ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000129219 | PLD2 | Phospholipase D2 | [
"O14939"
] | 17 | 4807152-4823434 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA013397"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Approved | null | 22 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 44: Non-specific - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 6,032 | 2 |
ENSG00000129221 | AIPL1 | Aryl hydrocarbon receptor interacting protein like 1 | [
"Q9NZN9"
] | 17 | 6393693-6435199 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026578"
] | [
"LCA4"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Sensory transduction",
"Vision"
] | [] | [
"Disease variant",
"Leber congenital amaurosis"
] | [
"Nuclear speckles"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 24 | null | null | null | Cluster 6: Non-specific - Immune response | Cluster 1: Neuronal - Visual perception | Cluster 79: Photoreceptor cells - Phototransduction | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in some | 215 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in single | 6 | Cell type enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,033 | 4 |
ENSG00000129226 | CD68 | CD68 molecule | [
"P34810"
] | 17 | 7579491-7582111 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000051",
"CAB000066",
"HPA048982",
"CAB072861",
"CAB072862"
] | [
"DKFZp686M18236",
"GP110",
"LAMP4",
"SCARD1"
] | [
"CD markers",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [] | [] | [] | Supported | Enhanced | null | 11 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 6,034 | 8 |
ENSG00000129235 | TXNDC17 | Thioredoxin domain containing 17 | [
"Q9BRA2"
] | 17 | 6640985-6644541 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA022931"
] | [
"MGC14353",
"TRP14",
"TXNL5"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Approved | null | 7 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 21: Non-specific - Metabolism | Cluster 42: Non-specific - Unknown function | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 6,035 | 6 |
ENSG00000129244 | ATP1B2 | ATPase Na+/K+ transporting subunit beta 2 | [
"P14415"
] | 17 | 7646627-7657770 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010698"
] | [
"AMOG"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Ion transport",
"Potassium transport",
"Sodium transport",
"Sodium/potassium transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Supported | null | 1 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in all | 9 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 15 | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 6,036 | 2 |
ENSG00000129245 | FXR2 | FMR1 autosomal homolog 2 | [
"P51116"
] | 17 | 7591230-7614897 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011205",
"HPA022997"
] | [
"FMR1L2"
] | [
"Predicted intracellular proteins"
] | [] | [
"RNA-binding"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 142 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 45: Non-specific - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 6,037 | 8 |
ENSG00000129250 | KIF1C | Kinesin family member 1C | [
"O43896"
] | 17 | 4997950-5028401 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024602",
"HPA045020"
] | [
"SAX2",
"SPAX2",
"SPG58"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Motor protein"
] | [
"Disease variant",
"Neurodegeneration"
] | [
"Nucleoplasm",
"Nucleoli",
"Principal piece"
] | [] | [] | [] | Approved | Approved | null | 30 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 13: Oligodendrocytes - Mixed function | Cluster 42: Non-specific - Unknown function | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 6,038 | 4 |
ENSG00000129255 | MPDU1 | Mannose-P-dolichol utilization defect 1 | [
"O75352"
] | 17 | 7583529-7592789 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014845"
] | [
"CDGIf",
"Lec35",
"PQLC5",
"SL15",
"SLC66A5"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Transport"
] | [] | [
"Congenital disorder of glycosylation",
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [
"Mitochondria"
] | [] | [] | Supported | Uncertain | null | 14 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 42: Non-specific - Unknown function | Cluster 65: Non-specific - Cell growth & division | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 6,039 | 4 |
ENSG00000129292 | PHF20L1 | PHD finger protein 20 like 1 | [
"A8MW92"
] | 8 | 132775358-132848807 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025060",
"HPA028417"
] | [
"CGI-72",
"FLJ13649",
"FLJ21615",
"MGC64923",
"TDRD20B"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | [] | Approved | Uncertain | null | 36 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 16: Non-specific - Transcription | Cluster 40: Non-specific - Unknown function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 6,040 | 7 |
ENSG00000129295 | DNAAF11 | Dynein axonemal assembly factor 11 | [
"Q86X45"
] | 8 | 132570416-132675592 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028043",
"HPA028058"
] | [
"CILD19",
"LRRC6",
"LRTP",
"tilB",
"TSLRP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Ciliopathy",
"Disease variant",
"Kartagener syndrome",
"Primary ciliary dyskinesia"
] | [
"Mid piece",
"Principal piece"
] | [] | [] | [] | Approved | Approved | null | 9 | null | null | Cluster 20: Non-specific - DNA binding | Cluster 17: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma"
] | [
"Thyroid Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Thyroid Carcinoma"
] | 6,041 | 6 |
ENSG00000129317 | PUS7L | Pseudouridine synthase 7 like | [
"Q9H0K6"
] | 12 | 43718992-43758793 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056203",
"HPA058750"
] | [
"DKFZP434G1415"
] | [
"Predicted intracellular proteins"
] | [
"mRNA processing"
] | [
"Isomerase"
] | [] | [
"Nuclear speckles"
] | [
"Nucleoli"
] | [] | [] | Approved | Uncertain | null | 3 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 9: Non-specific - Receptor signaling | Cluster 38: Non-specific - Transcription | Cluster 109: Neurons - Neuronal signaling | Cluster 42: Retina - Visual perception | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 6,043 | 6 |
ENSG00000129347 | KRI1 | KRI1 homolog | [
"Q8N9T8"
] | 19 | 10553085-10566031 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043110",
"HPA043574"
] | [
"FLJ12949"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Enhanced | Approved | null | 22 | Yes | No | Cluster 30: Non-specific - DNA binding | Cluster 6: Non-specific - Immune response | Cluster 23: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 6,044 | 7 |
ENSG00000129351 | ILF3 | Interleukin enhancer binding factor 3 | [
"Q12906"
] | 19 | 10654304-10692400 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001897"
] | [
"DRBP76",
"MPHOSPH4",
"MPP4",
"MPP4110",
"NF110",
"NF110b",
"NF90",
"NF90a",
"NF90c",
"NF90ctv",
"NFAR-1",
"NFAR-2",
"NFAR110",
"NFAR90",
"TCP110"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"RNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Nucleoli",
"Mitochondria"
] | [] | [] | [] | Enhanced | Supported | null | 422 | No | No | Cluster 12: Non-specific - Mitochondrial translation | Cluster 55: Non-specific - Transcription | Cluster 23: Non-specific - Transcription | Cluster 17: Non-specific - RNA processing | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,045 | 3 |
