ensembl_id
string
gene
string
gene_description
string
uniprot
list
chromosome
string
position
string
evidence
string
hpa_evidence
string
uniprot_evidence
string
nextprot_evidence
string
antibodies
list
gene_synonyms
list
protein_classes
list
biological_processes
list
molecular_functions
list
disease_involvement
list
subcellular_main_locations
list
subcellular_additional_locations
list
secretome_locations
list
secretome_functions
list
reliability_if
string
reliability_ih
string
reliability_mouse_brain
string
interactions
float64
ccd_protein
string
ccd_transcript
string
blood_expression_cluster
string
brain_expression_cluster
string
cell_line_expression_cluster
string
single_cell_expression_cluster
string
tissue_expression_cluster
string
rna_tissue_specificity
string
rna_tissue_distribution
string
rna_tissue_specificity_score
float64
rna_cell_line_specificity
string
rna_cell_line_distribution
string
rna_cell_line_specificity_score
float64
rna_cancer_specificity
string
rna_cancer_distribution
string
rna_cancer_specificity_score
float64
rna_single_cell_type_specificity
string
rna_single_cell_type_distribution
string
rna_single_cell_type_specificity_score
float64
rna_blood_cell_specificity
string
rna_blood_cell_distribution
string
rna_blood_cell_specificity_score
float64
prognostic_cancer_count
int64
validated_prognostic_cancer_count
int64
potential_prognostic_cancer_count
int64
favorable_prognostic_cancers
list
unfavorable_prognostic_cancers
list
prognostic_cancers
list
source_row_index
int64
split_bucket
int64
ENSG00000159208
CIART
Circadian associated repressor of transcription
[ "Q8N365" ]
1
150282543-150287093
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA027515", "HPA054349" ]
[ "BC017397", "C1orf51", "CHRONO" ]
[ "Predicted intracellular proteins" ]
[ "Biological rhythms", "Transcription", "Transcription regulation" ]
[ "Repressor" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Enhanced
null
7
null
null
Cluster 31: T-cells - T-cell receptor
Cluster 15: Non-specific - Transcription
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
10,149
8
ENSG00000159210
SNF8
SNF8 subunit of ESCRT-II
[ "Q96H20" ]
17
48929316-48944842
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA059320" ]
[ "Dot3", "EAP30", "VPS22" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Protein transport", "Transcription", "Transcription regulation", "Transport" ]
[]
[ "Disease variant", "Epilepsy", "Intellectual disability" ]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Supported
Approved
null
44
null
null
Cluster 29: Non-specific - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 97: Non-specific - Cellular respiration
Cluster 52: Non-specific - Cellular respiration
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,150
7
ENSG00000159212
CLIC6
Chloride intracellular channel 6
[ "Q96NY7" ]
21
34668994-34718227
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA065285" ]
[ "CLIC1L", "CLIC5" ]
[ "Predicted intracellular proteins", "Transporters" ]
[ "Ion transport", "Transport" ]
[ "Chloride channel", "Ion channel", "Oxidoreductase", "Voltage-gated channel" ]
[]
[]
[]
[]
[]
null
Enhanced
null
4
null
null
null
Cluster 36: Choroid plexus - Mixed function
Cluster 27: Breast cancer - Unknown function
Cluster 101: Choroid plexus epithelial cells - Ion transport
Cluster 1: Choroid plexus - Transmembrane transport
Group enriched
Detected in many
10
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Not detected in immune cells
Not detected
null
4
0
4
[ "Breast Invasive Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Glioblastoma Multiforme" ]
[ "Breast Invasive Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Papillary Cell Carcinoma", "Lung Adenocarcinoma" ]
10,151
7
ENSG00000159214
CCDC24
Coiled-coil domain containing 24
[ "Q8N4L8" ]
1
43991359-43996528
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA035424", "HPA061710" ]
[ "MGC45441" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane" ]
[ "Nucleoli", "Cytosol" ]
[]
[]
Approved
Uncertain
null
30
null
null
Cluster 29: Non-specific - Unknown function
Cluster 23: Choroid plexus - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 96: Enteroendocrine cells - Neuropeptide signaling
Cluster 48: Ciliated tissues - Cilium organization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Group enriched
Detected in some
5
2
0
2
[ "Breast Invasive Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,152
6
ENSG00000159216
RUNX1
RUNX family transcription factor 1
[ "Q01196" ]
21
34787801-36004667
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004176", "HPA037912" ]
[ "AML1", "AMLCR1", "CBFA2", "PEBP2A2" ]
[ "Cancer-related genes", "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "Activator", "DNA-binding", "Repressor" ]
[ "Cancer-related genes", "Disease variant", "Proto-oncogene" ]
[ "Nucleoplasm" ]
[ "Vesicles" ]
[]
[]
Enhanced
Enhanced
null
58
No
No
Cluster 22: Eosinophils - Transcription
Cluster 20: Macrophages & Microglia - Immune response
Cluster 6: Leukemia - Signal transduction
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
10,153
6
ENSG00000159217
IGF2BP1
Insulin like growth factor 2 mRNA binding protein 1
[ "Q9NZI8" ]
17
48997385-49056145
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021367", "HPA062273" ]
[ "IMP-1" ]
[ "Predicted intracellular proteins" ]
[ "mRNA transport", "Translation regulation", "Transport" ]
[ "RNA-binding" ]
[]
[ "Cytosol" ]
[]
[]
[]
Supported
Enhanced
null
166
null
null
null
null
Cluster 34: Testis cancer - Unknown function
Cluster 108: Fibroblasts - ECM organization
Cluster 43: Placenta - Pregnancy hormone signaling
Group enriched
Detected in some
4
Cancer enhanced
Detected in many
null
Cancer enriched
Detected in many
19
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
3
0
3
[]
[ "Bladder Urothelial Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
10,154
4
ENSG00000159224
GIP
Gastric inhibitory polypeptide
[ "P09681" ]
17
48958554-48968596
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021612", "HPA064596" ]
[]
[ "FDA approved drug targets", "Plasma proteins", "Predicted secreted proteins" ]
[]
[ "Hormone" ]
[ "FDA approved drug targets" ]
[]
[]
[ "Secreted to blood" ]
[ "Hormone" ]
null
Enhanced
null
15
null
null
null
null
Cluster 1: Neuronal - Visual perception
Cluster 96: Enteroendocrine cells - Neuropeptide signaling
Cluster 7: Small intestine - Absorption and Digestion
Tissue enriched
Detected in some
209
Cancer enhanced
Detected in single
null
Cancer enriched
Detected in some
53
Cell type enriched
Detected in some
80
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,155
8
ENSG00000159228
CBR1
Carbonyl reductase 1
[ "P16152" ]
21
36069941-36073166
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018433", "CAB034291" ]
[ "CBR", "SDR21C1" ]
[ "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Lipid metabolism" ]
[ "Oxidoreductase" ]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
24
null
null
Cluster 25: Non-specific - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 7: Liver cancer - Metabolism
Cluster 1: Enterocytes - Absorption and Digestion
Cluster 1: Choroid plexus - Transmembrane transport
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Glioblastoma Multiforme" ]
[ "Glioblastoma Multiforme" ]
10,156
1
ENSG00000159248
GJD2
Gap junction protein delta 2
[ "Q9UKL4" ]
15
34751032-34754998
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "CX36", "GJA9" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
1
null
null
null
Cluster 24: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 76: Pancreatic endocrine cells - Endocrine signaling
Cluster 46: Brain & retina - Neuronal signaling
Tissue enhanced
Detected in some
null
Group enriched
Detected in some
4
Group enriched
Detected in some
17
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,158
7
ENSG00000159251
ACTC1
Actin alpha cardiac muscle 1
[ "P68032" ]
15
34790230-34795549
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB037330", "HPA041264", "HPA041271" ]
[ "ACTC", "CMD1R" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Hydrolase", "Muscle protein" ]
[ "Atrial septal defect", "Cardiomyopathy", "Disease variant" ]
[]
[]
[]
[]
null
Enhanced
null
107
null
null
null
Cluster 49: Hindbrain - Mixed function
Cluster 33: Sarcoma - Muscle contraction
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 35: Non-specific - Mixed function
Tissue enriched
Detected in many
16
Cancer enriched
Detected in many
9
Cancer enhanced
Detected in many
null
Group enriched
Detected in some
8
Not detected in immune cells
Not detected
null
