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Urban informatics
Urban informatics refers to the study of people creating, applying and using information and communication technology and data in the context of cities and urban environments. It sits at the conjunction of urban science, geomatics, and informatics, with an ultimate goal of creating more smart and sustainable cities. Various definitions are available, some provided in the Definitions section. Although first mentions of the term date back as early as 1987, urban informatics did not emerge as a notable field of research and practice until 2006 (see History section). Since then, the emergence and growing popularity of ubiquitous computing, open data and big data analytics, as well as smart cities, contributed to a surge in interest in urban informatics, not just from academics but also from industry and city governments seeking to explore and apply the possibilities and opportunities of urban informatics.
3M computer
3M was a goal first proposed in the early 1980s by Raj Reddy and his colleagues at Carnegie Mellon University (CMU) as a minimum specification for academic/technical workstations: at least a megabyte of memory, a megapixel display and a million instructions per second (MIPS) processing power. It was also often said that it should cost no more than a "megapenny" ($10,000).
UBC Okanagan Digital Microfluidics
The UBC Okanagan Digital Microfluidics Research Group is an interdisciplinary research group at University of British Columbia Okanagan that develops integrated devices for biochip applications. Lab-on-a-chip digital microfluidic devices are fabricated in digital architectures that merge micrometre-scale electrical circuitry with applications requiring dynamic fluid control, as voltage actuation signals from patterned electrodes are used to direct and actuate fluid flow within the chips. The structures are not application-specific. Fluid actuation signals for droplet mixing, splitting, and routing are set by the control software and can be reconfigured as needed and in real-time (unlike continuous-flow microfluidic structures incorporating micropumps, microvalves, and microchannels which are fabricated as permanent application-specific structures).
Branching order of bacterial phyla (Woese, 1987)
There are several models of the Branching order of bacterial phyla, one of these was proposed in 1987 paper by Carl Woese.The branching order proposed by Carl Woese was based on molecular phylogeny, which was considered revolutionary as all preceding models were based on discussions of morphology. (v. Monera). Several models have been proposed since and no consensus is reached at present as to the branching order of the major bacterial lineages.The gene used was the 16S ribosomal DNA.
Cell CANARY
Cell CANARY (Cellular Analysis and Notification of Antigen Risks and Yields) is a recent technology that uses genetically engineered B cells to identify pathogens. Existing pathogen detection technologies include the Integrated Biological Detection System and the Joint Chemical Agent Detector.
Calcium in biology
Calcium ions (Ca2+) contribute to the physiology and biochemistry of organisms' cells. They play an important role in signal transduction pathways, where they act as a second messenger, in neurotransmitter release from neurons, in contraction of all muscle cell types, and in fertilization. Many enzymes require calcium ions as a cofactor, including several of the coagulation factors. Extracellular calcium is also important for maintaining the potential difference across excitable cell membranes, as well as proper bone formation.
Flash cut
A flash cut, also called a flash cutover, is an immediate change in a complex system, with no phase-in period.
Veltuzumab
Veltuzumab is a monoclonal antibody (targeted at CD20) which is being investigated for the treatment of non-Hodgkin's lymphoma. As of December 2011, it is undergoing Phase I/II clinical trials. When used with milatuzumab it showed activity.This drug was developed by Immunomedics, Inc. and was originally known as IMMU-106.In August 2015 the US FDA granted it orphan drug status for immune thrombocytopenia (ITP). A phase II trial is planned to run for 5 years.
Combining Diacritical Marks for Symbols
Combining Diacritical Marks for Symbols is a Unicode block containing arrows, dots, enclosures, and overlays for modifying symbol characters. Its block name in Unicode 1.0 was simply Diacritical Marks for Symbols.
Art dealer
An art dealer is a person or company that buys and sells works of art, or acts as the intermediary between the buyers and sellers of art. An art dealer in contemporary art typically seeks out various artists to represent, and builds relationships with collectors and museums whose interests are likely to match the work of the represented artists. Some dealers are able to anticipate market trends, while some prominent dealers may be able to influence the taste of the market. Many dealers specialize in a particular style, period, or region. They often travel internationally, frequenting exhibitions, auctions, and artists' studios looking for good buys, little-known treasures, and exciting new works. When dealers buy works of art, they resell them either in their galleries or directly to collectors. Those who deal in contemporary art in particular usually exhibit artists' works in their own galleries. They will often take part in preparing the works of art to be revealed or processed.Art dealers' professional associations serve to set high standards for accreditation or membership and to support art exhibitions and shows.
Timeline of category theory and related mathematics
This is a timeline of category theory and related mathematics. Its scope ("related mathematics") is taken as: Categories of abstract algebraic structures including representation theory and universal algebra; Homological algebra; Homotopical algebra; Topology using categories, including algebraic topology, categorical topology, quantum topology, low-dimensional topology; Categorical logic and set theory in the categorical context such as algebraic set theory; Foundations of mathematics building on categories, for instance topos theory; Abstract geometry, including algebraic geometry, categorical noncommutative geometry, etc.
Conversational model
The conversational model of psychotherapy was devised by the English psychiatrist Robert Hobson, and developed by the Australian psychiatrist Russell Meares. Hobson listened to recordings of his own psychotherapeutic practice with more disturbed clients, and became aware of the ways in which a patient's self—their unique sense of personal being—can come alive and develop, or be destroyed, in the flux of the conversation in the consulting room.
Consed
Consed is a program for viewing, editing, and finishing DNA sequence assemblies. Originally developed for sequence assemblies created with phrap, recent versions also support other sequence assembly programs like Newbler.
Aerobiological engineering
Aerobiological engineering is the science of designing buildings and systems to control airborne pathogens and allergens in indoor environments. The most-common environments include commercial buildings, residences and hospitals. This field of study is important because controlled indoor climates generally tend to favor the survival and transmission of contagious human pathogens as well as certain kinds of fungi and bacteria.
