ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000136319
TTC5
Tetratricopeptide repeat domain 5
[ "Q8N0Z6" ]
14
20256558-20305960
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045008", "HPA054198" ]
[ "Strap" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
12
null
null
Cluster 33: Non-specific - ATP binding
Cluster 17: Choroid plexus - Cilium
Cluster 30: Non-specific - Gene expression regulation
Cluster 7: Non-specific - Transcription
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,148
5
ENSG00000136327
NKX2-8
NK2 homeobox 8
[ "O15522" ]
14
36580004-36582614
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA062879" ]
[ "Nkx2-9", "NKX2.8", "NKX2H" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane" ]
[]
[]
Approved
Uncertain
null
1
null
null
null
Cluster 30: White matter - Myelination
Cluster 65: Non-specific - Unknown function
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 67: Testis - Mixed function
Group enriched
Detected in some
4
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,149
7
ENSG00000136352
NKX2-1
NK2 homeobox 1
[ "P43699" ]
14
36516392-36521149
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000078", "CAB053633", "HPA074316" ]
[ "BCH", "NKX2A", "TITF1", "TTF-1", "TTF1" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Biological rhythms", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding", "Repressor" ]
[ "Cancer-related genes", "Congenital hypothyroidism", "Disease variant" ]
[ "Golgi apparatus", "Vesicles" ]
[]
[]
[]
Uncertain
Enhanced
null
14
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 81: Alveolar cells - Lung function
Cluster 33: Thyroid gland - Tissue development
Group enriched
Detected in some
9
Group enriched
Detected in many
7
Group enriched
Detected in some
16
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,150
5
ENSG00000136367
ZFHX2
Zinc finger homeobox 2
[ "Q9C0A1" ]
14
23520857-23556192
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA000720", "HPA005146" ]
[ "KIAA1056", "KIAA1762", "ZFH-5", "ZNF409" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Disease variant" ]
[ "Nucleoli fibrillar center" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
2
Yes
No
null
Cluster 15: Non-specific - Transcription
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
7,151
9
ENSG00000136371
MTHFS
Methenyltetrahydrofolate synthetase
[ "P49914" ]
15
79833585-79897379
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008067", "HPA054177" ]
[ "HsT19268" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Ligase" ]
[ "Disease variant", "Epilepsy" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
3
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 30: Non-specific - Gene expression regulation
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in all
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma" ]
7,152
8
ENSG00000136378
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif 7
[ "Q9UKP4" ]
15
78759206-78811464
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045284", "HPA048453" ]
[ "ADAM-TS7", "DKFZp434H204" ]
[ "Plasma proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[]
[ "Vesicles" ]
[]
[ "Secreted to extracellular matrix" ]
[ "Enzyme" ]
Supported
Uncertain
null
37
null
null
null
Cluster 42: Choroid plexus - Mitochondria
Cluster 49: HMC-1 - Innate immune response
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 35: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,153
4
ENSG00000136379
ABHD17C
Abhydrolase domain containing 17C, depalmitoylase
[ "Q6PCB6" ]
15
80679684-80755621
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA048890" ]
[ "FAM108C1" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
Uncertain
null
12
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
7,154
6
ENSG00000136381
IREB2
Iron responsive element binding protein 2
[ "P48200" ]
15
78437431-78501453
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB032885", "HPA040371", "HPA068982" ]
[ "IRP2" ]
[ "Disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "RNA-binding" ]
[ "Disease variant", "Neurodegeneration" ]
[ "Cell Junctions" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
17
null
null
Cluster 30: Non-specific - DNA binding
Cluster 16: Non-specific - Transcription
Cluster 58: Non-specific - Nuclear processes
Cluster 18: Adrenal cortex cells - Steroidogensis
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,155
7
ENSG00000136383
ALPK3
Alpha kinase 3
[ "Q96L96" ]
15
84817356-84873479
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA026558" ]
[ "KIAA1330", "MAK", "Midori" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Developmental protein", "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Cardiomyopathy", "Disease variant" ]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 44: Non-specific - Mixed function
Cluster 33: Sarcoma - Muscle contraction
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
7,156
8
ENSG00000136425
CIB2
Calcium and integrin binding family member 2
[ "O75838" ]
15
78104606-78131535
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036697" ]
[ "DFNB48", "KIP2", "USH1J" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Transporters" ]
[]
[]
[ "Cancer-related genes", "Deafness", "Disease variant", "Non-syndromic deafness", "Retinitis pigmentosa", "Usher syndrome" ]
[ "Nucleoplasm" ]
[ "Primary cilium transition zone", "Centrosome", "Cytosol" ]
[]
[]
Uncertain
Approved
null
32
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 11: Neuronal - Sensory perception
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
5
Immune cell enriched
Detected in single
48
0
0
0
[]
[]
[]
7,158
1
ENSG00000136436
CALCOCO2
Calcium binding and coiled-coil domain 2
[ "Q13137" ]
17
48831018-48866522
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022989", "HPA023019", "HPA023195" ]
[ "MGC17318", "NDP52" ]
[ "Predicted intracellular proteins" ]
[ "Autophagy", "Host-virus interaction" ]
[]
[]
[ "Cytosol" ]
[ "Vesicles" ]
[]
[]
Supported
Enhanced
null
203
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 8: Immune cells - Immune response
Cluster 27: Breast cancer - Unknown function
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,159
1
ENSG00000136444
RSAD1
Radical S-adenosyl methionine domain containing 1
[ "Q9HA92" ]
17
50478860-50485974
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA022436", "HPA022967", "HPA024459" ]
[ "FLJ11164", "HemW" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "Chaperone" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
24
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 34: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
7,160
7
ENSG00000136448
NMT1
N-myristoyltransferase 1
[ "P30419" ]
17
44957992-45109016
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022949", "HPA022963" ]
[ "NMT" ]
[ "Enzymes", "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Acyltransferase", "Transferase" ]
[]
[ "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Supported
Supported
null
19
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 14: Neurons - Synaptic function
Cluster 27: Breast cancer - Unknown function
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[]
[ "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
7,161
8
ENSG00000136449
MYCBPAP
MYCBP associated protein
[ "Q8TBZ2" ]
17
50508425-50531501
