ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000128271 | ADORA2A | Adenosine A2a receptor | [
"P29274"
] | 22 | 24417879-24442357 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001943",
"HPA065566",
"HPA075997"
] | [
"ADORA2",
"RDC8"
] | [
"Cancer-related genes",
"FDA approved drug targets",
"G-protein coupled receptors",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Vesicles",
"Primary cilium"
] | [] | [] | Approved | Enhanced | Supported | 16 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 33: Neurons - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in some | 4 | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,916 | 2 |
ENSG00000128272 | ATF4 | Activating transcription factor 4 | [
"P18848"
] | 22 | 39519695-39522683 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011596",
"HPA062987"
] | [
"CREB-2",
"TAXREB67",
"TXREB"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 77 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 28: Oligodendrocytes - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 15: Non-specific - Protein processing | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 5,917 | 6 |
ENSG00000128274 | A4GALT | Alpha 1,4-galactosyltransferase (P blood group) | [
"Q9NPC4"
] | 22 | 42692121-42721298 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001141"
] | [
"A14GALT",
"Gb3S",
"P(k)",
"P1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Uncertain | null | null | 2 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,918 | 6 |
ENSG00000128276 | RFPL3 | Ret finger protein like 3 | [
"O75679"
] | 22 | 32354885-32361161 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048320",
"HPA072380"
] | [
"RNF120"
] | [
"Predicted intracellular proteins"
] | [
"Host-virus interaction"
] | [] | [] | [
"Nuclear speckles"
] | [
"Plasma membrane"
] | [] | [] | Approved | null | null | 8 | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 10 | Cancer enhanced | Detected in single | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,919 | 3 |
ENSG00000128283 | CDC42EP1 | CDC42 effector protein 1 | [
"Q00587"
] | 22 | 37560480-37569405 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006379",
"HPA076536"
] | [
"Borg5",
"CEP1",
"MSE55"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm",
"Actin filaments"
] | [] | [] | Supported | Approved | null | 20 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 11: White matter - Signal transduction | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 8 | 0 | 0 | 0 | [] | [] | [] | 5,920 | 9 |
ENSG00000128284 | APOL3 | Apolipoprotein L3 | [
"O95236"
] | 22 | 36140329-36166177 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"APOLIII",
"CG12-1"
] | [
"Predicted intracellular proteins"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Apolipoprotein"
] | null | null | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 47: Endothelial cells - Vasculature | Cluster 31: Non-specific - Antiviral immune response | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,921 | 2 |
ENSG00000128285 | MCHR1 | Melanin concentrating hormone receptor 1 | [
"Q99705"
] | 22 | 40679273-40682812 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"GPR24",
"MCH1R",
"SLC1"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 65: Brain - Transcription | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in some | 4 | Group enriched | Detected in some | 7 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,922 | 1 |
ENSG00000128294 | TPST2 | Tyrosylprotein sulfotransferase 2 | [
"O60704"
] | 22 | 26521996-26596717 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021054"
] | [
"TANGO13B"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Transferase"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Enhanced | null | 44 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 15: Kidney cancer - Membrane components | Cluster 47: Platelets - Hemostasis | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 5,923 | 2 |
ENSG00000128298 | BAIAP2L2 | BAR/IMD domain containing adaptor protein 2 like 2 | [
"Q6UXY1"
] | 22 | 38084652-38111015 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003043"
] | [
"FLJ22582",
"pinkbar"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 69: Skin cancer - ECM organization | Cluster 84: Apical squamous epithelium - Cornification | Cluster 77: Intestine - Digestion | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 5,924 | 2 |
ENSG00000128309 | MPST | Mercaptopyruvate sulfurtransferase | [
"P25325"
] | 22 | 37019635-37029821 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001240"
] | [
"MST",
"TST2",
"TUM1"
] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Transferase"
] | [] | [
"Mitochondria"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 25: Non-specific - Ribosome | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 5,925 | 5 |
ENSG00000128310 | GALR3 | Galanin receptor 3 | [
"O60755"
] | 22 | 37823382-37825485 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 70: DU4475 - Unknown function | Cluster 98: Neurons - Neurotransmission & signaling | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,926 | 6 |
ENSG00000128313 | APOL5 | Apolipoprotein L5 | [
"Q9BWW9"
] | 22 | 35717872-35729483 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [] | [
"APOLV"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Lipid transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | null | Cluster 46: Lymphoma - Humoral immune response | Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,928 | 2 |
ENSG00000128335 | APOL2 | Apolipoprotein L2 | [
"Q9BQE5"
] | 22 | 36226209-36239954 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001078",
"CAB026695"
] | [
"APOL-II"
] | [
"Cancer-related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid transport",
"Transport"
] | [] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Supported | null | 27 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 24: Neurons - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 5,930 | 1 |
ENSG00000128340 | RAC2 | Rac family small GTPase 2 | [
"P15153"
] | 22 | 37225270-37259594 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022946",
"HPA047820"
] | [
"EN-7"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Hydrolase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 18 | null | Yes | Cluster 35: Neutrophils - Protein binding | Cluster 12: Non-specific - Vasculature | Cluster 49: HMC-1 - Innate immune response | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 66: Lymphoid tissue - Immune response | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 5,931 | 4 |
ENSG00000128342 | LIF | LIF interleukin 6 family cytokine | [
"P15018"
] | 22 | 30240453-30246759 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018844",
"CAB025985"
] | [
"CDF",
"DIA",
"HILDA"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Cytokine",
"Growth factor"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [
"Secreted in other tissues"
] | [
"Cytokine"
