interpro_id string | interpro_numeric_id int64 | name string | short_name string | entry_type string | protein_count int64 | is_llm bool | is_llm_reviewed bool | abstract string | go_ids list | go_terms list | go_categories list | go_count int64 | member_databases list | member_accessions list | member_names list | member_protein_counts list | member_count int64 | external_databases list | external_accessions list | external_xrefs list | external_xref_count int64 | pdb_ids list | structure_count int64 | publication_ids list | pubmed_ids list | publication_titles list | publication_years list | publication_count int64 | parent_ids list | child_ids list | parent_count int64 | child_count int64 | tree_depth float64 | taxonomy_names list | taxonomy_protein_counts list | taxonomy_count int64 | key_species_names list | key_species_protein_counts list | key_species_count int64 | in_entry_list bool | entry_list_type string | entry_list_name string | names_dat_name string | short_names_dat_name string | split_bucket int64 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
IPR020108 | 20,108 | Spore coat protein CotD | Spore_coat_CotD | Family | 1,036 | false | false | This entry represents spore coat protein D; a capsid protein involved in sporulation. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11122"
] | [
"Spore-coat_CotD"
] | [
1036
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati"
] | [
1036
] | 1 | [] | [] | 0 | true | Family | Spore coat protein CotD | Spore coat protein CotD | Spore_coat_CotD | 7 |
IPR020109 | 20,109 | Holin, r1t-type | Holin_r1t | Family | 1,122 | false | false | Holin is a phage membrane protein that is necessary for host cell lysis. This entry contains holins related to the holin from Lactococcus phage r1t (Bacteriophage r1t) [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF16945"
] | [
"Phage_r1t_holin"
] | [
1122
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00046143"
] | [
"12003945"
] | [
"Expression of Mycobacteriophage Ms6 lysis genes is driven by two sigma(70)-like promoters and is dependent on a transcription termination signal present in the leader RNA."
] | [
2002
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Ecdysozoa",
"Viruses",
"metagenomes"
] | [
689,
2,
423,
8
] | 4 | [] | [] | 0 | true | Family | Holin, r1t-type | Holin, r1t-type | Holin_r1t | 6 |
IPR020112 | 20,112 | Protein of unknown function DUF2883 | DUF2883 | Family | 42 | false | false | This group of proteins currently have no known function and are found primarily in the T4-like bacteriophages. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11097"
] | [
"DUF2883"
] | [
42
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Tevenvirinae"
] | [
42
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF2883 | Protein of unknown function DUF2883 | DUF2883 | 6 |
IPR020113 | 20,113 | Protein of unknown function DUF5439 | DUF5439 | Family | 14 | false | false | This is a family of unknown function found in Orthopoxvirus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17507"
] | [
"DUF5439"
] | [
14
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Orthopoxvirus"
] | [
14
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5439 | Protein of unknown function DUF5439 | DUF5439 | 5 |
IPR020115 | 20,115 | Anti-sigma-F factor Fin | Fin | Family | 1,351 | false | false | Fin (formerly known as YabK) is a small protein required for efficient switching from sigma(F)- to sigma(G)-directed gene expression during sporulation in Bacillus subtilis. Fin has been proposed to be an anti-sigma(F) factor which, by disabling sigma(F), promotes the switch to late developmental gene expression in the... | [
"GO:0010468"
] | [
"regulation of gene expression"
] | [
"biological_process"
] | 1 | [
"PFAM"
] | [
"PF10955"
] | [
"Fin"
] | [
1351
] | 1 | [] | [] | [] | 0 | [
"5msl"
] | 1 | [
"PUB00078865"
] | [
"21037003"
] | [
"A small protein required for the switch from {sigma}F to {sigma}G during sporulation in Bacillus subtilis."
] | [
2011
] | 1 | [] | [] | 0 | 0 | null | [
"Bacillota",
"bioreactor metagenome"
] | [
1348,
3
] | 2 | [] | [] | 0 | true | Family | Anti-sigma-F factor Fin | Anti-sigma-F factor Fin | Fin | 4 |
IPR020117 | 20,117 | Uncharacterised protein family YncJ | Uncharacterised_YncJ | Family | 648 | false | false | This entry contains proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10829"
] | [
"DUF2554"
] | [
648
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
648
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family YncJ | Uncharacterised protein family YncJ | Uncharacterised_YncJ | 5 |
IPR020119 | 20,119 | Pseudouridine synthase TruD, conserved site | PsdUridine_synth_TruD_CS | Conserved_site | 9,348 | false | false | Pseudouridine synthases catalyse the isomerisation of uridine to pseudouridine (Psi) in a variety of RNA molecules, and may function as RNA chaperones. Pseudouridine is the most abundant modified nucleotide found in all cellular RNAs. There are four distinct families of pseudouridine synthases that share no global sequ... | [
"GO:0003723",
"GO:0009982",
"GO:0001522",
"GO:0009451"
] | [
"RNA binding",
"pseudouridine synthase activity",
"pseudouridine synthesis",
"RNA modification"
] | [
"molecular_function",
"molecular_function",
"biological_process",
"biological_process"
] | 4 | [
"PROSITE"
] | [
"PS01268"
] | [
"UPF0024"
] | [
9348
] | 1 | [
"EC",
"REACTOME"
] | [
"5.4.99.27",
"R-HSA-6782315"
] | [
"EC:5.4.99.27",
"REACTOME:R-HSA-6782315"
] | 2 | [
"1sb7",
"1si7",
"1szw",
"1z2z",
"5kkp",
"7mzv"
] | 6 | [
"PUB00014308",
"PUB00015731",
"PUB00015813",
"PUB00045922",
"PUB00092579"
] | [
"12756329",
"15135053",
"15208439",
"10529181",
"19664587"
] | [
"A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya.",
"X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold.",
"Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a... | [
2003,
2004,
2004,
1999,
2009
] | 5 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Eukaryota",
"unclassified sequences"
] | [
755,
5400,
3129,
64
] | 4 | [
"Caenorhabditis elegans",
"Danio rerio",
"Escherichia coli (strain K12)",
"Homo sapiens",
"Mus musculus",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)",
"Schizosaccharomyces pombe (strain 972 / ATCC 24843)",
"Zea mays"
] | [
1,
7,
1,
4,
3,
8,
4,
1,
1,
19
] | 10 | true | Conserved_site | Pseudouridine synthase TruD, conserved site | Pseudouridine synthase TruD, conserved site | PsdUridine_synth_TruD_CS | 6 |
IPR020120 | 20,120 | Plasmid pGKL2, Orf8 | Plasmid_pGKL2_Orf8 | Family | 5 | false | false | The proteins in this entry represent Orf8 from killer plasmid K2 (pGKL2) of Kluyveromyces lactis (Yeast) (Candida sphaerica). K2 contains ten open reading frames. Some of the ORFs overlap on different strands and some on the same strand and at least 8 of the 10 ORFs are transcribed. Comparison of the sequence of pGKL2 ... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17568"
] | [
"DUF5474"
] | [
5
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045923"
] | [
"3041369"
] | [
"Genome organization of the killer plasmid pGK12 from Kluyveromyces lactis."
] | [
1988
] | 1 | [] | [] | 0 | 0 | null | [
"Saccharomycotina"
] | [
5
] | 1 | [] | [] | 0 | true | Family | Plasmid pGKL2, Orf8 | Plasmid pGKL2, Orf8 | Plasmid_pGKL2_Orf8 | 4 |
IPR020121 | 20,121 | Bacteriophage T7-like gene 6.5 | Phage_T7-like_6.5 | Family | 441 | false | false | The proteins in this entry are uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10911"
] | [
"T7-like_Y65"
] | [
441
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses"
] | [
8,
433
] | 2 | [] | [] | 0 | true | Family | Bacteriophage T7-like gene 6.5 | Bacteriophage T7-like gene 6.5 | Phage_T7-like_6.5 | 2 |
IPR020122 | 20,122 | Alphabaculovirus, Y056 | Alphabaculovirus_Y056 | Family | 49 | false | false | This protein family contains uncharacterised proteins mainly found in Alphabaculovirus, including Uncharacterized 9.7 kDa protein from Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) and Uncharacterized 9.9 kDa protein in LEF8-FP intergenic region from Autographa californica nuclear polyhedrosis virus (AcM... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10891"
] | [
"DUF2719"
] | [
49
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphabaculovirus"
] | [
49
] | 1 | [] | [] | 0 | true | Family | Alphabaculovirus, Y056 | Alphabaculovirus, Y056 | Alphabaculovirus_Y056 | 1 |
IPR020123 | 20,123 | Protein of unknown function DUF5475 | DUF5475 | Family | 36 | false | false | This is a family of unknown function found in Alphabaculovirus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17569"
] | [
"DUF5475"
] | [
36
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphabaculovirus"
] | [
36
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5475 | Protein of unknown function DUF5475 | DUF5475 | 8 |
IPR020125 | 20,125 | Protein of unknown function DUF5488 | DUF5488 | Family | 30 | false | false | This is a family of unknown function found in Orthopoxvirus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17590"
] | [
"DUF5488"
] | [
30
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Orthopoxvirus"
] | [
30
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5488 | Protein of unknown function DUF5488 | DUF5488 | 7 |
IPR020126 | 20,126 | Protein of unknown function DUF2732 | DUF2732 | Family | 1,542 | false | false | This entry represents a group of proteins with no known function | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10809"
] | [
"DUF2732"
] | [
1542
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Caudoviricetes",
"Pseudomonadota",
"metagenomes"
] | [
69,
1470,
3
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2732 | Protein of unknown function DUF2732 | DUF2732 | 7 |
IPR020127 | 20,127 | Colicin-E5 immunity protein | Colicin-E5_imm | Family | 83 | false | false | Colicins, which are produced by bacteria carrying the corresponding Col plasmids, kill sensitive Escherichia coli cells using different mechanisms. Colicin E5 is a tRNase toxin. The immunity protein ImmE5 is a specific inhibitor of colicin E5 that is expressed to protect the host cells. It binds to E5 C-terminal ribonu... | [
"GO:0030153"
] | [
"bacteriocin immunity"
] | [
"biological_process"
] | 1 | [
"PFAM"
] | [
"PF11480"
] | [
"ImmE5"
] | [
83
] | 1 | [] | [] | [] | 0 | [
"2dfx",
"2fhz"
] | 2 | [
"PUB00040245",
"PUB00040676"
] | [
"17099236",
"16524591"
] | [
"Structural basis for sequence-dependent recognition of colicin E5 tRNase by mimicking the mRNA-tRNA interaction.",
"Molecular basis of inhibition of the ribonuclease activity in colicin E5 by its cognate immunity protein."
