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823c2665_bulary_d_Flashcards___Cram_com__1
[2] teachiings in general; partical principle (religious, legal) taught [1]
doctrine
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] unable to compromise about points of doctrine; dogmatic; unyielding. Weng had hoped that the student led democracy movement might bring about a change in china, but the repressive response of the doctrinaire hard liners crusihed his dreams of democracy [1]
doctrinaire
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] program as for trial; book where such entries are made. The case of Smith V. Hones was entered in the docket for July 15. [1]
docket
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] obedient; easily managed. As docile as he seems today, that old lion was once a ferocious, snarling beast. Docility. N [1]
docile
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] reveal. No lover of gossip, Charlotte would never divulge anything that a friend told her in confidence [1]
divulge
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] perceive intuitvely; foresee the future. Nothing infuriated Tom more than Betty's ability to divine when he's not telling the truth [1]
divine
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] strip; deprive. He was divested of his power to act and could no longer govern. diverstiture N [1]
divest
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] variety; dissimilitude [1]
diversity
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] act of turning aside; pasttime. After studying for several horus, he needed a diversion from work, divert v [1]
diversion
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] differing in some characterists; various [1]
divese
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] differing; deviating. [1]
divergent
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] vary; go in different directions from the same point. [1]
diverge
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] operatic singer; prima donna. Although world famous as a diva, she did not indulge in fits of temperament [1]
diva
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] daily. A farmer cannot neglect his diurnal tasks at any time; cows, for example, must be milked regularly [1]
diurnal
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] upset; distracted by anxiety. The distraught parnts frantically searched the ravine for their lost child [1]
distraught
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] inattentive; distracted, often by anxiety. Jane was so caught up in her wedding plans that her family and friends considered her absent-minded, distrait, aloof and generally usless [1]
distrait
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] twist out of shape. It is difficult to believe the newspaper accounts of the riots because of the way some reporters distort and exaggerate the actual events. [1]
distort
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] honor; contrast; discrimination [1]
distinction
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] purify; refine; concentrate. distill water [1]
distill
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] expand; swell outl. I can tell when he is under stress by the way the veins distend on his forehead [1]
distend
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] reserved or aloof; cold in manner. Her distant greeting made me feel unwelcome from the start (secondary meaning) [1]
distant
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] persuade not to do; discourage. since Tom could not dissuade Huck from running away from home, he decided to run away with his friend. Dissuaion n [1]
dissuade
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] discord; opposite of harmony. [1]
dissonance
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] disintegration; looseness in morals. The profligacy and dissolution of life in Caligula's rome appall some historians. dissolute adj [1]
dissolution
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] squander; waste; scatter. He is a fine artist, but I fear he may dissipate his figts if he keeps wasting his time playing Trivial Pursuit [1]
dissipate
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] pretend; conceal by feigning. Although the governor tried to dissimulate his feelings about the opposing candidate, we all knew he despised his rival [1]
dissimulate
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] dissenting; rebellious. IN the purge that followed the student demonstrations at Tianamen Square, the governemnet hunted down the dissident students and their supporters [1]
dssident
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] formal essay [1]
dissertation
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] disagree. IN the recent Supreme Court decision, Justice O Connor dissented from the majority opinion [1]
dissent
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] distribute; spread; scatter (like sees) B their use of the internet; propangandist have been able to disseminate their pet doctrines to new audiences around the globe [1]
disseminate
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] disguise; pretend. Even tho John tried to dissemble his motive for taking modern dance, we all knew he was there not to dance but to meet girls. [1]
dissemble
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] analysis; cutting apart in order to examine [1]
dissection
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] a formal systematic inquiry; an explanation of the results of a formal inquiry. In his disquisiton, he outlined the steps he had taken in reaching his conclusions [1]
