uuid stringlengths 4 8 | template_uuid stringclasses 40 values | question stringlengths 13 193 | answer stringlengths 29 2.2k | benchmark_query stringlengths 138 627 | execution_results stringlengths 2 1.14M | query_type stringclasses 2 values | sql_category stringclasses 26 values | bio_category stringclasses 14 values |
|---|---|---|---|---|---|---|---|---|
Q10.1844 | Q10 | Are there any RP11-434I12.2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-434I12.2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-434I12.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.913 | Q10 | Are there any ZPBP2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ZPBP2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ZPBP2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1141 | Q10 | Are there any RP11-723C11.2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-723C11.2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-723C11.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.180 | Q10 | Are there any SLC25A48 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SLC25A48 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SLC25A48' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.729 | Q10 | Are there any CCNT2-AS1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CCNT2-AS1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CCNT2-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1273 | Q10 | Are there any RPS6KL1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RPS6KL1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RPS6KL1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.89 | Q10 | Are there any IDUA SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 6 IDUA SNPs that are significantly associatied with Parkinson's Disease:
• rs6599388 (GWAS p-value: 7.14e-21; b-value: -0.179)
• rs11248061 (GWAS p-value: 4.17e-08; b-value: -0.0998)
• rs11248060 (GWAS p-value: 8.13e-10; b-value: 0.1683)
• rs73211813 (GWAS p-value: 6.97e-10; b-value: -0.1406)
• rs4690326 (GWAS p-value: 2.13e-11; b-value: 0.1172)
• rs11724804 (GWAS p-value: 3.34e-08; b-value: -0.0983) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'IDUA' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_429872', 'Gene': 'IDUA', 'topRSID': 'rs6599388', 'p_GWAS': 7.135477e-21, 'b_GWAS': -0.179}, {'UUID': 'NDD_SMR_genes_all_update_text_1366483', 'Gene': 'IDUA', 'topRSID': 'rs6599388', 'p_GWAS': 7.135477e-21, 'b_GWAS': 0.179}, {'UUID': 'NDD_SMR_genes_all_update_text_429870', 'Gene': 'IDUA', 'topRSID': 'rs6599388', 'p_GWAS': 7.135477e-21, 'b_GWAS': -0.179}, {'UUID': 'NDD_SMR_genes_all_update_text_1430186', 'Gene': 'IDUA', 'topRSID': 'rs4690326', 'p_GWAS': 2.125338e-11, 'b_GWAS': 0.1172}, {'UUID': 'NDD_SMR_genes_all_update_text_1140277', 'Gene': 'IDUA', 'topRSID': 'rs73211813', 'p_GWAS': 6.974456e-10, 'b_GWAS': -0.1406}, {'UUID': 'NDD_SMR_genes_all_update_text_996322', 'Gene': 'IDUA', 'topRSID': 'rs11248060', 'p_GWAS': 8.131674e-10, 'b_GWAS': 0.1683}, {'UUID': 'NDD_SMR_genes_all_update_text_1555642', 'Gene': 'IDUA', 'topRSID': 'rs11724804', 'p_GWAS': 3.342633e-08, 'b_GWAS': -0.0983}, {'UUID': 'NDD_SMR_genes_all_update_text_429875', 'Gene': 'IDUA', 'topRSID': 'rs11248061', 'p_GWAS': 4.169534e-08, 'b_GWAS': -0.0998}, {'UUID': 'NDD_SMR_genes_all_update_text_429876', 'Gene': 'IDUA', 'topRSID': 'rs11248061', 'p_GWAS': 4.169534e-08, 'b_GWAS': -0.0998}, {'UUID': 'NDD_SMR_genes_all_update_text_1323353', 'Gene': 'IDUA', 'topRSID': 'rs11248061', 'p_GWAS': 4.169534e-08, 'b_GWAS': -0.0998}, {'UUID': 'NDD_SMR_genes_all_update_text_429877', 'Gene': 'IDUA', 'topRSID': 'rs11248061', 'p_GWAS': 4.169534e-08, 'b_GWAS': -0.0998}, {'UUID': 'NDD_SMR_genes_all_update_text_1675612', 'Gene': 'IDUA', 'topRSID': 'rs11248061', 'p_GWAS': 4.169534e-08, 'b_GWAS': -0.0998}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1410 | Q10 | Are there any CCNDBP1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CCNDBP1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CCNDBP1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1900 | Q10 | Are there any ZNF205-AS1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ZNF205-AS1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ZNF205-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.463 | Q10 | Are there any RP11-259G18.2 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 11 RP11-259G18.2 SNP that are significantly associatied with Alzheimer's Disease:
• rs199456 (GWAS p-value: 3.03e-09; b-value: -0.0593)
• rs199498 (GWAS p-value: 4.59e-09; b-value: -0.0592)
• rs199528 (GWAS p-value: 1.07e-08; b-value: 0.0572)
• rs199533 (GWAS p-value: 1.29e-08; b-value: -0.0563)
• rs55974014 (GWAS p-value: 1.54e-08; b-value: -0.056)
• rs9468 (GWAS p-value: 2.00e-08; b-value: -0.055)
• rs62061822 (GWAS p-value: 3.29e-08; b-value: -0.0547)
• rs62056812 (GWAS p-value: 3.38e-08; b-value: -0.0541)
• rs17763086 (GWAS p-value: 3.69e-08; b-value: -0.0534)
