interpro_id
string
interpro_numeric_id
int64
name
string
short_name
string
entry_type
string
protein_count
int64
is_llm
bool
is_llm_reviewed
bool
abstract
string
go_ids
list
go_terms
list
go_categories
list
go_count
int64
member_databases
list
member_accessions
list
member_names
list
member_protein_counts
list
member_count
int64
external_databases
list
external_accessions
list
external_xrefs
list
external_xref_count
int64
pdb_ids
list
structure_count
int64
publication_ids
list
pubmed_ids
list
publication_titles
list
publication_years
list
publication_count
int64
parent_ids
list
child_ids
list
parent_count
int64
child_count
int64
tree_depth
float64
taxonomy_names
list
taxonomy_protein_counts
list
taxonomy_count
int64
key_species_names
list
key_species_protein_counts
list
key_species_count
int64
in_entry_list
bool
entry_list_type
string
entry_list_name
string
names_dat_name
string
short_names_dat_name
string
split_bucket
int64
IPR020108
20,108
Spore coat protein CotD
Spore_coat_CotD
Family
1,036
false
false
This entry represents spore coat protein D; a capsid protein involved in sporulation.
[]
[]
[]
0
[ "PFAM" ]
[ "PF11122" ]
[ "Spore-coat_CotD" ]
[ 1036 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillati" ]
[ 1036 ]
1
[]
[]
0
true
Family
Spore coat protein CotD
Spore coat protein CotD
Spore_coat_CotD
7
IPR020109
20,109
Holin, r1t-type
Holin_r1t
Family
1,122
false
false
Holin is a phage membrane protein that is necessary for host cell lysis. This entry contains holins related to the holin from Lactococcus phage r1t (Bacteriophage r1t) [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF16945" ]
[ "Phage_r1t_holin" ]
[ 1122 ]
1
[]
[]
[]
0
[]
0
[ "PUB00046143" ]
[ "12003945" ]
[ "Expression of Mycobacteriophage Ms6 lysis genes is driven by two sigma(70)-like promoters and is dependent on a transcription termination signal present in the leader RNA." ]
[ 2002 ]
1
[]
[]
0
0
null
[ "Bacteria", "Ecdysozoa", "Viruses", "metagenomes" ]
[ 689, 2, 423, 8 ]
4
[]
[]
0
true
Family
Holin, r1t-type
Holin, r1t-type
Holin_r1t
6
IPR020112
20,112
Protein of unknown function DUF2883
DUF2883
Family
42
false
false
This group of proteins currently have no known function and are found primarily in the T4-like bacteriophages.
[]
[]
[]
0
[ "PFAM" ]
[ "PF11097" ]
[ "DUF2883" ]
[ 42 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Tevenvirinae" ]
[ 42 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF2883
Protein of unknown function DUF2883
DUF2883
6
IPR020113
20,113
Protein of unknown function DUF5439
DUF5439
Family
14
false
false
This is a family of unknown function found in Orthopoxvirus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17507" ]
[ "DUF5439" ]
[ 14 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Orthopoxvirus" ]
[ 14 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5439
Protein of unknown function DUF5439
DUF5439
5
IPR020115
20,115
Anti-sigma-F factor Fin
Fin
Family
1,351
false
false
Fin (formerly known as YabK) is a small protein required for efficient switching from sigma(F)- to sigma(G)-directed gene expression during sporulation in Bacillus subtilis. Fin has been proposed to be an anti-sigma(F) factor which, by disabling sigma(F), promotes the switch to late developmental gene expression in the...
[ "GO:0010468" ]
[ "regulation of gene expression" ]
[ "biological_process" ]
1
[ "PFAM" ]
[ "PF10955" ]
[ "Fin" ]
[ 1351 ]
1
[]
[]
[]
0
[ "5msl" ]
1
[ "PUB00078865" ]
[ "21037003" ]
[ "A small protein required for the switch from {sigma}F to {sigma}G during sporulation in Bacillus subtilis." ]
[ 2011 ]
1
[]
[]
0
0
null
[ "Bacillota", "bioreactor metagenome" ]
[ 1348, 3 ]
2
[]
[]
0
true
Family
Anti-sigma-F factor Fin
Anti-sigma-F factor Fin
Fin
4
IPR020117
20,117
Uncharacterised protein family YncJ
Uncharacterised_YncJ
Family
648
false
false
This entry contains proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10829" ]
[ "DUF2554" ]
[ 648 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 648 ]
1
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Uncharacterised protein family YncJ
Uncharacterised protein family YncJ
Uncharacterised_YncJ
5
IPR020119
20,119
Pseudouridine synthase TruD, conserved site
PsdUridine_synth_TruD_CS
Conserved_site
9,348
false
false
Pseudouridine synthases catalyse the isomerisation of uridine to pseudouridine (Psi) in a variety of RNA molecules, and may function as RNA chaperones. Pseudouridine is the most abundant modified nucleotide found in all cellular RNAs. There are four distinct families of pseudouridine synthases that share no global sequ...
[ "GO:0003723", "GO:0009982", "GO:0001522", "GO:0009451" ]
[ "RNA binding", "pseudouridine synthase activity", "pseudouridine synthesis", "RNA modification" ]
[ "molecular_function", "molecular_function", "biological_process", "biological_process" ]
4
[ "PROSITE" ]
[ "PS01268" ]
[ "UPF0024" ]
[ 9348 ]
1
[ "EC", "REACTOME" ]
[ "5.4.99.27", "R-HSA-6782315" ]
[ "EC:5.4.99.27", "REACTOME:R-HSA-6782315" ]
2
[ "1sb7", "1si7", "1szw", "1z2z", "5kkp", "7mzv" ]
6
[ "PUB00014308", "PUB00015731", "PUB00015813", "PUB00045922", "PUB00092579" ]
[ "12756329", "15135053", "15208439", "10529181", "19664587" ]
[ "A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya.", "X-ray structure of tRNA pseudouridine synthase TruD reveals an inserted domain with a novel fold.", "Crystal structure of the highly divergent pseudouridine synthase TruD reveals a circular permutation of a...
[ 2003, 2004, 2004, 1999, 2009 ]
5
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Eukaryota", "unclassified sequences" ]
[ 755, 5400, 3129, 64 ]
4
[ "Caenorhabditis elegans", "Danio rerio", "Escherichia coli (strain K12)", "Homo sapiens", "Mus musculus", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)", "Schizosaccharomyces pombe (strain 972 / ATCC 24843)", "Zea mays" ]
[ 1, 7, 1, 4, 3, 8, 4, 1, 1, 19 ]
10
true
Conserved_site
Pseudouridine synthase TruD, conserved site
Pseudouridine synthase TruD, conserved site
PsdUridine_synth_TruD_CS
6
IPR020120
20,120
Plasmid pGKL2, Orf8
Plasmid_pGKL2_Orf8
Family
5
false
false
The proteins in this entry represent Orf8 from killer plasmid K2 (pGKL2) of Kluyveromyces lactis (Yeast) (Candida sphaerica). K2 contains ten open reading frames. Some of the ORFs overlap on different strands and some on the same strand and at least 8 of the 10 ORFs are transcribed. Comparison of the sequence of pGKL2 ...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17568" ]
[ "DUF5474" ]
[ 5 ]
1
[]
[]
[]
0
[]
0
[ "PUB00045923" ]
[ "3041369" ]
[ "Genome organization of the killer plasmid pGK12 from Kluyveromyces lactis." ]
[ 1988 ]
1
[]
[]
0
0
null
[ "Saccharomycotina" ]
[ 5 ]
1
[]
[]
0
true
Family
Plasmid pGKL2, Orf8
Plasmid pGKL2, Orf8
Plasmid_pGKL2_Orf8
4
IPR020121
20,121
Bacteriophage T7-like gene 6.5
Phage_T7-like_6.5
Family
441
false
false
The proteins in this entry are uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10911" ]
[ "T7-like_Y65" ]
[ 441 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Viruses" ]
[ 8, 433 ]
2
[]
[]
0
true
Family
Bacteriophage T7-like gene 6.5
Bacteriophage T7-like gene 6.5
Phage_T7-like_6.5
2
IPR020122
20,122
Alphabaculovirus, Y056
Alphabaculovirus_Y056
Family
49
false
false
This protein family contains uncharacterised proteins mainly found in Alphabaculovirus, including Uncharacterized 9.7 kDa protein from Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) and Uncharacterized 9.9 kDa protein in LEF8-FP intergenic region from Autographa californica nuclear polyhedrosis virus (AcM...
