ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000157353
FCSK
Fucose kinase
[ "Q8N0W3" ]
16
70454595-70480274
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041971" ]
[ "FLJ39408", "FUK" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Kinase", "Transferase" ]
[ "Congenital disorder of glycosylation", "Disease variant" ]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
2
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 25: Non-specific - Transcription
Cluster 68: Non-specific - Cell cycle regulation
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
9,932
1
ENSG00000157368
IL34
Interleukin 34
[ "Q6ZMJ4" ]
16
70579895-70660682
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C16orf77", "IL-34", "MGC34647" ]
[ "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Immunity", "Inflammatory response", "Innate immunity" ]
[ "Cytokine", "Growth factor" ]
[]
[]
[]
[ "Secreted to blood" ]
[ "Interleukin" ]
null
null
null
1
null
null
Cluster 22: Eosinophils - Transcription
Cluster 29: Forebrain - Mixed function
Cluster 66: Non-specific - Mitochondria
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 5: Spleen - Immune response
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
13
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
9,933
2
ENSG00000157379
DHRS1
Dehydrogenase/reductase 1
[ "Q96LJ7" ]
14
24290598-24299780
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000599", "HPA076886" ]
[ "FLJ25430", "MGC20204", "SDR19C1" ]
[ "Predicted intracellular proteins" ]
[]
[ "Oxidoreductase" ]
[]
[ "Nucleoplasm" ]
[ "Centrosome", "Cytosol" ]
[]
[]
Approved
Approved
null
30
null
null
Cluster 25: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
9,934
6
ENSG00000157388
CACNA1D
Calcium voltage-gated channel subunit alpha1 D
[ "Q01668" ]
3
53328963-53813733
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA020215" ]
[ "CACH3", "CACN4", "CACNL1A2", "Cav1.3", "CCHL1A2" ]
[ "Cancer-related genes", "Disease related genes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[ "Calcium channel", "Ion channel", "Voltage-gated channel" ]
[ "Cancer-related genes", "Deafness", "Disease variant", "Epilepsy", "FDA approved drug targets" ]
[ "Nuclear membrane" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 46: Basophils - Proteolysis
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 50: Lymphoma - Unknown function
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 22: Epididymis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
9
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
9,935
6
ENSG00000157399
ARSL
Arylsulfatase L
[ "P51690" ]
X
2934045-2968475
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA060518", "HPA070651" ]
[ "ARSE", "CDPX", "CDPX1" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Hydrolase" ]
[ "Disease variant" ]
[ "Golgi apparatus" ]
[]
[]
[]
Supported
Approved
null
null
null
null
null
Cluster 44: Non-specific - Mixed function
Cluster 18: Liver cancer - Metabolism
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 8: Pancreas - Proteolysis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
9,936
5
ENSG00000157404
KIT
KIT proto-oncogene, receptor tyrosine kinase
[ "P10721" ]
4
54657267-54740783
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB003288", "HPA004471", "CAB068253", "CAB072867", "HPA073252" ]
[ "C-Kit", "CD117", "PBT", "SCFR" ]
[ "Cancer-related genes", "CD markers", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "RAS pathway related proteins" ]
[]
[ "Kinase", "Receptor", "Transferase", "Tyrosine-protein kinase" ]
[ "Cancer-related genes", "Disease variant", "FDA approved drug targets", "Proto-oncogene" ]
[ "Plasma membrane" ]
[ "Nucleoli fibrillar center" ]
[]
[]
Supported
Enhanced
Supported
42
null
null
Cluster 32: Basophils - Transcription
Cluster 35: Non-specific - DNA binding
Cluster 49: HMC-1 - Innate immune response
Cluster 58: Mast cells - Allergic inflammatory responses
Cluster 55: Breast - Lactation
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
6
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
9,937
4
ENSG00000157426
AASDH
Aminoadipate-semialdehyde dehydrogenase
[ "Q4L235" ]
4
56338287-56387508
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036472", "HPA036473" ]
[ "ACSF4", "LYS2", "NRPS998" ]
[ "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Fatty acid metabolism", "Lipid metabolism" ]
[ "Ligase" ]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 55: Non-specific - Transcription
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
9,939
5
ENSG00000157429
ZNF19
Zinc finger protein 19
[ "P17023" ]
16
71464555-71565089
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA063685" ]
[ "KOX12", "MGC51021" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Approved
null
24
null
null
Cluster 14: Non-specific - Unknown function
Cluster 17: Choroid plexus - Cilium
Cluster 7: Liver cancer - Metabolism
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
9,940
6
ENSG00000157445
CACNA2D3
Calcium voltage-gated channel auxiliary subunit alpha2delta 3
[ "Q8IZS8" ]
3
54122547-55074557
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030849" ]
[ "alpha2delta-3", "HSA272268" ]
[ "FDA approved drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Calcium transport", "Ion transport", "Transport" ]
[ "Calcium channel", "Ion channel", "Voltage-gated channel" ]
[ "FDA approved drug targets" ]
[ "Nucleoplasm", "Principal piece" ]
[]
[]
[]
Uncertain
null
null
null
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in single
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
9,941
2
ENSG00000157450
RNF111
Ring finger protein 111
[ "Q6ZNA4" ]
15
58865175-59097419
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038576", "HPA038577" ]
[ "ARK", "Arkadia", "DKFZP761D081", "FLJ38008" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Ubl conjugation pathway" ]
[ "Developmental protein", "Transferase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Enhanced
null
50
null
null
Cluster 20: Non-specific - DNA binding
Cluster 31: Non-specific - Transcription
Cluster 58: Non-specific - Nuclear processes
Cluster 89: Adipocytes - Lipid metabolism
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
9,942
3
ENSG00000157456
CCNB2
Cyclin B2
[ "O95067" ]
15
59105126-59125045
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA008873", "CAB009575" ]
[ "HsT17299" ]
[ "Cancer-related genes", "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Cell cycle", "Cell division", "Mitosis" ]
[ "Cyclin" ]
[ "Cancer-related genes" ]
[ "Cytosol" ]
[ "Golgi apparatus" ]
[]
[]
Enhanced
Enhanced
null
27
Yes
Yes
Cluster 16: Non-specific - Cell proliferation
Cluster 11: White matter - Signal transduction
Cluster 58: Non-specific - Nuclear processes
Cluster 27: Non-specific - Cell proliferation
Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation
Group enriched
Detected in many
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in many
4
Immune cell enriched
Detected in many
5
6
6
3
[]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
9,943
4
ENSG00000157470
FAM81A
Family with sequence similarity 81 member A
[ "Q8TBF8" ]
15
59372693-59523555
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001847", "HPA065797" ]
[ "MGC26690" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
5
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 53: Neurons - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 78: Brain - Neuronal signaling
Tissue enriched
Detected in many
4
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
9,944
2
ENSG00000157483
MYO1E
Myosin IE
[ "Q12965" ]
15
59132434-59372871
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003003", "HPA023886" ]