] | [
2006,
2006
] | 2 | [] | [] | 0 | 0 | null | [
"Pseudomonadati"
] | [
83
] | 1 | [] | [] | 0 | true | Family | Colicin-E5 immunity protein | Colicin-E5 immunity protein | Colicin-E5_imm | 6 |
IPR020128 | 20,128 | Secapin | Secapin | Family | 21 | false | false | This entry represents Secapin; a nontoxic peptide found in the venom of bees and wasps, a serine protease inhibitor which exhibits antifibrinolytic, antielastolytic and antimicrobial activities against bacteria and fungi [ ]. It may function in the innate immune response to microbial infection and possibly in the venom... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17521"
] | [
"Secapin"
] | [
21
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045928",
"PUB00097952",
"PUB00097953"
] | [
"7213796",
"27208884",
"25017240"
] | [
"A comparative structural study of apamin and related bee venom peptides.",
"Secapin, a bee venom peptide, exhibits anti-fibrinolytic, anti-elastolytic, and anti-microbial activities.",
"Hyperalgesic and edematogenic effects of Secapin-2, a peptide isolated from Africanized honeybee (Apis mellifera) venom."
] | [
1981,
2016,
2014
] | 3 | [] | [] | 0 | 0 | null | [
"Endopterygota"
] | [
21
] | 1 | [] | [] | 0 | true | Family | Secapin | Secapin | Secapin | 3 |
IPR020130 | 20,130 | Spanin, outer lipoprotein subunit, T7likevirus | O-spanin_T7likevirus | Family | 96 | false | false | The lysis of Gram-negative hosts by double-strand DNA bacteriophages requires, in addition to the actions of a holin and endolysin, a third step involving the spanin complex. This complex consists of a small outer membrane lipoprotein and an integral cytoplasmic membrane protein, designated as o-spanins and i-spanins, ... | [
"GO:0019076"
] | [
"viral release from host cell"
] | [
"biological_process"
] | 1 | [
"PFAM"
] | [
"PF17531"
] | [
"O_Spanin_T7"
] | [
96
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00082268"
] | [
"24585055"
] | [
"Phage lysis: three steps, three choices, one outcome."
] | [
2014
] | 1 | [] | [] | 0 | 0 | null | [
"Pseudomonas fildesensis",
"Studiervirinae"
] | [
1,
95
] | 2 | [] | [] | 0 | true | Family | Spanin, outer lipoprotein subunit, T7likevirus | Spanin, outer lipoprotein subunit, T7likevirus | O-spanin_T7likevirus | 1 |
IPR020132 | 20,132 | Mycobacteriophage tail assembly protein 24/25 | Gp24/Gp25 | Family | 774 | false | false | This entry includes the tail assembly protein Gp24 and Gp25. In some strains Gp24 is the N-terminal domain of a fusion protein with the following ORF, Gp25. In Mycobacteriophages these proteins are likely to interact with the tape measure protein [ , ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17388"
] | [
"GP24_25"
] | [
774
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00098615",
"PUB00098616"
] | [
"26713219",
"30291704"
] | [
"Mycobacteriophage cell binding proteins for the capture of mycobacteria.",
"Mycobacteriophages."
] | [
2014,
2018
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses"
] | [
71,
703
] | 2 | [] | [] | 0 | true | Family | Mycobacteriophage tail assembly protein 24/25 | Mycobacteriophage tail assembly protein 24/25 | Gp24/Gp25 | 2 |
IPR020133 | 20,133 | Decidual protein, progesterone induced | DEPP | Family | 452 | false | false | This entry represents proteins from various mammals known as DEPP proteins, which are decidual proteins induced by progesterone. Decidualization of the endometrial stromal cells (ESC) is thought to be stimulated by progesterone and/or cAMP and is crucial for embryo implantation and placentation. Increased expression of... | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF15343",
"PTHR15426"
] | [
"DEPP",
""
] | [
260,
442
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045931"
] | [
"16123073"
] | [
"A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor."
] | [
2005
] | 1 | [] | [] | 0 | 0 | null | [
"Gnathostomata"
] | [
452
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
3,
2,
3
] | 4 | true | Family | Decidual protein, progesterone induced | Decidual protein, progesterone induced | DEPP | 9 |
IPR020134 | 20,134 | Bacteriophage T7-like, protein 6.7 | Phage_T7-like_6.7 | Family | 411 | false | false | Protein 6.7 is ejected from the infecting virion. It is found in tail-less particles and has been defined as a head protein [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17570"
] | [
"T7-like_gp67"
] | [
411
] | 1 | [] | [] | [] | 0 | [
"9jyy",
"9jyz",
"9jz0",
"9vvp"
] | 4 | [
"PUB00055981"
] | [
"16054667"
] | [
"Changes in bacteriophage T7 virion structure at the initiation of infection."
] | [
2005
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Viruses"
] | [
7,
404
] | 2 | [] | [] | 0 | true | Family | Bacteriophage T7-like, protein 6.7 | Bacteriophage T7-like, protein 6.7 | Phage_T7-like_6.7 | 2 |
IPR020135 | 20,135 | Uncharacterised protein family RP854 | Uncharacterised_RP854 | Family | 47 | false | false | This entry represents proteins related to RP854 from Rickettsia prowazekii. They are currently uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17460"
] | [
"RP854"
] | [
47
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Oppiella nova",
"Rickettsiaceae"
] | [
1,
46
] | 2 | [] | [] | 0 | true | Family | Uncharacterised protein family RP854 | Uncharacterised protein family RP854 | Uncharacterised_RP854 | 4 |
IPR020138 | 20,138 | Uncharacterised protein family YqzF | Uncharacterised_YqzF | Family | 1,404 | false | false | This entry represents uncharacterised membrane proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11118"
] | [
"DUF2627"
] | [
1404
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
1404
] | 1 | [] | [] | 0 | true | Family | Uncharacterised protein family YqzF | Uncharacterised protein family YqzF | Uncharacterised_YqzF | 3 |
IPR020139 | 20,139 | Protein of unknown function DUF2642 | DUF2642 | Family | 910 | false | false | This entry contains proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10842"
] | [
"DUF2642"
] | [
910
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati"
] | [
910
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF2642 | Protein of unknown function DUF2642 | DUF2642 | 6 |
IPR020141 | 20,141 | Herpesvirus UL41A | Herpesvirus_UL41A | Family | 19 | false | false | This entry represents proteins from Herpesvirus. The protein UL41A is thought to be a membrane associated glycoprotein but is currently uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17591"
] | [
"UL41A"
] | [
19
] | 1 | [
"REACTOME"
] | [
"R-HSA-9610379"
] | [
"REACTOME:R-HSA-9610379"
] | 1 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Cytomegalovirus"
] | [
19
] | 1 | [] | [] | 0 | true | Family | Herpesvirus UL41A | Herpesvirus UL41A | Herpesvirus_UL41A | 6 |
IPR020142 | 20,142 | Protein of unknown function DUF5489 | DUF5489 | Family | 15 | false | false | This is a family of unknown function found in Alphafusellovirus including Uncharacterized protein B-78. This entry includes some uncharacterised archaeal proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17592"
] | [
"DUF5489"
] | [
15
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphafusellovirus",
"Sulfolobaceae"
] | [
7,
8
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF5489 | Protein of unknown function DUF5489 | DUF5489 | 1 |
IPR020144 | 20,144 | Stage V sporulation protein AB | SpoVAB | Family | 1,642 | false | false | This entry represents stage V sporulation protein AB (SpoVAB), which is involved in spore germination and is located in the spores' inner membrane. In Bacillus subtilis, SpoVA proteins are a component of a dipicolinic acid (DPA) channel in the spore's inner membrane and are involved in DPA release [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF13782"
] | [
"SpoVAB"
] | [
1642
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045929"
] | [
"17718850"
] | [
"Studies of the release of small molecules during pressure germination of spores of Bacillus subtilis."
