ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000141642
ELAC1
ElaC ribonuclease Z 1
[ "Q9H777" ]
18
50967991-50988121
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040867", "HPA066483" ]
[ "D29" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "tRNA processing" ]
[ "Endonuclease", "Hydrolase", "Nuclease" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
null
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 13: Non-specific - Mixed function
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
8,032
8
ENSG00000141644
MBD1
Methyl-CpG binding domain protein 1
[ "Q9UIS9" ]
18
50266882-50281774
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB009017", "CAB036003", "HPA068850" ]
[ "CXXC3", "PCM1" ]
[ "Cancer-related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm", "Vesicles" ]
[]
[]
[]
Approved
Approved
null
30
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
8,033
6
ENSG00000141646
SMAD4
SMAD family member 4
[ "Q13485" ]
18
51028394-51085045
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019154", "CAB080136" ]
[ "DPC4", "MADH4" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Cancer-related genes", "Disease variant" ]
[ "Nucleoplasm", "Centrosome", "Basal body" ]
[ "Vesicles", "Primary cilium tip", "Cytosol" ]
[]
[]
Supported
Approved
null
183
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 15: Non-specific - Transcription
Cluster 13: Non-specific - Mixed function
Cluster 22: Non-specific - Basic cellular functions
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,034
2
ENSG00000141655
TNFRSF11A
TNF receptor superfamily member 11a
[ "Q9Y6Q6" ]
18
62325287-62391288
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB010391", "HPA047976" ]
[ "CD265", "FEO", "LOH18CR1", "ODFR", "PDB2", "RANK", "TRANCE-R" ]
[ "CD markers", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[ "Deafness", "Disease variant", "Osteopetrosis" ]
[ "Plasma membrane" ]
[ "Cytosol" ]
[ "Intracellular and membrane" ]
[ "Receptor" ]
Supported
Approved
null
9
null
null
Cluster 15: NK-cells - Unknown function
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 50: Lymphoma - Unknown function
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
8
3
0
3
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
8,035
4
ENSG00000141664
ZCCHC2
Zinc finger CCHC-type containing 2
[ "Q9C0B9" ]
18
62523025-62587709
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040711", "HPA040943" ]
[ "C18orf49", "FLJ20222", "FLJ20281", "KIAA1744" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoli" ]
[ "Nucleoplasm", "Nucleoli rim", "Cytosol" ]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 20: Non-specific - DNA binding
Cluster 11: White matter - Signal transduction
Cluster 13: Non-specific - Mixed function
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 45: Liver - Metabolism & Coagulation
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in single
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
8,036
8
ENSG00000141665
FBXO15
F-box protein 15
[ "Q8NCQ5" ]
18
74073353-74147843
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FBX15", "MGC39671" ]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[]
[]
[]
[]
null
null
null
6
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 46: Brainstem - Mixed function
Cluster 70: DU4475 - Unknown function
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,037
5
ENSG00000141668
CBLN2
Cerebellin 2 precursor
[ "Q8IUK8" ]
18
72536680-72638521
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA056335" ]
[]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[ "Cytosol", "Flagellar centriole", "Mid piece", "Principal piece" ]
[ "Perinuclear theca", "Calyx" ]
[ "Secreted in brain" ]
[ "No annotated function" ]
Approved
null
null
null
null
null
null
Cluster 14: Neurons - Synaptic function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 73: Brain - Neuronal signaling
Tissue enriched
Detected in some
8
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
7
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Uterine Corpus Endometrial Carcinoma" ]
[ "Uterine Corpus Endometrial Carcinoma" ]
8,038
8
ENSG00000141682
PMAIP1
Phorbol-12-myristate-13-acetate-induced protein 1
[ "Q13794" ]
18
59899996-59904305
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051063" ]
[ "APR", "NOXA" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Uncertain
Uncertain
null
12
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 47: Endothelial cells - Vasculature
Cluster 13: Non-specific - Mixed function
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
5
0
5
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
8,039
3
ENSG00000141696
P3H4
Prolyl 3-hydroxylase family member 4 (inactive)
[ "Q92791" ]
17
41801947-41812604
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA022520" ]
[ "LEPREL4", "NO55", "SC65" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Endoplasmic reticulum", "Vesicles" ]
[]
[ "Intracellular and membrane" ]
[ "No annotated function" ]
Approved
null
null
26
null
null
Cluster 24: Non-specific - Transcription
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
5
2
4
0
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
8,040
7
ENSG00000141699
RETREG3
Reticulophagy regulator family member 3
[ "Q86VR2" ]
17
42579513-42610623
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016492" ]
[ "DKFZp686B1036", "FAM134C", "FLJ33806" ]
[ "Predicted membrane proteins" ]
[ "Autophagy" ]
[]
[]
[ "Nucleoplasm", "Nuclear membrane" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
149
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 38: Sub-cortical - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 7: Non-specific - Transcription
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma" ]
8,042
2
ENSG00000141736
ERBB2
Erb-b2 receptor tyrosine kinase 2
[ "P04626" ]
17
39687914-39730426
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000043", "HPA001060", "HPA001338", "HPA001383", "HPA007983", "CAB020416", "CAB062555" ]
[ "c-ERB-2", "c-ERB2", "CD340", "HER-2", "HER2", "MLN-19", "NEU", "NGL", "p185(erbB2)" ]
[ "Cancer-related genes", "CD markers", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "Kinase", "Receptor", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Enhanced
Enhanced
null
202
null
null
Cluster 24: Non-specific - Transcription
Cluster 39: Astrocytes - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Group enriched
Detected in all
5
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
8,043
7
ENSG00000141738
GRB7
Growth factor receptor bound protein 7
[ "Q14451" ]
17
39737927-39747291
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005226", "HPA057084", "CAB073538" ]
[]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[]
[ "Repressor", "RNA-binding" ]
[ "Cancer-related genes" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
41
null
null
null
Cluster 5: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 26: Keratinocytes - Keratinization
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
8,044
4
ENSG00000141741
MIEN1
Migration and invasion enhancer 1
[ "Q9BRT3" ]
17
39728496-39730532
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA056650", "HPA061344" ]
[ "C17orf37", "C35", "MGC14832", "ORB3", "Rdx12", "XTP4" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
11
