ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000137507 | LRRC32 | Leucine rich repeat containing 32 | [
"Q14392"
] | 11 | 76657524-76670747 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055775",
"HPA058434"
] | [
"D11S833E",
"GARP"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Growth factor binding"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [
"Intracellular and membrane"
] | [
"Other"
] | Enhanced | null | null | 12 | null | null | Cluster 28: Neutrophils - Unknown function | Cluster 47: Endothelial cells - Vasculature | Cluster 64: Connective tissue cells - ECM organization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Skin Cutaneous Melanoma",
"Thyroid Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma",
"Thyroid Carcinoma"
] | 7,370 | 3 |
ENSG00000137509 | PRCP | Prolylcarboxypeptidase | [
"P42785"
] | 11 | 82822936-82970584 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017065",
"HPA071115"
] | [
"HUMPCP",
"PCP"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Carboxypeptidase",
"Hydrolase",
"Protease"
] | [] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Approved | null | 7 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 44: Non-specific - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 28: Liver & Adrenal gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,371 | 6 |
ENSG00000137513 | NARS2 | Asparaginyl-tRNA synthetase 2, mitochondrial | [
"Q96I59"
] | 11 | 78435620-78575194 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026793"
] | [
"DFNB94",
"FLJ23441",
"SLM5"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Ligase"
] | [
"Deafness",
"Disease variant",
"Leigh syndrome",
"Non-syndromic deafness",
"Primary mitochondrial disease"
] | [
"Mitochondria"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Supported | Supported | null | 16 | No | No | Cluster 33: Non-specific - ATP binding | Cluster 44: Non-specific - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Skin Cutaneous Melanoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Skin Cutaneous Melanoma"
] | 7,372 | 8 |
ENSG00000137522 | RNF121 | Ring finger protein 121 | [
"Q9H920"
] | 11 | 71929018-71997597 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046041"
] | [
"FLJ11099"
] | [
"Enzymes",
"Predicted membrane proteins"
] | [] | [
"Transferase"
] | [] | [
"Golgi apparatus"
] | [
"Nucleoplasm",
"Vesicles"
] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 41: Basophils - Unknown function | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 24: Non-specific - Unknown function | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 69: Parathyroid gland - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,373 | 4 |
ENSG00000137547 | MRPL15 | Mitochondrial ribosomal protein L15 | [
"Q9P015"
] | 8 | 54135241-54148514 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA044425"
] | [
"HSPC145",
"L15mt",
"MRP-L15",
"MRP-L7",
"RPML7"
] | [
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Mitochondria"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 74 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 40: Non-specific - Unknown function | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,374 | 7 |
ENSG00000137561 | TTPA | Alpha tocopherol transfer protein | [
"P49638"
] | 8 | 63048553-63086053 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"AVED"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transport"
] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | null | null | 36 | null | null | null | Cluster 19: Astrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 45: Liver - Metabolism & Coagulation | Tissue enriched | Detected in some | 38 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in some | 7 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,376 | 1 |
ENSG00000137563 | GGH | Gamma-glutamyl hydrolase | [
"Q92820"
] | 8 | 63014881-63039407 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB019296",
"HPA025226"
] | [
"GATD10"
] | [
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [] | [
"Vesicles"
] | [
"Endoplasmic reticulum"
] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Approved | null | 114 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 24: Neurons - Mixed function | Cluster 32: Non-specific - Cell proliferation | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 5 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,377 | 7 |
ENSG00000137573 | SULF1 | Sulfatase 1 | [
"Q8IWU6"
] | 8 | 69466624-69660915 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA054728"
] | [
"hSulf-1",
"KIAA1077",
"SULF-1"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Apoptosis"
] | [
"Hydrolase"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | null | Supported | null | 1 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 7,379 | 1 |
ENSG00000137574 | TGS1 | Trimethylguanosine synthase 1 | [
"Q96RS0"
] | 8 | 55773446-55826445 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA025024",
"HPA029824"
] | [
"NCOA6IP",
"PIMT"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Methyltransferase",
"Transferase"
] | [] | [
"Cytosol"
] | [] | [] | [] | Supported | Supported | null | 33 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 2: Neurons - Nucleosome | Cluster 40: Non-specific - Unknown function | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,380 | 2 |
ENSG00000137575 | SDCBP | Syndecan binding protein | [
"O00560"
] | 8 | 58552924-58582859 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB012245",
"HPA023840"
] | [
"MDA-9",
"SYCL"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Nuclear membrane"
] | [
"Intracellular and membrane"
] | [
"No annotated function"
] | Supported | Approved | null | 274 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 21: Non-specific - Metabolism | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,381 | 2 |
ENSG00000137601 | NEK1 | NIMA related kinase 1 | [
"Q96PY6"
] | 4 | 169369704-169612632 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020873",
"HPA040413"
] | [
"KIAA1901",
"NY-REN-55"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Cilium biogenesis/degradation",
"Mitosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [
"Amyotrophic lateral sclerosis",
"Ciliopathy",
"Neurodegeneration"
] | [
"Nucleoplasm"
] | [
"Primary cilium",
"Centriolar satellite",
"Cytosol"
] | [] | [] | Supported | Approved | null | 35 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 44: Non-specific - Mixed function | Cluster 22: Non-specific - mRNA splicing & Cell cycle | Cluster 103: Non-specific - Basic cellular processes | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,382 | 4 |
ENSG00000137628 | DDX60 | DExD/H-box helicase 60 | [
"Q8IY21"
] | 4 | 168216291-168318883 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046952"
] | [
"FLJ20035"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Antiviral defense",
"Immunity",
"Innate immunity"
] | [
"Helicase",
"Hydrolase",
"RNA-binding"
] | [] | [
"Cytosol"
] | [
"Intermediate filaments",
"Centrosome"
] | [] | [] | Supported | Approved | null | 3 | No | No | Cluster 33: Non-specific - ATP binding | Cluster 43: Hindbrain - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 68: Foveolar cells - Mucosal defense | Cluster 60: Stomach - Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,383 | 9 |
ENSG00000137634 | NXPE4 | Neurexophilin and PC-esterase domain family member 4 | [
"Q6UWF7"
] | 11 | 114570591-114595786 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA042801"
] | [
"C11orf33",
"FAM55D",
"FLJ20127"
] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to digestive system"
] | [
"No annotated function"
] | null | Enhanced | null | null | null | null | null | null | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration | Cluster 17: Intestine - Digestion | Group enriched | Detected in some | 13 | Not detected | Not detected | null | Group enriched | Detected in some | 15 | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,384 | 2 |