[]
[]
[]
0
[ "PFAM" ]
[ "PF10891" ]
[ "DUF2719" ]
[ 49 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Alphabaculovirus" ]
[ 49 ]
1
[]
[]
0
true
Family
Alphabaculovirus, Y056
Alphabaculovirus, Y056
Alphabaculovirus_Y056
1
IPR020123
20,123
Protein of unknown function DUF5475
DUF5475
Family
36
false
false
This is a family of unknown function found in Alphabaculovirus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17569" ]
[ "DUF5475" ]
[ 36 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Alphabaculovirus" ]
[ 36 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5475
Protein of unknown function DUF5475
DUF5475
8
IPR020125
20,125
Protein of unknown function DUF5488
DUF5488
Family
30
false
false
This is a family of unknown function found in Orthopoxvirus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17590" ]
[ "DUF5488" ]
[ 30 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Orthopoxvirus" ]
[ 30 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5488
Protein of unknown function DUF5488
DUF5488
7
IPR020126
20,126
Protein of unknown function DUF2732
DUF2732
Family
1,542
false
false
This entry represents a group of proteins with no known function
[]
[]
[]
0
[ "PFAM" ]
[ "PF10809" ]
[ "DUF2732" ]
[ 1542 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes", "Pseudomonadota", "metagenomes" ]
[ 69, 1470, 3 ]
3
[]
[]
0
true
Family
Protein of unknown function DUF2732
Protein of unknown function DUF2732
DUF2732
7
IPR020127
20,127
Colicin-E5 immunity protein
Colicin-E5_imm
Family
83
false
false
Colicins, which are produced by bacteria carrying the corresponding Col plasmids, kill sensitive Escherichia coli cells using different mechanisms. Colicin E5 is a tRNase toxin. The immunity protein ImmE5 is a specific inhibitor of colicin E5 that is expressed to protect the host cells. It binds to E5 C-terminal ribonu...
[ "GO:0030153" ]
[ "bacteriocin immunity" ]
[ "biological_process" ]
1
[ "PFAM" ]
[ "PF11480" ]
[ "ImmE5" ]
[ 83 ]
1
[]
[]
[]
0
[ "2dfx", "2fhz" ]
2
[ "PUB00040245", "PUB00040676" ]
[ "17099236", "16524591" ]
[ "Structural basis for sequence-dependent recognition of colicin E5 tRNase by mimicking the mRNA-tRNA interaction.", "Molecular basis of inhibition of the ribonuclease activity in colicin E5 by its cognate immunity protein." ]
[ 2006, 2006 ]
2
[]
[]
0
0
null
[ "Pseudomonadati" ]
[ 83 ]
1
[]
[]
0
true
Family
Colicin-E5 immunity protein
Colicin-E5 immunity protein
Colicin-E5_imm
6
IPR020128
20,128
Secapin
Secapin
Family
21
false
false
This entry represents Secapin; a nontoxic peptide found in the venom of bees and wasps, a serine protease inhibitor which exhibits antifibrinolytic, antielastolytic and antimicrobial activities against bacteria and fungi [ ]. It may function in the innate immune response to microbial infection and possibly in the venom...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17521" ]
[ "Secapin" ]
[ 21 ]
1
[]
[]
[]
0
[]
0
[ "PUB00045928", "PUB00097952", "PUB00097953" ]
[ "7213796", "27208884", "25017240" ]
[ "A comparative structural study of apamin and related bee venom peptides.", "Secapin, a bee venom peptide, exhibits anti-fibrinolytic, anti-elastolytic, and anti-microbial activities.", "Hyperalgesic and edematogenic effects of Secapin-2, a peptide isolated from Africanized honeybee (Apis mellifera) venom." ]
[ 1981, 2016, 2014 ]
3
[]
[]
0
0
null
[ "Endopterygota" ]
[ 21 ]
1
[]
[]
0
true
Family
Secapin
Secapin
Secapin
3
IPR020130
20,130
Spanin, outer lipoprotein subunit, T7likevirus
O-spanin_T7likevirus
Family
96
false
false
The lysis of Gram-negative hosts by double-strand DNA bacteriophages requires, in addition to the actions of a holin and endolysin, a third step involving the spanin complex. This complex consists of a small outer membrane lipoprotein and an integral cytoplasmic membrane protein, designated as o-spanins and i-spanins, ...
[ "GO:0019076" ]
[ "viral release from host cell" ]
[ "biological_process" ]
1
[ "PFAM" ]
[ "PF17531" ]
[ "O_Spanin_T7" ]
[ 96 ]
1
[]
[]
[]
0
[]
0
[ "PUB00082268" ]
[ "24585055" ]
[ "Phage lysis: three steps, three choices, one outcome." ]
[ 2014 ]
1
[]
[]
0
0
null
[ "Pseudomonas fildesensis", "Studiervirinae" ]
[ 1, 95 ]
2
[]
[]
0
true
Family
Spanin, outer lipoprotein subunit, T7likevirus
Spanin, outer lipoprotein subunit, T7likevirus
O-spanin_T7likevirus
1
IPR020132
20,132
Mycobacteriophage tail assembly protein 24/25
Gp24/Gp25
Family
774
false
false
This entry includes the tail assembly protein Gp24 and Gp25. In some strains Gp24 is the N-terminal domain of a fusion protein with the following ORF, Gp25. In Mycobacteriophages these proteins are likely to interact with the tape measure protein [ , ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF17388" ]
[ "GP24_25" ]
[ 774 ]
1
[]
[]
[]
0
[]
0
[ "PUB00098615", "PUB00098616" ]
[ "26713219", "30291704" ]
[ "Mycobacteriophage cell binding proteins for the capture of mycobacteria.", "Mycobacteriophages." ]
[ 2014, 2018 ]
2
[]
[]
0
0
null
[ "Bacteria", "Viruses" ]
[ 71, 703 ]
2
[]
[]
0
true
Family
Mycobacteriophage tail assembly protein 24/25
Mycobacteriophage tail assembly protein 24/25
Gp24/Gp25
2
IPR020133
20,133
Decidual protein, progesterone induced
DEPP
Family
452
false
false
This entry represents proteins from various mammals known as DEPP proteins, which are decidual proteins induced by progesterone. Decidualization of the endometrial stromal cells (ESC) is thought to be stimulated by progesterone and/or cAMP and is crucial for embryo implantation and placentation. Increased expression of...
[]
[]
[]
0
[ "PFAM", "PANTHER" ]
[ "PF15343", "PTHR15426" ]
[ "DEPP", "" ]
[ 260, 442 ]
2
[]
[]
[]
0
[]
0
[ "PUB00045931" ]
[ "16123073" ]
[ "A novel protein Depp, which is induced by progesterone in human endometrial stromal cells activates Elk-1 transcription factor." ]
[ 2005 ]
1
[]
[]
0
0
null
[ "Gnathostomata" ]
[ 452 ]
1
[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 4, 3, 2, 3 ]
4
true
Family
Decidual protein, progesterone induced
Decidual protein, progesterone induced
DEPP
9
IPR020134
20,134
Bacteriophage T7-like, protein 6.7
Phage_T7-like_6.7
Family
411
false
false
Protein 6.7 is ejected from the infecting virion. It is found in tail-less particles and has been defined as a head protein [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF17570" ]
[ "T7-like_gp67" ]
[ 411 ]
1
[]
[]
[]
0
[ "9jyy", "9jyz", "9jz0", "9vvp" ]
4
[ "PUB00055981" ]
[ "16054667" ]
[ "Changes in bacteriophage T7 virion structure at the initiation of infection." ]
[ 2005 ]
1
[]
[]
0
0
null
[ "Bacteria", "Viruses" ]
[ 7, 404 ]
2
[]
[]
0
true
Family
Bacteriophage T7-like, protein 6.7
Bacteriophage T7-like, protein 6.7
Phage_T7-like_6.7
2
IPR020135
20,135
Uncharacterised protein family RP854
Uncharacterised_RP854
Family
47
false
false
This entry represents proteins related to RP854 from Rickettsia prowazekii. They are currently uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17460" ]
[ "RP854" ]
[ 47 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Oppiella nova", "Rickettsiaceae" ]
[ 1, 46 ]
2
[]
[]
0
true
Family
Uncharacterised protein family RP854
Uncharacterised protein family RP854
Uncharacterised_RP854
4
IPR020138
20,138
Uncharacterised protein family YqzF
Uncharacterised_YqzF
Family
1,404
false
false
This entry represents uncharacterised membrane proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF11118" ]
[ "DUF2627" ]
[ 1404 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 1404 ]
1
[]
[]
0
true
Family
Uncharacterised protein family YqzF
Uncharacterised protein family YqzF
Uncharacterised_YqzF
3
IPR020139
20,139
Protein of unknown function DUF2642
DUF2642
Family
910
false
false
This entry contains proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10842" ]
[ "DUF2642" ]
[ 910 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillati" ]
[ 910 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF2642
Protein of unknown function DUF2642
DUF2642
6
IPR020141
20,141
Herpesvirus UL41A
Herpesvirus_UL41A
Family
19
false
false
This entry represents proteins from Herpesvirus. The protein UL41A is thought to be a membrane associated glycoprotein but is currently uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17591" ]
[ "UL41A" ]
[ 19 ]
1
[ "REACTOME" ]
[ "R-HSA-9610379" ]
[ "REACTOME:R-HSA-9610379" ]
1
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Cytomegalovirus" ]
[ 19 ]
1
[]
[]
0
true
Family
Herpesvirus UL41A
Herpesvirus UL41A
Herpesvirus_UL41A
6
IPR020142
20,142
Protein of unknown function DUF5489
DUF5489
Family
15
false
false
This is a family of unknown function found in Alphafusellovirus including Uncharacterized protein B-78. This entry includes some uncharacterised archaeal proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17592" ]
[ "DUF5489" ]
[ 15 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Alphafusellovirus", "Sulfolobaceae" ]
[ 7, 8 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF5489
Protein of unknown function DUF5489
DUF5489
1
IPR020144
20,144
Stage V sporulation protein AB
SpoVAB
Family
1,642
false
false
This entry represents stage V sporulation protein AB (SpoVAB), which is involved in spore germination and is located in the spores' inner membrane. In Bacillus subtilis, SpoVA proteins are a component of a dipicolinic acid (DPA) channel in the spore's inner membrane and are involved in DPA release [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF13782" ]
[ "SpoVAB" ]
[ 1642 ]
1
[]
[]
[]
0
[]
0
[ "PUB00045929" ]
[ "17718850" ]
[ "Studies of the release of small molecules during pressure germination of spores of Bacillus subtilis." ]
[ 2007 ]
1
[]
[]
0
0
null
[ "Bacillati", "metagenomes" ]
[ 1639, 3 ]
2
[]
[]
0
true
Family
Stage V sporulation protein AB
Stage V sporulation protein AB
SpoVAB
1
IPR020147
20,147
Inhibitor of dGTPase, bacteriophage T7-like
Phage_T7-like_1.2
Family
174
false
false
The T7-like bacteriophage gene 1.2 protein is an inhibitor of the Escherichia coli dGTP triphosphohydrolase (dGTPase) and is implicated in DNA replication.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10922" ]
[ "T7-like_gp12" ]
[ 174 ]
1
[]
[]
[]
0
[ "2mdp", "7u65", "7u66", "7u67" ]
4
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Caudoviricetes", "Eumeta variegata" ]
[ 173, 1 ]
2
[]
[]
0
true
Family
Inhibitor of dGTPase, bacteriophage T7-like
Inhibitor of dGTPase, bacteriophage T7-like
Phage_T7-like_1.2
7
IPR020148
20,148
Protein of unknown function DUF5477
DUF5477
Family
14
false
false
This is a family of proteins of unknown function found in phages.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17571" ]
[ "DUF5477" ]
[ 14 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Studiervirinae" ]
[ 14 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5477
Protein of unknown function DUF5477
DUF5477
3
IPR020149
20,149
Uncharacterised protein family C02F5.10
Uncharacterised_C02F5.10
Family
119
false
false
The proteins in this entry are uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17309" ]
[ "DUF5356" ]
[ 119 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Rhabditida" ]
[ 119 ]
1
[ "Caenorhabditis elegans" ]
[ 2 ]
1
true
Family
Uncharacterised protein family C02F5.10
Uncharacterised protein family C02F5.10
Uncharacterised_C02F5.10
9
IPR020150
20,150
Type IV conjugative transfer system protein TrbE
T4SS_TrbE
Family
445
false
false
TrbE is encoded by the F-plasmid and is located between traN and traF. The product of trbE is a small, integral, inner membrane protein. Mutation of trbE by insertional mutagenesis suggests that TrbE is not essential for F transfer from Escherichia coli (strain K12) under standard mating conditions [ ].