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 27: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
8,045
7
ENSG00000141744
PNMT
Phenylethanolamine N-methyltransferase
[ "P11086" ]
17
39667981-39670475
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017029", "HPA043412", "HPA051005" ]
[ "PENT" ]
[ "Cancer-related genes", "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Catecholamine biosynthesis" ]
[ "Methyltransferase", "Transferase" ]
[ "Cancer-related genes" ]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 70: DU4475 - Unknown function
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in some
5
Group enriched
Detected in many
4
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,046
9
ENSG00000141748
ARL5C
ADP ribosylation factor like GTPase 5C
[ "A6NH57" ]
17
39156894-39167484
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Evidence at protein level
[ "HPA069849" ]
[ "ARL12" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 80: Thymus - Adaptive immune response
Tissue enriched
Detected in single
5
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,047
8
ENSG00000141750
STAC2
SH3 and cysteine rich domain 2
[ "Q6ZMT1" ]
17
39210541-39225945
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA076925" ]
[ "24b2" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
null
null
3
null
null
null
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 27: Breast cancer - Unknown function
Cluster 11: Muller glia cells - Retinal homeostasis
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
4
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
8,048
5
ENSG00000141753
IGFBP4
Insulin like growth factor binding protein 4
[ "P22692" ]
17
40443450-40457725
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA066240" ]
[ "BP-4", "HT29-IGFBP", "IBP4", "IGFBP-4" ]
[ "Plasma proteins", "Predicted secreted proteins" ]
[]
[ "Growth factor binding" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Other" ]
null
Supported
null
27
null
null
Cluster 15: NK-cells - Unknown function
Cluster 42: Choroid plexus - Mitochondria
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
4
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Skin Cutaneous Melanoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Skin Cutaneous Melanoma" ]
8,049
7
ENSG00000141756
FKBP10
FKBP prolyl isomerase 10
[ "Q96AY3" ]
17
41812680-41823213
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA013808", "HPA051171", "HPA057021" ]
[ "FKBP6", "FKBP65", "FLJ20683", "FLJ22041", "FLJ23833", "hFKBP65" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Isomerase", "Rotamase" ]
[ "Disease variant", "Osteogenesis imperfecta" ]
[ "Golgi apparatus" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Enhanced
null
10
null
null
null
Cluster 39: Astrocytes - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
5
2
4
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Thyroid Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma", "Thyroid Carcinoma" ]
8,050
5
ENSG00000141759
TXNL4A
Thioredoxin like 4A
[ "P83876" ]
18
79970813-80033949
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA076100" ]
[ "DIB1", "DIM1", "HsT161", "SNRNP15", "TXNL4", "U5-15kD" ]
[ "Disease related genes", "Essential proteins", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle", "Cell division", "Mitosis", "mRNA processing", "mRNA splicing" ]
[]
[ "Deafness" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
null
null
51
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 27: Non-specific - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 97: Non-specific - Cellular respiration
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
8,051
8
ENSG00000141837
CACNA1A
Calcium voltage-gated channel subunit alpha1 A
[ "O00555" ]
19
13206442-13633025
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA064258", "HPA068138", "HPA071902" ]
[ "APCA", "CACNL1A4", "Cav2.1", "EA2", "FHM", "HPCA", "MHP", "MHP1", "SCA6" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[ "Calcium channel", "Ion channel", "Voltage-gated channel" ]
[ "Disease variant", "Epilepsy", "FDA approved drug targets", "Neurodegeneration", "Spinocerebellar ataxia" ]
[ "Endoplasmic reticulum" ]
[]
[]
[]
Uncertain
Enhanced
Supported
41
null
null
null
Cluster 2: Neurons - Nucleosome
Cluster 10: Ciliated cells - Ion channel activity
Cluster 96: Enteroendocrine cells - Neuropeptide signaling
Cluster 71: Cerebellum - Nervous system development
Tissue enriched
Detected in many
43
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
[]
[ "Glioblastoma Multiforme", "Pancreatic Adenocarcinoma" ]
8,052
7
ENSG00000141854
MISP3
MISP family member 3
[ "Q96FF7" ]
19
14072536-14075062
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA042225" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 68: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Not detected
Not detected
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in single
null
3
0
3
[ "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma", "Stomach Adenocarcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Pancreatic Adenocarcinoma", "Stomach Adenocarcinoma" ]
8,053
1
ENSG00000141858
SAMD1
Sterile alpha motif domain containing 1
[]
19
14087851-14091036
Evidence at transcript level
Evidence at transcript level
null
null
[ "HPA049059", "HPA075278" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Mitotic chromosome" ]
[ "Intracellular and membrane" ]
[]
Approved
Uncertain
null
2
Yes
null
Cluster 33: Non-specific - ATP binding
Cluster 19: Astrocytes - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
8,054
5
ENSG00000141867
BRD4
Bromodomain containing 4
[ "O60885" ]
19
15235519-15332545
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015055", "HPA061646", "CAB068177", "CAB068178" ]
[ "CAP", "HUNK1", "HUNKI", "MCAP" ]
[ "Cancer-related genes", "Disease related genes", "Essential proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator" ]
[ "Cancer-related genes", "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Mitotic chromosome" ]
[]
[]
Enhanced
Supported
null
502
Yes
null
Cluster 20: Non-specific - DNA binding
Cluster 4: Non-specific - mRNA splicing & Cell cycle
Cluster 23: Non-specific - Transcription
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
8,055
3
ENSG00000141873
SLC39A3
Solute carrier family 39 member 3
[ "Q9BRY0" ]
19
2732204-2740028
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042139", "HPA058526" ]
[ "ZIP3" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Transport", "Zinc transport" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Uncertain
null
11
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 32: Cerebral cortex - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
8,056
2
ENSG00000141905
NFIC
Nuclear factor I C
[ "P08651" ]
19
3314403-3469217
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004300", "CAB004674", "HPA052625", "HPA063560" ]
[ "CTF", "CTF5", "NF-I", "NFI" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "DNA replication", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding" ]
[]
[ "Nucleoplasm", "Nucleoli fibrillar center" ]
[]
[]
[]
Enhanced
Supported
null
136
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 18: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 108: Fibroblasts - ECM organization
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,057
2
ENSG00000141933
TPGS1
Tubulin polyglutamylase complex subunit 1