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023257" ]
[ "AMAP-1", "DKFZp434N1415" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein" ]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Enhanced
null
14
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 51: Myeloma - Immunoglobulins
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 47: Testis - Mixed function
Tissue enriched
Detected in some
13
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
7,162
1
ENSG00000136450
SRSF1
Serine and arginine rich splicing factor 1
[ "Q07955" ]
17
58000919-58007346
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB013073", "HPA061301", "HPA069970" ]
[ "ASF", "MGC5228", "SF2", "SF2p33", "SFRS1", "SRp30a" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing", "mRNA transport", "Transport" ]
[ "RNA-binding" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Supported
null
222
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 55: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 105: Non-specific - Mixed function
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
7,163
1
ENSG00000136451
VEZF1
Vascular endothelial zinc finger 1
[ "Q14119" ]
17
57971547-57988259
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA027520", "HPA048315" ]
[ "DB1", "ZNF161" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Cardiomyopathy", "Disease variant" ]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Uncertain
null
42
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 27: Breast cancer - Unknown function
Cluster 17: Non-specific - RNA processing
Cluster 40: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
7,164
9
ENSG00000136457
CHAD
Chondroadherin
[ "O15335" ]
17
50464496-50468906
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018241" ]
[ "SLRR4A" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
null
Enhanced
null
1
null
null
Cluster 17: B-cells - Immunoglobulins
Cluster 15: Non-specific - Transcription
Cluster 27: Breast cancer - Unknown function
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
53
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
7,165
2
ENSG00000136463
TACO1
Translational activator of cytochrome c oxidase I
[ "Q9BSH4" ]
17
63600882-63608365
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021626", "HPA021643", "HPA024294" ]
[ "CCDC44" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Translation regulation" ]
[ "Activator" ]
[ "Leigh syndrome", "Primary mitochondrial disease" ]
[ "Mitochondria" ]
[]
[]
[]
Enhanced
Enhanced
null
22
null
null
Cluster 33: Non-specific - ATP binding
Cluster 45: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 15: Non-specific - Protein processing
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
7,166
1
ENSG00000136478
TEX2
Testis expressed 2
[ "Q8IWB9" ]
17
64147227-64263260
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA020648", "HPA057116" ]
[ "HT008", "KIAA1738", "TMEM96" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid transport", "Transport" ]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
21
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 27: Breast cancer - Unknown function
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
6
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,167
8
ENSG00000136485
DCAF7
DDB1 and CUL4 associated factor 7
[ "P61962" ]
17
63550222-63594286
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022948", "HPA022962" ]
[ "HAN11", "SWAN-1", "WDR68" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Developmental protein" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
186
null
null
Cluster 29: Non-specific - Unknown function
Cluster 7: Non-specific - Ribosome
Cluster 27: Breast cancer - Unknown function
Cluster 102: Non-specific - Mixed function
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,168
6
ENSG00000136488
CSH1
Chorionic somatomammotropin hormone 1
[ "P0DML2" ]
17
63894909-63896661
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB026374", "HPA043715" ]
[ "CSA", "CSMT", "FLJ75407", "hCS-A", "PL" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hormone" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Hormone" ]
null
Enhanced
null
4
null
null
null
null
Cluster 15: Kidney cancer - Membrane components
Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func.
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enriched
Detected in some
250
Group enriched
Detected in some
35
Cancer enriched
Detected in single
131
Group enriched
Detected in some
78
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,170
7
ENSG00000136490
LIMD2
LIM domain containing 2
[ "Q9BT23" ]
17
63695888-63701172
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA062432", "HPA075172" ]
[ "MGC10986" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
1
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 51: Neurons - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Head and Neck Squamous Cell Carcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma" ]
7,171
7
ENSG00000136492
BRIP1
BRCA1 interacting helicase 1
[ "Q9BX63" ]
17
61679139-61863559
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005474" ]
[ "BACH1", "FANCJ", "OF" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[ "Helicase", "Hydrolase", "Isomerase" ]
[ "Cancer-related genes", "Disease variant", "Fanconi anemia" ]
[ "Nucleoplasm", "Nuclear membrane" ]
[]
[]
[]
Supported
Approved
null
27
null
Yes
Cluster 16: Non-specific - Cell proliferation
Cluster 9: Non-specific - Receptor signaling
Cluster 27: Breast cancer - Unknown function
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
2
0
2
[]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
7,172
3
ENSG00000136504
KAT7
Lysine acetyltransferase 7
[ "O95251" ]
17
49788624-49835026
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044470", "HPA071116" ]
[ "HBO1", "HBOA", "MYST2", "ZC2HC7" ]
[ "Enzymes", "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "DNA damage", "DNA repair", "DNA replication", "Transcription", "Transcription regulation" ]
[ "Acyltransferase", "Chromatin regulator", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
61
null
null
Cluster 33: Non-specific - ATP binding
Cluster 31: Non-specific - Transcription
Cluster 27: Breast cancer - Unknown function
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,173
5
ENSG00000136514
RTP4
Receptor transporter protein 4
[ "Q96DX8" ]
3
187368385-187372076
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA064887", "HPA071189" ]
[ "IFRG28", "Z3CXXC4" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Uncertain
null
5
null
null
Cluster 33: Non-specific - ATP binding
Cluster 43: Hindbrain - Mixed function
Cluster 31: Non-specific - Antiviral immune response
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
7,174
1
ENSG00000136518
ACTL6A
Actin like 6A
[ "O96019" ]
3
179562886-179588407
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB012188", "HPA018671", "HPA063149" ]
[ "Actl6", "Arp4", "BAF53A", "INO80K", "SMARCN1" ]
[ "Disease related genes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA recombination", "DNA repair", "Growth regulation", "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Activator", "Chromatin regulator" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Enhanced
Supported
null
123
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 30: White matter - Myelination