] | [
2007
] | 1 | [] | [] | 0 | 0 | null | [
"Bacillati",
"metagenomes"
] | [
1639,
3
] | 2 | [] | [] | 0 | true | Family | Stage V sporulation protein AB | Stage V sporulation protein AB | SpoVAB | 1 |
IPR020147 | 20,147 | Inhibitor of dGTPase, bacteriophage T7-like | Phage_T7-like_1.2 | Family | 174 | false | false | The T7-like bacteriophage gene 1.2 protein is an inhibitor of the Escherichia coli dGTP triphosphohydrolase (dGTPase) and is implicated in DNA replication. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10922"
] | [
"T7-like_gp12"
] | [
174
] | 1 | [] | [] | [] | 0 | [
"2mdp",
"7u65",
"7u66",
"7u67"
] | 4 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Caudoviricetes",
"Eumeta variegata"
] | [
173,
1
] | 2 | [] | [] | 0 | true | Family | Inhibitor of dGTPase, bacteriophage T7-like | Inhibitor of dGTPase, bacteriophage T7-like | Phage_T7-like_1.2 | 7 |
IPR020148 | 20,148 | Protein of unknown function DUF5477 | DUF5477 | Family | 14 | false | false | This is a family of proteins of unknown function found in phages. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17571"
] | [
"DUF5477"
] | [
14
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Studiervirinae"
] | [
14
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5477 | Protein of unknown function DUF5477 | DUF5477 | 3 |
IPR020149 | 20,149 | Uncharacterised protein family C02F5.10 | Uncharacterised_C02F5.10 | Family | 119 | false | false | The proteins in this entry are uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17309"
] | [
"DUF5356"
] | [
119
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Rhabditida"
] | [
119
] | 1 | [
"Caenorhabditis elegans"
] | [
2
] | 1 | true | Family | Uncharacterised protein family C02F5.10 | Uncharacterised protein family C02F5.10 | Uncharacterised_C02F5.10 | 9 |
IPR020150 | 20,150 | Type IV conjugative transfer system protein TrbE | T4SS_TrbE | Family | 445 | false | false | TrbE is encoded by the F-plasmid and is located between traN and traF. The product of trbE is a small, integral, inner membrane protein. Mutation of trbE by insertional mutagenesis suggests that TrbE is not essential for F transfer from Escherichia coli (strain K12) under standard mating conditions [ ]. | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM"
] | [
"NF010271",
"PF11100"
] | [
"PRK13718.1",
"TrbE"
] | [
394,
445
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00020464"
] | [
"1593622"
] | [
"Characterization of the F plasmid mating aggregation gene traN and of a new F transfer region locus trbE."
] | [
1992
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
445
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Type IV conjugative transfer system protein TrbE | Type IV conjugative transfer system protein TrbE | T4SS_TrbE | 7 |
IPR020151 | 20,151 | Protein of unknown function DUF5478 | DUF5478 | Family | 44 | false | false | This is a family of unknown function found in Alphabaculovirus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17572"
] | [
"DUF5478"
] | [
44
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphabaculovirus"
] | [
44
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5478 | Protein of unknown function DUF5478 | DUF5478 | 7 |
IPR020155 | 20,155 | Uncharacterised protein family YeiS | Uncharacterised_YeiS | Family | 700 | false | false | This entry represents transmembrane proteins with no known function. | [
"GO:0016020"
] | [
"membrane"
] | [
"cellular_component"
] | 1 | [
"PFAM"
] | [
"PF10808"
] | [
"DUF2542"
] | [
700
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadota"
] | [
700
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family YeiS | Uncharacterised protein family YeiS | Uncharacterised_YeiS | 7 |
IPR020156 | 20,156 | Protein of unknown function DUF5490 | DUF5490 | Family | 171 | false | false | This is a family of unknown function found mainly in Straboviridae. This entry includes Uncharacterized 9.2 kDa protein in Gp55-nrdG intergenic region. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17593"
] | [
"DUF5490"
] | [
171
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Viruses"
] | [
171
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5490 | Protein of unknown function DUF5490 | DUF5490 | 7 |
IPR020157 | 20,157 | Uncharacterised protein family YqkC | Uncharacterised_YqkC | Family | 272 | false | false | This entry contains proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10827"
] | [
"DUF2552"
] | [
272
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
272
] | 1 | [] | [] | 0 | true | Family | Uncharacterised protein family YqkC | Uncharacterised protein family YqkC | Uncharacterised_YqkC | 5 |
IPR020158 | 20,158 | Protein of unknown function DUF2756 | DUF2756 | Family | 1,030 | false | false | This entry contains proteins with no known function. | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM"
] | [
"NF007675",
"PF10956"
] | [
"PRK10350.1",
"DUF2756"
] | [
868,
1030
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Seminavis robusta",
"human gut metagenome"
] | [
1028,
1,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Protein of unknown function DUF2756 | Protein of unknown function DUF2756 | DUF2756 | 8 |
IPR020159 | 20,159 | Tail fiber assembly helper protein | Gp57 | Family | 195 | false | false | Tail fiber assembly helper protein (Gp57) is a chaperone protein for short tail fibre phage protein, that acts as a molecular chaperone of gp12, increasing the folding efficacy and production efficiency [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17594"
] | [
"GP57"
] | [
195
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00085214"
] | [
"27471503"
] | [
"T4 Phage Tail Adhesin Gp12 Counteracts LPS-Induced Inflammation In Vivo."
] | [
2016
] | 1 | [] | [] | 0 | 0 | null | [
"Viruses"
] | [
195
] | 1 | [] | [] | 0 | true | Family | Tail fiber assembly helper protein | Tail fiber assembly helper protein | Gp57 | 5 |
IPR020162 | 20,162 | Cell cycle exit/neuronal differentiation protein 1 | Cend1 | Family | 618 | false | false | Cell cycle exit and neuronal differentiation protein 1 (Cend1 or BM88) is a homodimer of 140 amino acids. It has a putative transmembrane domain at the C terminus. The mRNA of this protein is expressed only in neural tissues, where it is restricted to neurons. It is involved in neuroblastoma cell differentiation [ , ],... | [
"GO:0021549",
"GO:0030182"
] | [
"cerebellum development",
"neuron differentiation"
] | [
"biological_process",
"biological_process"
] | 2 | [
"PFAM",
"PANTHER"
] | [
"PF15677",
"PTHR36683"
] | [
"CEND1",
""
] | [
618,
564
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045934",
"PUB00075747",
"PUB00075748",
"PUB00075749"
] | [
"7775480",
"20153830",
"23658157",
"24312406"
] | [
"The BM88 antigen, a novel neuron-specific molecule, enhances the differentiation of mouse neuroblastoma cells.",
"Impaired cerebellar development and deficits in motor coordination in mice lacking the neuronal protein BM88/Cend1.",
"Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuron... | [
1995,
2010,
2013,
2013
] | 4 | [] | [] | 0 | 0 | null | [
"Gnathostomata"
] | [
618
] | 1 | [
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
2,
1,
2
] | 3 | true | Family | Cell cycle exit/neuronal differentiation protein 1 | Cell cycle exit/neuronal differentiation protein 1 | Cend1 | 4 |
IPR020164 | 20,164 | Cytochrome c oxidase assembly protein COX16 | Cyt_c_Oxase_assmbl_COX16 | Family | 3,473 | false | false | Cytochrome c oxidase assembly protein COX16 is required for the assembly of cytochrome c oxidase [ ]. It is found in the inner membrane of the mitochondrion. | [
"GO:0031966"
] | [
"mitochondrial membrane"
] | [
"cellular_component"
] | 1 | [
"PFAM"
] | [
"PF14138"
] | [
"COX16"
] | [
3473
] | 1 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-BTA-9864848",
"R-CEL-9864848",
"R-HSA-9864848",
"R-MMU-9864848"
] | [
"REACTOME:R-BTA-9864848",
"REACTOME:R-CEL-9864848",
"REACTOME:R-HSA-9864848",
"REACTOME:R-MMU-9864848"
] | 4 | [] | 0 | [
"PUB00057336"
] | [
"12446688"
] | [
"COX16 encodes a novel protein required for the assembly of cytochrome oxidase in Saccharomyces cerevisiae."