ENSG00000129353 | SLC44A2 | Solute carrier family 44 member 2 | [
"Q8IWA5"
] | 19 | 10602457-10644557 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003228",
"HPA070799"
] | [
"CTL2"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Transport"
] | [] | [] | [
"Vesicles",
"Cell Junctions"
] | [] | [] | [] | Approved | Approved | null | 5 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 39: Astrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 6,046 | 4 |
ENSG00000129354 | AP1M2 | Adaptor related protein complex 1 subunit mu 2 | [
"Q9Y6Q5"
] | 19 | 10572671-10587315 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054999",
"HPA077258"
] | [
"AP1-mu2",
"HSMU1B",
"mu2"
] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 23 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 51: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 60: Stomach - Digestion | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 2 | 1 | [] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 6,047 | 1 |
ENSG00000129355 | CDKN2D | Cyclin dependent kinase inhibitor 2D | [
"P55273"
] | 19 | 10566460-10569059 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011201",
"HPA043546"
] | [
"INK4D",
"p19"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [] | [
"Tumor suppressor"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 49 | null | Yes | Cluster 22: Eosinophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 59: Leukemia - T-cell receptor | Cluster 47: Platelets - Hemostasis | Cluster 78: Brain - Neuronal signaling | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 6,048 | 3 |
ENSG00000129437 | KLK14 | Kallikrein related peptidase 14 | [
"Q9P0G3"
] | 19 | 51077495-51084245 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB026228"
] | [
"KLK-L6"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Cancer-related genes"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | null | Uncertain | null | null | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 37: Skin - Keratinization | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 6,050 | 8 |
ENSG00000129450 | SIGLEC9 | Sialic acid binding Ig like lectin 9 | [
"Q9Y336"
] | 19 | 51124906-51136651 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA010682",
"CAB080397"
] | [
"CD329"
] | [
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 4 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 51: Myeloma - Immunoglobulins | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 7 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in many | 10 | 0 | 0 | 0 | [] | [] | [] | 6,051 | 6 |
ENSG00000129451 | KLK10 | Kallikrein related peptidase 10 | [
"O43240"
] | 19 | 51012739-51020175 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"NES1",
"PRSSL1"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted secreted proteins"
] | [
"Cell cycle"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Cancer-related genes",
"Tumor suppressor"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | null | null | null | 115 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 81: Squamous epithelium - Keratinization | Group enriched | Detected in many | 4 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Breast Invasive Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Pancreatic Adenocarcinoma"
] | 6,052 | 5 |
ENSG00000129455 | KLK8 | Kallikrein related peptidase 8 | [
"O60259"
] | 19 | 50996007-51002711 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB019393",
"HPA035761"
] | [
"HNP",
"neuropsin",
"ovasin",
"PRSS19",
"TADG14"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [
"Cancer-related genes"
] | [
"Vesicles"
] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | Approved | Enhanced | null | 15 | null | null | null | Cluster 25: Non-specific - Transcription | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 26: Keratinocytes - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Bladder Urothelial Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Pancreatic Adenocarcinoma"
] | 6,053 | 9 |
ENSG00000129460 | NGDN | Neuroguidin | [
"Q8NEJ9"
] | 14 | 23469679-23509862 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000944"
] | [
"C14orf120",
"CANu1",
"DKFZP564O092",
"LCP5",
"lpd-2",
"NGD"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Translation regulation"
] | [
"Repressor"
] | [] | [
"Nucleoli",
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 12 | Yes | No | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 17: Non-specific - RNA processing | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,054 | 1 |
ENSG00000129465 | RIPK3 | Receptor interacting serine/threonine kinase 3 | [
"Q9Y572"
] | 14 | 24336025-24340022 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"RIP3"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Transporters"
] | [
"Apoptosis",
"Host-virus interaction",
"Necrosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [] | [] | [] | [] | null | null | null | 24 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 15: Non-specific - Protein processing | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 6,055 | 2 |
ENSG00000129467 | ADCY4 | Adenylate cyclase 4 | [
"Q8NFM4"
] | 14 | 24318349-24335093 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB005070",
"HPA048344"
] | [
"AC4"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"cAMP biosynthesis"
] | [
"Lyase"
] | [] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [] | Approved | Approved | null | 3 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Not detected | Not detected | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 9 | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,056 | 6 |
ENSG00000129472 | RAB2B | RAB2B, member RAS oncogene family | [
"Q8WUD1"
] | 14 | 21459020-21476960 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050292"
] | [
"FLJ14824"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 31 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 45: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 6,057 | 2 |
ENSG00000129473 | BCL2L2 | BCL2 like 2 | [
"Q92843"
] | 14 | 23298790-23311751 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB040539",
"HPA048740"
] | [
"BCL-W",
"KIAA0271",
"PPP1R51"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Apoptosis"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Uncertain | Approved | null | 64 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,058 | 3 |
ENSG00000129474 | AJUBA | Ajuba LIM protein | [
"Q96IF1"
] | 14 | 22971177-22982551 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006171"
] | [
"JUB",
"MGC15563"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Cell adhesion",
"Cell cycle",
"RNA-mediated gene silencing",
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Golgi apparatus"
] | [] | [] | [] | Approved | Approved | null | 41 | null | Yes | null | Cluster 3: Choroid plexus - Cilium | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 22: Non-specific - Basic cellular functions | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,059 | 1 |
ENSG00000129480 | DTD2 | D-aminoacyl-tRNA deacylase 2 | [