[ "HuncM-IC", "MGC104638", "MYO1C" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Actin-binding", "Calmodulin-binding", "Motor protein", "Myosin" ]
[ "Disease variant" ]
[ "Nucleoplasm", "Plasma membrane" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
38
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 11: White matter - Signal transduction
Cluster 46: Lymphoma - Humoral immune response
Cluster 51: Secretory epithelial cells - Mixed function
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
9,945
3
ENSG00000157500
APPL1
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
[ "Q9UKG1" ]
3
57227726-57278105
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011138" ]
[ "APPL" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cell cycle" ]
[]
[ "Diabetes mellitus", "Disease variant" ]
[ "Vesicles", "Plasma membrane" ]
[ "Actin filaments", "Cytosol" ]
[]
[]
Supported
Approved
null
108
null
No
Cluster 34: B-cells - Unknown function
Cluster 55: Non-specific - Transcription
Cluster 8: Non-specific - Basic cellular processes
Cluster 82: Dendritic cells - Antigen presentation
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
9,946
9
ENSG00000157502
PWWP3B
PWWP domain containing 3B
[ "Q5H9M0" ]
X
106168305-106208956
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA000168", "HPA020464" ]
[ "FLJ33516", "MUM1L1" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 27: Breast cancer - Unknown function
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
9,947
5
ENSG00000157510
AFAP1L1
Actin filament associated protein 1 like 1
[ "Q8TED9" ]
5
149271859-149343637
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FLJ36748" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
4
null
null
null
Cluster 47: Endothelial cells - Vasculature
Cluster 69: Skin cancer - ECM organization
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
9,948
2
ENSG00000157514
TSC22D3
TSC22 domain family member 3
[ "Q99576" ]
X
107713221-107777342
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA001916", "CAB034364" ]
[ "DIP", "DSIPI", "GILZ", "hDIP", "TSC-22R" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[]
[]
[]
[ "Cytosol" ]
[ "Nuclear speckles", "Golgi apparatus" ]
[]
[]
Approved
Approved
null
23
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
9,949
2
ENSG00000157538
VPS26C
VPS26 endosomal protein sorting factor C
[ "O14972" ]
21
37223420-37267919
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023288" ]
[ "DCRA", "DSCR3" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[]
[]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
Supported
null
50
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 27: Non-specific - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
9,950
3
ENSG00000157540
DYRK1A
Dual specificity tyrosine phosphorylation regulated kinase 1A
[ "Q13627" ]
21
37365573-37526358
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA015323", "HPA015810", "HPA015813" ]
[ "DYRK", "DYRK1", "MNBH" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Kinase", "Serine/threonine-protein kinase", "Transferase", "Tyrosine-protein kinase" ]
[ "Intellectual disability" ]
[ "Nuclear speckles" ]
[ "Nucleoplasm", "Centrosome", "Cytosol" ]
[]
[]
Supported
Approved
null
206
null
null
Cluster 20: Non-specific - DNA binding
Cluster 31: Non-specific - Transcription
Cluster 47: Leukemia - Hemostasis
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
9,951
3
ENSG00000157542
KCNJ6
Potassium inwardly rectifying channel subfamily J member 6
[ "P48051" ]
21
37607373-38121345
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "BIR1", "GIRK2", "hiGIRK2", "KATP2", "KCNJ7", "Kir3.2" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Voltage-gated channel" ]
[ "Congenital generalized lipodystrophy", "Disease variant", "Intellectual disability" ]
[]
[]
[]
[]
null
null
null
52
null
null
null
Cluster 1: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 27: Cerebellum - Synaptic function
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
9,952
8
ENSG00000157551
KCNJ15
Potassium inwardly rectifying channel subfamily J member 15
[ "Q99712" ]
21
38155549-38307357
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA016702" ]
[ "IRKK", "Kir1.3", "Kir4.2" ]
[ "FDA approved drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Voltage-gated ion channels" ]
[ "Ion transport", "Potassium transport", "Transport" ]
[ "Ion channel", "Voltage-gated channel" ]
[ "FDA approved drug targets" ]
[ "Plasma membrane" ]
[ "Vesicles", "Cytosol" ]
[]
[]
Approved
Approved
null
3
null
null
Cluster 4: Neutrophils - Degranulation
Cluster 12: Non-specific - Vasculature
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 72: Kidney - Transmembrane transport
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Immune cell enriched
Detected in some
21
3
2
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
9,953
6
ENSG00000157554
ERG
ETS transcription factor ERG
[ "P11308" ]
21
38380027-38661780
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB018377", "HPA046598" ]
[ "erg-3", "p55" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[ "Cancer-related genes", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
83
null
null
null
Cluster 47: Endothelial cells - Vasculature
Cluster 6: Leukemia - Signal transduction
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Group enriched
Detected in some
9
Group enriched
Detected in all
4
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
4
2
3
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
9,954
6
ENSG00000157570
TSPAN18
Tetraspanin 18
[ "Q96SJ8" ]
11
44726465-44932423
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "TSPAN" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
11
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 35: Non-specific - DNA binding
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 35: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Group enriched
Detected in many
5
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
9,956
5
ENSG00000157578
LCA5L
Lebercilin LCA5 like
[ "O95447" ]
21
39405728-39445805
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA032010" ]
[ "C21orf13", "MGC33295" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Nuclear speckles", "Flagellar centriole", "Mid piece" ]
[ "Cytosol", "Principal piece", "End piece" ]
[]
[]
Approved
Enhanced
null
14
null
null
null
Cluster 17: Choroid plexus - Cilium
Cluster 27: Breast cancer - Unknown function
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 57: Testis - Spermatogenesis
Tissue enriched
Detected in many
10
Low cancer specificity
Detected in some
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
8
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
9,957
6
ENSG00000157593
SLC35B2
Solute carrier family 35 member B2
[ "Q8TB61" ]
6
44254096-44257890
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA029638" ]
[ "UGTrel4" ]
[ "Metabolic proteins", "Predicted membrane proteins", "Transporters" ]
[ "Antiport", "Transport" ]
[]
[ "Leukodystrophy" ]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
14
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 13: Oligodendrocytes - Mixed function
Cluster 28: Non-specific - Nuclear processes
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
9,958
7
ENSG00000157600
TMEM164
Transmembrane protein 164
[ "Q5U3C3" ]
X
110002631-110182734
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA038784" ]
[ "FLJ22679", "RP13-360B22.2" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Cell Junctions" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 41: Basophils - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 49: HMC-1 - Innate immune response
Cluster 89: Adipocytes - Lipid metabolism