Cluster 63: Non-specific - Protein processing
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
4
1
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
7,175
4
ENSG00000136521
NDUFB5
NADH:ubiquinone oxidoreductase subunit B5
[ "O43674" ]
3
179604690-179627647
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005640" ]
[ "CI-SGDH", "MGC12314", "SGDH" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Electron transport", "Respiratory chain", "Transport" ]
[]
[]
[ "Mitochondria" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Enhanced
null
81
null
null
Cluster 33: Non-specific - ATP binding
Cluster 23: Choroid plexus - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 52: Non-specific - Cellular respiration
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
7,176
7
ENSG00000136522
MRPL47
Mitochondrial ribosomal protein L47
[ "Q9HD33" ]
3
179588285-179604649
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037553", "HPA047779" ]
[ "CGI-204", "NCM1" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Supported
Approved
null
30
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 21: Non-specific - Metabolism
Cluster 63: Non-specific - Protein processing
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
4
2
[]
[ "Kidney Chromophobe", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
7,177
1
ENSG00000136527
TRA2B
Transformer 2 beta homolog
[ "P62995" ]
3
185914558-185938103
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB011692", "HPA063597", "HPA064972" ]
[ "Htra2-beta", "PPP1R156", "SFRS10" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "Activator", "Repressor", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
99
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 31: Non-specific - Transcription
Cluster 30: Non-specific - Gene expression regulation
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
5
0
5
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Prostate Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Prostate Adenocarcinoma" ]
7,178
7
ENSG00000136535
TBR1
T-box brain transcription factor 1
[ "Q16650" ]
2
161416297-161425870
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051256", "HPA078644", "HPA078657" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Autism spectrum disorder", "Disease variant", "Intellectual disability" ]
[]
[]
[]
[]
null
Enhanced
Supported
10
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 1: Neuronal - Visual perception
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 73: Brain - Neuronal signaling
Tissue enriched
Detected in single
39
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
5
Cell type enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,180
9
ENSG00000136536
MARCHF7
Membrane associated ring-CH-type finger 7
[ "Q9H992" ]
2
159712457-159771027
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014275", "HPA022152" ]
[ "AXOT", "MARCH-VII", "MARCH7", "RNF177" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[]
[ "Plasma membrane", "Cytosol" ]
[ "Basal body" ]
[]
[]
Approved
Enhanced
null
42
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 15: Non-specific - Transcription
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
7,181
4
ENSG00000136541
ERMN
Ermin
[ "Q8TAM6" ]
2
157318631-157327713
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038295", "HPA038296" ]
[ "ERMIN", "JN", "KIAA1189" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[ "Plasma membrane" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
1
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 30: White matter - Myelination
Cluster 51: Myeloma - Immunoglobulins
Cluster 99: Retinal pigment epithelial cells - Retinol metabolism
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in some
14
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
5
Group enriched
Detected in some
28
Low immune cell specificity
Detected in single
null
0
0
0
[]
[]
[]
7,182
3
ENSG00000136542
GALNT5
Polypeptide N-acetylgalactosaminyltransferase 5
[ "Q7Z7M9" ]
2
157257705-157318491
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA008963", "HPA009035" ]
[ "GalNAc-T5" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Golgi apparatus", "Cytosol" ]
[ "Nucleoli", "Vesicles" ]
[]
[]
Approved
Approved
null
9
null
null
null
Cluster 5: Non-specific - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 17: Intestine - Digestion
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
7,183
2
ENSG00000136546
SCN7A
Sodium voltage-gated channel alpha subunit 7
[ "Q01118" ]
2
166403573-166611482
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA072715" ]
[ "NaG", "Nav2.1", "Nav2.2", "SCN6A" ]
[ "FDA approved drug targets", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[ "FDA approved drug targets" ]
[ "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
1
null
null
Cluster 41: Basophils - Unknown function
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 5: Rhabdoid - Unknown function
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
7
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,184
7
ENSG00000136573
BLK
BLK proto-oncogene, Src family tyrosine kinase
[ "P51451" ]
8
11486894-11564599
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005093", "HPA069571" ]
[ "MGC10442" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "Diabetes mellitus" ]
[ "Nucleoplasm" ]
[]
[]
[]
Uncertain
Approved
null
42
null
null
Cluster 23: B-cells - Immunoglobulins
null
Cluster 46: Lymphoma - Humoral immune response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 66: Lymphoid tissue - Immune response
Group enriched
Detected in some
19
Cancer enriched
Detected in some
4
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in some
15
Group enriched
Detected in many
4
0
0
0
[]
[]
[]
7,186
9
ENSG00000136574
GATA4
GATA binding protein 4
[ "P43694" ]
8
11676959-11760002
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB013125", "HPA073899" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Atrial septal defect", "Cardiomyopathy", "Disease variant" ]
[ "Nuclear bodies" ]
[]
[]
[]
Supported
Uncertain
null
25
null
null
null
null
Cluster 18: Liver cancer - Metabolism
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 70: Non-specific - Protein processing
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,187
1
ENSG00000136603
SKIL
SKI like proto-oncogene
[ "P12757" ]
3
170357342-170396835
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008472", "HPA014233" ]
[ "SNO", "SnoA", "SnoN" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Uncertain
null
31
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 39: Astrocytes - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Chromophobe", "Ovary Serous Cystadenocarcinoma" ]
7,188
8
ENSG00000136628
EPRS1
Glutamyl-prolyl-tRNA synthetase 1
[ "P07814" ]
1
219968600-220046530
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026490", "HPA030052" ]
[ "EARS", "EPRS", "GLUPRORS", "PARS", "QARS", "QPRS" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Protein biosynthesis", "Translation regulation" ]
[ "Aminoacyl-tRNA synthetase", "Ligase", "Multifunctional enzyme", "RNA-binding" ]
[ "Disease variant", "Leukodystrophy", "Neurodegeneration" ]
[ "Cytosol" ]
[ "Mid piece" ]
[]
[]
Supported
Enhanced
null
73
null
null