2
0
2
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
10,159
6
ENSG00000159256
MORC3
MORC family CW-type zinc finger 3
[ "Q14149" ]
21
36320189-36386148
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA018406", "HPA034848" ]
[ "KIAA0136", "NXP2", "ZCW5", "ZCWCC3" ]
[ "Predicted intracellular proteins" ]
[ "Host-virus interaction", "Immunity", "Innate immunity" ]
[ "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Mitochondria" ]
[]
[]
Enhanced
Approved
null
16
null
null
Cluster 42: Non-specific - Vesicular transport
Cluster 55: Non-specific - Transcription
Cluster 47: Leukemia - Hemostasis
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,160
9
ENSG00000159259
CHAF1B
Chromatin assembly factor 1 subunit B
[ "Q13112" ]
21
36385392-36419015
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021679", "CAB033604" ]
[ "CAF-1", "CAF1", "CAF1A", "CAF1P60", "MPHOSPH7", "MPP7" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell cycle", "DNA damage", "DNA repair", "DNA replication" ]
[ "Chaperone", "Chromatin regulator" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Supported
Enhanced
null
57
null
Yes
Cluster 3: Non-specific - Nuclear processes
Cluster 48: Non-specific - Mixed function
Cluster 47: Leukemia - Hemostasis
Cluster 27: Non-specific - Cell proliferation
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
4
6
1
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma" ]
10,161
6
ENSG00000159261
CLDN14
Claudin 14
[ "O95500" ]
21
36460621-36576569
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA054707" ]
[ "DFNB29" ]
[ "Disease related genes", "Human disease related genes", "Predicted membrane proteins" ]
[]
[]
[ "Deafness", "Disease variant", "Non-syndromic deafness" ]
[ "Vesicles" ]
[]
[]
[]
Uncertain
null
null
4
null
null
null
Cluster 32: Cerebral cortex - Mixed function
Cluster 21: Lymphoma - Adaptive immune response
Cluster 50: Renal epithelial cells - Ion transport and pH regulation
Cluster 31: Liver - Metabolism & Coagulation
Tissue enriched
Detected in some
5
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
4
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,162
2
ENSG00000159263
SIM2
SIM bHLH transcription factor 2
[ "Q14190" ]
21
36699115-36749917
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA029295" ]
[ "bHLHe15", "MGC119447", "SIM" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Differentiation", "Neurogenesis", "Transcription", "Transcription regulation" ]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Nucleoplasm", "Nuclear bodies" ]
[]
[]
[]
Supported
Approved
null
5
No
No
null
Cluster 29: Forebrain - Mixed function
Cluster 60: Prostate cancer - Unknown function
Cluster 50: Renal epithelial cells - Ion transport and pH regulation
Cluster 72: Kidney - Transmembrane transport
Group enriched
Detected in some
5
Cancer enhanced
Detected in many
null
Group enriched
Detected in many
4
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma", "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
10,163
7
ENSG00000159267
HLCS
Holocarboxylase synthetase
[ "P50747" ]
21
36748626-36990236
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA017379" ]
[ "HCS" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[]
[ "Ligase", "Multifunctional enzyme" ]
[ "Disease variant" ]
[ "Cytosol" ]
[]
[]
[]
Approved
Approved
null
12
null
null
Cluster 30: Non-specific - DNA binding
Cluster 50: Non-specific - Nucleic acid binding
Cluster 70: DU4475 - Unknown function
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 38: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
1
0
1
[]
[ "Breast Invasive Carcinoma" ]
[ "Breast Invasive Carcinoma" ]
10,164
9
ENSG00000159289
GOLGA6A
Golgin A6 family member A
[ "Q9NYA3" ]
15
74069857-74082550
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044978", "HPA050087", "HPA072134" ]
[ "GLP", "GOLGA6" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[ "Nucleoplasm", "Centrosome" ]
[]
[]
Approved
Supported
null
39
null
null
null
null
Cluster 33: Sarcoma - Muscle contraction
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 47: Testis - Mixed function
Tissue enriched
Detected in some
6
Not detected
Not detected
null
Not detected
Not detected
null
Group enriched
Detected in some
12
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,165
7
ENSG00000159314
ARHGAP27
Rho GTPase activating protein 27
[ "Q6ZUM4" ]
17
45393902-45434421
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA023919", "HPA053053" ]
[ "CAMGAP1", "FLJ43547", "SH3D20", "SH3P20" ]
[ "Predicted intracellular proteins" ]
[ "Endocytosis" ]
[ "GTPase activation" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Enhanced
null
2
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 38: Sub-cortical - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 102: Non-specific - Mixed function
Cluster 81: Squamous epithelium - Keratinization
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Colon Adenocarcinoma" ]
[]
[ "Colon Adenocarcinoma" ]
10,167
5
ENSG00000159322
ADPGK
ADP dependent glucokinase
[ "Q9BRR6" ]
15
72751294-72785846
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA045194", "HPA058525" ]
[ "ADP-GK", "DKFZp434B195" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Glycolysis" ]
[ "Kinase", "Transferase" ]
[]
[ "Centrosome" ]
[]
[ "Intracellular and membrane" ]
[ "Enzyme" ]
Approved
Approved
null
2
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 44: Non-specific - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 66: Lymphoid tissue - Immune response
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,168
6
ENSG00000159335
PTMS
Parathymosin
[ "P20962" ]
12
6765516-6770952
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038186" ]
[ "ParaT" ]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Immunity" ]
[]
[]
[ "Nucleoli", "Nucleoli rim" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
4
No
Yes
Cluster 22: Eosinophils - Transcription
Cluster 33: Neurons - Mixed function
Cluster 38: Non-specific - Transcription
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
6
0
0
0
[]
[]
[]
10,169
6
ENSG00000159337
PLA2G4D
Phospholipase A2 group IVD
[ "Q86XP0" ]
15
42067009-42094562
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA074206" ]
[ "cPLA2delta" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[ "Lipid degradation", "Lipid metabolism" ]
[ "Hydrolase" ]
[]
[ "Cytosol" ]
[ "Plasma membrane" ]
[]
[]
Approved
null
null
null
null
null
null
Cluster 29: Forebrain - Mixed function
Cluster 32: Non-specific - Cell proliferation
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 58: Skin - Keratinization
Group enriched
Detected in some
11
Not detected
Not detected
null
Group enriched
Detected in some
4
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,170
4
ENSG00000159339
PADI4
Peptidyl arginine deiminase 4
[ "Q9UM07" ]
1
17308195-17364004
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA017007", "HPA042825" ]
[ "PAD", "PADI5", "PDI4", "PDI5" ]
[ "Disease related genes", "Enzymes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Immunity", "Innate immunity", "Transcription", "Transcription regulation" ]
[ "Chromatin regulator", "Hydrolase" ]
[]
[]
[]
[]
[]
null
Enhanced
null
15
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 53: Neurons - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 15: Bone marrow - Innate immune response
Group enriched
Detected in some
8
Cancer enriched
Detected in single
10
Not detected
Not detected
null
Group enriched
Detected in some
7
Group enriched
Detected in many
8
0
0
0
[]
[]
[]
10,171
1
ENSG00000159346
ADIPOR1
Adiponectin receptor 1
[ "Q96A54" ]
1
202940826-202958572
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "ACDCR1", "PAQR1" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Fatty acid metabolism", "Lipid metabolism" ]
[ "Receptor" ]
[]
[]
[]
[]
[]
null
null
null
3
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 36: Choroid plexus - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 84: Apical squamous epithelium - Cornification
Cluster 63: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,172
8
ENSG00000159348
CYB5R1
Cytochrome b5 reductase 1
[ "Q9UHQ9" ]
1
202961873-202967275
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA010531", "HPA010641", "HPA014147" ]
[ "humb5R2", "NQO3A2" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Lipid biosynthesis", "Lipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism" ]
[ "Oxidoreductase" ]
[]
[ "Mitochondria" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
15
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func.