"Q96FN9"
] | 14 | 31446036-31457506 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA001117"
] | [
"C14orf126",
"MGC9912"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"RNA-binding",
"tRNA-binding"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 24: Non-specific - Transcription | Cluster 11: White matter - Signal transduction | Cluster 30: Non-specific - Gene expression regulation | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 36: Brain & Liver - Signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 6,060 | 4 |
ENSG00000129484 | PARP2 | Poly(ADP-ribose) polymerase 2 | [
"Q9UGN5"
] | 14 | 20343615-20357904 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018137",
"HPA052003"
] | [
"ADPRTL2",
"ARTD2"
] | [
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [
"Allosteric enzyme",
"DNA-binding",
"Glycosyltransferase",
"Nucleotidyltransferase",
"Transferase"
] | [
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Supported | Approved | null | 20 | null | Yes | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 27: Non-specific - Cell proliferation | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 2 | 1 | [] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | 6,061 | 2 |
ENSG00000129493 | HEATR5A | HEAT repeat containing 5A | [
"Q86XA9"
] | 14 | 31291788-31420550 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA049539"
] | [
"C14orf125",
"DKFZP434I1735",
"p200b"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | Cluster 41: Basophils - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 30: Non-specific - Gene expression regulation | Cluster 7: Non-specific - Transcription | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 6,062 | 2 |
ENSG00000129514 | FOXA1 | Forkhead box A1 | [
"P55317"
] | 14 | 37589552-37596059 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB011595",
"HPA050505"
] | [
"HNF3A"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator",
"Developmental protein",
"DNA-binding",
"Repressor"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Supported | Enhanced | null | 36 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Group enriched | Detected in many | 5 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 6,063 | 5 |
ENSG00000129515 | SNX6 | Sorting nexin 6 | [
"Q9UNH7"
] | 14 | 34561093-34630160 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049374"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Endosomes",
"Lysosomes"
] | [] | [] | [] | Supported | Approved | null | 43 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 11: White matter - Signal transduction | Cluster 30: Non-specific - Gene expression regulation | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,064 | 5 |
ENSG00000129518 | EAPP | E2F associated phosphoprotein | [
"Q56P03"
] | 14 | 34515938-34539704 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002916",
"HPA071031"
] | [
"BM036",
"C14orf11",
"FLJ20578"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear speckles"
] | [] | [] | Supported | Approved | null | 49 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 31: Non-specific - Transcription | Cluster 30: Non-specific - Gene expression regulation | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,065 | 7 |
ENSG00000129521 | EGLN3 | Egl-9 family hypoxia inducible factor 3 | [
"Q9H6Z9"
] | 14 | 33924227-34462774 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064895"
] | [
"HIFPH3",
"PHD3"
] | [
"Enzymes",
"FDA approved drug targets",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"DNA damage"
] | [
"Dioxygenase",
"Oxidoreductase"
] | [
"FDA approved drug targets"
] | [
"Cytosol"
] | [] | [] | [] | Supported | null | null | 56 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cancer enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in some | 10 | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 6,066 | 6 |
ENSG00000129534 | MIS18BP1 | MIS18 binding protein 1 | [
"Q6P0N0"
] | 14 | 45203190-45253540 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006504"
] | [
"C14orf106",
"FLJ11186",
"KIAA1903",
"KNL2",
"M18BP1"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"DNA-binding"
] | [] | [
"Nucleoli"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 16 | null | Yes | Cluster 41: Basophils - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 30: Non-specific - Gene expression regulation | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,067 | 6 |
ENSG00000129535 | NRL | Neural retina leucine zipper | [
"P54845"
] | 14 | 24078662-24115010 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB026066",
"HPA064599"
] | [
"D14S46E",
"NRL-MAF",
"RP27"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Sensory transduction",
"Transcription",
"Transcription regulation",
"Vision"
] | [
"Activator",
"Developmental protein",
"DNA-binding"
] | [
"Disease variant",
"Retinitis pigmentosa"
] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 2 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 43: Hindbrain - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 42: Retina - Visual perception | Tissue enriched | Detected in many | 73 | Cancer enriched | Detected in some | 4 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 6,068 | 7 |
ENSG00000129538 | RNASE1 | Ribonuclease A family member 1, pancreatic | [
"P07998"
] | 14 | 20801228-20802855 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001140"
] | [
"RAC1",
"RNS1"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Endonuclease",
"Hydrolase",
"Lyase",
"Nuclease"
] | [] | [
"Vesicles"
] | [
"Nucleoplasm"
] | [
"Secreted to digestive system"
] | [
"Enzyme"
] | Approved | Enhanced | null | 5 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 69: Skin cancer - ECM organization | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 8: Pancreas - Proteolysis | Tissue enriched | Detected in all | 9 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 6,069 | 8 |
ENSG00000129559 | NEDD8 | NEDD8 ubiquitin like modifier | [
"Q15843"
] | 14 | 24216857-24232367 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004082",
"HPA027583",
"HPA060254"
] | [
"Nedd-8"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [
"Golgi apparatus",
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 100 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 30: Non-specific - Gene expression regulation | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,070 | 4 |
ENSG00000129562 | DAD1 | Defender against cell death 1 | [
"P61803"
] | 14 | 22564907-22589224 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028882"
] | [
"OST2"
] | [
"Cancer-related genes",
"Essential proteins",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Apoptosis"
] | [] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Endoplasmic reticulum"
] | [] | [] | Uncertain | Uncertain | null | 57 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 35: RS4;11 - Unknown function | Cluster 8: Non-specific - Secretory pathway | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 4 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 6,071 | 7 |
ENSG00000129566 | TEP1 | Telomerase associated protein 1 | [
"Q99973"
] | 14 | 20365667-20413501 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA029206"
] | [