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
2
1
[ "Stomach Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Stomach Adenocarcinoma" ]
9,959
8
ENSG00000157601
MX1
MX dynamin like GTPase 1
[ "P20591" ]
21
41420020-41470071
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA030917", "HPA030918", "HPA049724" ]
[ "IFI-78K", "lncMX1-215", "MxA" ]
[ "Predicted intracellular proteins" ]
[ "Antiviral defense", "Immunity", "Innate immunity" ]
[]
[]
[ "Nuclear membrane", "Cytosol" ]
[]
[]
[]
Supported
Approved
Approved
18
No
null
Cluster 13: Non-specific - Mitochondria
Cluster 43: Hindbrain - Mixed function
Cluster 31: Non-specific - Antiviral immune response
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 66: Lymphoid tissue - Immune response
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
9,960
2
ENSG00000157613
CREB3L1
CAMP responsive element binding protein 3 like 1
[ "Q96BA8" ]
11
46277662-46321409
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024069", "CAB026151", "HPA062116" ]
[ "OASIS" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins", "Transcription factors" ]
[ "Host-virus interaction", "Transcription", "Transcription regulation", "Unfolded protein response" ]
[ "Activator", "Developmental protein", "DNA-binding" ]
[ "Cancer-related genes", "Osteogenesis imperfecta" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
172
null
null
null
Cluster 14: Neurons - Synaptic function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 60: Stomach - Digestion
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
4
0
4
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Rectum Adenocarcinoma", "Thyroid Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Rectum Adenocarcinoma", "Thyroid Carcinoma" ]
9,961
8
ENSG00000157617
C2CD2
C2 calcium dependent domain containing 2
[ "Q9Y426" ]
21
41885112-41954018
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA030922", "HPA030924" ]
[ "C21orf25", "C21orf258", "DKFZP586F0422", "TMEM24L" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Enhanced
null
1
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 18: Adrenal cortex cells - Steroidogensis
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Breast Invasive Carcinoma", "Thyroid Carcinoma" ]
[ "Breast Invasive Carcinoma", "Thyroid Carcinoma" ]
9,962
4
ENSG00000157637
SLC38A10
Solute carrier family 38 member 10
[ "Q9HBR0" ]
17
81244811-81295547
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021374", "HPA023161", "HPA024631" ]
[ "MGC15523", "PP1744" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Amino-acid transport", "Transport" ]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Enhanced
Enhanced
null
22
null
null
Cluster 25: Non-specific - Unknown function
Cluster 18: Non-specific - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Pancreatic Adenocarcinoma" ]
[]
[ "Pancreatic Adenocarcinoma" ]
9,964
1
ENSG00000157653
C9orf43
Chromosome 9 open reading frame 43
[ "Q8TAL5" ]
9
113410054-113429690
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA021310" ]
[ "MGC17358" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
null
null
1
null
null
Cluster 14: Non-specific - Unknown function
Cluster 46: Brainstem - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 6: Testis - Spermatogenesis
Tissue enriched
Detected in some
24
Low cancer specificity
Detected in some
null
Not detected
Not detected
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
9,965
5
ENSG00000157654
PALM2AKAP2
PALM2 and AKAP2 fusion
[ "Q8IXS6", "Q9Y2D5" ]
9
109498325-110172512
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058905", "HPA074153", "HPA076866" ]
[ "PALM2-AKAP2" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[]
[]
[]
Supported
Uncertain
null
5
null
null
Cluster 17: B-cells - Immunoglobulins
Cluster 38: Sub-cortical - Mixed function
Cluster 72: Neuronal - Signal transduction
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
9,966
4
ENSG00000157657
ZNF618
Zinc finger protein 618
[ "Q5T7W0" ]
9
113876282-114056593
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023116", "HPA061732" ]
[ "KIAA1952", "NEDD10" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
13
null
null
Cluster 41: Basophils - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 50: Renal epithelial cells - Ion transport and pH regulation
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
9,967
4
ENSG00000157693
TMEM268
Transmembrane protein 268
[ "Q5VZI3" ]
9
114611206-114646422
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA017199" ]
[ "C9orf91", "DKFZp547P234", "FLJ38045" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
1
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 53: Neurons - Mixed function
Cluster 13: Non-specific - Mixed function
Cluster 99: Retinal pigment epithelial cells - Retinol metabolism
Cluster 73: Brain - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
1
0
1
[]
[ "Thyroid Carcinoma" ]
[ "Thyroid Carcinoma" ]
9,969
5
ENSG00000157703
SVOPL
SVOP like
[ "Q8N434" ]
7
138594285-138701362
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018035" ]
[ "MGC46715" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
null
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 50: Renal epithelial cells - Ion transport and pH regulation
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
14
2
0
2
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
9,970
5
ENSG00000157734
SNX22
Sorting nexin 22
[ "Q96L94" ]
15
64151715-64157481
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038470" ]
[ "FLJ13952" ]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
null
null
2
null
null
Cluster 18: Non-specific - Translation
Cluster 43: Hindbrain - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc
Cluster 3: Oligodendrocytes - Myelination
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enriched
Detected in many
7
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
5
2
0
2
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Breast Invasive Carcinoma", "Lung Adenocarcinoma" ]
9,971
3
ENSG00000157741
UBN2
Ubinuclein 2
[ "Q6ZU65" ]
7
139230356-139308236
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019743", "HPA020122", "HPA020124" ]
[ "FLJ25778", "KIAA2030" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Uncertain
null
18
null
null
Cluster 20: Non-specific - DNA binding
Cluster 31: Non-specific - Transcription
Cluster 39: Non-specific - Transcription
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 47: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
4
2
0
2
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
9,972
6
ENSG00000157764
BRAF
B-Raf proto-oncogene, serine/threonine kinase
[ "P15056" ]
7
140719327-140924929
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA001328", "CAB004552", "HPA071048", "CAB080447", "CAB080451", "CAB080452", "CAB080531" ]
[ "BRAF-1", "BRAF1" ]
[ "Cancer-related genes", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Predicted intracellular proteins", "Transporters" ]
[]
[ "Allosteric enzyme", "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Cancer-related genes", "Cardiomyopathy", "Deafness", "Disease variant", "Ectodermal dysplasia", "FDA approved drug targets", "Intellectual disability", "Proto-oncogene" ]
[ "Vesicles", "Cytosol" ]
[ "Plasma membrane", "Primary cilium", "Centriolar satellite", "Basal body", "Mid piece", "Principal piece", "End piece" ]
[]
[]
Supported
Supported
null
174
No
No
Cluster 20: Non-specific - DNA binding
Cluster 31: Non-specific - Transcription
Cluster 39: Non-specific - Transcription
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 44: Bone marrow - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
3
2
