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Carnitine-acylcarnitine translocase | Carnitine-acylcarnitine translocase (CACT) is responsible for passive transport of carnitine and carnitine-fatty acid complexes and across the inner mitochondrial membrane as part of the carnitine shuttle system. |
Antaryamin | The Antaryamin, in terms of Hindu philosophy, is related to the "inner-self", the "inner-controller" or the "inner-guidance" that exists in a person and itself manifests on an intuitive way to the one manifesting it. It recalls a teacher or a guru that resides within and once it is manifested - for a higher context of knowledge guidance - usually after one summons or prays for it, the Antaryamin comes to help. In some cases, the Antaryamin is asked to be manifested in order to resolve non-intellectual issues, also performing miracles to the one asking. |
Vital signs | Vital signs (also known as vitals) are a group of the four to six most crucial medical signs that indicate the status of the body's vital (life-sustaining) functions. These measurements are taken to help assess the general physical health of a person, give clues to possible diseases, and show progress toward recovery. The normal ranges for a person's vital signs vary with age, weight, sex, and overall health.There are four primary vital signs: body temperature, blood pressure, pulse (heart rate), and breathing rate (respiratory rate), often notated as BT, BP, HR, and RR. However, depending on the clinical setting, the vital signs may include other measurements called the "fifth vital sign" or "sixth vital sign". Vital signs are recorded using the LOINC internationally accepted standard coding system.Early warning scores have been proposed that combine the individual values of vital signs into a single score. This was done in recognition that deteriorating vital signs often precede cardiac arrest and/or admission to the intensive care unit. Used appropriately, a rapid response team can assess and treat a deteriorating patient and prevent adverse outcomes. |
Electromagnetic pulse | An electromagnetic pulse (EMP), also referred to as a transient electromagnetic disturbance (TED), is a brief burst of electromagnetic energy. The origin of an EMP can be natural or artificial, and can occur as an electromagnetic field, as an electric field, as a magnetic field, or as a conducted electric current. The electromagnetic interference caused by an EMP can disrupt communications and damage electronic equipment. An EMP such as a lightning strike can physically damage objects such as buildings and aircraft. The management of EMP effects is a branch of electromagnetic compatibility (EMC) engineering. |
Carbocisteine | Carbocisteine, also called carbocysteine, is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily. Carbocisteine should not be used with antitussives (cough suppressants) or medicines that dry up bronchial secretions.
It was first described in 1951 and came into medical use in 1960. Carbocisteine is produced by alkylation of cysteine with chloroacetic acid. |
Olive oil extraction | Olive oil extraction is the process of extracting the olive oil present in olive drupes. Olive oil is produced in the mesocarp cells, and stored in a particular type of vacuole called a lipo vacuole, i.e., every cell contains a tiny olive oil droplet. Olive oil extraction is the process of separating the oil from the other fruit contents (vegetative extract liquid and solid material). It is possible to attain this separation by physical means alone, i.e., oil and water do not mix, so they are relatively easy to separate. This contrasts with other oils that are extracted with chemical solvents, generally hexane. The first operation when extracting olive oil is washing the olives, to reduce the presence of contaminants, especially soil which can create a particular flavor effect called "soil taste". |
Pixilation | Pixilation is a stop motion technique in which live actors are used as a frame-by-frame subject in an animated film, by repeatedly posing while one or more frame is taken and changing pose slightly before the next frame or frames. The actor becomes a kind of living stop-motion puppet. This technique is often used as a way to blend live actors with animated ones in a movie, such as in The Secret Adventures of Tom Thumb by the Bolex Brothers. |
Oblivious data structure | In computer science, an oblivious data structure is a data structure that gives no information about the sequence or pattern of the operations that have been applied except for the final result of the operations.In most conditions, even if the data is encrypted, the access pattern can be achieved, and this pattern can leak some important information such as encryption keys. And in the outsourcing of cloud data, this leakage of access pattern is still very serious. An access pattern is a specification of an access mode for every attribute of a relation schema. For example, the sequences of user read or write the data in the cloud are access patterns. |
Dual-mode mobile | Dual-mode mobiles refer to mobile phones that are compatible with more than one form of data transmission or network. |
Market overhang | Market overhang is a term derived from the physical world meaning things that stick out or hang over another thing. Often from the viewpoint of standing beneath an 'overhang' there is shade provided by a protrusion from the adjacent vertical domain, such as a tree or building. |
Myelin basic protein | Myelin basic protein (MBP) is a protein believed to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. MBP maintains the correct structure of myelin, interacting with the lipids in the myelin membrane.MBP was initially sequenced in 1971 after isolation from bovine myelin membranes. MBP knockout mice called shiverer mice were subsequently developed and characterized in the early 1980s. Shiverer mice exhibit decreased amounts of CNS myelination and a progressive disorder characterized by tremors, seizures, and early death. The human gene for MBP is on chromosome 18; the protein localizes to the CNS and to various cells of the hematopoietic lineage. |
Web Application Description Language | The Web Application Description Language (WADL) is a machine-readable XML description of HTTP-based web services. WADL models the resources provided by a service and the relationships between them. WADL is intended to simplify the reuse of web services that are based on the existing HTTP architecture of the Web. It is platform and language independent and aims to promote reuse of applications beyond the basic use in a web browser. |
Wall stud | A wall stud is a vertical repetitive framing member in a building's wall of smaller cross section than a post. It is a fundamental element in frame building. |
Olympus SP-500 Ultra Zoom | The Olympus SP 500 Ultra Zoom is a 6.0-megapixel compact ultra-zoom digital camera introduced by Olympus Corporation in 2005.