[]
[]
[]
0
[ "NCBIFAM", "PFAM" ]
[ "NF010271", "PF11100" ]
[ "PRK13718.1", "TrbE" ]
[ 394, 445 ]
2
[]
[]
[]
0
[]
0
[ "PUB00020464" ]
[ "1593622" ]
[ "Characterization of the F plasmid mating aggregation gene traN and of a new F transfer region locus trbE." ]
[ 1992 ]
1
[]
[]
0
0
null
[ "Bacteria" ]
[ 445 ]
1
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Type IV conjugative transfer system protein TrbE
Type IV conjugative transfer system protein TrbE
T4SS_TrbE
7
IPR020151
20,151
Protein of unknown function DUF5478
DUF5478
Family
44
false
false
This is a family of unknown function found in Alphabaculovirus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17572" ]
[ "DUF5478" ]
[ 44 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Alphabaculovirus" ]
[ 44 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5478
Protein of unknown function DUF5478
DUF5478
7
IPR020155
20,155
Uncharacterised protein family YeiS
Uncharacterised_YeiS
Family
700
false
false
This entry represents transmembrane proteins with no known function.
[ "GO:0016020" ]
[ "membrane" ]
[ "cellular_component" ]
1
[ "PFAM" ]
[ "PF10808" ]
[ "DUF2542" ]
[ 700 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Pseudomonadota" ]
[ 700 ]
1
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Uncharacterised protein family YeiS
Uncharacterised protein family YeiS
Uncharacterised_YeiS
7
IPR020156
20,156
Protein of unknown function DUF5490
DUF5490
Family
171
false
false
This is a family of unknown function found mainly in Straboviridae. This entry includes Uncharacterized 9.2 kDa protein in Gp55-nrdG intergenic region.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17593" ]
[ "DUF5490" ]
[ 171 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viruses" ]
[ 171 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5490
Protein of unknown function DUF5490
DUF5490
7
IPR020157
20,157
Uncharacterised protein family YqkC
Uncharacterised_YqkC
Family
272
false
false
This entry contains proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10827" ]
[ "DUF2552" ]
[ 272 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillales" ]
[ 272 ]
1
[]
[]
0
true
Family
Uncharacterised protein family YqkC
Uncharacterised protein family YqkC
Uncharacterised_YqkC
5
IPR020158
20,158
Protein of unknown function DUF2756
DUF2756
Family
1,030
false
false
This entry contains proteins with no known function.
[]
[]
[]
0
[ "NCBIFAM", "PFAM" ]
[ "NF007675", "PF10956" ]
[ "PRK10350.1", "DUF2756" ]
[ 868, 1030 ]
2
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Seminavis robusta", "human gut metagenome" ]
[ 1028, 1, 1 ]
3
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Protein of unknown function DUF2756
Protein of unknown function DUF2756
DUF2756
8
IPR020159
20,159
Tail fiber assembly helper protein
Gp57
Family
195
false
false
Tail fiber assembly helper protein (Gp57) is a chaperone protein for short tail fibre phage protein, that acts as a molecular chaperone of gp12, increasing the folding efficacy and production efficiency [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF17594" ]
[ "GP57" ]
[ 195 ]
1
[]
[]
[]
0
[]
0
[ "PUB00085214" ]
[ "27471503" ]
[ "T4 Phage Tail Adhesin Gp12 Counteracts LPS-Induced Inflammation In Vivo." ]
[ 2016 ]
1
[]
[]
0
0
null
[ "Viruses" ]
[ 195 ]
1
[]
[]
0
true
Family
Tail fiber assembly helper protein
Tail fiber assembly helper protein
Gp57
5
IPR020162
20,162
Cell cycle exit/neuronal differentiation protein 1
Cend1
Family
618
false
false
Cell cycle exit and neuronal differentiation protein 1 (Cend1 or BM88) is a homodimer of 140 amino acids. It has a putative transmembrane domain at the C terminus. The mRNA of this protein is expressed only in neural tissues, where it is restricted to neurons. It is involved in neuroblastoma cell differentiation [ , ],...
[ "GO:0021549", "GO:0030182" ]
[ "cerebellum development", "neuron differentiation" ]
[ "biological_process", "biological_process" ]
2
[ "PFAM", "PANTHER" ]
[ "PF15677", "PTHR36683" ]
[ "CEND1", "" ]
[ 618, 564 ]
2
[]
[]
[]
0
[]
0
[ "PUB00045934", "PUB00075747", "PUB00075748", "PUB00075749" ]
[ "7775480", "20153830", "23658157", "24312406" ]
[ "The BM88 antigen, a novel neuron-specific molecule, enhances the differentiation of mouse neuroblastoma cells.", "Impaired cerebellar development and deficits in motor coordination in mice lacking the neuronal protein BM88/Cend1.", "Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuron...
[ 1995, 2010, 2013, 2013 ]
4
[]
[]
0
0
null
[ "Gnathostomata" ]
[ 618 ]
1
[ "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 2, 1, 2 ]
3
true
Family
Cell cycle exit/neuronal differentiation protein 1
Cell cycle exit/neuronal differentiation protein 1
Cend1
4
IPR020164
20,164
Cytochrome c oxidase assembly protein COX16
Cyt_c_Oxase_assmbl_COX16
Family
3,473
false
false
Cytochrome c oxidase assembly protein COX16 is required for the assembly of cytochrome c oxidase [ ]. It is found in the inner membrane of the mitochondrion.
[ "GO:0031966" ]
[ "mitochondrial membrane" ]
[ "cellular_component" ]
1
[ "PFAM" ]
[ "PF14138" ]
[ "COX16" ]
[ 3473 ]
1
[ "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]
[ "R-BTA-9864848", "R-CEL-9864848", "R-HSA-9864848", "R-MMU-9864848" ]
[ "REACTOME:R-BTA-9864848", "REACTOME:R-CEL-9864848", "REACTOME:R-HSA-9864848", "REACTOME:R-MMU-9864848" ]
4
[]
0
[ "PUB00057336" ]
[ "12446688" ]
[ "COX16 encodes a novel protein required for the assembly of cytochrome oxidase in Saccharomyces cerevisiae." ]
[ 2003 ]
1
[]
[]
0
0
null
[ "Eukaryota" ]
[ 3473 ]
1
[ "Arabidopsis thaliana", "Caenorhabditis elegans", "Danio rerio", "Drosophila melanogaster", "Homo sapiens", "Mus musculus", "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Oryza sativa subsp. japonica", "Rattus norvegicus", "Saccharomyces cerevisiae (strai...