] | [
2003
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
3473
] | 1 | [
"Arabidopsis thaliana",
"Caenorhabditis elegans",
"Danio rerio",
"Drosophila melanogaster",
"Homo sapiens",
"Mus musculus",
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Oryza sativa subsp. japonica",
"Rattus norvegicus",
"Saccharomyces cerevisiae (strai... | [
2,
2,
1,
3,
4,
8,
1,
3,
3,
1,
1,
3
] | 12 | true | Family | Cytochrome c oxidase assembly protein COX16 | Cytochrome c oxidase assembly protein COX16 | Cyt_c_Oxase_assmbl_COX16 | 7 |
IPR020168 | 20,168 | Uncharacterised protein family RP363/RP364 | Uncharacterised_RP363/RP364 | Family | 86 | false | false | This entry represents proteins that are confined to Rickettsiales. The proteins include RP363 and RP364, which are currently uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17422"
] | [
"DUF5410"
] | [
86
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudolycoriella hygida",
"Rickettsia"
] | [
1,
85
] | 2 | [] | [] | 0 | true | Family | Uncharacterised protein family RP363/RP364 | Uncharacterised protein family RP363/RP364 | Uncharacterised_RP363/RP364 | 4 |
IPR020169 | 20,169 | Intrinsic membrane protein family, PufX | Intrinsic_membrane_PufX | Family | 95 | false | false | PufX organises RC-LH1, the photosynthesis reaction centre-light harvesting complex 1 core complex of Rhodobacter sphaeroides [ ]. It also facilitates the exchange of quinol for quinone between the reaction centre and cytochrome bc(1) complexes. In organic solvent, PufX contains two hydrophobic helices which are flanked... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11511"
] | [
"RhodobacterPufX"
] | [
95
] | 1 | [] | [] | [] | 0 | [
"2dw3",
"2ita",
"2nrg",
"4v9g",
"7ddq",
"7f0l",
"7pil",
"7pqd",
"7va9",
"7vb9",
"7vnm",
"7vny",
"7vor",
"7vot",
"7vy2",
"7vy3",
"7yml",
"8b64",
"8ygd",
"8ygl"
] | 20 | [
"PUB00041775"
] | [
"17161397"
] | [
"The solution structure of the PufX polypeptide from Rhodobacter sphaeroides."
] | [
2006
] | 1 | [] | [] | 0 | 0 | null | [
"Pseudomonadota"
] | [
95
] | 1 | [] | [] | 0 | true | Family | Intrinsic membrane protein family, PufX | Intrinsic membrane protein family, PufX | Intrinsic_membrane_PufX | 6 |
IPR020170 | 20,170 | Herpesvirus UL11, muromegalovirus/roseolovirus-type | Herpes_UL11_megaloV/roseoloV | Family | 39 | false | false | UL11 (also known as cytoplasmic envelopment protein 3) is conserved throughout the herpesvirus family. It is a membrane-associated tegument protein that is incorporated into the HSV virion. UL11 and UL51, either singly or in combination, are involved in virion envelopment and/or egress. Both proteins are fatty acylated... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17474"
] | [
"U71"
] | [
39
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045941",
"PUB00085328"
] | [
"17694428",
"23152545"
] | [
"Herpes simplex virus protein UL11 but not UL51 is associated with lipid rafts.",
"Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation."
] | [
2007,
2013
] | 2 | [
"IPR034705"
] | [] | 1 | 0 | 1 | [
"Betaherpesvirinae",
"Homo sapiens"
] | [
38,
1
] | 2 | [
"Homo sapiens"
] | [
1
] | 1 | true | Family | Herpesvirus UL11, muromegalovirus/roseolovirus-type | Herpesvirus UL11, muromegalovirus/roseolovirus-type | Herpes_UL11_megaloV/roseoloV | 8 |
IPR020171 | 20,171 | Uncharacterised protein family RC0039 | Uncharacterised_RC0039 | Family | 62 | false | false | This entry represents proteins that are confined to Rickettsiales. The proteins, which include RC0039 and RP030, are currently uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17372"
] | [
"DUF5394"
] | [
62
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Arthropoda",
"Rickettsiales"
] | [
2,
60
] | 2 | [] | [] | 0 | true | Family | Uncharacterised protein family RC0039 | Uncharacterised protein family RC0039 | Uncharacterised_RC0039 | 5 |
IPR020180 | 20,180 | Uncharacterised protein family RP853 | Uncharacterised_RP853 | Family | 48 | false | false | This entry represents proteins that are confined to Rickettsia. The family member RP853 is thought to be a transmembrane protein, but is currently uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17542"
] | [
"RP853"
] | [
48
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Oppiella nova",
"Rickettsiaceae"
] | [
1,
47
] | 2 | [] | [] | 0 | true | Family | Uncharacterised protein family RP853 | Uncharacterised protein family RP853 | Uncharacterised_RP853 | 6 |
IPR020181 | 20,181 | Ant venom allergen, Sol i 2 | Ant_venom_allergen_Sol_i_2 | Family | 11 | false | false | Fire ant venom from Solenopsis invicta (Red imported fire ant), is an extremely potent allergy-inducing agent containing four major allergens, Sol i 1 to Sol i 4 [ , ]. This family contains the allergens Sol i 2. Sol i 2 causes IgE antibody production in about one-third of individuals stung by fire ants. This allergen ... | [] | [] | [] | 0 | [
"CDD"
] | [
"cd12800"
] | [
"Sol_i_2"
] | [
11
] | 1 | [] | [] | [] | 0 | [
"2ygu"
] | 1 | [
"PUB00057651",
"PUB00080438",
"PUB00080439"
] | [
"22100449",
"3192865",
"8423273"
] | [
"Crystal structure of sol I 2: a major allergen from fire ant venom.",
"Allergens in Hymenoptera venom. XX. Isolation of four allergens from imported fire ant (Solenopsis invicta) venom.",
"Allergens in Hymenoptera venom XXIV: the amino acid sequences of imported fire ant venom allergens Sol i II, Sol i III, an... | [
2012,
1988,
1993
] | 3 | [] | [] | 0 | 0 | null | [
"Solenopsis"
] | [
11
] | 1 | [] | [] | 0 | true | Family | Ant venom allergen, Sol i 2 | Ant venom allergen, Sol i 2 | Ant_venom_allergen_Sol_i_2 | 8 |
IPR020182 | 20,182 | Protein of unknown function DUF5460 | DUF5460 | Family | 44 | false | false | This is a family of unknown function found in Rickettsia. Family members are predicted to contain one trans-membrane region. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17544"
] | [
"DUF5460"
] | [
44
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bemisia tabaci",
"Rickettsia"
] | [
1,
43
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF5460 | Protein of unknown function DUF5460 | DUF5460 | 9 |
IPR020183 | 20,183 | Uncharacterised protein family RC0048 | Uncharacterised_RC0048 | Family | 62 | false | false | This entry represents proteins that are mainly confined to Rickettsia and Orientia. The proteins, which include RP364 and RC0048, are currently uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10871"
] | [
"DUF2748"
] | [
62
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Rickettsiales"
] | [
2,
60
] | 2 | [] | [] | 0 | true | Family | Uncharacterised protein family RC0048 | Uncharacterised protein family RC0048 | Uncharacterised_RC0048 | 9 |
IPR020184 | 20,184 | Keratin-associated protein 7 | KRTAP7 | Family | 135 | false | false | This family includes keratin-associated protein 7-1, a member of the type 7 family. In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft throug... | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF15034",
"PTHR38504"
] | [
"KRTAP7",
""
] | [
135,
135
] | 2 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Mammalia"
] | [
135
] | 1 | [
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
1
] | 3 | true | Family | Keratin-associated protein 7 | Keratin-associated protein 7 | KRTAP7 | 8 |
IPR020185 | 20,185 | Spore morphogenesis/germination protein YwcE | Spore_morphogenesis_YwcE | Family | 158 | false | false | Spore morphogenesis and germination protein YwcE is required for proper spore morphogenesis and germination. It is repressed by abrB during growth and activated at the onset of sporulation in a spo0A-dependent manner. This protein has similar features to holin [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17368"
] | [
"YwcE"
] | [
158
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045951"
] | [
"16159778"
] | [
"A gene encoding a holin-like protein involved in spore morphogenesis and spore germination in Bacillus subtilis."
] | [
2005
] | 1 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
158
] | 1 | [] | [] | 0 | true | Family | Spore morphogenesis/germination protein YwcE | Spore morphogenesis/germination protein YwcE | Spore_morphogenesis_YwcE | 5 |
IPR020186 | 20,186 | Meiosis-expressed gene 1 protein | Meiosis-expressed_gene_1 | Family | 976 | false | false | This entry represents Meiosis-expressed gene 1 protein and its homologues, encoded by the gene MEIG1. It may be involved in germ cell differentiation during meiotic prophase. Sequence analysis predicts this protein to be 10.8kDa in size and to be highly charged and lysine rich [ ]. | [
"GO:0005634"
] | [
"nucleus"
] | [
"cellular_component"
] | 1 | [
"PFAM",
"PANTHER"
] | [
"PF15163",
"PTHR17008"
] | [
"Meiosis_expr",
""
] | [
975,
940
] | 2 | [] | [] | [] | 0 | [
"2n2y",
"6ndu",
"6nep",
"6ucc"
] | 4 | [
"PUB00045952"
] | [
"1390336"
] | [
"Identification and characterization of the regulated pattern of expression of a novel mouse gene, meg1, during the meiotic cell cycle."
] | [
1992
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
976
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
4,
2,
3,
2
] | 4 | true | Family | Meiosis-expressed gene 1 protein | Meiosis-expressed gene 1 protein | Meiosis-expressed_gene_1 | 9 |
IPR020190 | 20,190 | Procorazonin | Procorazonin | Family | 264 | false | false | In Drosophila melanogaster (Fruit fly) the preprocorazonin consists of an 19 amino acid signal peptide, the 11 amino acid corazonin sequence followed by a 39 amino acid corazonin-precursor-related peptide (CPRP) and finally the 85 amino acid propeptide, [ ]. Corazonin is a cardioactive peptide of insects, which is prob... | [
"GO:0071858",
"GO:0045823"
] | [
"corazonin receptor binding",
"positive regulation of heart contraction"
] | [
"molecular_function",
"biological_process"
] | 2 | [
"PFAM"
] | [
"PF17308"
] | [
"Corazonin"
] | [
264
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00046093",
"PUB00046094",
"PUB00046095"
] | [
"7945373",
"15669053",
"17140699"
] | [
"Isolation and structure of the Drosophila corazonin gene.",
"Comparative analysis of Corazonin-encoding genes (Crz's) in Drosophila species and functional insights into Crz-expressing neurons.",
"Corazonin in insects."
