ensembl_id string | gene string | gene_description string | uniprot list | chromosome string | position string | evidence string | hpa_evidence string | uniprot_evidence string | nextprot_evidence string | antibodies list | gene_synonyms list | protein_classes list | biological_processes list | molecular_functions list | disease_involvement list | subcellular_main_locations list | subcellular_additional_locations list | secretome_locations list | secretome_functions list | reliability_if string | reliability_ih string | reliability_mouse_brain string | interactions float64 | ccd_protein string | ccd_transcript string | blood_expression_cluster string | brain_expression_cluster string | cell_line_expression_cluster string | single_cell_expression_cluster string | tissue_expression_cluster string | rna_tissue_specificity string | rna_tissue_distribution string | rna_tissue_specificity_score float64 | rna_cell_line_specificity string | rna_cell_line_distribution string | rna_cell_line_specificity_score float64 | rna_cancer_specificity string | rna_cancer_distribution string | rna_cancer_specificity_score float64 | rna_single_cell_type_specificity string | rna_single_cell_type_distribution string | rna_single_cell_type_specificity_score float64 | rna_blood_cell_specificity string | rna_blood_cell_distribution string | rna_blood_cell_specificity_score float64 | prognostic_cancer_count int64 | validated_prognostic_cancer_count int64 | potential_prognostic_cancer_count int64 | favorable_prognostic_cancers list | unfavorable_prognostic_cancers list | prognostic_cancers list | source_row_index int64 | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ENSG00000143363 | PRUNE1 | Prune exopolyphosphatase 1 | [
"Q86TP1"
] | 1 | 151008420-151035713 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028411"
] | [
"DRES-17",
"H-PRUNE",
"HTCD37",
"PRUNE"
] | [
"Disease related genes",
"Enzymes",
"Essential proteins",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Disease variant",
"Intellectual disability",
"Neurodegeneration",
"Primary microcephaly"
] | [
"Cytosol"
] | [] | [] | [] | Supported | Uncertain | null | 10 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 16: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 47: Platelets - Hemostasis | Cluster 41: Striated muscle - Muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Colon Adenocarcinoma"
] | [] | [
"Colon Adenocarcinoma"
] | 8,249 | 2 |
ENSG00000143365 | RORC | RAR related orphan receptor C | [
"P51449"
] | 1 | 151806071-151831845 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA065620"
] | [
"NR1F3",
"RORG",
"RZRG",
"TOR"
] | [
"Disease related genes",
"Human disease related genes",
"Nuclear receptors",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Biological rhythms",
"Transcription",
"Transcription regulation"
] | [
"Activator",
"Developmental protein",
"DNA-binding",
"Receptor"
] | [
"Disease variant"
] | [
"Nuclear bodies"
] | [] | [] | [] | Supported | null | null | 6 | null | null | Cluster 1: T-cells - Unknown function | Cluster 50: Non-specific - Nucleic acid binding | Cluster 71: Lymphoma - Inflammatory response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 38: Non-specific - Basic cellular processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in many | 6 | 3 | 4 | 1 | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,250 | 7 |
ENSG00000143367 | TUFT1 | Tuftelin 1 | [
"Q9NNX1"
] | 1 | 151540305-151583583 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028112",
"HPA054301"
] | [] | [
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Biomineralization"
] | [] | [
"Palmoplantar keratoderma"
] | [
"Vesicles"
] | [] | [
"Secreted - unknown location"
] | [
"Other"
] | Approved | Approved | Approved | 12 | null | Yes | Cluster 33: Non-specific - ATP binding | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 58: Skin - Keratinization | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | 8,251 | 2 |
ENSG00000143368 | SF3B4 | Splicing factor 3b subunit 4 | [
"Q15427"
] | 1 | 149923317-149927803 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028578",
"HPA064660"
] | [
"Hsh49",
"SAP49",
"SF3b49"
] | [
"Disease related genes",
"Essential proteins",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"mRNA processing",
"mRNA splicing"
] | [
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [] | [] | [] | Approved | Approved | null | 153 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 16: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 17: Non-specific - RNA processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 8,252 | 6 |
ENSG00000143373 | ZNF687 | Zinc finger protein 687 | [
"Q8N1G0"
] | 1 | 151281618-151292176 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021193",
"HPA023948"
] | [
"KIAA1441"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 26 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 6: Non-specific - Immune response | Cluster 45: Non-specific - Nuclear processes | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 8,254 | 5 |
ENSG00000143374 | TARS2 | Threonyl-tRNA synthetase 2, mitochondrial | [
"Q9BW92"
] | 1 | 150487414-150507602 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028626"
] | [
"FLJ12528",
"TARSL1"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Aminoacyl-tRNA synthetase",
"Ligase"
] | [
"Disease variant",
"Primary mitochondrial disease"
] | [
"Nucleoplasm",
"Cytosol"
] | [] | [] | [] | Uncertain | Approved | null | 48 | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 45: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,255 | 8 |
ENSG00000143375 | CGN | Cingulin | [
"Q9P2M7"
] | 1 | 151510510-151538692 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB017193",
"HPA027586",
"HPA027587",
"HPA027657"
] | [
"KIAA1319"
] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Plasma membrane",
"Cell Junctions"
] | [] | [] | [] | Supported | Enhanced | null | 28 | null | null | null | Cluster 26: Oligodendrocytes - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,256 | 3 |
ENSG00000143376 | SNX27 | Sorting nexin 27 | [
"Q96L92"
] | 1 | 151612006-151699091 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028551"
] | [
"KIAA0488",
"MGC20471",
"MY014"
] | [
"Plasma proteins",
"Predicted intracellular proteins",
"Transporters"
] | [
"Protein transport",
"Transport"
] | [] | [] | [
"Vesicles"
] | [] | [] | [] | Supported | null | null | 57 | null | null | Cluster 40: Monocytes - Innate immune response | Cluster 26: Oligodendrocytes - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in all | 5 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,257 | 6 |
ENSG00000143382 | ADAMTSL4 | ADAMTS like 4 | [
"Q6UY14"
] | 1 | 150549369-150560937 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006279"
] | [
"DKFZP434K1772",
"TSRC1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted secreted proteins"
] | [
"Apoptosis"
] | [] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [
"Secreted to extracellular matrix"
] | [
"Other"
] | Approved | Approved | null | 10 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 12: Non-specific - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 83: Epicardial mesothelial cells - Basic cellular functions | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in many | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 8,259 | 7 |
ENSG00000143384 | MCL1 | MCL1 apoptosis regulator, BCL2 family member | [
"Q07820"
] | 1 | 150560895-150579738 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002781",
"HPA008455",
"HPA031125",
"CAB068195"
] | [
"BCL2L3",
"Mcl-1"
] | [
"Cancer-related genes",
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Differentiation"
] | [
"Developmental protein"
] | [
"Cancer-related genes"
] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Enhanced | null | 63 | Yes | No | Cluster 21: Neutrophils - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 31: Neutrophils - Chemotaxis & Apoptosis | Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,260 | 4 |
ENSG00000143387 | CTSK | Cathepsin K | [
"P43235"
] | 1 | 150794880-150809577 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050346"
] | [
"CTSO",
"CTSO2",
"PKND",
"PYCD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [
"Disease variant"
] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | null | null | 4 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 36: Choroid plexus - Mixed function | Cluster 44: Connective tissue cells - ECM organization | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in all | null | Cancer enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma"
] | 8,261 | 7 |
ENSG00000143390 | RFX5 | Regulatory factor X5 | [
"P48382"
] | 1 | 151340640-151347326 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA018519",
"HPA079241"
] | [] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Disease variant",
"SCID"
] | [
"Nucleoplasm"
] | [
"Vesicles"
] | [] | [] | Supported | Supported | null | 13 | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 49: Hindbrain - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 82: Dendritic cells - Antigen presentation | Cluster 18: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 8,262 | 8 |
ENSG00000143393 | PI4KB | Phosphatidylinositol 4-kinase beta | [
"Q9UBF8"
] | 1 | 151291797-151327715 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006280",
"HPA006281",
"CAB022071"
] | [
"PI4K-BETA",
"pi4K92",
"PIK4CB"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Host-virus interaction",
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [
"Deafness",
"Disease variant",
"Non-syndromic deafness"
] | [
"Golgi apparatus"