[ 2, 2, 1, 3, 4, 8, 1, 3, 3, 1, 1, 3 ]
12
true
Family
Cytochrome c oxidase assembly protein COX16
Cytochrome c oxidase assembly protein COX16
Cyt_c_Oxase_assmbl_COX16
7
IPR020168
20,168
Uncharacterised protein family RP363/RP364
Uncharacterised_RP363/RP364
Family
86
false
false
This entry represents proteins that are confined to Rickettsiales. The proteins include RP363 and RP364, which are currently uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17422" ]
[ "DUF5410" ]
[ 86 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Pseudolycoriella hygida", "Rickettsia" ]
[ 1, 85 ]
2
[]
[]
0
true
Family
Uncharacterised protein family RP363/RP364
Uncharacterised protein family RP363/RP364
Uncharacterised_RP363/RP364
4
IPR020169
20,169
Intrinsic membrane protein family, PufX
Intrinsic_membrane_PufX
Family
95
false
false
PufX organises RC-LH1, the photosynthesis reaction centre-light harvesting complex 1 core complex of Rhodobacter sphaeroides [ ]. It also facilitates the exchange of quinol for quinone between the reaction centre and cytochrome bc(1) complexes. In organic solvent, PufX contains two hydrophobic helices which are flanked...
[]
[]
[]
0
[ "PFAM" ]
[ "PF11511" ]
[ "RhodobacterPufX" ]
[ 95 ]
1
[]
[]
[]
0
[ "2dw3", "2ita", "2nrg", "4v9g", "7ddq", "7f0l", "7pil", "7pqd", "7va9", "7vb9", "7vnm", "7vny", "7vor", "7vot", "7vy2", "7vy3", "7yml", "8b64", "8ygd", "8ygl" ]
20
[ "PUB00041775" ]
[ "17161397" ]
[ "The solution structure of the PufX polypeptide from Rhodobacter sphaeroides." ]
[ 2006 ]
1
[]
[]
0
0
null
[ "Pseudomonadota" ]
[ 95 ]
1
[]
[]
0
true
Family
Intrinsic membrane protein family, PufX
Intrinsic membrane protein family, PufX
Intrinsic_membrane_PufX
6
IPR020170
20,170
Herpesvirus UL11, muromegalovirus/roseolovirus-type
Herpes_UL11_megaloV/roseoloV
Family
39
false
false
UL11 (also known as cytoplasmic envelopment protein 3) is conserved throughout the herpesvirus family. It is a membrane-associated tegument protein that is incorporated into the HSV virion. UL11 and UL51, either singly or in combination, are involved in virion envelopment and/or egress. Both proteins are fatty acylated...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17474" ]
[ "U71" ]
[ 39 ]
1
[]
[]
[]
0
[]
0
[ "PUB00045941", "PUB00085328" ]
[ "17694428", "23152545" ]
[ "Herpes simplex virus protein UL11 but not UL51 is associated with lipid rafts.", "Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation." ]
[ 2007, 2013 ]
2
[ "IPR034705" ]
[]
1
0
1
[ "Betaherpesvirinae", "Homo sapiens" ]
[ 38, 1 ]
2
[ "Homo sapiens" ]
[ 1 ]
1
true
Family
Herpesvirus UL11, muromegalovirus/roseolovirus-type
Herpesvirus UL11, muromegalovirus/roseolovirus-type
Herpes_UL11_megaloV/roseoloV
8
IPR020171
20,171
Uncharacterised protein family RC0039
Uncharacterised_RC0039
Family
62
false
false
This entry represents proteins that are confined to Rickettsiales. The proteins, which include RC0039 and RP030, are currently uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17372" ]
[ "DUF5394" ]
[ 62 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Arthropoda", "Rickettsiales" ]
[ 2, 60 ]
2
[]
[]
0
true
Family
Uncharacterised protein family RC0039
Uncharacterised protein family RC0039
Uncharacterised_RC0039
5
IPR020180
20,180
Uncharacterised protein family RP853
Uncharacterised_RP853
Family
48
false
false
This entry represents proteins that are confined to Rickettsia. The family member RP853 is thought to be a transmembrane protein, but is currently uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17542" ]
[ "RP853" ]
[ 48 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Oppiella nova", "Rickettsiaceae" ]
[ 1, 47 ]
2
[]
[]
0
true
Family
Uncharacterised protein family RP853
Uncharacterised protein family RP853
Uncharacterised_RP853
6
IPR020181
20,181
Ant venom allergen, Sol i 2
Ant_venom_allergen_Sol_i_2
Family
11
false
false
Fire ant venom from Solenopsis invicta (Red imported fire ant), is an extremely potent allergy-inducing agent containing four major allergens, Sol i 1 to Sol i 4 [ , ]. This family contains the allergens Sol i 2. Sol i 2 causes IgE antibody production in about one-third of individuals stung by fire ants. This allergen ...
[]
[]
[]
0
[ "CDD" ]
[ "cd12800" ]
[ "Sol_i_2" ]
[ 11 ]
1
[]
[]
[]
0
[ "2ygu" ]
1
[ "PUB00057651", "PUB00080438", "PUB00080439" ]
[ "22100449", "3192865", "8423273" ]
[ "Crystal structure of sol I 2: a major allergen from fire ant venom.", "Allergens in Hymenoptera venom. XX. Isolation of four allergens from imported fire ant (Solenopsis invicta) venom.", "Allergens in Hymenoptera venom XXIV: the amino acid sequences of imported fire ant venom allergens Sol i II, Sol i III, an...
[ 2012, 1988, 1993 ]
3
[]
[]
0
0
null
[ "Solenopsis" ]
[ 11 ]
1
[]
[]
0
true
Family
Ant venom allergen, Sol i 2
Ant venom allergen, Sol i 2
Ant_venom_allergen_Sol_i_2
8
IPR020182
20,182
Protein of unknown function DUF5460
DUF5460
Family
44
false
false
This is a family of unknown function found in Rickettsia. Family members are predicted to contain one trans-membrane region.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17544" ]
[ "DUF5460" ]
[ 44 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bemisia tabaci", "Rickettsia" ]
[ 1, 43 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF5460
Protein of unknown function DUF5460
DUF5460
9
IPR020183
20,183
Uncharacterised protein family RC0048
Uncharacterised_RC0048
Family
62
false
false
This entry represents proteins that are mainly confined to Rickettsia and Orientia. The proteins, which include RP364 and RC0048, are currently uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10871" ]
[ "DUF2748" ]
[ 62 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota", "Rickettsiales" ]
[ 2, 60 ]
2
[]
[]
0
true
Family
Uncharacterised protein family RC0048
Uncharacterised protein family RC0048
Uncharacterised_RC0048
9
IPR020184
20,184
Keratin-associated protein 7
KRTAP7
Family
135
false
false
This family includes keratin-associated protein 7-1, a member of the type 7 family. In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft throug...
[]
[]
[]
0
[ "PFAM", "PANTHER" ]
[ "PF15034", "PTHR38504" ]
[ "KRTAP7", "" ]
[ 135, 135 ]
2
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Mammalia" ]
[ 135 ]
1
[ "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 1, 1, 1 ]
3
true
Family
Keratin-associated protein 7
Keratin-associated protein 7
KRTAP7
8
IPR020185
20,185
Spore morphogenesis/germination protein YwcE
Spore_morphogenesis_YwcE
Family
158
false
false
Spore morphogenesis and germination protein YwcE is required for proper spore morphogenesis and germination. It is repressed by abrB during growth and activated at the onset of sporulation in a spo0A-dependent manner. This protein has similar features to holin [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF17368" ]
[ "YwcE" ]
[ 158 ]
1
[]
[]
[]
0
[]
0
[ "PUB00045951" ]
[ "16159778" ]
[ "A gene encoding a holin-like protein involved in spore morphogenesis and spore germination in Bacillus subtilis." ]
[ 2005 ]
1
[]
[]
0
0
null
[ "Bacillales" ]
[ 158 ]
1
[]
[]
0
true
Family
Spore morphogenesis/germination protein YwcE
Spore morphogenesis/germination protein YwcE
Spore_morphogenesis_YwcE
5
IPR020186
20,186
Meiosis-expressed gene 1 protein
Meiosis-expressed_gene_1
Family
976
false
false
This entry represents Meiosis-expressed gene 1 protein and its homologues, encoded by the gene MEIG1. It may be involved in germ cell differentiation during meiotic prophase. Sequence analysis predicts this protein to be 10.8kDa in size and to be highly charged and lysine rich [ ].
[ "GO:0005634" ]
[ "nucleus" ]
[ "cellular_component" ]
1
[ "PFAM", "PANTHER" ]
[ "PF15163", "PTHR17008" ]
[ "Meiosis_expr", "" ]
[ 975, 940 ]
2
[]
[]
[]
0
[ "2n2y", "6ndu", "6nep", "6ucc" ]
4
[ "PUB00045952" ]
[ "1390336" ]
[ "Identification and characterization of the regulated pattern of expression of a novel mouse gene, meg1, during the meiotic cell cycle." ]
[ 1992 ]
1
[]
[]
0
0
null
[ "Eukaryota" ]
[ 976 ]
1
[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 4, 2, 3, 2 ]
4
true
Family
Meiosis-expressed gene 1 protein
Meiosis-expressed gene 1 protein
Meiosis-expressed_gene_1
9
IPR020190
20,190
Procorazonin
Procorazonin
Family
264
false
false
In Drosophila melanogaster (Fruit fly) the preprocorazonin consists of an 19 amino acid signal peptide, the 11 amino acid corazonin sequence followed by a 39 amino acid corazonin-precursor-related peptide (CPRP) and finally the 85 amino acid propeptide, [ ]. Corazonin is a cardioactive peptide of insects, which is prob...