disquisiton
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] uneasiess; anxiety. When Holmes had been gone fr a day, Watson felt only a slight sense of disquietude, but after a week with no word, Watson's uneasiness about his misisng friend had frown into a deep fear for Holmes's safety. disquiet n, v [1]
disquietude
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] argumentative; fond of arguing. Covinced he knwe more than his lawyers, tony was a disputatious client, ready to argue abotu the best way to conduct the case [1]
disputatious
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] amuse. The popularity of Florida as a winter resport is constantly increasing; eachyear, thousands more disport themselves at Miami and Palm Beach [1]
disport
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] lacking in spirit. The coach used all the tricks at his command to buoy up the enthusiasm of his team, which had become dispirited at the loss of the star player. [1]
dispirited
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] scatter. The police fired tear gas into the crowd to disperse the protesters, dispersion n [1]
disperse
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] scatter; drive away; cause to vanish. The bright sunlight eventually dispelled the morning mist [1]
dispel
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] speediness; prompt execution, message sent with all due speed. YOung Napoleon defeated the enmy with all possible dispatch; he then sent a ispatch to headquarters, informing his commander of the great victory [1]
dispatch
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] calm; impartial. KNown in the company for his cool judgment, Bill could impartially examine the causes of a probleml giving a dispassionate analysis of what had gone wrong, and go on to suggest how to correct the mess [1]
dispassionate
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] difference; condition of inequality. Their disparity in rank made no difference at all to the prince and Cinderella [1]
disparity
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] basically different; unrelated [1]
disparate
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] belittle. A doting mother, Emma was more likely to praise her son's crude attempts at art than to disparage them [1]
disparage
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] eliminate from consideration; reject [1]
dismiss
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] cut into small parts. When the AUstrian empire was dismembered, several new countries were established [1]
dismember
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] take apart. When the show closed, they dismantled the scenery before storing it [1]
dismantle
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] remove (forcibl) Thrusting her fist up under the choking mn's lower ribs, Margaret used the Heimlich maneuver to dislodge the food caught in his throat [1]
dislodge
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] act or state of separationo; disunity. Believing the mind could greatly affect the body's health, theholistic doctor rejected the notion of a necessary dis-junction of mind and body [1]
disjunction
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] lacking coherence; separated at the joints [1]
disjointed
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] unprejudiced. Given the judge's political ambitions and the lawyers' financial interest in the case,t he only disinterested person in the courtrooom they have bene the court reporter [1]
disinterested
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] dig up; unearth. They disinterred the body and held an autopsy [1]
disinter
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] lacking genuine candor; insincere. Now that we know that the mayor and his wife are engaged in a bitter divorce fight, we find their earlier remarks regretting their lack of tiem together remarkably disingenuous [1]
disingenuous
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] untidy. Akkikuni's disheveled appearance will hurt his chances working in the real estate industry [1]
disheveled
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] discourage. His failure to pass the bar exam disheartened him [1]
dishearten
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] make discontented. The passengers were disgruntled by the numerous delays [1]
disgruntle
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] surrender something; eject; vomit. Unwilling to disgorge the cash he had stolen from the pension fund, the embezzler tried to run away [1]
disgorge
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] mar the appearance of; spoil. An ugly frown disfigured her normally pleasant face [1]
disfigure
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] uncouple; separate; disconnect. A standard movie routine involves the hero's desperate attempt to disengage a railroad car from a moving train [1]
disengage
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] deprive of a civil right. The imposition of the poll tax effectively disenfranchised poor Southern Blacks, who lost their right to vote [1]
disenfranchise
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] go ashore; unload cargo from a ship. Before the passengers could disembark, they had to pick up their passports from the ship's purser [1]
disembark
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] view with scorn or contempt. In the film funny face, the bookish heroine disdained fahsion models for their lack of intellectual interest [1]
disdain
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] digressing; rambling. As the lecturer wandered from topic to topic, we wondered what if any point there was to his discursive remarks. [1]