[ "Q6ZTW0" ]
19
507497-519654
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C19orf20", "GTRGEO22", "PGs1" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein" ]
[]
[]
[]
[]
[]
null
null
null
12
null
null
Cluster 19: Eosinophils - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 97: Non-specific - Cellular respiration
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
8,058
6
ENSG00000141934
PLPP2
Phospholipid phosphatase 2
[ "O43688" ]
19
281040-291403
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA055540", "HPA058428" ]
[ "LPP2", "PAP-2c", "PPAP2C" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[ "Lipid metabolism" ]
[ "Hydrolase" ]
[]
[ "Plasma membrane" ]
[]
[]
[]
Supported
Uncertain
null
6
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 38: Secretory epithelial cells - Exocrine secretion
Cluster 60: Stomach - Digestion
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
0
2
[]
[ "Breast Invasive Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Pancreatic Adenocarcinoma" ]
8,059
9
ENSG00000141946
ZIM3
Zinc finger imprinted 3
[ "Q96PE6" ]
19
57134096-57145202
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA034575" ]
[ "ZNF657" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
1
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 61: BICR 18 - Protein kinases
Cluster 106: Spermatogonia - Spermatogonial differentiation
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,060
1
ENSG00000141956
PRDM15
PR/SET domain 15
[ "P57071" ]
21
41798225-41879482
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024268", "HPA029255", "HPA029256" ]
[ "C21orf83", "ZNF298" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "Developmental protein", "DNA-binding", "Methyltransferase", "Repressor", "Transferase" ]
[]
[ "Nuclear bodies" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Uncertain
null
7
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 51: Neurons - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 44: Plasma cells - Antibody production & secretion
Cluster 34: Lymphoid tissue - Adaptive immune response
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
4
0
4
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Head and Neck Squamous Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
8,061
6
ENSG00000141959
PFKL
Phosphofructokinase, liver type
[ "P17858" ]
21
44300051-44327376
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030047" ]
[]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Glycolysis" ]
[ "Allosteric enzyme", "Kinase", "Transferase" ]
[]
[ "Nucleoli", "Mitochondria" ]
[]
[]
[]
Uncertain
Approved
null
29
null
null
Cluster 33: Non-specific - ATP binding
Cluster 27: Non-specific - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 65: Non-specific - Cell growth & division
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,062
5
ENSG00000141965
FEM1A
Fem-1 homolog A
[ "Q9BSK4" ]
19
4791734-4801273
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016565", "HPA063622" ]
[]
[ "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[]
[]
[ "Nucleoplasm", "Golgi apparatus" ]
[ "Cytosol" ]
[]
[]
Supported
null
null
31
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 15: Non-specific - Transcription
Cluster 23: Non-specific - Transcription
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 30: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in many
11
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Stomach Adenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma", "Stomach Adenocarcinoma" ]
8,063
7
ENSG00000141968
VAV1
Vav guanine nucleotide exchange factor 1
[ "P15498" ]
19
6772708-6857366
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001864", "HPA005925" ]
[ "VAV" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[ "Proto-oncogene" ]
[ "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
50
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in many
null
Group enriched
Detected in many
7
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Skin Cutaneous Melanoma" ]
[]
[ "Skin Cutaneous Melanoma" ]
8,064
7
ENSG00000141971
MVB12A
Multivesicular body subunit 12A
[ "Q96EY5" ]
19
17405722-17433724
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041885", "HPA042231" ]
[ "FAM125A", "FLJ32495" ]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Supported
Approved
null
27
null
No
Cluster 10: Non-specific - Membrane trafficking
Cluster 27: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,065
3
ENSG00000141977
CIB3
Calcium and integrin binding family member 3
[ "Q96Q77" ]
19
16161368-16173525
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043553", "HPA043995" ]
[ "KIP3" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
50
null
null
Cluster 22: Eosinophils - Transcription
null
Cluster 49: HMC-1 - Innate immune response
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 44: Bone marrow - Nuclear processes
Tissue enhanced
Detected in single
null
Not detected
Not detected
null
Cancer enriched
Detected in single
9
Cell type enriched
Detected in some
4
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
8,066
4
ENSG00000141985
SH3GL1
SH3 domain containing GRB2 like 1, endophilin A2
[ "Q99961" ]
19
4360370-4400547
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021485" ]
[ "CNSA1", "EEN", "MGC111371", "SH3D2B", "SH3P8" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Endocytosis" ]
[]
[ "Cancer-related genes", "Proto-oncogene" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
49
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 34: Non-specific - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 84: Apical squamous epithelium - Cornification
Cluster 81: Squamous epithelium - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in many
null
3
0
3
[ "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Rectum Adenocarcinoma" ]
8,067
2
ENSG00000141994
DUS3L
Dihydrouridine synthase 3 like
[ "Q96G46" ]
19
5784832-5791225
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041854", "HPA041944", "HPA062846" ]
[ "DUS3", "FLJ13896" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "mRNA processing", "tRNA processing" ]
[ "Oxidoreductase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Uncertain
null
5
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 11: White matter - Signal transduction
Cluster 23: Non-specific - Transcription
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
8,068
1
ENSG00000142002
DPP9
Dipeptidyl peptidase 9
[ "Q86TI2" ]
19
4674341-4724673
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA036059" ]
[]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Aminopeptidase", "Hydrolase", "Protease", "Serine protease" ]
[ "Disease variant" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
5
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 38: Sub-cortical - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]
8,069
5
ENSG00000142025
DMRTC2
DMRT like family C2
[ "Q8IXT2" ]
19
41844743-41852333
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA045016" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Sexual differentiation", "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
null
Cluster 4: Non-specific - Transcription
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 23: Testis - Spermatogenesis
Tissue enriched
Detected in single
108
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