[ "GO:0071858", "GO:0045823" ]
[ "corazonin receptor binding", "positive regulation of heart contraction" ]
[ "molecular_function", "biological_process" ]
2
[ "PFAM" ]
[ "PF17308" ]
[ "Corazonin" ]
[ 264 ]
1
[]
[]
[]
0
[]
0
[ "PUB00046093", "PUB00046094", "PUB00046095" ]
[ "7945373", "15669053", "17140699" ]
[ "Isolation and structure of the Drosophila corazonin gene.", "Comparative analysis of Corazonin-encoding genes (Crz's) in Drosophila species and functional insights into Crz-expressing neurons.", "Corazonin in insects." ]
[ 1994, 2005, 2007 ]
3
[]
[]
0
0
null
[ "Panarthropoda" ]
[ 264 ]
1
[ "Drosophila melanogaster" ]
[ 1 ]
1
true
Family
Procorazonin
Procorazonin
Procorazonin
4
IPR020196
20,196
Uncharacterised protein family YqgB
Uncharacterised_YqgB
Family
542
false
false
The yqgB and yqfZ genes are associated with the genomes of bacteria with distinct pathogenic properties and consequently fall into the category of being virulence genes [ ]. However, yqgB and yqfZ genes are not true virulence factors but instead are probably lifestyle determinant genes where the gene products act in co...
[]
[]
[]
0
[ "NCBIFAM", "PFAM" ]
[ "NF033844", "PF11036" ]
[ "small_YqgB", "YqgB" ]
[ 534, 542 ]
2
[]
[]
[]
0
[]
0
[ "PUB00046098", "PUB00046099" ]
[ "11445159", "15294815" ]
[ "Bacterial virulence: can we draw the line?", "Characterization of two Bacillus thuringiensis genes identified by in vivo screening of virulence factors." ]
[ 2001, 2004 ]
2
[]
[]
0
0
null
[ "Gammaproteobacteria" ]
[ 542 ]
1
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Uncharacterised protein family YqgB
Uncharacterised protein family YqgB
Uncharacterised_YqgB
4
IPR020201
20,201
Autographa californica nuclear polyhedrosis virus (AcMNPV), Orf52
AcMNPV_Orf52
Family
95
false
false
This entry is represented by Autographa californica nuclear polyhedrosis virus (AcMNPV), Orf52; it is a family of uncharacterised viral proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF11077" ]
[ "DUF2616" ]
[ 95 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Alphabaculovirus" ]
[ 95 ]
1
[]
[]
0
true
Family
Autographa californica nuclear polyhedrosis virus (AcMNPV), Orf52
Autographa californica nuclear polyhedrosis virus (AcMNPV), Orf52
AcMNPV_Orf52
8
IPR020202
20,202
Atracotoxin
Atracotoxin
Family
219
false
false
This entry represents various Atracotoxin proteins that are secreted from Hexathelidae (funnel-web tarantulas). They are thought not to be toxic to insects or mammals, having no effect on smooth muscle contractility [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF17556" ]
[ "MIT_LIKE_ACTX" ]
[ 219 ]
1
[]
[]
[]
0
[]
0
[ "PUB00046100" ]
[ "15979762" ]
[ "Discovery of an MIT-like atracotoxin family: spider venom peptides that share sequence homology but not pharmacological properties with AVIT family proteins." ]
[ 2005 ]
1
[]
[]
0
0
null
[ "Arthropoda" ]
[ 219 ]
1
[]
[]
0
true
Family
Atracotoxin
Atracotoxin
Atracotoxin
2
IPR020203
20,203
Membrane protein YneK
YneK
Family
1,464
false
false
This is a group of uncharacterised membrane bacterial proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF11084" ]
[ "DUF2621" ]
[ 1464 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Eukaryota", "hydrothermal vent metagenome" ]
[ 1460, 2, 2 ]
3
[]
[]
0
true
Family
Membrane protein YneK
Membrane protein YneK
YneK
4
IPR020204
20,204
Uncharacterised protein family, YxaJ
Uncharacterised_YxaJ
Family
158
false
false
This entry represents a group of uncharacterised transmembrane proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17369" ]
[ "DUF5391" ]
[ 158 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota" ]
[ 158 ]
1
[]
[]
0
true
Family
Uncharacterised protein family, YxaJ
Uncharacterised protein family, YxaJ
Uncharacterised_YxaJ
5
IPR020205
20,205
Uncharacterised protein family, YwnF, transmembrane
Uncharacterised_YwnF_TM
Family
236
false
false
This entry represents a group of uncharacterised transmembrane proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17370" ]
[ "DUF5392" ]
[ 236 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacilli" ]
[ 236 ]
1
[]
[]
0
true
Family
Uncharacterised protein family, YwnF, transmembrane
Uncharacterised protein family, YwnF, transmembrane
Uncharacterised_YwnF_TM
1
IPR020206
20,206
Uncharacterised protein family, VP2110
Uncharacterised_VP2110
Family
1,458
false
false
This entry represents a group of uncharacterised proteins which includes Uncharacterized protein VP2110.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10952" ]
[ "DUF2753" ]
[ 1458 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus thuringiensis phage MZTP02", "Bacteria", "Eukaryota", "marine sediment metagenome" ]
[ 1, 1442, 13, 2 ]
4
[]
[]
0
true
Family
Uncharacterised protein family, VP2110
Uncharacterised protein family, VP2110
Uncharacterised_VP2110
8
IPR020207
20,207
Metastasis-suppressor KiSS-1
Metastasis-suppressor_KiSS-1
Family
304
false
false
Kisspeptin (KiSS-1) is a metastasis suppressor protein found in malignant melanomas and in some breast cancers [ ]. KiSS-1 may regulate events downstream of cell-matrix adhesion, which could involve cytoskeletal reorganisation. KiSS-1 generates a C-terminally amidated peptide, metastin, which functions as the endogenou...
[]
[]
[]
0
[ "PFAM", "PANTHER" ]
[ "PF15152", "PTHR16955" ]
[ "Kisspeptin", "" ]
[ 257, 284 ]
2
[ "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME", "REACTOME" ]
[ "R-HSA-375276", "R-HSA-416476", "R-MMU-375276", "R-MMU-416476", "R-RNO-375276", "R-RNO-416476" ]
[ "REACTOME:R-HSA-375276", "REACTOME:R-HSA-416476", "REACTOME:R-MMU-375276", "REACTOME:R-MMU-416476", "REACTOME:R-RNO-375276", "REACTOME:R-RNO-416476" ]
6
[ "8xgs" ]
1
[ "PUB00045954", "PUB00045955", "PUB00045956", "PUB00046119" ]
[ "18583061", "16288036", "17351756", "15684075" ]
[ "The kisspeptin (KiSS-1)/GPR54 system in cancer biology.", "Kisspeptin-10-induced signaling of GPR54 negatively regulates chemotactic responses mediated by CXCR4: a potential mechanism for the metastasis suppressor activity of kisspeptins.", "Kisspeptins and the placenta: regulation of trophoblast invasion.", ...