• rs2532233 (GWAS p-value: 3.69e-08; b-value: -0.0545) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-259G18.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1378570', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs199456', 'p_GWAS': 3.029347e-09, 'b_GWAS': -0.0593}, {'UUID': 'NDD_SMR_genes_all_update_text_1203013', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs199498', 'p_GWAS': 4.590192e-09, 'b_GWAS': -0.0592}, {'UUID': 'NDD_SMR_genes_all_update_text_1610867', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs199528', 'p_GWAS': 1.065241e-08, 'b_GWAS': 0.0572}, {'UUID': 'NDD_SMR_genes_all_update_text_1480160', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1268117', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1454358', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1598270', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1717379', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1157201', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1652500', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1446737', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs9468', 'p_GWAS': 1.997185e-08, 'b_GWAS': -0.055}, {'UUID': 'NDD_SMR_genes_all_update_text_1584312', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs62061822', 'p_GWAS': 3.29012e-08, 'b_GWAS': -0.0547}, {'UUID': 'NDD_SMR_genes_all_update_text_1690047', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs62056812', 'p_GWAS': 3.382131e-08, 'b_GWAS': -0.0541}, {'UUID': 'NDD_SMR_genes_all_update_text_1174599', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs17763086', 'p_GWAS': 3.688444e-08, 'b_GWAS': -0.0534}, {'UUID': 'NDD_SMR_genes_all_update_text_1502450', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs2532233', 'p_GWAS': 3.690625e-08, 'b_GWAS': -0.0545}, {'UUID': 'NDD_SMR_genes_all_update_text_1291762', 'Gene': 'RP11-259G18.2', 'topRSID': 'rs2696673', 'p_GWAS': 4.243841e-08, 'b_GWAS': -0.0559}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1830 | Q10 | Are there any FAM57B SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 8 FAM57B SNPs that are significantly associatied with Alzheimer's Disease:
• rs4788213 (GWAS p-value: 3.30e-10; b-value: 0.0509)
• rs3814877 (GWAS p-value: 2.41e-11; b-value: 0.0561)
• rs12444108 (GWAS p-value: 3.34e-11; b-value: 0.0557)
• rs4238960 (GWAS p-value: 7.72e-11; b-value: 0.054)
• rs7191849 (GWAS p-value: 2.60e-10; b-value: 0.0512)
• rs11642399 (GWAS p-value: 7.93e-10; b-value: -0.0504)
• rs12447915 (GWAS p-value: 5.17e-09; b-value: -0.0479)
• rs4788219 (GWAS p-value: 1.16e-09; b-value: -0.0499) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FAM57B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_109464', 'Gene': 'FAM57B', 'topRSID': 'rs3814877', 'p_GWAS': 2.412826e-11, 'b_GWAS': 0.0561}, {'UUID': 'NDD_SMR_genes_all_update_text_109465', 'Gene': 'FAM57B', 'topRSID': 'rs12444108', 'p_GWAS': 3.335278e-11, 'b_GWAS': 0.0557}, {'UUID': 'NDD_SMR_genes_all_update_text_109466', 'Gene': 'FAM57B', 'topRSID': 'rs4238960', 'p_GWAS': 7.716585e-11, 'b_GWAS': 0.054}, {'UUID': 'NDD_SMR_genes_all_update_text_577433', 'Gene': 'FAM57B', 'topRSID': 'rs7191849', 'p_GWAS': 2.598968e-10, 'b_GWAS': -0.0512}, {'UUID': 'NDD_SMR_genes_all_update_text_109467', 'Gene': 'FAM57B', 'topRSID': 'rs7191849', 'p_GWAS': 2.598968e-10, 'b_GWAS': 0.0512}, {'UUID': 'NDD_SMR_genes_all_update_text_1342780', 'Gene': 'FAM57B', 'topRSID': 'rs7191849', 'p_GWAS': 2.598968e-10, 'b_GWAS': -0.0512}, {'UUID': 'NDD_SMR_genes_all_update_text_109463', 'Gene': 'FAM57B', 'topRSID': 'rs4788213', 'p_GWAS': 3.300756e-10, 'b_GWAS': 0.0509}, {'UUID': 'NDD_SMR_genes_all_update_text_577429', 'Gene': 'FAM57B', 'topRSID': 'rs11642399', 'p_GWAS': 7.92905e-10, 'b_GWAS': -0.0504}, {'UUID': 'NDD_SMR_genes_all_update_text_577431', 'Gene': 'FAM57B', 'topRSID': 'rs4788219', 'p_GWAS': 1.162256e-09, 'b_GWAS': -0.0499}, {'UUID': 'NDD_SMR_genes_all_update_text_577432', 'Gene': 'FAM57B', 'topRSID': 'rs4788219', 'p_GWAS': 1.162256e-09, 'b_GWAS': -0.0499}, {'UUID': 'NDD_SMR_genes_all_update_text_577430', 'Gene': 'FAM57B', 'topRSID': 'rs12447915', 'p_GWAS': 5.174424e-09, 'b_GWAS': -0.0479}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.55 | Q10 | Are there any FCAR SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within FCAR that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'FCAR' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1503 | Q10 | Are there any NSF SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 2 NSF SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs4792831 (GWAS p-value: 1.06e-15; b-value: -0.5293)
• rs2074404 (GWAS p-value: 3.33e-37; b-value: 1.044) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'NSF' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1579432', 'Gene': 'NSF', 'topRSID': 'rs2074404', 'p_GWAS': 3.331984e-37, 'b_GWAS': 1.0438}, {'UUID': 'NDD_SMR_genes_all_update_text_1375938', 'Gene': 'NSF', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}, {'UUID': 'NDD_SMR_genes_all_update_text_1444277', 'Gene': 'NSF', 'topRSID': 'rs4792831', 'p_GWAS': 1.060064e-15, 'b_GWAS': -0.5293}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.650 | Q10 | Are there any VCP SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within VCP that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'VCP' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.684 | Q10 | Are there any CTCF SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CTCF that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CTCF' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.224 | Q10 | Are there any RP11-527H14.4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-527H14.4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-527H14.4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.116 | Q10 | Are there any ZNF549 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within ZNF549 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'ZNF549' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1552 | Q10 | Are there any TMEM179B SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within TMEM179B that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'TMEM179B' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1303 | Q10 | Are there any RP4-543J13.1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP4-543J13.1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP4-543J13.