ENSG00000137642 | SORL1 | Sortilin related receptor 1 | [
"Q92673"
] | 11 | 121452314-121633763 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB011500",
"HPA031321"
] | [
"C11orf32",
"gp250",
"LR11",
"LRP9",
"SorLA",
"SorLA-1"
] | [
"Disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [
"Endocytosis",
"Transport"
] | [
"Receptor"
] | [
"Alzheimer disease",
"Amyloidosis",
"Disease variant",
"Neurodegeneration"
] | [] | [] | [
"Secreted to blood"
] | [
"Receptor"
] | null | Uncertain | null | 67 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 46: Lymphoma - Humoral immune response | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 45: Liver - Metabolism & Coagulation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,385 | 8 |
ENSG00000137648 | TMPRSS4 | Transmembrane serine protease 4 | [
"Q9NRS4"
] | 11 | 118077012-118121890 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006238"
] | [
"CAP2",
"MT-SP2",
"TMPRSS3"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Host-virus interaction"
] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | null | Uncertain | null | 69 | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 7 | 2 | 0 | 2 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,386 | 7 |
ENSG00000137656 | BUD13 | BUD13 homolog | [
"Q9BRD0"
] | 11 | 116748170-116772987 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038340",
"HPA038341"
] | [
"Cwc26",
"fSAP71",
"MGC13125"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Enhanced | null | 13 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 55: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 20: Non-specific - Transcription regulation | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Skin Cutaneous Melanoma"
] | 7,387 | 3 |
ENSG00000137672 | TRPC6 | Transient receptor potential cation channel subfamily C member 6 | [
"Q9Y210"
] | 11 | 101451564-101872562 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA045098"
] | [
"FSGS2",
"TRP6"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Calcium transport",
"Ion transport",
"Transport"
] | [
"Calcium channel",
"Ion channel"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 6 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 17: Choroid plexus - Cilium | Cluster 15: Kidney cancer - Membrane components | Cluster 110: Mural cells - ECM organization | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 6 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,388 | 6 |
ENSG00000137673 | MMP7 | Matrix metallopeptidase 7 | [
"P09237"
] | 11 | 102520508-102530750 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025869",
"HPA051358"
] | [
"MPSL1",
"PUMP-1"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Collagen degradation"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Vesicles"
] | [
"Cytosol"
] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | Approved | Supported | null | 10 | null | null | null | null | Cluster 15: Kidney cancer - Membrane components | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 13: Lung - Secretion | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 7,389 | 2 |
ENSG00000137674 | MMP20 | Matrix metallopeptidase 20 | [
"O60882"
] | 11 | 102576832-102625332 | Evidence at protein level | No human protein/transcript evidence | Evidence at protein level | Evidence at protein level | [] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted secreted proteins"
] | [] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Amelogenesis imperfecta"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | null | null | null | null | null | null | null | null | Cluster 46: Lymphoma - Humoral immune response | Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase | null | Not detected | Not detected | null | Group enriched | Detected in some | 6 | Not detected | Not detected | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,390 | 6 |
ENSG00000137675 | MMP27 | Matrix metallopeptidase 27 | [
"Q9H306"
] | 11 | 102691487-102705769 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA069097"
] | [] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Collagen degradation"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | null | Approved | null | null | null | null | null | null | Cluster 60: Prostate cancer - Unknown function | Cluster 108: Fibroblasts - ECM organization | Cluster 9: Skin - Hair follicle development | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,391 | 1 |
ENSG00000137691 | CFAP300 | Cilia and flagella associated protein 300 | [
"Q9BRQ4"
] | 11 | 102047437-102084554 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038585"
] | [
"C11orf70",
"DNAAF17",
"FBB5",
"MGC13040"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Ciliopathy",
"Disease variant",
"Kartagener syndrome",
"Primary ciliary dyskinesia"
] | [
"Primary cilium",
"Centrosome"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | null | Cluster 3: Choroid plexus - Cilium | Cluster 30: Non-specific - Gene expression regulation | Cluster 107: Ciliated cells - Cilia assembly & function | Cluster 56: Ciliated tissues - Cilium organization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,392 | 7 |
ENSG00000137692 | DCUN1D5 | Defective in cullin neddylation 1 domain containing 5 | [
"Q9BTE7"
] | 11 | 103050686-103092194 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA050863"
] | [
"FLJ32431",
"MGC2714"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 19 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 35: Non-specific - DNA binding | Cluster 30: Non-specific - Gene expression regulation | Cluster 17: Non-specific - RNA processing | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 7,393 | 6 |
ENSG00000137693 | YAP1 | Yes1 associated transcriptional regulator | [
"P46937"
] | 11 | 102110447-102233424 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009370",
"HPA038884",
"HPA038885",
"CAB069915",
"HPA070359",
"CAB080528",
"CAB080529",
"CAB080530"
] | [
"YAP-1",
"YAP65"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Repressor"
] | [
"Proto-oncogene"
] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 377 | null | null | null | Cluster 39: Astrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,394 | 4 |
ENSG00000137699 | TRIM29 | Tripartite motif containing 29 | [
"Q14134"
] | 11 | 120111286-120185529 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020053",
"HPA074841"
] | [
"ATDC",
"FLJ36085"
] | [
"Predicted intracellular proteins"
] | [
"Immunity",
"Innate immunity"
] | [] | [] | [
"Intermediate filaments"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | Approved | Enhanced | null | 45 | null | null | null | Cluster 49: Hindbrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Stomach Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma",
"Stomach Adenocarcinoma"
] | 7,395 | 2 |
ENSG00000137700 | SLC37A4 | Solute carrier family 37 member 4 | [] | 11 | 119023751-119030906 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA038939",
"HPA038940"
] | [
"G6PT",
"G6PT1",
"G6PT2",
"G6PT3",
"GSD1b",
"GSD1c",
"GSD1d",
"SPX4"
] | [
"Human disease related genes",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 3 | null | null | Cluster 24: Non-specific - Transcription | Cluster 21: Non-specific - Metabolism | Cluster 24: Non-specific - Unknown function | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 31: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,396 | 8 |
ENSG00000137707 | BTG4 | BTG anti-proliferation factor 4 | [
"Q9NY30"
] | 11 | 111467526-111514367 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA057157"
] | [
"APRO3",
"PC3B"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Endoplasmic reticulum",
"Golgi apparatus"
] | [] | [] | [] | Approved | null | null | 1 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 3: Choroid plexus - Cilium | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase | Cluster 56: Ciliated tissues - Cilium organization | Tissue enriched | Detected in some | 5 | Low cancer specificity | Detected in some | null | Not detected | Not detected | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,397 | 2 |