Holmium(III) iodide
Holmium(III) iodide is an iodide of holmium, with the chemical formula of HoI3. It is used as a component of metal halide lamps.
Psychopia
Psychopia is a small press zine featuring reviews and articles on British comic books and small press comics and interviews with cartoonists. Unusually for comix zines it focussed almost entirely on British comics such as The Beano and The Dandy ignoring American superhero comics.
Burnside problem
The Burnside problem asks whether a finitely generated group in which every element has finite order must necessarily be a finite group. It was posed by William Burnside in 1902, making it one of the oldest questions in group theory and was influential in the development of combinatorial group theory. It is known to have a negative answer in general, as Evgeny Golod and Igor Shafarevich provided a counter-example in 1964. The problem has many refinements and variants (see bounded and restricted below) that differ in the additional conditions imposed on the orders of the group elements, some of which are still open questions.
Gestell
Gestell (or sometimes Ge-stell) is a German word used by twentieth-century German philosopher Martin Heidegger to describe what lies behind or beneath modern technology. Heidegger introduced the term in 1954 in The Question Concerning Technology, a text based on the lecture "The Framework" ("Das Gestell") first presented on December 1st 1949, in Bremen. It was derived from the root word stellen, which means "to put" or "to place" and combined with the German prefix Ge-, which denotes a form of "gathering" or "collection". The term encompasses all types of entities and orders them in a certain way.
Scaphoid fracture
A scaphoid fracture is a break of the scaphoid bone in the wrist. Symptoms generally includes pain at the base of the thumb which is worse with use of the hand. The anatomic snuffbox is generally tender and swelling may occur. Complications may include nonunion of the fracture, avascular necrosis of the proximal part of the bone, and arthritis.Scaphoid fractures are most commonly caused by a fall on an outstretched hand. Diagnosis is generally based on a combination of clinical examination and medical imaging. Some fractures may not be visible on plain X-rays. In such cases the affected area may be immobilised in a splint or cast and reviewed with repeat X-rays in two weeks, or alternatively an MRI or bone scan may be performed.The fracture may be preventable by using wrist guards during certain activities. In those in whom the fracture remains well aligned a cast is generally sufficient. If the fracture is displaced then surgery is generally recommended. Healing may take up to six months.It is the most commonly fractured carpal bone. Males are affected more often than females.
Telecommunications Management Network
The Telecommunications Management Network is a protocol model defined by ITU-T for managing open systems in a communications network. It is part of the ITU-T Recommendation series M.3000 and is based on the OSI management specifications in ITU-T Recommendation series X.700.
Separable partial differential equation
A separable partial differential equation is one that can be broken into a set of separate equations of lower dimensionality (fewer independent variables) by a method of separation of variables. This generally relies upon the problem having some special form or symmetry. In this way, the partial differential equation (PDE) can be solved by solving a set of simpler PDEs, or even ordinary differential equations (ODEs) if the problem can be broken down into one-dimensional equations. The most common form of separation of variables is simple separation of variables in which a solution is obtained by assuming a solution of the form given by a product of functions of each individual coordinate. There is a special form of separation of variables called R -separation of variables which is accomplished by writing the solution as a particular fixed function of the coordinates multiplied by a product of functions of each individual coordinate. Laplace's equation on Rn is an example of a partial differential equation which admits solutions through R -separation of variables; in the three-dimensional case this uses 6-sphere coordinates.
FORM (symbolic manipulation system)
FORM is a symbolic manipulation system. It reads text files containing definitions of mathematical expressions as well as statements that tell it how to manipulate these expressions. Its original author is Jos Vermaseren of Nikhef, the Dutch institute for subatomic physics. It is widely used in the theoretical particle physics community, but it is not restricted to applications in this specific field.
UFO sightings in Brazil
This is a list of alleged sightings of unidentified flying objects or UFOs in Brazil.
Mace-bearer
A mace-bearer, or macebearer, is a person who carries a mace, either a real weapon or ceremonial.
Solar eclipse of July 12, 2094
A partial solar eclipse will occur on July 12, 2094. A solar eclipse occurs when the Moon passes between Earth and the Sun, thereby totally or partly obscuring the image of the Sun for a viewer on Earth. A partial solar eclipse occurs in the polar regions of the Earth when the center of the Moon's shadow misses the Earth.
Suberedamine
Suberedamines are bio-active isolates of Suberea, a marine sponge. The compounds are brominated tyrosine dimer derivatives.
Mediastinum
The mediastinum (from Medieval Latin: mediastinus, lit. 'midway';PL: mediastina) is the central compartment of the thoracic cavity. Surrounded by loose connective tissue, it is an undelineated region that contains a group of structures within the thorax, namely the heart and its vessels, the esophagus, the trachea, the phrenic and cardiac nerves, the thoracic duct, the thymus and the lymph nodes of the central chest.
Astronomical spectroscopy
Astronomical spectroscopy is the study of astronomy using the techniques of spectroscopy to measure the spectrum of electromagnetic radiation, including visible light, ultraviolet, X-ray, infrared and radio waves that radiate from stars and other celestial objects. A stellar spectrum can reveal many properties of stars, such as their chemical composition, temperature, density, mass, distance and luminosity. Spectroscopy can show the velocity of motion towards or away from the observer by measuring the Doppler shift. Spectroscopy is also used to study the physical properties of many other types of celestial objects such as planets, nebulae, galaxies, and active galactic nuclei.