Cluster 19: Skeletal muscle - Striated muscle contraction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Rectum Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Rectum Adenocarcinoma" ]
10,173
8
ENSG00000159352
PSMD4
Proteasome 26S subunit ubiquitin receptor, non-ATPase 4
[ "P55036" ]
1
151254709-151267479
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA038807", "HPA039252", "CAB047300" ]
[ "AF", "AF-1", "Rpn10", "S5A" ]
[ "Cancer-related genes", "Essential proteins", "Predicted intracellular proteins" ]
[]
[]
[ "Cancer-related genes" ]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Approved
Enhanced
null
211
null
null
Cluster 25: Non-specific - Unknown function
Cluster 45: Non-specific - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
10,174
5
ENSG00000159363
ATP13A2
ATPase cation transporting 13A2
[ "Q9NQ11" ]
1
16985958-17011928
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB037038", "CAB037111", "HPA050910", "HPA054717" ]
[ "CLN12", "HSA9947", "PARK9" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Transport" ]
[ "Translocase" ]
[ "Disease variant", "Hereditary spastic paraplegia", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Parkinsonism" ]
[]
[]
[]
[]
null
Enhanced
null
21
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
Cluster 1: Neurons - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 109: Neurons - Neuronal signaling
Cluster 36: Brain & Liver - Signaling
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in many
6
4
0
4
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,175
6
ENSG00000159374
M1AP
Meiosis 1 associated protein
[ "Q8TC57" ]
2
74557883-74648338
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA045420", "HPA059302" ]
[ "C2orf65", "D6Mm5e", "SPATA37" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[]
[ "Disease variant" ]
[ "Mitochondria" ]
[ "Nucleoli" ]
[]
[]
Approved
Uncertain
null
11
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 15: Kidney cancer - Membrane components
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 56: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,176
9
ENSG00000159377
PSMB4
Proteasome 20S subunit beta 4
[ "P28070" ]
1
151399560-151401937
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006700", "HPA073499" ]
[ "HN3", "PROS26" ]
[ "Disease related genes", "Enzymes", "Essential proteins", "Human disease related genes", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[]
[ "Disease variant" ]
[ "Nucleoplasm" ]
[ "Mitochondria" ]
[]
[]
Supported
Approved
null
162
null
null
Cluster 13: Non-specific - Mitochondria
Cluster 27: Non-specific - Mixed function
Cluster 45: Non-specific - Nuclear processes
Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Breast Invasive Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,177
7
ENSG00000159387
IRX6
Iroquois homeobox 6
[ "P78412" ]
16
55324203-55330756
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA018332" ]
[ "IRX-3", "IRX7" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "DNA-binding" ]
[]
[ "Nucleoplasm", "Mitochondria" ]
[]
[]
[]
Approved
Uncertain
null
9
null
null
null
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 16: Thyroid cancer - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 58: Skin - Keratinization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Lung Adenocarcinoma" ]
[]
[ "Lung Adenocarcinoma" ]
10,178
4
ENSG00000159388
BTG2
BTG anti-proliferation factor 2
[ "P78543" ]
1
203305491-203309602
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA002355" ]
[ "APRO1", "MGC126063", "MGC126064", "PC3", "TIS21" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[]
[ "Cancer-related genes" ]
[ "Vesicles" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Uncertain
null
11
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 51: Myeloma - Immunoglobulins
Cluster 31: Neutrophils - Chemotaxis & Apoptosis
Cluster 8: Pancreas - Proteolysis
Low tissue specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
10,179
4
ENSG00000159398
CES5A
Carboxylesterase 5A
[ "Q6NT32" ]
16
55846154-55956031
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[]
[ "CAUXIN", "CES4C1", "CES5", "CES7", "FLJ31547" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Hydrolase", "Serine esterase" ]
[]
[]
[]
[ "Secreted in male reproductive system" ]
[ "Enzyme" ]
null
null
null
null
null
null
null
Cluster 30: White matter - Myelination
Cluster 51: Myeloma - Immunoglobulins
Cluster 10: Epididymal principal cells - Sperm maturation microenvironment
Cluster 50: Epididymis - Male reproductive secretion
Tissue enriched
Detected in some
17
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enriched
Detected in some
6
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
10,180
2
ENSG00000159399
HK2
Hexokinase 2
[ "P52789" ]
2
74834127-74893359
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028587", "HPA061711" ]
[]
[ "Cancer-related genes", "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Glycolysis" ]
[ "Allosteric enzyme", "Kinase", "Transferase" ]
[ "Cancer-related genes" ]
[ "Mitochondria", "Cytosol" ]
[ "Vesicles", "Centrosome" ]
[]
[]
Supported
Enhanced
null
19
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 30: White matter - Myelination
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
0
3
[ "Colon Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Colon Adenocarcinoma", "Liver Hepatocellular Carcinoma" ]
10,181
8
ENSG00000159403
C1R
Complement C1r
[]
12
7080214-7092540
Evidence at transcript level
Evidence at transcript level
null
null
[ "HPA001251", "HPA001551" ]
[]
[ "Human disease related genes", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Uncertain
Uncertain
null
1
null
null
Cluster 11: T-cells - Unknown function
Cluster 39: Astrocytes - Mixed function
Cluster 44: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 31: Liver - Metabolism & Coagulation
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
2
0
2
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,182
8
ENSG00000159409
CELF3
CUGBP Elav-like family member 3
[ "Q5SZQ8" ]
1
151700058-151716803
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA006292" ]
[ "BRUNOL1", "CAGH4", "ERDA4", "MGC57297", "TNRC4" ]
[ "Predicted intracellular proteins" ]
[ "mRNA processing", "mRNA splicing" ]
[ "Activator", "RNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
null
Cluster 51: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 86: Retinal bipolar cells - Synaptic signal transduction
Cluster 27: Cerebellum - Synaptic function
Group enriched
Detected in some
5
Cancer enriched
Detected in some
7
Group enriched
Detected in many
4
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,183
6
ENSG00000159423
ALDH4A1
Aldehyde dehydrogenase 4 family member A1
[ "P30038" ]
1
18871430-18902724
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004645", "HPA006401", "HPA072759" ]
[ "ALDH4", "P5CDh" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Proline metabolism" ]
[ "Oxidoreductase" ]
[ "Disease variant" ]
[ "Mitochondria" ]
[]
[]
[]
Supported
Enhanced
null
18
null
null
Cluster 2: Dendritic cells - Unknown function
Cluster 42: Choroid plexus - Mitochondria
Cluster 70: DU4475 - Unknown function
Cluster 93: Hepatocytes - Bile production & excretion
Cluster 16: Liver & Kidney - Metabolism
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enriched
Detected in many
4
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
10,184
9
ENSG00000159433
STARD9
StAR related lipid transfer domain containing 9
[ "Q9P2P6" ]
15
42575606-42720998
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA014562" ]
[ "KIAA1300", "KIF16A" ]
[ "Metabolic proteins", "Predicted intracellular proteins" ]
[]
[ "Motor protein" ]
[]
[]
[]
[]
[]
null
Uncertain
null
3
null
null
null
Cluster 11: White matter - Signal transduction
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 47: Testis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,185
9
ENSG00000159445
THEM4
Thioesterase superfamily member 4
[ "Q5T1C6" ]
1
151870866-151909637
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA028161" ]
[ "CTMP" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins" ]
[ "Apoptosis", "Fatty acid metabolism", "Lipid metabolism" ]
[ "Hydrolase" ]
[]
[]
[]
[]
[]
null
Approved
null
10
null
null
Cluster 39: T-cells - T-cell receptor
Cluster 26: Oligodendrocytes - Mixed function
Cluster 69: Skin cancer - ECM organization
Cluster 9: T-cells - Adaptive immunity: Regulation
Cluster 42: Retina - Visual perception
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Chromophobe", "Liver Hepatocellular Carcinoma" ]
10,186
3
ENSG00000159450
TCHH
Trichohyalin
[ "Q07283" ]
1
152106317-152115444
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA028375" ]
[ "THH" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Keratinization" ]
[]
[]
[]
[]
[]
[]
null
Approved
null
2
null
null
null
null
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in some
18
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in some
null
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,187
7
ENSG00000159455
LCE2B
Late cornified envelope 2B
[ "O14633" ]