] | Supported | Uncertain | null | 5 | null | null | null | Cluster 12: Non-specific - Vasculature | Cluster 69: Skin cancer - ECM organization | Cluster 17: Non-specific - RNA processing | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,932 | 8 |
ENSG00000128346 | C22orf23 | Chromosome 22 open reading frame 23 | [
"Q9BZE7"
] | 22 | 37943050-37953669 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000650"
] | [
"EVG1",
"FLJ32787",
"LOC84645"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 6 | null | null | null | Cluster 26: Oligodendrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 47: Testis - Mixed function | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,933 | 8 |
ENSG00000128394 | APOBEC3F | Apolipoprotein B mRNA editing enzyme catalytic subunit 3F | [
"Q8IUX4"
] | 22 | 39040604-39055972 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA073637"
] | [
"ARP8",
"BK150C2.4.MRNA",
"KA6"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Host-virus interaction",
"Immunity",
"Innate immunity"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Uncertain | null | null | 26 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 18: Lymphoid tissue - Immune response | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 5,935 | 8 |
ENSG00000128408 | RIBC2 | RIB43A domain with coiled-coils 2 | [
"Q9H4K1"
] | 22 | 45413693-45432509 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA003210"
] | [
"C22orf11",
"DKFZp566F0546",
"FLJ25720"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Connecting piece",
"Mid piece",
"Principal piece",
"End piece"
] | [
"Perinuclear theca",
"Calyx"
] | [] | [] | Approved | Approved | null | 3 | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Group enriched | Detected in some | 9 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Ovary Serous Cystadenocarcinoma"
] | 5,936 | 1 |
ENSG00000128422 | KRT17 | Keratin 17 | [
"Q04695"
] | 17 | 41619442-41624842 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000029",
"HPA000452",
"HPA000453",
"HPA000539",
"HPA045062"
] | [
"PCHC1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Cancer-related genes",
"Disease variant",
"Ectodermal dysplasia",
"Palmoplantar keratoderma"
] | [
"Intermediate filaments"
] | [] | [] | [] | Enhanced | Enhanced | null | 26 | Yes | No | null | Cluster 53: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 26: Keratinocytes - Keratinization | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 0 | 5 | [
"Breast Invasive Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,937 | 8 |
ENSG00000128463 | EMC4 | ER membrane protein complex subunit 4 | [
"Q5J8M3"
] | 15 | 34225013-34230156 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA053440"
] | [
"FLJ90746",
"MGC24415",
"PIG17",
"TMEM85"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Apoptosis"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 79 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Lung Adenocarcinoma"
] | 5,938 | 6 |
ENSG00000128482 | RNF112 | Ring finger protein 112 | [
"Q9ULX5"
] | 17 | 19411125-19417276 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA015970"
] | [
"BFP",
"ZNF179"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Neurogenesis",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Enhanced | null | 21 | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in many | 8 | Cancer enriched | Detected in some | 5 | Cancer enriched | Detected in some | 9 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 5,939 | 1 |
ENSG00000128487 | SPECC1 | Sperm antigen with calponin homology and coiled-coil domains 1 | [
"Q5M775"
] | 17 | 20008865-20319026 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021421",
"HPA021430",
"HPA061073"
] | [
"CYTSB",
"FLJ36955",
"HCMOGT-1",
"NSP"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Proto-oncogene"
] | [
"Nucleoplasm",
"Vesicles"
] | [
"Nucleoli fibrillar center",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 10 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 34: Non-specific - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 82: Dendritic cells - Antigen presentation | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 5,940 | 3 |
ENSG00000128513 | POT1 | Protection of telomeres 1 | [
"Q9NUX5"
] | 7 | 124822386-124929983 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA068538"
] | [
"DKFZp586D211",
"hPot1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 60 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 39: Non-specific - Transcription | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,943 | 9 |
ENSG00000128519 | TAS2R16 | Taste 2 receptor member 16 | [
"Q9NYV7"
] | 7 | 122994704-122995700 | Evidence at protein level | No human protein/transcript evidence | Evidence at protein level | Evidence at protein level | [] | [
"T2R16"
] | [
"G-protein coupled receptors",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Sensory transduction",
"Taste"
] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | null | null | null | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,944 | 4 |
ENSG00000128524 | ATP6V1F | ATPase H+ transporting V1 subunit F | [
"Q16864"
] | 7 | 128862856-128865847 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009529",
"HPA048700",
"HPA062011"
] | [
"ATP6S14",
"VATF",
"Vma7"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Hydrogen ion transport",
"Ion transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Supported | null | 64 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 39: Non-specific - Transcription | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 5,945 | 8 |
ENSG00000128534 | LSM8 | LSM8 homolog, U6 small nuclear RNA associated | [
"O95777"
] | 7 | 118184144-118204035 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA020116"
] | [
"YJR022W"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | 43 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 25: Non-specific - Transcription | Cluster 39: Non-specific - Transcription | Cluster 15: Non-specific - Protein processing | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 5,946 | 1 |
ENSG00000128536 | CDHR3 | Cadherin related family member 3 | [
"Q6ZTQ4"
] | 7 | 105876796-106036432 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011218"
] | [
"CDH28",
"FLJ23834",
"FLJ44366"
] | [
"Disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [
"Asthma"
] | [] | [] | [] | [] | null | Supported | null | 6 | null | null | Cluster 34: B-cells - Unknown function | Cluster 17: Choroid plexus - Cilium | Cluster 46: Lymphoma - Humoral immune response | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 48: Ciliated tissues - Cilium organization | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 5,947 | 6 |
ENSG00000128563 | PRKRIP1 | PRKR interacting protein 1 | [
"Q9H875"
] | 7 | 102363872-102426676 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051146"
] | [
"C114",
"FLJ13902",