Cluster 33: Non-specific - ATP binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 38: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
7,189
9
ENSG00000136630
HLX
H2.0 like homeobox
[ "Q14774" ]
1
220879431-220885059
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA005968" ]
[ "HB24", "HLX1" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
12
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 12: Non-specific - Vasculature
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 15: Bone marrow - Innate immune response
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
7,190
9
ENSG00000136631
VPS45
Vacuolar protein sorting 45 homolog
[ "Q9NRW7" ]
1
150067279-150145329
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027425", "HPA027441" ]
[ "h-vps45", "H1", "VPS45A", "VPS45B" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[ "Disease variant" ]
[ "Microtubules" ]
[]
[]
[]
Approved
Uncertain
null
52
null
null
Cluster 33: Non-specific - ATP binding
Cluster 31: Non-specific - Transcription
Cluster 45: Non-specific - Nuclear processes
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
7,191
4
ENSG00000136634
IL10
Interleukin 10
[ "P22301" ]
1
206767602-206774541
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB013120", "HPA071391" ]
[ "CSIF", "IL-10", "IL10A", "TGIF" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Cytokine" ]
[ "Cancer-related genes" ]
[]
[]
[ "Secreted to blood" ]
[ "Interleukin" ]
null
Approved
null
13
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 12: Non-specific - Vasculature
Cluster 71: Lymphoma - Inflammatory response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
8
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
7,192
8
ENSG00000136636
KCTD3
Potassium channel tetramerization domain containing 3
[ "Q9Y597" ]
1
215567304-215621807
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA015142" ]
[ "NY-REN-45" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
16
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 45: Non-specific - Nuclear processes
Cluster 18: Adrenal cortex cells - Steroidogensis
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
7,193
6
ENSG00000136643
RPS6KC1
Ribosomal protein S6 kinase C1
[ "Q96S38" ]
1
213051233-213274774
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026531", "HPA031565" ]
[ "humS6PKh1", "RSKL1" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Endosomes", "Lysosomes" ]
[]
[]
[]
Supported
Approved
null
3
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 53: Neurons - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
7,194
1
ENSG00000136682
ZNG1B
Zn regulated GTPase metalloprotein activator 1B
[ "Q8IUF1" ]
2
113437691-113496204
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042759", "HPA042813" ]
[ "CBWD2" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "Chaperone", "Hydrolase" ]
[]
[ "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
10
null
null
Cluster 29: Non-specific - Unknown function
Cluster 23: Choroid plexus - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 26: Keratinocytes - Keratinization
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,195
3
ENSG00000136688
IL36G
Interleukin 36 gamma
[ "Q9NZH8" ]
2
112973203-112985658
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA068168" ]
[ "IL-1F9", "IL-1H1", "IL-1RP2", "IL1E", "IL1F9", "IL1H1" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[ "Cytokine" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm", "Plasma membrane" ]
[ "Secreted to blood" ]
[ "Interleukin" ]
Supported
null
null
null
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 58: Skin - Keratinization
Group enriched
Detected in some
7
Group enriched
Detected in some
5
Group enriched
Detected in many
7
Group enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,196
1
ENSG00000136689
IL1RN
Interleukin 1 receptor antagonist
[ "P18510" ]
2
113099315-113134016
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001482", "CAB009633", "CAB080340" ]
[ "ICIL-1RA", "IL-1RN", "IL1F3", "IL1RA", "IRAP", "MGC10430" ]
[ "Cancer-related genes", "Candidate cardiovascular disease genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[ "Cancer-related genes" ]
[ "Nucleoplasm", "Cytosol" ]
[ "Centrosome" ]
[ "Secreted to blood" ]
[ "No annotated function" ]
Approved
Enhanced
null
5
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 12: Non-specific - Vasculature
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 84: Apical squamous epithelium - Cornification
Cluster 81: Squamous epithelium - Keratinization
Tissue enriched
Detected in many
4
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
5
Group enriched
Detected in many
5
3
0
3
[ "Bladder Urothelial Carcinoma" ]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
7,197
2
ENSG00000136694
IL36A
Interleukin 36 alpha
[ "Q9UHA7" ]
2
113005459-113008044
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FIL1", "FIL1E", "IL-1F6", "IL1(EPSILON)", "IL1F6", "MGC129552", "MGC129553" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[ "Cytokine" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Interleukin" ]
null
null
null
5
null
null
null
null
Cluster 59: Leukemia - T-cell receptor
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 81: Squamous epithelium - Keratinization
Group enriched
Detected in some
8
Cancer enhanced
Detected in single
null
Cancer enhanced
Detected in some
null
Cell type enriched
Detected in some
22
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,198
2
ENSG00000136695
IL36RN
Interleukin 36 receptor antagonist
[ "Q9UBH0" ]
2
113058638-113065382
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FIL1", "FIL1(DELTA)", "FIL1D", "IL-1F5", "IL1F5", "IL1HY1", "IL1L1", "IL1RP3", "IL36RA", "MGC29840" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Immunity", "Innate immunity" ]
[ "Cytokine" ]
[ "Disease variant" ]
[]
[]
[ "Secreted to blood" ]
[ "Interleukin" ]
null
null
null
26
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 84: Apical squamous epithelium - Cornification
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in some
6
Cell type enriched
Detected in some
13
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,199
8
ENSG00000136696
IL36B
Interleukin 36 beta
[ "Q9NZH7" ]
2
113022089-113052867
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035664" ]
[ "FIL1", "FILI-(ETA)", "IL-1F8", "IL-1H2", "IL1-ETA", "IL1F8", "IL1H2", "MGC126880", "MGC126882" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[ "Cytokine" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Interleukin" ]
null
Uncertain
null
1
null
null
null
null
Cluster 72: Neuronal - Signal transduction
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 58: Skin - Keratinization
Group enriched
Detected in some
5
Group enriched
Detected in some
5
Cancer enhanced
Detected in single
null
Cell type enriched
Detected in some
32
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,200
2
ENSG00000136697
IL1F10
Interleukin 1 family member 10
[ "Q8WWZ1" ]
2
113067970-113075843
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FKSG75", "IL-1F10", "IL-1HY2", "IL1-theta", "MGC11983", "MGC119832", "MGC119833" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Cytokine" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Interleukin" ]
null
null
null
1
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in some
5
Not detected