1
152686123-152687397
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "LEP10", "SPRL1B", "XP5" ]
[ "Predicted intracellular proteins" ]
[ "Keratinization" ]
[]
[]
[]
[]
[]
[]
null
null
null
56
null
null
null
null
Cluster 64: Connective tissue cells - ECM organization
Cluster 103: Non-specific - Basic cellular processes
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in some
19
Cancer enriched
Detected in single
14
Cancer enriched
Detected in some
5
Not detected
Not detected
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,188
8
ENSG00000159461
AMFR
Autocrine motility factor receptor
[ "Q9UKV5" ]
16
56361452-56425545
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB026381", "HPA029018", "HPA064339", "HPA077835" ]
[ "gp78", "RNF45" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "Ubl conjugation pathway", "Wnt signaling pathway" ]
[ "Receptor", "Transferase" ]
[ "Disease variant", "Hereditary spastic paraplegia", "Neurodegeneration" ]
[ "Endoplasmic reticulum", "Golgi apparatus" ]
[]
[]
[]
Supported
Approved
null
105
null
null
Cluster 14: Non-specific - Unknown function
Cluster 21: Non-specific - Metabolism
Cluster 46: Lymphoma - Humoral immune response
Cluster 47: Platelets - Hemostasis
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
0
0
0
[]
[]
[]
10,190
1
ENSG00000159479
MED8
Mediator complex subunit 8
[ "Q96G25" ]
1
43383917-43389808
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA028377", "HPA028438" ]
[ "ARC32", "MGC17544", "MGC19641" ]
[ "Essential proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation", "Ubl conjugation pathway" ]
[ "Activator" ]
[]
[ "Nucleoplasm" ]
[ "Golgi apparatus" ]
[]
[]
Approved
Approved
null
94
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 27: Non-specific - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,191
5
ENSG00000159495
TGM7
Transglutaminase 7
[ "Q96PF1" ]
15
43276271-43302255
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "TGMZ" ]
[ "Cancer-related genes", "Enzymes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[]
[ "Acyltransferase", "Transferase" ]
[ "Cancer-related genes" ]
[]
[]
[]
[]
null
null
null
15
null
null
null
null
Cluster 15: Kidney cancer - Membrane components
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 39: Testis - Nuclear processes
Tissue enhanced
Detected in single
null
Not detected
Not detected
null
Cancer enriched
Detected in single
12
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,192
5
ENSG00000159496
RGL4
Ral guanine nucleotide dissociation stimulator like 4
[ "Q8IZJ4" ]
22
23688136-23699176
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
[ "HPA035979" ]
[ "Rgr" ]
[ "Predicted intracellular proteins" ]
[]
[ "Guanine-nucleotide releasing factor" ]
[]
[ "Centrosome" ]
[]
[ "Intracellular and membrane" ]
[ "Other" ]
Approved
Uncertain
null
1
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 48: Non-specific - Mixed function
Cluster 14: Myeloid leukemia - Innate immune response
Cluster 48: Neutrophils - Phagocytosis & degranulation
Cluster 15: Bone marrow - Innate immune response
Tissue enriched
Detected in many
8
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
5
Immune cell enhanced
Detected in many
null
4
0
4
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Head and Neck Squamous Cell Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
10,193
2
ENSG00000159516
SPRR2G
Small proline rich protein 2G
[ "Q9BYE4" ]
1
153149582-153150890
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Evidence at protein level
[]
[]
[ "Essential proteins", "Predicted intracellular proteins" ]
[ "Keratinization" ]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 9: Skin - Hair follicle development
Tissue enriched
Detected in some
35
Cancer enriched
Detected in some
8
Group enriched
Detected in many
13
Cell type enriched
Detected in some
4
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,194
4
ENSG00000159556
ISL2
ISL LIM homeobox 2
[ "Q96A47" ]
15
76336773-76342475
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA075192" ]
[ "FLJ10160" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[]
[ "Developmental protein", "DNA-binding" ]
[]
[ "Rods & Rings" ]
[]
[]
[]
Approved
null
null
15
null
null
Cluster 28: Neutrophils - Unknown function
Cluster 11: White matter - Signal transduction
Cluster 1: Neuronal - Visual perception
Cluster 67: Plasma cells - Plasma cell differentiation
Cluster 11: Esophagus - Basic cellular processes
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in some
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
10,196
9
ENSG00000159579
RSPRY1
Ring finger and SPRY domain containing 1
[ "Q96DX4" ]
16
57186137-57240469
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA003729" ]
[ "KIAA1972" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[]
[ "Disease variant", "Dwarfism", "Intellectual disability" ]
[]
[]
[ "Secreted to blood" ]
[ "No annotated function" ]
null
Approved
null
8
null
null
Cluster 35: Neutrophils - Protein binding
Cluster 50: Non-specific - Nucleic acid binding
Cluster 68: Non-specific - Cell cycle regulation
Cluster 33: Early spermatids - Spermiogenesis: Cap phase
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
10,197
4
ENSG00000159588
CCDC17
Coiled-coil domain containing 17
[ "Q96LX7" ]
1
45620044-45624057
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028338" ]
[ "FLJ33084" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
3
null
null
null
Cluster 46: Brainstem - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enriched
Detected in some
9
Not detected
Not detected
null
Group enriched
Detected in some
4
Group enriched
Detected in many
9
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,198
1
ENSG00000159592
GPBP1L1
GC-rich promoter binding protein 1 like 1
[ "Q9HC44" ]
1
45627304-45688113
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA028593" ]
[ "SP192" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Plasma membrane", "Focal adhesion sites", "Cytosol" ]
[]
[]
Approved
Approved
null
37
null
null
Cluster 25: Non-specific - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 37: Neutrophil progenitors - Granulopoiesis
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Colon Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,199
7
ENSG00000159593
NAE1
NEDD8 activating enzyme E1 subunit 1
[ "Q13564" ]
16
66802875-66873256
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041178", "HPA042041" ]
[ "APP-BP1", "APPBP1", "ula-1" ]
[ "Essential proteins", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Apoptosis", "Cell cycle", "Ubl conjugation pathway" ]
[]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[ "Microtubules", "Centrosome" ]
[]
[]
Approved
Enhanced
null
26
null
null
Cluster 3: Non-specific - Nuclear processes
Cluster 55: Non-specific - Transcription
Cluster 68: Non-specific - Cell cycle regulation
Cluster 106: Spermatogonia - Spermatogonial differentiation
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,200
7
ENSG00000159596
TMEM69
Transmembrane protein 69
[ "Q5SWH9" ]
1
45688181-45694436
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA026993" ]
[ "C1orf154", "FLJ21029" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Approved
null
14
null
null
Cluster 18: Non-specific - Translation
Cluster 50: Non-specific - Nucleic acid binding
Cluster 37: Non-specific - mRNA processing
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 69: Parathyroid gland - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,201
2
ENSG00000159625
DRC7
Dynein regulatory complex subunit 7
[ "Q8IY82" ]
16
57694793-57731805
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "C16orf50", "CCDC135", "CFAP50", "DKFZp434I099", "FAP50" ]
[ "Predicted intracellular proteins" ]
[ "Differentiation", "Spermatogenesis" ]
[]
[]
[]
[]
[]
[]
null
null
null
4
null
null
null
Cluster 3: Choroid plexus - Cilium
Cluster 10: Ciliated cells - Ion channel activity
Cluster 34: Ciliated cells - Cilia assembly & function
Cluster 56: Ciliated tissues - Cilium organization
Group enriched
Detected in some
11
Cancer enhanced
Detected in some
null
Group enriched
Detected in some
4
Group enriched
Detected in some
6
Immune cell enriched
Detected in some
8
0
0
0
[]
[]
[]
10,203
6
ENSG00000159648
TEPP
Testis, prostate and placenta expressed
[ "Q6URK8" ]
16
57976435-57988116
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA062092" ]
[]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
null
Cluster 30: Non-specific - Gene expression regulation
Cluster 73: Late spermatids - Spermiogenesis: Maturation
Cluster 79: Testis - Spermatogenesis
Tissue enriched
Detected in some
5
Not detected
Not detected
null
Cancer enhanced
Detected in some
null
Group enriched
Detected in many
6
Low immune cell specificity
Detected in single
null
0
0
0
[]
[]
[]
10,205
4
ENSG00000159650
UROC1
Urocanate hydratase 1
[ "Q96N76" ]
3
126481166-126517773
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA069863" ]
[ "FLJ31300", "HMFN0320" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins" ]
[ "Histidine metabolism" ]
[ "Lyase" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
