoma - Adaptive immune response | Cluster 103: Non-specific - Basic cellular processes | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cell type specificity | Detected in many | null | Immune cell enriched | Detected in single | 4 | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 5,321 | 4 |
ENSG00000123415 | SMUG1 | Single-strand-selective monofunctional uracil-DNA glycosylase 1 | [
"Q53HV7"
] | 12 | 54121277-54189008 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026804",
"HPA065892"
] | [
"FDG",
"HMUDG",
"UNG3"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"DNA-binding",
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center",
"Cytosol"
] | [] | [] | Supported | null | null | 9 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 20: Macrophages & Microglia - Immune response | Cluster 38: Non-specific - Transcription | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,322 | 7 |
ENSG00000123416 | TUBA1B | Tubulin alpha 1b | [
"P68363"
] | 12 | 49127782-49131397 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011513",
"HPA039247",
"HPA043684",
"HPA063394"
] | [
"K-ALPHA-1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Microtubules"
] | [
"Primary cilium"
] | [] | [] | Enhanced | Enhanced | null | 134 | null | Yes | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 38: Non-specific - Transcription | Cluster 27: Non-specific - Cell proliferation | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 6 | 2 | [
"Lung Squamous Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Lung Squamous Cell Carcinoma"
] | 5,323 | 3 |
ENSG00000123427 | EEF1AKMT3 | EEF1A lysine methyltransferase 3 | [
"Q96AZ1"
] | 12 | 57771492-57782541 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043020",
"HPA045492"
] | [
"DKFZP586D0919",
"FAM119B",
"METTL21B"
] | [
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Transferase"
] | [] | [
"Centrosome"
] | [
"Nucleoplasm",
"Mitotic chromosome"
] | [] | [] | Approved | Uncertain | null | 176 | Yes | null | Cluster 33: Non-specific - ATP binding | Cluster 6: Non-specific - Immune response | Cluster 38: Non-specific - Transcription | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 5,324 | 3 |
ENSG00000123444 | KBTBD4 | Kelch repeat and BTB domain containing 4 | [
"Q9NVX7"
] | 11 | 47572197-47578976 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037792",
"HPA037793"
] | [
"BKLHD4",
"FLJ10450",
"HSPC252"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 20 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 31: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,325 | 2 |
ENSG00000123453 | SARDH | Sarcosine dehydrogenase | [
"Q9UL12"
] | 9 | 133663560-133739955 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057267",
"HPA058086"
] | [
"DMGDHL1",
"SDH"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 20 | null | null | Cluster 31: T-cells - T-cell receptor | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 59: Leukemia - T-cell receptor | Cluster 93: Hepatocytes - Bile production & excretion | Cluster 45: Liver - Metabolism & Coagulation | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in all | 5 | Group enriched | Detected in many | 5 | Group enriched | Detected in some | 5 | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 5,326 | 5 |
ENSG00000123454 | DBH | Dopamine beta-hydroxylase | [
"P09172"
] | 9 | 133636363-133659329 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002130",
"HPA005960",
"HPA070789"
] | [
"DBM"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Catecholamine biosynthesis"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Vesicles"
] | [
"Endoplasmic reticulum"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Enhanced | null | 18 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enriched | Detected in some | 7 | Cancer enriched | Detected in some | 24 | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 5,327 | 6 |
ENSG00000123472 | ATPAF1 | ATP synthase mitochondrial F1 complex assembly factor 1 | [
"Q5TC12"
] | 1 | 46632737-46673867 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028382",
"HPA044950"
] | [
"ATP11",
"Atp11p",
"FLJ22351"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 16 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 37: Non-specific - mRNA processing | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 5,328 | 4 |
ENSG00000123473 | STIL | STIL centriolar assembly protein | [
"Q15468"
] | 1 | 47250139-47314892 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028388"
] | [
"MCPH7",
"SIL"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Developmental protein"
] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability",
"Primary microcephaly",
"Proto-oncogene"
] | [
"Nucleoplasm",
"Centrosome",
"Basal body"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 30 | null | Yes | Cluster 13: Non-specific - Mitochondria | Cluster 34: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 5,329 | 7 |
ENSG00000123485 | HJURP | Holliday junction recognition protein | [
"Q8NCD3"
] | 2 | 233833416-233854566 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008436",
"HPA027261"
] | [
"DKFZp762E1312",
"FAKTS",
"hFLEG1",
"URLC9"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [
"Chaperone",
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 24 | Yes | Yes | Cluster 9: T-regs - Cell cycle regulation | Cluster 48: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 27: Non-specific - Cell proliferation | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 6 | 4 | 4 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 5,330 | 4 |
ENSG00000123496 | IL13RA2 | Interleukin 13 receptor subunit alpha 2 | [
"Q14627"
] | X | 115003975-115019977 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045831",
"HPA067363"
] | [
"CD213a2",
"CT19",
"IL-13R",
"IL13BP"
] | [
"Cancer-related genes",
"CD markers",
"Predicted membrane proteins"
] | [] | [
"Receptor"
] | [
"Cancer-related genes"
] | [
"Plasma membrane",
"Cell Junctions"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | null | null | 12 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 72: Neuronal - Signal transduction | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,331 | 6 |
