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8ac20f59-b87d-554f-b095-60841da1b8b3
Define Affinity:
Inhibit or block responses caused by an agonist
Drugs which alter the physiology of a cell by binding to plasma membrane or intracellular receptors
The strength of binding between drug and receptor
Binds to a site other than the agonist-binding domain
4
C
1
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5c9903b3-c33e-5b71-ae59-4c3ed675566b
All benzo's share what similarities?
All are highly alkaline solutions
Composed of a benzene ring fused to a seven-membered diazepine ring
They are safe to be given during pregnancy
Composed of malonic acid and urea
4
B
1
null
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16b6e98c-f287-5400-8015-c6f2daf42d50
Which of the following is not one of the Top 4 side effects of neuraxial opioids?
Sedation
Pruritis
Nausea/Vomitting
Urinary retention
5
A
1
Depressed ventilation
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null
9c517e99-9526-52fb-b1a9-96aab63571b1
Which class of drug would to NOT give to a pt undergoing a cholangiogram?
Benzo's
Barbituates
Opioids
null
3
C
2
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null
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a558ef56-6df9-50df-918d-84f9f448a782
How are barbituate metabolized?
Hepatic Oxidation
Renal oxidation
Glomerular filtration
Broken down in small intestines and excreted in feces
4
A
1
null
null
null
null
null
a97f4627-8e2b-536c-9392-f44cc43f848d
What is an appropriate oral dose for pediatric pre-medication with midazolam?
0.5 mg/kg
1 mg/kg
2-3 mg
10 - 20 mcg/ kg
4
A
1
null
null
null
null
null
2e6c8076-6a98-51e7-8a25-4129103b483a
Which medication would you give to reverse post-op ventilatory depression of Fentanyl while maintaining analgesia?
Nalbuphine
Narcan, carefully titrated
Flumazenil
Switch to Meperidine
4
A
2
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null
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null
6b8566c0-6247-5622-ae82-197ff6b7d19e
The drug most commonly prescribed to treat opioid overdose is?
Flumazenil
Nalbuphine
Naloxone
Butorphanol
4
C
1
null
null
null
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e86542d1-271e-5edc-bd50-e6b2cd553370
What is the elimination half time of Lorazepam?
1-4 hours
21-37 hours
10-20 hours
5-10 hours
4
C
1
null
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null
ae835a26-8c13-5a5c-8565-9b0a5bcfe4a0
You have just given you pt Midazolam, how long would you expect to wait to see onset of the drug?
3-5 minutes
20-25 minutes
30-60 seconds
2 minutes
4
C
1
null
null
null
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null
c260765d-afac-5fe0-ab7e-558118cdec9d
What medication would you give to treat an opioid overdose?
Flumazenil, slow titration of 0.2 mg doses
Nubain 10-20 mg
Lithium
Narcan 1-4 mcg/kg
4
D
1
null
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null
17fff495-3956-5737-b7f4-e3d1421588d6
You are the SRNA for Mr. Chaviano who is just our of surgery. He has a past medical histort of HTN, palpitations, schizophrenia, & GERD. He is shivering in the PACU and the nurse requests something to help. What do you do?
Give some Narcan to reverse your opioids.
Give Meperidine to treat the shivering
Give Fentanyl to treat shivering
Find some warm blankets and cover him up.
4
D
2
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f6592ee6-7444-53f6-8f6f-350c7e96110c
Enkephalin is responsible for stimulating which opioid receptor?
Mu
Kappa
Delta
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3
C
1
null
null
null
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null
175ce3b9-65dd-59f7-89e1-7c17f75cf94f
How much methohexital would you expect to find excreted unchanged in the urine?
< 1%
1-3 %
5-10 %
95%
4
A
1
null
null
null
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null
e412968a-1f1b-5f53-9ba8-0c440fc8ea8f
How long can Methohexital be refrigerated and stable for after mixing?
2 weeks
6 weeks
6 days
1 month
4
B
1
null
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null
76f82048-c36c-5828-b31a-e7c17928cf95
The dose of Benzodiazepines required to reach a desired clinical endpoint is increased in the elderly compared to the younger patient.