null
null
Cluster 35: RS4;11 - Unknown function
Cluster 25: Hepatocytes - Plasma protein synthesis & secretion
Cluster 53: Liver - Plasma proteins
Tissue enriched
Detected in single
396
Not detected
Not detected
null
Cancer enriched
Detected in single
93
Group enriched
Detected in some
6
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
10,206
1
ENSG00000159658
EFCAB14
EF-hand calcium binding domain 14
[ "O75071" ]
1
46674659-46719146
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA011224", "HPA011938" ]
[ "KIAA0494" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[ "Cytosol" ]
[ "Nucleoli", "Golgi apparatus" ]
[]
[]
Approved
Approved
null
9
null
null
Cluster 1: T-cells - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 69: Urothelial cells - Basic cellular functions
Cluster 69: Parathyroid gland - Mixed function
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
3
2
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Squamous Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
10,207
9
ENSG00000159674
SPON2
Spondin 2
[ "Q9BUD6" ]
4
1166932-1208962
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA040170", "HPA066095" ]
[ "DIL1" ]
[ "Plasma proteins", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[ "Cell adhesion", "Immunity", "Innate immunity" ]
[]
[]
[ "Vesicles" ]
[]
[ "Secreted to blood" ]
[ "Immunity" ]
Approved
Approved
null
3
null
null
Cluster 1: T-cells - Unknown function
Cluster 15: Non-specific - Transcription
Cluster 60: Prostate cancer - Unknown function
Cluster 108: Fibroblasts - ECM organization
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in many
null
Cancer enriched
Detected in many
9
Cancer enriched
Detected in all
5
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
2
0
2
[ "Kidney Renal Papillary Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
10,208
4
ENSG00000159685
CHCHD6
Coiled-coil-helix-coiled-coil-helix domain containing 6
[ "Q9BRQ6" ]
3
126704240-126960420
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA047673", "HPA051975" ]
[ "CHCM1", "MGC13016", "Mic25", "MICOS25", "PPP1R23" ]
[ "Predicted intracellular proteins" ]
[ "Host-virus interaction" ]
[]
[]
[ "Mitochondria" ]
[ "Cytosol" ]
[]
[]
Supported
Approved
null
30
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 29: Forebrain - Mixed function
Cluster 63: Non-specific - Protein processing
Cluster 61: Schwann cells & Melanocytes - Mixed function
Cluster 78: Brain - Neuronal signaling
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,209
9
ENSG00000159692
CTBP1
C-terminal binding protein 1
[ "Q13363" ]
4
1211445-1250333
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB004217", "HPA018987", "HPA044971" ]
[ "BARS" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins" ]
[ "Differentiation", "Host-virus interaction", "Transcription", "Transcription regulation" ]
[ "Oxidoreductase", "Repressor" ]
[ "Disease variant", "Intellectual disability" ]
[ "Nucleoplasm" ]
[]
[]
[]
Enhanced
Approved
null
161
null
null
Cluster 12: Non-specific - Mitochondrial translation
Cluster 32: Cerebral cortex - Mixed function
Cluster 22: Non-specific - mRNA splicing & Cell cycle
Cluster 17: Non-specific - RNA processing
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in all
null
Low immune cell specificity
Detected in all
null
1
0
1
[ "Ovary Serous Cystadenocarcinoma" ]
[]
[ "Ovary Serous Cystadenocarcinoma" ]
10,210
2
ENSG00000159708
LRRC36
Leucine rich repeat containing 36
[ "Q1X8D7" ]
16
67326798-67385204
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA055237", "HPA058479" ]
[ "FLJ11004" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[ "Vesicles" ]
[]
[]
Approved
Enhanced
null
null
null
null
Cluster 44: Plasmacytoid DCs - Plasma membrane proteins
null
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 3: Early primary spermatocytes - Early meiosis
Cluster 43: Placenta - Pregnancy hormone signaling
Tissue enriched
Detected in some
6
Not detected
Not detected
null
Cancer enhanced
Detected in single
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in some
7
0
0
0
[]
[]
[]
10,211
2
ENSG00000159713
TPPP3
Tubulin polymerization promoting protein family member 3
[ "Q9BW30" ]
16
67389809-67393518
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA061691" ]
[ "CGI-38", "p20", "p25gamma" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
1
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 46: Brainstem - Mixed function
Cluster 10: Ciliated cells - Ion channel activity
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 48: Ciliated tissues - Cilium organization
Tissue enhanced
Detected in all
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Glioblastoma Multiforme" ]
[ "Bladder Urothelial Carcinoma", "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
10,212
6
ENSG00000159714
ZDHHC1
Zinc finger DHHC-type containing 1
[ "Q8WTX9" ]
16
67394152-67416833
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042531", "HPA048659" ]
[ "C16orf1", "HSU90653", "ZNF377" ]
[ "Enzymes", "Metabolic proteins", "Predicted membrane proteins" ]
[]
[ "Acyltransferase", "Transferase" ]
[]
[ "Cytosol" ]
[]
[]
[]
Approved
Uncertain
null
14
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 17: Choroid plexus - Cilium
Cluster 27: Breast cancer - Unknown function
Cluster 107: Ciliated cells - Cilia assembly & function
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in some
null
0
0
0
[]
[]
[]
10,213
1
ENSG00000159720
ATP6V0D1
ATPase H+ transporting V0 subunit d1
[ "P61421" ]
16
67438014-67481181
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA016938" ]
[ "ATP6D", "ATP6DV", "P39", "VATX", "Vma6", "VPATPD" ]
[ "Essential proteins", "Metabolic proteins", "Plasma proteins", "Predicted intracellular proteins", "Transporters" ]
[ "Cilium biogenesis/degradation", "Hydrogen ion transport", "Ion transport", "Transport" ]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
72
null
null
Cluster 38: Monocytes & Neutrophils - Degranulation
Cluster 1: Neurons - Mixed function
Cluster 68: Non-specific - Cell cycle regulation
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,214
9
ENSG00000159723
AGRP
Agouti related neuropeptide
[ "O00253" ]
16
67482571-67483547
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA041017", "HPA076241" ]
[ "Agrt", "ART", "ASIP2" ]
[ "Disease related genes", "Human disease related genes", "Plasma proteins", "Predicted secreted proteins" ]
[]
[]
[ "Disease variant", "Obesity" ]
[ "Vesicles" ]
[]
[ "Secreted in brain" ]
[ "No annotated function" ]
Approved
Enhanced
Supported
1
null
null
Cluster 21: Neutrophils - Unknown function
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 35: RS4;11 - Unknown function
Cluster 30: Epididymal principal cells - Sperm storage microenvironment
Cluster 22: Epididymis - Mixed function
Group enriched
Detected in some
9
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in some
null
Cell type enriched
Detected in some
17
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
10,215
4
ENSG00000159733
ZFYVE28
Zinc finger FYVE-type containing 28
[ "Q9HCC9" ]
4
2269582-2418651
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA038175", "HPA057587" ]
[ "KIAA1643", "lst-2" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 39: T-cells - T-cell receptor
Cluster 15: Non-specific - Transcription
Cluster 71: Lymphoma - Inflammatory response
Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis
Cluster 71: Cerebellum - Nervous system development
Tissue enriched
Detected in all
6
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,216
1
ENSG00000159753
CARMIL2
Capping protein regulator and myosin 1 linker 2
[ "Q6F5E8" ]
16
67644988-67657569
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA041402" ]
[ "LRRC16C", "RLTPR" ]
[ "Disease related genes", "Predicted intracellular proteins" ]
[]
[]
[ "Disease variant" ]
[]
[]
[]
[]
null
Approved
null
7
null
null
Cluster 30: Non-specific - DNA binding
Cluster 51: Neurons - Mixed function
Cluster 59: Leukemia - T-cell receptor
Cluster 35: Neurons - Synaptic function & neurogenesis
Cluster 10: Brain - Synaptic signal transduction
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in some
null
3
0
3
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Ovary Serous Cystadenocarcinoma", "Pancreatic Adenocarcinoma" ]
10,217
9
ENSG00000159761
C16orf86
Chromosome 16 open reading frame 86
[ "Q6ZW13" ]
16
67666814-67668757
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA073475" ]
[ "FLJ41802" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Enhanced
null
null
null
null
Cluster 5: Non-specific - Cell proliferation
Cluster 22: Non-specific - Mixed function
Cluster 51: Myeloma - Immunoglobulins
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 67: Testis - Mixed function
Group enriched
Detected in many
5
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
5
Low immune cell specificity
Detected in many
null
3
0
3
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,218
3
ENSG00000159784
FAM131B
Family with sequence similarity 131 member B
[ "Q86XD5" ]
7
143353400-143362770
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA021371", "HPA029992" ]