2
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
9,973
9
ENSG00000157765
SLC34A2
Solute carrier family 34 member 2
[ "O95436" ]
4
25648011-25678748
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA037989", "HPA066474" ]
[ "NAPI-3B" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Sodium transport", "Symport", "Transport" ]
[]
[ "Cancer-related genes", "Disease variant" ]
[ "Plasma membrane" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Supported
Enhanced
null
13
null
null
null
Cluster 5: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 81: Alveolar cells - Lung function
Cluster 13: Lung - Secretion
Tissue enriched
Detected in many
8
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
9,974
8
ENSG00000157766
ACAN
Aggrecan
[ "P16112" ]
15
88803436-88875353
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB016377", "HPA038241", "HPA038242" ]
[ "AGC1", "CSPG1", "CSPGCP", "MSK16" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[ "Disease variant", "Dwarfism" ]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
null
Enhanced
null
1
null
null
null
Cluster 1: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enriched
Detected in some
12
Group enriched
Detected in some
4
Cancer enhanced
Detected in many
null
Cell type enriched
Detected in some
9
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Papillary Cell Carcinoma" ]
9,975
6
ENSG00000157778
PSMG3
Proteasome assembly chaperone 3
[ "Q9BT73" ]
7
1567332-1571005
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023876" ]
[ "C7orf48", "MGC10911", "PAC3" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[]
[ "Chaperone" ]
[]
[]
[]
[]
[]
null
Approved
null
62
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 14: Neurons - Synaptic function
Cluster 67: Non-specific - Unknown function
Cluster 97: Non-specific - Cellular respiration
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
2
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
9,976
1
ENSG00000157782
CABP1
Calcium binding protein 1
[ "Q9NZU7" ]
12
120640626-120667324
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA051438" ]
[]
[ "Predicted intracellular proteins", "Transporters" ]
[ "Sensory transduction", "Vision" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
5
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 53: Neurons - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 73: Brain - Neuronal signaling
Tissue enriched
Detected in many
18
Cancer enriched
Detected in some
25
Group enriched
Detected in many
4
Group enriched
Detected in many
4
Not detected in immune cells
Not detected
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
9,977
3
ENSG00000157796
WDR19
WD repeat domain 19
[ "Q8NEZ3" ]
4
39182504-39285810
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039616", "HPA058847" ]
[ "DYF-2", "FAP66", "FLJ23127", "IFT144", "KIAA1638", "NPHP13", "ORF26", "Oseg6", "Pwdmp" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[]
[ "Ciliopathy", "Disease variant", "Ectodermal dysplasia", "Leber congenital amaurosis", "Nephronophthisis", "Senior-Loken syndrome" ]
[ "Nucleoplasm", "Mid piece" ]
[ "Centrosome", "Basal body", "Cytosol", "Principal piece" ]
[]
[]
Uncertain
Approved
null
23
null
null
Cluster 24: Non-specific - Transcription
Cluster 17: Choroid plexus - Cilium
Cluster 5: Rhabdoid - Unknown function
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
9,978
2
ENSG00000157800
SLC37A3
Solute carrier family 37 member 3
[ "Q8NCC5" ]
7
140293693-140404433
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "DKFZp761N0624", "SPX3" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Sugar transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
null
null
5
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 34: Non-specific - Mixed function
Cluster 39: Non-specific - Transcription
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
9,979
6
ENSG00000157823
AP3S2
Adaptor related protein complex 3 subunit sigma 2
[ "P59780" ]
15
89830599-89894638
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA049270" ]
[ "sigma3b" ]
[ "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Uncertain
null
4
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 45: Non-specific - Mixed function
Cluster 58: Non-specific - Nuclear processes
Cluster 22: Non-specific - Basic cellular functions
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
9,980
3
ENSG00000157827
FMNL2
Formin like 2
[ "Q96PY5" ]
2
152335174-152649826
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA005464" ]
[ "FHOD2", "KIAA1902" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[ "Golgi apparatus", "Plasma membrane" ]
[]
[]
Approved
Enhanced
null
15
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 30: White matter - Myelination
Cluster 69: Skin cancer - ECM organization
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in many
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
0
0
0
[]
[]
[]
9,981
6
ENSG00000157833
GAREM2
GRB2 associated regulator of MAPK1 subtype 2
[ "Q75VX8" ]
2
26173088-26189663
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA071575" ]
[ "FAM59B", "FLJ00375", "GAREML", "KIAA2038" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
null
null
1
null
null
null
Cluster 19: Astrocytes - Mixed function
Cluster 65: Non-specific - Unknown function
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 73: Brain - Neuronal signaling
Group enriched
Detected in many
6
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
9,982
9
ENSG00000157837
SPPL3
Signal peptide peptidase like 3
[ "Q8TCT6" ]
12
120762510-120904358
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004194", "HPA059958" ]
[ "DKFZP586C1324", "IMP2", "MGC126674", "MGC126676", "MGC90402", "PSL4" ]
[ "Enzymes", "Predicted membrane proteins" ]
[]
[ "Hydrolase", "Protease" ]
[]
[ "Vesicles", "Plasma membrane" ]
[]
[]
[]
Supported
Uncertain
null
2
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 13: Oligodendrocytes - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
9,983
8
ENSG00000157851
DPYSL5
Dihydropyrimidinase like 5
[ "Q9BPU6" ]
2
26847747-26950351
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA034544", "HPA072387" ]
[ "CRAM", "CRMP-5", "CRMP5", "CV2", "Ulip6" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
27
null
null
null
Cluster 30: White matter - Myelination
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 80: Oligodendrocytes - Myelination
Cluster 3: Oligodendrocytes - Myelination
Tissue enriched
Detected in some
9
Group enriched
Detected in many
4
Group enriched
Detected in some
16
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
9,984
5
ENSG00000157869
RAB28
RAB28, member RAS oncogene family
[ "P51157" ]
4
13361354-13484365
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA044575" ]
[]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase" ]
[ "Cone-rod dystrophy" ]
[]
[]
[]
[]
null
Approved
null
8
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 31: Non-specific - Transcription
Cluster 51: Myeloma - Immunoglobulins
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 46: Brain & retina - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
9,986
6
ENSG00000157870
PRXL2B
Peroxiredoxin like 2B
[ "Q8TBF2" ]
1
2586491-2591469
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006403" ]
[ "C1orf93", "FAM213B", "MGC26818" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "Fatty acid biosynthesis", "Fatty acid metabolism", "Lipid biosynthesis", "Lipid metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism" ]
[ "Oxidoreductase" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
Approved
2
null
null
Cluster 33: Non-specific - ATP binding
Cluster 14: Neurons - Synaptic function
