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Perinatal matrices | Perinatal matrices or basic perinatal matrices, in pre-perinatal and transpersonal psychology, is a theoretical model of describing the state of awareness before and during birth.
In the context of perinatal psychology, perinatal matrices refer to the psychological and emotional experiences and imprints that occur during the prenatal and birth process. It is believed that these early experiences have a significant impact on an individual's development, personality, and well-being throughout their life. |
KZ Andromedae | KZ Andromedae (often abbreviated to KZ And) is a double lined spectroscopic binary in the constellation Andromeda. Its apparent visual magnitude varies between 7.91 and 8.03 during a cycle slightly longer than 3 days. |
Calreticulin protein family | In molecular biology, the calreticulin protein family is a family of calcium-binding proteins. This family includes Calreticulin, Calnexin and Camlegin. |
Metamfepramone | Metamfepramone (INN, also known as dimethylcathinone, dimethylpropion, and dimepropion (BAN)) is a stimulant drug of the phenethylamine, and cathinone chemical classes. Dimethylcathinone was evaluated as an appetite suppressant and for the treatment of hypotension, but was never widely marketed.It was used as a recreational drug in Israel under the name rakefet, but was made illegal in 2006.Metamfepramone is metabolized to produce N-methylpseudoephedrine and methcathinone. It has also been found to be about 1.6 times less potent than methcathinone, making it roughly equipotent to cathinone itself. |
Luchacovirus | Luchacovirus is a subgenus of viruses in the genus Alphacoronavirus, consisting of a single species, Lucheng Rn rat coronavirus. |
Opigolix | Opigolix (INN, USAN; developmental code name ASP-1707) is a small-molecule, non-peptide, orally active gonadotropin-releasing hormone antagonist (GnRH antagonist) which was under development by Astellas Pharma for the treatment of endometriosis and rheumatoid arthritis. It was also under investigation for the treatment of prostate cancer. It reached phase II clinical trials for both endometriosis and rheumatoid arthritis prior to the discontinuation of its development in April 2018. |
Suffix automaton | In computer science, a suffix automaton is an efficient data structure for representing the substring index of a given string which allows the storage, processing, and retrieval of compressed information about all its substrings. The suffix automaton of a string S is the smallest directed acyclic graph with a dedicated initial vertex and a set of "final" vertices, such that paths from the initial vertex to final vertices represent the suffixes of the string. |
Metadesign | Metadesign (or meta-design) is an emerging conceptual framework aimed at defining and creating social, economic and technical infrastructures in which new forms of collaborative design can take place. It consists of a series of practical design-related tools for achieving this.
As a methodology, its aim is to nurture emergence of the previously unthinkable as possibilities or prospects through the collaboration of designers within interdisciplinarity 'metadesign' teams. Inspired by the way living systems work, this new field aims to help improve the way we feed, clothe, shelter, assemble, communicate and live together. |
Embryo quality | Embryo quality is the ability of an embryo to perform successfully in terms of conferring a high pregnancy rate and/or resulting in a healthy person. Embryo profiling is the estimation of embryo quality by qualification and/or quantification of various parameters. Estimations of embryo quality guides the choice in embryo selection in in vitro fertilization. |
Aromatic amine | In organic chemistry, an aromatic amine is an organic compound consisting of an aromatic ring attached to an amine. It is a broad class of compounds that encompasses anilines, but also many more complex aromatic rings and many amine substituents beyond NH2. Such compounds occur widely.
Aromatic amines are widely used as precursor to pesticides, pharmaceuticals, and dyes. |
Marilyn Walker | Marilyn A. Walker is an American computer scientist. She is professor of computer science and head of the Natural Language and Dialogue Systems Lab at the University of California, Santa Cruz (UCSC). Her research includes work on computational models of dialogue interaction and conversational agents, analysis of affect, sarcasm and other social phenomena in social media dialogue, acquiring causal knowledge from text, conversational summarization, interactive story and narrative generation, and statistical methods for training the dialogue manager and the language generation engine for dialogue systems. |
Shooting guard | The shooting guard (SG), also known as the two, two guard or off guard, is one of the five traditional positions in a regulation basketball game. A shooting guard's main objective is to score points for their team and steal the ball on defense. Some teams ask their shooting guards to bring up the ball as well; these players are known colloquially as combo guards. A player who can switch between playing shooting guard and small forward is known as a swingman. In the NBA, shooting guards usually range from 6 ft 4 in (1.93 m) to 6 ft 6 in (1.98 m) while in the WNBA, shooting guards tend to be between 5 ft 10 in (1.78 m) and 6 ft 1 in (1.85 m). |
Ferrihydrite | Ferrihydrite (Fh) is a widespread hydrous ferric oxyhydroxide mineral at the Earth's surface, and a likely constituent in extraterrestrial materials. It forms in several types of environments, from freshwater to marine systems, aquifers to hydrothermal hot springs and scales, soils, and areas affected by mining. It can be precipitated directly from oxygenated iron-rich aqueous solutions, or by bacteria either as a result of a metabolic activity or passive sorption of dissolved iron followed by nucleation reactions. Ferrihydrite also occurs in the core of the ferritin protein from many living organisms, for the purpose of intra-cellular iron storage. |
Sunflower trypsin inhibitor | Sunflower trypsin inhibitor (SFTI) is a small, circular peptide produced in sunflower seeds, and is a potent inhibitor of trypsin. It is the smallest known member of the Bowman-Birk family of serine protease inhibitors.One example of Sunflower trypsin inhibitor is Sunflower trypsin inhibitor-1 (SFTI-1). Sunflower trypsin inhibitor-1 is a potent Bowman-Birk inhibitor. Sunflower trypsin inhibitor-1 is the simplest cysteine-rich peptide scaffold because it is a bicyclic 14 amino acid peptide and only has one disulfide bond. The disulfide bond divides the peptide into two loops. One loop is a functional trypsin inhibitory and the second loop is a nonfunctional loop. The nonfunctional loop can be replaced by a bioactive loop. It is extracted from a seed of a sunflower called Helianthus annuus. The synthesis of SFTI is not known however, it can evolutionarily linked to a gene-coded product from classic Bowman-Birk inhibitors. STFI is used in radiopharmaceutical, antimicrobial, and pro-angiogenic peptides. |
Microbiologist | A microbiologist (from Greek μῑκρος) is a scientist who studies microscopic life forms and processes. This includes study of the growth, interactions and characteristics of microscopic organisms such as bacteria, algae, fungi, and some types of parasites and their vectors. Most microbiologists work in offices and/or research facilities, both in private biotechnology companies and in academia. Most microbiologists specialize in a given topic within microbiology such as bacteriology, parasitology, virology, or immunology. |
Pre-Lie algebra | In mathematics, a pre-Lie algebra is an algebraic structure on a vector space that describes some properties of objects such as rooted trees and vector fields on affine space.