It features a 2.5" LCD display, a 10x zoom lens, and 5x digital zoom in a compact lightweight body. It is designed to satisfy the needs of both hobbyist photographers who desire full control over exposure settings and those that need only point and shoot simplicity. |
Gene Pool (software) | Gene Pool is an artificial life simulation created by Jeffrey Ventrella in 1997. It features physics-based 2D proto-swimming creatures (swimbots) that compete for mates and food. |
Downdraft table | Downdraft tables or downdraught benches are workbenches with built-in ventilation to capture dust, smoke, and fumes and draw them away from the operator and the material being worked on. They typically consist of a perforated surface whose underside is connected to a ventilation or dust collection system, to draw material through the holes and away from the work. |
HP 9000 | HP 9000 is a line of workstation and server computer systems produced by the Hewlett-Packard (HP) Company. The native operating system for almost all HP 9000 systems is HP-UX, which is based on UNIX System V. |
Alloimmunity | Alloimmunity (sometimes called isoimmunity) is an immune response to nonself antigens from members of the same species, which are called alloantigens or isoantigens. Two major types of alloantigens are blood group antigens and histocompatibility antigens. In alloimmunity, the body creates antibodies (called alloantibodies) against the alloantigens, attacking transfused blood, allotransplanted tissue, and even the fetus in some cases. Alloimmune (isoimmune) response results in graft rejection, which is manifested as deterioration or complete loss of graft function. In contrast, autoimmunity is an immune response to the self's own antigens. (The allo- prefix means "other", whereas the auto- prefix means "self".) Alloimmunization (isoimmunization) is the process of becoming alloimmune, that is, developing the relevant antibodies for the first time. |
Vans challenge | The Vans challenge is a viral internet challenge that began in March 2019 where people show their Vans shoes landing right-side up after tossing them in the air. The viral sensation reportedly started after a Twitter user shared a video of the occurrence, which was captioned: “Did you know it doesn’t matter how you throw your Vans they will land facing up.” Since then, multiple people on social media posted similar videos of them throwing their Vans in the air and landing right-side up, along with Crocs, UGG boots, and other popular shoes. This theory proved false, as these shoes have not always landed facing up after tossing them. |
Nut (climbing) | In rock climbing, a nut (or chock or chockstone) is a metal wedge threaded on a wire that climbers use for protection by wedging it into a crack in the rock. Quickdraws are clipped to the nut wire by the ascending climber and the rope threads through the quickdraw. Nuts come in a variety of sizes and styles, and several different brands are made by competing manufacturers. Most nuts are made of aluminum. Larger nuts may be threaded on Dyneema cord instead of wire, but this has become unusual.The very smallest nuts are known as micronuts and may be made of brass or other metal, and typically have their wires soldered into them, instead of looped through drilled holes. They are mostly used in aid climbing, and their value as protection, arresting a climber's fall, is marginal because of both their low breaking strength and their tiny surface area (the HB 0 measures about 4 x 7 x 2.5 mm) in contact with the rock, though this can be offset if several are placed at a time. Other names used include RPs (the brand name of the first commercially available micronuts) and brassies. They are available from several manufacturers in a variety of styles. British climbers in the 1950s and 1960s were the first to use nuts as climbing protection. In addition to using pitons, they picked up machine nuts from the side of railway tracks, climbed with them in their pockets, and used them as artificial chocks. This developed to the point where they drilled the thread from the middle, threaded them with slings, and used them in cracks. |
Dental papilla | In embryology and prenatal development, the dental papilla is a condensation of ectomesenchymal cells called odontoblasts, seen in histologic sections of a developing tooth. It lies below a cellular aggregation known as the enamel organ. The dental papilla appears after 8–10 weeks intra uteral life. The dental papilla gives rise to the dentin and pulp of a tooth.
The enamel organ, dental papilla, and dental follicle together forms one unit, called the tooth germ. This is of importance because all the tissues of a tooth and its supporting structures form from these distinct cellular aggregations. Similar to dental follicle, the dental papilla has a very rich blood supply and provides nutrition to the enamel organ. |
Behavioral momentum | Behavioral momentum is a theory in quantitative analysis of behavior and is a behavioral metaphor based on physical momentum. It describes the general relation between resistance to change (persistence of behavior) and the rate of reinforcement obtained in a given situation. |
Tropical Storm Greg | The name Greg has been used for eleven tropical cyclones worldwide: eight in the Eastern Pacific Ocean, two in the Australian region, and one in the Western Pacific. |
PDE8B | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B is an enzyme that in humans is encoded by the PDE8B gene. |
Solvent Yellow 124 | Solvent Yellow 124 is a yellow azo dye used in European Union as a fuel dye. It is a marker used since August 2002 to distinguish diesel fuel intended for heating from a higher-taxed motor diesel fuel. It is added to fuels not intended for motor vehicles in amounts of 6 mg/L or 7 mg/kg under the name Euromarker. |
Swfdec | Swfdec is an outdated free and open-source replacement for Adobe Flash Player. It runs on Linux and FreeBSD and is distributed under the terms of the GNU Lesser General Public License (LGPL). Its last release was 0.8.4, on December 21, 2008 (2008-12-21) and latest in stable 0.9.2 of 2008-11-11.