Chalcogel
A chalcogel or properly metal chalcogenide aerogel is an aerogel made from chalcogenides. Chalcogels preferentially absorb heavy metals, such as mercury, lead, and cadmium, from water. Sulfide chalcogels are also very good at desulfurization.Metal chalcogenide aerogels can be prepared from thiolysis or nanoparticle condensation and contain crystalline nanoparticles in the structure. The synthetic method can be extended to many thioanions, including tetrathiomolybdate-based chalcogels. Different metal ions have been used as linkers Co2+, Ni2+, Pb2+, Cd2+, Bi3+, Cr3+.When the gels are dried aerogels with high surface areas are obtained and the materials have multifunctional nature. For example, chalcogels are especially promising for gas separation. They were reported to exhibit high selectivity in CO2 and C2H6 over H2 and CH4 adsorption. The latter is relevant to exit gas stream composition of water gas shift reaction and steam reforming reactions (reactions widely used for H2 production). For example, separation of gas pairs such as CO2/H2, CO2/CH4, and CO2/N2 are key steps in precombustion capture of CO2, natural gas sweetening and postcombustion capture of CO2 processes leading ultimately at upgrading of the raw gas. The above mentioned conditioning makes the gas suitable for a number of applications in fuel cells.
Galactic plane
The galactic plane is the plane on which the majority of a disk-shaped galaxy's mass lies. The directions perpendicular to the galactic plane point to the galactic poles. In actual usage, the terms galactic plane and galactic poles usually refer specifically to the plane and poles of the Milky Way, in which Planet Earth is located.
Tolpiprazole
Tolpiprazole (INN, BAN) (developmental code name H-4170) is an anxiolytic drug of the phenylpiperazine group that was never marketed.
Lumican
Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12.
Shopping list
A shopping list is a list of items needed to be purchased by a shopper. Consumers often compile a shopping list of groceries to purchase on the next visit to the grocery store (a grocery list). There are surviving examples of Roman and Bible-era shopping lists.
Jersey (clothing)
Traditionally, a jersey is an item of knitted clothing, generally made of wool or cotton, with sleeves, worn as a pullover, as it does not open at the front, unlike a cardigan. It is usually close-fitting and machine knitted in contrast to a guernsey that is more often hand knit with a thicker yarn. The word is usually used interchangeably with sweater.Alternatively, the shirt worn by members of a sports team as part of the team uniform is also referred to as a jersey.
Dinonylnaphthylsulfonic acid
Dinonylnaphthylsulfonic acid (DINNSA) is an organic chemical, an aryl sulfonic acid. Its melting point is 259.5 °C and its boiling point is 600.4 °C. It has very low water solubility. It is a moderate skin irritant and a strong eye irritant. It has low volatility and vapor pressure and is stable above 100 °C. Dinonylnaphthylsulfonic acid is used as an additive in industrial lubricants, greases, cutting fluids, industrial coatings, and corrosion inhibitors. Its calcium and barium salts (CAS numbers 57855-77-3 and 25619-56-1, respectively) have generally the same use.
Apolipoprotein L1
Apolipoprotein L1 is a protein that in humans is encoded by the APOL1 gene. Two transcript variants encoding two different isoforms have been found for this gene.
ADP deaminase
In enzymology, an ADP deaminase (EC 3.5.4.7) is an enzyme that catalyzes the chemical reaction ADP + H2O ⇌ IDP + NH3Thus, the two substrates of this enzyme are ADP and H2O, whereas its two products are IDP and NH3. This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in cyclic amidines. The systematic name of this enzyme class is ADP aminohydrolase. Other names in common use include adenosine diphosphate deaminase, and adenosinepyrophosphate deaminase.
Videostream
Videostream was an application that enabled the streaming of video, music, and image files wirelessly to Google's Chromecast. Initially released as a standalone Google Chrome application, it was later transformed into a browser tab following Google's decision to cease support for the Chrome App Store. As of February 2021, the drag-and-drop feature, along with several other functionalities, were removed. Videostream was designed to streamline the process of video streaming to Chromecast. The application was capable of transcoding audio and video of incompatible files into a format supported by Chromecast. Several technology news outlets, including Engadget, Lifehacker and Tekzilla, gave positive feedback on the software's user-friendly interface and its ability to handle various video formats.
Symbiosis
Symbiosis (from Greek συμβίωσις, symbíōsis, "living together", from σύν, sýn, "together", and βίωσις, bíōsis, "living") is any type of a close and long-term biological interaction between two biological organisms of different species, termed symbionts, be it mutualistic, commensalistic, or parasitic. In 1879, Heinrich Anton de Bary defined it as "the living together of unlike organisms". The term is sometimes used in the more restricted sense of a mutually beneficial interaction in which both symbionts contribute to each other's support.Symbiosis can be obligatory, which means that one or more of the symbionts depend on each other for survival, or facultative (optional), when they can generally live independently.
Dead cat bounce
In finance, a dead cat bounce is a small, brief recovery in the price of a declining stock. Derived from the idea that "even a dead cat will bounce if it falls from a great height", the phrase is also popularly applied to any case where a subject experiences a brief resurgence during or following a severe decline. This may also be known as a "sucker rally".
Deadly Rooms of Death
Deadly Rooms of Death (DROD) is a computer puzzle game. It was created by Erik Hermansen in 1996 and has been regularly extended since then. The original version of the game published by Webfoot Technologies is no longer available. In 2000 the author reacquired the rights to DROD from Webfoot and released the source code; he continues the support and development as "Caravel DROD".
Dentition analysis
Dentition analyses are systems of tooth and jaw measurement used in orthodontics to understand arch space and predict any malocclusion (mal-alignment of the teeth and the bite). Example systems of dentition analysis are listed below.
Vapor-compression evaporation
Vapor-compression evaporation is the evaporation method by which a blower, compressor or jet ejector is used to compress, and thus, increase the pressure of the vapor produced. Since the pressure increase of the vapor also generates an increase in the condensation temperature, the same vapor can serve as the heating medium for its "mother" liquid or solution being concentrated, from which the vapor was generated to begin with. If no compression was provided, the vapor would be at the same temperature as the boiling liquid/solution, and no heat transfer could take place.