The notion of pre-Lie algebra has been introduced by Murray Gerstenhaber in his work on deformations of algebras.
Pre-Lie algebras have been considered under some other names, among which one can cite left-symmetric algebras, right-symmetric algebras or Vinberg algebras. |
Neointima | Neointima typically refers to scar tissue that forms within tubular anatomical structures such as blood vessels, as the intima is the innermost lining of these structures. Neointima can form as a result of vascular surgery such as angioplasty or stent placement. It is actually due to proliferation of smooth muscle cells in the media giving rise to appearance of fused intima and media |
Causalism | Causalism holds behavior and actions to be the result of previous mental states, such as beliefs, desires, or intentions, rather than from a present conscious will guiding one's actions. One of the foremost proponents for this view was Donald Davidson (philosopher), who believed "that reasons explain actions just inasmuch as they are the causes of those actions". His views were mainly set out in his famous paper ‘Actions, Reasons and Causes’ (1963).Causalism is in accord with how most people have traditionally explained their actions, but critics point out that certain habitual actions such as scratching an itch are only noticed during or after the fact, if at all, making the causalist explanation that such behaviors have a mental antecedent that isn’t recalled seem ad hoc. |
Invention (musical composition) | In music, an invention is a short composition (usually for a keyboard instrument) in two-part counterpoint. (Compositions in the same style as an invention but using three-part counterpoint are known as sinfonias. Some modern publishers call them "three-part inventions" to avoid confusion with symphonies.) Well-known examples are the fifteen inventions that make up the first half of Johann Sebastian Bach's Inventions and Sinfonias. Inventions are usually not performed in public, but serve as exercises for keyboard students, and as pedagogical exercises for composition students. |
Transport in Shenzhen | Shenzhen has an extensive transport network, including various forms of land, water and air transport. |
Hatsumei Boy Kanipan | Hatsumei Boy Kanipan (発明BOYカニパン, Hatsumei Bōi Kanipan, trans. Inventor Boy Kanipan) is a 1998 Japanese anime television series produced by NAS and TV Tokyo and animated by Studio Comet. It was immediately followed by a second season titled Chō Hatsumei Boy Kanipan (超発明BOYカニパン, Chō Hatsumei Bōi Kanipan, trans. Super Inventor Boy Kanipan). In late 2000, Saban Entertainment licensed the series to air on Fox Kids in September 2001 but it did not air for unknown reasons. |
Probe card | A probe card (commonly referred to as a DUT board) is used in automated integrated circuit testing. It is an interface between an electronic test system and a semiconductor wafer. |
Nicocodeine | Nicocodeine (Lyopect, Tusscodin) is an opioid analgesic and cough suppressant, an ester of codeine closely related to dihydrocodeine and the codeine analogue of nicomorphine. It is not commonly used in most countries, but has activity similar to other opiates. Nicocodeine and nicomorphine were introduced in 1957 by Lannacher Heilmittel of Austria. Nicocodeine is metabolised in the liver by demethylation to produce nicomorphine, also known as 6-nicotinoylmorphine, and subsequently further metabolised to morphine. Side effects are similar to those of other opiates and include itching, nausea and respiratory depression. Related opioid analogues such as nicomorphine and nicodicodeine were first synthesized. The definitive synthesis, which involves treating anhydrous codeine base with nicotinic anhydride at 130 °C, was published by Pongratz and Zirm in Monatshefte für Chemie in 1957, simultaneously with the two analogues in an article about amides and esters of various organic acids.Nicocodeine is almost always used as the hydrochloride salt, which has a free base conversion ratio of .917. In the past, the tartrate, bitartrate, phosphate, hydrobromide, methiodide, hydroiodide, and sulfate were used in research or as pharmaceuticals. |
Surface Mini | Surface Mini is an unreleased tablet computer that Microsoft designed as the successor to the Surface 2 in the Microsoft Surface family. The device has a Qualcomm Snapdragon 800 processor and a 7.5-inch (19 cm) 4:3 aspect ratio touchscreen display that defaults to portrait mode. Like its predecessor, the Surface Mini runs Windows RT 8.1, a mobile operating system that was designed for the ARM architecture and has limitations including an inability to install Win32 applications; programs can only be installed from the Windows Store. |
Graminoid | In botany and ecology, graminoid refers to a herbaceous plant with a grass-like morphology, i.e. elongated culms with long, blade-like leaves. They are contrasted to forbs, herbaceous plants without grass-like features.
The plants most often referred to include the families Poaceae (grasses in the strict sense), Cyperaceae (sedges), and Juncaceae (rushes). These are not closely related but belong to different clades in the order Poales. The grasses (Poaceae) are by far the largest family with some 12,000 species.
Besides their similar morphology, graminoids share the widespread occurrence and often dominance in open habitats such as grasslands or marshes. They can however also be found in the understory of forests. Sedges and rushes tend to prefer wetter habitats than grasses.
Examples of graminoid plants |
Angel Roleplaying Game | The Angel Roleplaying Game is a role-playing game published by Eden Studios, Inc. in 2003. |
Parametric determinism | Ernest Ezra Mandel (Dutch: [manˈdɛl]; also known by various pseudonyms such as Ernest Germain, Pierre Gousset, Henri Vallin, Walter (5 April 1923 – 20 July 1995), was a Belgian Marxian economist, Trotskyist activist and theorist, and Holocaust survivor. He fought in the underground resistance against the Nazis during the occupation of Belgium. |
Task (teaching style) | The Task teaching style is an option available to students under Student-Directed Teaching, a progressive teaching technology that aims to give the student a greater sense of ownership in his or her own education.