"p240",
"TLP1",
"TP1",
"TROVE1",
"VAULT2"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Approved | null | null | 7 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 20: Macrophages & Microglia - Immune response | Cluster 30: Non-specific - Gene expression regulation | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 6,072 | 9 |
ENSG00000129595 | EPB41L4A | Erythrocyte membrane protein band 4.1 like 4A | [
"Q9HCS5"
] | 5 | 112142441-112419313 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036580"
] | [
"NBL4"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 32: Basophils - Transcription | Cluster 42: Choroid plexus - Mitochondria | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 22: Epididymis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 6,073 | 8 |
ENSG00000129596 | CDO1 | Cysteine dioxygenase type 1 | [
"Q16878"
] | 5 | 115804733-115816659 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036573",
"HPA057503"
] | [] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Dioxygenase",
"Oxidoreductase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Uncertain | Enhanced | null | null | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in single | null | 2 | 2 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | 6,074 | 4 |
ENSG00000129625 | REEP5 | Receptor accessory protein 5 | [
"Q00765"
] | 5 | 112876385-112922289 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003895",
"HPA069960"
] | [
"C5orf18",
"D5S346",
"DP1",
"POB16",
"TB2",
"Yip2e"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Approved | null | 106 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 27: Breast cancer - Unknown function | Cluster 8: Non-specific - Secretory pathway | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 6,075 | 9 |
ENSG00000129636 | ITFG1 | Integrin alpha FG-GAP repeat containing 1 | [
"Q8TB96"
] | 16 | 47154387-47464149 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA015590",
"HPA019728",
"HPA019752"
] | [
"CDA08",
"LNKN-1",
"TIP"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus",
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Approved | Approved | null | 37 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 23: Choroid plexus - Mixed function | Cluster 68: Non-specific - Cell cycle regulation | Cluster 43: Sertoli cells - Spermatogenesis microenvironment | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,076 | 5 |
ENSG00000129646 | QRICH2 | Glutamine rich 2 | [
"Q9H0J4"
] | 17 | 76274049-76308276 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052219"
] | [
"DKFZP434P0316"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Nucleoplasm",
"Nuclear membrane"
] | [
"Vesicles"
] | [] | [] | Uncertain | Enhanced | null | null | null | null | null | Cluster 37: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 109: Neurons - Neuronal signaling | Cluster 67: Testis - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | 6,077 | 2 |
ENSG00000129654 | FOXJ1 | Forkhead box J1 | [
"Q92949"
] | 17 | 76136333-76141245 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005714"
] | [
"FKHL13",
"HFH-4",
"HFH4"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Cilium biogenesis/degradation",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes",
"Ciliopathy",
"Disease variant",
"Primary ciliary dyskinesia"
] | [] | [] | [] | [] | null | Enhanced | null | 22 | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 10: Ciliated cells - Ion channel activity | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 2 | 2 | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 6,078 | 4 |
ENSG00000129657 | SEC14L1 | SEC14 like lipid binding 1 | [
"Q92503"
] | 17 | 77088749-77217101 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021463",
"HPA028703"
] | [
"PRELID4A",
"SEC14L"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Immunity",
"Innate immunity"
] | [
"Signal transduction inhibitor"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 4 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 25: Non-specific - Transcription | Cluster 48: Adipocytes & Endothelial cells - Angiogenesis | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in all | 7 | 3 | 2 | 2 | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Prostate Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Prostate Adenocarcinoma"
] | 6,079 | 7 |
ENSG00000129667 | RHBDF2 | Rhomboid 5 homolog 2 | [
"Q6PJF5"
] | 17 | 76470891-76501790 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA018080"
] | [
"FLJ22341",
"iRhom2",
"RHBDL5",
"RHBDL6",
"TOC",
"TOCG"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Protein transport",
"Transport"
] | [
"Growth factor binding"
] | [
"Disease variant",
"Palmoplantar keratoderma"
] | [] | [] | [] | [] | null | Uncertain | null | 4 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 66: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 6,080 | 5 |
ENSG00000129673 | AANAT | Aralkylamine N-acetyltransferase | [
"Q16613"
] | 17 | 76453351-76470117 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054321"
] | [
"SNAT"
] | [
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"Melatonin biosynthesis"
] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | null | null | 7 | null | null | null | Cluster 20: Macrophages & Microglia - Immune response | Cluster 1: Neuronal - Visual perception | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 46: Brain & retina - Neuronal signaling | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in single | null | Group enriched | Detected in some | 6 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,081 | 3 |
ENSG00000129675 | ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor 6 | [
"Q15052"
] | X | 136665547-136780932 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003578",
"HPA071036"
] | [
"alpha-PIX",
"alphaPIX",
"Cool-2",
"Cool2",
"KIAA0006",
"MRX46"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [
"Cancer-related genes"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 38 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 19: Astrocytes - Mixed function | Cluster 49: HMC-1 - Innate immune response | Cluster 58: Mast cells - Allergic inflammatory responses | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 6,082 | 9 |
ENSG00000129680 | MAP7D3 | MAP7 domain containing 3 | [
"Q8IWC1"
] | X | 136213220-136256482 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA035598",
"HPA058101"
] | [
"FLJ12649"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Centrosome"
] | [
"Nucleoplasm",
"Primary cilium",
"Basal body"
] | [] | [] | Uncertain | Approved | null | 16 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 36: Non-specific - mRNA processing | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,083 | 7 |
ENSG00000129682 | FGF13 | Fibroblast growth factor 13 | [
"Q92913"
] | X | 138614727-139222777 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002809"
] | [
"FGF2",
"FHF2",
"FLJ30672",
"LINC00889"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Neurogenesis"
] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Cytosol"
] | [] | [] | [] | Supported | null | null | 5 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 29: Forebrain - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 25: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 6,084 | 6 |