"KRBOX3"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Actin filaments"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 4 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 15: Non-specific - Transcription | Cluster 39: Non-specific - Transcription | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 5,948 | 3 |
ENSG00000128564 | VGF | VGF nerve growth factor inducible | [
"O15240"
] | 7 | 101162509-101165569 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055177",
"HPA072505"
] | [
"SCG7",
"SgVII"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Antibiotic",
"Antimicrobial",
"Growth factor"
] | [] | [
"Golgi apparatus",
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Growth factor"
] | Enhanced | Enhanced | null | 16 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 78: Brain - Neuronal signaling | Group enriched | Detected in some | 8 | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in many | 6 | Cell type enriched | Detected in some | 8 | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Prostate Adenocarcinoma"
] | 5,949 | 8 |
ENSG00000128567 | PODXL | Podocalyxin like | [
"O00592"
] | 7 | 131500262-131558217 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002110",
"CAB016169",
"HPA045507",
"CAB062558",
"CAB068219",
"CAB068220"
] | [
"gp135",
"Gp200",
"PC",
"PCLP",
"PDX",
"PODXL1"
] | [
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Cell adhesion"
] | [] | [] | [
"Endoplasmic reticulum",
"Plasma membrane"
] | [
"Nucleoli",
"Vesicles",
"Centriolar satellite"
] | [] | [] | Approved | Enhanced | null | 10 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 34: Testis cancer - Unknown function | Cluster 57: Podocytes - Glomerular filtration | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 6 | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 5,950 | 3 |
ENSG00000128578 | STRIP2 | Striatin interacting protein 2 | [
"Q9ULQ0"
] | 7 | 129434432-129488399 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA019657"
] | [
"FAM40B",
"FAR11B",
"KIAA1170"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 22 | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 99: Retinal pigment epithelial cells - Retinol metabolism | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 5,952 | 7 |
ENSG00000128581 | IFT22 | Intraflagellar transport 22 | [
"Q9H7X7"
] | 7 | 101310914-101321823 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042930"
] | [
"DKFZp761N0823",
"FAP9",
"FLJ13225",
"FLJ14117",
"RABL5"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Microtubules",
"Cytosol"
] | [
"Mitotic spindle",
"Primary cilium",
"Basal body",
"Flagellar centriole",
"Mid piece",
"Principal piece",
"End piece"
] | [] | [] | Approved | Approved | null | 56 | Yes | null | Cluster 24: Non-specific - Transcription | Cluster 23: Choroid plexus - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 5,953 | 6 |
ENSG00000128585 | MKLN1 | Muskelin 1 | [
"Q9UL63"
] | 7 | 131110096-131496632 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA022817",
"HPA041810"
] | [
"TWA2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Approved | Approved | null | 68 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 39: Non-specific - Transcription | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Immune cell enriched | Detected in many | 6 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,954 | 4 |
ENSG00000128590 | DNAJB9 | DnaJ heat shock protein family (Hsp40) member B9 | [
"Q9UBS3"
] | 7 | 108569867-108574850 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040967",
"HPA041553"
] | [
"MDG1"
] | [
"Predicted intracellular proteins"
] | [
"Unfolded protein response"
] | [
"Chaperone"
] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [
"Intracellular and membrane"
] | [
"Other"
] | Approved | Supported | null | 65 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 63: Non-specific - Protein processing | Cluster 103: Non-specific - Basic cellular processes | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,955 | 8 |
ENSG00000128591 | FLNC | Filamin C | [
"Q14315"
] | 7 | 128830406-128859274 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006135",
"HPA071007"
] | [
"ABP-280",
"ABPL",
"FLN2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Actin-binding"
] | [
"Cardiomyopathy",
"Disease variant",
"Myofibrillar myopathy"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 42 | null | null | null | Cluster 22: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 5 | 0 | 5 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 5,956 | 4 |
ENSG00000128594 | LRRC4 | Leucine rich repeat containing 4 | [
"Q9HBW1"
] | 7 | 128027071-128032107 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051100"
] | [
"NAG14"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | null | null | 4 | null | null | Cluster 4: Neutrophils - Degranulation | Cluster 53: Neurons - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 5 | 5 | 0 | 5 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 5,957 | 9 |
ENSG00000128595 | CALU | Calumenin | [
"O43852"
] | 7 | 128739292-128773400 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006018",
"HPA071040"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Enhanced | Supported | null | 25 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 12: Non-specific - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 8: Non-specific - Secretory pathway | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 5 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 5,958 | 3 |
ENSG00000128596 | CCDC136 | Coiled-coil domain containing 136 | [
"Q96JN2"
] | 7 | 128790757-128822132 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010646",
"HPA071015"
] | [
"DKFZP434G156",
"KIAA1793",
"NAG6"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Differentiation",
"Fertilization",
"Spermatogenesis"
] | [] | [] | [
"Plasma membrane"
] | [
"Golgi apparatus",
"Vesicles",
"Mid piece"
] | [] | [] | Approved | Enhanced | Approved | 9 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 67: Testis - Mixed function | Group enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,959 | 7 |
ENSG00000128602 | SMO | Smoothened, frizzled class receptor | [
"Q99835"
] | 7 | 129188633-129213545 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011446",
"CAB080590"
] | [
"FZD11",
"SMOH"
] | [
"Cancer-related genes",
"Disease related genes",
"FDA approved drug targets",
"G-protein coupled receptors",
"Human disease related genes",
"Plasma proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [
"Developmental protein",
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets"
] | [
"Golgi apparatus",
"Plasma membrane",
"Primary cilium"
] | [] | [] | [] | Supported | Approved | null | 3 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 5: Rhabdoid - Unknown function | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Skin Cutaneous Melanoma"
] | [
"Skin Cutaneous Melanoma"
] | 5,960 | 6 |
ENSG00000128606 | LRRC17 | Leucine rich repeat containing 17 | [
"Q8N6Y2"
] | 7 | 102913000-102945111 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA073458"
] | [
"H_RG318M05.3",
"P37NB"
] | [