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 64: Renal epithelial cells - Ion transport & homeostasis
Cluster 68: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
9,987
1
ENSG00000157873
TNFRSF14
TNF receptor superfamily member 14
[ "Q92956" ]
1
2555639-2565382
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006404", "CAB026150", "CAB030007", "CAB080525", "CAB080526" ]
[ "ATAR", "CD270", "HVEA", "HVEM", "LIGHTR", "TR2" ]
[ "Cancer-related genes", "CD markers", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Adaptive immunity", "Host-virus interaction", "Immunity", "Innate immunity" ]
[ "Host cell receptor for virus entry", "Receptor" ]
[ "Cancer-related genes" ]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
12
null
null
Cluster 33: Non-specific - ATP binding
Cluster 12: Non-specific - Vasculature
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
9,988
3
ENSG00000157881
PANK4
Pantothenate kinase 4 (inactive)
[ "Q9NVE7" ]
1
2508537-2526597
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA011723", "HPA012036", "HPA027961" ]
[ "FLJ10782" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Coenzyme A biosynthesis" ]
[ "Hydrolase" ]
[ "Cataract" ]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
12
null
null
Cluster 45: Eosinophils - Unknown function
Cluster 23: Choroid plexus - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in single
null
2
0
2
[ "Glioblastoma Multiforme", "Thyroid Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Thyroid Carcinoma" ]
9,989
6
ENSG00000157884
CIB4
Calcium and integrin binding family member 4
[ "A0PJX0" ]
2
26581205-26641366
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA036130", "HPA036131" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
6
null
null
null
Cluster 49: Hindbrain - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase
Cluster 67: Testis - Mixed function
Tissue enriched
Detected in some
7
Not detected
Not detected
null
Group enriched
Detected in some
8
Group enriched
Detected in some
6
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
9,990
9
ENSG00000157890
MEGF11
Multiple EGF like domains 11
[ "A6BM72" ]
15
65895079-66253756
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "DKFZp434L121", "KIAA1781" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
1
null
null
null
Cluster 35: Non-specific - DNA binding
Cluster 6: Leukemia - Signal transduction
Cluster 14: Oligodendrocyte progenitor cells - Development & myelination
Cluster 27: Cerebellum - Synaptic function
Group enriched
Detected in some
4
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Glioblastoma Multiforme" ]
[]
[ "Glioblastoma Multiforme" ]
9,991
5
ENSG00000157895
C12orf43
Chromosome 12 open reading frame 43
[ "Q96C57" ]
12
121000486-121016502
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA046148", "HPA061739" ]
[ "Custos", "FLJ12448" ]
[ "Predicted intracellular proteins" ]
[ "Wnt signaling pathway" ]
[ "Developmental protein" ]
[]
[ "Nucleoli" ]
[ "Golgi apparatus" ]
[]
[]
Supported
Uncertain
null
11
null
null
Cluster 33: Non-specific - ATP binding
Cluster 1: Neurons - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 20: Non-specific - Transcription regulation
Cluster 73: Brain - Neuronal signaling
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
5
2
4
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
9,992
1
ENSG00000157911
PEX10
Peroxisomal biogenesis factor 10
[ "O60683" ]
1
2403964-2413797
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049755" ]
[ "RNF69" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Peroxisome biogenesis", "Protein transport", "Transport", "Ubl conjugation pathway" ]
[ "Transferase" ]
[ "Disease variant", "Peroxisome biogenesis disorder", "Zellweger syndrome" ]
[]
[]
[]
[]
null
Approved
null
3
null
null
Cluster 29: Non-specific - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 60: Prostate cancer - Unknown function
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
5
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
9,993
9
ENSG00000157916
RER1
Retention in endoplasmic reticulum sorting receptor 1
[ "O15258" ]
1
2391775-2405442
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB037240", "HPA051400" ]
[]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Supported
Supported
null
74
No
No
Cluster 42: Non-specific - Vesicular transport
Cluster 50: Non-specific - Nucleic acid binding
Cluster 37: Non-specific - mRNA processing
Cluster 84: Apical squamous epithelium - Cornification
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Colon Adenocarcinoma", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
9,994
5
ENSG00000157927
RADIL
Rap associating with DIL domain
[ "Q96JH8" ]
7
4797055-4883716
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051776" ]
[ "FLJ10324", "KIAA1849", "RASIP2" ]
[ "Predicted intracellular proteins" ]
[ "Cell adhesion" ]
[ "Developmental protein" ]
[]
[ "Nucleoplasm", "Nuclear membrane" ]
[]
[]
[]
Approved
Approved
null
13
null
null
null
Cluster 25: Non-specific - Transcription
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 108: Fibroblasts - ECM organization
Cluster 67: Testis - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
9,995
8
ENSG00000157933
SKI
SKI proto-oncogene
[ "P12755" ]
1
2227388-2310213
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB010449", "HPA066567" ]
[]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Craniosynostosis", "Disease variant", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[ "Nuclear bodies", "Golgi apparatus" ]
[]
[]
Supported
Approved
null
49
null
null
null
Cluster 15: Non-specific - Transcription
Cluster 37: Non-specific - mRNA processing
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 64: Non-specific - Transcription
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
9,996
2
ENSG00000157954
WIPI2
WD repeat domain, phosphoinositide interacting 2
[ "Q9Y4P8" ]
7
5190196-5233840
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA019852", "HPA021488" ]
[ "ATG18B", "ATG21", "CGI-50", "DKFZP434J154", "DKFZp686P02188", "FLJ12979", "FLJ14217", "FLJ42984" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Autophagy" ]
[]
[ "Disease variant", "Intellectual disability" ]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
13
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 14: Neurons - Synaptic function
Cluster 67: Non-specific - Unknown function
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
9,997
1
ENSG00000157985
AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
[ "Q9UPQ3" ]
2
235494043-236131793
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CENTG2", "GGAP1", "KIAA1099" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Protein transport", "Transport" ]
[ "GTPase activation" ]
[]
[]
[]
[]
[]
null
null
null
11
null
null
Cluster 1: T-cells - Unknown function
Cluster 26: Oligodendrocytes - Mixed function
Cluster 26: Non-specific - Mitochondria & RNA binding
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 42: Retina - Visual perception
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
9,999
3
ENSG00000157992
KRTCAP3
Keratinocyte associated protein 3
[ "Q53RY4" ]
2
27442366-27446481
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047136", "HPA060203" ]
[ "KCP3" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
1
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 6: Non-specific - Immune response
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration
Cluster 60: Stomach - Digestion
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in many
8
1
0
1
[ "Breast Invasive Carcinoma" ]
[]
[ "Breast Invasive Carcinoma" ]
10,000
3
ENSG00000158006
PAFAH2
Platelet activating factor acetylhydrolase 2
[ "Q99487" ]