Not detected
null
Cancer enriched
Detected in single
7
Cell type enriched
Detected in single
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,201
8
ENSG00000136709
WDR33
WD repeat domain 33
[ "Q9C0J8" ]
2
127701027-127811187
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026897", "HPA046527" ]
[ "FLJ11294", "NET14", "WDC146" ]
[ "Essential proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "mRNA processing" ]
[]
[]
[ "Nucleoplasm", "Nucleoli fibrillar center" ]
[]
[]
[]
Enhanced
Supported
null
30
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 16: Non-specific - Transcription
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 7: Non-specific - Transcription
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,204
6
ENSG00000136710
CCDC115
Coiled-coil domain containing 115
[ "Q96NT0" ]
2
130337933-130342699
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034598" ]
[ "ccp1", "FLJ30131", "MGC12981" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Congenital disorder of glycosylation", "Disease variant" ]
[ "Plasma membrane" ]
[ "Vesicles" ]
[]
[]
Supported
Approved
null
19
null
null
Cluster 25: Non-specific - Unknown function
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 15: Non-specific - Protein processing
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,205
4
ENSG00000136717
BIN1
Bridging integrator 1
[ "O00499" ]
2
127048027-127107288
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB001945", "HPA003894", "HPA005437" ]
[ "AMPH2", "AMPHL", "SH3P9" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Differentiation", "Endocytosis", "Host-virus interaction" ]
[ "Developmental protein" ]
[ "Disease variant" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
46
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 11: White matter - Signal transduction
Cluster 18: Liver cancer - Metabolism
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 19: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in all
7
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
9
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
7,207
3
ENSG00000136718
IMP4
IMP U3 small nucleolar ribonucleoprotein 4
[ "Q96G21" ]
2
130342877-130347967
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA066222", "HPA066673" ]
[ "BXDC4", "MGC19606" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Ribosome biogenesis", "rRNA processing" ]
[ "Ribonucleoprotein" ]
[]
[ "Nucleoli" ]
[]
[]
[]
Enhanced
null
null
36
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 45: Non-specific - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 17: Non-specific - RNA processing
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
7,208
4
ENSG00000136720
HS6ST1
Heparan sulfate 6-O-sulfotransferase 1
[ "O60243" ]
2
128236716-128318868
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA044586" ]
[ "HS6ST" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Transferase" ]
[ "Disease variant", "Hypogonadotropic hypogonadism", "Kallmann syndrome" ]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
null
null
6
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 15: Kidney cancer - Membrane components
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,209
7
ENSG00000136732
GYPC
Glycophorin C (Gerbich blood group)
[ "P04921" ]
2
126656133-126696667
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008965", "CAB009445" ]
[ "CD236", "CD236R", "Ge", "GPC", "GYPD" ]
[ "Blood group antigen proteins", "CD markers", "Predicted membrane proteins" ]
[]
[ "Blood group antigen" ]
[]
[ "Plasma membrane" ]
[]
[]
[]
Supported
Enhanced
null
11
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 20: Macrophages & Microglia - Immune response
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 41: Striated muscle - Muscle contraction
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,211
5
ENSG00000136738
STAM
Signal transducing adaptor molecule
[ "Q92783" ]
10
17644151-17716824
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB034399", "HPA043882", "HPA060658" ]
[ "STAM1" ]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Supported
null
38
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 34: Non-specific - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 15: Bone marrow - Innate immune response
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
4
0
4
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
7,212
9
ENSG00000136750
GAD2
Glutamate decarboxylase 2
[ "Q05329" ]
10
26216665-26304558
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044637", "CAB078177" ]
[ "GAD65" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Neurotransmitter biosynthesis" ]
[ "Decarboxylase", "Lyase" ]
[]
[]
[]
[]
[]
null
Enhanced
null
36
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 10: Ciliated cells - Ion channel activity
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in some
7
Cancer enriched
Detected in single
13
Group enriched
Detected in some
22
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,213
5
ENSG00000136754
ABI1
Abl interactor 1
[ "Q8IZP0" ]
10
26746593-26861087
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB008375", "HPA068407" ]
[ "ABI-1", "E3B1", "SSH3BP1" ]
[ "Cancer-related genes", "Disease related genes", "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[]
[ "Cancer-related genes" ]
[ "Plasma membrane", "Cell Junctions" ]
[]
[]
[]
Approved
Approved
null
63
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 29: Forebrain - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
5
0
5
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
7,214
2
ENSG00000136758
YME1L1
YME1 like 1 ATPase
[ "Q96TA2" ]
10
27110111-27155266
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA066953" ]
[ "YME1L" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[ "Disease variant" ]
[ "Mitochondria" ]
[ "Nuclear bodies" ]
[]
[]
Supported
Approved
null
13
null
null
Cluster 22: Eosinophils - Transcription
Cluster 21: Non-specific - Metabolism
Cluster 52: Non-specific - Mitochondria
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
7,215
2
ENSG00000136770
DNAJC1
DnaJ heat shock protein family (Hsp40) member C1
[ "Q96KC8" ]
10
21756548-22003769
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA013432" ]
[ "DNAJL1", "ERdj1", "MTJ1" ]
[ "Predicted membrane proteins", "Transcription factors" ]
[]
[ "Chaperone", "DNA-binding" ]
[]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Approved
Approved
null
33
null
null
Cluster 33: Non-specific - ATP binding
Cluster 8: Immune cells - Immune response
Cluster 51: Myeloma - Immunoglobulins
Cluster 8: Non-specific - Secretory pathway
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
7,216
5
ENSG00000136783
NIPSNAP3A
Nipsnap homolog 3A
[ "Q9UFN0" ]
9
104747683-104760120
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042491" ]
[ "DKFZp564D177", "FLJ13953", "HSPC299", "MGC14553", "NIPSNAP4", "TassC" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
46
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 20: Macrophages & Microglia - Immune response
Cluster 43: Non-specific - Basic cellular processes
Cluster 97: Non-specific - Cellular respiration
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
7,217
5
ENSG00000136802
LRRC8A
Leucine rich repeat containing 8 VRAC subunit A
[ "Q8IWT6" ]
9
128882133-128918039