] | [] | [] | [] | Supported | Approved | null | 27 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 11: White matter - Signal transduction | Cluster 45: Non-specific - Nuclear processes | Cluster 69: Urothelial cells - Basic cellular functions | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Pancreatic Adenocarcinoma"
] | [] | [
"Pancreatic Adenocarcinoma"
] | 8,263 | 3 |
ENSG00000143398 | PIP5K1A | Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha | [
"Q99755"
] | 1 | 151197949-151249536 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029366"
] | [] | [
"Cancer-related genes",
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid metabolism"
] | [
"Kinase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Plasma membrane",
"Cytosol"
] | [
"Nucleoplasm"
] | [] | [] | Supported | Approved | null | 9 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 48: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 8,264 | 8 |
ENSG00000143409 | MINDY1 | MINDY lysine 48 deubiquitinase 1 | [
"Q8N5J2"
] | 1 | 150996549-151008376 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028358",
"HPA061086"
] | [
"FAM63A",
"FLJ11280",
"MINDY-1"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [
"Hydrolase",
"Protease",
"Thiol protease"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Supported | null | null | 2 | null | null | Cluster 21: Neutrophils - Unknown function | Cluster 6: Non-specific - Immune response | Cluster 7: Liver cancer - Metabolism | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 82: Salivary gland - Secretion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 7 | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,266 | 5 |
ENSG00000143412 | ANXA9 | Annexin A9 | [
"O76027"
] | 1 | 150982249-150995634 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028404",
"HPA028698"
] | [
"ANX31"
] | [
"Predicted intracellular proteins"
] | [] | [
"Receptor"
] | [] | [
"Nuclear speckles",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 23 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 30: White matter - Myelination | Cluster 27: Breast cancer - Unknown function | Cluster 84: Apical squamous epithelium - Cornification | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 5 | Immune cell enhanced | Detected in some | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,267 | 4 |
ENSG00000143416 | SELENBP1 | Selenium binding protein 1 | [
"Q13228"
] | 1 | 151364304-151372707 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005741",
"CAB008366",
"HPA011731"
] | [
"hSBP",
"hSP56",
"LPSB"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"Oxidoreductase"
] | [
"Disease variant"
] | [
"Nucleoli"
] | [] | [] | [] | Supported | Enhanced | null | 33 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 39: Astrocytes - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 77: Intestine - Digestion | Tissue enhanced | Detected in all | null | Group enriched | Detected in many | 4 | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 2 | 0 | 2 | [
"Lung Adenocarcinoma"
] | [
"Skin Cutaneous Melanoma"
] | [
"Lung Adenocarcinoma",
"Skin Cutaneous Melanoma"
] | 8,268 | 4 |
ENSG00000143418 | CERS2 | Ceramide synthase 2 | [
"Q96G23"
] | 1 | 150960583-150975003 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA027262",
"HPA078737"
] | [
"FLJ10243",
"LASS2",
"SP260"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Transferase"
] | [] | [
"Nuclear membrane",
"Endoplasmic reticulum"
] | [] | [] | [] | Supported | Approved | null | 49 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 30: White matter - Myelination | Cluster 45: Non-specific - Nuclear processes | Cluster 47: Platelets - Hemostasis | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,269 | 7 |
ENSG00000143434 | SEMA6C | Semaphorin 6C | [
"Q9H3T2"
] | 1 | 151131685-151146631 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [] | [
"KIAA1869",
"Sema-Y"
] | [
"Predicted membrane proteins"
] | [
"Differentiation",
"Neurogenesis"
] | [
"Developmental protein"
] | [] | [] | [] | [] | [] | null | null | null | null | null | null | null | Cluster 15: Non-specific - Transcription | Cluster 6: Leukemia - Signal transduction | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 4 | 0 | 4 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,271 | 3 |
ENSG00000143436 | MRPL9 | Mitochondrial ribosomal protein L9 | [
"Q9BYD2"
] | 1 | 151759647-151763496 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA008579",
"HPA078399"
] | [] | [
"Essential proteins",
"Predicted intracellular proteins",
"Ribosomal proteins"
] | [] | [
"Ribonucleoprotein",
"Ribosomal protein"
] | [] | [
"Mitochondria"
] | [] | [] | [] | Enhanced | Approved | null | 105 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 27: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 15: Non-specific - Protein processing | Cluster 19: Skeletal muscle - Striated muscle contraction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Glioblastoma Multiforme"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma"
] | 8,272 | 2 |
ENSG00000143437 | ARNT | Aryl hydrocarbon receptor nuclear translocator | [
"P27540"
] | 1 | 150809713-150876708 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA001759",
"CAB004318"
] | [
"bHLHe2",
"HIF-1beta"
] | [
"Cancer-related genes",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm",
"Nuclear bodies"
] | [] | [] | [] | Supported | Supported | null | 44 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 6: Non-specific - Immune response | Cluster 45: Non-specific - Nuclear processes | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,273 | 2 |
ENSG00000143442 | POGZ | Pogo transposable element derived with ZNF domain | [
"Q7Z3K3"
] | 1 | 151402724-151459494 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006800",
"HPA008781"
] | [
"KIAA0461",
"ZNF280E",
"ZNF635"
] | [
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Cell cycle",
"Cell division",
"DNA damage",
"DNA recombination",
"DNA repair"
] | [
"DNA-binding"
] | [
"Autism spectrum disorder",
"Disease variant",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Basal body",
"Cytosol"
] | [] | [] | Supported | Enhanced | null | 103 | null | null | Cluster 32: Basophils - Transcription | Cluster 11: White matter - Signal transduction | Cluster 45: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 8,274 | 8 |
ENSG00000143443 | C1orf56 | Chromosome 1 open reading frame 56 | [
"Q9BUN1"
] | 1 | 151047751-151051986 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA037429",
"HPA037430"
] | [
"FLJ20519",
"MENT"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [] | [] | [
"Secreted to blood"
] | [
"No annotated function"
] | null | Enhanced | null | 3 | null | null | Cluster 32: Basophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in many | 7 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,275 | 6 |
ENSG00000143450 | OAZ3 | Ornithine decarboxylase antizyme 3 | [
"Q9UMX2"
] | 1 | 151762899-151771334 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030136",
"HPA045808"
] | [] | [
"Predicted intracellular proteins"
] | [
"Polyamine biosynthesis"
] | [] | [] | [
"Nucleoplasm"
] | [
"Mid piece",
"Principal piece"
] | [] | [] | Supported | null | null | 12 | null | null | Cluster 33: Non-specific - ATP binding | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 45: Non-specific - Nuclear processes | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 79: Testis - Spermatogenesis | Tissue enriched | Detected in many | 15 | Low cancer specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Cell type enriched | Detected in many | 7 | Low immune cell specificity | Detected in single | null | 2 | 0 | 2 | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Ovary Serous Cystadenocarcinoma"
] | 8,276 | 8 |
ENSG00000143452 | HORMAD1 | HORMA domain containing 1 | [
"Q86X24"
] | 1 | 150698060-150720895 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028346",
"HPA037850"
] | [
"CT46",
"DKFZP434A1315"
] | [
"Predicted intracellular proteins"
] | [
"Differentiation",
"Meiosis",
"Oogenesis",
"Spermatogenesis"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nucleoli"
] | [] | [] | Approved | Enhanced | null | 3 | Yes | No | null | null | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 3: Early primary spermatocytes - Early meiosis | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in some | 17 | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Immune cell enhanced | Detected in single | null | 0 | 0 | 0 | [] | [] | [] | 8,277 | 4 |
ENSG00000143458 | GABPB2 | GA binding protein transcription factor subunit beta 2 | [
"Q8TAK5"
] | 1 | 151070578-151125542 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028471",
"HPA058483"
] | [
"MGC29891"
] | [
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 11 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 13: Oligodendrocytes - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 55: Myocytes - Oxidative muscle function | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,279 | 7 |
ENSG00000143469 | SYT14 | Synaptotagmin 14 | [
"Q8NB59"
] | 1 | 209900923-210171389 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA036963"
] | [
"FLJ34198",
"sytXIV"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Disease variant",
"Neurodegeneration"
] | [
"Vesicles"
] | [] | [] | [] | Supported | null | null | null | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 16: Thyroid cancer - Neuronal signaling | Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling | Cluster 42: Retina - Visual perception | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in single | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,280 | 6 |
ENSG00000143473 | KCNH1 | Potassium voltage-gated channel subfamily H member 1 | [
"O95259"