1
25959767-25998117
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA018157" ]
[ "HSD-PLA2" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Hydrolase", "Transferase" ]
[]
[]
[]
[]
[]
null
Approved
null
null
null
Yes
Cluster 12: Non-specific - Mitochondrial translation
Cluster 11: White matter - Signal transduction
Cluster 49: HMC-1 - Innate immune response
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 51: Lymphoid tissue - Adaptive immune response
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
10,002
5
ENSG00000158014
SLC30A2
Solute carrier family 30 member 2
[ "Q9BRI3" ]
1
26037252-26046118
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA017979" ]
[ "ZNT2" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Antiport", "Ion transport", "Transport", "Zinc transport" ]
[]
[ "Disease variant" ]
[ "Vesicles" ]
[]
[]
[]
Approved
null
null
64
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion
Cluster 8: Pancreas - Proteolysis
Tissue enriched
Detected in some
4
Not detected
Not detected
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
10,004
5
ENSG00000158019
BABAM2
BRISC and BRCA1 A complex member 2
[ "Q9NXR7" ]
2
27889941-28338901
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017926", "HPA048867" ]
[ "BRCC4", "BRCC45", "BRE" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis", "Cell cycle", "Cell division", "DNA damage", "DNA repair", "Mitosis", "Ubl conjugation pathway" ]
[ "Chromatin regulator" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
31
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 14: Neurons - Synaptic function
Cluster 15: Kidney cancer - Membrane components
Cluster 18: Adrenal cortex cells - Steroidogensis
Cluster 4: Adrenal gland - Steroid metabolism
Tissue enriched
Detected in all
5
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Uterine Corpus Endometrial Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
10,005
1
ENSG00000158022
TRIM63
Tripartite motif containing 63
[ "Q969Q1" ]
1
26051301-26068436
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "IRF", "MURF-1", "RNF28", "SMRZ" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Ubl conjugation pathway" ]
[ "Muscle protein", "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
54
null
null
null
null
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 46: Skeletal myocytes - Muscle structure & formation
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enriched
Detected in many
5
Cancer enriched
Detected in single
45
Cancer enriched
Detected in some
6
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,006
1
ENSG00000158023
CFAP251
Cilia and flagella associated protein 251
[ "Q8TBY9" ]
12
121918592-122003927
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA039902", "HPA040005" ]
[ "CaM-IP4", "MGC33630", "WDR66" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mid piece", "End piece" ]
[]
[]
[]
Supported
Supported
null
null
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 17: Choroid plexus - Cilium
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
4
Immune cell enriched
Detected in single
8
4
0
4
[ "Rectum Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma", "Rectum Adenocarcinoma" ]
10,007
3
ENSG00000158042
MRPL17
Mitochondrial ribosomal protein L17
[ "Q9NRX2" ]
11
6680385-6683340
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA043666", "HPA050552" ]
[ "MRP-L26", "RPML26" ]
[ "Essential proteins", "Predicted intracellular proteins", "Ribosomal proteins" ]
[]
[ "Ribonucleoprotein", "Ribosomal protein" ]
[]
[]
[]
[]
[]
null
Uncertain
null
60
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 14: Neurons - Synaptic function
Cluster 23: Non-specific - Transcription
Cluster 17: Non-specific - RNA processing
Cluster 4: Adrenal gland - Steroid metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
10,008
4
ENSG00000158050
DUSP2
Dual specificity phosphatase 2
[ "Q05923" ]
2
96143169-96145440
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA071920" ]
[ "PAC-1" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nuclear membrane" ]
[ "Nucleoplasm" ]
[]
[]
Supported
null
null
4
null
null
Cluster 15: NK-cells - Unknown function
Cluster 29: Forebrain - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity
Cluster 15: Bone marrow - Innate immune response
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[ "Rectum Adenocarcinoma" ]
[]
[ "Rectum Adenocarcinoma" ]
10,009
5
ENSG00000158055
GRHL3
Grainyhead like transcription factor 3
[ "Q8TE85" ]
1
24199558-24364482
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059960" ]
[ "SOM", "TFCP2L4" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Actin filaments", "Primary cilium", "Cytosol" ]
[]
[]
Supported
Enhanced
null
8
null
null
null
Cluster 44: Non-specific - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
9
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Bladder Urothelial Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Lung Adenocarcinoma" ]
10,010
3
ENSG00000158062
UBXN11
UBX domain protein 11
[ "Q5T124" ]
1
26281328-26318363
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028600", "HPA031356" ]
[ "SOC", "SOCI", "UBXD5" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Basal body", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
21
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 17: Choroid plexus - Cilium
Cluster 37: Non-specific - mRNA processing
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in all
4
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
10,011
1
ENSG00000158077
NLRP14
NLR family pyrin domain containing 14
[ "Q86W24" ]
11
7020479-7071526
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039477" ]
[ "CLR11.2", "GC-LRR", "Nalp-iota", "NALP14", "NOD5", "PAN8" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[ "Developmental protein" ]
[]
[ "Cytosol" ]
[]
[]
[]
Uncertain
Approved
null
null
null
null
null
Cluster 13: Oligodendrocytes - Mixed function
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 78: Plasma cells - Antibody production & ER-stress response
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,012
6
ENSG00000158079
PTPDC1
Protein tyrosine phosphatase domain containing 1
[ "A2A3K4" ]
9
94030794-94109856
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA016747", "HPA026832" ]
[ "FLJ37312", "PTP9Q22" ]
[ "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Approved
null
21
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 43: Non-specific - Basic cellular processes
Cluster 91: Pituicytes/FSC - Homeostasis & neuron support
Cluster 3: Oligodendrocytes - Myelination
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in many
7
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe" ]
10,013
7
ENSG00000158089
GALNT14
Polypeptide N-acetylgalactosaminyltransferase 14
[ "Q96FL9" ]
2
30910467-31155202
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030138" ]
[ "FLJ12691", "GalNac-T10", "GalNac-T14" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Glycosyltransferase", "Transferase" ]
[]
[ "Golgi apparatus" ]
[ "Nucleoplasm" ]
[]
[]
Approved
null
null
1
null
null
Cluster 20: Non-specific - DNA binding
Cluster 38: Sub-cortical - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 72: Kidney - Transmembrane transport
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
5
Group enriched
Detected in many
7
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
8
3
2
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
10,014
3
ENSG00000158092
NCK1
NCK adaptor protein 1
[ "P16333" ]
3
136862208-136951606
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB005063", "HPA030766" ]
[ "NCK", "NCKalpha" ]
[ "Predicted intracellular proteins" ]