ENSG00000123500 | COL10A1 | Collagen type X alpha 1 chain | [
"Q03692"
] | 6 | 116118909-116158747 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA053268"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [] | [] | [
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [
"Secreted to extracellular matrix"
] | [
"No annotated function"
] | Approved | null | null | 17 | null | null | null | Cluster 50: Non-specific - Nucleic acid binding | Cluster 72: Neuronal - Signal transduction | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 55: Breast - Lactation | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 5,332 | 8 |
ENSG00000123505 | AMD1 | Adenosylmethionine decarboxylase 1 | [
"P17707"
] | 6 | 110874770-110898879 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029281",
"HPA029282"
] | [
"SAMDC"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Polyamine biosynthesis",
"Spermidine biosynthesis"
] | [
"Decarboxylase",
"Lyase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 6 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 20: Non-specific - Transcription regulation | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 4 | 1 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,333 | 2 |
ENSG00000123545 | NDUFAF4 | NADH:ubiquinone oxidoreductase complex assembly factor 4 | [
"Q9P032"
] | 6 | 96889315-96897891 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030216",
"HPA046560"
] | [
"bA22L21.1",
"C6orf66",
"HRPAP20",
"HSPC125",
"My013"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [
"Calmodulin-binding"
] | [
"Disease variant",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 52 | null | Yes | Cluster 43: Non-specific - Transcription & Translation | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 28: Non-specific - Nuclear processes | Cluster 17: Non-specific - RNA processing | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,334 | 2 |
ENSG00000123552 | USP45 | Ubiquitin specific peptidase 45 | [
"Q70EL2"
] | 6 | 99432325-99521728 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029602",
"HPA029604",
"HPA075668"
] | [
"MGC14793"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Disease variant",
"Leber congenital amaurosis"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 11 | null | null | Cluster 24: Non-specific - Transcription | Cluster 35: Non-specific - DNA binding | Cluster 28: Non-specific - Nuclear processes | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 5,335 | 4 |
ENSG00000123560 | PLP1 | Proteolipid protein 1 | [
"P60201"
] | X | 103773718-103792619 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA004128"
] | [
"GPM6C",
"PLP",
"SPG2"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Cancer-related genes",
"Disease variant",
"Hereditary spastic paraplegia",
"Leukodystrophy",
"Neurodegeneration"
] | [] | [] | [] | [] | null | Enhanced | null | 8 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 30: White matter - Myelination | Cluster 69: Skin cancer - ECM organization | Cluster 80: Oligodendrocytes - Myelination | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in many | 53 | Cancer enriched | Detected in some | 7 | Group enriched | Detected in many | 23 | Cell type enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,336 | 8 |
ENSG00000123561 | SERPINA7 | Serpin family A member 7 | [
"P05543"
] | X | 106032435-106038727 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002803"
] | [
"TBG"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"Transport"
] | null | Approved | null | null | null | null | null | null | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in single | 608 | Cancer enriched | Detected in single | 18 | Cancer enriched | Detected in single | 201 | Cell type enriched | Detected in some | 23 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 5,337 | 9 |
ENSG00000123562 | MORF4L2 | Mortality factor 4 like 2 | [
"Q15014"
] | X | 103675496-103688158 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031872",
"HPA054102"
] | [
"KIAA0026",
"MRGX"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair",
"Growth regulation",
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Supported | null | 101 | null | Yes | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 23: Choroid plexus - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 5,338 | 4 |
ENSG00000123569 | H2BW1 | H2B.W histone 1 | [
"Q7Z2G1"
] | X | 104011147-104013708 | Evidence at protein level | No human protein/transcript evidence | Evidence at protein level | Evidence at protein level | [
"HPA056289"
] | [
"H2BFWT",
"TH2B-175"
] | [
"Predicted intracellular proteins"
] | [] | [
"DNA-binding"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 9 | null | null | null | null | Cluster 56: Non-specific - Sensory perception | Cluster 106: Spermatogonia - Spermatogonial differentiation | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,339 | 3 |
ENSG00000123572 | NRK | Nik related kinase | [
"Q7Z2Y5"
] | X | 105822539-105958610 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA017238"
] | [
"DKFZp686A17109"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | 5,341 | 6 |
ENSG00000123575 | FAM199X | Family with sequence similarity 199, X-linked | [
"Q6PEV8"
] | X | 104166453-104195902 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003093"
] | [
"CXorf39"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Approved | null | 5 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 19: Astrocytes - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 89: Adipocytes - Lipid metabolism | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in single | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 5,342 | 4 |
ENSG00000123576 | ESX1 | ESX homeobox 1 | [
"Q8N693"
] | X | 104250038-104254933 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051992",
"HPA073330"
] | [
"ESX1L",
"ESXR1"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Enhanced | null | null | null | null | null | null | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 106: Spermatogonia - Spermatogonial differentiation | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in single | 69 | Cancer enriched | Detected in some | 4 | Cancer enriched | Detected in single | 6 | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,343 | 6 |