True
False
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2
B
1
null
null
null
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null
27456300-2e8b-52a9-9e2c-4403da30af41
What respiratory effects are associated with opioid?
Chest wall flaccidity
Increase RR with decrease Tv
Decrease RR and increase Tv
Increased response to CO2
4
C
1
null
null
null
null
null
2b3e7860-97f3-5a18-886d-a3fe6d8bc6fa
Which of the opioid receptors causes Euphoria, Miosis, Bradycardia, Urinary retention & Hypothermia?
Delta
Mu1
Mu2
Kappa
4
B
1
null
null
null
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null
9c0f3a8d-556c-5459-a3cf-8b9634a364a5
Meperidine acts on which opioid receptors?
Mu & Delta
Only the Mu receptors
Delta & Kappa
Mu & Kappa
4
D
1
null
null
null
null
null
60d1dc88-4f6b-5cac-9abe-f1f160612af5
How much air space should there be in a CO2 absorber?
Equal to Tidal Volume
2-3 times the Tidal Volume
2 L/min
Minimal air space should be allowed.
4
B
1
null
null
null
null
null
c9064c97-b99d-5c48-8a06-91dd03ea502a
What does Henry's law state?
At a constant volume, the pressure of gas is directly proportional to the temperature.
The amount of gas dissolved in a liquid is directly proportional to the partial pressure of the gas over the liquid and indirectly proportional to temperature
At a constant temperature, the volume of gas varies inversely with the pressure.
The total pressure of a mixture of gases in a closed container at a given temperature is equal to the sum of the pressure that each gas exerts
4
B
1
null
null
null
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null
5ccb58b1-6c36-53c3-8e84-092e79936dd0
Where would you find Laminar flow in the body?
Terminal Bronchioles
Carina
Larger Airways
Blood Flowing into the heart
4
A
1
null
null
null
null
null
56bf510b-1a89-53ba-b7ae-a7c8727645a4
Which of these is NOT a distinguishing property of gases?
Strong intermolecular forces
High Velocity
Expand & compress easily
High degree of random Motion
4
A
1
null
null
null
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null
f1fb6cbc-6aa1-59fa-aa75-b84471b3a5da
What is a good example of Grahams Law in Anesthesia practice?
The Venturi Mask effect where increasing velocity of flow decreases pressure exerted on walls of tube.
Being aware of how air flows through larger (turbulent) and smaller (laminar) airways within lungs.
Determining the partial pressure of O2 in a cylinder of air.
Realizing that CO2 diffuses 20x faster than O2 due to increased solubility of CO2.
4
D
1
null
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a905185f-306b-577c-b253-0146ecbcd6d9
The Sagital plane divides the body into...
Left and Right
Superior and Inferior
Anterior and Posterior
Right and Wrong
4
A
1
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null
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d3ba9605-21d7-5f3e-b402-3b24a1edb58f
Which of the following is NOT TRUE about turbulent flow:
It is governed by Reynold’s number (>2000)
Results when molecules of a soltuion encounter walls of a tube in a rough tumbling pattern.
It is caused by high flows, when tube wall is corrugated, & kinks or bends in the system
Occurs when the density of a solution is decreased, and the radius is small
4
D
1
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1e577532-ebbf-5b84-af0b-605ee6feb419
Which of the following will show a FALSE desaturation on your pulse ox monitor?
Carbon Monoxide Poisoning
Hypocarbia
Administration of Methylene Blue dye
Anemia
4
C
1
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null
null
null
204578c1-4139-50fd-a528-de1c8e32507a
What is the hydration of SodaLyme?
14-19%
8-10%
19-23%
33%
4
A
1
null
null
null
null
null
e0795ac7-c24b-54ac-a422-5d50f115c934
Which other gas laws are part of Fick's law?
Charles, Gay-Lusaacs & Boyles Law
Nouba's & Lambert Beer's Law
Henry's & Grahams law
Ohm's & Daltons Law
4
C
1
null
null
null
null
null
7885d8b2-c955-5126-a77a-008daa92cb14
How do OR electrical systems work?
Through a Line isolation monitor which grounds the electrical supply to protect staff and patients from shock.