ENSG00000129691 | ASH2L | ASH2 like, histone lysine methyltransferase complex subunit | [
"Q9UBL3"
] | 8 | 38105493-38144076 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042289"
] | [
"ASH2",
"ASH2L1",
"ASH2L2",
"Bre2"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane"
] | [] | [] | Supported | Approved | null | 84 | Yes | No | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 14: Neurons - Synaptic function | Cluster 40: Non-specific - Unknown function | Cluster 94: Gonadal somatic cells - Mixed function | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 6,085 | 2 |
ENSG00000129696 | TTI2 | TELO2 interacting protein 2 | [
"Q6NXR4"
] | 8 | 33473386-33513185 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023523",
"HPA029823"
] | [
"C8orf41",
"FLJ23263"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Centrosome"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 12 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 40: Non-specific - Unknown function | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,086 | 5 |
ENSG00000129744 | ART1 | ADP-ribosyltransferase 1 | [
"P52961"
] | 11 | 3645128-3664416 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA051148"
] | [
"ART2",
"ARTC1",
"CD296"
] | [
"CD markers",
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Glycosyltransferase",
"Nucleotidyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 70: DU4475 - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 56 | Not detected | Not detected | null | Not detected | Not detected | null | Group enriched | Detected in some | 16 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,087 | 3 |
ENSG00000129749 | CHRNA10 | Cholinergic receptor nicotinic alpha 10 subunit | [
"Q9GZZ6"
] | 11 | 3665587-3671384 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"FDA approved drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel",
"Ligand-gated ion channel",
"Receptor"
] | [
"FDA approved drug targets"
] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 70: DU4475 - Unknown function | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enriched | Detected in some | 21 | Low cancer specificity | Detected in single | null | Low cancer specificity | Detected in single | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,088 | 2 |
ENSG00000129757 | CDKN1C | Cyclin dependent kinase inhibitor 1C | [
"P49918"
] | 11 | 2883213-2885775 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA002924"
] | [
"BWCR",
"BWS",
"KIP2",
"P57"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle"
] | [
"Protein kinase inhibitor"
] | [
"Cancer-related genes",
"Disease variant",
"Tumor suppressor"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 19 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 30: White matter - Myelination | Cluster 70: DU4475 - Unknown function | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 74: Non-specific - Signal transduction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 9 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,089 | 4 |
ENSG00000129810 | SGO1 | Shugoshin 1 | [
"Q5FBB7"
] | 3 | 20160593-20186206 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035501",
"HPA069302",
"HPA069857"
] | [
"NY-BR-85",
"SGOL1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Chromosome partition",
"Mitosis"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Kinetochore",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 26 | Yes | Yes | Cluster 17: B-cells - Immunoglobulins | Cluster 6: Non-specific - Immune response | Cluster 8: Non-specific - Basic cellular processes | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 6,090 | 6 |
ENSG00000129824 | RPS4Y1 | Ribosomal protein S4 Y-linked 1 | [
"P22090"
] | Y | 2841602-2932000 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000857"
] | [
"MGC119100",
"MGC5070",
"RPS4Y",
"S4"
] | [
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein",
"RNA-binding",
"rRNA-binding"
] | [] | [] | [] | [] | [] | null | Approved | null | 31 | null | null | Cluster 43: Non-specific - Transcription & Translation | Cluster 21: Non-specific - Metabolism | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 6,091 | 5 |
ENSG00000129862 | VCY1B | Variable charge Y-linked 1B | [
"O14598"
] | Y | 14056227-14056958 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044996",
"HPA049357"
] | [
"BPY1B"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Supported | null | 1 | null | null | null | null | Cluster 69: Skin cancer - ECM organization | null | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in single | 144 | Group enriched | Detected in many | 7 | Cancer enriched | Detected in some | 8 | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,092 | 7 |
ENSG00000129864 | VCY | Variable charge Y-linked | [
"O14598"
] | Y | 13985772-13986473 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044996",
"HPA049357"
] | [
"BPY1",
"VCY1",
"VCY1A"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Supported | null | 1 | null | null | null | null | Cluster 69: Skin cancer - ECM organization | null | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in single | 607 | Cancer enriched | Detected in some | 8 | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,093 | 8 |
ENSG00000129873 | CDY2B | Chromodomain Y-linked 2B | [
"Q9Y6F7"
] | Y | 17878260-17880220 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA066682"
] | [
"CDY"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Supported | null | null | null | null | null | null | null | null | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected | Not detected | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,094 | 9 |
ENSG00000129910 | CDH15 | Cadherin 15 | [
"P55291"
] | 16 | 89171748-89195492 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009139",
"HPA070961"
] | [
"CDH14",
"CDH3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted membrane proteins"
] | [
"Cell adhesion"
] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Golgi apparatus",
"Plasma membrane"
] | [] | [] | [] | Supported | Enhanced | Supported | 5 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 33: Sarcoma - Muscle contraction | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in some | 13 | Cancer enriched | Detected in some | 18 | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,095 | 3 |
ENSG00000129911 | KLF16 | KLF transcription factor 16 | [
"Q9BXK1"
] | 19 | 1852399-1863579 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA052481"
] | [
"BTEB4",
"DRRF",
"NSLP2"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Approved | null | 18 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | 6,096 | 6 |
ENSG00000129925 | PGAP6 | Post-GPI attachment to proteins 6 | [
"Q9HCN3"
] | 16 | 370788-387113 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051281",
"HPA064673"
] | [
"M83",
"TMEM6",
"TMEM8",
"TMEM8A"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Lipid metabolism"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Cytokinetic bridge"