This teaching style is "for those students who required formal instruction and yet are capable of making some choice as to the appropriate practice for them to master the objective." This formal instruction happens at the same time as the Command students. |
Timehop | Timehop is an application for smartphones that collects old photos and posts from Facebook, Instagram, Twitter, Apple Photos, Google Photos and Dropbox photos and distributes the past.
The company was founded in 2011 by Jonathan Wegener and Benny Wong. As of January 2016, Timehop had 12 million users. |
Meteotsunami | A meteotsunami or meteorological tsunami is a tsunami-like sea wave of meteorological origin. Meteotsunamis are generated when rapid changes in barometric pressure cause the displacement of a body of water. In contrast to "ordinary" impulse-type tsunami sources, a traveling atmospheric disturbance normally interacts with the ocean over a limited period of time (from several minutes to several hours). Tsunamis and meteotsunamis are otherwise similar enough that it can be difficult to distinguish one from the other, as in cases where there is a tsunami wave but there are no records of an earthquake, landslide, or volcanic eruption.: 1036 Meteotsunamis, rather, are triggered due to extreme weather events including severe thunderstorms, squalls and storm fronts; all of which can quickly change atmospheric pressure. Meteotsunamis typically occur when severe weather is moving at the same speed and direction of the local wave action towards the coastline. The size of the wave is enhanced by coastal features such as shallow continental shelves, bays and inlets.Only about 3% of historical tsunami events (from 2000 BC through 2014) are known to have meteorological origins, although their true prevalence may be considerably higher than this because 10% of historical tsunamis have unknown origins, tsunami events in the past are often difficult to validate, and meteotsunamis may have previously been misclassified as seiche waves. Seiches are classified as a long-standing wave with longer periods and slower changes in water levels. They are also restricted to enclosed or partially enclosed basins. |
GDP-D-glucose phosphorylase | GDP-D-glucose phosphorylase (EC 2.7.7.78) is an enzyme with systematic name GDP:alpha-D-glucose 1-phosphate guanylyltransferase. This enzyme catalyses the following chemical reaction GDP-alpha-D-glucose + phosphate ⇌ alpha-D-glucose 1-phosphate + GDPThe enzyme may be involved in prevention of misincorporation of glucose in place of mannose residues into glycoconjugates. |
Progestogen ester | A progestogen ester is an ester of a progestogen or progestin (a synthetic progestogen). The prototypical progestogen is progesterone, an endogenous sex hormone. Esterification is frequently employed to improve the pharmacokinetics of steroids, including oral bioavailability, lipophilicity, and elimination half-life. In addition, with intramuscular injection, steroid esters are often absorbed more slowly into the body, allowing for less frequent administration. Many (though not all) steroid esters function as prodrugs. |
MILEPOST GCC | MILEPOST GCC is a free, community-driven, open-source, adaptive, self-tuning compiler that combines stable production-quality GCC, Interactive Compilation Interface and machine learning plugins to adapt to any given architecture and program automatically and predict profitable optimizations to improve program execution time, code size and compilation time. It is currently used and supported by academia and industry and is intended to open up research opportunities to automate compiler and architecture design and optimization.MILEPOST GCC is currently a part of the community-driven Collective Tuning Initiative (cTuning) to enable self-tuning computing systems based on collaborative open-source R&D infrastructure with unified interfaces and to improve the quality and reproducibility of research on code and architecture optimization. MILEPOST GCC is connected with the Collective Optimization Database to collect and reuse profitable optimization cases from the community and predict high-quality optimizations based on statistical analysis of past optimization data. |
Hemotoxin | Hemotoxins, haemotoxins or hematotoxins are toxins that destroy red blood cells, disrupt blood clotting, and/or cause organ degeneration and generalized tissue damage. The term hemotoxin is to some degree a misnomer since toxins that damage the blood also damage other tissues. Injury from a hemotoxic agent is often very painful and can cause permanent damage and in severe cases death. Loss of an affected limb is possible even with prompt treatment. |
No pain, no gain | No pain, no gain (or "No gain without pain") is a proverb, used since the 1980s as an exercise motto that promises greater value rewards for the price of hard and even painful work. Under this conception competitive professionals, such as athletes and artists, are required to endure pain (physical suffering) and stress (mental/emotional suffering) to achieve professional excellence. Medical experts agree that the proverb is wrong for exercise. |
Unconditional love | Unconditional love is known as affection without any limitations, or love without conditions. This term is sometimes associated with other terms such as true altruism or complete love. Each area of expertise has a certain way of describing unconditional love, but most will agree that it is that type of love which has no bounds and is unchanging. In Christianity, unconditional love is thought to be part of the Four Loves; affection, friendship, eros, and charity. In ethology, or the study of animal behavior, unconditional love would refer to altruism, which in turn refers to the behavior by individuals that increases the fitness of another while decreasing the fitness of the individual committing the act. In psychology, unconditional love refers to a state of mind in which one has the goal of increasing the welfare of another, despite the lack of any evidence of benefit for oneself. |
Catenin alpha-1 | αE-catenin, also known as Catenin alpha-1 is a protein that in humans is encoded by the CTNNA1 gene. αE-catenin is highly expressed in cardiac muscle and localizes to adherens junctions at intercalated disc structures where it functions to mediate the anchorage of actin filaments to the sarcolemma. αE-catenin also plays a role in tumor metastasis and skin cell function. |
Breast prostheses | Breast prostheses are breast forms intended to look like breasts. They are often used temporarily or permanently by women after mastectomy or lumpectomy procedures, but may also be used by for aesthetic purposes. There are a number of materials and designs; although, the most common construction is gel (silicone or water-based) in a plastic film meant to feel similar to a person's skin. Prostheses may be purchased at a surgical supply store, pharmacy, custom lingerie shop, or even through private services that come to a person's home. There are many types of ready made breast prostheses including full or standard prostheses, partial prostheses such a shell prostheses, and stick on prostheses. Customized options are also available from specialty shops, which are moulded to fit an individual's chest by taking an impression of the breast(s). The areola and nipple may be replicated as part of the breast form or as separate nipple prosthesis. Both custom made and off-the shelf breast prostheses come in varieties that are designed to either be held in a pocket in a specially designed mastectomy bra or attached to the skin via adhesive or other methods and worn with a standard bra. There are many factors to consider when selecting breast prostheses such as different types and the care they require, insurance coverage, and psychosocial effects. |