"Predicted secreted proteins"
] | [
"Osteogenesis"
] | [] | [] | [
"Vesicles"
] | [
"Cytokinetic bridge"
] | [
"Secreted in other tissues"
] | [
"Other"
] | Approved | null | null | 9 | Yes | null | Cluster 22: Eosinophils - Transcription | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 33: Sarcoma - Muscle contraction | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 94 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,962 | 3 |
ENSG00000128607 | KLHDC10 | Kelch domain containing 10 | [
"Q6PID8"
] | 7 | 130070534-130135705 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA020119"
] | [
"KIAA0265",
"slim"
] | [
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 36: Eosinophils - Protein ubiquitination | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 39: Non-specific - Transcription | Cluster 7: Non-specific - Transcription | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in single | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 5,963 | 7 |
ENSG00000128609 | NDUFA5 | NADH:ubiquinone oxidoreductase subunit A5 | [
"Q16718"
] | 7 | 123536997-123557904 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043175",
"HPA054868"
] | [
"B13",
"CI-13kB",
"CI-13KD-B",
"NUFM",
"UQOR13"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Electron transport",
"Respiratory chain",
"Transport"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Supported | null | 41 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 14: Neurons - Synaptic function | Cluster 39: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,964 | 4 |
ENSG00000128610 | FEZF1 | FEZ family zinc finger 1 | [
"A0PJY2"
] | 7 | 122301303-122310691 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064639",
"HPA073693"
] | [
"ZNF312B"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding",
"Repressor"
] | [
"Disease variant",
"Hypogonadotropic hypogonadism",
"Kallmann syndrome"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 6 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 12: Bone cancer - Neuronal signaling | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in many | 8 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Lung Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Lung Squamous Cell Carcinoma"
] | 5,965 | 2 |
ENSG00000128617 | OPN1SW | Opsin 1, short wave sensitive | [
"P03999"
] | 7 | 128772485-128775794 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013562",
"HPA014083"
] | [
"BCP",
"BOP",
"CBT"
] | [
"Disease related genes",
"G-protein coupled receptors",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Sensory transduction",
"Vision"
] | [
"G-protein coupled receptor",
"Photoreceptor protein",
"Receptor",
"Retinal protein",
"Transducer"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | null | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in single | 181 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 8 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,966 | 2 |
ENSG00000128626 | MRPS12 | Mitochondrial ribosomal protein S12 | [
"O15235"
] | 19 | 38930944-38933168 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046775",
"HPA050633"
] | [
"RPMS12",
"RPS12",
"RPSM12"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 24 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 27: Non-specific - Mixed function | Cluster 4: Non-specific - Transcription | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 4 | 2 | 3 | [
"Kidney Chromophobe"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 5,967 | 6 |
ENSG00000128641 | MYO1B | Myosin IB | [
"O43795"
] | 2 | 191245185-191425389 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA013607",
"HPA060144"
] | [
"myr1"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Calmodulin-binding",
"Motor protein",
"Myosin"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Enhanced | Approved | null | 44 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 110: Mural cells - ECM organization | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 5,968 | 6 |
ENSG00000128645 | HOXD1 | Homeobox D1 | [
"Q9GZZ0"
] | 2 | 176188668-176190907 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA040062",
"HPA056900"
] | [
"HOX4",
"HOX4G"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | null | null | null | null | Cluster 30: White matter - Myelination | Cluster 15: Kidney cancer - Membrane components | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,969 | 9 |
ENSG00000128656 | CHN1 | Chimerin 1 | [
"P15882"
] | 2 | 174798809-175005381 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036111"
] | [
"ARHGAP2",
"CHN",
"DURS2",
"n-chimerin",
"RhoGAP2"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Neurogenesis"
] | [
"GTPase activation"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | null | null | 6 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 53: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in many | 19 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 4 | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,973 | 7 |
ENSG00000128683 | GAD1 | Glutamate decarboxylase 1 | [
"Q99259"
] | 2 | 170813213-170861151 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004415",
"HPA048871",
"HPA058412",
"CAB078176"
] | [
"GAD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Neurotransmitter biosynthesis"
] | [
"Decarboxylase",
"Lyase"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Vesicles",
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | Supported | 7 | null | null | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 32: Non-specific - Cell proliferation | Cluster 109: Neurons - Neuronal signaling | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in many | 8 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 5,974 | 8 |
ENSG00000128694 | OSGEPL1 | O-sialoglycoprotein endopeptidase like 1 | [
"Q9H4B0"
] | 2 | 189746660-189763227 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030693"
] | [
"OSGEPL",
"Qri7"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"tRNA processing"
] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Supported | Uncertain | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,975 | 7 |
ENSG00000128699 | ORMDL1 | ORMDL sphingolipid biosynthesis regulator 1 | [
"Q9P0S3"
] | 2 | 189770267-189784364 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065643"
] | [] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | null | null | 33 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 50: Non-specific - Nucleic acid binding | Cluster 56: Non-specific - Sensory perception | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 5,976 | 5 |
ENSG00000128708 | HAT1 | Histone acetyltransferase 1 | [
"O14929"
] | 2 | 171922448-171983686 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036788",
"CAB037191"
] | [
"KAT1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 57 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 55: Non-specific - Transcription | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 5,977 | 4 |
ENSG00000128709 | HOXD9 | Homeobox D9 | [