Pipe organ
The pipe organ is a musical instrument that produces sound by driving pressurised air (called wind) through the organ pipes selected from a keyboard. Because each pipe produces a single pitch, the pipes are provided in sets called ranks, each of which has a common timbre and volume throughout the keyboard compass. Most organs have many ranks of pipes of differing pitch, timbre, and volume that the player can employ singly or in combination through the use of controls called stops.
Alpha capture system
An alpha capture system is a computer system that enables investment banks and other organizations to submit "trading ideas" or "trade ideas" to clients in a written electronic format, for example TIM Group's TIM Ideas product or Bloomberg LP's Trade Ideas product.
Acetyllysine
Acetyllysine (or acetylated lysine) is an acetyl-derivative of the amino acid lysine. There are multiple forms of acetyllysine - this article refers to N-ε-acetyl-L-lysine. The other form is N-α-acetyl-L-lysine. In proteins, the acetylation of lysine residues is an important mechanism of epigenetics. It functions by regulating the binding of histones to DNA in nucleosomes and thereby controlling the expression of genes on that DNA. Non-histone proteins are acetylated as well. Unlike the functionally similar methyllysine, acetyllysine does not carry a positive charge on its side chain. Histone acetyltransferases (HATs) catalyze the addition of acetyl groups from acetyl-CoA onto certain lysine residues of histones and non-histone proteins. Histone deacetylases (HDACs) catalyze the removal of acetyl groups from acetylated lysines. Acetyllysine can be synthesized from lysine by the selective acetylation of the terminal amine group.
Lateral masking
Lateral masking is a problem for the human visual perception of identical or similar entities in close proximity. This can be illustrated by the difficulty of counting the vertical bars of a barcode. In linguistics lateral masking refers to the interference a letter has on its neighbor. This is a problem readers encounter when reading a word. The identity of a letter in the middle of a word is obscured by the presence of its neighboring letters. Lateral masking may also be a problem in orthography design. A readable orthography will avoid situations in which a reader is faced with severe lateral masking.
DNAI1
Dynein axonemal intermediate chain 1 is a protein that in humans is encoded by the DNAI1 gene.The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. This gene encodes an intermediate chain dynein, belonging to the large family of motor proteins. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia (PCD) and Kartagener syndrome. The DNAI1 gene is involved in the development of proper respiratory function, motility of spermatozoa, and asymmetrical organization of the viscera during embryogenesis. This gene affects these three very different aspects of development because all three are dependent on proper cilia function. DNAI1 codes for the development of cilia ultrastructure in the upper and lower respiratory tracts, spermatozoa flagellae, and nodal cilia (cilia of the primitive node). DNAI1 specifically encodes for an intermediate chain of the outer dynein arm. Each dynein arm of the ciliary axoneme has an inner and outer dynein arm. A mutation in DNAI1 can lead to defective ciliary beating. A DNAI1 gene mutation accounts for 4-10% of all cases of primary ciliary dyskensia (PCD). The most frequent structural defect in cilia of PCD patients are abnormal dynein arms. A common mutation of DNAI1 leading to PCD is a hot-spot mutation in intron 1 of the gene. Mutations in coding or splicing are only found in 10% of PCD cases.
Amdahl's law
In computer architecture, Amdahl's law (or Amdahl's argument) is a formula which gives the theoretical speedup in latency of the execution of a task at fixed workload that can be expected of a system whose resources are improved. It states that "the overall performance improvement gained by optimizing a single part of a system is limited by the fraction of time that the improved part is actually used". It is named after computer scientist Gene Amdahl, and was presented at the American Federation of Information Processing Societies (AFIPS) Spring Joint Computer Conference in 1967.
Provel cheese
Provel () is a white processed cheese product particularly popular in St. Louis cuisine, that is a combination of cheddar, Swiss, and provolone cheeses. Provel has a low melting point, and therefore has a gooey and almost buttery texture at room temperature. It is the traditional topping for St. Louis-style pizza. It is also often used in the preparation of cheese soup and served on salads, chicken, and the Gerber sandwich. Some restaurants use Provel for their pasta dishes with white sauce instead of the customary fresh Italian cheese and cream.
Bolt snap
A bolt snap is a type of snap hook with a manually operated bolt action slide gate of medium security used to clip a light load to a ring, eye, loop or bight to temporarily secure or suspend an object. They are used for a wide variety of applications including dog leads and for clipping scuba equipment to the diving harness. A similar but more secure device used to attach sails to a stay is known as a piston hank. It differs from a snap shackle in that the load is not carried by the gate. The bolt snap must be actively operated by the user to clip or unclip, and is not easily snagged or unintentionally clipped or unclipped by pressing or bumping against the surroundings.The most common type has a single snap hook at one end and a swivel ring at the other, but double ended bolt snaps and single ended snaps with a swivel shackle are also available. There are a few variations on the style of the hook, gate opening and swivel style. The characteristic element of the bolt snap is the bolt action gate. This is a spring loaded rod which slides longitudinally inside the body of the clip against a compression spring to open the gate of the hook, and returns to rest against the tip of the hook by the action of the spring when released. Bolt snaps are not generally load rated, and are not used to suspend heavy loads. Most applications are in the load range where the user can lift the object to be clipped, or can hold the load manually.
Bass–Quillen conjecture
In mathematics, the Bass–Quillen conjecture relates vector bundles over a regular Noetherian ring A and over the polynomial ring A[t1,…,tn] . The conjecture is named for Hyman Bass and Daniel Quillen, who formulated the conjecture.
Pygame
Pygame is a cross-platform set of Python modules designed for writing video games. It includes computer graphics and sound libraries designed to be used with the Python programming language.