[ "KIAA0773" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Cytosol" ]
[]
[]
Enhanced
null
null
1
null
null
null
Cluster 53: Neurons - Mixed function
Cluster 17: Neuroblastoma - Neuronal signaling
Cluster 2: Cerebellar granular cells - Neuronal signaling
Cluster 27: Cerebellum - Synaptic function
Tissue enriched
Detected in some
9
Group enriched
Detected in many
4
Cancer enriched
Detected in many
12
Cell type enhanced
Detected in some
null
Not detected in immune cells
Not detected
null
0
0
0
[]
[]
[]
10,220
5
ENSG00000159788
RGS12
Regulator of G protein signaling 12
[ "O14924" ]
4
3293021-3439913
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA054646", "HPA067421" ]
[]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Transcription" ]
[ "GTPase activation", "Repressor", "Signal transduction inhibitor" ]
[]
[ "Nucleoplasm", "Nucleoli" ]
[ "Cytosol" ]
[]
[]
Supported
null
null
9
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 51: Neurons - Mixed function
Cluster 9: Skin cancer - Melanin biosynthesis
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 2: Non-specific - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in some
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma", "Kidney Renal Papillary Cell Carcinoma" ]
10,221
5
ENSG00000159840
ZYX
Zyxin
[ "Q15942" ]
7
143381295-143391111
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA004835", "CAB009321", "HPA073497", "CAB075747" ]
[]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Cell adhesion", "Host-virus interaction" ]
[]
[]
[ "Focal adhesion sites" ]
[ "Plasma membrane", "Actin filaments" ]
[]
[]
Supported
Enhanced
null
56
null
null
Cluster 37: Monocytes & Neutrophils - Innate immune response
Cluster 37: Neurons - Mixed function
Cluster 39: Non-specific - Transcription
Cluster 102: Non-specific - Mixed function
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,223
1
ENSG00000159842
ABR
ABR activator of RhoGEF and GTPase
[ "Q12979" ]
17
1003519-1229738
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA053618", "HPA054824" ]
[ "MDB" ]
[ "Predicted intracellular proteins" ]
[]
[ "GTPase activation", "Guanine-nucleotide releasing factor" ]
[]
[ "Cytosol" ]
[ "Nucleoplasm" ]
[]
[]
Approved
Enhanced
null
3
null
null
Cluster 25: Non-specific - Unknown function
Cluster 51: Neurons - Mixed function
Cluster 46: Lymphoma - Humoral immune response
Cluster 74: Microglia - Neuroimmunity & neuroinflammation
Cluster 68: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Immune cell enriched
Detected in single
14
0
0
0
[]
[]
[]
10,224
1
ENSG00000159871
LYPD5
LY6/PLAUR domain containing 5
[ "Q6UWN5" ]
19
43785874-43827206
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA042511", "HPA054670" ]
[ "FLJ30469" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
8
No
null
Cluster 40: Monocytes - Innate immune response
Cluster 52: Neurons & Synapses - Synaptic function
Cluster 4: Non-specific - Transcription
Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization
Cluster 37: Skin - Keratinization
Tissue enriched
Detected in many
4
Cancer enhanced
Detected in many
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
3
0
3
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
10,225
7
ENSG00000159873
CCDC117
Coiled-coil domain containing 117
[ "Q8IWD4" ]
22
28772674-28789301
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA000826" ]
[ "FLJ33814" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Nucleoplasm" ]
[ "Microtubules", "Cytosol" ]
[]
[]
Approved
Uncertain
null
14
null
null
Cluster 25: Non-specific - Unknown function
Cluster 55: Non-specific - Transcription
Cluster 66: Non-specific - Mitochondria
Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase
Cluster 39: Testis - Nuclear processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Lung Squamous Cell Carcinoma" ]
[ "Thyroid Carcinoma" ]
[ "Lung Squamous Cell Carcinoma", "Thyroid Carcinoma" ]
10,226
5
ENSG00000159882
ZNF230
Zinc finger protein 230
[ "Q9UIE0" ]
19
44002957-44013924
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA006172" ]
[ "FDZF2" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Mitochondria" ]
[]
[]
[]
Approved
null
null
6
No
No
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 16: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 24: Neutrophils - Innate immunity signal integration
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Uterine Corpus Endometrial Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Uterine Corpus Endometrial Carcinoma" ]
10,227
7
ENSG00000159884
CCDC107
Coiled-coil domain containing 107
[ "Q8WV48" ]
9
35658290-35661511
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA016857", "HPA050442" ]
[ "MGC31967" ]
[ "Essential proteins", "Predicted membrane proteins" ]
[]
[]
[]
[ "Plasma membrane", "Cell Junctions" ]
[ "Nucleoplasm" ]
[]
[]
Approved
null
null
30
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 25: Non-specific - Transcription
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 62: Smooth muscle cells - Muscle contraction
Cluster 74: Non-specific - Signal transduction
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Rectum Adenocarcinoma" ]
[ "Rectum Adenocarcinoma" ]
10,228
7
ENSG00000159885
ZNF222
Zinc finger protein 222
[ "Q9UK12" ]
19
44025342-44033110
Evidence at protein level
Evidence at protein level
Evidence at transcript level
Evidence at protein level
[ "HPA004086" ]
[]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nuclear bodies" ]
[]
[]
Approved
Approved
null
null
null
null
Cluster 43: Non-specific - Transcription & Translation
Cluster 25: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 109: Neurons - Neuronal signaling
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in all
null
4
0
4
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Bladder Urothelial Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Pancreatic Adenocarcinoma" ]
10,229
4
ENSG00000159899
NPR2
Natriuretic peptide receptor 2
[ "P20594" ]
9
35791003-35809732
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "AMDM", "ANPb", "ANPRB", "GC-B", "GUCY2B", "NPRB" ]
[ "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins", "Transporters" ]
[ "cGMP biosynthesis", "Osteogenesis" ]
[ "Lyase", "Receptor" ]
[ "Disease variant", "Dwarfism", "FDA approved drug targets" ]
[]
[]
[]
[]
null
null
null
3
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 24: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 108: Fibroblasts - ECM organization
Cluster 12: Smooth muscle tissue - ECM organization
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Papillary Cell Carcinoma" ]
[]
[ "Kidney Renal Papillary Cell Carcinoma" ]
10,230
5
ENSG00000159905
ZNF221
Zinc finger protein 221
[ "Q9UK13" ]
19
43951223-43967709
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA059435" ]
[]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear bodies" ]
[]
[]
[]
Approved
Uncertain
null
3
null
null
Cluster 15: NK-cells - Unknown function
Cluster 16: Non-specific - Transcription
Cluster 4: Non-specific - Transcription
Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in some
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,231
6
ENSG00000159915
ZNF233
Zinc finger protein 233
[ "A6NK53" ]
19
44259880-44275317
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
Evidence at transcript level
[ "HPA020975" ]
[ "FLJ38032" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
null
null
null
Cluster 24: Non-specific - Transcription
Cluster 9: Non-specific - Receptor signaling
Cluster 4: Non-specific - Transcription
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 40: Non-specific - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in many
4
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
10,232
1
ENSG00000159917
ZNF235
Zinc finger protein 235
[ "Q14590" ]
19
44228729-44305046
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA045582" ]
[ "ANF270", "HZF6", "ZFP93", "ZNF270" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[]
[]
[]
Approved
Uncertain
null
3
null
null
Cluster 34: B-cells - Unknown function
Cluster 28: Oligodendrocytes - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 7: Non-specific - Transcription
Cluster 61: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
2
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma" ]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Kidney Renal Clear Cell Carcinoma" ]
10,233
1
ENSG00000159921
GNE
Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
[ "Q9Y223" ]
9
36214441-36277042
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA007045", "HPA027258" ]
[ "IBM2", "Uae1" ]
[ "Disease related genes", "Enzymes", "Human disease related genes", "Metabolic proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Allosteric enzyme", "Hydrolase", "Kinase", "Multifunctional enzyme", "Transferase" ]
[ "Disease variant" ]
[ "Cytosol" ]
[]
[]
[]
Supported
Approved
null
12
null
null
Cluster 33: Non-specific - ATP binding
Cluster 26: Oligodendrocytes - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 70: Intestinal goblet cells - Mucin production