Adrian Kent | Adrian Kent is a British theoretical physicist, Professor of Quantum Physics at the University of Cambridge, member of the Centre for Quantum Information and Foundations, and Distinguished Visiting Research Chair at the Perimeter Institute for Theoretical Physics. His research areas are the foundations of quantum theory, quantum information science and quantum cryptography. He is known as the inventor of relativistic quantum cryptography. In 1999 he published the first unconditionally secure protocols for bit commitment and coin tossing, which were also the first relativistic cryptographic protocols. He is a co-inventor of quantum tagging, or quantum position authentication, providing the first schemes for position-based quantum cryptography. In 2005 he published with Lucien Hardy and Jonathan Barrett the first security proof of quantum key distribution based on the no-signalling principle. |
PaNie | PaNie is a 25 kDa protein produced by the root rot disease-causing pathogen Pythium aphanidermatum. It stands for Pythium aphanidermatum Necrosis inducing elicitor. PaNie (aka NLPPya) belongs to a family of elicitors named the Nep1-like proteins (NLPs), which cause necrosis when injected into the leaves of dicotyledonous plants. |
Embedded pavement flashing-light system | An embedded flashing-light system or an in-pavement flashing-light system is a type of device that is used at existing or new pedestrian crosswalks to warn drivers of oncoming pedestrian traffic. The device usually consists of LED lights that are embedded into the roadway alongside the crosswalk and are oriented to face oncoming traffic. When a pedestrian approaches the crosswalk, the system is activated and the LED lights begin to flash simultaneously. These lights are programmed to flash for a period of time that is sufficient for an average pedestrian to cross. |
Alkyl polyglycoside | Alkyl polyglycosides (APGs) are a class of non-ionic surfactants widely used in a variety of cosmetic, household, and industrial applications. Biodegradable and plant-derived from sugars, these surfactants are usually glucose derivatives, and fatty alcohols. The raw materials are typically starch and fat, and the final products are typically complex mixtures of compounds with different sugars comprising the hydrophilic end and alkyl groups of variable length comprising the hydrophobic end. When derived from glucose, they are known as alkyl polyglucosides. |
Factice | Factice is vulcanized unsaturated vegetable or animal oil, used as a processing aid and property modifier in rubber. |
Blackdamp | Blackdamp (also known as stythe or choke damp) is an asphyxiant, reducing the available oxygen content of air to a level incapable of sustaining human or animal life. It is not a single gas but a mixture of unbreathable gases left after oxygen is removed from the air and typically consists of nitrogen, carbon dioxide and water vapour. The term is etymologically and practically related to terms for other underground mine gases such as fire damp, white damp, stink damp, and afterdamp. |
Adelphi Genetics Forum | The Adelphi Genetics Forum is a non-profit learned society based in the United Kingdom. Its aims are "to promote the public understanding of human heredity and to facilitate informed debate about the ethical issues raised by advances in reproductive technology."It was founded by Sybil Gotto in 1907 as the Eugenics Education Society, with the aim of promoting the research and understanding of eugenics. Members came predominately from the professional class and included eminent scientists such as Francis Galton.: 145 The Society engaged in advocacy and research to further their eugenic goals, and members participated in activities such as lobbying Parliament, organizing lectures, and producing propaganda. It became the Eugenics Society in 1924: 144 (often referred to as the British Eugenics Society to distinguish it from others). From 1909 to 1968 it published The Eugenics Review, a scientific journal dedicated to eugenics.: 225 Membership reached its peak during the 1930s.The Society was renamed the Galton Institute in 1989. In 2021, it was renamed the Adelphi Genetics Forum. The organisation is currently based in Wandsworth, London. |
Beta (grape) | Beta is a winter-hardy variety of North American grape derived from a cross of the Vitis labrusca-based cultivar Concord and a selection of Vitis riparia, the wild riverbank grape, called Carver. It is an extremely cold-hardy grape that is self-fertile. This variety is grown successfully in Finland and was widely planted in Minnesota in the early 20th century. It ripens in late September in New York State. It bears dark, blue-black fruit that is used for jellies, fruit juices, etc. but rarely for wine. |
Digital automatic coupling | Digital automatic coupling (DAC) has been developed in the 2020s to replace the English Buffers and chain couplings, initially in Europe.
It resembles the Scharfenberg coupler with extra contacts to join electrical circuits (power, detection and control) and air hoses. |
Pecan oil | Pecan oil is an edible pressed oil extracted from the pecan nut. Pecan oil is neutral in flavor and takes on the flavor of whatever seasoning is being used with it. Pecan oil contains 9.5% saturated fat, which is less than in olive oil (13.5%), peanut oil (16.90%) or corn oil (12.70%). It is also used as a massage oil and in aromatherapy applications. |
Paper towel | A paper towel is an absorbent, disposable towel made from paper. In Britain, paper towels for kitchen use are also known as kitchen rolls, kitchen paper, or kitchen towels. For home use, paper towels are usually sold in a roll of perforated sheets, but some are sold in stacks of pre-cut and pre-folded layers for use in paper-towel dispensers. Unlike cloth towels, paper towels are disposable and intended to be used only once. Paper towels absorb water because they are loosely woven, which enables water to travel between the fibers, even against gravity (capillary effect). They have similar purposes to conventional towels, such as drying hands, wiping windows and other surfaces, dusting, and cleaning up spills. Paper towel dispensers are commonly used in toilet facilities shared by many people, as they are often considered more hygienic than hot-air hand dryers or shared cloth towels. |
Scribes (software) | Scribes is a lightweight free text editor for GNOME licensed under the terms of the GPL-2.0-or-later license. |
Buffer gas | A buffer gas is an inert or nonflammable gas. In the Earth's atmosphere, nitrogen acts as a buffer gas. A buffer gas adds pressure to a system and controls the speed of combustion with any oxygen present. Any inert gas such as helium, neon, or argon will serve as a buffer gas. |
Invalid carriage | Invalid carriages were usually single seater road vehicles, buggies, or self-propelled vehicles for disabled people. They pre-dated modern electric mobility scooters and, from the 1920s, were generally powered by small gasoline/petrol engines, although some were battery powered. They were usually designed without foot-operated controls.