Development of Swfdec has stopped. As of March 2016, the most recent commit to its Git repository was in December 2009. |
Pullback (category theory) | In category theory, a branch of mathematics, a pullback (also called a fiber product, fibre product, fibered product or Cartesian square) is the limit of a diagram consisting of two morphisms f : X → Z and g : Y → Z with a common codomain. The pullback is written P = X ×f, Z, g Y.Usually the morphisms f and g are omitted from the notation, and then the pullback is written P = X ×Z Y.The pullback comes equipped with two natural morphisms P → X and P → Y. The pullback of two morphisms f and g need not exist, but if it does, it is essentially uniquely defined by the two morphisms. In many situations, X ×Z Y may intuitively be thought of as consisting of pairs of elements (x, y) with x in X, y in Y, and f(x) = g(y). For the general definition, a universal property is used, which essentially expresses the fact that the pullback is the "most general" way to complete the two given morphisms to a commutative square. |
Vaginal artery | The vaginal artery is an artery in females that supplies blood to the vagina and the base of the bladder. |
External intercostal muscles | The external intercostal muscles, or external intercostals (Intercostales externi) are eleven in number on both sides. |
EMBnet | The European Molecular Biology network (EMBnet) is an international scientific network and interest group that aims to enhance bioinformatics services by bringing together bioinformatics expertises and capacities. On 2011 EMBnet has 37 nodes spread over 32 countries. The nodes include bioinformatics related university departments, research institutes and national service providers. |
Phenomenology (architecture) | Architectural phenomenology is the discursive and realist attempt to understand and embody the philosophical insights of phenomenology within the discipline of architecture. The phenomenology of architecture is the philosophical study of architecture employing the methods of phenomenology. |
Histotrophy | Histotrophy is a form of matrotrophy exhibited by some live-bearing sharks and rays, in which the developing embryo receives additional nutrition from its mother in the form of uterine secretions, known as histotroph (or "uterine milk"). It is one of the three major modes of elasmobranch reproduction encompassed by "aplacental viviparity", and can be contrasted with yolk-sac viviparity (in which the embryo is solely sustained by yolk) and oophagy (in which the embryo feeds on ova). |
Gbcast | Gbcast (also known as group broadcast) is a reliable multicast protocol that provides ordered, fault-tolerant (all-or-none) message delivery in a group of receivers within a network of machines that experience crash failure. The protocol is capable of solving Consensus in a network of unreliable processors, and can be used to implement state machine replication. Gbcast can be used in a standalone manner, or can support the virtual synchrony execution model, in which case Gbcast is normally used for group membership management while other, faster, protocols are often favored for routine communication tasks. |
S-Ethylisothiouronium diethylphosphate | S-Ethylisothiouronium diethylphosphate (brand name Difetur) is an S-alkylisothiouronium derivative used as an antihypotensive drug. The S-alkylisothiouronium compounds are used in processes of treating acute hypotension, which may result, for example, from shock or hemorrhage, and in processes for treating hyperoxic conditions, for example, oxygen poisoning. |
Maximal compact subgroup | In mathematics, a maximal compact subgroup K of a topological group G is a subgroup K that is a compact space, in the subspace topology, and maximal amongst such subgroups.
Maximal compact subgroups play an important role in the classification of Lie groups and especially semi-simple Lie groups. Maximal compact subgroups of Lie groups are not in general unique, but are unique up to conjugation – they are essentially unique. |
RDH11 | Retinol dehydrogenase 11 is an enzyme that in humans is encoded by the RDH11 gene.RHD11, a member of the short-chain dehydrogenase/reductase (SDR) superfamily of oxidoreductases, is expressed at high levels in prostate epithelium, and its expression is regulated by androgens.[supplied by OMIM] |
Glucose-6-phosphate dehydrogenase (coenzyme-F420) | Glucose-6-phosphate dehydrogenase (coenzyme-F420) (EC 1.1.98.2, coenzyme F420-dependent glucose-6-phosphate dehydrogenase, F420-dependent glucose-6-phosphate dehydrogenase, FGD1, Rv0407, F420-dependent glucose-6-phosphate dehydrogenase 1) is an enzyme with systematic name D-glucose-6-phosphate:F420 1-oxidoreductase. This enzyme catalyses the following chemical reaction D-glucose 6-phosphate + oxidized coenzyme F420 ⇌ 6-phospho-D-glucono-1,5-lactone + reduced coenzyme F420Thus enzyme is specific for D-glucose 6-phosphate. |
Dismasting | Dismasting, also spelled demasting, occurs to a sailing ship when one or more of the masts responsible for hoisting the sails that propel the vessel breaks. Dismasting usually occurs as the result of high winds during a storm acting upon masts, sails, rigging, and spars. Over compression of the mast owing to tightening the rigger too much and g-forces as a consequence of wave action and the boat swinging back and forth can also result in a dismasting. Dismasting does not necessarily impair the vessel's ability to stay afloat, but rather its ability to move under sail power. Frequently, the hull of the vessel remains intact, upright and seaworthy. |
RealPC | RealPC was a Macintosh program that emulates an x86 PC, allowing the use of MS-DOS, Windows NT, Windows 95, and Windows 98. RealPC was compatible with PowerPC Macs running system software 7.1.2 through 9.2. Requirements were: Any Power Macintosh or Mac OS compatible, System 7.1.2 or later, Minimum 16 Mbytes of Ram, hard drive space for 50 Mbytes (MS-DOS), 60 Mbytes (Windows 3.x), 130 Mbytes (Windows 95), and any Macintosh compatible CD-ROM drive. RealPC emulated a Pentium-based PC with MMX technology, supported Sound Blaster and MMX, and allowed you to use a Macintosh joystick, allowing you to run PC programs, including MS-DOS, and Windows, games and applications, alongside your existing Macintosh applications. RealPC was provided with MS-DOS 6.22 already installed, so you could immediately run MS-DOS games and applications on your Macintosh. Linux was not supported and due to shared RAM between Mac OS and RealPC Windows 98 was the reasonable limit. RealPC was able to convert Virtual-PC hard disk files to use and run the installed OS. |
Isovalent hybridization | In chemistry, isovalent or second order hybridization is an extension of orbital hybridization, the mixing of atomic orbitals into hybrid orbitals which can form chemical bonds, to include fractional numbers of atomic orbitals of each type (s, p, d). It allows for a quantitative depiction of bond formation when the molecular geometry deviates from ideal bond angles. |
Capsid | A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The capsid and inner genome is called the nucleocapsid. |
IRows | iRows was a web-based spreadsheet in beta with a GUI similar to the traditional desktop-based spreadsheet applications, such as Microsoft Excel and OpenOffice.org. It was shut down on December 31, 2006, after it was announced that its two founders had been hired by Google.iRows used Ajax and XML. It was described as an example of a Web 2.0 system.