Cluster 45: Liver - Metabolism & Coagulation
Group enriched
Detected in all
4
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in some
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,234
1
ENSG00000159958
TNFRSF13C
TNF receptor superfamily member 13C
[ "Q96RJ3" ]
22
41922032-41926806
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA003246", "CAB008380" ]
[ "BAFFR", "CD268" ]
[ "CD markers", "Disease related genes", "Human disease related genes", "Predicted membrane proteins" ]
[ "Adaptive immunity", "Immunity" ]
[ "Receptor" ]
[ "Disease variant" ]
[]
[]
[]
[]
null
Enhanced
null
2
null
null
Cluster 14: Non-specific - Unknown function
Cluster 43: Hindbrain - Mixed function
Cluster 55: Lymphoma - Immune response
Cluster 87: B-cells - Adaptive immunity: Humoral response
Cluster 18: Lymphoid tissue - Immune response
Group enriched
Detected in some
8
Group enriched
Detected in many
5
Low cancer specificity
Detected in many
null
Group enriched
Detected in some
5
Group enriched
Detected in some
39
2
0
2
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Glioblastoma Multiforme" ]
[]
[ "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma", "Glioblastoma Multiforme" ]
10,235
6
ENSG00000159961
OR3A3
Olfactory receptor family 3 subfamily A member 3
[]
17
3411370-3424070
Evidence at transcript level
Evidence at transcript level
null
null
[]
[ "OR17-137", "OR17-16", "OR17-201", "OR3A6", "OR3A7", "OR3A8P" ]
[ "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
null
null
null
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 37: Neurons - Mixed function
Cluster 21: Lymphoma - Adaptive immune response
Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure
null
Not detected
Not detected
null
Not detected
Not detected
null
Not detected
Not detected
null
Cell type enhanced
Detected in some
null
Immune cell enriched
Detected in single
25
0
0
0
[]
[]
[]
10,236
7
ENSG00000160007
ARHGAP35
Rho GTPase activating protein 35
[ "Q9NRY4" ]
19
46860997-47005077
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "CAB037311", "HPA055184", "HPA056470" ]
[ "GRF-1", "GRLF1", "KIAA1722", "P190A", "p190ARhoGAP", "p190RhoGAP" ]
[ "Cancer-related genes", "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding", "GTPase activation", "Repressor" ]
[ "Cancer-related genes" ]
[ "Nuclear bodies" ]
[ "Microtubules", "Aggresome" ]
[]
[]
Approved
Approved
null
12
null
null
Cluster 30: Non-specific - DNA binding
Cluster 38: Sub-cortical - Mixed function
Cluster 4: Non-specific - Transcription
Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enriched
Detected in many
5
Not detected in immune cells
Not detected
null
1
2
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,237
7
ENSG00000160013
PTGIR
Prostaglandin I2 receptor
[ "P43119" ]
19
46620468-46625089
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "IP" ]
[ "FDA approved drug targets", "G-protein coupled receptors", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "G-protein coupled receptor", "Receptor", "Transducer" ]
[ "FDA approved drug targets" ]
[]
[]
[]
[]
null
null
null
6
null
null
Cluster 40: Monocytes - Innate immune response
Cluster 51: Neurons - Mixed function
Cluster 64: Connective tissue cells - ECM organization
Cluster 47: Platelets - Hemostasis
Cluster 12: Smooth muscle tissue - ECM organization
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Cell type enriched
Detected in some
4
Group enriched
Detected in many
10
1
0
1
[]
[ "Lung Squamous Cell Carcinoma" ]
[ "Lung Squamous Cell Carcinoma" ]
10,238
4
ENSG00000160014
CALM3
Calmodulin 3
[ "P0DP25" ]
19
46601074-46610782
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA044999" ]
[ "PHKD", "PHKD3" ]
[ "Disease related genes", "Human disease related genes", "Metabolic proteins", "Predicted intracellular proteins", "RAS pathway related proteins" ]
[]
[]
[ "Disease variant", "Long QT syndrome" ]
[]
[]
[]
[]
null
Approved
null
205
null
null
Cluster 25: Non-specific - Unknown function
Cluster 14: Neurons - Synaptic function
Cluster 4: Non-specific - Transcription
Cluster 90: Elongating spermatids - Spermiogenesis: Elongation
Cluster 10: Brain - Synaptic signal transduction
Tissue enhanced
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Lung Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Lung Adenocarcinoma" ]
10,239
1
ENSG00000160049
DFFA
DNA fragmentation factor subunit alpha
[ "O00273" ]
1
10456522-10472529
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "CAB002679", "HPA018859", "HPA019938", "HPA025230" ]
[ "DFF-45", "DFF1", "DFF45", "ICAD" ]
[ "Plasma proteins", "Predicted intracellular proteins" ]
[ "Apoptosis" ]
[]
[]
[ "Plasma membrane", "Cytosol" ]
[]
[]
[]
Approved
Supported
null
16
null
null
Cluster 14: Non-specific - Unknown function
Cluster 19: Astrocytes - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 63: Cytotrophoblasts - Basic cellular functions
Cluster 11: Esophagus - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
2
4
0
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,240
1
ENSG00000160050
CCDC28B
Coiled-coil domain containing 28B
[ "Q9BUN5" ]
1
32200595-32205453
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA028589" ]
[ "MGC1203", "RP4-622L5.5" ]
[ "Disease related genes", "Predicted intracellular proteins" ]
[ "Cilium biogenesis/degradation" ]
[]
[ "Bardet-Biedl syndrome", "Ciliopathy", "Obesity" ]
[]
[]
[]
[]
null
Uncertain
null
9
null
null
Cluster 24: Non-specific - Transcription
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 55: Lymphoma - Immune response
Cluster 47: Platelets - Hemostasis
Cluster 19: Skeletal muscle - Striated muscle contraction
Group enriched
Detected in all
5
Cancer enhanced
Detected in all
null
Cancer enhanced
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
3
0
3
[ "Breast Invasive Carcinoma", "Pancreatic Adenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Breast Invasive Carcinoma", "Kidney Renal Clear Cell Carcinoma", "Pancreatic Adenocarcinoma" ]
10,241
6
ENSG00000160051
IQCC
IQ motif containing C
[ "Q4KMZ1" ]
1
32205671-32208682
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA028602", "HPA028686" ]
[ "FLJ10547" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Approved
null
4
null
null
Cluster 24: Non-specific - Transcription
Cluster 48: Non-specific - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 83: Epicardial mesothelial cells - Basic cellular functions
Cluster 21: Testis - Mixed function
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
2
0
2
[ "Testicular Germ Cell Tumor" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma", "Testicular Germ Cell Tumor" ]
10,242
3
ENSG00000160055
TMEM234
Transmembrane protein 234
[ "Q8WY98" ]
1
32214472-32222359
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA015049" ]
[ "C1orf91", "dJ622L5.7", "FLJ90779", "RP4-622L5" ]
[ "Predicted membrane proteins", "Transporters" ]
[]
[]
[]
[ "Vesicles" ]
[]
[]
[]
Approved
Uncertain
null
13
null
null
Cluster 7: Non-specific - Innate immune response
Cluster 17: Choroid plexus - Cilium
Cluster 37: Non-specific - mRNA processing
Cluster 97: Non-specific - Cellular respiration
Cluster 21: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
0
1
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,243
7
ENSG00000160058
BSDC1
BSD domain containing 1
[ "Q9NW68" ]
1
32364633-32394731
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031358", "HPA031360" ]
[ "FLJ10276", "RP4-811H24.7" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Golgi apparatus" ]
[ "Plasma membrane" ]
[]
[]
Supported
Approved
null
3
null
null
Cluster 41: Basophils - Unknown function
Cluster 30: White matter - Myelination
Cluster 37: Non-specific - mRNA processing
Cluster 29: Neutrophils - Innate immune cellular maintenance
Cluster 68: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Immune cell enhanced
Detected in all
null
3
0
3
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[ "Kidney Chromophobe" ]
[ "Glioblastoma Multiforme", "Kidney Chromophobe", "Kidney Renal Clear Cell Carcinoma" ]
10,244
7
ENSG00000160062
ZBTB8A
Zinc finger and BTB domain containing 8A
[ "Q96BR9" ]
1
32539427-32605941
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA031768", "HPA031769", "HPA031770" ]
[ "BOZF1", "FLJ90065", "ZBTB8", "ZNF916A" ]
[ "Predicted intracellular proteins" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nuclear speckles", "Focal adhesion sites" ]
[]
[]
[]
Approved
Approved
null
65
null
null
null
Cluster 48: Non-specific - Mixed function
Cluster 52: Non-specific - Mitochondria
Cluster 94: Gonadal somatic cells - Mixed function
Cluster 75: Ovary - Mixed function
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in single
null
0
0
0
[]
[]
[]
10,245
2
ENSG00000160072
ATAD3B
ATPase family AAA domain containing 3B
[ "Q5T9A4" ]
1
1471765-1497848
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA058968", "HPA064867", "HPA065305" ]
[ "KIAA1273", "TOB3" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[ "Acrosome" ]
[]
[]
Supported
Approved
null
24
null
null
Cluster 10: Non-specific - Membrane trafficking
Cluster 48: Non-specific - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 17: Non-specific - RNA processing