] | 1 | 210676823-211134165 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014551",
"HPA019445",
"HPA076421"
] | [
"eag",
"eag1",
"h-eag",
"hEAG",
"Kv10.1"
] | [
"Disease related genes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Transport"
] | [
"Calmodulin-binding",
"Ion channel",
"Potassium channel",
"Voltage-gated channel"
] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 5 | null | null | null | Cluster 53: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 10: Brain - Synaptic signal transduction | Tissue enriched | Detected in some | 10 | Cancer enriched | Detected in many | 4 | Cancer enhanced | Detected in some | null | Cell type enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 8,281 | 3 |
ENSG00000143476 | DTL | Denticleless E3 ubiquitin protein ligase homolog | [
"Q9NZJ0"
] | 1 | 212035553-212107400 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028016",
"HPA032023",
"HPA032031"
] | [
"CDT2",
"DCAF2",
"L2DTL",
"RAMP"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Biological rhythms",
"DNA damage",
"DNA replication",
"Ubl conjugation pathway"
] | [] | [] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Supported | Supported | null | 36 | Yes | Yes | Cluster 16: Non-specific - Cell proliferation | null | Cluster 45: Non-specific - Nuclear processes | Cluster 27: Non-specific - Cell proliferation | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Group enriched | Detected in many | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 5 | 4 | 3 | [] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 8,282 | 7 |
ENSG00000143479 | DYRK3 | Dual specificity tyrosine phosphorylation regulated kinase 3 | [
"O43781"
] | 1 | 206635536-206684419 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA075041"
] | [
"hYAK3-2",
"RED",
"REDK"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Mitosis"
] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase",
"Tyrosine-protein kinase"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | null | null | 1 | null | null | Cluster 8: Plasmacytoid DCs - Unknown function | Cluster 46: Brainstem - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 103: Non-specific - Basic cellular processes | Cluster 57: Testis - Spermatogenesis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,283 | 7 |
ENSG00000143486 | EIF2D | Eukaryotic translation initiation factor 2D | [
"P41214"
] | 1 | 206571292-206612465 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028220"
] | [
"LGTN"
] | [
"Predicted intracellular proteins"
] | [
"Protein biosynthesis"
] | [
"Initiation factor"
] | [] | [
"Cytosol"
] | [
"Nuclear bodies"
] | [] | [] | Supported | Approved | null | 3 | null | null | Cluster 18: Non-specific - Translation | Cluster 11: White matter - Signal transduction | Cluster 25: Non-specific - Ribosome | Cluster 15: Non-specific - Protein processing | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 8,284 | 8 |
ENSG00000143493 | INTS7 | Integrator complex subunit 7 | [
"Q9NVH2"
] | 1 | 211940399-212035557 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA072611"
] | [
"C1orf73",
"DKFZP434B168",
"INT7"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"DNA damage"
] | [] | [] | [
"Nuclear bodies"
] | [] | [] | [] | Supported | null | null | 15 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 28: Oligodendrocytes - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 39: Testis - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma"
] | 8,285 | 9 |
ENSG00000143494 | VASH2 | Vasohibin 2 | [
"Q86V25"
] | 1 | 212950520-212992037 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA045820"
] | [
"FLJ12505"
] | [
"Enzymes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Carboxypeptidase",
"Hydrolase",
"Protease"
] | [] | [
"Cytosol"
] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | Supported | null | null | null | null | null | Cluster 13: Non-specific - Mitochondria | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 33: Sarcoma - Muscle contraction | Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response | Cluster 39: Testis - Nuclear processes | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,286 | 2 |
ENSG00000143498 | TAF1A | TATA-box binding protein associated factor, RNA polymerase I subunit A | [
"Q15573"
] | 1 | 222557902-222589933 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA054334"
] | [
"SL1",
"TAFI48"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Microtubules"
] | [
"Primary cilium",
"Primary cilium tip",
"Primary cilium transition zone",
"Basal body"
] | [] | [] | Approved | Approved | null | 27 | null | null | Cluster 12: Non-specific - Mitochondrial translation | Cluster 55: Non-specific - Transcription | Cluster 2: Mucus-secreting cells - Unknown function | Cluster 7: Non-specific - Transcription | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 8,287 | 3 |
ENSG00000143499 | SMYD2 | SET and MYND domain containing 2 | [
"Q9NRG4"
] | 1 | 214281102-214337131 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA029023"
] | [
"HSKM-B",
"KMT3C",
"ZMYND14"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Chromatin regulator",
"Methyltransferase",
"Transferase"
] | [] | [
"Cytosol"
] | [
"Mitochondria"
] | [] | [] | Approved | Uncertain | null | 20 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 52: Neurons & Synapses - Synaptic function | Cluster 70: DU4475 - Unknown function | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 41: Striated muscle - Muscle contraction | Group enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 8,288 | 1 |
ENSG00000143502 | SUSD4 | Sushi domain containing 4 | [
"Q5VX71"
] | 1 | 223220819-223364233 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA058296"
] | [
"FLJ10052"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Complement pathway",
"Immunity",
"Innate immunity"
] | [] | [] | [
"Vesicles"
] | [] | [
"Intracellular and membrane"
] | [
"Complement pathway"
] | Approved | Uncertain | null | null | null | null | Cluster 11: T-cells - Unknown function | Cluster 29: Forebrain - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 35: Neurons - Synaptic function & neurogenesis | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 1 | 0 | 1 | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,289 | 1 |
ENSG00000143512 | HHIPL2 | HHIP like 2 | [
"Q6UWX4"
] | 1 | 222522258-222548104 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA059673"
] | [
"FLJ13840",
"KIAA1822L"
] | [
"Predicted secreted proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [
"Cytosol"
] | [
"Secreted in other tissues"
] | [
"No annotated function"
] | Uncertain | Enhanced | null | 1 | No | null | null | null | Cluster 7: Liver cancer - Metabolism | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 21: Testis - Mixed function | Tissue enhanced | Detected in some | null | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in some | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [] | [
"Lung Adenocarcinoma",
"Thyroid Carcinoma"
] | [
"Lung Adenocarcinoma",
"Thyroid Carcinoma"
] | 8,291 | 4 |
ENSG00000143514 | TP53BP2 | Tumor protein p53 binding protein 2 | [
"Q13625"
] | 1 | 223779893-223845954 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA021603",
"HPA050429"
] | [
"53BP2",
"ASPP2",
"PPP1R13A"
] | [
"Cancer-related genes",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"Cell cycle"
] | [] | [
"Cancer-related genes"
] | [
"Cell Junctions",
"Cytosol"
] | [] | [] | [] | Enhanced | Supported | null | 66 | null | null | Cluster 30: Non-specific - DNA binding | Cluster 39: Astrocytes - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 51: Secretory epithelial cells - Mixed function | Cluster 78: Brain - Neuronal signaling | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 8,292 | 5 |
ENSG00000143515 | ATP8B2 | ATPase phospholipid transporting 8B2 | [
"P98198"
] | 1 | 154325525-154351304 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA046680",
"HPA061103"
] | [
"ATPID",
"KIAA1137"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Lipid transport",
"Transport"
] | [
"Translocase"
] | [] | [
"Plasma membrane"
] | [
"Nucleoli",
"Cytosol"
] | [] | [] | Supported | Approved | null | 3 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 23: Choroid plexus - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 9: T-cells - Adaptive immunity: Regulation | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in all | null | Cancer enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in many | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 8,293 | 6 |
ENSG00000143520 | FLG2 | Filaggrin 2 | [
"Q5D862"
] | 1 | 152348735-152360006 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA028699"
] | [
"IFPS"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 6 | null | null | null | null | Cluster 71: Lymphoma - Inflammatory response | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 37: Skin - Keratinization | Tissue enriched | Detected in some | 15 | Not detected | Not detected | null | Cancer enriched | Detected in some | 11 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,294 | 4 |
ENSG00000143536 | CRNN | Cornulin | [
"Q9UBG3"
] | 1 | 152409243-152414263 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA024343",
"CAB026182"
] | [
"C1orf10",
"SEP53"
] | [
"Disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [] | [] | [] | [] | null | Enhanced | null | 14 | null | null | null | null | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in many | null | Cancer enriched | Detected in single | 32 | Group enriched | Detected in many | 9 | Cell type enriched | Detected in some | 18 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,295 | 9 |
ENSG00000143537 | ADAM15 | ADAM metallopeptidase domain 15 | [
"Q13444"