The term "invalid carriage" persists in the United Kingdom in the regulation of mobility devices for disabled people, but excludes most of the more powerful, motorised types. |
Two-dimensional polymer | A two-dimensional polymer (2DP) is a sheet-like monomolecular macromolecule consisting of laterally connected repeat units with end groups along all edges. This recent definition of 2DP is based on Hermann Staudinger's polymer concept from the 1920s. According to this, covalent long chain molecules ("Makromoleküle") do exist and are composed of a sequence of linearly connected repeat units and end groups at both termini. |
Budesonide/formoterol | Budesonide/formoterol, sold under the brand name Symbicort among others, is a fixed-dose combination medication used in the management of asthma or chronic obstructive pulmonary disease (COPD). It contains budesonide, a steroid and formoterol, a long-acting β2-agonist (LABA). The product monograph does not support its use for sudden worsening or treatment of active bronchospasm. However, a 2020 review of the literature does support such use. It is used by breathing in the medication.Common (≥1/100 to <1/10) side effects include candidiasis, headache, tremor, palpitations, throat irritation, coughing, and dysphonia. Pneumonia is a common side effect in people with COPD, and other, less common side effects have been documented. There were concerns that the LABA component increases the risk of death in children with asthma, however these concerns were removed in 2017. Therefore, this combination is only recommended in those who are not controlled on an inhaled steroid alone. There is tentative evidence that typical doses of inhaled steroids and LABAs are safe in pregnancy. Both formoterol and budesonide are excreted in breast-milk.Budesonide/formoterol was approved for medical use in the United States in 2006. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the 61st most commonly prescribed medication in the United States, with more than 11 million prescriptions. |
Thermophotonics | Thermophotonics (often abbreviated as TPX) is a concept for generating usable power from heat which shares some features of thermophotovoltaic (TPV) power generation. Thermophotonics was first publicly proposed by solar photovoltaic researcher Martin Green in 2000. However, no TPX device is known to have been demonstrated to date, apparently because of the stringent requirement on the emitter efficiency. A TPX system consists of a light-emitting diode (LED) (though other types of emitters are conceivable), a photovoltaic (PV) cell, an optical coupling between the two, and an electronic control circuit. The LED is heated to a temperature higher than the PV temperature by an external heat source. If no power is applied to the LED, the system functions much like a very inefficient TPV system, but if a forward bias is applied at some fraction of the bandgap potential, an increased number of electron-hole pairs (EHPs) will be thermally excited to the bandgap energy. These EHPs can then recombine radiatively so that the LED emits light at a rate higher than the thermal radiation rate ("superthermal" emission). This light is then delivered to the cooler PV cell over the optical coupling and converted to electricity. |
Methylation | In the chemical sciences, methylation denotes the addition of a methyl group on a substrate, or the substitution of an atom (or group) by a methyl group. Methylation is a form of alkylation, with a methyl group replacing a hydrogen atom. These terms are commonly used in chemistry, biochemistry, soil science, and the biological sciences.
In biological systems, methylation is catalyzed by enzymes; such methylation can be involved in modification of heavy metals, regulation of gene expression, regulation of protein function, and RNA processing. In vitro methylation of tissue samples is also one method for reducing certain histological staining artifacts. The reverse of methylation is demethylation. |
Barakol | Barakol is a compound found in the plant Senna siamea, which is used in traditional herbal medicine. It has sedative and anxiolytic effects. There are contradictory pharmacological research findings concerning the toxicity of Cassia siamea and the active ingredient Barakol. One pharmacological study has shown an hepatoxic effect of Barakol while another study did not show any toxic effect at a daily dosage intake. Further research is needed to verify whether there are toxic effects of Barakol or not. |
Emotional aperture | Emotional aperture has been defined as the ability to perceive features of group emotions. This skill involves the perceptual ability to adjust one's focus from a single individual's emotional cues to the broader patterns of shared emotional cues that comprise the emotional composition of the collective. |
GPD Win | GPD Win is a Windows-based palmtop computer equipped with a keyboard and gaming controls. It is an x86-based device that runs Windows 10. It is capable of running any x86 Windows-based application that can run within the confines of the computer's hardware. First announced in October 2015, it was crowdfunded via Indiegogo and two other crowdfunding sites in Japan and China. The GPD Win was released in October 2016. |
Single particle analysis | Single particle analysis is a group of related computerized image processing techniques used to analyze images from transmission electron microscopy (TEM). These methods were developed to improve and extend the information obtainable from TEM images of particulate samples, typically proteins or other large biological entities such as viruses. Individual images of stained or unstained particles are very noisy, and so hard to interpret. Combining several digitized images of similar particles together gives an image with stronger and more easily interpretable features. An extension of this technique uses single particle methods to build up a three-dimensional reconstruction of the particle. Using cryo-electron microscopy it has become possible to generate reconstructions with sub-nanometer resolution and near-atomic resolution first in the case of highly symmetric viruses, and now in smaller, asymmetric proteins as well. Single particle analysis can also be performed by induced coupled plasma mass spectroscopy (ICP-MS). |
Solar eclipse of May 22, 2058 | A partial solar eclipse will occur on Wednesday, May 22, 2058. A solar eclipse occurs when the Moon passes between Earth and the Sun, thereby totally or partly obscuring the image of the Sun for a viewer on Earth. A partial solar eclipse occurs in the polar regions of the Earth when the center of the Moon's shadow misses the Earth. |
False pleasure | False pleasure may be a pleasure based on a false belief, or a pleasure compared with more real, or greater pleasures. Lacan maintained that philosophers should seek to "discern not true pleasures from false, for such a distinction is impossible to make, but the true and false goods that pleasure points to".When one is said to have experienced a false pleasure, it is distinct from feeling actual pleasure. Pleasure can be described as being false or true based on the content of where the pleasure comes from. When being faced with a situation where one holds a false belief that in turn makes them feel pleasure, this would be categorized as false pleasure. An example of this could be if someone gets pleasure from being in a happy relationship, yet they are unaware that the other person is cheating. Their pleasure then comes from a false belief. |
Geraniol | Geraniol is a monoterpenoid and an alcohol. It is the primary component of citronella oil and is a primary component of rose oil, palmarosa oil. It is a colorless oil, although commercial samples can appear yellow. It has low solubility in water, but it is soluble in common organic solvents. The functional group derived from geraniol (in essence, geraniol lacking the terminal −OH) is called geranyl. |
Drum memory | Drum memory was a magnetic data storage device invented by Gustav Tauschek in 1932 in Austria. Drums were widely used in the 1950s and into the 1960s as computer memory.