8
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,070
3
ENSG00000142039
CCDC97
Coiled-coil domain containing 97
[ "Q96F63" ]
19
41310172-41324873
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043320", "HPA043572" ]
[ "FLJ40267", "MGC20255" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
Supported
Enhanced
null
43
null
null
Cluster 14: Non-specific - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 20: Non-specific - Transcription regulation
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
8,071
7
ENSG00000142046
TMEM91
Transmembrane protein 91
[ "Q6ZNR0" ]
19
41350911-41384083
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA053240" ]
[ "DSPC3", "FLJ27310", "IFITMD6" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 1: Neuronal - Visual perception
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 2: Non-specific - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enriched
Detected in all
5
Group enriched
Detected in many
4
Immune cell enhanced
Detected in many
null
2
0
2
[]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
8,072
5
ENSG00000142065
ZFP14
ZFP14 zinc finger protein
[ "Q9HCL3" ]
19
36334453-36379201
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030637" ]
[ "KIAA1559", "ZNF531" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 24: Non-specific - Transcription
Cluster 50: Non-specific - Nucleic acid binding
Cluster 4: Non-specific - Transcription
Cluster 7: Non-specific - Transcription
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
8,073
5
ENSG00000142082
SIRT3
Sirtuin 3
[ "Q9NTG7" ]
11
215030-236931
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB037142" ]
[ "SIR2L3" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
Supported
null
32
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 23: Choroid plexus - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 7: Non-specific - Transcription
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
8,074
6
ENSG00000142102
PGGHG
Protein-glucosylgalactosylhydroxylysine glucosidase
[ "Q32M88" ]
11
289126-296107
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039383", "HPA058829" ]
[ "ATHL1", "FLJ22635" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Glycosidase", "Hydrolase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Enhanced
Uncertain
null
1
null
Yes
Cluster 15: NK-cells - Unknown function
Cluster 12: Non-specific - Vasculature
Cluster 59: Leukemia - T-cell receptor
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 8: Pancreas - Proteolysis
Tissue enriched
Detected in many
4
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
0
4
[ "Kidney Renal Papillary Cell Carcinoma", "Stomach Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Stomach Adenocarcinoma" ]
8,076
1
ENSG00000142149
HUNK
Hormonally up-regulated Neu-associated kinase
[ "P57058" ]
21
31873020-32044633
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA027232", "HPA027295", "HPA027372" ]
[]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm", "Plasma membrane" ]
[]
[]
[]
Approved
Approved
null
5
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling
Cluster 8: Pancreas - Proteolysis
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,077
7
ENSG00000142156
COL6A1
Collagen type VI alpha 1 chain
[ "P12109" ]
21
45981770-46005050
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019142", "HPA029401" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Cell adhesion" ]
[]
[ "Cancer-related genes", "Congenital muscular dystrophy", "Disease variant" ]
[ "Cytosol" ]
[]
[ "Secreted to extracellular matrix" ]
[ "Cell adhesion" ]
Approved
Enhanced
null
25
null
null
null
Cluster 50: Non-specific - Nucleic acid binding
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Glioblastoma Multiforme", "Thyroid Carcinoma" ]
[ "Glioblastoma Multiforme", "Thyroid Carcinoma" ]
8,078
8
ENSG00000142168
SOD1
Superoxide dismutase 1
[ "P00441" ]
21
31659666-31668931
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001401", "CAB008670" ]
[ "ALS", "ALS1", "IPOA" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Antioxidant", "Oxidoreductase" ]
[ "Amyotrophic lateral sclerosis", "Cancer-related genes", "Disease variant", "Neurodegeneration" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Enhanced
Enhanced
null
119
null
null
Cluster 9: T-regs - Cell cycle regulation
Cluster 27: Non-specific - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
8,080
8
ENSG00000142173
COL6A2
Collagen type VI alpha 2 chain
[ "P12110" ]
21
46098112-46132848
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007029", "HPA030920", "HPA038799" ]
[]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Cell adhesion" ]
[]
[ "Congenital muscular dystrophy", "Disease variant" ]
[ "Cytosol" ]
[ "Plasma membrane" ]
[ "Secreted to extracellular matrix" ]
[ "Cell adhesion" ]
Uncertain
Enhanced
null
null
null
null
Cluster 1: T-cells - Unknown function
Cluster 3: Choroid plexus - Cilium
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Group enriched
Detected in some
6
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
8,081
8
ENSG00000142178
SIK1
Salt inducible kinase 1
[ "P57059" ]
21
43414483-43427131
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB023801", "HPA038211", "HPA078064" ]
[ "msk", "SNF1LK" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Biological rhythms", "Cell cycle", "Differentiation" ]
[ "Developmental protein", "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Disease variant", "Epilepsy", "Tumor suppressor" ]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Approved
Approved
null
41
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 7: Liver cancer - Metabolism
Cluster 26: Keratinocytes - Keratinization
Cluster 58: Skin - Keratinization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[]
[ "Lung Squamous Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
8,082
5
ENSG00000142182
DNMT3L
DNA methyltransferase 3 like
[ "Q9UJW3" ]
21
44246339-44262216
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA055234", "HPA066780" ]
[ "MGC1090" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Spermatogenesis" ]
[]
[]
[ "Nuclear speckles" ]
[]
[]
[]
Approved
Approved
null
11
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 34: Testis cancer - Unknown function
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 16: Liver & Kidney - Metabolism
Tissue enhanced
Detected in single
null
Cancer enriched
Detected in single
10
Cancer enriched
Detected in some
45
Group enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,083
7
ENSG00000142186
SCYL1
SCY1 like pseudokinase 1
[ "Q96KG9" ]
11
65525077-65538704
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015015" ]
[ "GKLP", "HT019", "MGC78454", "NKTL", "NTKL", "P105", "TAPK", "TEIF", "TRAP" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "ER-Golgi transport", "Transcription", "Transcription regulation", "Transport" ]
[ "Activator", "DNA-binding" ]
[ "Intellectual disability", "Neurodegeneration", "Spinocerebellar ataxia" ]
[ "Cytosol" ]
[]
[]
[]
Supported
null
null
40
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 32: Cerebral cortex - Mixed function
Cluster 24: Non-specific - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Colon Adenocarcinoma", "Lung Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Lung Adenocarcinoma" ]
8,085
5
ENSG00000142188
TMEM50B
