uuid stringlengths 4 8 | template_uuid stringclasses 40
values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 133 622 | execution_results stringlengths 2 1.14M | query_type stringclasses 2
values | sql_category stringclasses 26
values | bio_category stringclasses 14
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Q17.110 | Q17 | What gene does the drug Loteprednol Etabonate target? | The drug Loteprednol Etabonate targets the gene NR3C1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5556', 'drugName': 'Loteprednol Etabonate', 'tradeNames_string': 'Airex, Alrex, Eysuvis, Inveltys, Lotemax, Lotemax sm', 'drugSynonyms_string': 'CDDD 5604, CDDD-5604, HGP-1, KPI-121, Loteprednol, Loteprednol etabonate, P-5604', 'linkedDiseasesDrug_string': 'Allergic Conjunctivitis (EFO_000... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1296 | Q17 | What gene does the drug Timolol target? | The drug Timolol targets 2 genes: ADRB2 and ADRB1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_761', 'drugName': 'Timolol Maleate', 'tradeNames_string': 'Blocadren, Istalol, Timolol maleate, Timoptic, Timoptic Xe, Timoptic in ocudose, Timoptic-xe', 'drugSynonyms_string': 'Aquanil, NSC-757351, Ophtamolol, Timolol (as maleate), Timolol hydrogen maleate salt, Timolol maleate, Timolol m... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.503 | Q17 | What gene does the drug Loxapine Succinate target? | The drug Loxapine Succinate targets 5 genes: DRD4, HTR2A, DRD2, HTR2C and DRD3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_488', 'drugName': 'Loxapine Succinate', 'tradeNames_string': 'Loxapac, Loxapine, Loxapine succinate, Loxitane', 'drugSynonyms_string': 'CL 71563, CL-71563, Loxapine succinate, NSC-759578', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1975, 'maxClinicalTrialPhase': 4, 'drugIsAppr... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1981 | Q17 | What gene does the drug Colchicine target? | The drug Colchicine targets 15 genes: TUBB, TUBA4A, TUBA3E, TUBB3, TUBB4B, TUBB2A, TUBA1A, TUBA1C, TUBB1, TUBB2B, TUBB8, TUBB6, TUBB4A, TUBA3C and TUBA1B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4743', 'drugName': 'Colchicine', 'tradeNames_string': 'Colchicine, Colcrys, Gloperba, Mitigare', 'drugSynonyms_string': '(-)-colchicine, Colchcine, Colchicine, Colchicinum, Colchineos, Colchisol, NSC-757', 'linkedDiseasesDrug_string': "Coronary Artery Disease (EFO_0001645), Non-St Elevatio... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.869 | Q17 | What gene does the drug Quinidine Sulfate target? | The drug Quinidine Sulfate targets 10 genes: SCN1A, SCN9A, SCN7A, SCN8A, SCN11A, SCN10A, SCN2A, SCN5A, SCN4A and SCN3A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3310', 'drugName': 'Quinidine Sulfate', 'tradeNames_string': 'Cin-quin, Quinicardine, Quinidex, Quinidine sulfate, Quinora', 'drugSynonyms_string': 'AVP-786 COMPONENT QUINIDINE SULFATE, NSC-10004, QUINIDINE SULFATE COMPONENT OF AVP-786, Quinidex extentabs, Quinidine sulfate, Quinidine sulf... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.748 | Q17 | What gene does the drug Teniposide target? | The drug Teniposide targets 2 genes: TOP2A and TOP2B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2612', 'drugName': 'Teniposide', 'tradeNames_string': 'Vumon', 'drugSynonyms_string': 'NSC-122819, Teniposide, VM-26, VM26', 'linkedDiseasesDrug_string': 'Lymphoma (EFO_0000574), Leukemia (EFO_0000565), Acute Lymphoblastic Leukemia (EFO_0000220), Neoplasm (EFO_0000616)', 'yearOfFirstApprov... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1015 | Q17 | What gene does the drug Cisatracurium target? | The drug Cisatracurium targets 5 genes: CHRNB1, CHRNA1, CHRND, CHRNE and CHRNG. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3167', 'drugName': 'Cisatracurium', 'tradeNames_string': 'Nimbex', 'drugSynonyms_string': 'Cisatracurium, Cisatracurium cation, Cisatracurium ion', 'linkedDiseasesDrug_string': 'Acute Respiratory Distress Syndrome (EFO_1000637)', 'yearOfFirstApproval': 1995, 'maxClinicalTrialPhase': 4, 'dr... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1315 | Q17 | What gene does the drug Bromocriptine target? | The drug Bromocriptine targets 3 genes: DRD3, DRD4 and DRD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_630', 'drugName': 'Bromocriptine', 'tradeNames_string': 'Parlodel', 'drugSynonyms_string': '2-bromo-.alpha.-ergocryptine, Bromergocryptine, Bromocriptine, CB-154, Ergocryptine, 2-bromo-, SANDOZ 15-754', 'linkedDiseasesDrug_string': 'Hypogonadism (MONDO_0002146), Adenomyosis (EFO_1001757), ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1297 | Q17 | What gene does the drug Diacetylmorphine target? | The drug Diacetylmorphine targets the gene OPRM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3858', 'drugName': 'Diacetylmorphine', 'tradeNames_string': '', 'drugSynonyms_string': 'Diacetylmorphine, IDS-NH-001, IDS-NH-001(SECT.3), J6.494G', 'linkedDiseasesDrug_string': 'Opioid Use Disorder (EFO_0010702), Drug Dependence (EFO_0003890), Opioid Dependence (EFO_0005611), Heroin Depend... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.609 | Q17 | What gene does the drug Metocurine target? | The drug Metocurine targets 5 genes: CHRNB1, CHRNA1, CHRND, CHRNE and CHRNG. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2699', 'drugName': 'Metocurine Iodide', 'tradeNames_string': 'Metubine iodide', 'drugSynonyms_string': 'Dimethyl tubocurarine iodide, Dimethylchondrocurarine iodide, Dimethyltubocurarinium iodide, Metocurine iodide, NSC-36388', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1982, ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1362 | Q17 | What gene does the drug Alirocumab target? | The drug Alirocumab targets the gene PCSK9. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1637', 'drugName': 'Alirocumab', 'tradeNames_string': 'Praluent', 'drugSynonyms_string': 'Alirocumab, REGN-727, REGN727, SAR-236553, SAR236553', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Coronary Artery Disease (EFO_0001645), Sepsis (HP_0100806), Familial Hypercholeste... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.75 | Q17 | What gene does the drug Echothiophate Iodide target? | The drug Echothiophate Iodide targets the gene ACHE. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2129', 'drugName': 'Echothiophate Iodide', 'tradeNames_string': 'Phospholine iodide', 'drugSynonyms_string': '217-MI, Echodide, Echothiophate iodide, Ecostigmine iodide, Ecothiopate iodide', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1960, 'maxClinicalTrialPhase': 4, 'drugIsAp... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1082 | Q17 | What gene does the drug Frovatriptan target? | The drug Frovatriptan targets 2 genes: HTR1B and HTR1D. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3513', 'drugName': 'Frovatriptan', 'tradeNames_string': 'Migard, Mylatrip', 'drugSynonyms_string': 'Allergo filmtabletten, Frova, Frovatriptan', 'linkedDiseasesDrug_string': 'Migraine Disorder (MONDO_0005277), Pain (EFO_0003843)', 'yearOfFirstApproval': 2001, 'maxClinicalTrialPhase': 4, 'd... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1214 | Q17 | What gene does the drug Bepridil Hydrochloride target? | The drug Bepridil Hydrochloride targets 26 genes: CACNA1C, CACNA1H, CACNG2, CACNG7, CACNA2D1, CACNG6, CACNA1B, CACNG5, CACNG3, CACNG1, CACNB3, CACNB4, CACNA1S, CACNA2D3, CACNA1A, CACNA2D4, CACNA1D, CACNB2, CACNA1G, CACNA1I, CACNG8, CACNB1, CACNG4, CACNA1E, CACNA2D2 and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4565', 'drugName': 'Bepridil Hydrochloride', 'tradeNames_string': 'Bepadin, Vascor', 'drugSynonyms_string': 'Bepridil hydrochloride, Bepridil hydrochloride hydrate, CERM 1978, CERM-1978, Cordium, NSC-758390, Unicordium', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1990, 'maxCli... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1167 | Q17 | What gene does the drug Ibufenac target? | The drug Ibufenac targets 2 genes: PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3586', 'drugName': 'Ibufenac', 'tradeNames_string': 'Dytransin', 'drugSynonyms_string': '(p-isobutylphenyl)acetic acid, Ibufenac, NSC-99976, RD 11654, RD-11654', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.625 | Q17 | What gene does the drug Traxoprodil target? | The drug Traxoprodil is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: GRIN1 and GRIN2B | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3399', 'drugName': 'Traxoprodil', 'tradeNames_string': '', 'drugSynonyms_string': 'CP-101,606, CP-101606, Cp-101,606, Traxoprodil', 'linkedDiseasesDrug_string': 'Stroke (EFO_0000712), Major Depressive Disorder (MONDO_0002009), Parkinson Disease (MONDO_0005180)', 'yearOfFirstApproval': 0, '... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.487 | Q17 | What gene does the drug Testolactone target? | The drug Testolactone targets the gene CYP19A1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2073', 'drugName': 'Testolactone', 'tradeNames_string': 'Fludestrin, Teslac', 'drugSynonyms_string': 'NSC-23759, SQ 9538, SQ-9538, Teolit, Testolactone, Testolactone ciii', 'linkedDiseasesDrug_string': 'Precocious Puberty (MONDO_0000088)', 'yearOfFirstApproval': 1969, 'maxClinicalTrialPhas... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1579 | Q17 | What gene does the drug Amitifadine target? | The drug Amitifadine is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 3 genes: SLC6A4, SLC6A2 and SLC6A3 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1040', 'drugName': 'Amitifadine', 'tradeNames_string': '', 'drugSynonyms_string': 'Amitifadine, DOV 21947, DOV-21,947, DOV-21947, EB1010', 'linkedDiseasesDrug_string': 'Major Depressive Disorder (MONDO_0002009)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.512 | Q17 | What gene does the drug Vorapaxar target? | The drug Vorapaxar targets the gene F2R. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_713', 'drugName': 'Vorapaxar Sulfate', 'tradeNames_string': 'Zontivity', 'drugSynonyms_string': 'SCH 530348, SCH-530348, Vorapaxar sulfate', 'linkedDiseasesDrug_string': 'Stroke (EFO_0000712), Peripheral Arterial Disease (EFO_0004265), Acute Coronary Syndrome (EFO_0005672), Myocardial Infa... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.740 | Q17 | What gene does the drug Lasmiditan target? | The drug Lasmiditan targets the gene HTR1F. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4144', 'drugName': 'Lasmiditan', 'tradeNames_string': '', 'drugSynonyms_string': 'COL-144, LY573144, Lasmiditan', 'linkedDiseasesDrug_string': 'Migraine Disorder (MONDO_0005277), Drug Dependence (EFO_0003890)', 'yearOfFirstApproval': 2020, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.762 | Q17 | What gene does the drug Pegfilgrastim target? | The drug Pegfilgrastim targets the gene CSF3R. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4822', 'drugName': 'Lipegfilgrastim', 'tradeNames_string': 'Lonquex', 'drugSynonyms_string': 'Lipegfilgrastim, XM-22, XM22', 'linkedDiseasesDrug_string': 'Ewing Sarcoma (EFO_0000174), Lymphoma (EFO_0000574), Neoplasm (EFO_0000616)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'dr... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1990 | Q17 | What gene does the drug Clotiazepam target? | The drug Clotiazepam targets 16 genes: GABRG2, GABRE, GABRA4, GABRQ, GABRD, GABRA3, GABRP, GABRA5, GABRG3, GABRB2, GABRB3, GABRG1, GABRA2, GABRB1, GABRA6 and GABRA1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6147', 'drugName': 'Clotiazepam', 'tradeNames_string': 'Clozan', 'drugSynonyms_string': 'Clotiazepam', 'linkedDiseasesDrug_string': 'Anxiety (EFO_0005230)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_string': 'GABRA1 (ENSG00000022355), G... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.784 | Q17 | What gene does the drug Amsacrine target? | The drug Amsacrine targets 2 genes: TOP2A and TOP2B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3938', 'drugName': 'Amsacrine', 'tradeNames_string': 'Amsidyl', 'drugSynonyms_string': 'Acridinylanisidide, Amekrin, Amsacrine, Amsidil, Amsidine, CI-880, Lamasine, M-AMSA, NCI-249992, NSC-156303, NSC-249992, SN-11841, SN-21429', 'linkedDiseasesDrug_string': 'Myelodysplastic Syndrome (EFO_... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1763 | Q17 | What gene does the drug Dupilumab target? | The drug Dupilumab targets the gene IL4R. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2283', 'drugName': 'Dupilumab', 'tradeNames_string': 'Dupixent, Regn668, sar231893', 'drugSynonyms_string': 'Dupilumab, REGN-668, REGN668, SAR-231893, SAR231893', 'linkedDiseasesDrug_string': 'Allergic Bronchopulmonary Aspergillosis (EFO_0007140), Covid-19 (MONDO_0100096), Allergic Rhiniti... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.848 | Q17 | What gene does the drug Sofpironium Bromide target? | The drug Sofpironium Bromide is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 5 genes: CHRM2, CHRM4, CHRM1, CHRM5 and CHRM3 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5796', 'drugName': 'Sofpironium Bromide', 'tradeNames_string': '', 'drugSynonyms_string': 'BBI-4000, Sofpironium bromide', 'linkedDiseasesDrug_string': 'Hyperhidrosis (HP_0000975)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False, 'newLinkedTargets_string': 'C... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.315 | Q17 | What gene does the drug Haloperidol target? | The drug Haloperidol targets 4 genes: DRD3, HTR2A, DRD4 and DRD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_461', 'drugName': 'Haloperidol Decanoate', 'tradeNames_string': 'Haldol, Haldol Dec, Haloperidol decanoate', 'drugSynonyms_string': 'Halomonth, Haloperidol decanoate, R-13,672, R-13672', 'linkedDiseasesDrug_string': 'Psychosis (EFO_0005407), Conduct Disorder (EFO_0004216), Mental Or Behavi... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.816 | Q17 | What gene does the drug Zileuton target? | The drug Zileuton targets the gene ALOX5. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_953', 'drugName': 'Zileuton', 'tradeNames_string': 'Zyflo, Zyflo cr', 'drugSynonyms_string': 'A-64077, ABBOTT-64077, NSC-730712, NSC-759277, Zileuton', 'linkedDiseasesDrug_string': 'Asthma (MONDO_0004979), Lung Cancer (MONDO_0008903), Nicotine Dependence (EFO_0003768), Sickle Cell Anemia (... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.411 | Q17 | What gene does the drug Esketamine target? | The drug Esketamine targets 7 genes: GRIN2B, GRIN2A, GRIN3A, GRIN2D, GRIN3B, GRIN1 and GRIN2C. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4482', 'drugName': 'Esketamine', 'tradeNames_string': '', 'drugSynonyms_string': '(-)-ketamine, Esketamine, Jnj-54135419, Keta-s, Ketamine, (s)-, Ketamine, s-, Ketaved, L-ketamine, S-(-)-ketamine, S-ketamine', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004992), Unipolar Depression (EFO_0... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.826 | Q17 | What gene does the drug Asciminib Hydrochloride target? | The drug Asciminib Hydrochloride targets 2 genes: BCR and ABL1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4114', 'drugName': 'Asciminib Hydrochloride', 'tradeNames_string': 'Scemblix', 'drugSynonyms_string': 'ABL001-AAA, Asciminib hydrochloride, Scemblix', 'linkedDiseasesDrug_string': 'Chronic Myelogenous Leukemia (EFO_0000339)', 'yearOfFirstApproval': 2021, 'maxClinicalTrialPhase': 4, 'drugIs... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1143 | Q17 | What gene does the drug Insulin, Protamine Zinc target? | The drug Insulin, Protamine Zinc targets the gene INSR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3652', 'drugName': 'Insulin, Protamine Zinc', 'tradeNames_string': 'Ins hypurin bov prot zn, Ins prot zn bp', 'drugSynonyms_string': 'Insulin zinc protamine injection (aqueous suspension), Insulin, protamine zinc, Protamine zinc insulin, Protamine zinc insulin injection', 'linkedDiseasesDr... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.313 | Q17 | What gene does the drug Peginterferon Alfa-2B target? | The drug Peginterferon Alfa-2B targets 2 genes: IFNAR1 and IFNAR2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2953', 'drugName': 'Peginterferon Alfa-2B', 'tradeNames_string': 'Peg-Intron, Pegintron', 'drugSynonyms_string': 'Peg-interferon alfa-2b, Pegifn alfa-2b, Peginterferon alfa-2b, Peginterferon-alfa-2b, Pegylated interferon alpha 2b, Sylatron', 'linkedDiseasesDrug_string': 'Cancer (MONDO_0004... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.229 | Q17 | What gene does the drug Oncolysin Cd6 target? | The drug Oncolysin Cd6 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene CD6. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3220', 'drugName': 'Oncolysin Cd6', 'tradeNames_string': '', 'drugSynonyms_string': 'ONCOLYSIN CD6', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'CD6 (ENSG00000013725)', 'numberLinkedTargets': 1}... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1699 | Q17 | What gene does the drug Gonadotropin, Chorionic target? | The drug Gonadotropin, Chorionic targets the gene LHCGR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3636', 'drugName': 'Gonadotropin, Chorionic', 'tradeNames_string': 'A.p.l., Choragon, Chorionic gonadotropin, Equine Chorionic Gonadotropin, Follutein, Gonadotraphon lh, Human Chorionic Gonadotropin, Pregnyl, Profasi, Profast, Progestyl', 'drugSynonyms_string': 'Choriogonadotropin beta, Ch... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1451 | Q17 | What gene does the drug Trenonacog Alfa target? | The drug Trenonacog Alfa is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene F9. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3960', 'drugName': 'Trenonacog Alfa', 'tradeNames_string': 'Ixinity[tm]', 'drugSynonyms_string': 'IB-1001, IB1001, Trenonacog alfa', 'linkedDiseasesDrug_string': 'Hemophilia B (MONDO_0010604), Sandhoff Disease (MONDO_0010006), Tay-Sachs Disease (MONDO_0010100), Niemann-Pick Disease Type C ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1976 | Q17 | What gene does the drug Praliciguat target? | The drug Praliciguat is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 4 genes: GUCY1A1, GUCY1B2, GUCY1A2 and GUCY1B1 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_594', 'drugName': 'Praliciguat', 'tradeNames_string': '', 'drugSynonyms_string': 'IW-1973, Praliciguat', 'linkedDiseasesDrug_string': 'Heart Failure (EFO_0003144)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'GUCY1B1 (ENSG00000... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.814 | Q17 | What gene does the drug Metoprolol target? | The drug Metoprolol targets the gene ADRB1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1081', 'drugName': 'Metoprolol', 'tradeNames_string': '', 'drugSynonyms_string': '(rs)-metoprolol, Beatrolol, CGP-2175, Dl-metoprolol, Lopressidone, Metoprolol, Metoprolol slow release, Seroken, Toprol-XL', 'linkedDiseasesDrug_string': 'Psoriasis (EFO_0000676), Orthostatic Hypotension (EFO... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1847 | Q17 | What gene does the drug Diazepam target? | The drug Diazepam targets 16 genes: GABRG2, GABRE, GABRA4, GABRQ, GABRD, GABRA3, GABRP, GABRA5, GABRG3, GABRB2, GABRB3, GABRG1, GABRA2, GABRB1, GABRA6 and GABRA1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1439', 'drugName': 'Diazepam', 'tradeNames_string': 'Alupram 10, Alupram 2, Alupram 5, Apozepam, Atensine, Dialar, Dialar fte, Diastat, Diastat acudial, Diazepam, Diazepam intensol, Dizac, E-Pam, Paxel, Q-pam, Relanium, Scriptopam, Serenack, Solis, Stesolid, Tensium, Tranimul, Valclair, Va... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.151 | Q17 | What gene does the drug Nebicapone target? | The drug Nebicapone is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene COMT. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1116', 'drugName': 'Nebicapone', 'tradeNames_string': '', 'drugSynonyms_string': 'Nebicapone', 'linkedDiseasesDrug_string': 'Parkinson Disease (MONDO_0005180)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'COMT (ENSG00000093010)... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.781 | Q17 | What gene does the drug Lanatoside C target? | The drug Lanatoside C targets 8 genes: ATP1B1, ATP1A3, ATP1A2, ATP1A4, FXYD2, ATP1A1, ATP1B3 and ATP1B2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2987', 'drugName': 'Lanatoside C', 'tradeNames_string': 'Cedilanid', 'drugSynonyms_string': 'Allocor, Celadigal, Cetosanol, Digilanogen c, Isolanid, Isolanide, Lanatigen c, Lanatoside c, Lanatoside c jp 17, Lanimerck, NSC-119991, NSC-7533', 'linkedDiseasesDrug_string': 'Cardiovascular Dise... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.727 | Q17 | What gene does the drug Teprotumumab target? | The drug Teprotumumab targets the gene IGF1R. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1336', 'drugName': 'Teprotumumab', 'tradeNames_string': 'Tepezza', 'drugSynonyms_string': 'Onilcamotide, R-1507, RG-1507, RG1507, RO-4858696, RO-4858696-000, RO-4858696000, RO4858696, RO4858696-000, RV-001, RV-001 MONOCLONAL, RV001, RV001 MONOCLONAL, Rhoc peptide vaccine rv001v, Tepezza, T... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.820 | Q17 | What gene does the drug Evolocumab target? | The drug Evolocumab targets the gene PCSK9. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_646', 'drugName': 'Evolocumab', 'tradeNames_string': 'Repatha, Repatha sureclick', 'drugSynonyms_string': 'AMG-145, Evolocumab', 'linkedDiseasesDrug_string': 'Hyperlipidemia (MONDO_0021187), Coronary Artery Disease (EFO_0001645), Sepsis (HP_0100806), Lung Cancer (MONDO_0008903), Stroke (EF... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1636 | Q17 | What gene does the drug Liraglutide target? | The drug Liraglutide targets the gene GLP1R. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5245', 'drugName': 'Liraglutide', 'tradeNames_string': 'Saxenda, Victoza', 'drugSynonyms_string': 'Liraglutide, Liraglutide (rdna origin), Liraglutide recombinant, NN-2211, NN-9924, NN2211, NN9924, NNC 90-1170, NNC-90-1170', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Al... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.825 | Q17 | What gene does the drug Sutimlimab target? | The drug Sutimlimab targets the gene C1S. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3495', 'drugName': 'Sutimlimab', 'tradeNames_string': 'Enjaymo', 'drugSynonyms_string': 'BIVV009, Bivv-009, Enjaymo, Sutimlimab, Sutimlimab jome, Sutimlimab-jome, TNT-009, TNT009', 'linkedDiseasesDrug_string': 'Autoimmune Thrombocytopenic Purpura (EFO_0007160), Immune System Disease (EFO_0... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.581 | Q17 | What gene does the drug Bevacizumab target? | The drug Bevacizumab targets the gene VEGFA. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_958', 'drugName': 'Bevacizumab', 'tradeNames_string': 'Avastin', 'drugSynonyms_string': '12-IGG1, AVA-1, Abp-215, Alymsys, BAT-1706, BI 695502, BI695502, BS-503A, Bat 1706, Bat1706, Bevacizumab, Bevacizumab awwb, Bevacizumab beta, Bevacizumab biosimilar (fkb-238), Bevacizumab bvzr, Bevaciz... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.563 | Q17 | What gene does the drug Butabarbital target? | The drug Butabarbital targets 16 genes: GABRG2, GABRE, GABRA4, GABRQ, GABRD, GABRA3, GABRP, GABRA5, GABRG3, GABRB2, GABRB3, GABRG1, GABRA2, GABRB1, GABRA6 and GABRA1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_422', 'drugName': 'Butabarbital', 'tradeNames_string': '', 'drugSynonyms_string': 'Butabarbital, Butabarbital ciii, Butatab, Medarsed, Nilox, Sec-butobarbitone, Secbutabarbital, Secbutobarbitone, Unicelles', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1939, 'maxClinicalTrialPha... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1758 | Q17 | What gene does the drug Mepenzolate target? | The drug Mepenzolate targets 2 genes: CHRM1 and CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3596', 'drugName': 'Mepenzolate', 'tradeNames_string': '', 'drugSynonyms_string': 'Mepenzolate, Mepenzolate bromide free base, Mepenzolate cation, Mepenzolate ion', 'linkedDiseasesDrug_string': 'Gastrointestinal Disease (EFO_0010282)', 'yearOfFirstApproval': 1956, 'maxClinicalTrialPhase': ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1727 | Q17 | What gene does the drug Danazol target? | The drug Danazol targets 2 genes: PGR and AR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4916', 'drugName': 'Danazol', 'tradeNames_string': 'Danazol, Danocrine', 'drugSynonyms_string': 'Danazol, NSC-270916, WIN 17,757, WIN-17757', 'linkedDiseasesDrug_string': 'Fanconi Anemia (MONDO_0019391), Autoimmune Thrombocytopenic Purpura (EFO_0007160), Infertility (EFO_0000545), Mastodyn... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1349 | Q17 | What gene does the drug Rabeprazole target? | The drug Rabeprazole targets 2 genes: ATP4B and ATP4A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5144', 'drugName': 'Rabeprazole Sodium', 'tradeNames_string': 'Aciphex, Aciphex sprinkle, Pariet, Rabeprazole sodium', 'drugSynonyms_string': 'E-3810, E-3810 SODIUM, Idiazole, LY-307640, LY-307640 SODIUM, LY307640 SODIUM, NSC-759270, Rabeprazole na, Rabeprazole sodium, Rabeprazole sodium s... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1161 | Q17 | What gene does the drug Unasnemab target? | The drug Unasnemab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene RGMA. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4076', 'drugName': 'Unasnemab', 'tradeNames_string': '', 'drugSynonyms_string': 'MT-3921, MT3921, Mt-3921, Unasnemab', 'linkedDiseasesDrug_string': 'Spinal Cord Injury (EFO_1001919)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.945 | Q17 | What gene does the drug Carphenazine Maleate target? | The drug Carphenazine Maleate targets 3 genes: HTR2C, HTR2A and DRD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3158', 'drugName': 'Carphenazine Maleate', 'tradeNames_string': 'Proketazine', 'drugSynonyms_string': 'Carfenazine maleate, Carphenazine, Carphenazine dimaleate, Carphenazine maleate, NSC-71755, WY-2445', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase'... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.290 | Q17 | What gene does the drug Hexocyclium target? | The drug Hexocyclium targets 2 genes: CHRM3 and CHRM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3245', 'drugName': 'Hexocyclium', 'tradeNames_string': '', 'drugSynonyms_string': 'Hexocyclium, Hexocyclium cation, Hexocyclium ion', 'linkedDiseasesDrug_string': 'Gastrointestinal Disease (EFO_0010282)', 'yearOfFirstApproval': 1982, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'new... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1947 | Q17 | What gene does the drug Lebrikizumab target? | The drug Lebrikizumab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene IL13. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2381', 'drugName': 'Lebrikizumab', 'tradeNames_string': '', 'drugSynonyms_string': 'Lebrikizumab, MILR-1444A, MILR1444A, PRO-301444, PRO-301444 RG-3637, PRO301444, RG-3637', 'linkedDiseasesDrug_string': 'Idiopathic Pulmonary Fibrosis (EFO_0000768), Asthma (MONDO_0004979), Atopic Eczema (EF... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.973 | Q17 | What gene does the drug Indomethacin target? | The drug Indomethacin targets 2 genes: PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3165', 'drugName': 'Indomethacin', 'tradeNames_string': 'Artracin, Artracin sr, Berlind 75 ret, Flexin-25 continus, Flexin-50 continus, Flexin-75 continus, Imbrilon, Indo-lemmon, Indo-paed, Indocid ret, Indocid-r, Indocin, Indocin sr, Indoderm, Indoflex, Indolar, Indolar sr, Indomax-25, In... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.605 | Q17 | What gene does the drug Capmatinib target? | The drug Capmatinib targets the gene MET. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_910', 'drugName': 'Capmatinib', 'tradeNames_string': '', 'drugSynonyms_string': 'Capmatinib, INC-280, INC280, INCB-28060, INCB-28060 FREE BASE, Incb-28060, NVP-INC280, NVP-INC280-NX, NYP-INC280-NX', 'linkedDiseasesDrug_string': 'Hepatocellular Carcinoma (EFO_0000182), Breast Cancer (MONDO_... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1312 | Q17 | What gene does the drug Fe 202767 target? | The drug Fe 202767 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene OXTR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1641', 'drugName': 'Fe 202767', 'tradeNames_string': '', 'drugSynonyms_string': 'Fe 202767', 'linkedDiseasesDrug_string': 'Premature Birth (EFO_0003917)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'OXTR (ENSG00000180914)', 'nu... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1244 | Q17 | What gene does the drug Cabozantinib S-Malate target? | The drug Cabozantinib S-Malate targets 2 genes: KDR and MET. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3579', 'drugName': 'Cabozantinib S-Malate', 'tradeNames_string': 'Cabometyx, Cometriq', 'drugSynonyms_string': 'BMS-907351, Cabozantinib malate, Cabozantinib s-malate, XL-184, XL184', 'linkedDiseasesDrug_string': 'Ovarian Carcinoma (EFO_0001075), Cancer (MONDO_0004992), Papillary Thyroid C... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1638 | Q17 | What gene does the drug Ticlopidine target? | The drug Ticlopidine targets the gene P2RY12. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3795', 'drugName': 'Ticlopidine', 'tradeNames_string': '', 'drugSynonyms_string': 'Ticlopidin-puren, Ticlopidine', 'linkedDiseasesDrug_string': 'Recurrent Thrombophlebitis (HP_0004419), Internal Carotid Artery Stenosis (EFO_0002615), Stroke (EFO_0000712), Peripheral Arterial Disease (EFO_0... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1588 | Q17 | What gene does the drug Angiotensin Ii target? | The drug Angiotensin Ii targets the gene AGTR1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3311', 'drugName': 'Angiotensin Ii', 'tradeNames_string': '', 'drugSynonyms_string': '5-l-isoleucineangiotensin ii, Angiotensin ii, Angiotensin ii (human type), Angiotensin ii human, Asp-arg-val-tyr-ile-his-pro-phe, Delivert, LJPC-501', 'linkedDiseasesDrug_string': 'Orthostatic Hypotension... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1316 | Q17 | What gene does the drug Amlodipine Benzoate target? | The drug Amlodipine Benzoate targets 4 genes: CACNA1C, CACNA1D, CACNA1S and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5167', 'drugName': 'Amlodipine Benzoate', 'tradeNames_string': 'Katerzia', 'drugSynonyms_string': 'Amlodipine benzoate', 'linkedDiseasesDrug_string': 'Diabetes Mellitus (EFO_0000400), Coronary Artery Disease (EFO_0001645), Stroke (EFO_0000712), Heart Failure (EFO_0003144), Hypertension (EF... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1779 | Q17 | What gene does the drug Cs-1003 target? | The drug Cs-1003 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene PDCD1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6391', 'drugName': 'Cs-1003', 'tradeNames_string': '', 'drugSynonyms_string': 'Antibody cs1003, CS 1003, CS-1003, CS1003, Cs-1003, Cs1003, Nofazinlimab, Recombinant pd-1 mab cs1003', 'linkedDiseasesDrug_string': 'Neoplasm (EFO_0000616), Cancer (MONDO_0004992), Hepatocellular Carcinoma (EFO... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1647 | Q17 | What gene does the drug Mipomersen target? | The drug Mipomersen targets the gene APOB. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3718', 'drugName': 'Mipomersen Sodium', 'tradeNames_string': 'Kynamro', 'drugSynonyms_string': 'ISIS 301012, ISIS-301012, Mipomersen sodium, Mipomersen sodium salt', 'linkedDiseasesDrug_string': 'Familial Hypercholesterolemia (EFO_0004911), Cardiovascular Disease (EFO_0000319), Hypercholes... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1255 | Q17 | What gene does the drug Von Willebrand Factor Human target? | The drug Von Willebrand Factor Human targets the gene VWF. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4930', 'drugName': 'Von Willebrand Factor Human', 'tradeNames_string': '', 'drugSynonyms_string': "Human von willebrand factor, Von willebrand factor, Von willebrand factor (human), Von willebrand factor human, Von willebrand factor, human, Von willebrand's factor", 'linkedDiseasesDrug_str... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1675 | Q17 | What gene does the drug Glpg-1205 target? | The drug Glpg-1205 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene GPR84. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1454', 'drugName': 'Glpg-1205', 'tradeNames_string': '', 'drugSynonyms_string': 'Glpg-1205, Glpg1205', 'linkedDiseasesDrug_string': 'Idiopathic Pulmonary Fibrosis (EFO_0000768), Ulcerative Colitis (EFO_0000729)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1801 | Q17 | What gene does the drug Orp-101 target? | The drug Orp-101 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: OPRK1 and OPRM1 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1458', 'drugName': 'Orp-101', 'tradeNames_string': '', 'drugSynonyms_string': 'Buprenorphine dimer, Orp-101', 'linkedDiseasesDrug_string': 'Irritable Bowel Syndrome (EFO_0000555)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'OP... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.759 | Q17 | What gene does the drug Cisatracurium Besylate target? | The drug Cisatracurium Besylate targets 5 genes: CHRNB1, CHRNA1, CHRND, CHRNE and CHRNG. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3676', 'drugName': 'Cisatracurium Besylate', 'tradeNames_string': 'Cisatracurium besylate, Cisatracurium besylate preservative free, Nimbex, Nimbex preservative free', 'drugSynonyms_string': '51 W89, 51-W-89, 51-W89, 51W-89, 51W89, Cisatracurium (as besilate), Cisatracurium besilate, Cisat... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.616 | Q17 | What gene does the drug Neramexane Mesylate target? | The drug Neramexane Mesylate is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 9 genes: GRIN2B, GRIN2A, GRIN3A, GRIN2D, CHRNA9, GRIN3B, GRIN1, CHRNA10 and GRIN2C | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5793', 'drugName': 'Neramexane Mesylate', 'tradeNames_string': '', 'drugSynonyms_string': 'Neramexane mesilate, Neramexane mesylate', 'linkedDiseasesDrug_string': 'Tinnitus (HP_0000360)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False, 'newLinkedTargets_strin... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1045 | Q17 | What gene does the drug Propantheline Bromide target? | The drug Propantheline Bromide targets 3 genes: CHRM1, CHRM2 and CHRM3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4309', 'drugName': 'Propantheline Bromide', 'tradeNames_string': 'Pro-banthine, Propantheline bromide', 'drugSynonyms_string': 'NSC-757294, Propantheline Bromide, Propantheline bromide', 'linkedDiseasesDrug_string': 'Overactive Bladder (EFO_1000781), Peptic Ulcer Disease (MONDO_0004247)', ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.788 | Q17 | What gene does the drug Sitagliptin Phosphate target? | The drug Sitagliptin Phosphate targets the gene DPP4. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2411', 'drugName': 'Sitagliptin Phosphate', 'tradeNames_string': 'Janumet Xr, Januvia', 'drugSynonyms_string': 'Glactiv, MK-0431, MK0431, ONO-5435, Sitagliptin monophosphate, Sitagliptin monophosphate anhydrous, Sitagliptin monophosphate monohydrate, Sitagliptin phosphate, Sitagliptin phos... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1690 | Q17 | What gene does the drug Naproxen Etemesil target? | The drug Naproxen Etemesil is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: PTGS2 and PTGS1 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5387', 'drugName': 'Naproxen Etemesil', 'tradeNames_string': '', 'drugSynonyms_string': 'LT-NS001, MX-1094, Naproxen etemesil', 'linkedDiseasesDrug_string': 'Osteoarthritis (MONDO_0005178)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_st... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.997 | Q17 | What gene does the drug Ilacirnon target? | The drug Ilacirnon is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene CCR2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1002', 'drugName': 'Ilacirnon', 'tradeNames_string': '', 'drugSynonyms_string': 'CCX-140, CCX140, CCX140-B, Ccx140, Ilacirnon', 'linkedDiseasesDrug_string': 'Type 2 Diabetes Mellitus (MONDO_0005148), Focal Segmental Glomerulosclerosis (EFO_0004236), Diabetic Nephropathy (EFO_0000401)', 'ye... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.499 | Q17 | What gene does the drug Ruplizumab target? | The drug Ruplizumab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene CD40LG. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_230', 'drugName': 'Ruplizumab', 'tradeNames_string': 'Antova', 'drugSynonyms_string': 'BG-9588, BG9588, HU-5C8, Ruplizumab, hu5c8', 'linkedDiseasesDrug_string': 'Lupus Nephritis (EFO_0005761)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'drugIsApproved': False, 'newLinkedTargets... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1320 | Q17 | What gene does the drug Mexiletine Hydrochloride target? | The drug Mexiletine Hydrochloride targets 10 genes: SCN1A, SCN9A, SCN7A, SCN8A, SCN11A, SCN10A, SCN2A, SCN5A, SCN4A and SCN3A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4048', 'drugName': 'Mexiletine Hydrochloride', 'tradeNames_string': 'Mexiletine hydrochloride, Mexitil, Mexitil p.l.', 'drugSynonyms_string': 'KO 1173 CL, KO-1173, KO-1173 CL, KO-1173-CL, Katen, Mexiletine hcl, Mexiletine hydrochloride, NSC-758639', 'linkedDiseasesDrug_string': 'Ventricula... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.281 | Q17 | What gene does the drug Prt-2607 target? | The drug Prt-2607 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene SYK. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1216', 'drugName': 'Prt-2607', 'tradeNames_string': '', 'drugSynonyms_string': 'BIIB-057, P505-15, PRT-062607, Prt-2607', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False, 'newLinkedTargets_string': 'SYK (ENSG00000165025)', 'num... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1848 | Q17 | What gene does the drug Diethylpropion target? | The drug Diethylpropion targets 2 genes: SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1630', 'drugName': 'Diethylpropion', 'tradeNames_string': '', 'drugSynonyms_string': '.alpha.-benzoyltriethylamine, Amfepramone, Anfepramone, Anferpramon, C06954, D07444, Diethylcathinone, Diethylpropion, J4.327C', 'linkedDiseasesDrug_string': 'Obesity (EFO_0001073)', 'yearOfFirstApproval'... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.363 | Q17 | What gene does the drug Ergocalciferol target? | The drug Ergocalciferol targets the gene VDR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_356', 'drugName': 'Ergocalciferol', 'tradeNames_string': 'Calciferol, Calciferol in arach oil, Caltrate, D-forte, Deltalin, Drisdol, Eciferol d2, Ergo-d2, Ergocalciferol, Ergoral d2, Lanes, Oleovitamin D, Osto-d2, Sterogyl, Sterogyl 15h, Sterogyl-15, Uvesterol d, Vitamin D 2, Vitamin d', '... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1179 | Q17 | What gene does the drug Asenapine Maleate target? | The drug Asenapine Maleate targets 2 genes: HTR2A and DRD2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_4103', 'drugName': 'Asenapine Maleate', 'tradeNames_string': 'Saphris', 'drugSynonyms_string': 'Asenapine (as maleate), Asenapine maleate, ORG 5222, ORG-5222', 'linkedDiseasesDrug_string': 'Psychosis (EFO_0005407), Bipolar I Disorder (EFO_0009963), Schizoaffective Disorder (EFO_0005411), B... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.239 | Q17 | What gene does the drug Amivantamab target? | The drug Amivantamab targets 2 genes: MET and EGFR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_61', 'drugName': 'Amivantamab', 'tradeNames_string': 'Rybrevant', 'drugSynonyms_string': 'Amivantamab, Amivantamab vmjw, Amivantamab-vmjw, CNTO-4424, CNTO4424, JNJ 61186372, JNJ-611, JNJ-61186372, JNJ-6372, Jnj 61186372, Jnj-61186372', 'linkedDiseasesDrug_string': 'Salivary Gland Cancer (M... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.557 | Q17 | What gene does the drug Ziralimumab target? | The drug Ziralimumab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene BSG. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3581', 'drugName': 'Ziralimumab', 'tradeNames_string': '', 'drugSynonyms_string': 'ABX-RB2, Ziralimumab', 'linkedDiseasesDrug_string': '', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False, 'newLinkedTargets_string': 'BSG (ENSG00000172270)', 'numberLinkedTargets... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1870 | Q17 | What gene does the drug Pregabalin target? | The drug Pregabalin targets 26 genes: CACNA1C, CACNA1H, CACNG2, CACNG7, CACNA2D1, CACNG6, CACNA1B, CACNG5, CACNG3, CACNG1, CACNB3, CACNB4, CACNA1S, CACNA2D3, CACNA1A, CACNA2D4, CACNA1D, CACNB2, CACNA1G, CACNA1I, CACNG8, CACNB1, CACNG4, CACNA1E, CACNA2D2 and CACNA1F. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2991', 'drugName': 'Pregabalin', 'tradeNames_string': 'Alzain, Axalid, Lecaent, Lyrica, Lyrica cr, Pregabalin, Rewisca', 'drugSynonyms_string': 'CI-1008, NSC-759256, PD-144723, Pregabalin, Pregabalin mylan, Pregabalin sandoz, Pregabalin sandoz gmbh, Pregabalin zentiva, Vronogabic, YNP-1807... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1915 | Q17 | What gene does the drug At-1501 target? | The drug At-1501 is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene CD40LG. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2654', 'drugName': 'At-1501', 'tradeNames_string': '', 'drugSynonyms_string': 'AT-1501, At-1501', 'linkedDiseasesDrug_string': 'Type 1 Diabetes Mellitus (MONDO_0005147), Iga Glomerulonephritis (EFO_0004194), Amyotrophic Lateral Sclerosis (MONDO_0004976)', 'yearOfFirstApproval': 0, 'maxClin... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.211 | Q17 | What gene does the drug Gancotamab target? | The drug Gancotamab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 2 genes: ERBB2 and TOP2A | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2111', 'drugName': 'Gancotamab', 'tradeNames_string': '', 'drugSynonyms_string': 'Gancotamab, MM-302, Mm-302', 'linkedDiseasesDrug_string': 'Breast Cancer (MONDO_0007254)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTargets_string': 'TOP2A (ENS... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1922 | Q17 | What gene does the drug Prenylamine target? | The drug Prenylamine targets 2 genes: SCN5A and CALM1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5448', 'drugName': 'Prenylamine', 'tradeNames_string': '', 'drugSynonyms_string': 'B-436, Prenylamine, Prenylamine lactate', 'linkedDiseasesDrug_string': 'Cardiovascular Disease (EFO_0000319)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 4, 'drugIsApproved': True, 'newLinkedTargets_... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1561 | Q17 | What gene does the drug Osimertinib Mesylate target? | The drug Osimertinib Mesylate targets the gene EGFR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_649', 'drugName': 'Osimertinib Mesylate', 'tradeNames_string': 'Tagrisso', 'drugSynonyms_string': 'AZD-9291 MESYLATE, AZD9291 mesylate, Mereletinib mesilate, Mereletinib mesylate, Osimertinib mesilate, Osimertinib mesylate', 'linkedDiseasesDrug_string': 'Non-Small Cell Lung Carcinoma (EFO_... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.60 | Q17 | What gene does the drug Oxymetazoline Hydrochloride target? | The drug Oxymetazoline Hydrochloride targets 6 genes: ADRA2A, ADRA2C, ADRA1A, ADRA1D, ADRA2B and ADRA1B. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_543', 'drugName': 'Oxymetazoline Hydrochloride', 'tradeNames_string': 'Afrazine, Ocuclear, Rhofade, Upneeq, Visine, Visine l.r.', 'drugSynonyms_string': 'Agn-199201, NSC-757254, Oximetazoline hydrochloride, Oxymetazoline hcl, Oxymetazoline hydrochloride, SCH 9384, SCH-9384', 'linkedDisease... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1835 | Q17 | What gene does the drug Methylphenidate Hydrochloride target? | The drug Methylphenidate Hydrochloride targets 2 genes: SLC6A2 and SLC6A3. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_846', 'drugName': 'Methylphenidate Hydrochloride', 'tradeNames_string': 'Adhansia xr, Aptensio xr, Concerta, Delmosart, Equasym, Equasym xl, Jornay pm, Matoride xl, Medikinet, Medikinet xl, Metadate cd, Metadate er, Methylin, Methylin er, Methylphenidate hydrochloride, Quillichew er, Quill... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1906 | Q17 | What gene does the drug Otlertuzumab target? | The drug Otlertuzumab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene CD37. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1405', 'drugName': 'Otlertuzumab', 'tradeNames_string': '', 'drugSynonyms_string': 'Otlertuzumab, TRU-016', 'linkedDiseasesDrug_string': 'Chronic Lymphocytic Leukemia (EFO_0000095)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 1, 'drugIsApproved': False, 'newLinkedTargets_string': '... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1578 | Q17 | What gene does the drug Tanzisertib target? | The drug Tanzisertib is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 3 genes: MAPK10, MAPK9 and MAPK8 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_1117', 'drugName': 'Tanzisertib', 'tradeNames_string': '', 'drugSynonyms_string': 'CC-930, JNK 930, JNK-930, Tanzisertib', 'linkedDiseasesDrug_string': 'Idiopathic Pulmonary Fibrosis (EFO_0000768)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsApproved': False, 'newLinkedTa... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.368 | Q17 | What gene does the drug Ibritumomab Tiuxetan target? | The drug Ibritumomab Tiuxetan targets the gene MS4A1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3680', 'drugName': 'Ibritumomab Tiuxetan', 'tradeNames_string': 'Zevalin, Zevalin Kit-Indium-111', 'drugSynonyms_string': 'IDEC-129, IDEC-IN2B8, IDEC-Y2B8, IDEC-Y2B8 IDEC-129, Ibritumomab tiuxetan', 'linkedDiseasesDrug_string': 'Multiple Myeloma (EFO_0001378), Follicular Lymphoma (MONDO_00... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.511 | Q17 | What gene does the drug Cilazapril target? | The drug Cilazapril targets the gene ACE. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3862', 'drugName': 'Cilazapril', 'tradeNames_string': 'Inhibace, Vascace', 'drugSynonyms_string': 'Anhydrous cilazapril, Cilazapril, Cilazapril anhydrous, Cilazapril hydrate, Cilazapril monohydrate, Cilazaprilum, Initiss, Justor, RO 31-2848/006, RO-312848006', 'linkedDiseasesDrug_string': ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.815 | Q17 | What gene does the drug Ataciguat target? | The drug Ataciguat is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target 4 genes: GUCY1A1, GUCY1B2, GUCY1A2 and GUCY1B1 | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3371', 'drugName': 'Ataciguat', 'tradeNames_string': '', 'drugSynonyms_string': 'Ataciguat', 'linkedDiseasesDrug_string': 'Aortic Stenosis (EFO_0000266), Pain (EFO_0003843), Intermittent Vascular Claudication (EFO_0003876)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 2, 'drugIsAppr... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1122 | Q17 | What gene does the drug Desflurane target? | The drug Desflurane targets 23 genes: GLRB, GABRG2, GABRA4, KCNK9, GABRB3, GABRA2, KCNK3, KCNK10, GABRA1, GLRA1, GABRE, GABRP, GABRG3, GABRB1, GABRA6, KCNK2, KCNK18, GABRA5, GABRQ, GABRD, GABRA3, GABRB2 and GABRG1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3266', 'drugName': 'Desflurane', 'tradeNames_string': 'Suprane', 'drugSynonyms_string': 'Desflurane, I-653', 'linkedDiseasesDrug_string': 'Post-Operative Sign Or Symptom (EFO_0005323), Kidney Failure (EFO_1002048)', 'yearOfFirstApproval': 1992, 'maxClinicalTrialPhase': 4, 'drugIsApproved':... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1731 | Q17 | What gene does the drug Lumiliximab target? | The drug Lumiliximab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene FCER2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2670', 'drugName': 'Lumiliximab', 'tradeNames_string': '', 'drugSynonyms_string': 'Gomiliximab, IDEC-152, Lumiliximab, P5E8 SI-3401 GOMILIXIMAB, Primatized anti-cd23, ST-152', 'linkedDiseasesDrug_string': 'Leukemia (EFO_0000565), Chronic Lymphocytic Leukemia (EFO_0000095), Lymphoma (EFO_00... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1216 | Q17 | What gene does the drug Gallium Nitrate target? | The drug Gallium Nitrate targets 3 genes: RRM1, RRM2B and RRM2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3632', 'drugName': 'Gallium Nitrate', 'tradeNames_string': 'Ganite', 'drugSynonyms_string': 'Gallium nitrate, Gallium nitrate (anhydrous), Gallium nitrate anhydrous, Gallium nitrate nonahydrate, NSC-15200, Nitric acid, gallium salt', 'linkedDiseasesDrug_string': 'Central Nervous System Neo... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1212 | Q17 | What gene does the drug Vonicog Alfa target? | The drug Vonicog Alfa is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene VWF. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3183', 'drugName': 'Vonicog Alfa', 'tradeNames_string': '', 'drugSynonyms_string': 'BAX 111, BAX-111, Von willebrand factor (recombinant), Vonicog alfa, Vonvendi', 'linkedDiseasesDrug_string': 'Von Willebrand Disease (Orphanet_903)', 'yearOfFirstApproval': 0, 'maxClinicalTrialPhase': 3, 'd... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.971 | Q17 | What gene does the drug Proparacaine Hydrochloride target? | The drug Proparacaine Hydrochloride targets 10 genes: SCN1A, SCN9A, SCN7A, SCN8A, SCN11A, SCN10A, SCN2A, SCN5A, SCN4A and SCN3A. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2948', 'drugName': 'Proparacaine Hydrochloride', 'tradeNames_string': 'Alcaine, Kainair, Ophthaine, Ophthetic, Paracaine, Proparacaine hydrochloride', 'drugSynonyms_string': 'Ak-taine, NSC-759896, Proparacaine hcl, Proparacaine hydrochloride, Proxymetacaine, Proxymetacaine hydrochloride', ... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.805 | Q17 | What gene does the drug Giloralimab target? | The drug Giloralimab is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene CD40. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2944', 'drugName': 'Giloralimab', 'tradeNames_string': '', 'drugSynonyms_string': 'ABBV-927, Abbv-927, Giloralimab, PR-1614645', 'linkedDiseasesDrug_string': 'Pancreatic Carcinoma (EFO_0002618), Cancer (MONDO_0004992), Head And Neck Malignant Neoplasia (EFO_0006859), Breast Cancer (MONDO_0... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.121 | Q17 | What gene does the drug Vilanterol .Alpha.-Phenyl Cinnamate target? | The drug Vilanterol .Alpha.-Phenyl Cinnamate is not approved by the FDA. However, it is currently undergoing clinical trials and indicated to target the gene ADRB2. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_3869', 'drugName': 'Vilanterol .Alpha.-Phenyl Cinnamate', 'tradeNames_string': '', 'drugSynonyms_string': 'GW-642444H, GW642444H, Gw642444h, Vilanterol .alpha.-phenyl cinnamate', 'linkedDiseasesDrug_string': 'Chronic Obstructive Pulmonary Disease (EFO_0000341)', 'yearOfFirstApproval': 0, '... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1322 | Q17 | What gene does the drug Naproxen Sodium target? | The drug Naproxen Sodium targets 2 genes: PTGS2 and PTGS1. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_5291', 'drugName': 'Naproxen Sodium', 'tradeNames_string': 'Aleve, Anaprox, Anaprox ds, Naprelan, Naproxen sodium, Synflex', 'drugSynonyms_string': 'BAY-117031, BAY117031, BAYH6689, Naproxen sodium, Naproxen sodium anhydrous, Naproxen sodium salt, RS-3650', 'linkedDiseasesDrug_string': 'Go... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.1221 | Q17 | What gene does the drug Benserazide target? | The drug Benserazide targets the gene DDC. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_2020', 'drugName': 'Benserazide', 'tradeNames_string': '', 'drugSynonyms_string': 'Benserazide, Benserazide (as hydrochloride), Benserazide hcl, Benserazide hydrochloride, NSC-755907, RO 4-4602, RO-4-4602, Serazide', 'linkedDiseasesDrug_string': 'Parkinson Disease (MONDO_0005180), Restless... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
Q17.528 | Q17 | What gene does the drug Etonogestrel target? | The drug Etonogestrel targets the gene PGR. | SELECT DISTINCT UUID, drugName, tradeNames_string, drugSynonyms_string, linkedDiseasesDrug_string, yearOfFirstApproval, maxClinicalTrialPhase, drugIsApproved, newLinkedTargets_string, numberLinkedTargets
FROM `{project_id}.{dataset_name}.DrugGeneTargets_ComprehensiveAnnotations_updated`
WHERE (LOWER(drugName) LIKE "%... | [{'UUID': 'DrugGeneTargets_v2_6181', 'drugName': 'Etonogestrel', 'tradeNames_string': 'Implanon, Nexplanon', 'drugSynonyms_string': 'Etonogestrel, Implanon, ORG 3236, ORG-3236', 'linkedDiseasesDrug_string': 'Hiv Infection (EFO_0000764), Benign Prostatic Hyperplasia (EFO_0000284), Dysmenorrhea (HP_0100607), Aids (EFO_00... | general | Distinct, Similarity Search, Order By | Genetic Target, Approval Status |
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