[ 2008, 2005, 2007, 2005 ]
4
[]
[]
0
0
null
[ "Gnathostomata" ]
[ 304 ]
1
[ "Danio rerio", "Homo sapiens", "Mus musculus", "Rattus norvegicus" ]
[ 1, 1, 3, 3 ]
4
true
Family
Metastasis-suppressor KiSS-1
Metastasis-suppressor KiSS-1
Metastasis-suppressor_KiSS-1
9
IPR020208
20,208
Protein of unknown function DUF2712
DUF2712
Family
394
false
false
This entry represents a group of uncharacterised proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10916" ]
[ "DUF2712" ]
[ 394 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillati", "Metamonada", "human gut metagenome" ]
[ 387, 6, 1 ]
3
[]
[]
0
true
Family
Protein of unknown function DUF2712
Protein of unknown function DUF2712
DUF2712
1
IPR020209
20,209
Cas6b, C-terminal domain
Cas6b_C
Domain
386
false
false
Clustered, regularly interspaced, short palindromic repeat (CRISPR) loci play a pivotal role in the prokaryotic host defence system against invading genetic materials. The CRISPR loci are transcribed to produce CRISPR RNAs (crRNAs), which form interference complexes with CRISPR-associated (Cas) proteins to target the i...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17262" ]
[ "Cas6b_C" ]
[ 386 ]
1
[]
[]
[]
0
[ "4z7k", "4z7l" ]
2
[ "PUB00085160", "PUB00085375", "PUB00085376" ]
[ "28238733", "25451598", "26996962" ]
[ "Fragmentation of the CRISPR-Cas Type I-B signature protein Cas8b.", "Crystal structure of the Csm3-Csm4 subcomplex in the type III-A CRISPR-Cas interference complex.", "A Non-Stem-Loop CRISPR RNA Is Processed by Dual Binding Cas6." ]
[ 2017, 2015, 2016 ]
3
[]
[]
0
0
null
[ "Archaea", "Bacteria", "metagenomes" ]
[ 130, 229, 27 ]
3
[]
[]
0
true
Domain
Cas6b, C-terminal domain
Cas6b, C-terminal domain
Cas6b_C
9
IPR020210
20,210
Uncharacterised protein family, YpbF, transmembrane
Uncharacterised_YpbF_TM
Family
536
false
false
This entry represents a group of uncharacterised transmembrane proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10864" ]
[ "DUF2663" ]
[ 536 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillati" ]
[ 536 ]
1
[]
[]
0
true
Family
Uncharacterised protein family, YpbF, transmembrane
Uncharacterised protein family, YpbF, transmembrane
Uncharacterised_YpbF_TM
1
IPR020213
20,213
Toxin coregulated pilus biosynthesis protein TcpS
Toxin-coreg_pilus_synth_TcpS
Family
13
false
false
Toxin coregulated pilus biosynthesis protein S (TcpS) is part of an operon associated with biosynthesis of the toxin coregulated pilus (TCP) of Vibrio cholerae [ ]. TCP is essential for successful colonisation of the bacteria in the small intestine. The genes tcpR, tcpD, tcpS, tcpT, tcpE and tcpF are organised to permi...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17456" ]
[ "TcpS" ]
[ 13 ]
1
[]
[]
[]
0
[]
0
[ "PUB00045958", "PUB00045959" ]
[ "18462070", "8097178" ]
[ "Distribution of genes for virulence and ecological fitness among diverse Vibrio cholerae population in a cholera endemic area: tracking the evolution of pathogenic strains.", "Genetic organization and sequence of the promoter-distal region of the tcp gene cluster of Vibrio cholerae." ]
[ 2008, 1993 ]
2
[]
[]
0
0
null
[ "Vibrionaceae" ]
[ 13 ]
1
[]
[]
0
true
Family
Toxin coregulated pilus biosynthesis protein TcpS
Toxin coregulated pilus biosynthesis protein TcpS
Toxin-coreg_pilus_synth_TcpS
3
IPR020214
20,214
Cytomegalovirus UL124
Cytomega_UL124
Family
49
false
false
This is a family of unknown function found in cytomegalovirus. Family member UL124 is a predicted membrane glycoprotein with one predicted trans-membrane region [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF17609" ]
[ "HCMV_UL124" ]
[ 49 ]
1
[ "REACTOME" ]
[ "R-HSA-9609690" ]
[ "REACTOME:R-HSA-9609690" ]
1
[]
0
[ "PUB00085213" ]
[ "22109557" ]
[ "High-resolution human cytomegalovirus transcriptome." ]
[ 2011 ]
1
[]
[]
0
0
null
[ "Cytomegalovirus" ]
[ 49 ]
1
[]
[]
0
true
Family
Cytomegalovirus UL124
Cytomegalovirus UL124
Cytomega_UL124
6
IPR020215
20,215
EbsA-like
EbsA-like
Family
1,019
false
false
The pore-forming protein EbsA is one of three proteins (EbsA, EbsB, and EbsC) that affects the expression of a chromosomally encoded receptor, named binding substance (BS). In Enterococcus faecalis (Streptococcus faecalis), transfer of the conjugative plasmid pCF10 involves production of a plasmid-encoded aggregation s...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17255" ]
[ "EbsA" ]
[ 1019 ]
1
[]
[]
[]
0
[]
0
[ "PUB00017205" ]
[ "8226689" ]
[ "Cloning and molecular analysis of genes affecting expression of binding substance, the recipient-encoded receptor(s) mediating mating aggregate formation in Enterococcus faecalis." ]
[ 1993 ]
1
[]
[]
0
0
null
[ "Bacteria", "human gut metagenome" ]
[ 1018, 1 ]
2
[]
[]
0
true
Family
EbsA-like
EbsA-like
EbsA-like
1
IPR020216
20,216
Uncharacterised protein family, YncE
Uncharacterised_YncE
Family
396
false
false
This entry represents a group of uncharacterised proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10903" ]
[ "DUF2691" ]
[ 396 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillati", "bioreactor metagenome" ]
[ 394, 2 ]
2
[]
[]
0
true
Family
Uncharacterised protein family, YncE
Uncharacterised protein family, YncE
Uncharacterised_YncE
5
IPR020221
20,221
Protein of unknown function DUF5505
DUF5505
Family
37
false
false
This is a family of unknown function found in Alphabaculovirus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17610" ]
[ "DUF5505" ]
[ 37 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Alphabaculovirus" ]
[ 37 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5505
Protein of unknown function DUF5505
DUF5505
3
IPR020226
20,226
Avian adenovirus Orf17
Avian_adenovirus_Orf17
Family
47
false
false
This entry represents a group of uncharacterised proteins found in various avian (fowl) adenoviruses [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF17611" ]
[ "DUF5506" ]
[ 47 ]
1
[]
[]
[]
0
[]
0
[ "PUB00045963" ]
[ "19184805" ]
[ "Detection and differentiation of avian adenoviruses: a review." ]
[ 2000 ]
1
[]
[]
0
0
null
[ "Aviadenovirus" ]
[ 47 ]
1
[]
[]
0
true
Family
Avian adenovirus Orf17
Avian adenovirus Orf17
Avian_adenovirus_Orf17
3
IPR020227
20,227
YpjCB-like, N-terminal domain
DUF5507
Domain
87
false
false
This entry represents the N-terminal predicted domain is from the YpjCB family protein found in Enterobacteriaceae. It includes uncharacterised protein YpjC in which this domain is standalone.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17612" ]
[ "DUF5507" ]
[ 87 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria" ]
[ 87 ]
1
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Domain
YpjCB-like, N-terminal domain
YpjCB-like, N-terminal domain
DUF5507
4
IPR020230
20,230
Transcription regulator MotB
Tscrpt_reg_MotB
Family
404
false
false
This entry represents the transcription regulatory protein MotB, which is found in various Enterobacteria phages [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF17613" ]
[ "motB" ]
[ 404 ]
1
[]
[]
[]
0
[]
0
[ "PUB00085212" ]
[ "21507986" ]
[ "T4-Like genome organization of the Escherichia coli O157:H7 lytic phage AR1." ]
[ 2011 ]
1
[]
[]
0
0
null
[ "Salmonella dublin", "Viruses" ]
[ 1, 403 ]
2
[]
[]
0
true
Family
Transcription regulator MotB
Transcription regulator MotB
Tscrpt_reg_MotB
8
IPR020231
20,231
Uncharacterised protein family, YfgI
Uncharacterised_YfgI
Family
440
false
false
This entry represents a group of uncharacterised proteins.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17358" ]
[ "DUF5384" ]
[ 440 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Pseudomonadati", "Punavirus", "human gut metagenome" ]
[ 434, 5, 1 ]
3
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Uncharacterised protein family, YfgI
Uncharacterised protein family, YfgI
Uncharacterised_YfgI
1
IPR020233
20,233
GSE/EGO complex subunit Slm4
Slm4
Family
114
false
false
Budding yeast Slm4 is a component of both the GSE and the EGO complexes. The GSE (GAP1 Sorting in the Endosomes) complex is a GTPase complex required for intracellular sorting of Gap1 out of the endosome, which is required for the eventual delivery of GAP1 to the plasma membrane [ ]. The GSE complex is composed of two ...
[ "GO:0007165", "GO:0071986" ]
[ "signal transduction", "Ragulator complex" ]
[ "biological_process", "cellular_component" ]
2
[ "PFAM" ]
[ "PF16818" ]
[ "SLM4" ]
[ 114 ]
1
[]
[]
[]
0
[ "3lgo", "4ftx", "4fuw", "4xpm", "6jwp", "9h4q", "9h5k" ]
7
[ "PUB00045964", "PUB00045965" ]
[ "16732272", "15989961" ]
[ "A conserved GTPase-containing complex is required for intracellular sorting of the general amino-acid permease in yeast.", "The TOR and EGO protein complexes orchestrate microautophagy in yeast." ]
[ 2006, 2005 ]
2
[]
[]
0
0
null
[ "Saccharomycotina" ]
[ 114 ]
1
[ "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]
[ 1 ]
1
true
Family
GSE/EGO complex subunit Slm4
GSE/EGO complex subunit Slm4
Slm4
9
IPR020234
20,234
Mite allergen, group-7
Mite_allergen_group-7
Family
1,844
false
false
This entry contains proteins that cause an allergic reaction in humans. Common symptoms of mite allergy are bronchial asthma, allergic rhinitis and conjunctivitis [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF16984" ]
[ "Grp7_allergen" ]
[ 1844 ]
1
[]
[]
[]
0
[ "3h4z", "3uv1", "9hae", "9haf" ]
4
[ "PUB00075922" ]
[ "22970319" ]
[ "Crystal structure of Der f 7, a dust mite allergen from Dermatophagoides farinae." ]
[ 2012 ]
1
[]
[]
0
0
null
[ "Eukaryota" ]
[ 1844 ]
1
[ "Drosophila melanogaster" ]
[ 3 ]
1
true
Family
Mite allergen, group-7
Mite allergen, group-7
Mite_allergen_group-7
7
IPR020236
20,236
Uncharacterised protein family YebF
Uncharacterised_YebF
Family
491
false
false
This entry represents a group of uncharacterised proteins. Though their function is not known, proteins in this family have been show to be secreted [ ].
[]
[]
[]
0
[ "HAMAP" ]
[ "MF_01435" ]
[ "YebF" ]
[ 491 ]
1
[]
[]
[]
0
[]
0
[ "PUB00053960" ]
[ "16369539" ]
[ "Extracellular accumulation of recombinant proteins fused to the carrier protein YebF in Escherichia coli." ]
[ 2006 ]
1
[ "IPR025603" ]
[]
1
0
1
[ "Bacteria" ]
[ 491 ]
1
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Uncharacterised protein family YebF
Uncharacterised protein family YebF
Uncharacterised_YebF
5
IPR020239
20,239
Protein of unknown function DUF5511
DUF5511
Family
23
false
false
This is a family of unknown function found in Bacillus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17630" ]
[ "DUF5511" ]
[ 23 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota" ]
[ 23 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5511
Protein of unknown function DUF5511
DUF5511
9
IPR020240
20,240
Uncharacterised protein family UPF0412, YaaI
UPF0412_YaaI
Family
1,128
false
false
This entry represents proteins mainly found in gammaproteobacteria that have no known function.