Cluster 64: Non-specific - Transcription
Low tissue specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cancer enhanced
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in single
null
3
0
3
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma", "Ovary Serous Cystadenocarcinoma" ]
10,246
6
ENSG00000160075
SSU72
SSU72 homolog, RNA polymerase II CTD phosphatase
[ "Q9NP77" ]
1
1541673-1574863
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA069290", "HPA070604" ]
[ "HSPC182" ]
[ "Enzymes", "Essential proteins", "Predicted intracellular proteins" ]
[ "mRNA processing" ]
[ "Hydrolase", "Protein phosphatase" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Supported
null
11
No
No
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 1: Neurons - Mixed function
Cluster 37: Non-specific - mRNA processing
Cluster 85: Squamous epithelial cells - Keratinization
Cluster 25: Non-specific - Basic cellular processes
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Kidney Renal Clear Cell Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
[ "Kidney Renal Clear Cell Carcinoma", "Liver Hepatocellular Carcinoma" ]
10,247
5
ENSG00000160087
UBE2J2
Ubiquitin conjugating enzyme E2 J2
[ "Q8N2K1" ]
1
1253909-1273864
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[]
[ "NCUBE2", "Ubc6p" ]
[ "Enzymes", "Metabolic proteins", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "Ubl conjugation pathway", "Unfolded protein response" ]
[ "Transferase" ]
[]
[]
[]
[]
[]
null
null
null
17
null
null
Cluster 36: Eosinophils - Protein ubiquitination
Cluster 25: Non-specific - Transcription
Cluster 37: Non-specific - mRNA processing
Cluster 56: Late spermatids - Spermiogenesis: Maturation
Cluster 67: Testis - Mixed function
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in all
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,248
6
ENSG00000160094
ZNF362
Zinc finger protein 362
[ "Q5T0B9" ]
1
33256492-33300719
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA059239" ]
[ "FLJ25476", "lin-29", "RN" ]
[ "Predicted intracellular proteins", "Transcription factors" ]
[ "Transcription", "Transcription regulation" ]
[ "DNA-binding" ]
[]
[ "Nucleoplasm" ]
[ "Nucleoli" ]
[]
[]
Approved
Uncertain
null
1
null
null
Cluster 8: Plasmacytoid DCs - Unknown function
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 37: Non-specific - mRNA processing
Cluster 7: Non-specific - Transcription
Cluster 24: Non-specific - Transcription
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cell type specificity
Detected in many
null
Low immune cell specificity
Detected in all
null
2
0
2
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Glioblastoma Multiforme", "Kidney Renal Clear Cell Carcinoma" ]
10,249
6
ENSG00000160097
FNDC5
Fibronectin type III domain containing 5
[ "Q8NAU1" ]
1
32862268-32872482
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051290" ]
[ "FRCP2" ]
[ "Predicted membrane proteins" ]
[]
[ "Hormone" ]
[]
[]
[]
[ "Intracellular and membrane" ]
[ "Hormone" ]
null
Enhanced
null
1
null
null
null
Cluster 38: Sub-cortical - Mixed function
Cluster 33: Sarcoma - Muscle contraction
Cluster 109: Neurons - Neuronal signaling
Cluster 62: Skeletal muscle - Muscle contraction
Group enriched
Detected in many
8
Group enriched
Detected in many
5
Group enriched
Detected in many
7
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[ "Liver Hepatocellular Carcinoma" ]
[]
[ "Liver Hepatocellular Carcinoma" ]
10,250
2
ENSG00000160111
CPAMD8
C3 and PZP like alpha-2-macroglobulin domain containing 8
[ "Q8IZJ3" ]
19
16892951-17026815
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA031327", "HPA031328", "HPA031329", "HPA031330" ]
[ "K-CAP", "KIAA1283", "VIP" ]
[ "Disease related genes", "Human disease related genes", "Predicted intracellular proteins", "Predicted secreted proteins" ]
[]
[ "Protease inhibitor", "Serine protease inhibitor" ]
[ "Disease variant" ]
[ "Focal adhesion sites" ]
[]
[ "Secreted to blood" ]
[ "Enzyme inhibitor" ]
Uncertain
Uncertain
null
null
null
null
null
Cluster 39: Astrocytes - Mixed function
Cluster 53: Squamous epithelial cells - Keratinization
Cluster 100: Stratified epithelial cells - Barrier functions
Cluster 22: Epididymis - Mixed function
Tissue enhanced
Detected in many
null
Cancer enhanced
Detected in some
null
Cancer enhanced
Detected in many
null
Cell type enhanced
Detected in many
null
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Pancreatic Adenocarcinoma" ]
[ "Pancreatic Adenocarcinoma" ]
10,251
9
ENSG00000160117
ANKLE1
Ankyrin repeat and LEM domain containing 1
[ "Q8NAG6" ]
19
17281645-17287646
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA026789", "HPA073498" ]
[ "ANKRD41", "FLJ39369", "LEMD6" ]
[ "Predicted intracellular proteins", "Predicted membrane proteins" ]
[ "DNA damage", "DNA repair" ]
[ "Endonuclease", "Hydrolase", "Nuclease" ]
[]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Supported
Approved
null
null
null
null
Cluster 23: B-cells - Immunoglobulins
Cluster 10: Cerebellum - Nucleic acid binding
Cluster 47: Leukemia - Hemostasis
Cluster 66: Erythroid cells - Erythroid differentiation and maturation
Cluster 15: Bone marrow - Innate immune response
Tissue enriched
Detected in some
5
Cancer enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Cell type enhanced
Detected in some
null
Low immune cell specificity
Detected in some
null
0
0
0
[]
[]
[]
10,253
7
ENSG00000160124
MIX23
Mitochondrial matrix import factor 23
[ "Q4VC31" ]
3
122359591-122383231
Evidence at protein level
Evidence at protein level
Evidence at protein level
Evidence at protein level
[ "HPA051965" ]
[ "CCDC58", "FLJ33273" ]
[ "Predicted intracellular proteins" ]
[]
[]
[]
[ "Mitochondria" ]
[ "Nucleoli" ]
[]
[]
Approved
Approved
null
5
No
No
Cluster 30: Non-specific - DNA binding
Cluster 50: Non-specific - Nucleic acid binding
Cluster 63: Non-specific - Protein processing
Cluster 97: Non-specific - Cellular respiration
Cluster 76: Non-specific - Metabolism
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in many
null
5
4
3
[]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
[ "Head and Neck Squamous Cell Carcinoma", "Kidney Chromophobe", "Liver Hepatocellular Carcinoma", "Lung Adenocarcinoma", "Pancreatic Adenocarcinoma" ]
10,254
5
ENSG00000160131
VMA21
Vacuolar ATPase assembly factor VMA21
[ "Q3ZAQ7" ]
X
151396515-151409364
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA010972" ]
[ "MEAX", "XMEA" ]
[ "Disease related genes", "Human disease related genes", "Predicted membrane proteins" ]
[]
[]
[]
[]
[]
[]
[]
null
Uncertain
null
45
null
null
Cluster 11: T-cells - Unknown function
Cluster 41: Monoamines - Neurotransmitter signalling
Cluster 36: Non-specific - mRNA processing
Cluster 40: Monocytes & Neutrophils - Inflammatory signaling
Cluster 1: Choroid plexus - Transmembrane transport
Low tissue specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Low immune cell specificity
Detected in all
null
1
2
0
[]
[ "Liver Hepatocellular Carcinoma" ]
[ "Liver Hepatocellular Carcinoma" ]
10,255
8
ENSG00000160145
KALRN
Kalirin RhoGEF kinase
[ "O60229" ]
3
124033369-124726325
Evidence at protein level
Evidence at transcript level
Evidence at protein level
Evidence at protein level
[ "HPA011913", "CAB026456" ]
[ "ARHGEF24", "DUET", "duo", "HAPIP", "Hs.8004", "Kalirin", "TRAD" ]
[ "Cancer-related genes", "Enzymes", "Human disease related genes", "Predicted intracellular proteins", "Predicted membrane proteins" ]
[]
[ "Guanine-nucleotide releasing factor", "Kinase", "Serine/threonine-protein kinase", "Transferase" ]
[ "Cancer-related genes" ]
[ "Nucleoplasm", "Cytosol" ]
[]
[]
[]
Approved
Approved
null
4
null
null
null
Cluster 40: Astrocytes - Astrocyte-neuron interactions
Cluster 57: Stomach & Colon cancer - Digestion
Cluster 32: Endothelial cells - Angiogenesis & vascular immunity
Cluster 25: Non-specific - Basic cellular processes
Tissue enhanced
Detected in many
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in all
null
Cell type enhanced
Detected in many
null
Immune cell enhanced
Detected in single
null
1
0
1
[ "Kidney Renal Clear Cell Carcinoma" ]
[]
[ "Kidney Renal Clear Cell Carcinoma" ]
10,256
5
ENSG00000160161
CILP2
Cartilage intermediate layer protein 2
[ "Q8IUL8" ]
19
19538248-19546659
Evidence at protein level
Evidence at transcript level
Evidence at transcript level
Evidence at protein level
[ "HPA041847" ]
[ "MGC45771" ]
[ "Predicted secreted proteins" ]
[]
[]
[]
[]
[]
[ "Secreted to extracellular matrix" ]
[ "No annotated function" ]
null
Uncertain
null
15
null
null
null
Cluster 56: Hypothalamus - Neuropeptide signaling
Cluster 4: Non-specific - Transcription
Cluster 53: Late primary spermatocytes - Meiotic division & transition
Cluster 75: Ovary - Mixed function
Tissue enhanced
Detected in some
null
Low cancer specificity
Detected in many
null
Low cancer specificity
Detected in many
null
Group enriched
Detected in some
6
Not detected in immune cells
Not detected
null
1
0
1
[]
[ "Ovary Serous Cystadenocarcinoma" ]
[ "Ovary Serous Cystadenocarcinoma" ]
10,257
2