Transmembrane protein 50B
[ "P56557" ]
21
33432485-33479974
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB034199", "HPA068995" ]
[ "C21orf4" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Nucleoli fibrillar center" ]
[]
[]
[]
Approved
Approved
null
18
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 38: Sub-cortical - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 102: Non-specific - Mixed function
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
8,086
2
ENSG00000142192
APP
Amyloid beta precursor protein
[ "P05067" ]
21
25880535-26171128
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000157", "HPA001462" ]
[ "AD1", "alpha-sAPP" ]
[ "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "Transporters" ]
[ "Apoptosis", "Cell adhesion", "Endocytosis", "Notch signaling pathway" ]
[ "Heparin-binding", "Protease inhibitor", "Serine protease inhibitor" ]
[ "Alzheimer disease", "Amyloidosis", "Disease variant", "FDA approved drug targets", "Neurodegeneration" ]
[ "Golgi apparatus" ]
[ "Vesicles" ]
[ "Secreted to blood" ]
[ "Cell adhesion" ]
Supported
Enhanced
null
499
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 27: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 36: Brain & Liver - Signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Immune cell enriched
Detected in many
5
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,087
4
ENSG00000142197
DOP1B
DOP1 leucine zipper like protein B
[ "Q9Y3R5" ]
21
36156782-36294274
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA072065" ]
[ "C21orf5", "DOPEY2", "KIAA0933" ]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Nucleoplasm" ]
[ "Mitochondria" ]
[]
[]
Approved
Enhanced
null
null
Yes
No
Cluster 23: B-cells - Immunoglobulins
Cluster 15: Non-specific - Transcription
Cluster 27: Breast cancer - Unknown function
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 76: Non-specific - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
8,088
1
ENSG00000142207
URB1
URB1 ribosome biogenesis homolog
[ "O60287" ]
21
32311018-32393012
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018334" ]
[ "C21orf108", "KIAA0539", "NPA1" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoli fibrillar center" ]
[]
[]
[]
Supported
Supported
null
20
null
null
Cluster 14: Non-specific - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
8,089
8
ENSG00000142224
IL19
Interleukin 19
[ "Q9UHD0" ]
1
206770764-206842981
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "IL-10C", "IL-19", "MDA1", "NG.1", "ZMDA1" ]
[ "Predicted secreted proteins" ]
[ "Apoptosis" ]
[ "Cytokine" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Interleukin" ]
null
null
null
null
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 71: Lymphoma - Inflammatory response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 82: Salivary gland - Secretion
Group enriched
Detected in some
4
Cancer enhanced
Detected in single
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,091
1
ENSG00000142227
EMP3
Epithelial membrane protein 3
[ "P54852" ]
19
48321509-48330553
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA062030" ]
[ "YMP" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Vesicles", "Plasma membrane" ]
[]
[]
[]
Approved
null
null
45
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 39: Astrocytes - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 82: Dendritic cells - Antigen presentation
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
8,092
7
ENSG00000142230
SAE1
SUMO1 activating enzyme subunit 1
[ "Q9UBE0" ]
19
47113274-47210636
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041906", "HPA043552" ]
[ "AOS1", "FLJ3091", "Sua1" ]
[ "Essential proteins", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Ligase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Enhanced
Supported
null
33
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 1: Neurons - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 65: Non-specific - Cell growth & division
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
8,093
6
ENSG00000142233
NTN5
Netrin 5
[ "Q8WTR8" ]
19
48661407-48673081
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Neurogenesis" ]
[ "Developmental protein" ]
[]
[]
[]
[ "Secreted in brain" ]
[ "Developmental protein" ]
null
null
null
null
null
null
null
Cluster 13: Oligodendrocytes - Mixed function
Cluster 33: Sarcoma - Muscle contraction
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in some
null
Cancer enriched
Detected in single
6
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,094
6
ENSG00000142235
LMTK3
Lemur tyrosine kinase 3
[ "Q96Q04" ]
19
48485271-48513935
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040203", "HPA077070" ]
[ "KIAA1883", "LMR3", "PPP1R101", "TYKLM3" ]
[ "Enzymes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Cell Junctions" ]
[]
[]
Uncertain
Enhanced
Supported
12
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 10: Brain - Synaptic signal transduction
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
8,095
6
ENSG00000142252
GEMIN7
Gem nuclear organelle associated protein 7
[ "Q9H840" ]
19
45079195-45091518
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052075" ]
[ "FLJ13956" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
null
null
31
null
null
Cluster 14: Non-specific - Unknown function
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 4: Non-specific - Transcription
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 5: Spleen - Immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in single
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
8,096
6
ENSG00000142273
CBLC
Cbl proto-oncogene C
[ "Q9ULV8" ]
19
44777869-44800652
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB008087", "HPA035266" ]
[ "CBL-3", "CBL-SL", "RNF57" ]
[ "Cancer-related genes", "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Transferase" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[ "Aggresome" ]
[]
[]
Approved
Approved
null
20
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 77: Intestine - Digestion
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
8,097
2
ENSG00000142279
WTIP
WT1 interacting protein
[ "A6NIX2" ]
19
34481758-34512304
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[]
[ "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation", "RNA-mediated gene silencing", "Transcription", "Transcription regulation" ]
[ "Repressor" ]
[]
[]
[]
[]
[]
null
null
null
4
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 15: Kidney cancer - Membrane components
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,098
4
ENSG00000142303
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif 10
[ "Q9H324" ]
19
8580240-8610735
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA040223" ]
[ "ADAM-TS10" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[ "Disease variant", "Dwarfism" ]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "Enzyme" ]
null
Uncertain
null
null
null
null
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 35: RS4;11 - Unknown function
Cluster 22: Non-specific - Basic cellular functions
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
8,099
3
ENSG00000142319
SLC6A3
Solute carrier family 6 member 3
[ "Q01959" ]
5
1392794-1445440
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA012763", "HPA013602", "CAB016249", "CAB078172" ]