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.987 | Q10 | Are there any GS1-166A23.2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within GS1-166A23.2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'GS1-166A23.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.177 | Q10 | Are there any LINC00710 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within LINC00710 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'LINC00710' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1650 | Q10 | Are there any SLC27A1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SLC27A1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SLC27A1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.596 | Q10 | Are there any CASS4 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 3 CASS4 SNPs that are significantly associatied with Alzheimer's Disease:
• rs6069736 (GWAS p-value: 8.42e-16; b-value: 0.1175)
• rs718022 (GWAS p-value: 1.08e-14; b-value: -0.1144)
• rs6014722 (GWAS p-value: 1.18e-15; b-value: -0.1177) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CASS4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1104439', 'Gene': 'CASS4', 'topRSID': 'rs6069736', 'p_GWAS': 8.419563e-16, 'b_GWAS': 0.1175}, {'UUID': 'NDD_SMR_genes_all_update_text_1653496', 'Gene': 'CASS4', 'topRSID': 'rs6014722', 'p_GWAS': 1.177291e-15, 'b_GWAS': -0.1177}, {'UUID': 'NDD_SMR_genes_all_update_text_1504670', 'Gene': 'CASS4', 'topRSID': 'rs6014722', 'p_GWAS': 1.177291e-15, 'b_GWAS': -0.1177}, {'UUID': 'NDD_SMR_genes_all_update_text_1204217', 'Gene': 'CASS4', 'topRSID': 'rs718022', 'p_GWAS': 1.077752e-14, 'b_GWAS': -0.1144}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1560 | Q10 | Are there any ARHGAP27 SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 4 ARHGAP27 SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs1230103 (GWAS p-value: 1.76e-08; b-value: -0.3217)
• rs11012 (GWAS p-value: 2.11e-42; b-value: 1.608)
• rs169201 (GWAS p-value: 8.55e-46; b-value: 1.588)
• rs1981997 (GWAS p-value: 1.79e-51; b-value: 1.715) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'ARHGAP27' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1283695', 'Gene': 'ARHGAP27', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1732388', 'Gene': 'ARHGAP27', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1041706', 'Gene': 'ARHGAP27', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_560843', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560835', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560839', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1041707', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1041708', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560841', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1041711', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1041712', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1041710', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560834', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1579412', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1444267', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560837', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1041709', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560840', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560836', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560842', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1041713', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_1041705', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560838', 'Gene': 'ARHGAP27', 'topRSID': 'rs11012', 'p_GWAS': 2.1076899999999998e-42, 'b_GWAS': 1.6076}, {'UUID': 'NDD_SMR_genes_all_update_text_560833', 'Gene': 'ARHGAP27', 'topRSID': 'rs1230103', 'p_GWAS': 1.761021e-08, 'b_GWAS': -0.3217}, {'UUID': 'NDD_SMR_genes_all_update_text_1154392', 'Gene': 'ARHGAP27', 'topRSID': 'rs1230103', 'p_GWAS': 1.761021e-08, 'b_GWAS': 0.3217}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.19 | Q10 | Are there any AMIGO2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AMIGO2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'AMIGO2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.429 | Q10 | Are there any ALKBH5 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ALKBH5 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ALKBH5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1345 | Q10 | Are there any DNAJC18 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within DNAJC18 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'DNAJC18' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.289 | Q10 | Are there any LINC00452 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within LINC00452 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LINC00452' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1584 | Q10 | Are there any FAM22D SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within FAM22D that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FAM22D' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.434 | Q10 | Are there any MOK SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within MOK