ENSG00000137709 | POU2F3 | POU class 2 homeobox 3 | [
"Q9UKI9"
] | 11 | 120236640-120319945 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA019652",
"HPA073468"
] | [
"Epoc-1",
"OCT11",
"PLA-1",
"Skn-1a"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 1 | null | null | null | Cluster 48: Non-specific - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 95: Tuft cells - Chemosensory signaling | Cluster 37: Skin - Keratinization | Tissue enriched | Detected in some | 8 | Cancer enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 11 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 7,398 | 1 |
ENSG00000137710 | RDX | Radixin | [
"P35241"
] | 11 | 109864295-110296712 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000263",
"HPA000763",
"CAB037312"
] | [
"DFNB24"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Actin capping",
"Actin-binding"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Plasma membrane"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Enhanced | null | 26 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 11: White matter - Signal transduction | Cluster 24: Non-specific - Unknown function | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,399 | 1 |
ENSG00000137713 | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta | [
"P30154"
] | 11 | 111726908-111766389 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB004034",
"HPA018908"
] | [
"PP2A-Abeta",
"PR65B"
] | [
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 79 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 55: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 89: Adipocytes - Lipid metabolism | Cluster 45: Liver - Metabolism & Coagulation | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 7,400 | 4 |
ENSG00000137714 | FDX1 | Ferredoxin 1 | [
"P10109"
] | 11 | 110429948-110464884 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041630",
"HPA062087"
] | [
"ADX",
"FDX"
] | [
"Predicted intracellular proteins"
] | [
"Cholesterol metabolism",
"Electron transport",
"Lipid metabolism",
"Steroid metabolism",
"Steroidogenesis",
"Sterol metabolism",
"Transport"
] | [] | [] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 1 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 28: Oligodendrocytes - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 4: Adrenal gland - Steroid metabolism | Tissue enriched | Detected in all | 7 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Skin Cutaneous Melanoma"
] | 7,401 | 1 |
ENSG00000137720 | C11orf1 | Chromosome 11 open reading frame 1 | [
"Q9H5F2"
] | 11 | 111878935-111885975 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038410",
"HPA057519"
] | [
"FLJ23499"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 32 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 21: Non-specific - Metabolism | Cluster 24: Non-specific - Unknown function | Cluster 73: Late spermatids - Spermiogenesis: Maturation | Cluster 72: Kidney - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,402 | 8 |
ENSG00000137726 | FXYD6 | FXYD domain containing ion transport regulator 6 | [
"Q9H0Q3"
] | 11 | 117836976-117877486 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041334",
"HPA042284"
] | [] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Sodium/potassium transport",
"Transport"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 44 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 14: Neurons - Synaptic function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 110: Mural cells - ECM organization | Cluster 65: Brain - Transcription | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Cancer enriched | Detected in all | 4 | Cell type enhanced | Detected in some | null | Immune cell enriched | Detected in some | 4 | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,403 | 7 |
ENSG00000137727 | ARHGAP20 | Rho GTPase activating protein 20 | [
"Q9P2F6"
] | 11 | 110577042-110713189 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA038458",
"HPA038459",
"HPA076303"
] | [
"KIAA1391"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [
"Tumor suppressor"
] | [
"Mitochondria"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | null | Cluster 33: Neurons - Mixed function | Cluster 24: Non-specific - Unknown function | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Thyroid Carcinoma"
] | [
"Thyroid Carcinoma"
] | 7,404 | 4 |
ENSG00000137731 | FXYD2 | FXYD domain containing ion transport regulator 2 | [
"P54710"
] | 11 | 117800844-117828698 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064218",
"HPA068838"
] | [
"ATP1G1",
"HOMG2",
"MGC12372"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Sodium/potassium transport",
"Transport"
] | [] | [
"Disease variant",
"FDA approved drug targets",
"Primary hypomagnesemia"
] | [
"Mitochondria"
] | [] | [] | [] | Approved | Supported | null | 1 | null | null | Cluster 24: Non-specific - Transcription | Cluster 53: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in many | 5 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 10 | Group enriched | Detected in some | 6 | Group enriched | Detected in many | 4 | 3 | 0 | 3 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,405 | 6 |
ENSG00000137745 | MMP13 | Matrix metallopeptidase 13 | [
"P45452"
] | 11 | 102942995-102955732 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002742"
] | [
"CLG3"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted secreted proteins"
] | [
"Collagen degradation"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Cancer-related genes",
"Disease variant",
"Dwarfism"
] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Enzyme"
] | null | Supported | null | null | null | null | null | null | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 11: Esophagus - Basic cellular processes | Tissue enriched | Detected in single | 12 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 7,406 | 3 |
ENSG00000137747 | TMPRSS13 | Transmembrane serine protease 13 | [
"Q9BYE2"
] | 11 | 117900641-117929459 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA079555"
] | [
"MSPL",
"MSPS",
"TMPRSS11"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins",
"Transporters"
] | [] | [
"Hydrolase",
"Protease",
"Serine protease"
] | [] | [
"Nucleoplasm",
"Plasma membrane"
] | [] | [
"Secreted in other tissues"
] | [
"Enzyme"
] | Approved | null | null | 1 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 51: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,407 | 4 |
ENSG00000137752 | CASP1 | Caspase 1 | [
"P29466"
] | 11 | 105025397-105035250 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002685",
"HPA003056"
] | [
"ICE",
"IL1BC"
] | [
"Cancer-related genes",
"Enzymes",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 25 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 31: Non-specific - Antiviral immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 5: Spleen - Immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 7,408 | 7 |
ENSG00000137757 | CASP5 | Caspase 5 | [
"P51878"
] | 11 | 104994235-105023168 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"ICE(rel)III"
] | [
"Cancer-related genes",
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | null | null | null | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 12: Non-specific - Vasculature | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 77: Intestine - Digestion | Group enriched | Detected in some | 7 | Cancer enriched | Detected in single | 5 | Group enriched | Detected in some | 6 | Cell type enhanced | Detected in some | null | Group enriched | Detected in some | 13 | 0 | 0 | 0 | [] | [] | [] | 7,409 | 6 |
ENSG00000137760 | ALKBH8 | AlkB homolog 8, tRNA methyltransferase | [
"Q96BT7"
] | 11 | 107502727-107565742 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038724",