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FLJ10337", "KIAA1437", "LRRC8", "SWELL1" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Differentiation", "Ion transport", "Spermatogenesis", "Transport" ]
[ "Ion channel" ]
[]
[]
[]
[]
[]
null
null
null
10
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 19: Astrocytes - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Lung Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
7,218
4
ENSG00000136807
CDK9
Cyclin dependent kinase 9
[ "P50750" ]
9
127785679-127790792
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004216", "HPA006738" ]
[ "C-2k", "CDC2L4", "PITALRE", "TAK" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Cytoplasmic bodies" ]
[]
[]
Approved
Supported
null
175
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 29: Forebrain - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,219
7
ENSG00000136810
TXN
Thioredoxin
[ "P10599" ]
9
110243810-110256507
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB008678", "HPA047478", "HPA055752" ]
[ "TRX", "Trx80" ]
[ "Essential proteins", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Electron transport", "Transcription", "Transcription regulation", "Transport" ]
[ "Activator" ]
[ "Allergen" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[ "Intracellular and membrane" ]
[ "Transport" ]
Enhanced
Enhanced
null
61
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 27: Non-specific - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
7,220
4
ENSG00000136811
ODF2
Outer dense fiber of sperm tails 2
[ "Q5BJF6" ]
9
128455186-128501292
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001874", "HPA048841" ]
[ "CT134", "ODF84" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein" ]
[]
[ "Primary cilium", "Centrosome", "Basal body", "Connecting piece" ]
[ "Vesicles", "Microtubules", "Calyx", "Mid piece", "Principal piece" ]
[]
[]
Supported
Enhanced
null
11
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 42: Choroid plexus - Mitochondria
Cluster 43: Non-specific - Basic cellular processes
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 47: Testis - Mixed function
Tissue enriched
Detected in all
8
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
5
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
7,221
8
ENSG00000136813
ECPAS
Ecm29 proteasome adaptor and scaffold
[ "Q5VYK3" ]
9
111360685-111484745
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021646", "HPA059795" ]
[ "ECM29", "FLJ22036", "KIAA0368" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Uncertain
null
91
Yes
No
Cluster 10: Non-specific - Membrane trafficking
Cluster 14: Neurons - Synaptic function
Cluster 43: Non-specific - Basic cellular processes
Cluster 103: Non-specific - Basic cellular processes
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,222
6
ENSG00000136816
TOR1B
Torsin family 1 member B
[ "O14657" ]
9
129803157-129811281
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA013403", "HPA013697", "CAB022709" ]
[ "DQ1", "MGC4386" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Chaperone", "Hydrolase" ]
[]
[ "Nuclear speckles" ]
[ "Cytosol" ]
[]
[]
Uncertain
Approved
null
32
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 43: Non-specific - Basic cellular processes
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 17: Intestine - Digestion
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
7,223
2
ENSG00000136819
C9orf78
Chromosome 9 open reading frame 78
[ "Q9NZ63" ]
9
129827290-129835863
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021216", "HPA021232", "HPA021242" ]
[ "CSU2", "HCA59", "HSPC220" ]
[ "Predicted intracellular proteins" ]
[ "Chromosome partition", "mRNA processing", "mRNA splicing" ]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Enhanced
null
21
No
No
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 21: Non-specific - Metabolism
Cluster 43: Non-specific - Basic cellular processes
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
7,224
3
ENSG00000136824
SMC2
Structural maintenance of chromosomes 2
[ "O95347" ]
9
104094260-104141419
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA071309" ]
[ "CAP-E", "hCAP-E", "SMC2L1" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "DNA condensation", "Mitosis" ]
[]
[]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Supported
Approved
null
47
Yes
No
Cluster 33: Non-specific - ATP binding
Cluster 28: Oligodendrocytes - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
7,225
3
ENSG00000136826
KLF4
KLF transcription factor 4
[ "O43474" ]
9
107484852-107490482
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002926" ]
[ "EZF", "GKLF" ]
[ "Cancer-related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[ "Microtubules", "Cytosol" ]
[]
[]
Approved
Enhanced
null
31
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 47: Endothelial cells - Vasculature
Cluster 64: Connective tissue cells - ECM organization
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,226
7
ENSG00000136827
TOR1A
Torsin family 1 member A
[ "O14656" ]
9
129812942-129824244
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB012473", "HPA051195" ]
[ "DQ2", "DYT1" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Chaperone", "Hydrolase" ]
[ "Disease variant", "Dystonia" ]
[ "Nuclear membrane", "Vesicles" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Supported
Approved
null
31
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 14: Neurons - Synaptic function
Cluster 43: Non-specific - Basic cellular processes
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Bladder Urothelial Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
7,227
9
ENSG00000136828
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
[ "Q5JS13" ]
9
126914774-127223166
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014749" ]
[ "KIAA0351", "RALGEF2", "RALGPS1A" ]
[ "Predicted intracellular proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 14: Non-specific - Unknown function
Cluster 30: White matter - Myelination
Cluster 10: Ciliated cells - Ion channel activity
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 46: Brain & retina - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,228
2
ENSG00000136834
OR1J1
Olfactory receptor family 1 subfamily J member 1
[ "Q8NGS3" ]
9
122476958-122477926
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[ "hg32" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,230
8
ENSG00000136839
OR13C9
Olfactory receptor family 13 subfamily C member 9
[ "Q8NGT0" ]
9
104617248-104618204
Evidence at transcript level
Evidence at transcript level
No human protein/transcript evidence
Evidence at transcript level
[ "HPA078297" ]
[]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[ "Olfaction", "Sensory transduction" ]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[ "Plasma membrane" ]
[ "Nucleoplasm" ]
[]
[]
Uncertain
null
null
null
null
null
null
Cluster 24: Neurons - Mixed function
Cluster 51: Myeloma - Immunoglobulins
null
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,231
4
ENSG00000136840
ST6GALNAC4
ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
[ "Q9H4F1" ]
9
127907886-127917041
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA009042" ]
[ "SIAT3C", "SIAT7D", "ST6GALNACIV" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Golgi apparatus" ]
[ "Nucleoplasm" ]
[]
[]
Approved