] | [
1994,
2005,
2007
] | 3 | [] | [] | 0 | 0 | null | [
"Panarthropoda"
] | [
264
] | 1 | [
"Drosophila melanogaster"
] | [
1
] | 1 | true | Family | Procorazonin | Procorazonin | Procorazonin | 4 |
IPR020196 | 20,196 | Uncharacterised protein family YqgB | Uncharacterised_YqgB | Family | 542 | false | false | The yqgB and yqfZ genes are associated with the genomes of bacteria with distinct pathogenic properties and consequently fall into the category of being virulence genes [ ]. However, yqgB and yqfZ genes are not true virulence factors but instead are probably lifestyle determinant genes where the gene products act in co... | [] | [] | [] | 0 | [
"NCBIFAM",
"PFAM"
] | [
"NF033844",
"PF11036"
] | [
"small_YqgB",
"YqgB"
] | [
534,
542
] | 2 | [] | [] | [] | 0 | [] | 0 | [
"PUB00046098",
"PUB00046099"
] | [
"11445159",
"15294815"
] | [
"Bacterial virulence: can we draw the line?",
"Characterization of two Bacillus thuringiensis genes identified by in vivo screening of virulence factors."
] | [
2001,
2004
] | 2 | [] | [] | 0 | 0 | null | [
"Gammaproteobacteria"
] | [
542
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family YqgB | Uncharacterised protein family YqgB | Uncharacterised_YqgB | 4 |
IPR020201 | 20,201 | Autographa californica nuclear polyhedrosis virus (AcMNPV), Orf52 | AcMNPV_Orf52 | Family | 95 | false | false | This entry is represented by Autographa californica nuclear polyhedrosis virus (AcMNPV), Orf52; it is a family of uncharacterised viral proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11077"
] | [
"DUF2616"
] | [
95
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphabaculovirus"
] | [
95
] | 1 | [] | [] | 0 | true | Family | Autographa californica nuclear polyhedrosis virus (AcMNPV), Orf52 | Autographa californica nuclear polyhedrosis virus (AcMNPV), Orf52 | AcMNPV_Orf52 | 8 |
IPR020202 | 20,202 | Atracotoxin | Atracotoxin | Family | 219 | false | false | This entry represents various Atracotoxin proteins that are secreted from Hexathelidae (funnel-web tarantulas). They are thought not to be toxic to insects or mammals, having no effect on smooth muscle contractility [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17556"
] | [
"MIT_LIKE_ACTX"
] | [
219
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00046100"
] | [
"15979762"
] | [
"Discovery of an MIT-like atracotoxin family: spider venom peptides that share sequence homology but not pharmacological properties with AVIT family proteins."
] | [
2005
] | 1 | [] | [] | 0 | 0 | null | [
"Arthropoda"
] | [
219
] | 1 | [] | [] | 0 | true | Family | Atracotoxin | Atracotoxin | Atracotoxin | 2 |
IPR020203 | 20,203 | Membrane protein YneK | YneK | Family | 1,464 | false | false | This is a group of uncharacterised membrane bacterial proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11084"
] | [
"DUF2621"
] | [
1464
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Eukaryota",
"hydrothermal vent metagenome"
] | [
1460,
2,
2
] | 3 | [] | [] | 0 | true | Family | Membrane protein YneK | Membrane protein YneK | YneK | 4 |
IPR020204 | 20,204 | Uncharacterised protein family, YxaJ | Uncharacterised_YxaJ | Family | 158 | false | false | This entry represents a group of uncharacterised transmembrane proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17369"
] | [
"DUF5391"
] | [
158
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
158
] | 1 | [] | [] | 0 | true | Family | Uncharacterised protein family, YxaJ | Uncharacterised protein family, YxaJ | Uncharacterised_YxaJ | 5 |
IPR020205 | 20,205 | Uncharacterised protein family, YwnF, transmembrane | Uncharacterised_YwnF_TM | Family | 236 | false | false | This entry represents a group of uncharacterised transmembrane proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17370"
] | [
"DUF5392"
] | [
236
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacilli"
] | [
236
] | 1 | [] | [] | 0 | true | Family | Uncharacterised protein family, YwnF, transmembrane | Uncharacterised protein family, YwnF, transmembrane | Uncharacterised_YwnF_TM | 1 |
IPR020206 | 20,206 | Uncharacterised protein family, VP2110 | Uncharacterised_VP2110 | Family | 1,458 | false | false | This entry represents a group of uncharacterised proteins which includes Uncharacterized protein VP2110. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10952"
] | [
"DUF2753"
] | [
1458
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus thuringiensis phage MZTP02",
"Bacteria",
"Eukaryota",
"marine sediment metagenome"
] | [
1,
1442,
13,
2
] | 4 | [] | [] | 0 | true | Family | Uncharacterised protein family, VP2110 | Uncharacterised protein family, VP2110 | Uncharacterised_VP2110 | 8 |
IPR020207 | 20,207 | Metastasis-suppressor KiSS-1 | Metastasis-suppressor_KiSS-1 | Family | 304 | false | false | Kisspeptin (KiSS-1) is a metastasis suppressor protein found in malignant melanomas and in some breast cancers [ ]. KiSS-1 may regulate events downstream of cell-matrix adhesion, which could involve cytoskeletal reorganisation. KiSS-1 generates a C-terminally amidated peptide, metastin, which functions as the endogenou... | [] | [] | [] | 0 | [
"PFAM",
"PANTHER"
] | [
"PF15152",
"PTHR16955"
] | [
"Kisspeptin",
""
] | [
257,
284
] | 2 | [
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME",
"REACTOME"
] | [
"R-HSA-375276",
"R-HSA-416476",
"R-MMU-375276",
"R-MMU-416476",
"R-RNO-375276",
"R-RNO-416476"
] | [
"REACTOME:R-HSA-375276",
"REACTOME:R-HSA-416476",
"REACTOME:R-MMU-375276",
"REACTOME:R-MMU-416476",
"REACTOME:R-RNO-375276",
"REACTOME:R-RNO-416476"
] | 6 | [
"8xgs"
] | 1 | [
"PUB00045954",
"PUB00045955",
"PUB00045956",
"PUB00046119"
] | [
"18583061",
"16288036",
"17351756",
"15684075"
] | [
"The kisspeptin (KiSS-1)/GPR54 system in cancer biology.",
"Kisspeptin-10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a potential mechanism for the metastasis suppressor activity of kisspeptins.",
"Kisspeptins and the placenta: regulation of trophoblast invasion.",
... | [
2008,
2005,
2007,
2005
] | 4 | [] | [] | 0 | 0 | null | [
"Gnathostomata"
] | [
304
] | 1 | [
"Danio rerio",
"Homo sapiens",
"Mus musculus",
"Rattus norvegicus"
] | [
1,
1,
3,
3
] | 4 | true | Family | Metastasis-suppressor KiSS-1 | Metastasis-suppressor KiSS-1 | Metastasis-suppressor_KiSS-1 | 9 |
IPR020208 | 20,208 | Protein of unknown function DUF2712 | DUF2712 | Family | 394 | false | false | This entry represents a group of uncharacterised proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10916"
] | [
"DUF2712"
] | [
394
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati",
"Metamonada",
"human gut metagenome"
] | [
387,
6,
1
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF2712 | Protein of unknown function DUF2712 | DUF2712 | 1 |
IPR020209 | 20,209 | Cas6b, C-terminal domain | Cas6b_C | Domain | 386 | false | false | Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defence system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the i... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17262"
] | [
"Cas6b_C"
] | [
386
] | 1 | [] | [] | [] | 0 | [
"4z7k",
"4z7l"
] | 2 | [
"PUB00085160",
"PUB00085375",
"PUB00085376"
] | [
"28238733",
"25451598",
"26996962"
] | [
"Fragmentation of the CRISPR-Cas Type I-B signature protein Cas8b.",
"Crystal structure of the Csm3-Csm4 subcomplex in the type III-A CRISPR-Cas interference complex.",
"A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6."
] | [
2017,
2015,
2016
] | 3 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"metagenomes"
] | [
130,
229,
27
] | 3 | [] | [] | 0 | true | Domain | Cas6b, C-terminal domain | Cas6b, C-terminal domain | Cas6b_C | 9 |
IPR020210 | 20,210 | Uncharacterised protein family, YpbF, transmembrane | Uncharacterised_YpbF_TM | Family | 536 | false | false | This entry represents a group of uncharacterised transmembrane proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10864"
] | [
"DUF2663"
] | [
536
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati"
] | [
536
] | 1 | [] | [] | 0 | true | Family | Uncharacterised protein family, YpbF, transmembrane | Uncharacterised protein family, YpbF, transmembrane | Uncharacterised_YpbF_TM | 1 |
IPR020213 | 20,213 | Toxin coregulated pilus biosynthesis protein TcpS | Toxin-coreg_pilus_synth_TcpS | Family | 13 | false | false | Toxin coregulated pilus biosynthesis protein S (TcpS) is part of an operon associated with biosynthesis of the toxin coregulated pilus (TCP) of Vibrio cholerae [ ]. TCP is essential for successful colonisation of the bacteria in the small intestine. The genes tcpR, tcpD, tcpS, tcpT, tcpE and tcpF are organised to permi... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17456"
] | [
"TcpS"
] | [
13
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045958",
"PUB00045959"
] | [
"18462070",
"8097178"
] | [
"Distribution of genes for virulence and ecological fitness among diverse Vibrio cholerae population in a cholera endemic area: tracking the evolution of pathogenic strains.",
"Genetic organization and sequence of the promoter-distal region of the tcp gene cluster of Vibrio cholerae."