] | 1 | 155050566-155062775 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA011633",
"HPA072878"
] | [
"MDC15"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Angiogenesis",
"Cell adhesion",
"Collagen degradation"
] | [
"Hydrolase",
"Metalloprotease",
"Protease"
] | [] | [
"Vesicles"
] | [] | [] | [] | Uncertain | Uncertain | null | 41 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 19: Astrocytes - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 32: Endothelial cells - Angiogenesis & vascular immunity | Cluster 58: Skin - Keratinization | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in many | 5 | 4 | 0 | 4 | [] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,296 | 7 |
ENSG00000143543 | JTB | Jumping translocation breakpoint | [
"O76095"
] | 1 | 153974269-153977674 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA006514"
] | [
"hJT",
"PAR"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted membrane proteins"
] | [
"Apoptosis",
"Cell cycle",
"Cell division",
"Mitosis"
] | [] | [
"Cancer-related genes"
] | [
"Vesicles",
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 2 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 7: Non-specific - Ribosome | Cluster 45: Non-specific - Nuclear processes | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 8,297 | 4 |
ENSG00000143545 | RAB13 | RAB13, member RAS oncogene family | [
"P51153"
] | 1 | 153981617-153986358 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003996"
] | [] | [
"Predicted intracellular proteins"
] | [
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Supported | Approved | null | 30 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 44: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 64: Renal epithelial cells - Ion transport & homeostasis | Cluster 1: Choroid plexus - Transmembrane transport | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 10 | 3 | 0 | 3 | [
"Breast Invasive Carcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 8,298 | 9 |
ENSG00000143546 | S100A8 | S100 calcium binding protein A8 | [
"P05109"
] | 1 | 153390032-153391073 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002791",
"HPA024372"
] | [
"60B8AG",
"CAGA",
"CFAG",
"CGLA",
"MRP-8",
"MRP8",
"P8",
"S100-A8"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [
"Apoptosis",
"Autophagy",
"Chemotaxis",
"Immunity",
"Inflammatory response",
"Innate immunity"
] | [
"Antimicrobial"
] | [
"Cancer-related genes"
] | [
"Intermediate filaments"
] | [
"Cytosol"
] | [
"Secreted to blood"
] | [
"Immunity"
] | Supported | Enhanced | null | 28 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 12: Non-specific - Vasculature | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 11: Esophagus - Basic cellular processes | Tissue enhanced | Detected in all | null | Group enriched | Detected in many | 6 | Cancer enhanced | Detected in all | null | Group enriched | Detected in many | 5 | Group enriched | Detected in all | 9 | 1 | 0 | 1 | [] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme"
] | 8,299 | 1 |
ENSG00000143549 | TPM3 | Tropomyosin 3 | [
"P06753"
] | 1 | 154155308-154194648 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA000261",
"HPA009066",
"HPA047089",
"HPA053624"
] | [
"NEM1",
"TRK"
] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Actin-binding",
"Muscle protein"
] | [
"Cancer-related genes",
"Disease variant",
"Nemaline myopathy",
"Proto-oncogene"
] | [
"Actin filaments"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 57 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 14: Neurons - Synaptic function | Cluster 45: Non-specific - Nuclear processes | Cluster 55: Myocytes - Oxidative muscle function | Cluster 19: Skeletal muscle - Striated muscle contraction | Group enriched | Detected in all | 12 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,300 | 1 |
ENSG00000143552 | NUP210L | Nucleoporin 210 like | [
"Q5VU65"
] | 1 | 153992690-154155116 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA047195",
"HPA064245",
"HPA066707"
] | [] | [
"Cancer-related genes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Nuclear bodies"
] | [
"Cytosol"
] | [] | [] | Approved | Enhanced | null | null | No | No | null | Cluster 6: Non-specific - Immune response | Cluster 15: Kidney cancer - Membrane components | Cluster 46: Skeletal myocytes - Muscle structure & formation | Cluster 57: Testis - Spermatogenesis | Tissue enriched | Detected in single | 41 | Not detected | Not detected | null | Not detected | Not detected | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,301 | 2 |
ENSG00000143553 | SNAPIN | SNAP associated protein | [
"O95295"
] | 1 | 153658703-153661852 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046974"
] | [
"BLOC1S7",
"BORCS3",
"SNAPAP"
] | [
"Predicted intracellular proteins",
"Transporters"
] | [
"Exocytosis",
"Host-virus interaction"
] | [] | [] | [
"Golgi apparatus"
] | [
"Nucleoli"
] | [] | [] | Approved | Approved | null | 83 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 27: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 97: Non-specific - Cellular respiration | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,302 | 2 |
ENSG00000143554 | SLC27A3 | Solute carrier family 27 member 3 | [
"Q5K4L6"
] | 1 | 153774354-153780157 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA067508",
"CAB080514",
"CAB080517"
] | [
"ACSVL3",
"FATP3",
"MGC4365"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Fatty acid metabolism",
"Lipid metabolism",
"Lipid transport",
"Transport"
] | [
"Ligase"
] | [] | [
"Endoplasmic reticulum",
"Mitochondria"
] | [] | [] | [] | Approved | Enhanced | null | 20 | Yes | No | Cluster 25: Non-specific - Unknown function | Cluster 17: Choroid plexus - Cilium | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 10: Epididymal principal cells - Sperm maturation microenvironment | Cluster 12: Smooth muscle tissue - ECM organization | Low tissue specificity | Detected in many | null | Cancer enriched | Detected in many | 5 | Cancer enhanced | Detected in all | null | Cell type enriched | Detected in many | 5 | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Ovary Serous Cystadenocarcinoma",
"Prostate Adenocarcinoma"
] | [
"Glioblastoma Multiforme"
] | [
"Glioblastoma Multiforme",
"Ovary Serous Cystadenocarcinoma",
"Prostate Adenocarcinoma"
] | 8,303 | 9 |
ENSG00000143556 | S100A7 | S100 calcium binding protein A7 | [
"P31151"
] | 1 | 153457744-153460651 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB001453",
"HPA006997",
"CAB033766"
] | [
"PSOR1",
"S100A7c"
] | [
"Cancer-related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [] | [
"Cancer-related genes"
] | [
"Cytosol"
] | [] | [
"Secreted in other tissues"
] | [
"No annotated function"
] | Supported | Enhanced | null | 37 | null | null | null | Cluster 2: Neurons - Nucleosome | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization | Cluster 81: Squamous epithelium - Keratinization | Tissue enhanced | Detected in some | null | Cancer enriched | Detected in many | 8 | Cancer enhanced | Detected in many | null | Group enriched | Detected in some | 4 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,304 | 8 |
ENSG00000143569 | UBAP2L | Ubiquitin associated protein 2 like | [
"Q14157"
] | 1 | 154220179-154271510 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA035068"
] | [
"KIAA0144",
"NICE-4"
] | [
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant",
"Intellectual disability"
] | [
"Nuclear speckles",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 41 | null | null | Cluster 7: Non-specific - Innate immune response | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 45: Non-specific - Nuclear processes | Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc | Cluster 61: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Liver Hepatocellular Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,305 | 6 |
ENSG00000143570 | SLC39A1 | Solute carrier family 39 member 1 | [
"Q9NY26"
] | 1 | 153959099-153968184 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"ZIP1",
"ZIRTL"
] | [
"Metabolic proteins",
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Ion transport",
"Transport",
"Zinc transport"
] | [] | [] | [] | [] | [] | [] | null | null | null | 9 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 44: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 14: Adipose tissue - Angiogenesis | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 4 | 0 | 4 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Head and Neck Squamous Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 8,306 | 4 |
ENSG00000143575 | HAX1 | HCLS1 associated protein X-1 | [
"O00165"
] | 1 | 154272355-154275875 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA055141",
"HPA075289"
] | [
"HAX-1",
"HCLSBP1",
"HS1BP1"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [] | [] | [
"Disease variant"
] | [
"Mitochondria"
] | [] | [] | [] | Supported | Approved | null | 46 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 27: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 67: Plasma cells - Plasma cell differentiation | Cluster 52: Non-specific - Cellular respiration | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe",
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,307 | 1 |
ENSG00000143578 | CREB3L4 | CAMP responsive element binding protein 3 like 4 | [
"Q8TEY5"
] | 1 | 153967534-153974361 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038122"
] | [
"AIbZIP",
"ATCE1",
"CREB3",
"CREB4",
"hJAL"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation",
"Unfolded protein response"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm",
"Nuclear membrane"
] | [
"Mitochondria"