ENSG00000123584 | MAGEA9 | MAGE family member A9 | [
"P43362"
] | X | 149781930-149787737 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045401",
"HPA051687"
] | [
"CT1.9",
"MAGE9",
"MGC8421"
] | [
"Predicted intracellular proteins"
] | [] | [
"Tumor antigen"
] | [] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | [] | Approved | null | null | 8 | null | null | null | null | Cluster 51: Myeloma - Immunoglobulins | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in single | 38 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in single | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,344 | 5 |
ENSG00000123594 | ATXN3L | Ataxin 3 like | [
"Q9H3M9"
] | X | 13318647-13320053 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024123",
"HPA027539"
] | [
"MJDL"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 3 | null | null | null | null | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 6: Testis - Spermatogenesis | Tissue enriched | Detected in single | 40 | Cancer enhanced | Detected in single | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,345 | 2 |
ENSG00000123595 | RAB9A | RAB9A, member RAS oncogene family | [
"P51151"
] | X | 13689128-13710504 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003094",
"CAB016411"
] | [
"RAB9"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Uncertain | Supported | null | 107 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 55: Lymphoma - Immune response | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,346 | 8 |
ENSG00000123600 | METTL8 | Methyltransferase 8, methylcytidine | [] | 2 | 171315746-171434802 | Evidence at transcript level | Evidence at transcript level | null | null | [
"HPA035421"
] | [
"FLJ13984",
"TIP"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 9: Non-specific - Receptor signaling | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 17: Non-specific - RNA processing | Cluster 81: Squamous epithelium - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma",
"Thyroid Carcinoma"
] | 5,347 | 4 |
ENSG00000123607 | TTC21B | Tetratricopeptide repeat domain 21B | [
"Q7Z4L5"
] | 2 | 165857475-165953851 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA073293"
] | [
"FAP60",
"FLA17",
"FLJ11457",
"IFT139",
"IFT139B",
"JBTS11",
"NPHP12",
"THM1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Ciliopathy",
"Disease variant",
"Intellectual disability",
"Joubert syndrome",
"Meckel syndrome",
"Nephronophthisis",
"Obesity"
] | [
"Primary cilium",
"Centriolar satellite",
"Basal body"
] | [
"Cytosol",
"Connecting piece",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Approved | Supported | null | 16 | null | No | Cluster 14: Non-specific - Unknown function | Cluster 2: Neurons - Nucleosome | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,348 | 6 |
ENSG00000123609 | NMI | N-myc and STAT interactor | [
"Q13287"
] | 2 | 151270470-151289894 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008588"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Host-virus interaction",
"Immunity",
"Innate immunity"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Immunity"
] | Supported | Approved | null | 53 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 39: Astrocytes - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,349 | 2 |
ENSG00000123612 | ACVR1C | Activin A receptor type 1C | [
"Q8NER5"
] | 2 | 157526767-157628864 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007982",
"HPA011933"
] | [
"ACVRLK7",
"ALK7"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [
"Kinase",
"Receptor",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Receptor"
] | null | Uncertain | null | null | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 89: Adipocytes - Lipid metabolism | Cluster 14: Adipose tissue - Angiogenesis | Tissue enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,351 | 7 |
ENSG00000123636 | BAZ2B | Bromodomain adjacent to zinc finger domain 2B | [
"Q9UIF8"
] | 2 | 159318979-159616569 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019819",
"HPA059292"
] | [
"WALp4"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 12 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 13: Oligodendrocytes - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Group enriched | Detected in all | 5 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,352 | 1 |
ENSG00000123684 | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1 | [
"Q92604"
] | 1 | 211743457-211830763 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"FAM34A",
"FAM34A1",
"KIAA0205",
"LPLAT7",
"NET8"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | null | null | 18 | null | null | Cluster 41: Basophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 1: Neuronal - Visual perception | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 5,354 | 1 |
ENSG00000123685 | BATF3 | Basic leucine zipper ATF-like transcription factor 3 | [
"Q9NR55"
] | 1 | 212686417-212699840 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA075858"
] | [
"JDP1",
"JUNDM1",
"SNFT"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoli"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | null | null | 37 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 23: Choroid plexus - Mixed function | Cluster 50: Lymphoma - Unknown function | Cluster 82: Dendritic cells - Antigen presentation | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in many | null | Group enriched | Detected in all | 6 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 0 | 0 | 0 | [] | [] | [] | 5,355 | 1 |
ENSG00000123700 | KCNJ2 | Potassium inwardly rectifying channel subfamily J member 2 | [
"P63252"
] | 17 | 70168673-70180044 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029109"
] | [
"IRK1",
"Kir2.1",
"LQT7"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Voltage-gated channel"
] | [
"Atrial fibrillation",
"Disease variant",
"FDA approved drug targets",
"Long QT syndrome",
"Short QT syndrome"
] | [] | [] | [] | [] | null | Approved | null | 10 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 4 | 0 | 0 | 0 | [] | [] | [] | 5,357 | 9 |
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