Many early computers, called drum computers or drum machines, used drum memory as the main working memory of the computer. Some drums were also used as secondary storage as for example various IBM drum storage drives.
Drums were displaced as primary computer memory by magnetic core memory, which offered a better balance of size, speed, cost, reliability and potential for further improvements. Drums in turn were replaced by hard disk drives for secondary storage, which were both less expensive and offered denser storage. The manufacturing of drums ceased in the 1970s. |
X.desktop | X.desktop was an early desktop environment graphical user interface built on the X Window System. It was developed and sold during the late 1980s and early 1990s by IXI Limited, a British software house based in Cambridge. Versions of X.desktop were available for over 30 different UNIX operating system platforms and it was licensed to various vendors, including IBM, Compaq, Locus Computing Corporation, BiiN and Acorn Computers, the latter licensing it in 1988 for its future workstation products.The "very first version" of X.desktop used Xlib, whereas version 1.3 (being the "first version seen by end users") used the Athena widget set. From version 2.0 ("the third major version") and onwards, the product was based on the Motif toolkit. This contrasted with one rival, Visix Software's Looking Glass, which continued to use its own proprietary graphical user interface toolkit instead of adopting Motif.X.desktop provided a user interface reminiscent of the Macintosh Finder, with the screen representing a desktop and with windows showing the contents of folders (or directories) in the filesystem. Such windows contained icons, each of which representing a file, folder or other filesystem object. Icons could be dragged outside windows (and thus onto the desktop itself) for convenient access in current and future login sessions. Double-clicking on icons initiated an open action on objects, with application programs typically being launched, although the nature of the action could be configured and multiple actions defined, such as the primary action for a text file being to open it in an editor, with a secondary action being to print the file. Icons could also be dropped onto other icons to initiate actions. For example, dropping a file icon onto a printer icon would initiate printing of the file. X.desktop was described as working "the way you'd expect a Unix/X application to work", seeking to represent the contents of the filesystem accurately.Regarded as being aimed at users wanting "an easy-to-use, Macintosh-style graphical representation of a desktop", the product was highly configurable, although configuration activities were mostly aimed at experienced users or administrators who would set up environments for end-users or customers, and a dedicated configuration guide was provided to support such activities. The software required a minimum of 2 MB to 4 MB of RAM to function. It could be purchased for $495 for a single-user licence, with bulk prices available, but was also bundled with workstations from numerous vendors. |
CalorieMate | CalorieMate (カロリーメイト karorīmeito) is a brand of nutritional energy bar and energy gel foods produced by Otsuka Pharmaceutical Co., in Japan. It was first released in 1983 debuting with a cheese flavored block. CalorieMate comes in several forms, including Block, Jelly, and Can. CalorieMate Block (カロリーメイト ブロック karorīmeito burokku) resembles a bar-shaped cookie (somewhat like a shortbread), sold in packs of either two or four. CalorieMate Jelly (カロリーメイト ゼリー karorīmeito zerī) is a gelatin sold in a pouch with a spout. CalorieMate Can (カロリーメイト 缶 karorīmeito kan) is a canned drink. |
Psychopathology | Psychopathology is the study of abnormal cognition, behaviour, and experiences which differs according to social norms and rests upon a number of constructs that are deemed to be the social norm at any particular era. |
Triple Peel | A Triple Peel (TP) is a standard manoeuvre in top-level games of association croquet.To peel a ball in croquet is to send a ball, other than the striker's ball, through its next hoop, thereby scoring a point for that ball. The ball in question is known as the "peelee". A prerequisite for a triple peel is that the peelee's next hoop is 4-back (so it has three hoops still to run). The striker, during a single turn, peels the peelee through its last three hoops and then pegs it out. Because a ball cannot be roqueted more than once without the striker's ball first running a hoop itself, the three peels are always performed in the course of making a break for the striker's ball, often a break that completes the full circuit of 12 hoops. |
Spring green | Spring green is a color that was traditionally considered to be on the yellow side of green, but in modern computer systems based on the RGB color model is halfway between cyan and green on the color wheel. The modern spring green, when plotted on the CIE chromaticity diagram, corresponds to a visual stimulus of about 505 nanometers on the visible spectrum. In HSV color space, the expression of which is known as the RGB color wheel, spring green has a hue of 150°. Spring green is one of the tertiary colors on the RGB color wheel, where it is the complementary color of rose. |
Spontaneous generation | Spontaneous generation is a superseded scientific theory that held that living creatures could arise from nonliving matter and that such processes were commonplace and regular. It was hypothesized that certain forms, such as fleas, could arise from inanimate matter such as dust, or that maggots could arise from dead flesh. The doctrine of spontaneous generation was coherently synthesized by the Greek philosopher and naturalist Aristotle, who compiled and expanded the work of earlier natural philosophers and the various ancient explanations for the appearance of organisms. Spontaneous generation was taken as scientific fact for two millennia. Though challenged in the 17th and 18th centuries by the experiments of the Italian biologists Francesco Redi and Lazzaro Spallanzani, it was not discredited until the work of the French chemist Louis Pasteur and the Irish physicist John Tyndall in the mid-19th century. |
Law of truly large numbers | The law of truly large numbers (a statistical adage), attributed to Persi Diaconis and Frederick Mosteller, states that with a large enough number of independent samples, any highly implausible (i.e. unlikely in any single sample, but with constant probability strictly greater than 0 in any sample) result is likely to be observed. Because we never find it notable when likely events occur, we highlight unlikely events and notice them more. The law is often used to falsify different pseudo-scientific claims; as such, it is sometimes criticized by fringe scientists. Similar theorem but bolder (for infinite numbers) is Infinite Monkey Theorem it shows that any finite pattern is possible to get, through infinite random process (but in this case there is skepticism about physical applicability of such arrangements because of finite nature of observable universe).The law is meant to make a statement about probabilities and statistical significance: in large enough masses of statistical data, even minuscule fluctuations attain statistical significance. Thus in truly large numbers of observations, it is paradoxically easy to find significant correlations, in large numbers, which still do not lead to causal theories (see: spurious correlation), and which by their collective number, might lead to obfuscation as well. |