[ "DAT", "DAT1" ]
[ "Disease related genes", "FDA approved drug targets", "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Neurotransmitter transport", "Symport", "Transport" ]
[]
[ "Disease variant", "Dystonia", "FDA approved drug targets", "Neurodegeneration", "Parkinsonism" ]
[ "Vesicles" ]
[]
[]
[]
Approved
Enhanced
Supported
14
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 15: Kidney cancer - Membrane components
Cluster 109: Neurons - Neuronal signaling
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in single
119
Cancer enriched
Detected in single
10
Cancer enriched
Detected in single
16
Cell type enriched
Detected in some
7
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,100
8
ENSG00000142327
RNPEPL1
Arginyl aminopeptidase like 1
[ "Q9HAU8" ]
2
240565804-240581372
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036772", "HPA036773" ]
[]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Aminopeptidase", "Hydrolase", "Metalloprotease", "Protease" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 25: Non-specific - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 35: RS4;11 - Unknown function
Cluster 47: Platelets - Hemostasis
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Bladder Urothelial Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
8,101
4
ENSG00000142330
CAPN10
Calpain 10
[ "Q9HC96" ]
2
240586734-240617705
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004170" ]
[]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protease", "Thiol protease" ]
[ "Diabetes mellitus" ]
[ "Mitochondria", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
15
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 15: Non-specific - Transcription
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
8,102
2
ENSG00000142347
MYO1F
Myosin IF
[ "O00160" ]
19
8520778-8577577
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA055242", "HPA056036" ]
[]
[ "Disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Actin-binding", "Calmodulin-binding", "Motor protein", "Myosin" ]
[ "Deafness", "Disease variant", "Non-syndromic deafness" ]
[ "Cytosol" ]
[]
[]
[]
Enhanced
Enhanced
null
13
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 20: Macrophages & Microglia - Immune response
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 66: Lymphoid tissue - Immune response
Group enriched
Detected in many
5
Cancer enriched
Detected in some
8
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
0
0
0
[]
[]
[]
8,103
4
ENSG00000142396
ERVK3-1
Endogenous retrovirus group K3 member 1
[]
19
58305374-58316812
Evidence at transcript level
Evidence at transcript level
null
null
[]
[ "HERV-K(HML6-1)" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 27: Non-specific - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 15: Non-specific - Protein processing
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
8,104
6
ENSG00000142405
NLRP12
NLR family pyrin domain containing 12
[ "P59046" ]
19
53793741-53824403
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042981" ]
[ "CLR19.3", "Monarch1", "NALP12", "PAN6", "PYPAF7", "RNO2" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
3
null
null
Cluster 35: Neutrophils - Protein binding
null
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in single
null
Cancer enriched
Detected in single
6
Group enriched
Detected in some
4
Group enriched
Detected in many
4
0
0
0
[]
[]
[]
8,105
6
ENSG00000142408
CACNG8
Calcium voltage-gated channel auxiliary subunit gamma 8
[ "Q8WXS5" ]
19
53962937-53990215
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA041351" ]
[]
[ "FDA approved drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[ "Calcium channel", "Ion channel", "Voltage-gated channel" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
Cluster 46: Basophils - Proteolysis
Cluster 51: Neurons - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in single
41
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
9
0
0
0
[]
[]
[]
8,106
5
ENSG00000142409
ZNF787
Zinc finger protein 787
[ "Q6DD87" ]
19
56087366-56121295
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA035140" ]
[]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli", "Mitochondria" ]
[]
[]
Approved
Supported
null
5
null
null
Cluster 41: Basophils - Unknown function
Cluster 18: Non-specific - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
8,107
8
ENSG00000142444
TIMM29
Translocase of inner mitochondrial membrane 29
[ "Q9BSF4" ]
19
10928811-10933535
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041858" ]
[ "C19orf52", "TIM29" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Protein transport", "Translocation", "Transport" ]
[]
[]
[ "Mitochondria" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Approved
null
11
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 32: Cerebral cortex - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Stomach Adenocarcinoma" ]
[]
[ "Stomach Adenocarcinoma" ]
8,108
6
ENSG00000142449
FBN3
Fibrillin 3
[ "Q75N90" ]
19
8065402-8149592
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA049482" ]
[ "KIAA1776" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
null
Uncertain
null
null
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 15: Kidney cancer - Membrane components
Cluster 50: Renal epithelial cells - Ion transport and pH regulation
Cluster 72: Kidney - Transmembrane transport
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,109
4
ENSG00000142453
CARM1
Coactivator associated arginine methyltransferase 1
[ "Q86X55" ]
19
10871553-10923075
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB032961", "HPA043561", "HPA048073", "HPA069313" ]
[ "PRMT4" ]
[ "Cancer-related genes", "Enzymes", "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Methyltransferase", "Transferase" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Supported
null
63
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 23: Non-specific - Transcription
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Lung Adenocarcinoma" ]
[ "Lung Adenocarcinoma" ]
8,110
9
ENSG00000142459
EVI5L
Ecotropic viral integration site 5 like
[ "Q96CN4" ]
19
7830218-7864976
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043099" ]
[]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "GTPase activation" ]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus", "Cytosol" ]
[]
[]
Approved
Approved
null
13
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 23: Non-specific - Transcription
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
8,111
1
ENSG00000142484
TM4SF5
Transmembrane 4 L six family member 5
[ "O14894" ]
17
4771884-4783213
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA055674" ]
[]
[ "Predicted membrane proteins", "Transporters" ]
[ "Cell cycle" ]
[]
[]
[ "Plasma membrane", "Cell Junctions" ]
[ "Nucleoplasm" ]
[]
[]
Uncertain
null
null
3
null
null
null
null
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 77: Intestine - Digestion
Group enriched
Detected in some
7
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
8
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
8,112
3
ENSG00000142507
PSMB6
Proteasome 20S subunit beta 6
[ "P28072" ]
17
4796144-4798502
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023312", "HPA063656" ]
[ "DELTA", "Y" ]
[ "Enzymes", "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[ "Hydrolase", "Protease", "Threonine protease" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[ "Mitochondria" ]