] | [] | [] | Supported | Approved | null | 10 | Yes | No | Cluster 4: Neutrophils - Degranulation | Cluster 12: Non-specific - Vasculature | Cluster 54: Non-specific - Transcription | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 8: Pancreas - Proteolysis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 6,097 | 5 |
ENSG00000129932 | DOHH | Deoxyhypusine hydroxylase | [
"Q9BU89"
] | 19 | 3490821-3500674 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA041953",
"HPA076271"
] | [
"HLRC1",
"MGC4293"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Hypusine biosynthesis"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Cytosol"
] | [
"Nucleoplasm",
"Nucleoli"
] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 11: White matter - Signal transduction | Cluster 23: Non-specific - Transcription | Cluster 97: Non-specific - Cellular respiration | Cluster 68: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 6,098 | 5 |
ENSG00000129933 | MAU2 | MAU2 sister chromatid cohesion factor | [
"Q9Y6X3"
] | 19 | 19320829-19358754 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059897"
] | [
"KIAA0892",
"mau-2",
"MAU2L",
"MGC75361",
"SCC4"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Chromosome partition",
"Mitosis"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | null | null | 20 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 6: Non-specific - Immune response | Cluster 23: Non-specific - Transcription | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 6,099 | 2 |
ENSG00000129946 | SHC2 | SHC adaptor protein 2 | [
"P98077"
] | 19 | 416589-461033 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006136"
] | [
"SCK",
"SHCB",
"SLI"
] | [
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 21 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 70: Non-specific - Protein processing | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,100 | 5 |
ENSG00000129951 | PLPPR3 | Phospholipid phosphatase related 3 | [
"Q6T4P5"
] | 19 | 812488-821955 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA052293",
"HPA057034"
] | [
"FLJ11535",
"LPPR3",
"PRG-2",
"PRG2"
] | [
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 78: Brain - Neuronal signaling | Tissue enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,101 | 4 |
ENSG00000129965 | INS-IGF2 | INS-IGF2 readthrough | [
"F8WCM5"
] | 11 | 2132538-2161209 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB019430",
"HPA071234"
] | [] | [
"Predicted secreted proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [
"Secreted to digestive system"
] | [
"No annotated function"
] | Uncertain | Enhanced | null | null | null | null | null | null | Cluster 33: Sarcoma - Muscle contraction | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 8: Pancreas - Proteolysis | Group enriched | Detected in some | 5 | Group enriched | Detected in some | 4 | Cancer enriched | Detected in single | 52 | Cell type enriched | Detected in some | 30 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,102 | 9 |
ENSG00000129968 | ABHD17A | Abhydrolase domain containing 17A, depalmitoylase | [
"Q96GS6"
] | 19 | 1876810-1885496 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043270",
"HPA047226",
"HPA069225"
] | [
"C19orf27",
"FAM108A1",
"MGC5244"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Hydrolase"
] | [] | [
"Vesicles"
] | [
"Nuclear speckles"
] | [] | [] | Approved | Uncertain | null | 1 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 23: Non-specific - Transcription | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 68: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 6,103 | 4 |
ENSG00000129988 | LBP | Lipopolysaccharide binding protein | [
"P18428"
] | 20 | 38346482-38377013 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001508",
"CAB025905"
] | [
"BPIFD2"
] | [
"Plasma proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Immunity",
"Innate immunity",
"Lipid transport",
"Transport"
] | [
"Antibiotic",
"Antimicrobial"
] | [] | [] | [] | [
"Secreted to blood"
] | [
"Transport"
] | null | Approved | null | 2 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 71: Lymphoma - Inflammatory response | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 24 | Group enriched | Detected in some | 8 | Cancer enriched | Detected in many | 11 | Cell type enriched | Detected in some | 19 | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 6,104 | 5 |
ENSG00000129990 | SYT5 | Synaptotagmin 5 | [
"O00445"
] | 19 | 55171196-55180289 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA078390"
] | [] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 5: Rhabdoid - Unknown function | Cluster 76: Pancreatic endocrine cells - Endocrine signaling | Cluster 78: Brain - Neuronal signaling | Group enriched | Detected in some | 9 | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 6,105 | 1 |
ENSG00000129991 | TNNI3 | Troponin I3, cardiac type | [
"P19429"
] | 19 | 55151767-55157773 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009349",
"HPA046428"
] | [
"CMD2A",
"CMH7",
"TNNC1"
] | [
"Candidate cardiovascular disease genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Muscle protein"
] | [
"Cardiomyopathy",
"Disease variant"
] | [
"Cytosol"
] | [
"Vesicles"
] | [] | [] | Approved | Enhanced | null | 18 | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 12: Bone cancer - Neuronal signaling | Cluster 108: Fibroblasts - ECM organization | Cluster 35: Non-specific - Mixed function | Tissue enriched | Detected in many | 158 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 5 | Group enriched | Detected in some | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,106 | 1 |
ENSG00000129993 | CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3 | [
"O75081"
] | 16 | 88874858-88977207 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059931",
"HPA062423",
"HPA065890"
] | [
"ETO2",
"MTG16",
"MTGR2",
"RUNX1T3",
"ZMYND4"
] | [
"Cancer-related genes",
"Disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 21 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 15: Non-specific - Transcription | Cluster 47: Leukemia - Hemostasis | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 3 | 0 | 3 | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 6,107 | 4 |
ENSG00000130005 | GAMT | Guanidinoacetate N-methyltransferase | [
"Q14353"
] | 19 | 1397026-1401570 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051806"
] | [
"PIG2",
"TP53I2"
] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Transferase"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Approved | null | 8 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 11: White matter - Signal transduction | Cluster 35: RS4;11 - Unknown function | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 19: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 6,108 | 2 |
ENSG00000130021 | PUDP | Pseudouridine 5'-phosphatase | [
"Q08623"
] | X | 6667865-7148158 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA000292",
"HPA072672"
] | [
"DXF68S1E",
"FAM16AX",
"GS1",
"HDHD1",
"HDHD1A"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Nucleotide metabolism"
] | [
"Hydrolase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 27 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 21: Non-specific - Metabolism | Cluster 36: Non-specific - mRNA processing | Cluster 7: Non-specific - Transcription | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 6,109 | 8 |