[ "Translation regulation" ]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Supported
null
136
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 50: Non-specific - Nucleic acid binding
Cluster 63: Non-specific - Protein processing
Cluster 7: Non-specific - Transcription
Cluster 81: Squamous epithelium - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe", "Pancreatic Adenocarcinoma" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
10,015
8
ENSG00000158104
HPD
4-hydroxyphenylpyruvate dioxygenase
[ "P32754" ]
12
121839527-121863596
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038321", "HPA038322" ]
[ "4-HPPD", "4HPPD", "GLOD3", "PPD" ]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Phenylalanine catabolism", "Tyrosine catabolism" ]
[ "Dioxygenase", "Oxidoreductase" ]
[ "Disease variant", "FDA approved drug targets", "Intellectual disability" ]
[ "Nuclear speckles" ]
[]
[]
[]
Uncertain
Enhanced
null
3
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 36: Choroid plexus - Mixed function
Cluster 7: Liver cancer - Metabolism
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 16: Liver & Kidney - Metabolism
Tissue enriched
Detected in many
5
Group enriched
Detected in many
5
Cancer enriched
Detected in many
52
Cell type enriched
Detected in many
7
Immune cell enhanced
Detected in some
null
2
0
2
[]
[ "Glioblastoma Multiforme", "Uterine Corpus Endometrial Carcinoma" ]
[ "Glioblastoma Multiforme", "Uterine Corpus Endometrial Carcinoma" ]
10,016
4
ENSG00000158106
RHPN1
Rhophilin Rho GTPase binding protein 1
[ "Q8TCX5" ]
8
143368876-143384221
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA024288", "HPA024671" ]
[ "KIAA1929", "ODF5", "RHPN" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
19
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 28: Astrocytes - Homeostasis & neuron support
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Lung Squamous Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
10,017
2
ENSG00000158109
TPRG1L
Tumor protein p63 regulated 1 like
[ "Q5T0D9" ]
1
3625015-3630127
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA063163", "CAB079051" ]
[ "FAM79A", "FLJ21811", "h-Mover", "RP11-46F15.3", "SVAP30", "TPRGL" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Plasma membrane" ]
[]
[]
Approved
null
Supported
null
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 24: Neurons - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,018
5
ENSG00000158122
PRXL2C
Peroxiredoxin like 2C
[ "Q7RTV5" ]
9
96639577-96655317
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA021294" ]
[ "AAED1", "C9orf21" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Approved
null
1
null
null
Cluster 32: Basophils - Transcription
Cluster 30: White matter - Myelination
Cluster 43: Non-specific - Basic cellular processes
Cluster 103: Non-specific - Basic cellular processes
Cluster 14: Adipose tissue - Angiogenesis
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Thyroid Carcinoma" ]
10,020
8
ENSG00000158156
XKR8
XK related 8
[ "Q9H6D3" ]
1
27959588-27968093
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA049984", "HPA053529" ]
[ "FLJ10307" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Apoptosis" ]
[]
[]
[ "Golgi apparatus" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 44: Non-specific - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 70: Non-specific - Protein processing
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in all
7
2
0
2
[]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
[ "Glioblastoma Multiforme", "Liver Hepatocellular Carcinoma" ]
10,022
7
ENSG00000158158
CNNM4
Cyclin and CBS domain divalent metal cation transport mediator 4
[ "Q6P4Q7" ]
2
96760902-96811874
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017732" ]
[ "ACDP4", "KIAA1592" ]
[ "Disease related genes", "Human disease related genes", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Biomineralization", "Ion transport", "Sensory transduction", "Transport", "Vision" ]
[]
[ "Amelogenesis imperfecta", "Cone-rod dystrophy", "Disease variant" ]
[ "Actin filaments" ]
[ "Plasma membrane" ]
[]
[]
Uncertain
Enhanced
null
29
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 15: Non-specific - Transcription
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
4
0
4
[ "Rectum Adenocarcinoma" ]
[ "Kidney Chromophobe", "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Chromophobe", "Lung Adenocarcinoma", "Ovary Serous Cystadenocarcinoma", "Rectum Adenocarcinoma" ]
10,023
9
ENSG00000158161
EYA3
EYA transcriptional coactivator and phosphatase 3
[ "Q99504" ]
1
27970344-28088637
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA052432", "HPA062889" ]
[ "DKFZp686C132" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair", "Transcription", "Transcription regulation" ]
[ "Activator", "Chromatin regulator", "Developmental protein", "Hydrolase", "Protein phosphatase" ]
[]
[ "Nucleoplasm" ]
[ "Centrosome" ]
[]
[]
Enhanced
Uncertain
null
11
Yes
No
Cluster 16: Non-specific - Cell proliferation
Cluster 50: Non-specific - Nucleic acid binding
Cluster 46: Lymphoma - Humoral immune response
Cluster 50: Renal epithelial cells - Ion transport and pH regulation
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,024
3
ENSG00000158163
DZIP1L
DAZ interacting zinc finger protein 1 like
[ "Q8IYY4" ]
3
138061990-138115818
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA030404" ]
[ "DZIP2", "FLJ32844" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Ciliopathy", "Disease variant" ]
[ "Microtubules", "Cytokinetic bridge", "Mitotic spindle", "Primary cilium", "Basal body" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
Approved
Approved
null
13
Yes
No
null
Cluster 50: Non-specific - Nucleic acid binding
Cluster 3: Rhabdoid - Membrane components
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,025
8
ENSG00000158164
TMSB15A
Thymosin beta 15A
[ "P0CG34" ]
X
102513682-102516739
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "TMSL8", "TMSNB" ]
[ "Predicted intracellular proteins" ]
[]
[ "Actin-binding" ]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 15: NK-cells - Unknown function
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 61: Non-specific - Transcription
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Kidney Chromophobe", "Stomach Adenocarcinoma" ]
[ "Kidney Chromophobe", "Stomach Adenocarcinoma" ]
10,026
1
ENSG00000158169
FANCC
FA complementation group C
[ "Q00597" ]
9
95099054-95426796
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB017793", "HPA030771" ]
[ "FA3", "FAC", "FACC" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "DNA damage", "DNA repair" ]
[]
[ "Cancer-related genes", "Disease variant", "Fanconi anemia" ]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Approved
null
48
null
null
Cluster 32: Basophils - Transcription
Cluster 25: Non-specific - Transcription
Cluster 43: Non-specific - Basic cellular processes
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
7
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,027
2
ENSG00000158186
MRAS
Muscle RAS oncogene homolog
[ "O14807" ]
3
138347648-138405534
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA042728" ]
[ "M-RAs", "R-RAS3", "RRAS3" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Potential drug targets", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[]
[ "Hydrolase" ]
[ "Disease variant" ]
[ "Cytosol" ]
[ "Vesicles" ]
[]
[]
Approved
Approved
null
7
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 19: Astrocytes - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 89: Adipocytes - Lipid metabolism
Cluster 41: Striated muscle - Muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
6
0
0
0
[]
[]
[]
10,028