that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'MOK' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1640 | Q10 | Are there any SELK SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SELK that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SELK' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1245 | Q10 | Are there any IL12RB1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within IL12RB1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'IL12RB1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.676 | Q10 | Are there any IL4 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within IL4 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'IL4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.32 | Q10 | Are there any PATJ SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PATJ that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'PATJ' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.934 | Q10 | Are there any RP4-673D20.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP4-673D20.3 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP4-673D20.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.982 | Q10 | Are there any NDUFS2 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 NDUFS2 SNPs that are significantly associatied with Alzheimer's Disease:
• rs4575098 (GWAS p-value: 1.40e-08; b-value: 0.0539)
• rs2070901 (GWAS p-value: 1.01e-08; b-value: -0.0527) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'NDUFS2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_654689', 'Gene': 'NDUFS2', 'topRSID': 'rs2070901', 'p_GWAS': 1.014655e-08, 'b_GWAS': -0.0527}, {'UUID': 'NDD_SMR_genes_all_update_text_40015', 'Gene': 'NDUFS2', 'topRSID': 'rs4575098', 'p_GWAS': 1.397587e-08, 'b_GWAS': 0.0539}, {'UUID': 'NDD_SMR_genes_all_update_text_40012', 'Gene': 'NDUFS2', 'topRSID': 'rs4575098', 'p_GWAS': 1.397587e-08, 'b_GWAS': 0.0539}, {'UUID': 'NDD_SMR_genes_all_update_text_40013', 'Gene': 'NDUFS2', 'topRSID': 'rs4575098', 'p_GWAS': 1.397587e-08, 'b_GWAS': 0.0539}, {'UUID': 'NDD_SMR_genes_all_update_text_40014', 'Gene': 'NDUFS2', 'topRSID': 'rs4575098', 'p_GWAS': 1.397587e-08, 'b_GWAS': 0.0539}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.217 | Q10 | Are there any AC011747.7 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC011747.7 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC011747.7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1130 | Q10 | Are there any DECR1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within DECR1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'DECR1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.330 | Q10 | Are there any RP11-199F11.2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-199F11.2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-199F11.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.566 | Q10 | Are there any SNAP47 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SNAP47 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SNAP47' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1112 | Q10 | Are there any TLE4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TLE4 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TLE4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.707 | Q10 | Are there any LRRC37A2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are at least 6 LRRC37A2 SNPs that are significantly associatied with Progressive supranuclear palsy:
• rs393152 (GWAS p-value: 8.30e-51; b-value: -1.652)
• rs7225002 (GWAS p-value: 1.75e-11; b-value: 0.3874)
• rs8070723 (GWAS p-value: 2.23e-51; b-value: -1.704)
• rs1981997 (GWAS p-value: 1.79e-51; b-value: 1.715)
• rs12373139 (GWAS p-value: 4.65e-51; b-value: 1.688)
• rs169201 (GWAS p-value: 8.55e-46; b-value: 1.588) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'LRRC37A2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1388487', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1464424', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1478193', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1732402', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1444275', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1283710', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1714163', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1170879', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1264989', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1194223', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1452486', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1596829', 'Gene': 'LRRC37A2', 'topRSID': 'rs1981997', 'p_GWAS': 1.792216e-51, 'b_GWAS': 1.7146}, {'UUID': 'NDD_SMR_genes_all_update_text_1489544', 'Gene': 'LRRC37A2', 'topRSID': 'rs8070723', 'p_GWAS': 2.234221e-51, 'b_GWAS': 1.7039}, {'UUID': 'NDD_SMR_genes_all_update_text_30484', 'Gene': 'LRRC37A2', 'topRSID': 'rs8070723', 'p_GWAS': 2.234221e-51, 'b_GWAS': -1.7039}, {'UUID': 'NDD_SMR_genes_all_update_text_1336298', 'Gene': 'LRRC37A2', 'topRSID': 'rs12373139', 'p_GWAS': 4.650637e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1684941', 'Gene': 'LRRC37A2', 'topRSID': 'rs12373139', 'p_GWAS': 4.650637e-51, 'b_GWAS': 1.6879}, {'UUID': 'NDD_SMR_genes_all_update_text_1604719', 'Gene': 'LRRC37A2', 'topRSID': 'rs393152', 'p_GWAS': 8.302968999999999e-51, 'b_GWAS': 1.6521}, {'UUID': 'NDD_SMR_genes_all_update_text_22220', 'Gene': 'LRRC37A2', 'topRSID': 'rs393152', 'p_GWAS': 8.302968999999999e-51, 'b_GWAS': -1.6521}, {'UUID': 'NDD_SMR_genes_all_update_text_1579429', 