[]
[]
[]
0
[ "HAMAP", "NCBIFAM", "PFAM" ]
[ "MF_01372", "NF007541", "PF10807" ]
[ "UPF0412", "PRK10154.1", "DUF2541" ]
[ 586, 627, 1128 ]
3
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Protostomia", "metagenomes" ]
[ 1122, 2, 4 ]
3
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Uncharacterised protein family UPF0412, YaaI
Uncharacterised protein family UPF0412, YaaI
UPF0412_YaaI
7
IPR020241
20,241
Ribonuclease P/MRP subunit Pop7, fungi
RNase_P/MRP_Pop7_fungi
Family
1,136
false
false
Subunit Pop7 is a component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. It is also a component of RNase MRP, which cleaves pre-rRNA sequences [ , ]. In yeasts, RNase P consists of an RNA moiety and at least 9 protein subunits including Pop1, Pop3, Pop4, Pop5, Pop...
[ "GO:0001682", "GO:0006396", "GO:0000172", "GO:0005655" ]
[ "tRNA 5'-leader removal", "RNA processing", "ribonuclease MRP complex", "nucleolar ribonuclease P complex" ]
[ "biological_process", "biological_process", "cellular_component", "cellular_component" ]
4
[ "PANTHER" ]
[ "PTHR28256" ]
[ "" ]
[ 1136 ]
1
[]
[]
[]
0
[ "3iab", "6agb", "6ah3", "6w6v", "7c79", "7c7a" ]
6
[ "PUB00045988", "PUB00046121" ]
[ "9620854", "9618478" ]
[ "Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.", "Rpp2, an essential protein subunit of nuclear RNase P, is required for processing of precursor tRNAs and 35S precursor rRNA in Saccharomyces cerevisiae." ]
[ 1998, 1998 ]
2
[ "IPR014612" ]
[]
1
0
1
[ "Opisthokonta" ]
[ 1136 ]
1
[ "Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)", "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]
[ 1, 1 ]
2
true
Family
Ribonuclease P/MRP subunit Pop7, fungi
Ribonuclease P/MRP subunit Pop7, fungi
RNase_P/MRP_Pop7_fungi
3
IPR020242
20,242
Conotoxin I2
Conotoxin_I2
Family
158
false
false
Members of this family display a XI cysteine pattern (C-C-CC-CC-C-C) and belong to the I2- superfamily conotoxins. Family members such as Kappa-conotoxin ViTx ( ) and Kappa-conotoxin SrXIA ( ) inhibit voltage gated potassium channels (Kv) [ ]. Cone snail toxins, conotoxins, are small peptides with disulphide connectivi...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17557" ]
[ "Conotoxin_I2" ]
[ 158 ]
1
[]
[]
[]
0
[ "9nvh" ]
1
[ "PUB00016617", "PUB00016620", "PUB00016662", "PUB00085232" ]
[ "11478951", "15225557", "10903392", "25522317" ]
[ "Cone venom--from accidental stings to deliberate injection.", "Toxins in anti-nociception and anti-inflammation.", "Conotoxins - new vistas for peptide therapeutics.", "Conotoxin gene superfamilies." ]
[ 2001, 2004, 2000, 2014 ]
4
[]
[]
0
0
null
[ "Conoidea" ]
[ 158 ]
1
[]
[]
0
true
Family
Conotoxin I2
Conotoxin I2
Conotoxin_I2
2
IPR020244
20,244
Rotavirus B, non-structural protein 5
Rotavirus_B_NSP5
Family
110
false
false
This entry represents non-structural protein 5 from rotaviruses. It is involved in genome replication, playing a crucial role in the formation of virus factories (viroplasms) which are large inclusions in the cytoplasm where core-like replication intermediates are assembled and RNA replication takes place. It forms a h...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17580" ]
[ "GBR_NSP5" ]
[ 110 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Sedoreoviridae" ]
[ 110 ]
1
[]
[]
0
true
Family
Rotavirus B, non-structural protein 5
Rotavirus B, non-structural protein 5
Rotavirus_B_NSP5
2
IPR020246
20,246
Uncharacterised protein family SCO3924
Uncharacterised_SCO3924
Family
878
false
false
This entry contains proteins that are confined to Streptomyces species. The protein family, which includes SCO3924, is currently uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17260" ]
[ "DUF5326" ]
[ 878 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Actinomycetes" ]
[ 878 ]
1
[]
[]
0
true
Family
Uncharacterised protein family SCO3924
Uncharacterised protein family SCO3924
Uncharacterised_SCO3924
2
IPR020248
20,248
MobB-Gp55
MobB-Gp55
Family
222
false
false
This entry represents Uncharacterized 8.5 kDa protein in mobB-Gp55 intergenic region and other uncharacterised proteins found in a number of T4-like bacteriophages.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17595" ]
[ "DUF5491" ]
[ 222 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Viruses" ]
[ 222 ]
1
[]
[]
0
true
Family
MobB-Gp55
MobB-Gp55
MobB-Gp55
3
IPR020249
20,249
Protein of unknown function DUF5492
DUF5492
Family
12
false
false
This is a family of unknown function found in Alphabaculovirus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17596" ]
[ "DUF5492" ]
[ 12 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Alphabaculovirus" ]
[ 12 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5492
Protein of unknown function DUF5492
DUF5492
1
IPR020250
20,250
Uncharacterised protein family, plasmid pXO2-72
Plasmid_pXO2-72
Family
99
false
false
This is a family of unknown function mostly found in Bacilli.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17443" ]
[ "pXO2-72" ]
[ 99 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillales" ]
[ 99 ]
1
[]
[]
0
true
Family
Uncharacterised protein family, plasmid pXO2-72
Uncharacterised protein family, plasmid pXO2-72
Plasmid_pXO2-72
2
IPR020251
20,251
Uncharacterised protein family, YmjA
Uncharacterised_YmjA
Family
491
false
false
This entry contains proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10820" ]
[ "DUF2543" ]
[ 491 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Opisthokonta", "human gut metagenome" ]
[ 488, 2, 1 ]
3
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Uncharacterised protein family, YmjA
Uncharacterised protein family, YmjA
Uncharacterised_YmjA
4
IPR020253
20,253
Torovirus, nucleocapsid protein
Torovirus_nucleocapsid
Family
71
false
false
This entry represents the nucleocapsid protein from bovine, porcine and equine toroviruses. It is the major structural component of virions associating with the virion genomic RNA.
[]
[]
[]
0
[ "PFAM" ]
[ "PF11030" ]
[ "Nucleocapsid-N" ]
[ 71 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Eukaryota", "Torovirus" ]
[ 7, 64 ]
2
[]
[]
0
true
Family
Torovirus, nucleocapsid protein
Torovirus, nucleocapsid protein
Torovirus_nucleocapsid
8
IPR020255
20,255
Minor curli fiber component A
CsgA
Family
317
false
false
Curli are extracellular functional amyloids that are assembled by enteric bacteria during biofilm formation and host colonization. The csg (curli specific gene) operon encodes major structural and accessory proteins that are required for curli production. The csgBAC operon encodes the major and minor curli fibre compon...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17334" ]
[ "CsgA" ]
[ 317 ]
1
[]
[]
[]
0
[]
0
[ "PUB00091004", "PUB00091005" ]
[ "25620560", "21877724" ]
[ "The bacterial curli system possesses a potent and selective inhibitor of amyloid formation.", "Fibrillation of the major curli subunit CsgA under a wide range of conditions implies a robust design of aggregation." ]
[ 2015, 2011 ]
2
[]
[]
0
0
null
[ "Bacteria" ]
[ 317 ]
1
[]
[]
0
true
Family
Minor curli fiber component A
Minor curli fiber component A
CsgA
7
IPR020256
20,256
Spore coat protein CotJA
Spore_coat_CotJA
Family
2,199
false
false
The open reading frame cotJA is part of the cotJ operon, which encodes spore coat proteins. Interaction of CotJA with CotJC is required for the assembly of both CotJA and CotJC into the spore coat [ ].