Crateology
Crateology was the 'science' of identifying the contents of Soviet shipments to the Island of Cuba carried out by the Central Intelligence Agency during the Cuban Missile Crisis.Crateology has declined as a discipline in recent years due to globalisation and the decline in the usage of custom made wooden crates in favour of standard metal shipping containers. Though making the world intra-connected and smaller, globalisation has resulted in the loss of not merely a science, but a 'beautiful art form'.
Non-synchronous transmission
A non-synchronous transmission, also called a crash gearbox, is a form of manual transmission based on gears that do not use synchronizing mechanisms. They require the driver to manually synchronize the transmission's input speed (engine RPM) and output speed (driveshaft speed). Non-synchronous transmissions are found primarily in various types of industrial machinery; such as tractors and semi-tractors. Non-synchronous manual transmissions are also found on motorcycles, in the form of constant-mesh sequential manual transmissions. Prior to the 1950s and 1960s, most cars used constant-mesh (and also sliding-mesh) but non-synchronous transmissions.
Central simple algebra
In ring theory and related areas of mathematics a central simple algebra (CSA) over a field K is a finite-dimensional associative K-algebra A which is simple, and for which the center is exactly K. (Note that not every simple algebra is a central simple algebra over its center: for instance, if K is a field of characteristic 0, then the Weyl algebra K[X,∂X] is a simple algebra with center K, but is not a central simple algebra over K as it has infinite dimension as a K-module.) For example, the complex numbers C form a CSA over themselves, but not over the real numbers R (the center of C is all of C, not just R). The quaternions H form a 4-dimensional CSA over R, and in fact represent the only non-trivial element of the Brauer group of the reals (see below).
Water damage
Water damage describes various possible losses caused by water intruding where it will enable attack of a material or system by destructive processes such as rotting of wood, mold growth, bacteria growth, rusting of steel, swelling of composite woods, de-laminating of materials such as plywood, short-circuiting of electrical devices, etc. The damage may be imperceptibly slow and minor such as water spots that could eventually mar a surface, or it may be instantaneous and catastrophic such as burst pipes and flooding. However fast it occurs, water damage is a major contributor to loss of property.
History of Biology (video game)
History of Biology is a browser-based scavenger hunt–style educational game that was created by Spongelab Interactive. It is designed to teach high school students and general interest groups about the history of biology.
RAB35
Ras-related protein Rab-35 is a protein that in humans is encoded by the RAB35 gene. This GTPase participates in the traffic of recycling endosomes toward the plasma membrane,
Intravascular lymphomas
Intravascular lymphomas (IVL) are rare cancers in which malignant lymphocytes proliferate and accumulate within blood vessels. Almost all other types of lymphoma involve the proliferation and accumulation of malignant lymphocytes in lymph nodes, other parts of the lymphatic system (e.g. the spleen), and various non-lymphatic organs (e.g. bone marrow and liver) but not in blood vessels.IVL fall into three different forms based on the type of lymphocyte causing the disease. Intravascular large B-cell lymphoma (IVBCL), which constitutes ~90% of all IVL, is a lymphoma of malignant B-cell lymphocytes as classified by the World Health Organization, 2016. The remaining IVL types, which have not yet been formally classified by the World Health Organization, are defined based mainly on case reports; these IVL are 1) intravascular NK-cell lymphoma (IVNKL) in which the malignant cells are a type of T cell lymphocyte termed natural killer cells (NK-cells) and 2) intravascular T-cell lymphoma (IVTL) in which the neoplastic cells are primarily, if not exclusively, a type of t-cell termed cytotoxic T-cells. Because of their similarities and extreme rarities, IVL lymphomas caused by NK-cells and cytotoxic T-cells are often grouped together under the term intravascular NK/T cell lymphomas (IVNK/TL). The malignant cells in IVNK/TL are typically infected with the Epstein–Barr virus suggesting that these lymphomas are examples of the Epstein-Barr virus-associated lymphoproliferative diseases. Since infection with this virus is rarely seen in IVBCL, this form of IVL is not typically regarded as one of the Epstein-Barr virus-associated lymphoproliferative diseases.Intravascular large B-cell and intravascular NK/T cell IVL are typically very aggressive lymphomas that afflict middle-aged and elderly adults. At the time of diagnosis, they accumulate within small-sized and medium-sized but not large-sized blood vessels of the skin, central nervous system, and, less frequently. virtually any other organ system. Unlike most lymphomas, however, they generally do not accumulate or infiltrate lymph nodes. All of the IVL are frequently associated with systemic B symptoms such as fever and weight loss, as well as symptoms related to the other organs in which they accumulate in blood vessels, constrict blood flow, and thereby cause severe damage due to infarction, i.e. damage due to the loss of blood flow.Historically, most cases of the intravascular lymphomas responded very poorly to standard chemotherapy regimens that were used to treat other types of the B-cell lymphomas. With few exceptions, these intravascular lymphomas progressed very rapidly. More recently, however, the addition to these chemotherapy regimens of the immunotherapy agents, Rituximab, which acts to kill B-cells, has greatly improved their effectiveness and thereby the prognosis of the most common form of these diseases, the intravascular B-cell lymphomas. Unfortunately, no such agent that is directed against NK-cells or cytotoxic T-cells has yet been reported to be useful in treating these two types of the intravascular B-cell lymphomas.
Node (UML)
A node in the Unified Modeling Language (UML) is a computational resource upon which UML artifacts may be deployed for execution. There are two types of nodes: device nodes and execution environments. A device represents hardware devices: a physical computational resource with processing capability upon which UML artifacts may be deployed for execution. Devices may be complex (i.e., they may consist of other devices).