Diacylglycerol oil | Diacylglycerol oil (DAG oil) is a cooking oil in which the ratio of triglycerides, also known as Triacylglycerols (TAGs), to diacylglycerols (DAGs) is shifted to contain mostly DAG, unlike conventional cooking oils, which are rich in TAGs. Vegetable DAG oil, for example, contains 80% DAG and is used as a 1:1 replacement for liquid vegetable oils in all applications. |
Collins glass | A collins glass is a glass tumbler which typically will contain 300 to 410 millilitres (10 to 14 US fl oz). It is commonly used to serve sparkling cocktails, especially long drinks like the Tom Collins or John Collins. Its cylindrical shape, narrower and taller than a highball glass, keeps the drink carbonated longer by reducing the surface area of the drink. |
Threshold potential | In electrophysiology, the threshold potential is the critical level to which a membrane potential must be depolarized to initiate an action potential. In neuroscience, threshold potentials are necessary to regulate and propagate signaling in both the central nervous system (CNS) and the peripheral nervous system (PNS). |
Scrubber (brush) | A scrubber (German: Schrubber), is a type of wide brush with a long shaft used for cleaning hard floors or surfaces. Unlike a broom, which has soft bristles to sweep dirt away, a scrubber has hard bristles for brushing. It may therefore be used wet, with water or cleaning fluids. Around the brush head there may also be a removable floorcloth or mop, either soaked in water for cleaning or dry for wiping dry. However, these days other cleaning implements tend to be used for such purposes. |
Church's thesis (constructive mathematics) | In constructive mathematics, Church's thesis CT is an axiom stating that all total functions are computable functions. |
Random hexamer | A random hexamer or random hexonucleotides are for various PCR applications such as rolling circle amplification to prime the DNA.
They are oligonucleotide sequences of 6 bases which are synthesised entirely randomly to give a numerous range of sequences that have the potential to anneal at many random points on a DNA sequence and act as a primer to commence first strand cDNA synthesis. |
MZF1 | Myeloid zinc finger 1 is a protein that in humans is encoded by the MZF1 gene. |
Adobe InCopy | Adobe InCopy is a professional word processor made by Adobe Inc. that integrates with Adobe InDesign. InCopy is used for general word processing, in contrast to InDesign, which is used to publish printed material, including newspapers and magazines. The software enables editors to write, edit, and design documents. The software includes standard word processing features such as spell check, track changes, and word count, and has various viewing modes that allow editors to visually inspect design elements — just as it looks to the designer working in Adobe InDesign.Version 3.0 of InCopy was included in the first Adobe Creative Suite in 2003, and later versions were included in versions of the Creative Suite up until version CS6. Since 2013 newer versions have been made available only through Adobe Creative Cloud. |
OR4K14 | Olfactory receptor 4K14 is a protein that in humans is encoded by the OR4K14 gene.Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. |
Fainting room | A fainting room was a private room, common in the Victorian era, which typically contained fainting couches. Such couches or sofas typically had an arm on one side only to permit easy access to a reclining position, similar to its cousin the Chaise longue, although the sofa style most typically featured a back at one end (usually the side with the arm) so that the resulting position was not purely supine. |
Remote Play | Remote Play is a feature of Sony video game consoles that allow the PlayStation 3, PlayStation 4 and PlayStation 5 to transmit video and audio output to another device; previously this could only be a PlayStation Portable or PlayStation Vita. In 2014, it was expanded to include the use of PlayStation TV, Xperia smartphones and tablets (Z2 and later), and PlayStation Now. In 2016, it was expanded to Microsoft Windows PCs and macOS. In 2019, support for Android and iOS devices was eventually added. Support for remote play of PlayStation 5 games to other devices was added in November 2020 just prior to the new console's launch. |
Estradiol | Estradiol (E2), also spelled oestradiol, is an estrogen steroid hormone and the major female sex hormone. It is involved in the regulation of the estrous and menstrual female reproductive cycles. Estradiol is responsible for the development of female secondary sexual characteristics such as the breasts, widening of the hips and a female-associated pattern of fat distribution. It is also important in the development and maintenance of female reproductive tissues such as the mammary glands, uterus and vagina during puberty, adulthood and pregnancy. It also has important effects in many other tissues including bone, fat, skin, liver, and the brain. |
Hemangiopericytoma | A hemangiopericytoma is a type of soft-tissue sarcoma that originates in the pericytes in the walls of capillaries. When inside the nervous system, although not strictly a meningioma tumor, it is a meningeal tumor with a special aggressive behavior. It was first characterized in 1942. |
Glass cloth | Glass cloth is a textile material woven from glass fiber yarn. |
Gerchberg–Saxton algorithm | The Gerchberg–Saxton (GS) algorithm is an iterative phase retrieval algorithm for retrieving the phase of a complex-valued wavefront from two intensity measurements acquired in two different planes. Typically, the two planes are the image plane and the far field (diffraction) plane, and the wavefront propagation between these two planes is given by the Fourier transform. The original paper by Gerchberg and Saxton considered image and diffraction pattern of a sample acquired in an electron microscope. |
Bitmap index | A bitmap index is a special kind of database index that uses bitmaps. |