] | [
2008,
1993
] | 2 | [] | [] | 0 | 0 | null | [
"Vibrionaceae"
] | [
13
] | 1 | [] | [] | 0 | true | Family | Toxin coregulated pilus biosynthesis protein TcpS | Toxin coregulated pilus biosynthesis protein TcpS | Toxin-coreg_pilus_synth_TcpS | 3 |
IPR020214 | 20,214 | Cytomegalovirus UL124 | Cytomega_UL124 | Family | 49 | false | false | This is a family of unknown function found in cytomegalovirus. Family member UL124 is a predicted membrane glycoprotein with one predicted trans-membrane region [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17609"
] | [
"HCMV_UL124"
] | [
49
] | 1 | [
"REACTOME"
] | [
"R-HSA-9609690"
] | [
"REACTOME:R-HSA-9609690"
] | 1 | [] | 0 | [
"PUB00085213"
] | [
"22109557"
] | [
"High-resolution human cytomegalovirus transcriptome."
] | [
2011
] | 1 | [] | [] | 0 | 0 | null | [
"Cytomegalovirus"
] | [
49
] | 1 | [] | [] | 0 | true | Family | Cytomegalovirus UL124 | Cytomegalovirus UL124 | Cytomega_UL124 | 6 |
IPR020215 | 20,215 | EbsA-like | EbsA-like | Family | 1,019 | false | false | The pore-forming protein EbsA is one of three proteins (EbsA, EbsB, and EbsC) that affects the expression of a chromosomally encoded receptor, named binding substance (BS). In Enterococcus faecalis (Streptococcus faecalis), transfer of the conjugative plasmid pCF10 involves production of a plasmid-encoded aggregation s... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17255"
] | [
"EbsA"
] | [
1019
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00017205"
] | [
"8226689"
] | [
"Cloning and molecular analysis of genes affecting expression of binding substance, the recipient-encoded receptor(s) mediating mating aggregate formation in Enterococcus faecalis."
] | [
1993
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"human gut metagenome"
] | [
1018,
1
] | 2 | [] | [] | 0 | true | Family | EbsA-like | EbsA-like | EbsA-like | 1 |
IPR020216 | 20,216 | Uncharacterised protein family, YncE | Uncharacterised_YncE | Family | 396 | false | false | This entry represents a group of uncharacterised proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10903"
] | [
"DUF2691"
] | [
396
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillati",
"bioreactor metagenome"
] | [
394,
2
] | 2 | [] | [] | 0 | true | Family | Uncharacterised protein family, YncE | Uncharacterised protein family, YncE | Uncharacterised_YncE | 5 |
IPR020221 | 20,221 | Protein of unknown function DUF5505 | DUF5505 | Family | 37 | false | false | This is a family of unknown function found in Alphabaculovirus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17610"
] | [
"DUF5505"
] | [
37
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphabaculovirus"
] | [
37
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5505 | Protein of unknown function DUF5505 | DUF5505 | 3 |
IPR020226 | 20,226 | Avian adenovirus Orf17 | Avian_adenovirus_Orf17 | Family | 47 | false | false | This entry represents a group of uncharacterised proteins found in various avian (fowl) adenoviruses [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17611"
] | [
"DUF5506"
] | [
47
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00045963"
] | [
"19184805"
] | [
"Detection and differentiation of avian adenoviruses: a review."
] | [
2000
] | 1 | [] | [] | 0 | 0 | null | [
"Aviadenovirus"
] | [
47
] | 1 | [] | [] | 0 | true | Family | Avian adenovirus Orf17 | Avian adenovirus Orf17 | Avian_adenovirus_Orf17 | 3 |
IPR020227 | 20,227 | YpjCB-like, N-terminal domain | DUF5507 | Domain | 87 | false | false | This entry represents the N-terminal predicted domain is from the YpjCB family protein found in Enterobacteriaceae. It includes uncharacterised protein YpjC in which this domain is standalone. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17612"
] | [
"DUF5507"
] | [
87
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
87
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Domain | YpjCB-like, N-terminal domain | YpjCB-like, N-terminal domain | DUF5507 | 4 |
IPR020230 | 20,230 | Transcription regulator MotB | Tscrpt_reg_MotB | Family | 404 | false | false | This entry represents the transcription regulatory protein MotB, which is found in various Enterobacteria phages [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17613"
] | [
"motB"
] | [
404
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00085212"
] | [
"21507986"
] | [
"T4-Like genome organization of the Escherichia coli O157:H7 lytic phage AR1."
] | [
2011
] | 1 | [] | [] | 0 | 0 | null | [
"Salmonella dublin",
"Viruses"
] | [
1,
403
] | 2 | [] | [] | 0 | true | Family | Transcription regulator MotB | Transcription regulator MotB | Tscrpt_reg_MotB | 8 |
IPR020231 | 20,231 | Uncharacterised protein family, YfgI | Uncharacterised_YfgI | Family | 440 | false | false | This entry represents a group of uncharacterised proteins. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17358"
] | [
"DUF5384"
] | [
440
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Pseudomonadati",
"Punavirus",
"human gut metagenome"
] | [
434,
5,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family, YfgI | Uncharacterised protein family, YfgI | Uncharacterised_YfgI | 1 |
IPR020233 | 20,233 | GSE/EGO complex subunit Slm4 | Slm4 | Family | 114 | false | false | Budding yeast Slm4 is a component of both the GSE and the EGO complexes. The GSE (GAP1 Sorting in the Endosomes) complex is a GTPase complex required for intracellular sorting of Gap1 out of the endosome, which is required for the eventual delivery of GAP1 to the plasma membrane [ ]. The GSE complex is composed of two ... | [
"GO:0007165",
"GO:0071986"
] | [
"signal transduction",
"Ragulator complex"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM"
] | [
"PF16818"
] | [
"SLM4"
] | [
114
] | 1 | [] | [] | [] | 0 | [
"3lgo",
"4ftx",
"4fuw",
"4xpm",
"6jwp",
"9h4q",
"9h5k"
] | 7 | [
"PUB00045964",
"PUB00045965"
] | [
"16732272",
"15989961"
] | [
"A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.",
"The TOR and EGO protein complexes orchestrate microautophagy in yeast."
] | [
2006,
2005
] | 2 | [] | [] | 0 | 0 | null | [
"Saccharomycotina"
] | [
114
] | 1 | [
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
1
] | 1 | true | Family | GSE/EGO complex subunit Slm4 | GSE/EGO complex subunit Slm4 | Slm4 | 9 |
IPR020234 | 20,234 | Mite allergen, group-7 | Mite_allergen_group-7 | Family | 1,844 | false | false | This entry contains proteins that cause an allergic reaction in humans. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF16984"
] | [
"Grp7_allergen"
] | [
1844
] | 1 | [] | [] | [] | 0 | [
"3h4z",
"3uv1",
"9hae",
"9haf"
] | 4 | [
"PUB00075922"
] | [
"22970319"
] | [
"Crystal structure of Der f 7, a dust mite allergen from Dermatophagoides farinae."
] | [
2012
] | 1 | [] | [] | 0 | 0 | null | [
"Eukaryota"
] | [
1844
] | 1 | [
"Drosophila melanogaster"
] | [
3
] | 1 | true | Family | Mite allergen, group-7 | Mite allergen, group-7 | Mite_allergen_group-7 | 7 |
IPR020236 | 20,236 | Uncharacterised protein family YebF | Uncharacterised_YebF | Family | 491 | false | false | This entry represents a group of uncharacterised proteins. Though their function is not known, proteins in this family have been show to be secreted [ ]. | [] | [] | [] | 0 | [
"HAMAP"
] | [
"MF_01435"
] | [
"YebF"
] | [
491
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00053960"
] | [
"16369539"
] | [
"Extracellular accumulation of recombinant proteins fused to the carrier protein YebF in Escherichia coli."