iRows supported conventional spreadsheet features functions, value formatting and charts and added web oriented spreadsheet capabilities like collaboration (multiple people using a shared spreadsheet, sending a spreadsheet as a link instead of an attachment and ability to publish spreadsheets on other web pages (e.g. blogs). |
R-factor (crystallography) | In crystallography, the R-factor (sometimes called residual factor or reliability factor or the R-value or RWork) is a measure of the agreement between the crystallographic model and the experimental X-ray diffraction data. In other words, it is a measure of how well the refined structure predicts the observed data. The value is also sometimes called the discrepancy index, as it mathematically describes the difference between the experimental observations and the ideal calculated values. It is defined by the following equation: obs calc obs |, where F is the so-called structure factor and the sum extends over all the reflections of X-rays measured and their calculated counterparts respectively. The structure factor is closely related to the intensity of the reflection it describes: Ihkl∝|F(hkl)|2 .The minimum possible value is zero, indicating perfect agreement between experimental observations and the structure factors predicted from the model. There is no theoretical maximum, but in practice, values are considerably less than one even for poor models, provided the model includes a suitable scale factor. Random experimental errors in the data contribute to R even for a perfect model, and these have more leverage when the data are weak or few, such as for a low-resolution data set. Model inadequacies such as incorrect or missing parts and unmodeled disorder are the other main contributors to R , making it useful to assess the progress and final result of a crystallographic model refinement. For large molecules, the R-factor usually ranges between 0.6 (when computed for a random model and against an experimental data set) and 0.2 (for example for a well refined macro-molecular model at a resolution of 2.5 Ångström). Small molecules (up to ca. 1000 atoms) usually form better-ordered crystals than large molecules, and thus it is possible to attain lower R-factors. In the Cambridge Structural Database of small-molecule structures, more than 95% of the 500,000+ crystals have an R-factor lower than 0.15, and 9.5% have an R-factor lower than 0.03. |
Selenite (mineral) | Selenite, satin spar, desert rose, gypsum flower are crystal habit varieties of the mineral gypsum.
All varieties of gypsum, including selenite and alabaster, are composed of calcium sulfate dihydrate (meaning that it has two molecules of water), with the chemical formula CaSO4·2H2O. Selenite contains no significant selenium – The similar names both derive from Greek selḗnē (σελήνη 'Moon').
Some of the largest crystals ever found are of selenite, the largest specimen found in the Naica Mine's Cave of the Crystals being 12 metres long and weighing 55 tons. |
Comparison of mobile operating systems | This is a comparison on mobile operating systems. Only the latest versions are shown in the table below, even though older versions may still be marketed. |
Quine–McCluskey algorithm | The Quine–McCluskey algorithm (QMC), also known as the method of prime implicants, is a method used for minimization of Boolean functions that was developed by Willard V. Quine in 1952 and extended by Edward J. McCluskey in 1956. As a general principle this approach had already been demonstrated by the logician Hugh McColl in 1878, was proved by Archie Blake in 1937, and was rediscovered by Edward W. Samson and Burton E. Mills in 1954 and by Raymond J. Nelson in 1955. Also in 1955, Paul W. Abrahams and John G. Nordahl as well as Albert A. Mullin and Wayne G. Kellner proposed a decimal variant of the method.The Quine–McCluskey algorithm is functionally identical to Karnaugh mapping, but the tabular form makes it more efficient for use in computer algorithms, and it also gives a deterministic way to check that the minimal form of a Boolean function has been reached. It is sometimes referred to as the tabulation method. |
RAML (software) | RESTful API Modeling Language (RAML) is a YAML-based language for describing static APIs (but not REST APIs). It provides all the information necessary to describe APIs on the level 2 of the Richardson Maturity Model. Although designed with RESTful APIs in mind, RAML is not capable of describing APIs that obey all constraints of REST (it cannot describe an API obeying HATEOAS, in particular). It encourages reuse, enables discovery and pattern-sharing and aims for merit-based emergence of best practices. |
Body marbling | Body marbling is a painting process similar to paper marbling, in which paint is floated on water and transferred to a person's skin. Unlike the traditional oil-based technique for paper, neon or ultraviolet reactive colours are typically used, and the paint is water-based and non-toxic. The term "body marbling" was coined in 2011 by Brad Lawrence of Black Light Visuals. Body marbling has become popular at festivals. |
Kepler-33b | Kepler-33b is an extrasolar planet orbiting Kepler-33 in the constellation Cygnus. It is one of five planets orbiting Kepler-33. |
Deck tennis | Deck tennis is a sport that is played by mariners on the decks of both cargo and passenger vessels. The sport is a hybrid between tennis and quoits, and is played with either the rubber disk or ring, or a similarly-sized rope ring. The sport has been standardized and formalized in several countries under names such as "tennikoit" or "ring tennis". |
Reports on Progress in Physics | Reports on Progress in Physics is a monthly peer-reviewed scientific journal published by IOP Publishing. The editor-in-chief as of 2022 is Subir Sachdev (Harvard University). |
Alpha,N-DMT | Alpha,N-DMT, or α,N-dimethyltryptamine, is a lesser-known psychedelic drug. It is the α,N-dimethyl analog of DMT. α,N-DMT was first synthesized by Alexander Shulgin. In his book TiHKAL (Tryptamines I Have Known and Loved), Shulgin lists the dosage as 50-100 mg, and the duration as 6–8 hours. α,N-DMT causes an unpleasant body load. Very little data exists about the pharmacological properties, metabolism, and toxicity of α,N-DMT. α,N-DMT is known to be a potent monoamine oxidase inhibitor |
Lunate | Lunate is a crescent or moon-shaped microlith. In the specialized terminology of lithic reduction, a lunate flake is a small, crescent-shaped flake removed from a stone tool during the process of pressure flaking.
In the Natufian period, a lunate was a small crescent-shaped stone tool that was sometimes used to harvest grasses.