] | [] | [] | Approved | Enhanced | null | 2 | No | No | Cluster 32: Basophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 27: Breast cancer - Unknown function | Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid | Cluster 38: Non-specific - Basic cellular processes | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Group enriched | Detected in all | 4 | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [] | [
"Rectum Adenocarcinoma"
] | [
"Rectum Adenocarcinoma"
] | 8,308 | 6 |
ENSG00000143590 | EFNA3 | Ephrin A3 | [
"P52797"
] | 1 | 155078837-155087538 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB010494"
] | [
"Ehk1-L",
"EPLG3",
"LERK3"
] | [
"Essential proteins",
"Predicted membrane proteins",
"RAS pathway related proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Uncertain | null | 7 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 57: Stomach & Colon cancer - Digestion | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 2: Non-specific - Mixed function | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 4 | 2 | 3 | [
"Glioblastoma Multiforme",
"Stomach Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Stomach Adenocarcinoma"
] | 8,309 | 8 |
ENSG00000143595 | AQP10 | Aquaporin 10 | [
"Q96PS8"
] | 1 | 154321090-154325325 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA062621",
"HPA065947"
] | [] | [
"Metabolic proteins",
"Predicted membrane proteins",
"Transporters"
] | [
"Transport"
] | [] | [] | [
"Plasma membrane"
] | [
"Vesicles"
] | [] | [] | Supported | Enhanced | null | 17 | null | null | null | null | Cluster 47: Leukemia - Hemostasis | Cluster 47: Platelets - Hemostasis | Cluster 7: Small intestine - Absorption and Digestion | Tissue enriched | Detected in some | 15 | Cancer enhanced | Detected in some | null | Not detected | Not detected | null | Cell type enriched | Detected in some | 30 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,310 | 1 |
ENSG00000143603 | KCNN3 | Potassium calcium-activated channel subfamily N member 3 | [
"Q9UGI6"
] | 1 | 154697455-154870281 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017990",
"HPA057127"
] | [
"hSK3",
"KCa2.3",
"SKCA3"
] | [
"Disease related genes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted membrane proteins",
"Transporters",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Transport"
] | [
"Calmodulin-binding",
"Ion channel"
] | [
"Disease variant",
"FDA approved drug targets"
] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | null | null | null | Cluster 23: B-cells - Immunoglobulins | Cluster 19: Astrocytes - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 28: Astrocytes - Homeostasis & neuron support | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 5 | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 2 | 1 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 8,311 | 2 |
ENSG00000143612 | C1orf43 | Chromosome 1 open reading frame 43 | [
"Q9BWL3"
] | 1 | 154206696-154220637 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA010725"
] | [
"DKFZp586G1722",
"NICE-3"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Mitochondria"
] | [
"Cytosol"
] | [] | [] | Supported | Approved | null | 2 | null | null | Cluster 26: Monocytes - Plasma membrane proteins | Cluster 27: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 97: Non-specific - Cellular respiration | Cluster 25: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,312 | 5 |
ENSG00000143614 | GATAD2B | GATA zinc finger domain containing 2B | [
"Q8WXI9"
] | 1 | 153789030-153923360 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA017015"
] | [
"P66beta"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Transcription",
"Transcription regulation"
] | [
"Repressor"
] | [
"Intellectual disability"
] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | Approved | null | 102 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 34: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 102: Non-specific - Mixed function | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 8,313 | 3 |
ENSG00000143621 | ILF2 | Interleukin enhancer binding factor 2 | [
"Q12905"
] | 1 | 153661788-153671028 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007484",
"HPA072048"
] | [
"NF45"
] | [
"Essential proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Transcription",
"Transcription regulation"
] | [
"Activator",
"DNA-binding"
] | [] | [
"Nucleoplasm"
] | [
"Cytosol"
] | [] | [] | Supported | Supported | null | 168 | No | No | Cluster 5: Non-specific - Cell proliferation | Cluster 21: Non-specific - Metabolism | Cluster 45: Non-specific - Nuclear processes | Cluster 17: Non-specific - RNA processing | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Liver Hepatocellular Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | 8,314 | 3 |
ENSG00000143622 | RIT1 | Ras like without CAAX 1 | [
"Q92963"
] | 1 | 155897808-155911404 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053249"
] | [
"MGC125864",
"MGC125865",
"RIBB",
"RIT",
"ROC1"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase"
] | [
"Cancer-related genes",
"Disease variant"
] | [] | [] | [] | [] | null | Approved | null | 7 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 44: Non-specific - Mixed function | Cluster 7: Liver cancer - Metabolism | Cluster 29: Neutrophils - Innate immune cellular maintenance | Cluster 11: Esophagus - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 2 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,315 | 2 |
ENSG00000143624 | INTS3 | Integrator complex subunit 3 | [
"Q68E01"
] | 1 | 153728050-153774808 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA074391"
] | [
"C1orf60",
"FLJ21919",
"INT3",
"SOSS-A"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"DNA damage",
"DNA repair"
] | [] | [] | [
"Nucleoli"
] | [
"Nucleoplasm"
] | [] | [] | Approved | Approved | null | 50 | null | null | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 45: Non-specific - Nuclear processes | Cluster 102: Non-specific - Mixed function | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in some | null | 0 | 0 | 0 | [] | [] | [] | 8,316 | 7 |
ENSG00000143627 | PKLR | Pyruvate kinase L/R | [
"P30613"
] | 1 | 155289293-155301438 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA006653",
"CAB034376",
"CAB034378"
] | [] | [
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Glycolysis"
] | [
"Allosteric enzyme",
"Kinase",
"Transferase"
] | [
"Disease variant",
"FDA approved drug targets",
"Hereditary hemolytic anemia"
] | [
"Cytosol"
] | [] | [] | [] | Approved | Enhanced | null | 2 | No | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 47: Leukemia - Hemostasis | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in some | null | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 7 | Group enriched | Detected in some | 5 | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,317 | 1 |
ENSG00000143630 | HCN3 | Hyperpolarization activated cyclic nucleotide gated potassium channel 3 | [
"Q9P1Z3"
] | 1 | 155277463-155289848 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA026584"
] | [
"KIAA1535"
] | [
"Plasma proteins",
"Predicted membrane proteins",
"Voltage-gated ion channels"
] | [
"Ion transport",
"Potassium transport",
"Sodium transport",
"Transport"
] | [
"Ion channel",
"Ligand-gated ion channel",
"Potassium channel",
"Sodium channel",
"Voltage-gated channel"
] | [] | [] | [] | [] | [] | null | Approved | null | 1 | null | null | null | Cluster 1: Neurons - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 109: Neurons - Neuronal signaling | Cluster 64: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in some | null | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 8,318 | 4 |
ENSG00000143631 | FLG | Filaggrin | [
"P20930"
] | 1 | 152302165-152325239 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB002210",
"HPA027505",
"HPA030188",
"HPA030189"
] | [] | [
"Cancer-related genes",
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Developmental protein"
] | [
"Cancer-related genes",
"Ichthyosis"
] | [
"Cytoplasmic bodies"
] | [] | [] | [] | Enhanced | Enhanced | null | 18 | null | null | null | Cluster 41: Monoamines - Neurotransmitter signalling | Cluster 15: Kidney cancer - Membrane components | Cluster 84: Apical squamous epithelium - Cornification | Cluster 37: Skin - Keratinization | Tissue enriched | Detected in some | 29 | Group enriched | Detected in many | 5 | Cancer enriched | Detected in some | 7 | Cell type enriched | Detected in some | 49 | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,319 | 1 |
ENSG00000143632 | ACTA1 | Actin alpha 1, skeletal muscle | [
"P68133"
] | 1 | 229430365-229434104 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000045",
"HPA041264",
"HPA041271"
] | [
"ACTA",
"NEM3"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Muscle protein"
] | [
"Disease variant",
"Nemaline myopathy"
] | [] | [] | [] | [] | null | Enhanced | null | 45 | null | null | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 56: Hypothalamus - Neuropeptide signaling | Cluster 34: Testis cancer - Unknown function | Cluster 36: Skeletal myocytes - Muscle excitation & contraction | Cluster 30: Skeletal muscle - Striated muscle contraction | Tissue enriched | Detected in many | 6 | Cancer enhanced | Detected in some | null | Cancer enriched | Detected in many | 4 | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,320 | 1 |
ENSG00000143633 | C1orf131 | Chromosome 1 open reading frame 131 | [
"Q8NDD1"
] | 1 | 231223763-231241187 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028452",
"HPA029920"
] | [
"DKFZp547B1713"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 2 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 25: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 97: Non-specific - Cellular respiration | Cluster 77: Intestine - Digestion | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,321 | 2 |