[]
[]
Supported
Supported
null
105
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 27: Non-specific - Mixed function
Cluster 42: Non-specific - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
8,114
3
ENSG00000142511
GPR32
G protein-coupled receptor 32
[ "O75388" ]
19
50770464-50771732
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[]
[ "RVDR1" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
null
Cluster 34: Testis cancer - Unknown function
Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio
Cluster 69: Parathyroid gland - Mixed function
Tissue enriched
Detected in some
32
Cancer enriched
Detected in single
30
Not detected
Not detected
null
Group enriched
Detected in some
5
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,115
6
ENSG00000142512
SIGLEC10
Sialic acid binding Ig like lectin 10
[ "Q96LC7" ]
19
51410020-51417803
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB025807", "HPA027093" ]
[ "MGC126774", "PRO940", "SIGLEC-10", "SLG2" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Adaptive immunity", "Cell adhesion", "Immunity", "Innate immunity" ]
[]
[]
[ "Cytosol" ]
[ "Plasma membrane", "Actin filaments" ]
[ "Intracellular and membrane" ]
[ "Immunity" ]
Supported
Enhanced
null
null
null
null
Cluster 25: Non-specific - Unknown function
Cluster 30: White matter - Myelination
Cluster 46: Lymphoma - Humoral immune response
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Group enriched
Detected in many
6
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Group enriched
Detected in many
6
0
0
0
[]
[]
[]
8,116
5
ENSG00000142513
ACP4
Acid phosphatase 4
[ "Q9BZG2" ]
19
50790415-50795219
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA048882" ]
[ "ACPT" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins" ]
[]
[ "Hydrolase" ]
[ "Amelogenesis imperfecta", "Disease variant" ]
[ "Plasma membrane" ]
[ "Nuclear bodies", "Microtubules" ]
[]
[]
Approved
null
null
null
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 60: Prostate cancer - Unknown function
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 47: Testis - Mixed function
Group enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Not detected
Not detected
null
Cell type enriched
Detected in some
7
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,117
3
ENSG00000142515
KLK3
Kallikrein related peptidase 3
[ "P07288" ]
19
50854915-50860764
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB000070", "HPA000764" ]
[ "APS", "PSA" ]
[ "Cancer-related genes", "Enzymes", "FDA approved drug targets", "Plasma proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Protease", "Serine protease" ]
[ "Cancer-related genes", "FDA approved drug targets" ]
[]
[]
[ "Secreted in male reproductive system" ]
[ "Enzyme" ]
null
Enhanced
null
22
null
null
null
null
Cluster 60: Prostate cancer - Unknown function
Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid
Cluster 38: Non-specific - Basic cellular processes
Tissue enriched
Detected in many
318
Cancer enriched
Detected in some
1,800
Cancer enriched
Detected in many
1,441
Cell type enriched
Detected in some
147
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Rectum Adenocarcinoma" ]
[ "Rectum Adenocarcinoma" ]
8,118
3
ENSG00000142528
ZNF473
Zinc finger protein 473
[ "Q8WTR7" ]
19
50025714-50053414
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004191", "HPA073309" ]
[ "DKFZP434N043", "HZFP100", "KIAA1141" ]
[ "Predicted intracellular proteins" ]
[]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
17
null
null
Cluster 32: Basophils - Transcription
Cluster 46: Brainstem - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 47: Testis - Mixed function
Tissue enriched
Detected in all
6
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Colon Adenocarcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
8,119
8
ENSG00000142530
GARIN5A
Golgi associated RAB2 interactor 5A
[ "Q6IPT2" ]
19
50466785-50476848
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA048111" ]
[ "FAM71E1", "GARIL5" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoli fibrillar center" ]
[]
[]
[]
Approved
null
null
null
null
null
Cluster 41: Basophils - Unknown function
Cluster 45: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in many
8
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
5
Low immune cell specificity
Detected in some
null
2
0
2
[ "Rectum Adenocarcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Rectum Adenocarcinoma" ]
8,120
9
ENSG00000142534
RPS11
Ribosomal protein S11
[ "P62280" ]
19
49496365-49499708
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA032020", "HPA049719" ]
[ "S11" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein", "RNA-binding", "rRNA-binding" ]
[]
[ "Cytosol" ]
[ "Nucleoli", "Endoplasmic reticulum" ]
[]
[]
Approved
Uncertain
null
271
null
null
Cluster 18: Non-specific - Translation
Cluster 7: Non-specific - Ribosome
Cluster 25: Non-specific - Ribosome
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
8,121
8
ENSG00000142538
PTH2
Parathyroid hormone 2
[ "Q96A98" ]
19
49422419-49423441
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "TIP39" ]
[ "Predicted secreted proteins" ]
[]
[ "Neuropeptide" ]
[]
[]
[]
[ "Secreted in brain" ]
[ "Neuropeptide" ]
null
null
null
1
null
null
null
Cluster 2: Neurons - Nucleosome
Cluster 6: Leukemia - Signal transduction
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 71: Cerebellum - Nervous system development
Tissue enhanced
Detected in single
null
Cancer enhanced
Detected in single
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,122
9
ENSG00000142539
ENSG00000142539
Novel protein
[]
19
50415799-50428409
Evidence at protein level
Evidence at protein level
null
null
[ "HPA018523" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
Cluster 29: Non-specific - Unknown function
null
Cluster 35: RS4;11 - Unknown function
Cluster 82: Dendritic cells - Antigen presentation
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in single
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
8,123
9
ENSG00000142541
RPL13A
Ribosomal protein L13a
[ "P40429" ]
19
49487510-49493057
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038751" ]
[ "L13A", "TSTA1" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[ "Translation regulation" ]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[ "Nucleoli", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
258
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 7: Non-specific - Ribosome
Cluster 25: Non-specific - Ribosome
Cluster 15: Non-specific - Protein processing
Cluster 54: Non-specific - Ribosome
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Lung Squamous Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Squamous Cell Carcinoma" ]
8,124
8
ENSG00000142544
CTU1
Cytosolic thiouridylase subunit 1
[ "Q7Z7A3" ]
19
51097606-51108409
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052664", "HPA053797" ]
[ "ATPBD3", "MGC17332", "NCS6" ]
[ "Predicted intracellular proteins" ]
[ "tRNA processing" ]
[ "RNA-binding", "Transferase", "tRNA-binding" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Uncertain
null
18
null
null
null
Cluster 6: Non-specific - Immune response
Cluster 4: Non-specific - Transcription
Cluster 17: Non-specific - RNA processing