In archaeology a lunate is a small stone artifact, that has a sharpened straight edge and a blunt crescent shaped back. The word originates from the Latin word lunatus which means to bend like a crescent, and from luna meaning moon in Latin. A lunate object can be typically used as a decorative piece or as a stone tool. |
MreB | MreB is a protein found in bacteria that has been identified as a homologue of actin, as indicated by similarities in tertiary structure and conservation of active site peptide sequence. The conservation of protein structure suggests the common ancestry of the cytoskeletal elements formed by actin, found in eukaryotes, and MreB, found in prokaryotes. Indeed, recent studies have found that MreB proteins polymerize to form filaments that are similar to actin microfilaments. It has been shown to form multilayer sheets comprising diagonally interwoven filaments in the presence of ATP or GTP.MreB along with MreC and MreD are named after the mre operon (murein formation gene cluster E) to which they all belong. |
Hydranencephaly | Hydranencephaly is a condition in which the brain's cerebral hemispheres are absent to a great degree and the remaining cranial cavity is filled with cerebrospinal fluid. "Cephalic" is the scientific term for "head" or "head end of body". |
Jumping translocation breakpoint | The jumping translocation breakpoint protein (JTB), also known as prostate androgen-regulated protein (PAR), is a protein that in humans is encoded by the JTB gene. It is an orphan receptor with unknown function.The JTB family of proteins contains several jumping translocation breakpoint proteins or JTBs. Jumping translocation (JT) is an unbalanced translocation that comprises amplified chromosomal segments jumping to various telomeres. JTB has been found to fuse with the telomeric repeats of acceptor telomeres in a case of JT. Homo sapiens JTB (hJTB) encodes a transmembrane protein that is highly conserved among divergent eukaryotic species. JT results in a hJTB truncation, which potentially produces an hJTB product devoid of the transmembrane domain. hJTB is located in a gene-rich region at 1q21, called epidermal differentiation complex (EDC). JTB has also been implicated in prostatic carcinomas. |
NAD+ Five-prime cap | In molecular biology, the NAD+ five-prime cap (NAD+ 5’ cap) refers to a molecule of nicotinamide adenine dinucleotide (NAD+), a nucleoside-containing metabolite, covalently bonded the 5’ end of cellular mRNA. While the more common methylated guanosine (m7G) cap is added to RNA by a capping complex that associates with RNA polymerase II (RNAP II), the NAD cap is added during transcriptional initiation by the RNA polymerase itself, acting as a non-canonical initiating nucleotide (NCIN). As such, while m7G capping can only occur in organisms possessing specialized capping complexes, because NAD capping is performed by RNAP itself, it is hypothesized to occur in most, if not all, organisms.The NAD+ 5’ cap has been observed in bacteria, contrary to the long-held belief that prokaryotes lacked 5’-capped RNA, as well as on the 5’ cap of eukaryotic mRNA, in place of the m7G cap. This modification also potentially allows for selective degradation of RNA]within prokaryotes as different pathways are involved in the degradation of NAD+-capped and uncapped 5′-triphosphate-RNAs. |
Pablo Sinues | Pablo Sinues (also published as Pablo Martinez-Lozano Sinues) is an associate professor at the Department of Biomedical Engineering at the University of Basel (Basel, Switzerland) and lecturer at the Department of Chemistry and Applied Biosciences at ETH Zürich. He received his Ph.D. in Mechanical Engineering from the Charles III University of Madrid (Spain) and Habilitation in Analytical Chemistry at ETH Zürich. Sinues heads the Translational Breath Research group located at the University Children’s Hospital Basel |
Pickup truck racing | Pickup truck racing is a form of auto racing which involves modified versions of pickup trucks on racing circuits, mostly oval tracks. Race pickup trucks are mechanically similar to coupé-shaped stock cars, with the main difference being the more boxy shape of the cab, which does not have as good aerodynamics as stock cars.
NASCAR Truck Series vehicles have been rapidly evolving since the inception of the series in 1995, in terms of speed, aerodynamics, and engine equipment. The NASCAR series was also the first to use this type of vehicle, unveiled in 1994. |
Bottom simulating reflector | Bottom simulating reflectors (BSRs) are, on seismic reflection profiles, shallow seismic reflection events, characterized by their reflection geometry similar to seafloor bathymetry.
. They have, however, the opposite reflection polarity to the seabed reflection, and frequently intersect the primary reflections. |
Apple Icon Image format | The Apple Icon Image format is an icon format used in Apple Inc.'s macOS. It supports icons of 16 × 16, 32 × 32, 48 × 48, 128 × 128, 256 × 256, 512 × 512 points at 1x and 2x scale, with both 1- and 8-bit alpha channels and multiple image states (example: open and closed folders). The fixed-size icons can be scaled by the operating system and displayed at any intermediate size. |
DOT pictograms | The DOT pictograms are a set of fifty pictograms used to convey information useful to travelers without using words. Such images are often used in airports, train stations, hotels, and other public places for foreign tourists, as well as being easier to identify than strings of text. Among these pictograms are graphics representing toilets and telephones. As a result of their near-universal acceptance, some describe them as the "Helvetica" of pictograms, and the character portrayed within them as Helvetica Man.As works of the United States government, the images are in the public domain and thus can be used by anyone for any purpose, without licensing issues. |
Dental trauma | Dental trauma refers to trauma (injury) to the teeth and/or periodontium (gums, periodontal ligament, alveolar bone), and nearby soft tissues such as the lips, tongue, etc. The study of dental trauma is called dental traumatology. |
MacTalk Australia | MacTalk Australia was an online forum dedicated to news, support & discussion amongst Apple enthusiasts or potential users, with an Australian bias.