"P28356"
] | 2 | 176122719-176124937 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA068683"
] | [
"HOX4",
"HOX4C"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | [] | Supported | null | null | null | null | null | null | Cluster 22: Non-specific - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 5,978 | 4 |
ENSG00000128710 | HOXD10 | Homeobox D10 | [
"P28358"
] | 2 | 176108790-176119937 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA065871"
] | [
"HOX4",
"HOX4D"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Cytosol",
"Cytoplasmic bodies"
] | [] | [] | Approved | null | null | 9 | No | null | null | null | Cluster 12: Bone cancer - Neuronal signaling | Cluster 105: Non-specific - Mixed function | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 5,979 | 8 |
ENSG00000128713 | HOXD11 | Homeobox D11 | [
"P31277"
] | 2 | 176104216-176109754 | Evidence at protein level | Evidence at protein level | No human protein/transcript evidence | Evidence at protein level | [
"HPA055155"
] | [
"HOX4",
"HOX4F"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | null | null | null | null | null | Cluster 12: Bone cancer - Neuronal signaling | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,980 | 3 |
ENSG00000128714 | HOXD13 | Homeobox D13 | [
"P35453"
] | 2 | 176092721-176095944 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA064064"
] | [
"HOX4I",
"SPD"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | null | null | 1 | null | null | null | null | Cluster 12: Bone cancer - Neuronal signaling | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 8 | Cancer enriched | Detected in many | 5 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 5,981 | 4 |
ENSG00000128731 | HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | [
"O95714"
] | 15 | 28111040-28322179 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017188",
"HPA048389",
"HPA074166"
] | [
"D15F37S1",
"jdf2",
"p528"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"DNA damage",
"DNA repair",
"Ubl conjugation pathway"
] | [
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 104 | null | null | null | Cluster 14: Neurons - Synaptic function | Cluster 58: Non-specific - Nuclear processes | Cluster 102: Non-specific - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,982 | 4 |
ENSG00000128739 | SNRPN | Small nuclear ribonucleoprotein polypeptide N | [
"P63162"
] | 15 | 24823637-24978723 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003482",
"HPA067842"
] | [
"HCERN3",
"PWCR",
"RT-LI",
"SM-D",
"SMN",
"SNRNP-N",
"SNURF-SNRPN"
] | [
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 78 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 1: Neurons - Mixed function | Cluster 34: Testis cancer - Unknown function | Cluster 109: Neurons - Neuronal signaling | Cluster 35: Non-specific - Mixed function | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 5,983 | 1 |
ENSG00000128789 | PSMG2 | Proteasome assembly chaperone 2 | [
"Q969U7"
] | 18 | 12658043-12728945 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041517",
"HPA046741"
] | [
"CLAST3",
"HCCA3",
"HsT1707",
"MDS003",
"MGC15092",
"PAC2",
"TNFSF5IP1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Chaperone"
] | [] | [
"Nuclear bodies"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 64 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 9: Non-specific - Receptor signaling | Cluster 13: Non-specific - Mixed function | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 5,984 | 8 |
ENSG00000128791 | TWSG1 | Twisted gastrulation BMP signaling modulator 1 | [
"Q9GZX9"
] | 18 | 9334767-9402420 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014898"
] | [
"TSG"
] | [
"Predicted secreted proteins"
] | [] | [
"Developmental protein"
] | [] | [
"Centrosome",
"Cytosol"
] | [] | [
"Secreted - unknown location"
] | [
"Developmental protein"
] | Supported | Uncertain | null | 10 | No | No | Cluster 30: Non-specific - DNA binding | Cluster 55: Non-specific - Transcription | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 38: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 5,985 | 8 |
ENSG00000128805 | ARHGAP22 | Rho GTPase activating protein 22 | [
"Q7Z5H3"
] | 10 | 48446036-48656265 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB020696",
"HPA040391",
"HPA064439"
] | [
"RhoGAP2"
] | [
"Predicted intracellular proteins"
] | [
"Angiogenesis",
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Developmental protein",
"GTPase activation"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Supported | Uncertain | null | 8 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 30: White matter - Myelination | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 3: Oligodendrocytes - Myelination | Tissue enriched | Detected in many | 5 | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 4 | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 5,986 | 6 |
ENSG00000128815 | WDFY4 | WDFY family member 4 | [
"Q6ZS81"
] | 10 | 48684873-48982956 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040634"
] | [
"C10orf64",
"Em:AC060234.3",
"FLJ45748",
"KIAA1607"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Autophagy"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 55: Lymphoma - Immune response | Cluster 82: Dendritic cells - Antigen presentation | Cluster 18: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 9 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 6 | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 5,987 | 4 |
ENSG00000128829 | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4 | [
"Q9P2K8"
] | 15 | 39934115-40035591 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011811"
] | [
"GCN2",
"KIAA1338"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Activation of host autophagy by virus",
"Adaptive immunity",
"Antiviral defense",
"Cell cycle",
"Growth arrest",
"Host-virus interaction",
"Immunity",
"Neurogenesis",
"Stress response",
"Translation regulation"
] | [
"Activator",
"Kinase",
"RNA-binding",
"Serine/threonine-protein kinase",
"Transferase",
"tRNA-binding"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 4 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [] | [
"Stomach Adenocarcinoma"
] | [
"Stomach Adenocarcinoma"
] | 5,988 | 1 |
ENSG00000128849 | CGNL1 | Cingulin like 1 | [
"Q0VF96"
] | 15 | 57375967-57550717 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB013500",
"HPA056911",
"HPA069214"
] | [
"FLJ14957",
"JACOP",
"KIAA1749",
"PCING"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cell Junctions"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Enhanced | null | 10 | No | No | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 15: Kidney cancer - Membrane components | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 5,990 | 3 |
ENSG00000128872 | TMOD2 | Tropomodulin 2 | [
"Q9NZR1"
] | 15 | 51751597-51816363 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041365"
] | [
"NTMOD"
] | [