ENSG00000143641 | GALNT2 | Polypeptide N-acetylgalactosaminyltransferase 2 | [
"Q10471"
] | 1 | 230057990-230282122 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA011222"
] | [
"GalNAc-T2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [] | [
"Glycosyltransferase",
"Transferase"
] | [
"Congenital disorder of glycosylation",
"Disease variant"
] | [
"Golgi apparatus"
] | [] | [
"Intracellular and membrane"
] | [
"Enzyme"
] | Supported | Supported | null | 31 | null | null | Cluster 2: Dendritic cells - Unknown function | Cluster 12: Non-specific - Vasculature | Cluster 69: Skin cancer - ECM organization | Cluster 103: Non-specific - Basic cellular processes | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 5 | 2 | 4 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma",
"Lung Adenocarcinoma",
"Rectum Adenocarcinoma"
] | 8,322 | 5 |
ENSG00000143643 | TTC13 | Tetratricopeptide repeat domain 13 | [
"Q8NBP0"
] | 1 | 230906243-230978875 | Evidence at protein level | Evidence at transcript level | Evidence at transcript level | Evidence at protein level | [
"HPA018022",
"HPA051558"
] | [
"FLJ22584"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Uncertain | null | 4 | null | null | Cluster 5: Non-specific - Cell proliferation | Cluster 55: Non-specific - Transcription | Cluster 45: Non-specific - Nuclear processes | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 5: Spleen - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,323 | 5 |
ENSG00000143653 | SCCPDH | Saccharopine dehydrogenase (putative) | [
"Q8NBX0"
] | 1 | 246724409-246768137 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA050775",
"HPA076030"
] | [
"CGI-49",
"NET11"
] | [
"Metabolic proteins",
"Predicted membrane proteins"
] | [] | [
"Oxidoreductase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Enhanced | null | 5 | null | null | Cluster 41: Basophils - Unknown function | Cluster 30: White matter - Myelination | Cluster 45: Non-specific - Nuclear processes | Cluster 53: Late primary spermatocytes - Meiotic division & transition | Cluster 67: Testis - Mixed function | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Immune cell enriched | Detected in all | 20 | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,324 | 7 |
ENSG00000143669 | LYST | Lysosomal trafficking regulator | [
"Q99698"
] | 1 | 235661041-235883724 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA053366",
"HPA055725"
] | [
"CHS",
"CHS1",
"Mauve"
] | [
"Disease related genes",
"Human disease related genes",
"Predicted intracellular proteins"
] | [
"Phagocytosis",
"Protein transport",
"Transport"
] | [] | [
"Disease variant"
] | [
"Nucleoplasm"
] | [
"Plasma membrane",
"Centriolar satellite"
] | [] | [] | Supported | null | null | 8 | Yes | No | Cluster 37: Monocytes & Neutrophils - Innate immune response | Cluster 5: Non-specific - Mixed function | Cluster 14: Myeloid leukemia - Innate immune response | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 44: Bone marrow - Nuclear processes | Tissue enhanced | Detected in all | null | Cancer enhanced | Detected in all | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in all | null | Immune cell enhanced | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,325 | 7 |
ENSG00000143674 | MAP3K21 | Mitogen-activated protein kinase kinase kinase 21 | [
"Q5TCX8"
] | 1 | 233327724-233385148 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA007636"
] | [
"KIAA1804",
"MLK4"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Uncertain | null | 34 | null | null | null | Cluster 10: Cerebellum - Nucleic acid binding | Cluster 15: Kidney cancer - Membrane components | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 8: Pancreas - Proteolysis | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Immune cell enriched | Detected in single | 5 | 1 | 0 | 1 | [
"Lung Squamous Cell Carcinoma"
] | [] | [
"Lung Squamous Cell Carcinoma"
] | 8,326 | 2 |
ENSG00000143702 | CEP170 | Centrosomal protein 170 | [
"Q5SW79"
] | 1 | 243124428-243255348 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA042151",
"HPA045597",
"HPA045787"
] | [
"FAM68A",
"KAB",
"KIAA0470"
] | [
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [] | [] | [] | [
"Centrosome",
"Basal body"
] | [
"Cytosol"
] | [] | [] | Supported | Uncertain | null | 76 | null | No | Cluster 38: Monocytes & Neutrophils - Degranulation | Cluster 30: White matter - Myelination | Cluster 72: Neuronal - Signal transduction | Cluster 74: Microglia - Neuroimmunity & neuroinflammation | Cluster 39: Testis - Nuclear processes | Group enriched | Detected in all | 5 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 8,327 | 2 |
ENSG00000143742 | SRP9 | Signal recognition particle 9 | [
"P49458"
] | 1 | 225777813-225790468 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [] | [
"Essential proteins",
"Predicted intracellular proteins",
"Transporters"
] | [] | [
"Ribonucleoprotein",
"RNA-binding"
] | [] | [] | [] | [] | [] | null | null | null | 267 | null | null | Cluster 9: T-regs - Cell cycle regulation | Cluster 21: Non-specific - Metabolism | Cluster 45: Non-specific - Nuclear processes | Cluster 97: Non-specific - Cellular respiration | Cluster 76: Non-specific - Metabolism | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | 8,330 | 5 |
ENSG00000143748 | NVL | Nuclear VCP like | [
"O15381"
] | 1 | 224227334-224330189 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028207",
"HPA028219",
"HPA028224",
"HPA028654"
] | [
"NVL2"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Ribosome biogenesis"
] | [] | [] | [
"Nucleoli"
] | [] | [] | [] | Enhanced | Supported | null | 13 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 4: Non-specific - mRNA splicing & Cell cycle | Cluster 45: Non-specific - Nuclear processes | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 49: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in many | null | 1 | 0 | 1 | [
"Glioblastoma Multiforme"
] | [] | [
"Glioblastoma Multiforme"
] | 8,331 | 3 |
ENSG00000143751 | SDE2 | SDE2 telomere maintenance homolog | [
"Q6IQ49"
] | 1 | 225982702-225999343 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028467",
"HPA031255",
"HPA031256"
] | [
"C1orf55",
"FLJ35382"
] | [
"Essential proteins",
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"DNA replication",
"Mitosis",
"mRNA processing",
"mRNA splicing",
"Ribosome biogenesis"
] | [
"DNA-binding",
"RNA-binding"
] | [] | [
"Nuclear speckles"
] | [
"Golgi apparatus",
"Plasma membrane",
"Cytosol"
] | [] | [] | Supported | Approved | null | 1 | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 47: Leukemia - Hemostasis | Cluster 17: Non-specific - RNA processing | Cluster 44: Bone marrow - Nuclear processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,332 | 7 |
ENSG00000143753 | DEGS1 | Delta 4-desaturase, sphingolipid 1 | [
"O15121"
] | 1 | 224175756-224193441 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA076422"
] | [
"DEGS-1",
"Des-1",
"DES1",
"FADS7",
"MLD"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted membrane proteins"
] | [
"Fatty acid biosynthesis",
"Fatty acid metabolism",
"Lipid biosynthesis",
"Lipid metabolism"
] | [
"Isomerase",
"Oxidoreductase"
] | [
"Disease variant",
"Leukodystrophy"
] | [
"Mitochondria"
] | [
"Plasma membrane",
"Cytokinetic bridge",
"Primary cilium"
] | [] | [] | Supported | null | null | 7 | Yes | null | Cluster 2: Dendritic cells - Unknown function | Cluster 20: Macrophages & Microglia - Immune response | Cluster 45: Non-specific - Nuclear processes | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 37: Skin - Keratinization | Tissue enriched | Detected in all | 4 | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 3 | 0 | 3 | [] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Liver Hepatocellular Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 8,333 | 8 |
ENSG00000143756 | FBXO28 | F-box protein 28 | [
"Q9NVF7"
] | 1 | 224114111-224162047 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA003289"
] | [
"CENP-30",
"Fbx28",
"FLJ10766",
"KIAA0483"
] | [
"Disease related genes",
"Human disease related genes",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Ubl conjugation pathway"
] | [] | [
"Disease variant",
"Epilepsy",
"Intellectual disability"
] | [
"Nucleoplasm"
] | [
"Focal adhesion sites"
] | [] | [] | Supported | Approved | null | 65 | null | null | Cluster 42: Non-specific - Vesicular transport | Cluster 34: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 7: Non-specific - Transcription | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Chromophobe"
] | [
"Kidney Chromophobe",
"Kidney Renal Clear Cell Carcinoma"
] | 8,334 | 4 |
ENSG00000143761 | ARF1 | ADP ribosylation factor 1 | [
"P84077"
] | 1 | 228082708-228099212 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB007742"
] | [] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [
"Hydrolase"
] | [
"Disease variant"
] | [
"Cytosol"
] | [
"Plasma membrane"
] | [] | [] | Approved | Uncertain | null | 35 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 14: Neurons - Synaptic function | Cluster 45: Non-specific - Nuclear processes | Cluster 47: Platelets - Hemostasis | Cluster 24: Non-specific - Transcription | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 8,335 | 9 |
ENSG00000143768 | LEFTY2 | Left-right determination factor 2 | [
"O00292"
] | 1 | 225936598-225941383 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB025801",
"HPA047883",
"HPA056210"
] | [
"EBAF",
"LEFTA",
"LEFTYA",
"TGFB4"
] | [
"Disease related genes",
"Predicted secreted proteins"
] | [] | [
"Cytokine",