"HPA038725",
"HPA061514"
] | [
"MGC10235",
"TRM9",
"TRMT9A"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"Multifunctional enzyme",
"RNA-binding",
"Transferase"
] | [
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Microtubules",
"Mitotic spindle",
"Primary cilium"
] | [] | [] | Supported | Approved | null | 1 | Yes | null | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 24: Non-specific - Unknown function | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 7,410 | 8 |
ENSG00000137764 | MAP2K5 | Mitogen-activated protein kinase kinase 5 | [
"Q13163"
] | 15 | 67542703-67807117 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB022094",
"HPA027347",
"HPA027755"
] | [
"HsT17454",
"MAPKK5",
"MEK5",
"PRKMK5"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [
"Microtubules",
"Primary cilium"
] | [
"Nucleoli",
"Cytokinetic bridge",
"Basal body"
] | [] | [] | Approved | Supported | null | 26 | Yes | null | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,411 | 5 |
ENSG00000137766 | UNC13C | Unc-13 homolog C | [
"Q8NB66"
] | 15 | 53978201-54628707 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA041516"
] | [
"DKFZp547H074",
"Munc13-3"
] | [
"Predicted intracellular proteins"
] | [
"Exocytosis"
] | [] | [] | [
"Vesicles"
] | [
"Cytosol"
] | [] | [] | Approved | null | null | null | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 55: Lymphoma - Immune response | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 16 | Cancer enhanced | Detected in some | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Chromophobe"
] | [] | [
"Kidney Chromophobe"
] | 7,412 | 7 |
ENSG00000137767 | SQOR | Sulfide quinone oxidoreductase | [
"Q9Y6N5"
] | 15 | 45631148-45691281 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017079",
"HPA041589"
] | [
"CGI-44",
"SQR",
"SQRDL"
] | [
"Disease related genes",
"Enzymes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 7 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 71: Lymphoma - Inflammatory response | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 17: Intestine - Digestion | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,413 | 9 |
ENSG00000137770 | CTDSPL2 | CTD small phosphatase like 2 | [
"Q05D32"
] | 15 | 44427622-44529038 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA040763",
"HPA062198"
] | [
"FLJ10523",
"HSPC129"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 22 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 31: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,414 | 6 |
ENSG00000137776 | SLTM | SAFB like transcription modulator | [
"Q9NWH9"
] | 15 | 58879050-58933679 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040256",
"HPA040381"
] | [
"FLJ13213",
"Met"
] | [
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Transcription",
"Transcription regulation"
] | [
"Repressor",
"RNA-binding"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | [] | Enhanced | Enhanced | null | 28 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,415 | 7 |
ENSG00000137802 | MAPKBP1 | Mitogen-activated protein kinase binding protein 1 | [
"O60336"
] | 15 | 41774434-41827855 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030832",
"HPA030833"
] | [
"KIAA0596",
"NPHP20"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Nephronophthisis"
] | [
"Nucleoli",
"Nucleoli rim"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 51 | No | No | Cluster 32: Basophils - Transcription | Cluster 15: Non-specific - Transcription | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 26: Keratinocytes - Keratinization | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in single | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | 7,417 | 2 |
ENSG00000137804 | NUSAP1 | Nucleolar and spindle associated protein 1 | [
"Q9BXS6"
] | 15 | 41320794-41381050 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042904",
"HPA074847"
] | [
"ANKT",
"BM037",
"FLJ13421",
"LNP",
"PRO0310p1",
"Q0310",
"SAPL"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Nucleoli",
"Nucleoli fibrillar center"
] | [] | [] | [] | Approved | Supported | null | 14 | Yes | Yes | Cluster 9: T-regs - Cell cycle regulation | null | Cluster 58: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Group enriched | Detected in some | 14 | 6 | 6 | 3 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,418 | 8 |
ENSG00000137807 | KIF23 | Kinesin family member 23 | [
"Q02241"
] | 15 | 69414246-69448427 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010414",
"HPA045208",
"HPA068831"
] | [
"KNSL5",
"MKLP-1",
"MKLP1"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Motor protein"
] | [
"Congenital dyserythropoietic anemia",
"Disease variant",
"Hereditary hemolytic anemia"
] | [
"Nucleoplasm"
] | [
"Midbody ring",
"Mitotic spindle",
"Mid piece",
"Principal piece",
"Annulus"
] | [] | [] | Supported | Uncertain | null | 78 | Yes | Yes | Cluster 25: Non-specific - Unknown function | Cluster 36: Choroid plexus - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 6 | 8 | 2 | [] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,420 | 5 |
ENSG00000137809 | ITGA11 | Integrin subunit alpha 11 | [
"Q9UKX5"
] | 15 | 68296532-68432163 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051813"
] | [
"HsT18964"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Cell adhesion"
] | [
"Integrin",
"Receptor"
] | [] | [] | [] | [] | [] | null | Uncertain | null | null | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 64: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 12: Smooth muscle tissue - ECM organization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 7,421 | 6 |
ENSG00000137812 | KNL1 | Kinetochore scaffold 1 | [
"Q8NG31"
] | 15 | 40594020-40664342 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026624",
"HPA049647"
] | [
"AF15Q14",
"CASC5",
"CT29",
"D40",
"hKNL-1",
"hSpc105",
"KIAA1570",
"MCPH4",
"PPP1R55",
"Spc7"
] | [
"Cancer-related genes",
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Chromosome partition",
"Mitosis"
] | [] | [
"Cancer-related genes",
"Disease variant",
"Intellectual disability",
"Primary microcephaly"
] | [
"Nucleoplasm"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Enhanced | null | 30 | Yes | Yes | null | Cluster 48: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 39: Testis - Nuclear processes | Group enriched | Detected in some | 6 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 7,422 | 5 |
ENSG00000137814 | HAUS2 | HAUS augmin like complex subunit 2 | [
"Q9NVX0"
] | 15 | 42548828-42569994 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA039965"
] | [
"C15orf25",
"CEP27",
"FLJ10460",
"HsT17025"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Centrosome"
] | [] | [] | Approved | Approved | null | 20 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 75: Non-specific - Chaperones and protein folding | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,423 | 7 |
ENSG00000137815 | RTF1 | RTF1 homolog, Paf1/RNA polymerase II complex component | [
"Q92541"
] | 15 | 41408408-41483563 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006714",
"CAB079946",
"CAB079947"
] | [
"KIAA0252"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation",
"Wnt signaling pathway"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Supported | null | 21 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 14: Neurons - Synaptic function | Cluster 58: Non-specific - Nuclear processes | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Lung Squamous Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,424 | 9 |
ENSG00000137817 | PARP6 | Poly(ADP-ribose) polymerase family member 6 | [
"Q2NL67"
] | 15 | 72241181-72272999 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026991"
] | [
"ARTD17",
"pART17"
] | [
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Glycosyltransferase",
"Nucleotidyltransferase",
"Transferase"
] | [] | [
"Plasma membrane"