7
ENSG00000158195
WASF2
WASP family member 2
[ "Q9Y6W5" ]
1
27404230-27490167
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB022632", "HPA045288" ]
[ "SCAR2", "WAVE2" ]
[ "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[ "Actin-binding" ]
[]
[ "Plasma membrane" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
74
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 19: Astrocytes - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 81: Squamous epithelium - Keratinization
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
10,029
3
ENSG00000158220
ESYT3
Extended synaptotagmin 3
[ "A0FGR9" ]
3
138434586-138481686
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA039200" ]
[ "CHR3SYT", "FAM62C" ]
[ "Predicted membrane proteins", "Transporters" ]
[ "Lipid transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
2
null
null
null
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 29: Non-specific - Unknown function
Cluster 81: Alveolar cells - Lung function
Cluster 2: Non-specific - Mixed function
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in single
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
10,031
4
ENSG00000158234
FAIM
Fas apoptotic inhibitory molecule
[ "Q9NVQ4" ]
3
138608606-138633376
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042440", "HPA052209" ]
[ "FAIM1", "FLJ10582" ]
[ "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
3
null
null
Cluster 32: Basophils - Transcription
Cluster 28: Oligodendrocytes - Mixed function
Cluster 35: RS4;11 - Unknown function
Cluster 79: Photoreceptor cells - Phototransduction
Cluster 42: Retina - Visual perception
Tissue enriched
Detected in all
6
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,032
9
ENSG00000158246
TENT5B
Terminal nucleotidyltransferase 5B
[ "Q96A09" ]
1
27005020-27012850
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "FAM46B", "MGC16491" ]
[ "Enzymes", "Predicted intracellular proteins" ]
[]
[ "Nucleotidyltransferase", "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
64
null
null
null
Cluster 37: Neurons - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
10,033
4
ENSG00000158258
CLSTN2
Calsyntenin 2
[ "Q9H4D0" ]
3
139935185-140577397
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA031342", "HPA061800" ]
[ "CDHR13", "CS2", "CSTN2", "FLJ39113" ]
[ "Predicted membrane proteins" ]
[ "Cell adhesion" ]
[]
[]
[ "Vesicles" ]
[ "Cytokinetic bridge" ]
[]
[]
Uncertain
Approved
null
null
Yes
No
null
Cluster 51: Neurons - Mixed function
Cluster 12: Bone cancer - Neuronal signaling
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Group enriched
Detected in many
5
Group enriched
Detected in many
5
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,034
4
ENSG00000158270
COLEC12
Collectin subfamily member 12
[ "Q5KU26" ]
18
316737-500722
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047917", "HPA071056" ]
[ "CL-P1", "SCARA4", "SRCL" ]
[ "Predicted membrane proteins" ]
[]
[ "Receptor" ]
[]
[ "Golgi apparatus", "Vesicles" ]
[ "Cell Junctions" ]
[]
[]
Approved
Enhanced
null
6
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 5: Rhabdoid - Unknown function
Cluster 72: Macrophages - Phagocytosis & lysosomal degradation
Cluster 14: Adipose tissue - Angiogenesis
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Bladder Urothelial Carcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
10,035
6
ENSG00000158286
RNF207
Ring finger protein 207
[ "Q6ZRF8" ]
1
6205475-6221299
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA028378", "HPA042535" ]
[ "C1orf188", "FLJ32096", "FLJ46380" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
1
null
null
null
Cluster 23: Choroid plexus - Mixed function
Cluster 56: Non-specific - Sensory perception
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
Cluster 35: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,036
8
ENSG00000158290
CUL4B
Cullin 4B
[ "Q13620" ]
X
120505920-120604074
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003046", "HPA011880", "CAB017786", "HPA058979" ]
[]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "DNA damage", "DNA repair", "Ubl conjugation pathway" ]
[]
[ "Cancer-related genes", "Disease variant", "Dwarfism", "Intellectual disability" ]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Enhanced
null
190
null
null
Cluster 30: Non-specific - DNA binding
Cluster 31: Non-specific - Transcription
Cluster 36: Non-specific - mRNA processing
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
10,037
3
ENSG00000158292
GPR153
G protein-coupled receptor 153
[ "Q6NV75" ]
1
6247353-6261098
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA007159" ]
[ "PGR1" ]
[ "G-protein coupled receptors", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[]
[]
[]
[]
[]
null
Approved
null
null
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 2: Mucus-secreting cells - Unknown function
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
[ "Lung Adenocarcinoma", "Lung Squamous Cell Carcinoma" ]
10,038
1
ENSG00000158296
SLC13A3
Solute carrier family 13 member 3
[ "Q8WWT9" ]
20
46557823-46684467
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA014333", "HPA014353", "HPA014736" ]
[ "NADC3", "SDCT2" ]
[ "Disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted membrane proteins", "Transporters" ]
[ "Ion transport", "Lipid transport", "Sodium transport", "Symport", "Transport" ]
[]
[ "Disease variant" ]
[ "Plasma membrane" ]
[]
[]
[]
Supported
Enhanced
null
9
null
null
null
Cluster 13: Oligodendrocytes - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 88: Proximal tubular cells - Transmembrane transport
Cluster 72: Kidney - Transmembrane transport
Tissue enriched
Detected in many
9
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
4
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Skin Cutaneous Melanoma" ]
[ "Skin Cutaneous Melanoma" ]
10,039
3
ENSG00000158301
GPRASP2
G protein-coupled receptor associated sorting protein 2
[ "Q96D09" ]
X
102712445-102717733
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017438" ]
[ "FLJ37327", "GASP2" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Deafness", "Disease variant" ]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
33
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 98: Neurons - Neurotransmission & signaling
Cluster 65: Brain - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Group enriched
Detected in some
4
Immune cell enhanced
Detected in single
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,040
2
ENSG00000158315
RHBDL2
Rhomboid like 2
[ "Q9NX52" ]
1
38885807-38941830
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA043807" ]
[ "FLJ20435" ]
[ "Enzymes", "Predicted membrane proteins" ]
[]
[ "Hydrolase", "Protease", "Serine protease" ]
[]
[]
[]
[]
[]
null
Approved
null
1
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 6: Non-specific - Immune response
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
3
0
3
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Rectum Adenocarcinoma" ]
10,041
1
ENSG00000158321
AUTS2
Activator of transcription and developmental regulator AUTS2
[ "Q8WXX7" ]
7
69598296-70793506
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000390" ]
[ "FBRSL2", "KIAA0442" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[]
[ "Autism", "Autism spectrum disorder", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Plasma membrane", "Cell Junctions", "Cytosol" ]
[]
[]
Supported
Approved
null
21
Yes
No
Cluster 14: Non-specific - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 6: Leukemia - Signal transduction
Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling
Cluster 2: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,042
1