discursive
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] able to see difference; prejudiced. A superb interpreter of Picasso, she was sufficiently discriminating to judge the most complex workds of modern art. discrimination N [1]
discriminating
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] prudence in speech, actions; ability to decide responsibly; freedom to act on one's own. Charlotte was the soul of discretion; she enver would repeat anything told to her in confidence [1]
discretion
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] separate; unconnected; consisting of distinct parts. IN programmed instruction, the information to be learned is presented in discrete units, you must repsond correctly to each until before you may advance to the next [1]
discrete
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] lack of consistency; different [1]
discrepancy
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] defame; destroy confidence in; disbelieve. The campaign was highly negative in tone; each candidate tried to discredit the other. [1]
discredit
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] formal discussion; conversation. The youg plato was drawn to the Agora to hear the pphilosophical discourse of Socrates and his followers [1]
discourse
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] disregard. Be prepared to discount what he has to say about his ex wife [1]
discount
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] not harmonious; conflicting. Nothing is quite so discordant as the sound of a junior high school orchestra tuning up [1]
discordant
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] conflict; lack of harmony. Watching Tweediedum battle Tweedledee, Alice wondered what had caused this pointless discord [1]
discord
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] sad. The death of his wife left him disconsolate [1]
disconsolate
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] confuse; upset; embarrass. THe lawyer was disconcerted by the evidence produced by her adversary [1]
disconcert
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] put to rout; defeat; disconcert. This ruse will discomfit the enmy. discomfiture n discomfited [1]
discomfit
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] confused; discomposed. The novice square dancer became so discombobulated that he wandered into the wrong set [1]
discombobulated
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
823c2665_bulary_d_Flashcards___Cram_com__1
[2] revea;. Although comeptitors offered him bribes, he refused to disclose any information about the company's forthcoming product. disclosure n [1]
disclose
[]
gre vocabulary d Flashcards - Cram.com
1
http://www.cram.com/flashcards/gre-vocabulary-d-354519
29/1438042990123.20_20150728002310-00122-ip-10-236-191-2_385940537_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
The efficacy of BENLYSTA has not been evaluated in patients with severe active lupus nephritis or severe active central nervous system lupus. BENLYSTA has not been studied in combination with other biologics or intravenous cyclophosphamide. Use of BENLYSTA is not recommended in these situations [Benlysta indication]
Limitation of use
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
The recommended dosage regimen is 10 mg/kg at 2-week intervals for the first 3 doses and at 4-week intervals thereafter. [Benlysta indication]
Benlysta dose
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Prior to dosing with BENLYSTA, consider administering premedication for prophylaxis against infusion reactions and hypersensitivity reactions [Benlysta indication]
Dosing premeds recommendations
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
1.The diluted solution of BENLYSTA should be administered by intravenous infusion only, over a period of 1 hour [Benlysta indication]
Infusion of Benlysta
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Single‑use vials of belimumab lyophilized powder for injection: •120 mg per vial •400 mg per vial [Benlysta indication]
Dosage form and strength
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
BENLYSTA is contraindicated in patients who have had anaphylaxis with belimumab [Benlysta indication]
Benlysta contraindication
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Mortality (14% B vs 6% placebo) Serious Infections (6% vs 5.2%)(avoid pts with chronic infections) Death due to serious infections (0.3% vs 0.1%) Malignancy Hypersensitivity reactions13% vs 11% Anaphylaxis 0.6% vs 0.4% Infusion reactions 17% vs 15% Depression 16% vs 12% [Benlysta indication]
List warning and precautions
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Live vaccines should not be given for 30 days before or concurrently with BENLYSTA as clinical safety has not been established [Benlysta indication]
Immunization recommendations
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
BENLYSTA has not been studied in combination with other biologic therapies, including B-cell targeted therapies, or intravenous cyclophosphamide. Therefore, use of BENLYSTA is not recommended in combination with biologic therapies or intravenous cyclophosphamide. [Benlysta indication]
Concominant use with other biologics or CTX
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
The data described below reflect exposure to BENLYSTA plus standard of care compared with placebo plus standard of care in 2133 patients in 3 controlled studies. Patients received BENLYSTA at doses of 1 mg/kg (N=673), 4 mg/kg (N=111; Trial 1 only), or 10 mg/kg (N=674) or placebo (N=675) intravenously over a 1-hour peri...