] | [] | [] | [] | Approved | Approved | null | null | Yes | No | Cluster 25: Non-specific - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 17: Neuroblastoma - Neuronal signaling | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 27: Cerebellum - Synaptic function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma"
] | 7,425 | 6 |
ENSG00000137818 | RPLP1 | Ribosomal protein lateral stalk subunit P1 | [
"P05386"
] | 15 | 69452814-69456205 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003368"
] | [
"LP1"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Endoplasmic reticulum",
"Cytosol"
] | [] | [] | [] | Supported | null | null | 80 | null | null | Cluster 18: Non-specific - Translation | Cluster 7: Non-specific - Ribosome | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,426 | 6 |
ENSG00000137819 | PAQR5 | Progestin and adipoQ receptor family member 5 | [
"Q9NXK6"
] | 15 | 69298912-69407780 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA076729"
] | [
"FLJ20190",
"MPRG"
] | [
"Predicted membrane proteins"
] | [
"Differentiation",
"Oogenesis"
] | [
"Developmental protein",
"Receptor"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | null | null | 6 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 7: Liver cancer - Metabolism | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 72: Kidney - Transmembrane transport | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 4 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,427 | 5 |
ENSG00000137821 | LRRC49 | Leucine rich repeat containing 49 | [
"Q8IUZ0"
] | 15 | 70853239-71053658 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA015596"
] | [
"CSTPP2",
"FLJ20156",
"PGs4"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 11 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 32: Non-specific - Cell proliferation | Cluster 86: Retinal bipolar cells - Synaptic signal transduction | Cluster 35: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,428 | 3 |
ENSG00000137822 | TUBGCP4 | Tubulin gamma complex associated protein 4 | [
"Q9UGJ1"
] | 15 | 43369221-43409771 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043212"
] | [
"76P",
"FLJ14797"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Intellectual disability",
"Primary microcephaly"
] | [
"Centrosome"
] | [] | [] | [] | Supported | Approved | null | 29 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 5: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 7,429 | 9 |
ENSG00000137824 | RMDN3 | Regulator of microtubule dynamics 3 | [
"Q96TC7"
] | 15 | 40735884-40755851 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA009975",
"HPA074840"
] | [
"FAM82A2",
"FAM82C",
"FLJ10579",
"PTPIP51",
"RMD3"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Differentiation"
] | [] | [] | [
"Mitochondria"
] | [
"Cytokinetic bridge"
] | [] | [] | Enhanced | Supported | null | 53 | Yes | No | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 27: Non-specific - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 72: Macrophages - Phagocytosis & lysosomal degradation | Cluster 3: Oligodendrocytes - Myelination | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,430 | 3 |
ENSG00000137825 | ITPKA | Inositol-trisphosphate 3-kinase A | [
"P23677"
] | 15 | 41493393-41503551 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040454"
] | [
"IP3-3KA",
"IP3KA"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding",
"Kinase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Enhanced | Approved | null | null | No | null | Cluster 53: Neurons - Mixed function | Cluster 35: RS4;11 - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 4 | Immune cell enriched | Detected in single | 8 | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 7,431 | 3 |
ENSG00000137831 | UACA | Uveal autoantigen with coiled-coil domains and ankyrin repeats | [
"Q9BZF9"
] | 15 | 70654554-70763558 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA041412",
"HPA043503",
"HPA056006"
] | [
"FLJ10128",
"KIAA1561"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 19 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 64: Connective tissue cells - ECM organization | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,432 | 3 |
ENSG00000137834 | SMAD6 | SMAD family member 6 | [
"O43541"
] | 15 | 66702236-66782849 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061917"
] | [
"HsT17432",
"MADH6",
"MADH7"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [] | [
"Craniosynostosis",
"Disease variant"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [
"Golgi apparatus",
"Primary cilium",
"Basal body",
"Cytosol"
] | [] | [] | Supported | null | null | 19 | null | null | null | Cluster 42: Choroid plexus - Mitochondria | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,433 | 5 |
ENSG00000137841 | PLCB2 | Phospholipase C beta 2 | [
"Q00722"
] | 15 | 40278176-40307935 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009443",
"HPA041298",
"HPA068595",
"HPA069308"
] | [
"FLJ38135"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid degradation",
"Lipid metabolism"
] | [
"Hydrolase",
"Transducer"
] | [] | [
"Cytosol"
] | [
"Golgi apparatus",
"Plasma membrane",
"Basal body"
] | [] | [] | Approved | Enhanced | null | 3 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 20: Macrophages & Microglia - Immune response | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 40: Monocytes & Neutrophils - Inflammatory signaling | Cluster 66: Lymphoid tissue - Immune response | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in many | 5 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Lung Adenocarcinoma"
] | [] | [
"Lung Adenocarcinoma"
] | 7,434 | 9 |
ENSG00000137842 | TMEM62 | Transmembrane protein 62 | [
"Q0P6H9"
] | 15 | 43123279-43185144 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044461",
"HPA062359"
] | [
"FLJ23375"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm",
"Nucleoli fibrillar center",
"Nuclear bodies",
"Cytoplasmic bodies"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 2: Neurons - Nucleosome | Cluster 27: Breast cancer - Unknown function | Cluster 87: B-cells - Adaptive immunity: Humoral response | Cluster 17: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,435 | 6 |
ENSG00000137843 | PAK6 | P21 (RAC1) activated kinase 6 | [
"Q9NQU5"
] | 15 | 40217428-40277487 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA031124"
] | [
"PAK5"
] | [
"Enzymes",
"Plasma proteins",
"Predicted intracellular proteins",
"RAS pathway related proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Nucleoplasm",
"Nucleoli fibrillar center"
] | [
"Cell Junctions"
] | [] | [] | Supported | Approved | null | 22 | null | null | Cluster 1: T-cells - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 10: Brain - Synaptic signal transduction | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in some | null | 2 | 0 | 2 | [] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,436 | 1 |
ENSG00000137845 | ADAM10 | ADAM metallopeptidase domain 10 | [
"O14672"
] | 15 | 58588809-58749791 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001709",
"HPA050670"
] | [
"CD156C",
"HsT18717",
"kuz",
"MADM"
] | [
"Cancer-related genes",
"CD markers",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Notch signaling pathway"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [
"Alzheimer disease",
"Amyloidosis",
"Cancer-related genes",
"Disease variant",
"Neurodegeneration"
] | [
"Vesicles",
"Plasma membrane"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Approved | null | 41 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 13: Oligodendrocytes - Mixed function | Cluster 58: Non-specific - Nuclear processes | Cluster 24: Neutrophils - Innate immunity signal integration | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,437 | 3 |
ENSG00000137857 | DUOX1 | Dual oxidase 1 | [
"Q9NRD9"
] | 15 | 45129933-45165576 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA023544"
] | [
"LNOX1",