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Enhanced | null | 9 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 61: Schwann cells & Melanocytes - Mixed function | Cluster 73: Brain - Neuronal signaling | Tissue enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 5,991 | 4 |
ENSG00000128881 | TTBK2 | Tau tubulin kinase 2 | [
"Q6IQ55"
] | 15 | 42738730-42920809 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018113"
] | [
"KIAA0847",
"SCA11"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [
"Neurodegeneration",
"Spinocerebellar ataxia"
] | [
"Microtubules",
"Cytosol"
] | [
"Primary cilium",
"Primary cilium transition zone",
"Basal body"
] | [] | [] | Supported | Approved | null | 9 | null | null | Cluster 24: Non-specific - Transcription | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 58: Non-specific - Nuclear processes | Cluster 109: Neurons - Neuronal signaling | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cell type specificity | Detected in all | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe"
] | [
"Colon Adenocarcinoma",
"Kidney Chromophobe"
] | 5,992 | 8 |
ENSG00000128891 | CCDC32 | Coiled-coil domain containing 32 | [
"Q9BV29"
] | 15 | 40528683-40565054 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041360",
"HPA041688"
] | [
"C15orf57",
"MGC20481"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [] | [
"Ciliopathy"
] | [
"Plasma membrane"
] | [
"Microtubules",
"Primary cilium",
"Centrosome",
"Basal body"
] | [] | [] | Approved | Uncertain | null | 6 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 51: Myeloma - Immunoglobulins | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,994 | 9 |
ENSG00000128915 | ICE2 | Interactor of little elongation complex ELL subunit 2 | [
"Q659A1"
] | 15 | 60419609-60479160 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040058"
] | [
"BRCC1",
"FLJ11896",
"NARG2"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 15 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 50: Non-specific - Nucleic acid binding | Cluster 58: Non-specific - Nuclear processes | Cluster 55: Myocytes - Oxidative muscle function | Cluster 69: Parathyroid gland - Mixed function | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 5,996 | 5 |
ENSG00000128917 | DLL4 | Delta like canonical Notch ligand 4 | [
"Q9NR61"
] | 15 | 40929340-40939073 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023392"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Angiogenesis",
"Differentiation",
"Neurogenesis",
"Notch signaling pathway",
"Sensory transduction",
"Vision"
] | [
"Developmental protein"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 10: Ciliated cells - Ion channel activity | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 5,997 | 4 |
ENSG00000128918 | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2 | [
"O94788"
] | 15 | 57953424-58497866 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010022"
] | [
"RALDH2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 14 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 29: Forebrain - Mixed function | Cluster 59: Leukemia - T-cell receptor | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 15 | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 5,998 | 8 |
ENSG00000128923 | MINDY2 | MINDY lysine 48 deubiquitinase 2 | [
"Q8NBR6"
] | 15 | 58771192-58861900 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051103",
"HPA063669"
] | [
"FAM63B",
"KIAA1164"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 1 | No | No | Cluster 20: Non-specific - DNA binding | Cluster 25: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 5,999 | 9 |
ENSG00000128928 | IVD | Isovaleryl-CoA dehydrogenase | [
"P26440"
] | 15 | 40405485-40435947 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041391",
"HPA044250"
] | [
"ACAD2",
"IVDH"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 19 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 46: Brainstem - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 6,000 | 1 |
ENSG00000128944 | KNSTRN | Kinetochore localized astrin (SPAG5) binding protein | [
"Q9Y448"
] | 15 | 40382721-40394288 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042027"
] | [
"C15orf23",
"FLJ14502",
"kinastrin",
"SKAP",
"TRAF4AF1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [
"Disease variant"
] | [
"Mitotic spindle",
"Centriolar satellite"
] | [
"Plasma membrane"
] | [] | [] | Enhanced | Enhanced | null | 40 | Yes | Yes | Cluster 40: Monocytes - Innate immune response | Cluster 34: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 11 | Low immune cell specificity | Detected in all | null | 5 | 4 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 6,001 | 3 |
ENSG00000128965 | CHAC1 | ChaC glutathione specific gamma-glutamylcyclotransferase 1 | [
"Q9BUX1"
] | 15 | 40952962-40956512 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042708",
"HPA043505"
] | [
"MGC4504"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Neurogenesis",
"Notch signaling pathway",
"Unfolded protein response"
] | [
"Lyase"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 4 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 13: Non-specific - Mixed function | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 24: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Lung Squamous Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 6,003 | 2 |
ENSG00000128973 | CLN6 | CLN6 transmembrane ER protein | [
"Q9NWW5"
] | 15 | 68206992-68257211 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066046",
"HPA066759"
] | [
"FLJ20561",
"HsT18960",
"nclf"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [
"Disease variant",
"Neurodegeneration",
"Neuronal ceroid lipofuscinosis"
] | [
"Endoplasmic reticulum"
] | [
"Nucleoli",
"Vesicles"
] | [] | [] | Approved | Approved | null | 36 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 28: Oligodendrocytes - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 80: Oligodendrocytes - Myelination | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,004 | 9 |
ENSG00000128989 | ARPP19 | CAMP regulated phosphoprotein 19 | [
"P56211"
] | 15 | 52547045-52569883 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056851"
] | [
"ARPP-16",
"ARPP-19",
"ARPP16",
"ENSAL"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Protein phosphatase inhibitor"
] | [] | [
"Vesicles",
"Basal body"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 33: Neurons - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in all | 6 | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,005 | 1 |
ENSG00000129003 | VPS13C | Vacuolar protein sorting 13 homolog C | [
"Q709C8"
] | 15 | 61852389-62060473 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043507"
] | [
"BLTP5C",
"FLJ10381",
"FLJ20136",
"KIAA1421"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Lipid transport",
"Transport"
] | [] | [
"Disease variant",
"Neurodegeneration",
"Parkinson disease",
"Parkinsonism"