"Developmental protein",
"Growth factor"
] | [
"Disease variant",
"Heterotaxy"
] | [] | [] | [
"Secreted in other tissues"
] | [
"Cytokine"
] | null | Approved | null | null | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 51: Myeloma - Immunoglobulins | Cluster 108: Fibroblasts - ECM organization | Cluster 75: Ovary - Mixed function | Tissue enhanced | Detected in many | null | Group enriched | Detected in some | 13 | Cancer enriched | Detected in many | 11 | Cell type enhanced | Detected in some | null | Not detected in immune cells | Not detected | null | 0 | 0 | 0 | [] | [] | [] | 8,336 | 8 |
ENSG00000143771 | CNIH4 | Cornichon family AMPA receptor auxiliary protein 4 | [
"Q9P003"
] | 1 | 224356858-224379459 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA044268"
] | [
"HSPC163"
] | [
"Predicted membrane proteins"
] | [
"ER-Golgi transport",
"Protein transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 6 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 45: Non-specific - Mixed function | Cluster 3: Rhabdoid - Membrane components | Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier | Cluster 63: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | [
"Head and Neck Squamous Cell Carcinoma"
] | 8,337 | 4 |
ENSG00000143772 | ITPKB | Inositol-trisphosphate 3-kinase B | [
"P27987"
] | 1 | 226631690-226739323 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA030273",
"HPA072923"
] | [
"IP3-3KB",
"IP3KB"
] | [
"Cancer-related genes",
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Calmodulin-binding",
"Kinase",
"Transferase"
] | [
"Cancer-related genes"
] | [
"Nucleoplasm"
] | [] | [] | [] | Approved | Enhanced | null | 9 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 19: Astrocytes - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 101: Choroid plexus epithelial cells - Ion transport | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in many | null | Cancer enhanced | Detected in many | null | Cancer enhanced | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,338 | 6 |
ENSG00000143774 | GUK1 | Guanylate kinase 1 | [
"Q16774"
] | 1 | 228139962-228148984 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA048587"
] | [] | [
"Enzymes",
"Essential proteins",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Transferase"
] | [
"Disease variant"
] | [
"Plasma membrane"
] | [
"Golgi apparatus"
] | [] | [] | Approved | Approved | null | 1 | null | null | Cluster 45: Eosinophils - Unknown function | Cluster 51: Neurons - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 85: Squamous epithelial cells - Keratinization | Cluster 78: Brain - Neuronal signaling | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,339 | 1 |
ENSG00000143776 | CDC42BPA | CDC42 binding protein kinase alpha | [
"Q5VT25"
] | 1 | 226989865-227318492 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB070414",
"HPA071252"
] | [
"FLJ23347",
"KIAA0451",
"MRCK",
"MRCKA",
"PK428"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Kinase",
"Serine/threonine-protein kinase",
"Transferase"
] | [] | [
"Plasma membrane",
"Cytosol"
] | [] | [] | [] | Approved | Approved | null | 22 | null | null | null | Cluster 34: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in all | null | Not detected in immune cells | Not detected | null | 1 | 2 | 0 | [
"Kidney Renal Clear Cell Carcinoma"
] | [] | [
"Kidney Renal Clear Cell Carcinoma"
] | 8,340 | 4 |
ENSG00000143786 | CNIH3 | Cornichon family AMPA receptor auxiliary protein 3 | [
"Q8TBE1"
] | 1 | 224434660-224740554 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"CNIH-3",
"FLJ38993"
] | [
"Predicted membrane proteins",
"Transporters"
] | [] | [] | [] | [] | [] | [] | [] | null | null | null | 23 | null | null | null | Cluster 51: Neurons - Mixed function | Cluster 72: Neuronal - Signal transduction | Cluster 91: Pituicytes/FSC - Homeostasis & neuron support | Cluster 73: Brain - Neuronal signaling | Group enriched | Detected in some | 4 | Cancer enhanced | Detected in many | null | Group enriched | Detected in many | 6 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Lung Adenocarcinoma"
] | [
"Lung Adenocarcinoma"
] | 8,341 | 9 |
ENSG00000143793 | C1orf35 | Chromosome 1 open reading frame 35 | [
"Q9BU76"
] | 1 | 228100726-228105411 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA046175"
] | [
"MGC4174",
"MMTAG2"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Nuclear speckles",
"Plasma membrane"
] | [
"Cytosol"
] | [] | [] | Approved | Approved | null | 52 | null | null | Cluster 29: Non-specific - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 65: Non-specific - Cell growth & division | Cluster 54: Non-specific - Ribosome | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cell type specificity | Detected in many | null | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | [
"Ovary Serous Cystadenocarcinoma",
"Pancreatic Adenocarcinoma"
] | 8,342 | 3 |
ENSG00000143797 | MBOAT2 | Membrane bound O-acyltransferase domain containing 2 | [
"Q6ZWT7"
] | 2 | 8852690-9003709 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA014836"
] | [
"FLJ14415",
"FLJ90298",
"LPLAT13",
"OACT2"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted membrane proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Acyltransferase",
"Transferase"
] | [] | [
"Vesicles"
] | [] | [] | [] | Approved | Uncertain | null | null | null | null | Cluster 35: Neutrophils - Protein binding | Cluster 21: Non-specific - Metabolism | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 37: Neutrophil progenitors - Granulopoiesis | Cluster 73: Brain - Neuronal signaling | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Group enriched | Detected in some | 7 | 3 | 0 | 3 | [] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Lung Adenocarcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Colon Adenocarcinoma",
"Lung Adenocarcinoma"
] | 8,343 | 4 |
ENSG00000143799 | PARP1 | Poly(ADP-ribose) polymerase 1 | [
"P09874"
] | 1 | 226360210-226408154 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB000147",
"CAB003839",
"CAB003840",
"HPA045168",
"CAB075726",
"CAB075727",
"CAB080368"
] | [
"ADPRT",
"ARTD1",
"PARP",
"PARS",
"Poly-PARP",
"PPOL"
] | [
"Cancer-related genes",
"Enzymes",
"FDA approved drug targets",
"Metabolic proteins",
"Plasma proteins",
"Predicted intracellular proteins"
] | [
"Apoptosis",
"DNA damage",
"DNA repair",
"Immunity",
"Innate immunity",
"Transcription",
"Transcription regulation"
] | [
"Allosteric enzyme",
"DNA-binding",
"Glycosyltransferase",
"Nucleotidyltransferase",
"Transferase"
] | [
"Cancer-related genes",
"FDA approved drug targets"
] | [
"Nucleoplasm"
] | [
"Nucleoli",
"Nucleoli fibrillar center",
"Nuclear bodies"
] | [] | [] | Enhanced | Supported | Supported | 548 | null | null | Cluster 14: Non-specific - Unknown function | Cluster 28: Oligodendrocytes - Mixed function | Cluster 6: Leukemia - Signal transduction | Cluster 63: Cytotrophoblasts - Basic cellular functions | Cluster 18: Lymphoid tissue - Immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in all | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,344 | 1 |
ENSG00000143801 | PSEN2 | Presenilin 2 | [
"P49810"
] | 1 | 226870184-226927726 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"AD3L",
"AD4",
"PS2",
"STM2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Potential drug targets",
"Predicted membrane proteins",
"Transporters"
] | [
"Notch signaling pathway"
] | [
"Hydrolase",
"Protease"
] | [
"Alzheimer disease",
"Amyloidosis",
"Cardiomyopathy",
"Disease variant",
"Neurodegeneration"
] | [] | [] | [] | [] | null | null | null | 67 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 23: Choroid plexus - Mixed function | Cluster 9: Skin cancer - Melanin biosynthesis | Cluster 50: Renal epithelial cells - Ion transport and pH regulation | Cluster 70: Non-specific - Protein processing | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in some | null | Low immune cell specificity | Detected in many | null | 0 | 0 | 0 | [] | [] | [] | 8,345 | 2 |
ENSG00000143811 | PYCR2 | Pyrroline-5-carboxylate reductase 2 | [
"Q96C36"
] | 1 | 225919877-225924340 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [
"HPA056873"
] | [
"P5CR2"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Amino-acid biosynthesis",
"Proline biosynthesis"
] | [
"Oxidoreductase"
] | [
"Disease variant",
"Leukodystrophy"
] | [
"Mitochondria"
] | [] | [] | [] | Approved | Approved | null | 40 | null | null | Cluster 3: Non-specific - Nuclear processes | Cluster 22: Non-specific - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 98: Neurons - Neurotransmission & signaling | Cluster 68: Non-specific - Basic cellular processes | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 0 | 0 | 0 | [] | [] | [] | 8,346 | 5 |
ENSG00000143815 | LBR | Lamin B receptor | [
"Q14739"
] | 1 | 225401502-225428925 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA049840",
"HPA062236"
] | [
"DHCR14B",
"TDRD18"
] | [
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Plasma proteins",
"Potential drug targets",
"Predicted intracellular proteins",
"Predicted membrane proteins"
] | [
"Cholesterol biosynthesis",
"Cholesterol metabolism",
"Lipid biosynthesis",
"Lipid metabolism",
"Steroid biosynthesis",
"Steroid metabolism",
"Sterol biosynthesis",
"Sterol metabolism"
] | [
"DNA-binding",
"Oxidoreductase",
"Receptor"
] | [
"Disease variant",
"Dwarfism"
] | [
"Nuclear membrane"
] | [
"Nucleoli fibrillar center"