null
null
1
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 55: Lymphoma - Immune response
Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response
Cluster 24: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
9
3
0
3
[]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
7,232
2
ENSG00000136842
TMOD1
Tropomodulin 1
[ "P28289" ]
9
97501180-97601743
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051202" ]
[ "D9S57E", "ETMOD", "TMOD" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[]
[]
[]
[]
null
Enhanced
null
38
null
null
Cluster 24: Non-specific - Transcription
Cluster 31: Non-specific - Transcription
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 41: Striated muscle - Muscle contraction
Tissue enhanced
Detected in all
null
Cancer enriched
Detected in many
6
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Rectum Adenocarcinoma" ]
7,233
5
ENSG00000136848
DAB2IP
DAB2 interacting protein
[ "Q5VWQ8" ]
9
121567057-121785530
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "AF9Q34", "AIP1", "DIP1/2", "KIAA1743" ]
[ "Disease related genes", "Predicted intracellular proteins" ]
[ "Angiogenesis", "Apoptosis", "Cell cycle", "Growth regulation", "Immunity", "Inflammatory response", "Innate immunity", "Stress response", "Unfolded protein response" ]
[ "Developmental protein", "GTPase activation" ]
[ "Tumor suppressor" ]
[]
[]
[]
[]
null
null
null
16
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 36: Skeletal myocytes - Muscle excitation & contraction
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
2
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
7,234
2
ENSG00000136854
STXBP1
Syntaxin binding protein 1
[ "P61764" ]
9
127579370-127696027
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008209", "HPA023483", "CAB034434" ]
[ "hUNC18", "MUNC18-1", "nSec1", "rbSec1", "UNC18" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Protein transport", "Transport" ]
[]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Nucleoli", "Basal body", "Cytosol" ]
[]
[]
Uncertain
Enhanced
null
36
null
null
Cluster 31: T-cells - T-cell receptor
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
5
2
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
7,235
3
ENSG00000136856
SLC2A8
Solute carrier family 2 member 8
[ "Q9NY64" ]
9
127397138-127408424
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA011935" ]
[ "GLUT8", "GLUTX1" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Sugar transport", "Transport" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Uncertain
null
25
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 6: Non-specific - Immune response
Cluster 32: Non-specific - Cell proliferation
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
5
6
0
6
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma", "Thyroid Carcinoma" ]
7,236
7
ENSG00000136859
ANGPTL2
Angiopoietin like 2
[ "Q9UKU9" ]
9
127087348-127122635
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040933", "HPA041299" ]
[ "ARP2", "HARP" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[ "Secreted to blood" ]
[ "No annotated function" ]
Approved
Approved
null
1
null
null
null
Cluster 26: Oligodendrocytes - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Thyroid Carcinoma" ]
[ "Thyroid Carcinoma" ]
7,237
6
ENSG00000136861
CDK5RAP2
CDK5 regulatory subunit associated protein 2
[ "Q96SN8" ]
9
120388875-120580170
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035820", "HPA035821", "HPA046529", "CAB079753" ]
[ "C48", "CEP215", "FLJ10867", "MCPH3" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Calmodulin-binding" ]
[ "Intellectual disability", "Primary microcephaly" ]
[ "Centrosome", "Basal body" ]
[ "Cell Junctions", "Cytosol", "Equatorial segment", "Mid piece", "Principal piece" ]
[]
[]
Supported
Approved
null
35
null
null
Cluster 16: Non-specific - Cell proliferation
Cluster 42: Choroid plexus - Mitochondria
Cluster 43: Non-specific - Basic cellular processes
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,238
7
ENSG00000136866
ZFP37
ZFP37 zinc finger protein
[ "Q9Y6Q3" ]
9
113038377-113056759
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA049112" ]
[ "ZNF906" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
Uncertain
null
null
Yes
No
Cluster 43: Non-specific - Transcription & Translation
Cluster 31: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,239
2
ENSG00000136867
SLC31A2
Solute carrier family 31 member 2
[ "O15432" ]
9
113150976-113164140
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014861", "CAB080265", "CAB080267" ]
[ "COPT2", "CTR2", "hCTR2" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Copper transport", "Ion transport", "Transport" ]
[]
[]
[ "Plasma membrane" ]
[ "Nuclear speckles", "Intermediate filaments" ]
[]
[]
Approved
Supported
null
10
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 30: White matter - Myelination
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 69: Parathyroid gland - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in all
12
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
7,240
3
ENSG00000136868
SLC31A1
Solute carrier family 31 member 1
[ "O15431" ]
9
113221544-113264492
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA013810" ]
[ "COPT1", "CTR1", "hCTR1" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Copper transport", "Ion transport", "Transport" ]
[]
[ "Epilepsy", "Neurodegeneration" ]
[]
[]
[]
[]
null
Approved
null
46
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 44: Non-specific - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 45: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in all
5
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,241
5
ENSG00000136869
TLR4
Toll like receptor 4
[ "O00206" ]
9
117704175-117724735
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004025", "HPA049174" ]
[ "ARMD10", "CD284", "hToll", "TLR-4" ]
[ "CD markers", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[ "Receptor" ]
[ "Age-related macular degeneration", "FDA approved drug targets" ]
[ "Golgi apparatus", "Plasma membrane" ]
[]
[ "Intracellular and membrane" ]
[ "Receptor" ]
Approved
Approved
null
25
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 39: Astrocytes - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,242
4
ENSG00000136870
ZNF189
Zinc finger protein 189
[ "O75820" ]
9
101398851-101410660
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034814" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Intermediate filaments" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 22: Eosinophils - Transcription
Cluster 34: Non-specific - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 80: Oligodendrocytes - Myelination
Cluster 22: Epididymis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,243
6
ENSG00000136872
ALDOB
Aldolase, fructose-bisphosphate B
[ "P05062" ]
9
101420560-101449664
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA002198", "CAB020827", "HPA073201" ]
[]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Glycolysis" ]
[ "Lyase" ]
[ "Cancer-related genes", "Disease variant" ]
[]
[]
[]
[]
null
Enhanced
null
15
null
null
null
Cluster 34: Non-specific - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 76: Non-specific - Metabolism
Group enriched
Detected in many
25
Cancer enriched
Detected in some
4
Cancer enriched