"NOXEF1",
"THOX1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Hydrogen peroxide",
"Thyroid hormones biosynthesis"
] | [
"Oxidoreductase",
"Peroxidase"
] | [] | [] | [] | [] | [] | null | Approved | null | 5 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 81: Alveolar cells - Lung function | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | 7,438 | 1 |
ENSG00000137860 | SLC28A2 | Solute carrier family 28 member 2 | [
"O43868"
] | 15 | 45252234-45277846 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA046068",
"HPA055623"
] | [
"CNT2",
"HCNT2",
"HsT17153",
"SPNT1"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Enhanced | null | 1 | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 68: Foveolar cells - Mucosal defense | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in some | 4 | Cancer enriched | Detected in single | 10 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,439 | 4 |
ENSG00000137868 | STRA6 | Signaling receptor and transporter of retinol STRA6 | [
"Q9BX79"
] | 15 | 74179466-74212267 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA040839"
] | [
"FLJ12541"
] | [
"Disease related genes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [
"Receptor"
] | [
"Disease variant",
"Microphthalmia"
] | [] | [] | [] | [] | null | Approved | null | null | null | null | null | Cluster 23: Choroid plexus - Mixed function | Cluster 70: DU4475 - Unknown function | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Breast Invasive Carcinoma"
] | [] | [
"Breast Invasive Carcinoma"
] | 7,440 | 8 |
ENSG00000137869 | CYP19A1 | Cytochrome P450 family 19 subfamily A member 1 | [
"P11511"
] | 15 | 51208057-51338601 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000355",
"HPA051194"
] | [
"ARO",
"ARO1",
"aromatase",
"CPV1",
"CYAR",
"CYP19",
"P-450AROM"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Lipid metabolism"
] | [
"Monooxygenase",
"Oxidoreductase"
] | [
"Cancer-related genes",
"Disease variant",
"FDA approved drug targets",
"Pseudohermaphroditism"
] | [
"Mitochondria"
] | [] | [] | [] | Uncertain | Enhanced | null | 17 | null | null | null | Cluster 38: Sub-cortical - Mixed function | Cluster 50: Lymphoma - Unknown function | Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal | Cluster 43: Placenta - Pregnancy hormone signaling | Tissue enriched | Detected in many | 14 | Group enriched | Detected in some | 6 | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in many | 45 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 7,441 | 8 |
ENSG00000137871 | ZNF280D | Zinc finger protein 280D | [
"Q6N043"
] | 15 | 56630176-56734086 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030233"
] | [
"FLJ20086",
"SUHW4",
"ZNF634"
] | [
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Cytosol"
] | [
"Golgi apparatus",
"Centrosome"
] | [] | [] | Approved | Approved | null | 3 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 31: Non-specific - Transcription | Cluster 58: Non-specific - Nuclear processes | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,442 | 1 |
ENSG00000137872 | SEMA6D | Semaphorin 6D | [
"Q8NFY4"
] | 15 | 47184101-47774228 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA043109"
] | [
"FLJ11598",
"KIAA1479"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein"
] | [] | [
"Plasma membrane"
] | [
"Golgi apparatus"
] | [
"Intracellular and membrane"
] | [
"Developmental protein"
] | Approved | null | null | null | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 1: Neuronal - Visual perception | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 5 | 0 | 5 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma"
] | [
"Skin Cutaneous Melanoma",
"Thyroid Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Squamous Cell Carcinoma",
"Skin Cutaneous Melanoma",
"Thyroid Carcinoma"
] | 7,443 | 4 |
ENSG00000137875 | BCL2L10 | BCL2 like 10 | [
"Q9HD36"
] | 15 | 52109263-52112775 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042222"
] | [
"BCL-B",
"Boo",
"Diva"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis"
] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 18 | null | null | Cluster 17: B-cells - Immunoglobulins | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 55: Lymphoma - Immune response | Cluster 41: Oocytes - Oogenesis | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in some | null | Cancer enhanced | Detected in many | null | Cell type enriched | Detected in some | 12 | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Lung Adenocarcinoma"
] | 7,444 | 9 |
ENSG00000137876 | RSL24D1 | Ribosomal L24 domain containing 1 | [
"Q9UHA3"
] | 15 | 55180806-55197049 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062724",
"HPA063392"
] | [
"C15orf15",
"HRP-L30-iso",
"L30",
"RPL24",
"RPL24L"
] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [
"Ribosome biogenesis"
] | [] | [] | [
"Nucleoplasm",
"Nucleoli",
"Nucleoli rim"
] | [] | [] | [] | Enhanced | Enhanced | null | 46 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 55: Non-specific - Transcription | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,445 | 6 |
ENSG00000137877 | SPTBN5 | Spectrin beta, non-erythrocytic 5 | [
"Q9NRC6"
] | 15 | 41848146-41894053 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055283"
] | [
"BSPECV",
"HUBSPECV",
"HUSPECV"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin capping",
"Actin-binding"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 1 | null | null | null | Cluster 35: Non-specific - DNA binding | Cluster 32: Non-specific - Cell proliferation | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 46: Brain & retina - Neuronal signaling | Group enriched | Detected in many | 6 | Low cancer specificity | Detected in some | null | Low cancer specificity | Detected in some | null | Cell type enriched | Detected in many | 5 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,446 | 4 |
ENSG00000137878 | GCOM1 | GCOM1, MYZAP-POLR2M combined locus | [] | 15 | 57591908-57714745 | Evidence at protein level | Evidence at protein level | null | null | [
"HPA039827",
"HPA068141"
] | [
"FLJ30973",
"GRINL1A",
"MYZAP-POLR2M"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 6 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 49: Hindbrain - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enriched | Detected in many | 5 | Cell type enhanced | Detected in some | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 7,447 | 3 |
ENSG00000137880 | GCHFR | GTP cyclohydrolase I feedback regulator | [
"P30047"
] | 15 | 40764068-40767708 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046258"
] | [
"GFRP",
"HsT16933"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | Enhanced | null | null | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 46: Lymphoma - Humoral immune response | Cluster 84: Apical squamous epithelium - Cornification | Cluster 31: Liver - Metabolism & Coagulation | Tissue enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 7,448 | 5 |
ENSG00000137936 | BCAR3 | BCAR3 adaptor protein, NSP family member | [
"O75815"
] | 1 | 93561741-93847150 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA014858"
] | [
"AND-34",
"MIG7",
"NSP2",
"SH2D3B"
] | [
"Predicted intracellular proteins"
] | [] | [
"Guanine-nucleotide releasing factor"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [
"Centrosome"
] | [] | [] | Approved | Approved | null | 21 | null | null | Cluster 32: Basophils - Transcription | Cluster 44: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 5 | 2 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 7,449 | 4 |
ENSG00000137941 | TTLL7 | Tubulin tyrosine ligase like 7 | [
"Q6ZT98"
] | 1 | 83865024-83999150 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA052249"
] | [
"FLJ23033"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein",
"Ligase"
] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | null | Cluster 11: White matter - Signal transduction | Cluster 37: Non-specific - mRNA processing | Cluster 80: Oligodendrocytes - Myelination | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,450 | 6 |
ENSG00000137942 | FNBP1L | Formin binding protein 1 like | [
"Q5T0N5"
] | 1 | 93448118-93554661 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065273"
] | [
"C1orf39",
"FLJ20275",
"TOCA1"
] | [
"Predicted intracellular proteins"
] | [
"Autophagy",
"Endocytosis"
] | [] | [] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 10 | null | null | Cluster 41: Basophils - Unknown function | Cluster 54: Immune cells - T cell receptor | Cluster 10: Ciliated cells - Ion channel activity | Cluster 38: Secretory epithelial cells - Exocrine secretion | Cluster 33: Thyroid gland - Tissue development | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Immune cell enriched | Detected in some | 5 | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 7,451 | 5 |
ENSG00000137944 | KYAT3 | Kynurenine aminotransferase 3 | [
"Q6YP21"
] | 1 | 88935773-88992953 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026538",
"HPA027168"
] | [
"CCBL2",
"KAT3",
"KATIII",
"RBM1",
"RP11-82K18.3"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Aminotransferase",
"Lyase",
"Transferase"
] | [] | [
"Cytosol"
] | [
"Nucleoli",
"Cytokinetic bridge"
] | [] | [] | Approved | Enhanced | null | 2 | Yes | null | Cluster 33: Non-specific - ATP binding | Cluster 23: Choroid plexus - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | [] | [
"Breast Invasive Carcinoma",
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 7,452 | 1 |
ENSG00000137947 | GTF2B | General transcription factor IIB | [
"Q00403"
] | 1 | 88852633-88891944 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA061626"
] | [
"TFIIB"
] | [
"Enzymes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Transcription",
"Transcription regulation"
] | [
"Acyltransferase",
"DNA-binding",
"Transferase"
] | [] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | [] | Supported | Supported | null | 84 | No | No | Cluster 35: Neutrophils - Protein binding | Cluster 50: Non-specific - Nucleic acid binding | Cluster 37: Non-specific - mRNA processing | Cluster 20: Non-specific - Transcription regulation | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,453 | 6 |
ENSG00000137948 | BRDT | Bromodomain testis associated | [
"Q58F21"
] | 1 | 91949343-92014426 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"CAB012237"
] | [
"BRD6",
"CT9"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Differentiation",
"Meiosis",
"mRNA processing",
"mRNA splicing",
"Spermatogenesis",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Chromatin regulator"
] | [
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 2 | null | null | null | Cluster 9: Non-specific - Receptor signaling | Cluster 51: Myeloma - Immunoglobulins | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 48 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 4 | Group enriched | Detected in some | 6 | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 7,454 | 5 |
ENSG00000137959 | IFI44L | Interferon induced protein 44 like | [
"Q53G44"
] | 1 | 78619902-78646145 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053247",
"HPA060372"
] | [
"C1orf29",
"GS3686",
"TLDC5B"
] | [
"Predicted intracellular proteins"
] | [
"Antiviral defense"
] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 43: Hindbrain - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Rectum Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 7,456 | 6 |
ENSG00000137960 | GIPC2 | GIPC PDZ domain containing family member 2 | [
"Q8TF65"
] | 1 | 77979542-78138444 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA051212",
"HPA062684"
] | [
"FLJ20075",
"SEMCAP-2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 8 | null | null | null | null | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 26: Kidney & Intestine - Metabolism | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 2 | 1 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 7,457 | 2 |
ENSG00000137962 | ARHGAP29 | Rho GTPase activating protein 29 | [
"Q52LW3"
] | 1 | 94148988-94275068 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026534"
] | [
"PARG1"
] | [
"Predicted intracellular proteins"
] | [] | [
"GTPase activation"
] | [] | [
"Nucleoplasm",
"Centrosome"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | Approved | Approved | null | 4 | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 15: Kidney cancer - Membrane components | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 7,458 | 6 |
ENSG00000137965 | IFI44 | Interferon induced protein 44 | [
"Q8TCB0"
] | 1 | 78649796-78664078 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027148",
"HPA043858"
] | [
"MTAP44",
"p44",
"TLDC5"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 43: Hindbrain - Mixed function | Cluster 31: Non-specific - Antiviral immune response | Cluster 104: Brain endothelial cells - Blood brain barrier | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,459 | 3 |
ENSG00000137968 | SLC44A5 | Solute carrier family 44 member 5 | [
"Q8NCS7"
] | 1 | 75202129-75611114 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA047455",
"HPA051011"
] | [
"CTL5",
"MGC34032"
] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Antiport",
"Transport"
] | [] | [] | [
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 11 | null | null | null | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 56: Non-specific - Sensory perception | Cluster 109: Neurons - Neuronal signaling | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,460 | 9 |
ENSG00000137975 | CLCA2 | Chloride channel accessory 2 | [
"Q9UQC9"
] | 1 | 86424171-86456553 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA047192"
] | [
"CLCRG2"
] | [
"Predicted membrane proteins",
"Transporters"
] | [
"Cell adhesion",
"Ion transport",
"Transport"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Plasma membrane",
"Cell Junctions"
] | [
"Nucleoplasm"
] | [
"Intracellular and membrane"
] | [
"Transport"
] | Supported | Enhanced | null | null | null | null | null | Cluster 28: Oligodendrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Group enriched | Detected in many | 6 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma"
] | 7,461 | 4 |
ENSG00000137992 | DBT | Dihydrolipoamide branched chain transacylase E2 | [
"P11182"
] | 1 | 100186919-100249834 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA026481",
"HPA026485",
"HPA026533"
] | [
"BCKAD-E2",
"BCKDH-E2",
"BCOADC-E2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Acyltransferase",
"Transferase"
] | [
"Disease variant",
"Maple syrup urine disease"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Enhanced | null | 41 | null | null | Cluster 24: Non-specific - Transcription | Cluster 28: Oligodendrocytes - Mixed function | Cluster 60: Prostate cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,463 | 6 |
ENSG00000137996 | RTCA | RNA 3'-terminal phosphate cyclase | [
"O00442"
] | 1 | 100266216-100292769 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027982",
"HPA027990",
"HPA028151",
"HPA028331"
] | [
"RPC",
"RTC1",
"RTCD1"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Ligase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Uncertain | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 34: Non-specific - Mixed function | Cluster 37: Non-specific - mRNA processing | Cluster 8: Non-specific - Secretory pathway | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 7,464 | 4 |
ENSG00000138002 | IFT172 | Intraflagellar transport 172 | [
"Q9UG01"
] | 2 | 27444377-27489805 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044893"
] | [
"BBS20",
"NPHP17",
"osm-1",
"SLB",
"wim"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein"
] | [
"Bardet-Biedl syndrome",
"Ciliopathy",
"Disease variant",
"Obesity",
"Retinitis pigmentosa"