] | [
2006
] | 1 | [
"IPR025603"
] | [] | 1 | 0 | 1 | [
"Bacteria"
] | [
491
] | 1 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family YebF | Uncharacterised protein family YebF | Uncharacterised_YebF | 5 |
IPR020239 | 20,239 | Protein of unknown function DUF5511 | DUF5511 | Family | 23 | false | false | This is a family of unknown function found in Bacillus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17630"
] | [
"DUF5511"
] | [
23
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
23
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5511 | Protein of unknown function DUF5511 | DUF5511 | 9 |
IPR020240 | 20,240 | Uncharacterised protein family UPF0412, YaaI | UPF0412_YaaI | Family | 1,128 | false | false | This entry represents proteins mainly found in gammaproteobacteria that have no known function. | [] | [] | [] | 0 | [
"HAMAP",
"NCBIFAM",
"PFAM"
] | [
"MF_01372",
"NF007541",
"PF10807"
] | [
"UPF0412",
"PRK10154.1",
"DUF2541"
] | [
586,
627,
1128
] | 3 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Protostomia",
"metagenomes"
] | [
1122,
2,
4
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family UPF0412, YaaI | Uncharacterised protein family UPF0412, YaaI | UPF0412_YaaI | 7 |
IPR020241 | 20,241 | Ribonuclease P/MRP subunit Pop7, fungi | RNase_P/MRP_Pop7_fungi | Family | 1,136 | false | false | Subunit Pop7 is a component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. It is also a component of RNase MRP, which cleaves pre-rRNA sequences [ , ]. In yeasts, RNase P consists of an RNA moiety and at least 9 protein subunits including Pop1, Pop3, Pop4, Pop5, Pop... | [
"GO:0001682",
"GO:0006396",
"GO:0000172",
"GO:0005655"
] | [
"tRNA 5'-leader removal",
"RNA processing",
"ribonuclease MRP complex",
"nucleolar ribonuclease P complex"
] | [
"biological_process",
"biological_process",
"cellular_component",
"cellular_component"
] | 4 | [
"PANTHER"
] | [
"PTHR28256"
] | [
""
] | [
1136
] | 1 | [] | [] | [] | 0 | [
"3iab",
"6agb",
"6ah3",
"6w6v",
"7c79",
"7c7a"
] | 6 | [
"PUB00045988",
"PUB00046121"
] | [
"9620854",
"9618478"
] | [
"Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.",
"Rpp2, an essential protein subunit of nuclear RNase P, is required for processing of precursor tRNAs and 35S precursor rRNA in Saccharomyces cerevisiae."
] | [
1998,
1998
] | 2 | [
"IPR014612"
] | [] | 1 | 0 | 1 | [
"Opisthokonta"
] | [
1136
] | 1 | [
"Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)",
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
1,
1
] | 2 | true | Family | Ribonuclease P/MRP subunit Pop7, fungi | Ribonuclease P/MRP subunit Pop7, fungi | RNase_P/MRP_Pop7_fungi | 3 |
IPR020242 | 20,242 | Conotoxin I2 | Conotoxin_I2 | Family | 158 | false | false | Members of this family display a XI cysteine pattern (C-C-CC-CC-C-C) and belong to the I2- superfamily conotoxins. Family members such as Kappa-conotoxin ViTx ( ) and Kappa-conotoxin SrXIA ( ) inhibit voltage gated potassium channels (Kv) [ ]. Cone snail toxins, conotoxins, are small peptides with disulphide connectivi... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17557"
] | [
"Conotoxin_I2"
] | [
158
] | 1 | [] | [] | [] | 0 | [
"9nvh"
] | 1 | [
"PUB00016617",
"PUB00016620",
"PUB00016662",
"PUB00085232"
] | [
"11478951",
"15225557",
"10903392",
"25522317"
] | [
"Cone venom--from accidental stings to deliberate injection.",
"Toxins in anti-nociception and anti-inflammation.",
"Conotoxins - new vistas for peptide therapeutics.",
"Conotoxin gene superfamilies."
] | [
2001,
2004,
2000,
2014
] | 4 | [] | [] | 0 | 0 | null | [
"Conoidea"
] | [
158
] | 1 | [] | [] | 0 | true | Family | Conotoxin I2 | Conotoxin I2 | Conotoxin_I2 | 2 |
IPR020244 | 20,244 | Rotavirus B, non-structural protein 5 | Rotavirus_B_NSP5 | Family | 110 | false | false | This entry represents non-structural protein 5 from rotaviruses. It is involved in genome replication, playing a crucial role in the formation of virus factories (viroplasms) which are large inclusions in the cytoplasm where core-like replication intermediates are assembled and RNA replication takes place. It forms a h... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17580"
] | [
"GBR_NSP5"
] | [
110
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Sedoreoviridae"
] | [
110
] | 1 | [] | [] | 0 | true | Family | Rotavirus B, non-structural protein 5 | Rotavirus B, non-structural protein 5 | Rotavirus_B_NSP5 | 2 |
IPR020246 | 20,246 | Uncharacterised protein family SCO3924 | Uncharacterised_SCO3924 | Family | 878 | false | false | This entry contains proteins that are confined to Streptomyces species. The protein family, which includes SCO3924, is currently uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17260"
] | [
"DUF5326"
] | [
878
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Actinomycetes"
] | [
878
] | 1 | [] | [] | 0 | true | Family | Uncharacterised protein family SCO3924 | Uncharacterised protein family SCO3924 | Uncharacterised_SCO3924 | 2 |
IPR020248 | 20,248 | MobB-Gp55 | MobB-Gp55 | Family | 222 | false | false | This entry represents Uncharacterized 8.5 kDa protein in mobB-Gp55 intergenic region and other uncharacterised proteins found in a number of T4-like bacteriophages. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17595"
] | [
"DUF5491"
] | [
222
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Viruses"
] | [
222
] | 1 | [] | [] | 0 | true | Family | MobB-Gp55 | MobB-Gp55 | MobB-Gp55 | 3 |
IPR020249 | 20,249 | Protein of unknown function DUF5492 | DUF5492 | Family | 12 | false | false | This is a family of unknown function found in Alphabaculovirus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17596"
] | [
"DUF5492"
] | [
12
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Alphabaculovirus"
] | [
12
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5492 | Protein of unknown function DUF5492 | DUF5492 | 1 |
IPR020250 | 20,250 | Uncharacterised protein family, plasmid pXO2-72 | Plasmid_pXO2-72 | Family | 99 | false | false | This is a family of unknown function mostly found in Bacilli. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17443"
] | [
"pXO2-72"
] | [
99
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillales"
] | [
99
] | 1 | [] | [] | 0 | true | Family | Uncharacterised protein family, plasmid pXO2-72 | Uncharacterised protein family, plasmid pXO2-72 | Plasmid_pXO2-72 | 2 |
IPR020251 | 20,251 | Uncharacterised protein family, YmjA | Uncharacterised_YmjA | Family | 491 | false | false | This entry contains proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10820"
] | [
"DUF2543"
] | [
491
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Opisthokonta",
"human gut metagenome"
] | [
488,
2,
1
] | 3 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family, YmjA | Uncharacterised protein family, YmjA | Uncharacterised_YmjA | 4 |
IPR020253 | 20,253 | Torovirus, nucleocapsid protein | Torovirus_nucleocapsid | Family | 71 | false | false | This entry represents the nucleocapsid protein from bovine, porcine and equine toroviruses. It is the major structural component of virions associating with the virion genomic RNA. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11030"
] | [
"Nucleocapsid-N"
] | [
71
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Eukaryota",
"Torovirus"
] | [
7,
64
] | 2 | [] | [] | 0 | true | Family | Torovirus, nucleocapsid protein | Torovirus, nucleocapsid protein | Torovirus_nucleocapsid | 8 |
IPR020255 | 20,255 | Minor curli fiber component A | CsgA | Family | 317 | false | false | Curli are extracellular functional amyloids that are assembled by enteric bacteria during biofilm formation and host colonization. The csg (curli specific gene) operon encodes major structural and accessory proteins that are required for curli production. The csgBAC operon encodes the major and minor curli fibre compon... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17334"
] | [
"CsgA"
] | [
317
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00091004",
"PUB00091005"
] | [
"25620560",
"21877724"
] | [
"The bacterial curli system possesses a potent and selective inhibitor of amyloid formation.",
"Fibrillation of the major curli subunit CsgA under a wide range of conditions implies a robust design of aggregation."
] | [
2015,
2011
] | 2 | [] | [] | 0 | 0 | null | [
"Bacteria"
] | [
317
] | 1 | [] | [] | 0 | true | Family | Minor curli fiber component A | Minor curli fiber component A | CsgA | 7 |
IPR020256 | 20,256 | Spore coat protein CotJA | Spore_coat_CotJA | Family | 2,199 | false | false | The open reading frame cotJA is part of the cotJ operon, which encodes spore coat proteins. Interaction of CotJA with CotJC is required for the assembly of both CotJA and CotJC into the spore coat [ ]. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11007"
] | [
"CotJA"
] | [
2199
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00055560"
] | [
"9364920"
] | [
"Assembly and interactions of cotJ-encoded proteins, constituents of the inner layers of the Bacillus subtilis spore coat."