Clinical pharmaceutical chemistry
Clinical pharmaceutical chemistry is a specialty branch of chemical sciences, which consists of medicinal chemistry with additional training in clinical aspects of translational sciences and medicine. Typically this involves similar principal training as in general medicine, where inspection of and interaction with the patients are a vital part of the training.Typically students in clinical pharmaceutical chemistry use the same curriculum as medical students, but specialize in medicinal and organic chemistry after and during the theoretical/early clinical studies. In clinical pharmaceutical chemistry the aim is to understand biological transformations and processes associated with chemical entities inside the human body, and how those processes can be influenced with changes in chemical structures. The aim of clinical pharmaceutical chemistry is in addition to manage and manipulate clinical effects of different chemical structures, as well as to manage phenomena recognized in first-in-human studies. Typically clinical pharmaceutical chemistry has an important role in discovery, design and manipulation of new drug entities, and is vital especially in early clinical studies (such as Phase I studies).
Fire blanket
A fire blanket is a safety device designed to extinguish incipient (starting) fires. It consists of a sheet of a fire retardant material that is placed over a fire in order to smother it.
Current meter
A current meter is an oceanographic device for flow measurement by mechanical, tilt, acoustical or electrical means.
OR2A12
Olfactory receptor 2A12 is a protein that in humans is encoded by the OR2A12 gene.Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
Aurora's Whole Realms Catalog
Aurora's Whole Realms Catalog is an accessory for the Dungeons & Dragons fantasy role-playing game, published for the Forgotten Realms setting.
8-simplex
In geometry, an 8-simplex is a self-dual regular 8-polytope. It has 9 vertices, 36 edges, 84 triangle faces, 126 tetrahedral cells, 126 5-cell 4-faces, 84 5-simplex 5-faces, 36 6-simplex 6-faces, and 9 7-simplex 7-faces. Its dihedral angle is cos−1(1/8), or approximately 82.82°. It can also be called an enneazetton, or ennea-8-tope, as a 9-facetted polytope in eight-dimensions. The name enneazetton is derived from ennea for nine facets in Greek and -zetta for having seven-dimensional facets, and -on.
Utility system
In video game AI, a utility system, or utility AI, is a simple but effective way to model behaviors for non-player characters. Using numbers, formulas, and scores to rate the relative benefit of possible actions, one can assign utilities to each action. A behavior can then be selected based on which one scores the highest "utility" or by using those scores to seed the probability distribution for a weighted random selection. The result is that the character is selecting the "best" behavior for the given situation at the moment based on how those behaviors are defined mathematically.
Unraid
Unraid is a proprietary Linux-based operating system designed to run on home media server setups that operates as a network-attached storage device, application server, and virtualization host. Unraid is proprietary software developed and maintained by Lime Technology, Inc. Users of the software are encouraged to write and use plugins and Docker applications to extend the functionality of their systems.
Matrix decoder
Matrix decoding is an audio technology where a small number of discrete audio channels (e.g., 2) are decoded into a larger number of channels on play back (e.g., 5). The channels are generally, but not always, arranged for transmission or recording by an encoder, and decoded for playback by a decoder. The function is to allow multichannel audio, such as quadraphonic sound or surround sound to be encoded in a stereo signal, and thus played back as stereo on stereo equipment, and as surround on surround equipment – this is "compatible" multichannel audio.
LOXL2
Lysyl oxidase homolog 2 is an enzyme that in humans is encoded by the LOXL2 gene.
W Corvi
W Corvi is an eclipsing binary star system in the constellation Corvus, ranging from apparent magnitude 11.16 to 12.5 over 9 hours. Its period has increased by 1/4 second over a century. It is an unusual system in that its two stars are very close to each other yet have different surface temperatures and hence thermal transfer is not taking place as expected.
Getsuku
Getsuku (月9, getsuku, sometimes further shortened to gekku) is a Japanese abbreviation for Getsuyō kuji (月曜9時, Monday at 9 pm). This is traditionally the time when the most popular TV dramas air in Japan.
Cannabis in Benin
Cannabis in Benin is illegal. The country is not a major drug producer or consumer, but increasingly serves as a transshipment point for drugs produced elsewhere. Cannabis is the only drug produced locally in Benin, though mostly on a small scale.
SPEN
Msx2-interacting protein is a protein that in humans is encoded by the SPEN gene.This gene encodes a hormone inducible transcriptional repressor. Repression of transcription by this gene product can occur through interactions with other repressors, by the recruitment of proteins involved in histone deacetylation, or through sequestration of transcriptional activators. The product of this gene contains a carboxy-terminal domain that permits binding to other corepressor proteins. This domain also permits interaction with members of the NuRD complex, a nucleosome remodeling protein complex that contains deacetylase activity. In addition, this repressor contains several RNA recognition motifs that confer binding to a steroid receptor RNA coactivator; this binding can modulate the activity of both liganded and nonliganded steroid receptors.
Hydrophobic effect
The hydrophobic effect is the observed tendency of nonpolar substances to aggregate in an aqueous solution and exclude water molecules. The word hydrophobic literally means "water-fearing", and it describes the segregation of water and nonpolar substances, which maximizes hydrogen bonding between molecules of water and minimizes the area of contact between water and nonpolar molecules. In terms of thermodynamics, the hydrophobic effect is the free energy change of water surrounding a solute. A positive free energy change of the surrounding solvent indicates hydrophobicity, whereas a negative free energy change implies hydrophilicity.
MIMOS II
MIMOS II is the miniaturised Mössbauer spectrometer, developed by Dr. Göstar Klingelhöfer at the Johannes Gutenberg University in Mainz, Germany, that is used on the Mars Exploration Rovers Spirit and Opportunity for close-up investigations on the Martian surface of the mineralogy of iron-bearing rocks and soils.MIMOS II uses a Cobalt-57 gamma ray source of about 300 mCi at launch which gave a 6-12 hr time for acquisition of a standard MB spectrum during the primary mission on Mars, depending on total Fe content and which Fe-bearing phases are present. Cobalt-57 has a half-life of only 271.8 days (hence the extended measuring times now on Mars after over a decade).