] | [] | [] | [] | [] | null | Uncertain | null | 26 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 30: White matter - Myelination | Cluster 58: Non-specific - Nuclear processes | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 32: Retina & Lymphoid tissues - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,006 | 2 |
ENSG00000129007 | CALML4 | Calmodulin like 4 | [
"Q96GE6"
] | 15 | 68190705-68206079 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA051109"
] | [
"MGC4809",
"NY-BR-20"
] | [
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | null | Yes | No | Cluster 40: Monocytes - Innate immune response | Cluster 23: Choroid plexus - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 1: Choroid plexus - Transmembrane transport | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in some | 40 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,007 | 6 |
ENSG00000129009 | ISLR | Immunoglobulin superfamily containing leucine rich repeat | [
"O14498"
] | 15 | 74173710-74176872 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA040326",
"HPA050811"
] | [
"HsT17563"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Golgi apparatus"
] | [
"Secreted - unknown location"
] | [
"No annotated function"
] | Approved | Approved | null | 65 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 22: Non-specific - Basic cellular functions | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 6,008 | 1 |
ENSG00000129028 | THAP10 | THAP domain containing 10 | [
"Q9P2Z0"
] | 15 | 70881342-70892433 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041416",
"HPA073220"
] | [] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | 21 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 16: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 7 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,009 | 3 |
ENSG00000129048 | ACKR4 | Atypical chemokine receptor 4 | [
"Q9NPB9"
] | 3 | 132597270-132618967 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA054926"
] | [
"CCBP2",
"CCR11",
"CCRL1",
"CCX-CKR",
"PPR1",
"VSHK1"
] | [
"G-protein coupled receptors",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [] | [
"Vesicles",
"Mitochondria"
] | [] | [] | [] | Approved | null | null | null | null | null | null | Cluster 17: Choroid plexus - Cilium | Cluster 64: Connective tissue cells - ECM organization | Cluster 89: Adipocytes - Lipid metabolism | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 6,011 | 7 |
ENSG00000129071 | MBD4 | Methyl-CpG binding domain 4, DNA glycosylase | [
"O95243"
] | 3 | 129430947-129440179 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002031"
] | [
"MED1"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"DNA-binding",
"Hydrolase"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nuclear speckles"
] | [] | [] | [] | Supported | Supported | null | 11 | null | null | Cluster 18: Non-specific - Translation | Cluster 55: Non-specific - Transcription | Cluster 63: Non-specific - Protein processing | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 6,013 | 5 |
ENSG00000129083 | COPB1 | COPI coat complex subunit beta 1 | [
"P53618"
] | 11 | 14443440-14500027 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB012338",
"HPA043954",
"HPA064403"
] | [
"COPB"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Host-virus interaction",
"Protein transport",
"Transport"
] | [] | [
"Cataract",
"Disease variant",
"Intellectual disability"
] | [
"Golgi apparatus",
"Vesicles",
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | null | 72 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 24: Non-specific - Unknown function | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 6,014 | 6 |
ENSG00000129084 | PSMA1 | Proteasome 20S subunit alpha 1 | [
"P25786"
] | 11 | 14504874-14643635 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033765",
"HPA037646",
"HPA043891",
"CAB079995"
] | [
"HC2",
"MGC14542",
"MGC14575",
"MGC14751",
"MGC1667",
"MGC21459",
"MGC22853",
"MGC23915",
"NU",
"PROS30"
] | [
"Enzymes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Immunity"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies",
"Centrosome"
] | [] | [] | Supported | Supported | null | 284 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 14: Neurons - Synaptic function | Cluster 24: Non-specific - Unknown function | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 6,015 | 4 |
ENSG00000129103 | SUMF2 | Sulfatase modifying factor 2 | [
"Q8NBJ7"
] | 7 | 56064002-56080670 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024040",
"CAB025743",
"HPA074892"
] | [
"DKFZp566I1024"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Vesicles",
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Uncertain | Enhanced | null | 13 | Yes | No | Cluster 13: Non-specific - Mitochondria | Cluster 21: Non-specific - Metabolism | Cluster 67: Non-specific - Unknown function | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,016 | 7 |
ENSG00000129116 | PALLD | Palladin, cytoskeletal associated protein | [
"Q8WX93"
] | 4 | 168497052-168928457 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035905",
"CAB070159"
] | [
"CGI-151",
"KIAA0992",
"SIH002"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding"
] | [] | [
"Actin filaments"
] | [
"Plasma membrane",
"Mitochondria",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 14 | No | No | Cluster 42: Non-specific - Vesicular transport | Cluster 39: Astrocytes - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,017 | 5 |
ENSG00000129128 | SPCS3 | Signal peptidase complex subunit 3 | [
"P61009"
] | 4 | 176319966-176332245 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA053180"
] | [
"FLJ22649",
"PRO3567",
"SPC22/23",
"SPC3",
"YLR066W"
] | [
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 42 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 27: Non-specific - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 44: Plasma cells - Antibody production & secretion | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,018 | 6 |
ENSG00000129151 | BBOX1 | Gamma-butyrobetaine hydroxylase 1 | [
"O75936"
] | 11 | 27040725-27127809 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007600",
"HPA027823"
] | [
"BBH",
"BBOX",
"G-BBH",
"gamma-BBH"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Carnitine biosynthesis"
] | [
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Vesicles"
] | [
"Actin filaments"
] | [] | [] | Uncertain | Enhanced | Approved | 11 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in some | null | Group enriched | Detected in many | 9 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 6,019 | 5 |
ENSG00000129152 | MYOD1 | Myogenic differentiation 1 | [
"P15172"
] | 11 | 17719571-17722136 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055436",
"HPA078647"
] | [
"bHLHc1",
"MYF3",
"MYOD",
"PUM"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Myogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Cancer-related genes",