Benlysta clinical trial summary
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
There was no apparent dose-related increase in the majority of adverse events observed with BENLYSTA: Nausea 15% vs 12% Diarrhea 12% vs 9% Pyrexia 10% vs 8% Nasopharyngitis 9% vs 7% Bronchitis 9% vs 5% [Benlysta indication]
Top 5 AEs observed in all 3 clinical trials
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
In Trials 2 and 3, anti-belimumab antibodies were detected in 4 of 563 (0.7%) patients receiving BENLYSTA 10 mg/kg and in 27 of 559 (4.8%) patients receiving BENLYSTA 1 mg/kg [Benlysta indication]
Immunogenicity
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Formal drug interaction studies have not been performed with BENLYSTA. In clinical trials of patients with SLE, BENLYSTA was administered concomitantly with other drugs, including corticosteroids, antimalarials, immunomodulatory and immunosuppressive agents (including azathioprine, methotrexate, and mycophenolate), ang...
Drug interactions
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Pregnancy Category C [Benlysta indication]
Pregnancy category
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
It is not known whether BENLYSTA is excreted in human milk or absorbed systemically after ingestion. However, belimumab was excreted into the milk of cynomolgus monkeys. Because maternal antibodies are excreted in human breast milk, a decision should be made whether to discontinue breastfeeding or to discontinue the dr...
Nursing recommendations
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
In Trial 2 and Trial 3, response rates for the primary endpoint were lower for black subjects in the BENLYSTA group relative to black subjects in the placebo group [see Clinical Studies (14)]. Use with caution in black/African-American patients [Benlysta indication]
Race
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
BENLYSTA (belimumab) is a human IgG1λ monoclonal antibody specific for soluble human B lymphocyte stimulator protein (BLyS, also referred to as BAFF and TNFSF13B [Benlysta indication]
Benlysta description
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
BENLYSTA is a BLyS-specific inhibitor that blocks the binding of soluble BLyS, a B-cell survival factor, to its receptors on B cells. BENLYSTA does not bind B cells directly, but by binding BLyS, BENLYSTA inhibits the survival of B cells, including autoreactive B cells, and reduces the differentiation of B cells into i...
Benlysta MOA
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Terminal half-life (t½, days) 19.4 [Benlysta indication]
Benlysta half life
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Trial 1 enrolled 449 patients and evaluated doses of 1, 4, and 10 mg/kg BENLYSTA plus standard of care compared with placebo plus standard of care over 52 weeks in patients with SLE. Patients had to have a SELENA-SLEDAI score of ≥4 at baseline and a history of autoantibodies (anti-nuclear antibody (ANA) and/or anti-dou...
Trial 1 description
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Trials 2 and 3 were randomized, double-blind, placebo-controlled trials in patients with SLE that were similar in design except duration - Trial 2 was 76 weeks duration and Trial 3 was 52 weeks duration. Eligible patients had active SLE disease, defined as a SELENA-SLEDAI score ≥6, and positive autoantibody test result...
Trial 2 & 3 description
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
Week 52 compared with baseline: •≥4-point reduction in the SELENA-SLEDAI score, and •no new British Isles Lupus Assessment Group (BILAG) A organ domain score or 2 new BILAG B organ domain scores, and •no worsening (<0.30-point increase) in Physician's Global Assessment (PGA) score [Benlysta indication]
Trial 2 & 3 end points
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json
06fa4c12_I_review_Flashcards___Cram_com__Benlysta_indication
In both Trials 2 and 3, the proportion of SLE patients achieving an SRI response, as defined for the primary endpoint, was significantly higher in the BENLYSTA 10 mg/kg group than in the placebo group in both studies. The effect on the SRI was not consistently significantly different for the BENLYSTA 1mg/kg group relat...
Trial 2 & 3 results
[]
Benlysta - PI review Flashcards - Cram.com
Benlysta indication
http://www.cram.com/flashcards/benlysta-pi-review-2160078
29/1438042990123.20_20150728002310-00284-ip-10-236-191-2_373903150_0.json