] | [] | [] | Supported | Enhanced | null | 83 | null | Yes | Cluster 35: Neutrophils - Protein binding | Cluster 28: Oligodendrocytes - Mixed function | Cluster 45: Non-specific - Nuclear processes | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 51: Lymphoid tissue - Adaptive immune response | Low tissue specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Group enriched | Detected in many | 4 | Low immune cell specificity | Detected in all | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Liver Hepatocellular Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,347 | 3 |
ENSG00000143816 | WNT9A | Wnt family member 9A | [
"O14904"
] | 1 | 227918656-227947932 | Evidence at protein level | Evidence at transcript level | Evidence at protein level | Evidence at protein level | [] | [
"WNT14"
] | [
"Plasma proteins",
"Predicted secreted proteins"
] | [
"Wnt signaling pathway"
] | [
"Developmental protein"
] | [] | [] | [] | [
"Secreted to extracellular matrix"
] | [
"Developmental protein"
] | null | null | null | 1 | null | null | null | Cluster 44: Non-specific - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 100: Stratified epithelial cells - Barrier functions | Cluster 24: Non-specific - Transcription | Tissue enhanced | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Bladder Urothelial Carcinoma"
] | [
"Ovary Serous Cystadenocarcinoma"
] | [
"Bladder Urothelial Carcinoma",
"Ovary Serous Cystadenocarcinoma"
] | 8,348 | 2 |
ENSG00000143819 | EPHX1 | Epoxide hydrolase 1 | [
"P07099"
] | 1 | 225810124-225845563 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA020593",
"HPA048847"
] | [
"EPHX"
] | [
"Cancer-related genes",
"Disease related genes",
"Enzymes",
"Human disease related genes",
"Metabolic proteins",
"Potential drug targets",
"Predicted intracellular proteins"
] | [
"Aromatic hydrocarbons catabolism",
"Detoxification",
"Lipid metabolism"
] | [
"Hydrolase"
] | [
"Cancer-related genes"
] | [] | [] | [] | [] | null | Enhanced | null | 21 | null | null | Cluster 10: Non-specific - Membrane trafficking | Cluster 42: Choroid plexus - Mitochondria | Cluster 7: Liver cancer - Metabolism | Cluster 18: Adrenal cortex cells - Steroidogensis | Cluster 76: Non-specific - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Cancer enriched | Detected in all | 5 | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 4 | 2 | 3 | [
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | [
"Breast Invasive Carcinoma"
] | [
"Breast Invasive Carcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma",
"Lung Adenocarcinoma"
] | 8,349 | 8 |
ENSG00000143839 | REN | Renin | [
"P00797"
] | 1 | 204154819-204190324 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA005131"
] | [] | [
"Candidate cardiovascular disease genes",
"Disease related genes",
"Enzymes",
"FDA approved drug targets",
"Human disease related genes",
"Predicted intracellular proteins",
"Predicted secreted proteins"
] | [] | [
"Aspartyl protease",
"Hydrolase",
"Protease"
] | [
"Disease variant",
"FDA approved drug targets"
] | [] | [] | [
"Secreted to blood"
] | [
"Enzyme"
] | null | Approved | null | 5 | null | null | null | Cluster 36: Choroid plexus - Mixed function | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 108: Fibroblasts - ECM organization | Cluster 72: Kidney - Transmembrane transport | Tissue enriched | Detected in some | 9 | Group enriched | Detected in some | 5 | Cancer enriched | Detected in many | 9 | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 2 | 0 | 2 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Kidney Renal Papillary Cell Carcinoma"
] | [
"Kidney Renal Clear Cell Carcinoma",
"Kidney Renal Papillary Cell Carcinoma"
] | 8,350 | 7 |
ENSG00000143842 | SOX13 | SRY-box transcription factor 13 | [
"Q9UN79"
] | 1 | 204073115-204127743 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA051790",
"HPA054843"
] | [
"ICA12",
"MGC117216",
"Sox-13"
] | [
"Disease related genes",
"Plasma proteins",
"Predicted intracellular proteins",
"Transcription factors"
] | [
"Differentiation",
"Transcription",
"Transcription regulation"
] | [
"DNA-binding",
"Repressor"
] | [] | [
"Nucleoplasm"
] | [] | [] | [] | Enhanced | null | null | 13 | null | null | Cluster 15: NK-cells - Unknown function | Cluster 19: Astrocytes - Mixed function | Cluster 27: Breast cancer - Unknown function | Cluster 105: Non-specific - Mixed function | Cluster 74: Non-specific - Signal transduction | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Immune cell enhanced | Detected in single | null | 3 | 0 | 3 | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Colon Adenocarcinoma"
] | [
"Colon Adenocarcinoma",
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma"
] | 8,351 | 6 |
ENSG00000143845 | ETNK2 | Ethanolamine kinase 2 | [
"Q9NVF9"
] | 1 | 204131062-204152044 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA057167"
] | [
"EKI2",
"FLJ10761"
] | [
"Enzymes",
"Metabolic proteins",
"Predicted intracellular proteins"
] | [
"Lipid biosynthesis",
"Lipid metabolism",
"Phospholipid biosynthesis",
"Phospholipid metabolism"
] | [
"Kinase",
"Transferase"
] | [] | [] | [] | [] | [] | null | Enhanced | null | 7 | null | null | Cluster 1: T-cells - Unknown function | Cluster 42: Choroid plexus - Mitochondria | Cluster 27: Breast cancer - Unknown function | Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization | Cluster 16: Liver & Kidney - Metabolism | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enriched | Detected in many | 4 | Low immune cell specificity | Detected in some | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Glioblastoma Multiforme",
"Pancreatic Adenocarcinoma"
] | [
"Glioblastoma Multiforme",
"Kidney Renal Clear Cell Carcinoma",
"Pancreatic Adenocarcinoma"
] | 8,352 | 2 |
ENSG00000143847 | PPFIA4 | PTPRF interacting protein alpha 4 | [
"O75335"
] | 1 | 203026491-203078740 | Evidence at protein level | Evidence at protein level | Evidence at transcript level | Evidence at protein level | [
"HPA053419",
"HPA054132"
] | [] | [
"Plasma proteins",
"Predicted intracellular proteins"
] | [] | [] | [] | [] | [] | [] | [] | null | Enhanced | null | 3 | null | null | Cluster 25: Non-specific - Unknown function | Cluster 37: Neurons - Mixed function | Cluster 15: Kidney cancer - Membrane components | Cluster 2: Cerebellar granular cells - Neuronal signaling | Cluster 27: Cerebellum - Synaptic function | Tissue enriched | Detected in many | 6 | Low cancer specificity | Detected in many | null | Cancer enhanced | Detected in many | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 1 | 0 | 1 | [] | [
"Pancreatic Adenocarcinoma"
] | [
"Pancreatic Adenocarcinoma"
] | 8,353 | 7 |
ENSG00000143850 | PLEKHA6 | Pleckstrin homology domain containing A6 | [
"Q9Y2H5"
] | 1 | 204218853-204377665 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA028152",
"HPA028157",
"HPA054311"
] | [
"KIAA0969",
"PEPP3"
] | [
"Predicted intracellular proteins"
] | [] | [] | [] | [
"Cell Junctions"
] | [
"Vesicles"
] | [] | [] | Approved | Enhanced | null | 3 | null | null | null | Cluster 40: Astrocytes - Astrocyte-neuron interactions | Cluster 53: Squamous epithelial cells - Keratinization | Cluster 88: Proximal tubular cells - Transmembrane transport | Cluster 64: Non-specific - Transcription | Low tissue specificity | Detected in many | null | Low cancer specificity | Detected in many | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Not detected in immune cells | Not detected | null | 3 | 0 | 3 | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma"
] | [
"Lung Squamous Cell Carcinoma"
] | [
"Colon Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Lung Squamous Cell Carcinoma"
] | 8,354 | 2 |
ENSG00000143851 | PTPN7 | Protein tyrosine phosphatase non-receptor type 7 | [
"P35236"
] | 1 | 202147013-202161588 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"CAB009530",
"HPA019118"
] | [
"HEPTP",
"LC-PTP"
] | [
"Enzymes",
"Predicted intracellular proteins"
] | [] | [
"Hydrolase",
"Protein phosphatase"
] | [] | [
"Cytosol"
] | [
"Microtubules",
"Mitotic spindle"
] | [] | [] | Supported | Approved | null | 9 | Yes | null | Cluster 5: Non-specific - Cell proliferation | Cluster 33: Neurons - Mixed function | Cluster 49: HMC-1 - Innate immune response | Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity | Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation | Group enriched | Detected in many | 6 | Group enriched | Detected in some | 32 | Low cancer specificity | Detected in many | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in all | null | 1 | 0 | 1 | [
"Head and Neck Squamous Cell Carcinoma"
] | [] | [
"Head and Neck Squamous Cell Carcinoma"
] | 8,355 | 6 |
ENSG00000143862 | ARL8A | ADP ribosylation factor like GTPase 8A | [
"Q96BM9"
] | 1 | 202133404-202144743 | Evidence at protein level | Evidence at protein level | Evidence at protein level | Evidence at protein level | [
"HPA038759",
"HPA040515",
"HPA045924"
] | [
"ARL10B",
"FLJ45195",
"Gie2"
] | [
"Predicted intracellular proteins"
] | [
"Cell cycle",
"Cell division",
"Chromosome partition",
"Mitosis",
"Protein transport",
"Transport"
] | [] | [] | [] | [] | [] | [] | null | Approved | null | 39 | null | null | Cluster 22: Eosinophils - Transcription | Cluster 30: White matter - Myelination | Cluster 45: Non-specific - Nuclear processes | Cluster 48: Neutrophils - Phagocytosis & degranulation | Cluster 3: Oligodendrocytes - Myelination | Tissue enhanced | Detected in all | null | Low cancer specificity | Detected in all | null | Low cancer specificity | Detected in all | null | Cell type enhanced | Detected in many | null | Low immune cell specificity | Detected in many | null | 3 | 0 | 3 | [
"Kidney Renal Clear Cell Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Liver Hepatocellular Carcinoma"
] | [
"Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma",
"Kidney Renal Clear Cell Carcinoma",
"Liver Hepatocellular Carcinoma"
] | 8,357 | 8 |
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