] | [] | [] | [] | [] | null | Uncertain | null | 46 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 3: Choroid plexus - Cilium | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 90: Elongating spermatids - Spermiogenesis: Elongation | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,465 | 5 |
ENSG00000138018 | SELENOI | Selenoprotein I | [
"Q9C0D9"
] | 2 | 26308547-26395885 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA064125"
] | [
"EPT1",
"KIAA1724",
"SELI",
"SEPI"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Transferase"
] | [
"Disease variant",
"Hereditary spastic paraplegia",
"Neurodegeneration"
] | [] | [] | [] | [] | null | Approved | null | 6 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 34: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 65: Non-specific - Cell growth & division | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 7,466 | 5 |
ENSG00000138028 | CGREF1 | Cell growth regulator with EF-hand domain 1 | [
"Q99674"
] | 2 | 27098889-27119128 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA008241",
"HPA071103"
] | [
"CGR11"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Predicted secreted proteins"
] | [
"Cell adhesion",
"Cell cycle",
"Growth arrest"
] | [] | [] | [
"Golgi apparatus"
] | [] | [
"Secreted in brain"
] | [
"Cell adhesion"
] | Approved | Uncertain | null | 16 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 73: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enriched | Detected in many | 7 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | 7,467 | 3 |
ENSG00000138029 | HADHB | Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta | [
"P55084"
] | 2 | 26243170-26290465 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037539",
"HPA037540",
"HPA066099"
] | [
"MTPB"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Fatty acid metabolism",
"Lipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [
"Disease variant"
] | [
"Mitochondria"
] | [
"Equatorial segment",
"Principal piece"
] | [] | [] | Supported | Enhanced | null | 42 | No | No | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 19: Astrocytes - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 55: Myocytes - Oxidative muscle function | Cluster 52: Non-specific - Cellular respiration | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,468 | 3 |
ENSG00000138030 | KHK | Ketohexokinase | [
"P50053"
] | 2 | 27086772-27100762 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007040"
] | [] | [
"Disease related genes",
"Enzymes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Carbohydrate metabolism"
] | [
"Kinase",
"Transferase"
] | [
"Disease variant"
] | [
"Vesicles",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 1 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 37: Neurons - Mixed function | Cluster 18: Liver cancer - Metabolism | Cluster 1: Enterocytes - Absorption and Digestion | Cluster 76: Non-specific - Metabolism | Group enriched | Detected in many | 12 | Low cancer specificity | Detected in many | null | Group enriched | Detected in all | 5 | Group enriched | Detected in many | 7 | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 7,469 | 4 |
ENSG00000138031 | ADCY3 | Adenylate cyclase 3 | [
"O60266"
] | 2 | 24819169-24920237 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010223",
"HPA068616"
] | [
"AC3"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"cAMP biosynthesis",
"Olfaction",
"Sensory transduction"
] | [
"Calmodulin-binding",
"Lyase"
] | [
"Obesity"
] | [
"Nucleoplasm",
"Primary cilium"
] | [
"Nucleoli",
"Golgi apparatus",
"Plasma membrane",
"Primary cilium transition zone",
"Basal body"
] | [] | [] | Uncertain | Approved | null | 14 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 33: Neurons - Mixed function | Cluster 26: Non-specific - Mitochondria & RNA binding | Cluster 110: Mural cells - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Rectum Adenocarcinoma"
] | [] | [
"Rectum Adenocarcinoma"
] | 7,470 | 7 |
ENSG00000138032 | PPM1B | Protein phosphatase, Mg2+/Mn2+ dependent 1B | [
"O75688"
] | 2 | 44167969-44244384 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA016745"
] | [
"PP2CB",
"PP2CBETA",
"PPC2BETAX"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Nucleoli",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 27 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 102: Non-specific - Mixed function | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 7,471 | 2 |
ENSG00000138035 | PNPT1 | Polyribonucleotide nucleotidyltransferase 1 | [
"Q8TCS8"
] | 2 | 55634061-55693863 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB033424",
"HPA034602",
"HPA034603"
] | [
"DFNB70",
"old-35",
"OLD35",
"PNPase"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"Transport"
] | [
"Exonuclease",
"Hydrolase",
"Nuclease",
"Nucleotidyltransferase",
"RNA-binding",
"Transferase"
] | [
"Deafness",
"Disease variant",
"Neurodegeneration",
"Non-syndromic deafness",
"Primary mitochondrial disease",
"Spinocerebellar ataxia"
] | [
"Mitochondria"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 36 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 11: White matter - Signal transduction | Cluster 61: BICR 18 - Protein kinases | Cluster 17: Non-specific - RNA processing | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 7,472 | 7 |
ENSG00000138036 | DYNC2LI1 | Dynein cytoplasmic 2 light intermediate chain 1 | [
"Q8TCX1"
] | 2 | 43774039-43810010 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062905"
] | [
"CGI-60",
"D2LIC",
"DKFZP564A033",
"LIC3"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Cilium biogenesis/degradation"
] | [
"Developmental protein",
"Motor protein"
] | [
"Ciliopathy",
"Disease variant"
] | [
"Cytosol",
"Mid piece"
] | [
"Primary cilium",
"Basal body",
"Equatorial segment",
"Perinuclear theca",
"Principal piece",
"Annulus"
] | [] | [] | Supported | Approved | null | 15 | null | null | Cluster 32: Basophils - Transcription | Cluster 17: Choroid plexus - Cilium | Cluster 15: Kidney cancer - Membrane components | Cluster 34: Ciliated cells - Cilia assembly & function | Cluster 48: Ciliated tissues - Cilium organization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 4 | 0 | 4 | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Rectum Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Rectum Adenocarcinoma"
] | 7,473 | 4 |
ENSG00000138039 | LHCGR | Luteinizing hormone/choriogonadotropin receptor | [
"P22888"
] | 2 | 48686774-48755730 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009814",
"HPA073668"
] | [
"HHG",
"LCGR",
"LGR2",
"LHR",
"ULG5"
] | [
"Disease related genes",
"FDA approved drug targets",
"G-protein coupled receptors",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"G-protein coupled receptor",
"Receptor",
"Transducer"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Plasma membrane"
] | [
"Centriolar satellite"
] | [] | [] | Supported | Uncertain | null | 1 | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 89: Adipocytes - Lipid metabolism | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in some | null | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enriched | Detected in single | 7 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 7,474 | 8 |
ENSG00000138050 | THUMPD2 | THUMP domain containing 2 | [
"Q9BTF0"
] | 2 | 39736060-39779267 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA043042",
"HPA058025"
] | [
"C2orf8",
"MGC2454"
] | [
"Predicted intracellular proteins"
] | [] | [
"Methyltransferase",
"RNA-binding",
"Transferase"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Uncertain | Approved | null | 2 | Yes | No | Cluster 30: Non-specific - DNA binding | Cluster 16: Non-specific - Transcription | Cluster 71: Lymphoma - Inflammatory response | Cluster 7: Non-specific - Transcription | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cell type specificity | Detected in all | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 7,475 | 2 |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.