"Disease variant"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | 39 | null | null | null | null | Cluster 33: Sarcoma - Muscle contraction | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enriched | Detected in some | 10 | Cancer enriched | Detected in some | 65 | Cancer enhanced | Detected in single | null | Group enriched | Detected in some | 8 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,020 | 8 |
ENSG00000129158 | SERGEF | Secretion regulating guanine nucleotide exchange factor | [
"Q9UGK8"
] | 11 | 17788048-18013047 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037811",
"HPA037812",
"HPA074086"
] | [
"DelGEF",
"Gnefr"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 13 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 1: Neurons - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 6,021 | 2 |
ENSG00000129159 | KCNC1 | Potassium voltage-gated channel subfamily C member 1 | [
"P48547"
] | 11 | 17734774-17856804 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047634",
"HPA048249"
] | [
"Kv3.1"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Potassium channel",
"Voltage-gated channel"
] | [
"Disease variant",
"Epilepsy",
"FDA approved drug targets",
"Neurodegeneration"
] | [
"Nucleoplasm",
"Nuclear membrane"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 37: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in some | 15 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 5 | 0 | 0 | 0 | [] | [] | [] | 6,022 | 6 |
ENSG00000129167 | TPH1 | Tryptophan hydroxylase 1 | [
"P17752"
] | 11 | 18017555-18046269 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB010767",
"HPA022483"
] | [
"TPH",
"TPRH"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Serotonin biosynthesis"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"FDA approved drug targets"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 4 | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 10: Ciliated cells - Ion channel activity | Cluster 96: Enteroendocrine cells - Neuropeptide signaling | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 5 | Cancer enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 13 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,023 | 5 |
ENSG00000129170 | CSRP3 | Cysteine and glycine rich protein 3 | [
"P50461"
] | 11 | 19182030-19210571 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042581"
] | [
"CLP",
"CMD1M",
"MLP"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Myogenesis",
"Transcription",
"Transcription regulation"
] | [
"Actin-binding",
"Developmental protein"
] | [
"Cardiomyopathy",
"Disease variant"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Uncertain | Enhanced | null | 7 | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 55: Myocytes - Oxidative muscle function | Cluster 41: Striated muscle - Muscle contraction | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in single | null | Cancer enriched | Detected in some | 7 | Group enriched | Detected in some | 9 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,024 | 8 |
ENSG00000129173 | E2F8 | E2F transcription factor 8 | [
"A0AVK6"
] | 11 | 19224063-19241620 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064882",
"HPA076614"
] | [
"FLJ23311"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Cell cycle",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm",
"Nucleoli"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 17 | No | No | Cluster 9: T-regs - Cell cycle regulation | Cluster 48: Non-specific - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 63: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 2 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 6,025 | 7 |
ENSG00000129187 | DCTD | DCMP deaminase | [
"P32321"
] | 4 | 182890060-182917936 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035894"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Nucleotide biosynthesis"
] | [
"Allosteric enzyme",
"Hydrolase"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 13 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 22: Non-specific - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 97: Non-specific - Cellular respiration | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,026 | 2 |
ENSG00000129194 | SOX15 | SRY-box transcription factor 15 | [
"O60248"
] | 17 | 7588178-7590094 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA067196",
"HPA074049"
] | [
"SOX20",
"SOX26",
"SOX27"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Vesicles"
] | [] | [] | Approved | Enhanced | null | 26 | Yes | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 26: Keratinocytes - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Ovary Serous Cystadenocarcinoma"
] | 6,027 | 3 |
ENSG00000129195 | PIMREG | PICALM interacting mitotic regulator | [
"Q9BSJ6"
] | 17 | 6444441-6451469 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043783",
"HPA049934"
] | [
"CATS",
"FAM64A",
"FLJ10156",
"FLJ10491",
"RCS1"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 20 | Yes | Yes | Cluster 16: Non-specific - Cell proliferation | Cluster 2: Neurons - Nucleosome | Cluster 24: Non-specific - Unknown function | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in single | null | 4 | 2 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 6,028 | 4 |
ENSG00000129197 | RPAIN | RPA interacting protein | [
"Q86UA6"
] | 17 | 5419641-5432877 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023924",
"HPA031526"
] | [
"hRIP",
"MGC4189",
"RIP"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli fibrillar center"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 27: Non-specific - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Uterine Corpus Endometrial Carcinoma"
] | 6,029 | 3 |
ENSG00000129204 | USP6 | Ubiquitin specific peptidase 6 | [
"P35125"
] | 17 | 5116032-5175034 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046969"
] | [
"HRP1",
"Tre-2",
"TRE17",
"Tre2",
"TRESMCR"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Calmodulin-binding",
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Cancer-related genes",
"Proto-oncogene"
] | [
"Vesicles"
] | [] | [] | [] | Supported | null | null | 6 | null | null | null | Cluster 50: Non-specific - Nucleic acid binding | Cluster 1: Neuronal - Visual perception | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 25: Non-specific - Basic cellular processes | Group enriched | Detected in some | 6 | Not detected | Not detected | null | Cancer enriched | Detected in single | 8 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,030 | 3 |
ENSG00000129214 | SHBG | Sex hormone binding globulin | [
"P04278"
] | 17 | 7613946-7633382 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"ABP",
"MGC126834",
"MGC138391",
"TEBG"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"FDA approved drug targets",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Transport"
] | null | null | null | null | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 5 | Low cancer specificity | Detected in some | null | Cancer enriched | Detected in some | 16 | Group enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,031 | 9 |
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