Stylolite | Stylolites (Greek: stylos, pillar; lithos, stone) are serrated surfaces within a rock mass at which mineral material has been removed by pressure dissolution, in a deformation process that decreases the total volume of rock. Minerals which are insoluble in water, such as clays, pyrite and oxides, as well as insoluble organic matter, remain within the stylolites and make them visible. Sometimes host rocks contain no insoluble minerals, in which case stylolites can be recognized by change in texture of the rock. They occur most commonly in homogeneous rocks, carbonates, cherts, sandstones, but they can be found in certain igneous rocks and ice. Their size vary from microscopic contacts between two grains (microstylolites) to large structures up to 20 m in length and up to 10 m in amplitude in ice. Stylolites usually form parallel to bedding, because of overburden pressure, but they can be oblique or even perpendicular to bedding, as a result of tectonic activity. |
ELISA | The enzyme-linked immunosorbent assay (ELISA) (, ) is a commonly used analytical biochemistry assay, first described by Eva Engvall and Peter Perlmann in 1971. The assay uses a solid-phase type of enzyme immunoassay (EIA) to detect the presence of a ligand (commonly a protein) in a liquid sample using antibodies directed against the protein to be measured. ELISA has been used as a diagnostic tool in medicine, plant pathology, and biotechnology, as well as a quality control check in various industries. |
Register (air and heating) | A register is a grille with moving parts, capable of being opened and closed and the air flow directed, which is part of a building's heating, ventilation, and air conditioning (HVAC) system. The placement and size of registers is critical to HVAC efficiency. Register dampers are also important, and can serve a safety function. |
Vlog | A vlog (), also known as a video blog or video log, is a form of blog for which the medium is video. Vlog entries often combine embedded video (or a video link) with supporting text, images, and other metadata. Entries can be recorded in one take or cut into multiple parts. Vlog category is popular on the video-sharing platform YouTube. |
Uracil/thymine dehydrogenase | Uracil/thymine dehydrogenase (EC 1.17.99.4, uracil oxidase, uracil-thymine oxidase, uracil dehydrogenase) is an enzyme with systematic name uracil:acceptor oxidoreductase. This enzyme catalyses the following chemical reaction (1) uracil + H2O + acceptor ⇌ barbiturate + reduced acceptor (2) thymine + H2O + acceptor ⇌ 5-methylbarbiturate + reduced acceptorUracil/thymine dehydrogenase forms part of the oxidative pyrimidine-degrading pathway in some microorganisms. |
Stabs | stabs (sometimes written STABS) is a debugging data format for storing information about computer programs for use by symbolic and source-level debuggers. (The information is stored in symbol table strings; hence the name "stabs".) Cygnus Support attributes the invention of stabs to Peter Kessler for the Berkeley Pascal pdx debugger, however, he claims otherwise, stating stabs came with adb and sdb but could predate those. Mark Linton, who created pdx for his 1981 master's thesis and later developed it into dbx, states his doctoral adviser Michael L. Powell "contributed to the stabstrings design, especially to support Modula-2". |
Magic number (sports) | In certain sports, a magic number is a number used to indicate how close a front-running team is to clinching a division title and/or a playoff spot. It represents the total of additional wins by the front-running team or additional losses (or any combination thereof) by the rival teams after which it is mathematically impossible for the rival teams to capture the title in the remaining number of games (assuming some highly unlikely occurrence such as disqualification or expulsion from the competition or retroactive forfeiture of games does not occur). Magic numbers are generally confined to sports where each game results in a win or a loss, but not a tie. It could also be referred to as the "clinching number". |
Piano wire | Piano wire, or "music wire", is a specialized type of wire made for use in piano strings but also in other applications as springs. It is made from tempered high-carbon steel, also known as spring steel, which replaced iron as the material starting in 1834.
Piano wire has a very high tensile strength to cope with the heavy demands placed upon piano strings; accordingly, piano wire is also used for a number of other purposes, including springs, surgical uses, and in special effects. |
Enterocele | An enterocele is a protrusion of the small intestines and peritoneum into the vaginal canal.
It may be treated transvaginally or by laparoscopy.
An enterocele may also obstruct the rectum, leading to symptoms of obstructed defecation. Enteroceles can form after treatment for gynecological cancers. |
Powerhead (firearm) | A powerhead is a specialized firearm used underwater that is fired when in direct contact with the target. Powerheads are often used for spear fishing and against sharks or alligators for sport, defense, or to kill nuisance animals. The term powerhead refers to the firearm-like part of the device; when attached to a shaft to form a spear, it may be referred to as a bang stick or shark stick. The spear in question may be handheld or launchable from a spear gun. |
Ice II | Ice II is a rhombohedral crystalline form of ice with a highly ordered structure. It is formed from ice Ih by compressing it at a temperature of 198 K at 300 MPa or by decompressing ice V. When heated it undergoes transformation to ice III. Ordinary water ice is known as ice Ih, (in the Bridgman nomenclature). Different types of ice, from ice II to ice XIX, have been created in the laboratory at different temperatures and pressures. It is thought that the cores of icy moons like Jupiter's Ganymede may be made of ice II. |
Weyl integral | In mathematics, the Weyl integral (named after Hermann Weyl) is an operator defined, as an example of fractional calculus, on functions f on the unit circle having integral 0 and a Fourier series. In other words there is a Fourier series for f of the form ∑n=−∞∞aneinθ with a0 = 0.
Then the Weyl integral operator of order s is defined on Fourier series by ∑n=−∞∞(in)saneinθ where this is defined. Here s can take any real value, and for integer values k of s the series expansion is the expected k-th derivative, if k > 0, or (−k)th indefinite integral normalized by integration from θ = 0.
The condition a0 = 0 here plays the obvious role of excluding the need to consider division by zero. The definition is due to Hermann Weyl (1917). |
GRB 030329 | GRB 030329 was a gamma-ray burst (GRB) that was detected on 29 March 2003 at 11:37 UTC. A gamma-ray burst is a highly luminous flash associated with an explosion in a distant galaxy and producing gamma rays, the most energetic form of electromagnetic radiation, and often followed by a longer-lived "afterglow" emitted at longer wavelengths (X-ray, ultraviolet, optical, infrared, and radio). GRB 030329 was the first burst whose afterglow definitively exhibited characteristics of a supernova, confirming the existence of a relationship between the two phenomena. |
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