'Gene': 'LRRC37A2', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_1646050', 'Gene': 'LRRC37A2', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': -1.5881}, {'UUID': 'NDD_SMR_genes_all_update_text_27915', 'Gene': 'LRRC37A2', 'topRSID': 'rs7225002', 'p_GWAS': 1.747569e-11, 'b_GWAS': 0.3874}, {'UUID': 'NDD_SMR_genes_all_update_text_33474', 'Gene': 'LRRC37A2', 'topRSID': 'rs7225002', 'p_GWAS': 1.747569e-11, 'b_GWAS': 0.3874}, {'UUID': 'NDD_SMR_genes_all_update_text_1154400', 'Gene': 'LRRC37A2', 'topRSID': 'rs7225002', 'p_GWAS': 1.747569e-11, 'b_GWAS': -0.3874}, {'UUID': 'NDD_SMR_genes_all_update_text_1375936', 'Gene': 'LRRC37A2', 'topRSID': 'rs7225002', 'p_GWAS': 1.747569e-11, 'b_GWAS': 0.3874}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1979 | Q10 | Are there any AC093724.2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC093724.2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AC093724.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1189 | Q10 | Are there any RP11-61E11.2 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-61E11.2 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-61E11.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.345 | Q10 | Are there any ITPKB SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ITPKB that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ITPKB' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.636 | Q10 | Are there any RABL2A SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RABL2A that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RABL2A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.150 | Q10 | Are there any RP11-96D1.5 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-96D1.5 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-96D1.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1197 | Q10 | Are there any POU3F2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within POU3F2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'POU3F2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.365 | Q10 | Are there any SLC22A31 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SLC22A31 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'SLC22A31' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.86 | Q10 | Are there any RP4-745E8.2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP4-745E8.2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP4-745E8.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.49 | Q10 | Are there any TRGJ1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TRGJ1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TRGJ1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.474 | Q10 | Are there any UHRF2 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within UHRF2 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'UHRF2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.158 | Q10 | Are there any ARFGEF1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ARFGEF1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'ARFGEF1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.764 | Q10 | Are there any CALD1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CALD1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CALD1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1027 | Q10 | Are there any HNRNPL SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within HNRNPL that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'HNRNPL' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1200 | Q10 | Are there any RP11-303E16.3 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-303E16.3 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-303E16.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1404 | Q10 | Are there any MAP3K14 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within MAP3K14 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'MAP3K14' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1202 | Q10 | Are there any AC004862.6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC004862.6 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AC004862.6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1631 | Q10 | Are there any FDFT1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within FDFT1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'FDFT1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.506 | Q10 | Are there any KAT8 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 4 KAT8 SNPs that are significantly associatied with Alzheimer's Disease:
• rs1549299 (GWAS p-value: 3.16e-09; b-value: 0.0539)
• rs1060506 (GWAS p-value: 5.03e-09; b-value: -0.0532)
• rs59735493 (GWAS p-value: 4.71e-09; b-value: -0.0533)