After its inception in 2004, the forum quickly became a top 10 tech site receiving hundreds of thousands of visits per month. In 2011 the site was sold to Niche Media, owner of Macworld Australia Magazine, and by 2015 a message by the sites' volunteer moderators declared the site dead. |
DPP7 | Dipeptidyl-peptidase 2 is an enzyme that in humans is encoded by the DPP7 gene.The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolyl carboxypeptidase and is active at both acidic and neutral pH. |
Radeon HD 5000 series | The Evergreen series is a family of GPUs developed by Advanced Micro Devices for its Radeon line under the ATI brand name. It was employed in Radeon HD 5000 graphics card series and competed directly with Nvidia's GeForce 400 Series. |
Map seed | In video games using procedural world generation, the map seed is a (relatively) short number or text string which is used to procedurally create the game world ("map"). This means that while the seed-unique generated map may be many megabytes in size (often generated incrementally and virtually unlimited in potential size), it is possible to reset to the unmodified map, or the unmodified map can be exchanged between players, just by specifying the map seed. An example of a map seed in Minecraft is "-2242547518357798464". Map seeds are a type of random seeds. |
Jewish mystical exegesis | Jewish mystical exegesis is a method of interpreting the Bible based on the assumption that the Torah contains secret knowledge regarding creation and the manifestations of God. The only way to find these secrets is to know how to decode the text and reveal them. The method most likely dates back to the 3rd century. |
Short Message Peer-to-Peer | Short Message Peer-to-Peer (SMPP) in the telecommunications industry is an open, industry standard protocol designed to provide a flexible data communication interface for the transfer of short message data between External Short Messaging Entities (ESMEs), Routing Entities (REs) and SMSC.SMPP is often used to allow third parties (e.g. value-added service providers like news organizations) to submit messages, often in bulk, but it may be used for SMS peering as well. SMPP is able to carry short messages including EMS, voicemail notifications, Cell Broadcasts, WAP messages including WAP Push messages (used to deliver MMS notifications), USSD messages and others. Because of its versatility and support for non-GSM SMS protocols, like UMTS, IS-95 (CDMA), CDMA2000, ANSI-136 (TDMA) and iDEN, SMPP is the most commonly used protocol for short message exchange outside SS7 networks. |
EA-2012 | EA-2012 is an extremely toxic organophosphate nerve agent. It's an extremely potent acetylcholinesterase inhibitor that is resistant to atropine and oxime treatment. |
Pixia | Pixia is a freeware raster graphics editor program for Windows, created by Isao Maruoka. It was originally designed for the anime/manga community but has also been used in other branches of art. Besides the primary Japanese interface, it is also available in English, French, Italian, Spanish, Hungarian, Chinese Simplified, Chinese Traditional, Polish, Korean and German. The program supports multiple layers, transparency effects, standard file formats and a number of RGB file formats including .PSD. The main file extension used by this program is .PXA. The program also has a native support for Wacom tablets, for example the 4.2a version added support for Wacom Bamboo tablets. An advanced version of this software called Phierha with better UI and more functions is also available. |
AppleColor High-Resolution RGB Monitor | Apple Inc. sold a variety of LCD and CRT computer displays in the past. Apple paused production of their own standalone displays in 2016 and partnered with LG to design displays for Macs. In June 2019, the Pro Display XDR was introduced, however it was expensive and targeted for professionals. Nearly three years later, in March 2022, the Studio Display was launched as a consumer-targeted counterpart to the professional monitor. These two are currently the only Apple-branded displays available. |
Benesi–Hildebrand method | The Benesi–Hildebrand method is a mathematical approach used in physical chemistry for the determination of the equilibrium constant K and stoichiometry of non-bonding interactions. This method has been typically applied to reaction equilibria that form one-to-one complexes, such as charge-transfer complexes and host–guest molecular complexation. |
Birefringence | Birefringence is the optical property of a material having a refractive index that depends on the polarization and propagation direction of light. These optically anisotropic materials are said to be birefringent (or birefractive). The birefringence is often quantified as the maximum difference between refractive indices exhibited by the material. Crystals with non-cubic crystal structures are often birefringent, as are plastics under mechanical stress. Birefringence is responsible for the phenomenon of double refraction whereby a ray of light, when incident upon a birefringent material, is split by polarization into two rays taking slightly different paths. This effect was first described by Danish scientist Rasmus Bartholin in 1669, who observed it in calcite crystals which have one of the strongest birefringences. In the 19th century Augustin-Jean Fresnel described the phenomenon in terms of polarization, understanding light as a wave with field components in transverse polarization (perpendicular to the direction of the wave vector). Birefringence plays an important role in achieving phase-matching for a number of nonlinear optical processes. |
Vacuum blasting | Vacuum blasting is an abrasive blasting method, also referred to as dustless blasting or closed loop abrasive blasting. The method is characterized by a blast tool that does abrasive blasting and collects both used blast media, and loosened particles from the surface to be treated, simultaneously. |
Myogel | Myogel is a trade name for a human-based extracellular matrix used in cancer research to provide a 3D cell culture environment for cancer cells. Unlike other synthesized matrices such as matrigel which originated from mice sarcoma, myogel is extracted from a human benign tumor tissue called leiomyoma. Myogel was developed in Tuula Salo's lab at the University of Oulu. The idea started in 2009 by culturing cancer cells on myoma discs. Later in 2015, these myoma tissues were processed following matrigel receipt, to extract a gel form called Myogel. Myogel was compared with matrigel and found to be superior in term of enhancing cancer cells proliferation, migration and invasion. |
Irene Tracey | Irene Mary Carmel Tracey (born 30 October 1966) is Vice-Chancellor of the University of Oxford and former Warden of Merton College, Oxford. She is also Professor of Anaesthetic Neuroscience in the Nuffield Department of Clinical Neurosciences and formerly Pro-Vice-Chancellor (without portfolio) at the University of Oxford. She is a co-founder of the Oxford Centre for Functional Magnetic Resonance Imaging of the Brain (FMRIB), now the Wellcome Centre for Integrative Neuroimaging. Her team’s research is focused on the neuroscience of pain, specifically pain perception and analgesia as well as how anaesthetics produce altered states of consciousness. Her team uses multidisciplinary approaches including neuroimaging. |
GNAT2 | Guanine nucleotide-binding protein G(t) subunit alpha-2 is a protein that in humans is encoded by the GNAT2 gene. |
Gluteal tuberosity | The gluteal tuberosity is the lateral one of the three upward prolongations of the linea aspera of the femur, extending to the base of the greater trochanter. It serves as the principal insertion site for the gluteus maximus muscle. |