International Academy of Medical and Biological Engineering
The International Academy of Medical and Biological Engineering (IAMBE) is a non-profit society of distinguished scholars engaged in medical and biological engineering research to further the field of biomedical engineering or bioengineering. The academy is composed of Fellows who have made significant contributions to and played leadership roles in the field of medical and biological engineering. The academy is affiliated with the International Federation for Medical and Biological Engineering (IFMBE), an international organization consisting of more than 60 national and transnational societies of biomedical engineering, representing over 120,000 members.
Wide chord
Wide chord fan refers to the fan blades on a modern turbofan jet engine having a ducted fan with a specific blade geometry - In layman's terms, they would be described as having wider blades than other jet engines. The technology was pioneered by Geoff Wilde at Rolls-Royce in the 1970s.
Magneto-optic effect
A magneto-optic effect is any one of a number of phenomena in which an electromagnetic wave propagates through a medium that has been altered by the presence of a quasistatic magnetic field. In such a medium, which is also called gyrotropic or gyromagnetic, left- and right-rotating elliptical polarizations can propagate at different speeds, leading to a number of important phenomena. When light is transmitted through a layer of magneto-optic material, the result is called the Faraday effect: the plane of polarization can be rotated, forming a Faraday rotator. The results of reflection from a magneto-optic material are known as the magneto-optic Kerr effect (not to be confused with the nonlinear Kerr effect).
Swedish interactive thresholding algorithm
The Swedish interactive thresholding algorithm, usually referred to as SITA, is a method to test for visual field loss, usually in glaucoma testing or monitoring. It is combined with a visual field test such as standard automated perimetry (SAP) or short wavelength automated perimetry (SWAP) to determine visual fields in a more efficient manner.
Q code
The Q-code is a standardised collection of three-letter codes that each start with the letter "Q". It is an operating signal initially developed for commercial radiotelegraph communication and later adopted by other radio services, especially amateur radio. To distinguish the use of a Q-code transmitted as a question from the same Q-code transmitted as a statement, operators either prefixed it with the military network question marker "INT" (dit dit dah dit dah) or suffixed it with the standard Morse question mark UD (dit dit dah dah dit dit).
Type 2 connector
The IEC 62196 Type 2 connector (often referred to as Mennekes for the company that designed it) is used for charging electric vehicles, mainly within Europe, as it was declared standard by the EU. Based on widespread red IEC 60309 three phase plugs with five pins, which come in different diameters according to maximum current (most common are 16 A and 32 A), a single size was selected, as maximum possible power will be communicated to the car via two additional communication pins and by a simple resistor coding within the cable. The onboard charger inside the car has to limit the current accordingly. The connector is circular in shape, with a flattened top edge; the original design specification carried an output electric power of 3–50 kW for charging battery electric vehicles using single-phase (230V) or three-phase (400V) alternating current (AC), with a typical maximum of 32 A 7.2 kW using single-phase AC and 22 kW with three-phase AC in common practice. The plugs have openings on the sides that allow both the car and the charger to lock the plug automatically to prevent unwanted interruption of charging, or theft of the cable.
Language exchange
Language exchange is a method of language learning based on mutual language practicing by learning partners who are speakers of different languages. This is usually done by two native speakers teaching each other their native language. Language exchange is different from other Language learning methods as there is usually no set syllabus or activities. Language exchange is sometimes called Tandem language learning.In modern contexts, "language exchange" most often refers to the mutual teaching of partners' first languages. Language exchanges are generally considered helpful for developing language proficiency, especially in speaking fluency and listening comprehension. Language exchanges that take place through writing or text chats also improve reading comprehension and writing ability. The aim of language exchange is to develop and increase language knowledge and intercultural skills. This is usually done through social interaction with the native speaker. Given that language exchanges generally take place between native speakers of different languages, there is also the side benefit of improving cross-cultural communication.
Germabenzene
Germabenzene (C5H6Ge) is the parent representative of a group of chemical compounds containing in their molecular structure a benzene ring with a carbon atom replaced by a germanium atom. Germabenzene itself has been studied theoretically, and synthesized with a bulky 2,4,6-tris[bis(trimethylsilyl)methyl]phenyl or Tbt group. Also, stable naphthalene derivatives do exist in the laboratory such as the 2-germanaphthalene-containing substance represented below. The germanium to carbon bond in this compound is shielded from potential reactants by a Tbt group. This compound is aromatic just as the other carbon group representatives silabenzene and stannabenzene.
Erythrocyte deformability
Erythrocyte deformability refers to the ability of erythrocytes (red blood cells, RBC) to change shape under a given level of applied stress, without hemolysing (rupturing). This is an important property because erythrocytes must change their shape extensively under the influence of mechanical forces in fluid flow or while passing through microcirculation. The extent and geometry of this shape change can be affected by the mechanical properties of the erythrocytes, the magnitude of the applied forces, and the orientation of erythrocytes with the applied forces. Deformability is an intrinsic cellular property of erythrocytes determined by geometric and material properties of the cell membrane, although as with many measurable properties the ambient conditions may also be relevant factors in any given measurement. No other cells of mammalian organisms have deformability comparable with erythrocytes; furthermore, non-mammalian erythrocytes are not deformable to an extent comparable with mammalian erythrocytes. In human RBC there are structural support that aids resilience in RBC which include the cytoskeleton- actin and spectrin that are held together by ankyrin.
ECC memory
Error correction code memory (ECC memory) is a type of computer data storage that uses an error correction code (ECC) to detect and correct n-bit data corruption which occurs in memory. ECC memory is used in most computers where data corruption cannot be tolerated, like industrial control applications, critical databases, and infrastructural memory caches.