ENSG00000130023 | ERMARD | ER membrane associated RNA degradation | [
"Q5T6L9"
] | 6 | 169751622-169781600 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041741"
] | [
"C6orf70",
"dJ266L20.3",
"FLJ11152"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Developmental protein"
] | [
"Disease variant"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | null | null | null | Cluster 33: Non-specific - ATP binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 41: Oocytes - Oogenesis | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 6,110 | 7 |
ENSG00000130024 | PHF10 | PHD finger protein 10 | [
"Q8WUB8"
] | 6 | 169703902-169725566 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055649"
] | [
"BAF45a",
"FLJ10975",
"SMARCG4",
"XAP135"
] | [
"Predicted intracellular proteins"
] | [
"Neurogenesis",
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Supported | null | 52 | null | null | Cluster 24: Non-specific - Transcription | Cluster 19: Astrocytes - Mixed function | Cluster 28: Non-specific - Nuclear processes | Cluster 103: Non-specific - Basic cellular processes | Cluster 4: Adrenal gland - Steroid metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 6,111 | 8 |
ENSG00000130035 | GALNT8 | Polypeptide N-acetylgalactosaminyltransferase 8 | [
"Q9NY28"
] | 12 | 4720400-4851927 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA012638",
"HPA073461"
] | [
"GALNAC-T8"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [] | [
"Golgi apparatus"
] | [
"Vesicles"
] | [] | [] | Approved | Supported | null | 1 | null | No | null | Cluster 11: White matter - Signal transduction | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,113 | 6 |
ENSG00000130037 | KCNA5 | Potassium voltage-gated channel subfamily A member 5 | [
"P22460"
] | 12 | 5043879-5046788 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA021516",
"CAB022562"
] | [
"HK2",
"HPCN1",
"Kv1.5"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Ion channel",
"Potassium channel",
"Voltage-gated channel"
] | [
"Atrial fibrillation",
"FDA approved drug targets"
] | [] | [] | [] | [] | null | Approved | null | 14 | null | null | Cluster 44: Plasmacytoid DCs - Plasma membrane proteins | Cluster 36: Choroid plexus - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 1: Choroid plexus - Transmembrane transport | Group enriched | Detected in many | 6 | Cancer enriched | Detected in single | 6 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in single | 122 | 0 | 0 | 0 | [] | [] | [] | 6,114 | 7 |
ENSG00000130038 | CRACR2A | Calcium release activated channel regulator 2A | [
"Q9BSW2"
] | 12 | 3606633-3764819 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038686"
] | [
"EFCAB4B",
"MGC4266",
"RAB46"
] | [
"Predicted intracellular proteins"
] | [
"Adaptive immunity",
"Calcium transport",
"Immunity",
"Ion transport",
"Transport"
] | [
"Hydrolase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 34 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 8: Immune cells - Immune response | Cluster 72: Neuronal - Signal transduction | Cluster 70: Intestinal goblet cells - Mucin production | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 6,115 | 7 |
ENSG00000130045 | NXNL2 | Nucleoredoxin like 2 | [
"Q5VZ03"
] | 9 | 88534033-88584274 | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | Evidence at transcript level | [
"HPA045526"
] | [
"C9orf121",
"RdCVF2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 41: Basophils - Unknown function | Cluster 9: Non-specific - Receptor signaling | Cluster 15: Kidney cancer - Membrane components | Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion | Cluster 48: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,116 | 6 |
ENSG00000130052 | STARD8 | StAR related lipid transfer domain containing 8 | [
"Q92502"
] | X | 68647666-68725842 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA060788"
] | [
"ARHGAP38",
"KIAA0189"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [] | [] | [] | [] | null | Uncertain | null | 1 | null | Yes | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 47: Endothelial cells - Vasculature | Cluster 47: Leukemia - Hemostasis | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 15 | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Stomach Adenocarcinoma"
] | 6,117 | 1 |
ENSG00000130054 | NALF2 | NALCN channel auxiliary factor 2 | [
"O75949"
] | X | 69504326-69532508 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA036093"
] | [
"CXorf63",
"FAM155B",
"TED",
"TMEM28"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 1: Neuronal - Visual perception | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 35: Non-specific - Mixed function | Tissue enriched | Detected in some | 5 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 6,118 | 7 |
ENSG00000130055 | GDPD2 | Glycerophosphodiester phosphodiesterase domain containing 2 | [
"Q9HCC8"
] | X | 70423031-70433390 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"FLJ20207",
"GDE3",
"OBDPF"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Hydrolase"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 46: Brainstem - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 6,119 | 8 |
ENSG00000130066 | SAT1 | Spermidine/spermine N1-acetyltransferase 1 | [
"P21673"
] | X | 23783173-23786210 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB047343",
"HPA055312",
"CAB069914"
] | [
"SAT",
"SSAT"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Supported | null | 49 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 4 | 0 | 0 | 0 | [] | [] | [] | 6,120 | 7 |
ENSG00000130119 | GNL3L | G protein nucleolar 3 like | [
"Q9NVN8"
] | X | 54530183-54621521 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036314",
"HPA036315"
] | [
"FLJ10613",
"GNL3B"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis"
] | [] | [] | [
"Nucleoli"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Supported | null | 22 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 28: Oligodendrocytes - Mixed function | Cluster 36: Non-specific - mRNA processing | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,121 | 4 |
ENSG00000130147 | SH3BP4 | SH3 domain binding protein 4 | [
"Q9P0V3"
] | 2 | 234952017-235055714 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA037533",
"HPA037534"
] | [] | [
"Predicted intracellular proteins"
] | [
"Endocytosis"
] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 46 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 72: Neuronal - Signal transduction | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 14 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,122 | 7 |
ENSG00000130158 | DOCK6 | Dedicator of cytokinesis 6 | [
"Q96HP0"
] | 19 | 11199295-11262524 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049423",
"HPA049424"
] | [
"KIAA1395",
"ZIR1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 15 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,124 | 5 |
ENSG00000130164 | LDLR | Low density lipoprotein receptor | [
"P01130"
] | 19 | 11089462-11133820 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009647",
"HPA009974",
"HPA013159"
] | [
"LDLCQ2"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cholesterol metabolism",