] | [
1997
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"metagenomes"
] | [
2185,
14
] | 2 | [] | [] | 0 | true | Family | Spore coat protein CotJA | Spore coat protein CotJA | Spore_coat_CotJA | 9 |
IPR020257 | 20,257 | Protein of unknown function DUF5512 | DUF5512 | Family | 24 | false | false | This is a family of unknown function found in Bacillus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17631"
] | [
"DUF5512"
] | [
24
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillus cereus group"
] | [
24
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5512 | Protein of unknown function DUF5512 | DUF5512 | 2 |
IPR020258 | 20,258 | Uncharacterised protein family YbeF | Uncharacterised_YbeF | Family | 750 | false | false | This entry contains transmembrane proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10852"
] | [
"DUF2651"
] | [
750
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanocorpusculaceae",
"Siphoviridae sp. ctES717",
"metagenomes"
] | [
740,
4,
1,
5
] | 4 | [] | [] | 0 | true | Family | Uncharacterised protein family YbeF | Uncharacterised protein family YbeF | Uncharacterised_YbeF | 7 |
IPR020260 | 20,260 | Uncharacterised protein family YueH | Uncharacterised_YueH | Family | 423 | false | false | This entry contains proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF14166"
] | [
"YueH"
] | [
423
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"human gut metagenome"
] | [
422,
1
] | 2 | [] | [] | 0 | true | Family | Uncharacterised protein family YueH | Uncharacterised protein family YueH | Uncharacterised_YueH | 7 |
IPR020261 | 20,261 | Protein of unknown function DUF5493 | DUF5493 | Family | 19 | false | false | This is a family of unknown function mainly found in Sulfolobus viruses. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17597"
] | [
"DUF5493"
] | [
19
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Fuselloviridae",
"Sulfolobaceae"
] | [
9,
10
] | 2 | [] | [] | 0 | true | Family | Protein of unknown function DUF5493 | Protein of unknown function DUF5493 | DUF5493 | 9 |
IPR020262 | 20,262 | Uncharacterised protein family YecJ | Uncharacterised_YecJ | Family | 542 | false | false | This entry contains proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10964"
] | [
"DUF2766"
] | [
542
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Gammaproteobacteria",
"Lasius niger"
] | [
541,
1
] | 2 | [
"Escherichia coli (strain K12)"
] | [
1
] | 1 | true | Family | Uncharacterised protein family YecJ | Uncharacterised protein family YecJ | Uncharacterised_YecJ | 8 |
IPR020265 | 20,265 | Protein of unknown function DUF5513 | DUF5513 | Family | 26 | false | false | This is a family of unknown function found in Bacillus. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17632"
] | [
"DUF5513"
] | [
26
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
26
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF5513 | Protein of unknown function DUF5513 | DUF5513 | 9 |
IPR020266 | 20,266 | Mitochondrial import receptor subunit Tom6 | Tom6 | Family | 355 | false | false | Translocation of preproteins across the mitochondrial outer membrane is mediated by the translocase of the outer mitochondrial membrane (TOM) complex. Tom6 and Tom7, two small subunits of the TOM core are in direct contact with the major component of the pore, Tom40. In addition, Tom6 interacts with Tom22 in a manner t... | [
"GO:0030150",
"GO:0005742"
] | [
"protein import into mitochondrial matrix",
"mitochondrial outer membrane translocase complex"
] | [
"biological_process",
"cellular_component"
] | 2 | [
"PFAM"
] | [
"PF17112"
] | [
"Tom6"
] | [
355
] | 1 | [] | [] | [] | 0 | [
"6jnf",
"6ucu",
"6ucv",
"7e4i",
"8hco",
"8w5j",
"8w5k",
"8xkw",
"8xkx",
"8xky",
"9j99"
] | 11 | [
"PUB00045970",
"PUB00075722",
"PUB00075723"
] | [
"11278536",
"21765393",
"24781695"
] | [
"Assembly of Tom6 and Tom7 into the TOM core complex of Neurospora crassa.",
"Lateral release of proteins from the TOM complex into the outer membrane of mitochondria.",
"The presequence pathway is involved in protein sorting to the mitochondrial outer membrane."
] | [
2001,
2011,
2014
] | 3 | [] | [] | 0 | 0 | null | [
"Bacillota",
"Eukaryota"
] | [
4,
351
] | 2 | [
"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)"
] | [
1
] | 1 | true | Family | Mitochondrial import receptor subunit Tom6 | Mitochondrial import receptor subunit Tom6 | Tom6 | 4 |
IPR020269 | 20,269 | Releasin protein, Bacteriophage Mu | Phage_Mu_Releasin | Family | 858 | false | false | This family includes Releasin protein from phage Mu, also known as Gp25, which facilitates the release of the SAR-endolysin [ ]. The uncharacterised protein HI1498 from Haemophilus influenzae is also included in this entry. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10805"
] | [
"DUF2730"
] | [
858
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00101887"
] | [
"35471081"
] | [
"Endolysin Regulation in Phage Mu Lysis."
] | [
2022
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Caudoviricetes",
"Eukaryota",
"Thermoprotei",
"metagenomes"
] | [
832,
13,
2,
3,
8
] | 5 | [] | [] | 0 | true | Family | Releasin protein, Bacteriophage Mu | Releasin protein, Bacteriophage Mu | Phage_Mu_Releasin | 5 |
IPR020270 | 20,270 | Uncharacterised protein family, plasmid pXO2-34 | Plasmid_pXO2-34 | Family | 66 | false | false | This entry represents various hypothetical proteins from bacteria, and is confined to Bacillus. The protein Y6533 from Bacillus anthracis is encoded on plasmid pXO2 and is currently uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17362"
] | [
"pXO2-34"
] | [
66
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
66
] | 1 | [] | [] | 0 | true | Family | Uncharacterised protein family, plasmid pXO2-34 | Uncharacterised protein family, plasmid pXO2-34 | Plasmid_pXO2-34 | 9 |
IPR020271 | 20,271 | Uncharacterised protein family, MJ1172 | Uncharacterised_MJ1172 | Family | 854 | false | false | This entry includes the putative antitoxin RelB4 from Methanocaldococcus jannaschii (UniProt: Q58572). Most of the members in this entry are uncharacterised. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10884"
] | [
"DUF2683"
] | [
854
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Archaea",
"Bacteria",
"Daphnia magna",
"ecological metagenomes"
] | [
65,
783,
1,
5
] | 4 | [] | [] | 0 | true | Family | Uncharacterised protein family, MJ1172 | Uncharacterised protein family, MJ1172 | Uncharacterised_MJ1172 | 9 |
IPR020272 | 20,272 | Uncharacterized protein C-84-like | C-84-like | Family | 6 | false | false | This entry a family of uncharacterised protein found mainly in Sulfolobus viruses. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17598"
] | [
"DUF5494"
] | [
6
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Fuselloviridae",
"Sulfolobaceae"
] | [
4,
2
] | 2 | [] | [] | 0 | true | Family | Uncharacterized protein C-84-like | Uncharacterized protein C-84-like | C-84-like | 8 |
IPR020274 | 20,274 | Uncharacterised protein family HI1496 | Uncharacterised_HI1496 | Family | 119 | false | false | This entry contains membrane proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF10883"
] | [
"DUF2681"
] | [
119
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacteria",
"unclassified Caudoviricetes"
] | [
115,
4
] | 2 | [] | [] | 0 | true | Family | Uncharacterised protein family HI1496 | Uncharacterised protein family HI1496 | Uncharacterised_HI1496 | 5 |
IPR020275 | 20,275 | Protein of unknown function DUF5592 | DUF5592 | Family | 588 | false | false | This is a family of unknown function found in bacteria, including Uncharacterized protein pXO2-11/BXB0010/GBAA_pXO2_0010 (pXO2-11) [ ]. Family members contain two predicted trans-membrane regions. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17332"
] | [
"DUF5592"
] | [
588
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00162456"
] | [
"10475962"
] | [
"Sequence, assembly and analysis of pX01 and pX02."
] | [
1999
] | 1 | [] | [] | 0 | 0 | null | [
"Bacteria",
"Methanobrevibacter smithii",
"metagenomes"
] | [
585,
1,
2
] | 3 | [] | [] | 0 | true | Family | Protein of unknown function DUF5592 | Protein of unknown function DUF5592 | DUF5592 | 7 |
IPR020277 | 20,277 | Protein of unknown function DUF2624 | DUF2624 | Family | 796 | false | false | This entry contains proteins with no known function. | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF11116"
] | [
"DUF2624"
] | [
796
] | 1 | [] | [] | [] | 0 | [] | 0 | [] | [] | [] | [] | 0 | [] | [] | 0 | 0 | null | [
"Bacillota"
] | [
796
] | 1 | [] | [] | 0 | true | Family | Protein of unknown function DUF2624 | Protein of unknown function DUF2624 | DUF2624 | 1 |
IPR020278 | 20,278 | Small protein YqaH-like | YqaH-like | Family | 80 | false | false | This entry represents Small protein YqaH from Bacillus subtilis and similar sequences from Bacillales. YqaH binds to and counteracts DnaA replication initiation activity. Its overexpression decreases the number of replication initiation events. It also antagonizes DnaA's transcriptional regulation activity [ ]. This pr... | [] | [] | [] | 0 | [
"PFAM"
] | [
"PF17448"
] | [
"YqaH"
] | [
80
] | 1 | [] | [] | [] | 0 | [] | 0 | [
"PUB00056587",
"PUB00056588",
"PUB00160370"
] | [
"20889742",
"12060778",
"36748575"
] | [
"Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.",
"An expanded view of bacterial DNA replication.",
"Prophage-encoded small protein YqaH counteracts the activities of the replication initiator DnaA in <... | [
2010,
2002,
2022
] | 3 | [] | [] | 0 | 0 | null | [
"Bacillaceae",
"Caudoviricetes"
] | [
78,
2
] | 2 | [] | [] | 0 | true | Family | Small protein YqaH-like | Small protein YqaH-like | YqaH-like | 7 |
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