Detected in many
18
Cell type enriched
Detected in many
5
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
7,244
2
ENSG00000136874
STX17
Syntaxin 17
[ "P56962" ]
9
99906654-99974534
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001204" ]
[ "FLJ20651" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Autophagy", "ER-Golgi transport", "Host-virus interaction", "Transport" ]
[]
[]
[ "Nucleoli", "Cytosol" ]
[]
[]
[]
Uncertain
Approved
null
46
null
null
Cluster 1: T-cells - Unknown function
Cluster 16: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 7: Non-specific - Transcription
Cluster 38: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
7,245
8
ENSG00000136875
PRPF4
Pre-mRNA processing factor 4
[ "O43172" ]
9
113275642-113294009
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021794", "HPA022248" ]
[ "HPRP4", "HPRP4P", "PRP4", "Prp4p", "SNRNP60" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[]
[ "Disease variant", "Retinitis pigmentosa" ]
[ "Nuclear speckles" ]
[]
[]
[]
Enhanced
Enhanced
null
95
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 31: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 17: Non-specific - RNA processing
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
7,246
8
ENSG00000136878
USP20
Ubiquitin specific peptidase 20
[ "Q9Y2K6" ]
9
129834698-129881828
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA006287", "HPA007008" ]
[ "KIAA1003" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Endocytosis", "Ubl conjugation pathway" ]
[ "Hydrolase", "Protease", "Thiol protease" ]
[]
[ "Nucleoplasm", "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
Supported
63
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 1: Neurons - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 49: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
7,248
9
ENSG00000136881
BAAT
Bile acid-CoA:amino acid N-acyltransferase
[ "Q14032" ]
9
101354182-101385400
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021251", "HPA021330" ]
[ "BAT" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Fatty acid metabolism", "Lipid metabolism" ]
[ "Acyltransferase", "Hydrolase", "Serine esterase", "Transferase" ]
[ "Disease variant" ]
[ "Vesicles" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
9
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 7: Liver cancer - Metabolism
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 45: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
41
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in some
29
Cell type enriched
Detected in some
13
Not detected in immune cells
Not detected
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
7,249
4
ENSG00000136888
ATP6V1G1
ATPase H+ transporting V1 subunit G1
[ "O75348" ]
9
114587706-114598915
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004615", "HPA042898" ]
[ "ATP6G", "ATP6G1", "ATP6GL", "ATP6J", "DKFZp547P234", "Vma10" ]
[ "Essential proteins", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Hydrogen ion transport", "Ion transport", "Transport" ]
[]
[]
[ "Nucleoli" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Supported
null
61
null
null
Cluster 22: Eosinophils - Transcription
Cluster 44: Non-specific - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 97: Non-specific - Cellular respiration
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,251
9
ENSG00000136895
GARNL3
GTPase activating Rap/RanGAP domain like 3
[ "Q5VVW2" ]
9
127224265-127393660
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA028757", "HPA074886" ]
[ "bA356B19.1", "DKFZp761J1523" ]
[ "Predicted intracellular proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
null
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Thyroid Carcinoma" ]
7,253
5
ENSG00000136897
MRPL50
Mitochondrial ribosomal protein L50
[ "Q8N5N7" ]
9
101387633-101398618
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022925" ]
[ "FLJ20493", "MRP-L50" ]
[ "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Mitochondria" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
145
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 31: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 97: Non-specific - Cellular respiration
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
7,254
5
ENSG00000136908
DPM2
Dolichyl-phosphate mannosyltransferase subunit 2, regulatory
[ "O94777" ]
9
127935099-127937854
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA064623" ]
[ "MGC111193", "MGC21559" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted membrane proteins" ]
[]
[]
[ "Congenital disorder of glycosylation", "Congenital muscular dystrophy", "Disease variant", "Dystroglycanopathy" ]
[]
[]
[]
[]
null
Approved
null
4
null
null
Cluster 29: Non-specific - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 43: Non-specific - Basic cellular processes
Cluster 8: Non-specific - Secretory pathway
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
7,255
4
ENSG00000136918
WDR38
WD repeat domain 38
[ "Q5JTN6" ]
9
124853417-124857890
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA056607" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
null
null
null
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Group enriched
Detected in some
8
Not detected
Not detected
null
Group enriched
Detected in some
4
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
1
0
1
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
7,256
6
ENSG00000136925
TSTD2
Thiosulfate sulfurtransferase like domain containing 2
[ "Q5T7W7" ]
9
97600080-97633368
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA022537", "HPA024241", "HPA064304" ]
[ "C9orf97", "PP4189" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
18
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 55: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
7,257
1
ENSG00000136928
GABBR2
Gamma-aminobutyric acid type B receptor subunit 2
[ "O75899" ]
9
98288109-98708935
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA013820", "HPA031684", "CAB079065" ]
[ "GABABR2", "GPR51", "GPRC3B", "HG20" ]
[ "Disease related genes", "FDA approved drug targets", "G-protein coupled receptors", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "Disease variant", "Epilepsy", "FDA approved drug targets", "Intellectual disability" ]
[]
[]
[]
[]
null
Enhanced
Approved
9
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 48: Adipocytes & Endothelial cells - Angiogenesis
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 10: Brain - Synaptic signal transduction
Tissue enriched
Detected in some
8
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
9
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
7,258
5
ENSG00000136929
HEMGN
Hemogen
[ "Q9BXL5" ]
9
97926791-97944856
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019572", "HPA019604", "HPA019606" ]
[ "CT155", "EDAG", "NDR" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation" ]
[ "Developmental protein" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Enhanced
null
13
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 9: Non-specific - Receptor signaling
Cluster 47: Leukemia - Hemostasis
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 44: Bone marrow - Nuclear processes
Tissue enriched
Detected in some
5
Cancer enriched
Detected in some
6
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
7,259
9