"Endocytosis",
"Host-virus interaction",
"Lipid metabolism",
"Lipid transport",
"Steroid metabolism",
"Sterol metabolism",
"Transport"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [
"Disease variant"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Approved | null | 31 | null | null | Cluster 41: Basophils - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 28: Liver & Adrenal gland - Secretion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 9 | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 6,126 | 8 |
ENSG00000130165 | ELOF1 | Elongation factor 1 | [
"P60002"
] | 19 | 11551147-11559230 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045606"
] | [
"ELF1",
"MGC4549"
] | [
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 2 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 31: Non-specific - Transcription | Cluster 23: Non-specific - Transcription | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 56: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 6,127 | 9 |
ENSG00000130167 | TSPAN16 | Tetraspanin 16 | [
"Q9UKR8"
] | 19 | 11296139-11326996 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA076551"
] | [
"TM-8",
"TM4-B",
"TM4SF16"
] | [
"Predicted membrane proteins"
] | [] | [] | [] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Enhanced | null | 2 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 56: Late spermatids - Spermiogenesis: Maturation | Cluster 23: Testis - Spermatogenesis | Tissue enriched | Detected in some | 26 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in many | 7 | Group enriched | Detected in some | 11 | 0 | 0 | 0 | [] | [] | [] | 6,128 | 1 |
ENSG00000130173 | ANGPTL8 | Angiopoietin like 8 | [
"Q6UXH0"
] | 19 | 11237450-11241943 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA042131"
] | [
"C19orf80",
"RIFL",
"TD26"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Lipid metabolism"
] | [
"Hormone"
] | [
"Diabetes mellitus"
] | [
"Golgi apparatus"
] | [
"Nucleoplasm"
] | [
"Secreted to blood"
] | [
"Hormone"
] | Approved | null | null | 1 | null | null | null | Cluster 47: Endothelial cells - Vasculature | Cluster 18: Liver cancer - Metabolism | Cluster 25: Hepatocytes - Plasma protein synthesis & secretion | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in many | 13 | Cancer enriched | Detected in single | 11 | Cancer enriched | Detected in some | 26 | Cell type enriched | Detected in some | 15 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 6,129 | 6 |
ENSG00000130175 | PRKCSH | Protein kinase C substrate 80K-H | [
"P14314"
] | 19 | 11435284-11450968 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004465",
"HPA041940",
"HPA043560"
] | [
"G19P1",
"GIIB",
"PCLD",
"PLD1",
"VASAP-60"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Endoplasmic reticulum"
] | [] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Approved | Supported | null | 33 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 30: White matter - Myelination | Cluster 23: Non-specific - Transcription | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 6,130 | 5 |
ENSG00000130176 | CNN1 | Calponin 1 | [
"P51911"
] | 19 | 11538767-11550323 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000007",
"HPA014263"
] | [
"Sm-Calp",
"SMCC"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Calmodulin-binding"
] | [
"Cancer-related genes"
] | [
"Actin filaments"
] | [] | [] | [] | Approved | Enhanced | null | 7 | No | No | null | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 64: Connective tissue cells - ECM organization | Cluster 62: Smooth muscle cells - Muscle contraction | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 6,131 | 3 |
ENSG00000130177 | CDC16 | Cell division cycle 16 | [
"Q13042"
] | 13 | 114234887-114272723 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042826"
] | [
"ANAPC6",
"APC6",
"CUT9"
] | [
"Cancer-related genes",
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis",
"Ubl conjugation pathway"
] | [] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Approved | null | 83 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 21: Non-specific - Metabolism | Cluster 19: Non-specific - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 56: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 6,132 | 2 |
ENSG00000130182 | ZSCAN10 | Zinc finger and SCAN domain containing 10 | [
"Q96SZ4"
] | 16 | 3088890-3099295 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA076826"
] | [
"ZNF206"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Centrosome"
] | [] | [] | Approved | null | null | 1 | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 34: Testis cancer - Unknown function | Cluster 63: Cytotrophoblasts - Basic cellular functions | null | Not detected | Not detected | null | Cancer enriched | Detected in single | 7 | Cancer enriched | Detected in single | 64 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 6,133 | 7 |
ENSG00000130193 | THEM6 | Thioesterase superfamily member 6 | [
"Q8WUY1"
] | 8 | 142727223-142736927 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA023255"
] | [
"C8orf55",
"DSCD75"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [
"Nuclear speckles",
"Cytosol"
] | [] | [
"Secreted - unknown location"
] | [
"No annotated function"
] | Approved | Uncertain | null | 31 | null | null | Cluster 1: T-cells - Unknown function | Cluster 18: Non-specific - Mixed function | Cluster 40: Non-specific - Unknown function | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 6,134 | 7 |
ENSG00000130202 | NECTIN2 | Nectin cell adhesion molecule 2 | [
"Q92692"
] | 19 | 44846175-44889223 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA012374",
"HPA012759",
"CAB026138"
] | [
"CD112",
"HVEB",
"Nectin-2",
"PRR2",
"PVRL2",
"PVRR2"
] | [
"CD markers",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cell adhesion",
"Host-virus interaction"
] | [
"Host cell receptor for virus entry",
"Receptor"
] | [] | [
"Vesicles"
] | [
"Plasma membrane",
"Mitotic spindle"
] | [] | [] | Approved | Enhanced | null | 26 | Yes | Yes | Cluster 19: Eosinophils - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 66: Non-specific - Mitochondria | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 6,135 | 2 |
ENSG00000130203 | APOE | Apolipoprotein E | [
"P02649"
] | 19 | 44905791-44909393 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB008363",
"HPA065539",
"HPA068768",
"CAB069921"
] | [
"AD2"
] | [
"Cancer-related genes",
"Candidate cardiovascular disease genes",
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Cholesterol metabolism",
"Host-virus interaction",
"Lipid metabolism",
"Lipid transport",
"Steroid metabolism",
"Sterol metabolism",
"Transport"
] | [
"Heparin-binding"
] | [
"Alzheimer disease",
"Amyloidosis",
"Cancer-related genes",
"Disease variant",
"Hyperlipidemia",
"Neurodegeneration"
] | [
"Vesicles"
] | [] | [
"Secreted to blood"
] | [
"Apolipoprotein"
] | Approved | Enhanced | null | 52 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 36: Brain & Liver - Signaling | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Liver Hepatocellular Carcinoma"
] | [] | [
"Liver Hepatocellular Carcinoma"
] | 6,136 | 9 |
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