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
8,125
6
ENSG00000142546
NOSIP
Nitric oxide synthase interacting protein
[ "Q9Y314" ]
19
49555468-49590262
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043464", "HPA062132" ]
[ "CGI-25" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Developmental protein", "Transferase" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Approved
null
14
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 45: Non-specific - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
8,126
4
ENSG00000142549
IGLON5
IgLON family member 5
[ "A6NGN9" ]
19
51311644-51330891
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041994" ]
[ "LOC402665" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted in brain" ]
[ "No annotated function" ]
null
Approved
null
null
null
null
null
Cluster 49: Hindbrain - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 109: Neurons - Neuronal signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enriched
Detected in some
5
Group enriched
Detected in some
8
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,127
9
ENSG00000142556
ZNF614
Zinc finger protein 614
[ "Q8N883" ]
19
52012765-52030240
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA021197" ]
[ "FLJ21941" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Approved
Uncertain
null
3
No
No
Cluster 5: Non-specific - Cell proliferation
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 4: Non-specific - Transcription
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 40: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma" ]
8,129
4
ENSG00000142599
RERE
Arginine-glutamic acid dipeptide repeats
[ "Q9P2R6" ]
1
8352397-8848921
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024093" ]
[ "ARG", "ARP", "ATN1L", "ATN2", "DNB1", "KIAA0458" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Developmental protein", "Repressor" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nuclear bodies" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Uncertain
null
17
null
null
Cluster 14: Non-specific - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
8,131
2
ENSG00000142606
MMEL1
Membrane metalloendopeptidase like 1
[ "Q495T6" ]
1
2590639-2633016
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA007876", "HPA008205", "CAB020786" ]
[ "MMEL2", "NEPII", "NL1", "NL2", "SEP" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Metalloprotease", "Protease" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
null
Uncertain
null
null
null
null
Cluster 25: Non-specific - Unknown function
Cluster 46: Brainstem - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 79: Testis - Spermatogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in many
null
0
0
0
[]
[]
[]
8,132
4
ENSG00000142609
CFAP74
Cilia and flagella associated protein 74
[ "Q9C0B2" ]
1
1921951-2003837
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA028521", "HPA029274", "HPA030240" ]
[ "C1orf222", "FLJ45476", "KIAA1751" ]
[ "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Ciliopathy", "Disease variant", "Primary ciliary dyskinesia" ]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 56: Non-specific - Sensory perception
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Lung Squamous Cell Carcinoma" ]
[]
[ "Lung Squamous Cell Carcinoma" ]
8,133
8
ENSG00000142611
PRDM16
PR/SET domain 16
[ "Q9HAZ2" ]
1
3069168-3438621
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA050343", "HPA051662" ]
[ "KIAA1675", "KMT8F", "MEL1", "MGC166915", "PFM13" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding", "Methyltransferase", "Repressor", "Transferase" ]
[ "Cancer-related genes", "Cardiomyopathy", "Disease variant" ]
[ "Nucleoplasm" ]
[ "Nuclear bodies", "Cytosol" ]
[]
[]
Supported
null
null
8
null
null
Cluster 15: NK-cells - Unknown function
Cluster 23: Choroid plexus - Mixed function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 101: Choroid plexus epithelial cells - Ion transport
Cluster 74: Non-specific - Signal transduction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
16
1
0
1
[]
[ "Thyroid Carcinoma" ]
[ "Thyroid Carcinoma" ]
8,134
2
ENSG00000142615
CELA2A
Chymotrypsin like elastase 2A
[ "P08217" ]
1
15456728-15472091
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "ELA2A" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Protease", "Serine protease" ]
[ "Diabetes mellitus", "Disease variant", "Obesity" ]
[]
[]
[ "Secreted to digestive system" ]
[ "Enzyme" ]
null
null
null
3
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 5: Pancreatic acinar cells - Pancreatic exocrine secretion
Cluster 8: Pancreas - Proteolysis
Tissue enriched
Detected in many
5,457
Not detected
Not detected
null
Cancer enriched
Detected in single
6,560
Cell type enriched
Detected in some
130
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,135
4
ENSG00000142619
PADI3
Peptidyl arginine deiminase 3
[ "Q9ULW8" ]
1
17249098-17284233
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043739" ]
[ "PDI3" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[ "Disease variant" ]
[ "Vesicles", "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Supported
null
null
13
null
null
null
null
Cluster 15: Kidney cancer - Membrane components
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 11: Esophagus - Basic cellular processes
Group enriched
Detected in some
6
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
29
Not detected in immune cells
Not detected
null
1
0
1
[ "Colon Adenocarcinoma" ]
[]
[ "Colon Adenocarcinoma" ]
8,136
1
ENSG00000142621
FHAD1
Forkhead associated phosphopeptide binding domain 1
[ "B1AJZ9" ]
1
15236521-15400283
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA054284" ]
[ "KIAA1937" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Nuclear bodies" ]
[]
[]
[]
Approved
Enhanced
null
null
null
null
Cluster 15: NK-cells - Unknown function
Cluster 3: Choroid plexus - Cilium
Cluster 49: HMC-1 - Innate immune response
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
8,137
4
ENSG00000142623
PADI1
Peptidyl arginine deiminase 1
[ "Q9ULC6" ]
1
17205128-17246007
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA062294" ]
[ "HPAD10", "PAD1", "PDI", "PDI1" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
1
null
null
null
null
Cluster 15: Kidney cancer - Membrane components
Cluster 109: Neurons - Neuronal signaling
Cluster 81: Squamous epithelium - Keratinization
Tissue enriched
Detected in some
6
Group enriched
Detected in many
4
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
8,138
7
ENSG00000142627
EPHA2
EPH receptor A2
[ "P29317" ]
1
16124337-16156069
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB010464" ]
[ "ECK" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Predicted membrane proteins", "RAS pathway related proteins" ]
[ "Angiogenesis", "Apoptosis", "Cell adhesion", "Differentiation", "Host-virus interaction" ]
[ "Host cell receptor for virus entry", "Kinase", "Receptor", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "Cataract", "Disease variant", "FDA approved drug targets" ]
[ "Plasma membrane", "Cell Junctions" ]
[ "Nuclear speckles", "Golgi apparatus" ]
[]
[]
Supported
null
null
128
null
Yes
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 42: Choroid plexus - Mitochondria
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
94
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
8,139
4