By providing a ground within each individual piece of equipment as well as in plugs for addition safety.
Through an Isolation transformer which seperates electrical system from OR and provides no ground so you can safely touch one wire.
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3
C
1
null
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null
033af2af-e909-5f0b-ad73-c424ec6e87b0
What is the chemical reaction that occurs within the C02 absorber?
Reduction
Oxidation
Neutralization
Hydrolysis
4
C
1
null
null
null
null
null
1185dae5-42fe-5f6e-91f2-9e4222de7211
Which of the following is not one of the four factors which may change Laminar to Turbulent flow?
High Gas Flows
Changes in Diameter
Volume of Solution
Branching of tubes
4
C
1
null
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null
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null
ff686457-fd20-56ec-971a-4622691fff30
What will happen to your flow if you double the length of your tubing?
You will have 1/16 of flow
You will have 1/2 flow
You will double flow
It will stay the same due to decrease pressure gradient
4
B
2
null
null
null
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null
0ed665bc-be42-5212-a026-42a127a1112a
Which one of the following is a good example of Bernoulli's law?
Being aware of how air flows through larger (turbulent) and smaller (laminar) airways within lungs.
The Venturi Mask effect where increasing velocity of flow decreases pressure exerted on walls of tube.
Determining the partial pressure of O2 in a cylinder of air.
Realizing that CO2 diffuses 20x faster than O2 due to increased solubility of CO2.
4
B
2
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null
null
null
null
671544d2-476d-5d95-8bc8-3d79299186e7
What harmful substance is Desflurane known to cause more than other anesthetic agents upon breakdown in a CO2 aborber?
Trifluoroacetylic acid
Compound A
Your gramma's perfume
Carbon Monoxide
4
D
1
null
null
null
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null
84e36cab-6658-5f92-b8ea-121a3eec0007
What is the MAIN component of SodaLyme?
CaOH
NaOH
KOH
H2O
4
A
1
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null
null
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null
b0a01a75-6b65-5248-8f94-9155195c4b31
Define Suspension.
A solution in which a solute can not be dissolved
The substance which is dissolved in a solution
Homogenous mix of 2 or more substances in equal proportions.
The principal kicking you out of school.
4
A
1
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2f25eeb3-c166-52f4-a132-3c0a23c575e5
Vaporization is NOT dependent upon...
Vapor Pressure of Agent
Temperature of environment
Amount of carrier gas used
Density of Agent
4
D
1
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f622f261-1ccc-507a-9c51-7ce602dac318
Electrocautery (Bovie) is used in surgery to provide homeostasis by burning blood vessels via an electrical current discharged from the machine to the patient. The energy is returned to the patient via a dispersive plate. Which surface is the best choice, from below, to place the dispersive plate?
Thigh or Back
On Big toe
Neck
Wrap around pointer finger
4
A
1
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33c58654-0add-5ed7-a1f6-4d788b419036
Right now you are:
Pretty darn tired of all this studying.
Desperately wanting an alcoholic beverage.
Praying to god you pass these tests.
All of the above.
4
D
1
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null
0f0ac9bf-a72e-57cc-be90-b968199657f8
During your pre-op assessment you find your pt has pulmonary edema. How will this affect Diffusion of your gases?
Increase Distance across membrane, and Increase diffusion
Increase Distance across membrane and decrease diffusion
Decrease distance across membrane and increase diffusion.
Decrease distance across membrane and decrease diffusion.
4
B
2
null
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null
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170d3b76-85e3-5e0e-8574-91149befaa84
What are the end products of the CO2 absorber?
CO, H2O, and Heat
Salts, Carbonates, and H2O
CO, Carbonates, and Heat
Carbonates, H20, Heat
4
D
1
null
null
null
null
null
c1f7e23b-fcc2-50dc-8cbb-49ef13bbad23
Which statement is NOT TRUE regarding the flow of solutions?
The greater the inflow is on one side of the tube than the outflow pressure is on the opposite side of the tube (pressure gradient)the greater the flow
Doubling the radius leads to 16-fold increase in flow
Halving of the radius decreases flow by half
Tripling the radius increases flow 81 fold
4
C
2
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