Scoopula
Scoopula is a brand name of a spatula-like scoop utensil used primarily in experimental laboratories to transfer solids: to a weighing paper for weighing, to a cover slip to measure melting point, or a graduated cylinder, or to a watch glass from a flask or beaker through scraping. "Scoopula" is a registered trademark owned by Thermo Fisher Scientific. They are very often made of metal.
Wet T-shirt contest
A wet T-shirt contest is a competition involving exhibitionism, typically featuring young women contestants at a nightclub, bar, or resort. Wet T-shirt contestants generally wear thin white or light-colored T-shirts without bras, bikini tops, or other garments beneath. Water (often ice water) is then sprayed or poured onto the participants' chests, causing their T-shirts to turn translucent and cling to their breasts. The comparatively rarer male equivalent is the wet boxer contest, sometimes held at gay bars.Contestants may take turns dancing or posing before the audience, with the outcome decided either by crowd reaction or by judges' vote. In racier contests, participants may tear or crop their T-shirts to expose their midriffs, cleavage, or the undersides of their breasts. Depending on local laws, participants may be allowed to remove their T-shirts or strip completely naked during their performance.
Organoid
An organoid is a miniaturized and simplified version of an organ produced in vitro in three dimensions that mimics the key functional, structural and biological complexity of that organ. They are derived from one or a few cells from a tissue, embryonic stem cells or induced pluripotent stem cells, which can self-organize in three-dimensional culture owing to their self-renewal and differentiation capacities. The technique for growing organoids has rapidly improved since the early 2010s, and The Scientist names it as one of the biggest scientific advancements of 2013. Scientists and engineers use organoids to study development and diseases in the laboratory and industry for drug discovery and development, personalized diagnostics and medicine, gene and cell therapies, tissue engineering and regenerative medicine.
Dynamic Chiropractic
Dynamic Chiropractic is a magazine for chiropractors that is indexed by CINAHL. The publisher is MPA Media. A Canadian version exists with modified content. The Canadian version has a readership of 6000, while the American version has a circulation of over 60,000.
Ad Lib (typeface)
Ad Lib is a decorative typeface that was designed in 1961 by Freeman Craw for American Type Founders. It was extremely popular from the early- to mid-1960s, and is often used today to evoke that era.The typeface is known for its square counters a-la the 60's. A SoftMaker version of this font has straighter edges for glyphs.
S scale
S scale (or S gauge) is a model railroad scale modeled at 1:64 scale, S scale track gauge (space between the rails) is 22.48 mm (0.885 in). S gauge trains are manufactured in both DC and AC powered varieties. S gauge is not to be confused with toy train standard gauge, a large-scale standard for toy trains in the early part of the 20th century.
Forpet
A forpet, lippie or lippy was a Scottish unit of dry measure equal to a quarter or fourth-part of a peck. A lippie was so called because a leap was a traditional name for a basket in Scotland.
Paronychia
Paronychia is an inflammation of the skin around the nail, which can occur suddenly, when it is usually due to the bacterium Staphylococcus aureus, or gradually when it is commonly caused by the fungus Candida albicans. The term is from Greek: παρωνυχία from para 'around', onyx 'nail', and the abstract noun suffix -ia.Risk factors include repeatedly washing hands and trauma to the cuticle such as may occur from repeated nail biting or hangnails.
Non-binary gender
Non-binary and genderqueer are umbrella terms for gender identities that are not solely male or female (identities outside the gender binary). Non-binary identities fall under the transgender umbrella, since non-binary people typically identify with a gender that is different from their sex, though some non-binary people do not consider themselves transgender.Non-binary people may identify as an intermediate or separate third gender, identify with more than one gender, no gender, or have a fluctuating gender identity. Gender identity is separate from sexual or romantic orientation: non-binary people have various sexual orientations. Being non-binary is also not the same as being intersex; most intersex people identify as either male or female.Non-binary people as a group vary in their gender expressions, and some may reject gender identity altogether. Some non-binary people are medically treated for gender dysphoria with surgery or hormones, as trans men and trans women often are.
Looking-glass self
The term looking-glass self was created by American sociologist Charles Horton Cooley in 1902, and introduced into his work Human Nature and the Social Order. It is described as our reflection of how we think we appear to others. Cooley takes into account three steps when using "the looking glass self". Step one is how one imagines one looks to other people. Step two is how one imagines the judgment of others based on how one thinks they view them. Step three is how one thinks of how the person views them based on their previous judgments.According to Lisa McIntyre's The Practical Skeptic: Core Concepts in Sociology, the concept of the looking-glass self expresses the tendency for one to understand oneself through the perception which others may hold of them.
Fishing rod
A fishing rod is a long, thin rod used by anglers to catch fish by manipulating a line ending in a hook (formerly known as an angle, hence the term "angling"). At its most basic form, a fishing rod is a straight rigid stick/pole with a line attached to one end (as seen in traditional Tenkara fishing); however, modern rods are usually elastic and generally have the line stored in a reel mounted at the rod handle, which is hand-cranked and controls the line retrieval, as well as numerous line-restricting rings (also known as line guides) that distribute bending stress along the rod and help dampening down/prevent line whipping and entanglement. To better entice fish, baits or lures are dressed onto the one or more hooks attached to the line, and a bite indicator is used, some of which (e.g. quiver tip) might be incorporated as part of the rod itself.
Immunosignature
Immunosignaturing is a medical diagnostic test which uses arrays of random-sequence peptides to associate antibodies in a blood sample with a disease.
Ashtekar variables
In the ADM formulation of general relativity, spacetime is split into spatial slices and a time axis. The basic variables are taken to be the induced metric qab(x) on the spatial slice and the metric's conjugate momentum Kab(x) , which is related to the extrinsic curvature and is a measure of how the induced metric evolves in time. These are the metric canonical coordinates.