Computers & Geosciences | Computers & Geosciences is a scientific journal published monthly by Elsevier on behalf of the International Association for Mathematical Geosciences. It contains research and review papers in computing applied to geosciences. Its impact factor is 3.372. |
Wilting | Wilting is the loss of rigidity of non-woody parts of plants. This occurs when the turgor pressure in non-lignified plant cells falls towards zero, as a result of diminished water in the cells. Wilting also serves to reduce water loss, as it makes the leaves expose less surface area. The rate of loss of water from the plant is greater than the absorption of water in the plant. The process of wilting modifies the leaf angle distribution of the plant (or canopy) towards more erectophile conditions. |
COVID-19 pandemic in Venezuela | The COVID-19 pandemic in Venezuela was a part of the worldwide pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first two cases in Venezuela were confirmed on 13 March 2020; the first death was reported on 26 March. However, the first record of a patient claiming to have symptoms of coronavirus disease dates back to 29 February 2020, with government officials suspecting that the first person carrying the virus could have entered the country as early as 25 February.Venezuela is particularly vulnerable to the wider effects of the pandemic because of its ongoing socioeconomic and political crisis causing massive shortages of food staples and basic necessities, including medical supplies. The mass emigration of Venezuelan doctors has also caused chronic staff shortages in hospitals.To prevent the spread of the disease into Venezuela, the governments of Brazil and Colombia temporarily closed their borders with Venezuela. The Colombian government had placed 1 October as a tentative date for reopening the border.In February 2021, Venezuela started vaccinations with the Russian Sputnik V COVID-19 vaccine and a vaccine produced by the Chinese company Sinopharm. It aimed to vaccinate 70 percent of the population by the end of 2021. An academic survey found that by the 1 September 2021, 10% of the Venezuelan population was fully vaccinated. By the end of 2021, Venezuela had administered 30,049,714 doses of vaccine, about 52.7% of the country's population. |
2CB-Ind | 2CB-Ind is a conformationally-restricted derivative of the phenethylamine hallucinogen 2C-B, discovered in 1974 by Alexander Shulgin. It acts as a moderately potent and selective agonist for the 5-HT2A and 5-HT2C receptors, but unlike the corresponding benzocyclobutene derivative TCB-2 which is considerably more potent than the parent compound 2C-B, 2CB-Ind is several times weaker, with racemic 2CB-Ind having a Ki of 47nM at the human 5-HT2A receptor, only slightly more potent than the mescaline analogue (R)-jimscaline. |
Glycoside hydrolase family 66 | In molecular biology, glycoside hydrolase family 66 is a family of glycoside hydrolases. |
Periodontal abscess | A periodontal abscess (also termed lateral abscess, or parietal abscess), is a localized collection of pus (i.e. an abscess) within the tissues of the periodontium. It is a type of dental abscess. A periodontal abscess occurs alongside a tooth, and is different from the more common periapical abscess, which represents the spread of infection from a dead tooth (i.e. which has undergone pulpal necrosis). To reflect this, sometimes the term "lateral (periodontal) abscess" is used. In contrast to a periapical abscess, periodontal abscesses are usually associated with a vital (living) tooth. Abscesses of the periodontium are acute bacterial infections classified primarily by location. |
Single-machine scheduling | Single-machine scheduling or single-resource scheduling is an optimization problem in computer science and operations research. We are given n jobs J1, J2, ..., Jn of varying processing times, which need to be scheduled on a single machine, in a way that optimizes a certain objective, such as the throughput. |
Cloroqualone | Cloroqualone is a quinazolinone-class GABAergic and is an analogue of methaqualone developed in the 1980s and marketed mainly in France and some other European countries. It has sedative and antitussive properties resulting from its agonist activity at the β subtype of the GABAa receptor and sigma-1 receptor, and was sold either alone or in combination with other ingredients as a cough medicine. Cloroqualone has weaker sedative properties than methaqualone and was sold for its useful cough-suppressing effects, but was withdrawn from the French market in 1994 because of concerns about its potential for abuse and overdose. |
Pedagogical relation | The pedagogical relation refers to special kind of personal relationship between adult and child or adult or student for the sake of the child or student. The pedagogical relation is described by Hermann Nohl, Klaus Mollenhauer, and others in the Northern European human science pedagogical tradition. It has been discussed more recently in English by Max van Manen, Norm Friesen, Tone Saevi and others.. |
Ro20-8552 | Ro20-8552 is a benzodiazepine derivative with sedative and anxiolytic effects, which has been sold as a designer drug. |
Polar amplification | Polar amplification is the phenomenon that any change in the net radiation balance (for example greenhouse intensification) tends to produce a larger change in temperature near the poles than in the planetary average. This is commonly referred to as the ratio of polar warming to tropical warming. On a planet with an atmosphere that can restrict emission of longwave radiation to space (a greenhouse effect), surface temperatures will be warmer than a simple planetary equilibrium temperature calculation would predict. Where the atmosphere or an extensive ocean is able to transport heat polewards, the poles will be warmer and equatorial regions cooler than their local net radiation balances would predict. The poles will experience the most cooling when the global-mean temperature is lower relative to a reference climate; alternatively, the poles will experience the greatest warming when the global-mean temperature is higher.In the extreme, the planet Venus is thought to have experienced a very large increase in greenhouse effect over its lifetime, so much so that its poles have warmed sufficiently to render its surface temperature effectively isothermal (no difference between poles and equator). On Earth, water vapor and trace gasses provide a lesser greenhouse effect, and the atmosphere and extensive oceans provide efficient poleward heat transport. Both palaeoclimate changes and recent global warming changes have exhibited strong polar amplification, as described below. |
Chi distribution | In probability theory and statistics, the chi distribution is a continuous probability distribution over the non-negative real line. It is the distribution of the positive square root of a sum of squared independent Gaussian random variables. Equivalently, it is the distribution of the Euclidean distance between a multivariate Gaussian random variable and the origin. It is thus related to the chi-squared distribution by describing the distribution of the positive square roots of a variable obeying a chi-squared distribution. |
Lattice model (finance) | In finance, a lattice model is a technique applied to the valuation of derivatives, where a discrete time model is required. For equity options, a typical example would be pricing an American option, where a decision as to option exercise is required at "all" times (any time) before and including maturity. A continuous model, on the other hand, such as Black–Scholes, would only allow for the valuation of European options, where exercise is on the option's maturity date. For interest rate derivatives lattices are additionally useful in that they address many of the issues encountered with continuous models, such as pull to par. The method is also used for valuing certain exotic options, where because of path dependence in the payoff, Monte Carlo methods for option pricing fail to account for optimal decisions to terminate the derivative by early exercise, though methods now exist for solving this problem. |