• rs60996860 (GWAS p-value: 4.70e-08; b-value: -0.0508) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'KAT8' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1157039', 'Gene': 'KAT8', 'topRSID': 'rs1549299', 'p_GWAS': 3.159729e-09, 'b_GWAS': 0.0539}, {'UUID': 'NDD_SMR_genes_all_update_text_1267935', 'Gene': 'KAT8', 'topRSID': 'rs59735493', 'p_GWAS': 4.70898e-09, 'b_GWAS': -0.0533}, {'UUID': 'NDD_SMR_genes_all_update_text_1652098', 'Gene': 'KAT8', 'topRSID': 'rs1060506', 'p_GWAS': 5.030688e-09, 'b_GWAS': -0.0532}, {'UUID': 'NDD_SMR_genes_all_update_text_1246860', 'Gene': 'KAT8', 'topRSID': 'rs1060506', 'p_GWAS': 5.030688e-09, 'b_GWAS': -0.0532}, {'UUID': 'NDD_SMR_genes_all_update_text_1501482', 'Gene': 'KAT8', 'topRSID': 'rs1060506', 'p_GWAS': 5.030688e-09, 'b_GWAS': -0.0532}, {'UUID': 'NDD_SMR_genes_all_update_text_1717196', 'Gene': 'KAT8', 'topRSID': 'rs1060506', 'p_GWAS': 5.030688e-09, 'b_GWAS': -0.0532}, {'UUID': 'NDD_SMR_genes_all_update_text_1378459', 'Gene': 'KAT8', 'topRSID': 'rs60996860', 'p_GWAS': 4.698312e-08, 'b_GWAS': -0.0508}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1670 | Q10 | Are there any NME8 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within NME8 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'NME8' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.182 | Q10 | Are there any RP11-434C1.3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-434C1.3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-434C1.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1419 | Q10 | Are there any AC138783.12 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC138783.12 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'AC138783.12' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1014 | Q10 | Are there any RP5-1166F10.1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP5-1166F10.1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP5-1166F10.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1978 | Q10 | Are there any SYS1 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within SYS1 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'SYS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.864 | Q10 | Are there any ABCA7 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 ABCA7 SNPs that are significantly associatied with Alzheimer's Disease:
• rs3764642 (GWAS p-value: 3.34e-14; b-value: 0.0675)
• rs72973584 (GWAS p-value: 3.53e-17; b-value: 0.1163) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ABCA7' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1343474', 'Gene': 'ABCA7', 'topRSID': 'rs72973584', 'p_GWAS': 3.5301900000000005e-17, 'b_GWAS': 0.1163}, {'UUID': 'NDD_SMR_genes_all_update_text_634279', 'Gene': 'ABCA7', 'topRSID': 'rs3764642', 'p_GWAS': 3.343651e-14, 'b_GWAS': 0.0675}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1620 | Q10 | Are there any CELF1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 1 CELF1 SNP that are significantly associatied with Alzheimer's Disease:
• rs11039409 (GWAS p-value: 1.52e-08; b-value: 0.0498) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CELF1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_608496', 'Gene': 'CELF1', 'topRSID': 'rs11039409', 'p_GWAS': 1.521769e-08, 'b_GWAS': 0.0498}, {'UUID': 'NDD_SMR_genes_all_update_text_608497', 'Gene': 'CELF1', 'topRSID': 'rs11039409', 'p_GWAS': 1.521769e-08, 'b_GWAS': 0.0498}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.534 | Q10 | Are there any AHNAK2 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AHNAK2 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'AHNAK2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.350 | Q10 | Are there any RP11-1281K21.1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP11-1281K21.1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'RP11-1281K21.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1389 | Q10 | Are there any CBLC SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CBLC that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CBLC' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1961 | Q10 | Are there any ANP32E SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ANP32E that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'ANP32E' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1301 | Q10 | Are there any AL807752.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AL807752.1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'AL807752.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1973 | Q10 | Are there any TBC1D9 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within TBC1D9 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'TBC1D9' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1980 | Q10 | Are there any CCDC116 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CCDC116 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'CCDC116' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.608 | Q10 | Are there any OR52E4 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within OR52E4 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'OR52E4' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1050 | Q10 | Are there any DNAJC27-AS1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within DNAJC27-AS1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'DNAJC27-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.246 | Q10 | Are there any AC009499.1 SNPs that have a statistically significant association with Parkinson's Disease? | No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC009499.1 that are significantly associated with Parkinson's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC009499.1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1681 | Q10 | Are there any STH SNPs that have a statistically significant association with Progressive supranuclear palsy? | Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there is at least 1 STH SNP that are significantly associatied with Progressive supranuclear palsy:
• rs393152 (GWAS p-value: 8.30e-51; b-value: -1.652) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'STH' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1154396', 'Gene': 'STH', 'topRSID': 'rs393152', 'p_GWAS': 8.302968999999999e-51, 'b_GWAS': -1.6521}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1799 | Q10 | Are there any IL12A-AS1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within IL12A-AS1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'IL12A-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1717 | Q10 | Are there any RP11-24C3.2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-24C3.2 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-24C3.2' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.316 | Q10 | Are there any RP11-126O1.5 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-126O1.5 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'RP11-126O1.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.441 | Q10 | Are there any TPTE2P6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TPTE2P6 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TPTE2P6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1899 | Q10 | Are there any TBC1D17 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TBC1D17 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'TBC1D17' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1637 | Q10 | Are there any HNRNPH3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within HNRNPH3 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'HNRNPH3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.312 | Q10 | Are there any AC005082.12 SNPs that have a statistically significant association with Parkinson's Disease? | Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 7 AC005082.12 SNPs that are significantly associatied with Parkinson's Disease:
• rs858295 (GWAS p-value: 3.56e-09; b-value: 0.1039)
• rs1637221 (GWAS p-value: 5.19e-09; b-value: -0.1028)
• rs1881200 (GWAS p-value: 4.25e-08; b-value: 0.097)
• rs858289 (GWAS p-value: 4.99e-09; b-value: -0.1035)
• rs1637193 (GWAS p-value: 2.17e-08; b-value: -0.0974)
• rs858300 (GWAS p-value: 4.99e-09; b-value: -0.1035)
• rs274058 (GWAS p-value: 6.50e-09; b-value: -0.1033) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PD' AND Gene = 'AC005082.12' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_447892', 'Gene': 'AC005082.12', 'topRSID': 'rs858295', 'p_GWAS': 3.560659e-09, 'b_GWAS': 0.1039}, {'UUID': 'NDD_SMR_genes_all_update_text_1324773', 'Gene': 'AC005082.12', 'topRSID': 'rs858289', 'p_GWAS': 4.991429e-09, 'b_GWAS': -0.1035}, {'UUID': 'NDD_SMR_genes_all_update_text_1557763', 'Gene': 'AC005082.12', 'topRSID': 'rs858300', 'p_GWAS': 4.991429e-09, 'b_GWAS': -0.1035}, {'UUID': 'NDD_SMR_genes_all_update_text_1025679', 'Gene': 'AC005082.12', 'topRSID': 'rs1637221', 'p_GWAS': 5.191673e-09, 'b_GWAS': -0.1028}, {'UUID': 'NDD_SMR_genes_all_update_text_1593745', 'Gene': 'AC005082.12', 'topRSID': 'rs274058', 'p_GWAS': 6.499484e-09, 'b_GWAS': -0.1033}, {'UUID': 'NDD_SMR_genes_all_update_text_1461949', 'Gene': 'AC005082.12', 'topRSID': 'rs1637193', 'p_GWAS': 2.172128e-08, 'b_GWAS': -0.0974}, {'UUID': 'NDD_SMR_genes_all_update_text_1237815', 'Gene': 'AC005082.12', 'topRSID': 'rs1881200', 'p_GWAS': 4.247829e-08, 'b_GWAS': 0.097}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.436 | Q10 | Are there any CCM2L SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CCM2L that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CCM2L' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.667 | Q10 | Are there any GINS1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within GINS1 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'GINS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.376 | Q10 | Are there any MAPT-AS1 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 8 MAPT-AS1 SNPs that are significantly associatied with Alzheimer's Disease:
• rs56280951 (GWAS p-value: 1.67e-08; b-value: -0.0553)
• rs56189701 (GWAS p-value: 2.38e-08; b-value: -0.0547)
• rs62063845 (GWAS p-value: 3.19e-08; b-value: -0.0542)
• rs3785884 (GWAS p-value: 1.27e-08; b-value: -0.0552)
• rs169201 (GWAS p-value: 4.63e-09; b-value: -0.0586)
• rs112310745 (GWAS p-value: 4.91e-08; b-value: -0.054)
• rs10445363 (GWAS p-value: 4.52e-08; b-value: -0.0536)
• rs62055937 (GWAS p-value: 3.01e-08; b-value: -0.0543) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'MAPT-AS1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_591181', 'Gene': 'MAPT-AS1', 'topRSID': 'rs169201', 'p_GWAS': 4.628672e-09, 'b_GWAS': -0.0586}, {'UUID': 'NDD_SMR_genes_all_update_text_115164', 'Gene': 'MAPT-AS1', 'topRSID': 'rs3785884', 'p_GWAS': 1.265036e-08, 'b_GWAS': -0.0552}, {'UUID': 'NDD_SMR_genes_all_update_text_115161', 'Gene': 'MAPT-AS1', 'topRSID': 'rs56280951', 'p_GWAS': 1.672511e-08, 'b_GWAS': -0.0553}, {'UUID': 'NDD_SMR_genes_all_update_text_115162', 'Gene': 'MAPT-AS1', 'topRSID': 'rs56189701', 'p_GWAS': 2.382712e-08, 'b_GWAS': -0.0547}, {'UUID': 'NDD_SMR_genes_all_update_text_1717376', 'Gene': 'MAPT-AS1', 'topRSID': 'rs62055937', 'p_GWAS': 3.010649e-08, 'b_GWAS': -0.0543}, {'UUID': 'NDD_SMR_genes_all_update_text_115163', 'Gene': 'MAPT-AS1', 'topRSID': 'rs62063845', 'p_GWAS': 3.19115e-08, 'b_GWAS': -0.0542}, {'UUID': 'NDD_SMR_genes_all_update_text_591183', 'Gene': 'MAPT-AS1', 'topRSID': 'rs10445363', 'p_GWAS': 4.515928e-08, 'b_GWAS': -0.0536}, {'UUID': 'NDD_SMR_genes_all_update_text_591182', 'Gene': 'MAPT-AS1', 'topRSID': 'rs112310745', 'p_GWAS': 4.909828e-08, 'b_GWAS': -0.054}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.572 | Q10 | Are there any LRRC32 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LRRC32 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'LRRC32' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1226 | Q10 | Are there any CTD-2528A14.5 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CTD-2528A14.5 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'CTD-2528A14.5' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.184 | Q10 | Are there any RP11-259G18.3 SNPs that have a statistically significant association with Alzheimer's Disease? | Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 8 RP11-259G18.3 SNPs that are significantly associatied with Alzheimer's Disease:
• rs199456 (GWAS p-value: 3.03e-09; b-value: -0.0593)
• rs55974014 (GWAS p-value: 1.54e-08; b-value: -0.056)
• rs2732705 (GWAS p-value: 2.86e-08; b-value: -0.0555)
• rs199533 (GWAS p-value: 1.29e-08; b-value: -0.0563)
• rs169201 (GWAS p-value: 4.63e-09; b-value: -0.0586)
• rs9468 (GWAS p-value: 2.00e-08; b-value: -0.055)
• rs199439 (GWAS p-value: 3.64e-09; b-value: -0.059)
• rs2696673 (GWAS p-value: 4.24e-08; b-value: -0.0559) | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-259G18.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [{'UUID': 'NDD_SMR_genes_all_update_text_1157202', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs199456', 'p_GWAS': 3.029347e-09, 'b_GWAS': -0.0593}, {'UUID': 'NDD_SMR_genes_all_update_text_1378571', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs199456', 'p_GWAS': 3.029347e-09, 'b_GWAS': -0.0593}, {'UUID': 'NDD_SMR_genes_all_update_text_1291763', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs199456', 'p_GWAS': 3.029347e-09, 'b_GWAS': -0.0593}, {'UUID': 'NDD_SMR_genes_all_update_text_1502451', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs199439', 'p_GWAS': 3.635016e-09, 'b_GWAS': -0.059}, {'UUID': 'NDD_SMR_genes_all_update_text_1343156', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs169201', 'p_GWAS': 4.628672e-09, 'b_GWAS': -0.0586}, {'UUID': 'NDD_SMR_genes_all_update_text_1247086', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1480161', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1610868', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': 0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1446738', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1454359', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1268118', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1598271', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1717380', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1174600', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1466648', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs9468', 'p_GWAS': 1.997185e-08, 'b_GWAS': -0.055}, {'UUID': 'NDD_SMR_genes_all_update_text_1203014', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs2732705', 'p_GWAS': 2.856696e-08, 'b_GWAS': -0.0555}, {'UUID': 'NDD_SMR_genes_all_update_text_1652501', 'Gene': 'RP11-259G18.3', 'topRSID': 'rs2696673', 'p_GWAS': 4.243841e-08, 'b_GWAS': -0.0559}] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1115 | Q10 | Are there any RP11-290F24.6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-290F24.6 that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'RP11-290F24.6' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.628 | Q10 | Are there any RP11-313P13.3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-313P13.3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'RP11-313P13.3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1910 | Q10 | Are there any FLAD1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within FLAD1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'FLAD1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1192 | Q10 | Are there any CHRM3 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CHRM3 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'CHRM3' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.940 | Q10 | Are there any ZNF141 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ZNF141 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'ZNF141' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1774 | Q10 | Are there any SETD1A SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SETD1A that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'SETD1A' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1842 | Q10 | Are there any SARNP SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis? | No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SARNP that are significantly associated with Amyotrophic Lateral Sclerosis. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'ALS' AND Gene = 'SARNP' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.1331 | Q10 | Are there any DHTKD1 SNPs that have a statistically significant association with Alzheimer's Disease? | No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within DHTKD1 that are significantly associated with Alzheimer's Disease. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'AD' AND Gene = 'DHTKD1' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
Q10.300 | Q10 | Are there any CCDC47 SNPs that have a statistically significant association with Progressive supranuclear palsy? | No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CCDC47 that are significantly associated with Progressive supranuclear palsy. | SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS
FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full`
WHERE Disease = 'PSP' AND Gene = 'CCDC47' AND p_GWAS < 5e-8
ORDER BY p_GWAS
LIMIT 100 | [] | refined | Distinct, Multi-Filter, Order By | GWAS Significance |
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