[]
[]
[]
0
[ "PFAM" ]
[ "PF11007" ]
[ "CotJA" ]
[ 2199 ]
1
[]
[]
[]
0
[]
0
[ "PUB00055560" ]
[ "9364920" ]
[ "Assembly and interactions of cotJ-encoded proteins, constituents of the inner layers of the Bacillus subtilis spore coat." ]
[ 1997 ]
1
[]
[]
0
0
null
[ "Bacteria", "metagenomes" ]
[ 2185, 14 ]
2
[]
[]
0
true
Family
Spore coat protein CotJA
Spore coat protein CotJA
Spore_coat_CotJA
9
IPR020257
20,257
Protein of unknown function DUF5512
DUF5512
Family
24
false
false
This is a family of unknown function found in Bacillus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17631" ]
[ "DUF5512" ]
[ 24 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillus cereus group" ]
[ 24 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5512
Protein of unknown function DUF5512
DUF5512
2
IPR020258
20,258
Uncharacterised protein family YbeF
Uncharacterised_YbeF
Family
750
false
false
This entry contains transmembrane proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10852" ]
[ "DUF2651" ]
[ 750 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "Methanocorpusculaceae", "Siphoviridae sp. ctES717", "metagenomes" ]
[ 740, 4, 1, 5 ]
4
[]
[]
0
true
Family
Uncharacterised protein family YbeF
Uncharacterised protein family YbeF
Uncharacterised_YbeF
7
IPR020260
20,260
Uncharacterised protein family YueH
Uncharacterised_YueH
Family
423
false
false
This entry contains proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF14166" ]
[ "YueH" ]
[ 423 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "human gut metagenome" ]
[ 422, 1 ]
2
[]
[]
0
true
Family
Uncharacterised protein family YueH
Uncharacterised protein family YueH
Uncharacterised_YueH
7
IPR020261
20,261
Protein of unknown function DUF5493
DUF5493
Family
19
false
false
This is a family of unknown function mainly found in Sulfolobus viruses.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17597" ]
[ "DUF5493" ]
[ 19 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Fuselloviridae", "Sulfolobaceae" ]
[ 9, 10 ]
2
[]
[]
0
true
Family
Protein of unknown function DUF5493
Protein of unknown function DUF5493
DUF5493
9
IPR020262
20,262
Uncharacterised protein family YecJ
Uncharacterised_YecJ
Family
542
false
false
This entry contains proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10964" ]
[ "DUF2766" ]
[ 542 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Gammaproteobacteria", "Lasius niger" ]
[ 541, 1 ]
2
[ "Escherichia coli (strain K12)" ]
[ 1 ]
1
true
Family
Uncharacterised protein family YecJ
Uncharacterised protein family YecJ
Uncharacterised_YecJ
8
IPR020265
20,265
Protein of unknown function DUF5513
DUF5513
Family
26
false
false
This is a family of unknown function found in Bacillus.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17632" ]
[ "DUF5513" ]
[ 26 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota" ]
[ 26 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF5513
Protein of unknown function DUF5513
DUF5513
9
IPR020266
20,266
Mitochondrial import receptor subunit Tom6
Tom6
Family
355
false
false
Translocation of preproteins across the mitochondrial outer membrane is mediated by the translocase of the outer mitochondrial membrane (TOM) complex. Tom6 and Tom7, two small subunits of the TOM core are in direct contact with the major component of the pore, Tom40. In addition, Tom6 interacts with Tom22 in a manner t...
[ "GO:0030150", "GO:0005742" ]
[ "protein import into mitochondrial matrix", "mitochondrial outer membrane translocase complex" ]
[ "biological_process", "cellular_component" ]
2
[ "PFAM" ]
[ "PF17112" ]
[ "Tom6" ]
[ 355 ]
1
[]
[]
[]
0
[ "6jnf", "6ucu", "6ucv", "7e4i", "8hco", "8w5j", "8w5k", "8xkw", "8xkx", "8xky", "9j99" ]
11
[ "PUB00045970", "PUB00075722", "PUB00075723" ]
[ "11278536", "21765393", "24781695" ]
[ "Assembly of Tom6 and Tom7 into the TOM core complex of Neurospora crassa.", "Lateral release of proteins from the TOM complex into the outer membrane of mitochondria.", "The presequence pathway is involved in protein sorting to the mitochondrial outer membrane." ]
[ 2001, 2011, 2014 ]
3
[]
[]
0
0
null
[ "Bacillota", "Eukaryota" ]
[ 4, 351 ]
2
[ "Saccharomyces cerevisiae (strain ATCC 204508 / S288c)" ]
[ 1 ]
1
true
Family
Mitochondrial import receptor subunit Tom6
Mitochondrial import receptor subunit Tom6
Tom6
4
IPR020269
20,269
Releasin protein, Bacteriophage Mu
Phage_Mu_Releasin
Family
858
false
false
This family includes Releasin protein from phage Mu, also known as Gp25, which facilitates the release of the SAR-endolysin [ ]. The uncharacterised protein HI1498 from Haemophilus influenzae is also included in this entry.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10805" ]
[ "DUF2730" ]
[ 858 ]
1
[]
[]
[]
0
[]
0
[ "PUB00101887" ]
[ "35471081" ]
[ "Endolysin Regulation in Phage Mu Lysis." ]
[ 2022 ]
1
[]
[]
0
0
null
[ "Bacteria", "Caudoviricetes", "Eukaryota", "Thermoprotei", "metagenomes" ]
[ 832, 13, 2, 3, 8 ]
5
[]
[]
0
true
Family
Releasin protein, Bacteriophage Mu
Releasin protein, Bacteriophage Mu
Phage_Mu_Releasin
5
IPR020270
20,270
Uncharacterised protein family, plasmid pXO2-34
Plasmid_pXO2-34
Family
66
false
false
This entry represents various hypothetical proteins from bacteria, and is confined to Bacillus. The protein Y6533 from Bacillus anthracis is encoded on plasmid pXO2 and is currently uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17362" ]
[ "pXO2-34" ]
[ 66 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota" ]
[ 66 ]
1
[]
[]
0
true
Family
Uncharacterised protein family, plasmid pXO2-34
Uncharacterised protein family, plasmid pXO2-34
Plasmid_pXO2-34
9
IPR020271
20,271
Uncharacterised protein family, MJ1172
Uncharacterised_MJ1172
Family
854
false
false
This entry includes the putative antitoxin RelB4 from Methanocaldococcus jannaschii (UniProt: Q58572). Most of the members in this entry are uncharacterised.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10884" ]
[ "DUF2683" ]
[ 854 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Archaea", "Bacteria", "Daphnia magna", "ecological metagenomes" ]
[ 65, 783, 1, 5 ]
4
[]
[]
0
true
Family
Uncharacterised protein family, MJ1172
Uncharacterised protein family, MJ1172
Uncharacterised_MJ1172
9
IPR020272
20,272
Uncharacterized protein C-84-like
C-84-like
Family
6
false
false
This entry a family of uncharacterised protein found mainly in Sulfolobus viruses.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17598" ]
[ "DUF5494" ]
[ 6 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Fuselloviridae", "Sulfolobaceae" ]
[ 4, 2 ]
2
[]
[]
0
true
Family
Uncharacterized protein C-84-like
Uncharacterized protein C-84-like
C-84-like
8
IPR020274
20,274
Uncharacterised protein family HI1496
Uncharacterised_HI1496
Family
119
false
false
This entry contains membrane proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF10883" ]
[ "DUF2681" ]
[ 119 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacteria", "unclassified Caudoviricetes" ]
[ 115, 4 ]
2
[]
[]
0
true
Family
Uncharacterised protein family HI1496
Uncharacterised protein family HI1496
Uncharacterised_HI1496
5
IPR020275
20,275
Protein of unknown function DUF5592
DUF5592
Family
588
false
false
This is a family of unknown function found in bacteria, including Uncharacterized protein pXO2-11/BXB0010/GBAA_pXO2_0010 (pXO2-11) [ ]. Family members contain two predicted trans-membrane regions.
[]
[]
[]
0
[ "PFAM" ]
[ "PF17332" ]
[ "DUF5592" ]
[ 588 ]
1
[]
[]
[]
0
[]
0
[ "PUB00162456" ]
[ "10475962" ]
[ "Sequence, assembly and analysis of pX01 and pX02." ]
[ 1999 ]
1
[]
[]
0
0
null
[ "Bacteria", "Methanobrevibacter smithii", "metagenomes" ]
[ 585, 1, 2 ]
3
[]
[]
0
true
Family
Protein of unknown function DUF5592
Protein of unknown function DUF5592
DUF5592
7
IPR020277
20,277
Protein of unknown function DUF2624
DUF2624
Family
796
false
false
This entry contains proteins with no known function.
[]
[]
[]
0
[ "PFAM" ]
[ "PF11116" ]
[ "DUF2624" ]
[ 796 ]
1
[]
[]
[]
0
[]
0
[]
[]
[]
[]
0
[]
[]
0
0
null
[ "Bacillota" ]
[ 796 ]
1
[]
[]
0
true
Family
Protein of unknown function DUF2624
Protein of unknown function DUF2624
DUF2624
1
IPR020278
20,278
Small protein YqaH-like
YqaH-like
Family
80
false
false
This entry represents Small protein YqaH from Bacillus subtilis and similar sequences from Bacillales. YqaH binds to and counteracts DnaA replication initiation activity. Its overexpression decreases the number of replication initiation events. It also antagonizes DnaA's transcriptional regulation activity [ ]. This pr...
[]
[]
[]
0
[ "PFAM" ]
[ "PF17448" ]
[ "YqaH" ]
[ 80 ]
1
[]
[]
[]
0
[]
0
[ "PUB00056587", "PUB00056588", "PUB00160370" ]
[ "20889742", "12060778", "36748575" ]
[ "Repression of sigK intervening (skin) element gene expression by the CI-like protein SknR and effect of SknR depletion on growth of Bacillus subtilis cells.", "An expanded view of bacterial DNA replication.", "Prophage-encoded small protein YqaH counteracts the activities of the replication initiator DnaA in <...
[ 2010, 2002, 2022 ]
3
[]
[]
0
0
null
[ "Bacillaceae", "Caudoviricetes" ]
[ 78, 2 ]
2
[]
[]
0
true
Family
Small protein YqaH-like
Small protein YqaH-like
YqaH-like
7