Barker's notation | Barker's notation refers to the ERD notation developed by Richard Barker, Ian Palmer, Harry Ellis et al. whilst working at the British consulting firm CACI around 1981. The notation was adopted by Barker when he joined Oracle and is effectively defined in his book Entity Relationship Modelling as part of the CASE Method series of books. This notation was and still is used by the Oracle CASE modelling tools. It is a variation of the "crows foot" style of data modelling that was favoured by many over the original Chen style of ERD modelling because of its readability and efficient use of drawing space. |
Memory refresh | Memory refresh is the process of periodically reading information from an area of computer memory and immediately rewriting the read information to the same area without modification, for the purpose of preserving the information. Memory refresh is a background maintenance process required during the operation of semiconductor dynamic random-access memory (DRAM), the most widely used type of computer memory, and in fact is the defining characteristic of this class of memory.In a DRAM chip, each bit of memory data is stored as the presence or absence of an electric charge on a small capacitor on the chip. As time passes, the charges in the memory cells leak away, so without being refreshed the stored data would eventually be lost. To prevent this, external circuitry periodically reads each cell and rewrites it, restoring the charge on the capacitor to its original level. Each memory refresh cycle refreshes a succeeding area of memory cells, thus repeatedly refreshing all the cells in a consecutive cycle. This process is conducted automatically in the background by the memory circuitry and is transparent to the user. While a refresh cycle is occurring the memory is not available for normal read and write operations, but in modern memory this "overhead" time is not large enough to significantly slow down memory operation. |
The International MS Journal | The International MS Journal is a medical journal published by Cambridge Medical Publications carrying reviews on multiple sclerosis. The journal, edited by Douglas Goodin, is also the host of MSForum.net |
Homicidal chauffeur problem | In game theory, the homicidal chauffeur problem is a mathematical pursuit problem which pits a hypothetical runner, who can only move slowly, but is highly maneuverable, against the driver of a motor vehicle, which is much faster but far less maneuverable, who is attempting to run him down. Both runner and driver are assumed to never tire. The question to be solved is: under what circumstances, and with what strategy, can the driver of the car guarantee that he can always catch the pedestrian, or the pedestrian guarantee that he can indefinitely elude the car? The problem is often used as an unclassified proxy for missile defense and other military targeting, allowing scientists to publish on it without security implications.The problem was proposed by Rufus Isaacs in a 1951 report for the RAND Corporation, and in the book Differential Games.The homicidal chauffeur problem is a classic example of a differential game played in continuous time in a continuous state space. The calculus of variations and level set methods can be used as a mathematical framework for investigating solutions of the problem. Although the problem is phrased as a recreational problem, it is an important model problem for mathematics used in a number of real-world applications. |
Queue area | Queue areas are places in which people queue (first-come, first-served) for goods or services. Such a group of people is known as a queue (British usage) or line (American usage), and the people are said to be waiting or standing in a queue or in line, respectively. (In the New York City area, the phrase on line is often used in place of in line.) Occasionally, both the British and American terms are combined to form the term "queue line".Examples include checking out groceries or other goods that have been collected in a self service shop, in a shop without self-service, at an ATM, at a ticket desk, a city bus, or in a taxi stand. |
Livestock dehorning | Dehorning is the process of removing the horns of livestock. Cattle, sheep, and goats are sometimes dehorned for economic and safety reasons. Disbudding is a different process with similar results; it cauterizes and thus destroys horn buds before they have grown into horns. Disbudding is commonly performed early in an animal's life, as are other procedures such as docking and castration. In some cases, it can be unnecessary. |
Timeline of the COVID-19 pandemic in Turkey | This article documents the timeline of the COVID-19 pandemic in Turkey. |
Flame (malware) | Flame, also known as Flamer, sKyWIper, and Skywiper, is modular computer malware discovered in 2012 that attacks computers running the Microsoft Windows operating system. The program is used for targeted cyber espionage in Middle Eastern countries.Its discovery was announced on 28 May 2012 by the MAHER Center of the Iranian National Computer Emergency Response Team (CERT), Kaspersky Lab and CrySyS Lab of the Budapest University of Technology and Economics. The last of these stated in its report that Flame "is certainly the most sophisticated malware we encountered during our practice; arguably, it is the most complex malware ever found." Flame can spread to other systems over a local network (LAN). It can record audio, screenshots, keyboard activity and network traffic. The program also records Skype conversations and can turn infected computers into Bluetooth beacons which attempt to download contact information from nearby Bluetooth-enabled devices. This data, along with locally stored documents, is sent on to one of several command and control servers that are scattered around the world. The program then awaits further instructions from these servers.According to estimates by Kaspersky in May 2012, Flame had initially infected approximately 1,000 machines, with victims including governmental organizations, educational institutions and private individuals. At that time 65% of the infections happened in Iran, Israel, Palestine, Sudan, Syria, Lebanon, Saudi Arabia, and Egypt, with a "huge majority of targets" within Iran. Flame has also been reported in Europe and North America. Flame supports a "kill" command which wipes all traces of the malware from the computer. The initial infections of Flame stopped operating after its public exposure, and the "kill" command was sent.Flame is linked to the Equation Group by Kaspersky Lab. However, Costin Raiu, the director of Kaspersky Lab's global research and analysis team, believes the group only cooperates with the creators of Flame and Stuxnet from a position of superiority: "Equation Group are definitely the masters, and they are giving the others, maybe, bread crumbs. From time to time they are giving them some goodies to integrate into Stuxnet and Flame."In 2019, researchers Juan Andres Guerrero-Saade and Silas Cutler announced their discovery of the resurgence of Flame. The attackers used 'timestomping' to make the new samples look like they were created before the 'suicide' command. However, a compilation error included the real compilation date (circa 2014). The new version (dubbed 'Flame 2.0' by the researchers) includes new encryption and obfuscation mechanisms to hide its functionality. |
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