Datasets:

uuid
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8
template_uuid
stringclasses
40 values
question
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193
answer
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2.2k
benchmark_query
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627
execution_results
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1.14M
query_type
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sql_category
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26 values
bio_category
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14 values
Q10.1615
Q10
Are there any CCND2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CCND2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'CCND2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.687
Q10
Are there any SMIM10L1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SMIM10L1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SMIM10L1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.621
Q10
Are there any PLAAT1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within PLAAT1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'PLAAT1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.923
Q10
Are there any AC130469.2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC130469.2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'AC130469.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1199
Q10
Are there any CHAC2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CHAC2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CHAC2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.839
Q10
Are there any BCKDK SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within BCKDK that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'BCKDK' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1771
Q10
Are there any RCBTB2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RCBTB2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'RCBTB2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.953
Q10
Are there any RP11-670E13.2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-670E13.2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-670E13.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.185
Q10
Are there any ATP5G1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within ATP5G1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'ATP5G1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1072
Q10
Are there any CPSF3 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CPSF3 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CPSF3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.711
Q10
Are there any APOC1 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 APOC1 SNPs that are significantly associatied with Alzheimer's Disease: • rs1064725 (GWAS p-value: 1.77e-28; b-value: -0.2557) • rs892101 (GWAS p-value: 1.42e-20; b-value: 0.0809)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'APOC1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_637428', 'Gene': 'APOC1', 'topRSID': 'rs1064725', 'p_GWAS': 1.768469e-28, 'b_GWAS': -0.2557}, {'UUID': 'NDD_SMR_genes_all_update_text_1397647', 'Gene': 'APOC1', 'topRSID': 'rs892101', 'p_GWAS': 1.419721e-20, 'b_GWAS': 0.0809}]
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Q10.173
Q10
Are there any ARL17A SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there is at least 12 ARL17A SNP that are significantly associatied with Alzheimer's Disease: • rs2696466 (GWAS p-value: 4.51e-10; b-value: -0.053) • rs58879558 (GWAS p-value: 3.07e-09; b-value: -0.0575) • rs62062271 (GWAS p-value: 1.10e-08; b-value: -0.056) • rs3785884 (GWAS p-value: 1.27e-08; b-value: -0.0552) • rs199533 (GWAS p-value: 1.29e-08; b-value: -0.0563) • rs55974014 (GWAS p-value: 1.54e-08; b-value: -0.056) • rs17573607 (GWAS p-value: 2.68e-08; b-value: -0.0545) • rs62056812 (GWAS p-value: 3.38e-08; b-value: -0.0541) • rs757055 (GWAS p-value: 3.58e-08; b-value: -0.054) • rs2532233 (GWAS p-value: 3.69e-08; b-value: 0.0545)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'ARL17A' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1203023', 'Gene': 'ARL17A', 'topRSID': 'rs2696466', 'p_GWAS': 4.509301e-10, 'b_GWAS': -0.053}, {'UUID': 'NDD_SMR_genes_all_update_text_1396753', 'Gene': 'ARL17A', 'topRSID': 'rs58879558', 'p_GWAS': 3.069546e-09, 'b_GWAS': -0.0575}, {'UUID': 'NDD_SMR_genes_all_update_text_1717386', 'Gene': 'ARL17A', 'topRSID': 'rs58879558', 'p_GWAS': 3.069546e-09, 'b_GWAS': -0.0575}, {'UUID': 'NDD_SMR_genes_all_update_text_1247092', 'Gene': 'ARL17A', 'topRSID': 'rs62062271', 'p_GWAS': 1.101658e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_30836', 'Gene': 'ARL17A', 'topRSID': 'rs3785884', 'p_GWAS': 1.265036e-08, 'b_GWAS': -0.0552}, {'UUID': 'NDD_SMR_genes_all_update_text_1174606', 'Gene': 'ARL17A', 'topRSID': 'rs199533', 'p_GWAS': 1.293899e-08, 'b_GWAS': -0.0563}, {'UUID': 'NDD_SMR_genes_all_update_text_1690054', 'Gene': 'ARL17A', 'topRSID': 'rs55974014', 'p_GWAS': 1.544319e-08, 'b_GWAS': -0.056}, {'UUID': 'NDD_SMR_genes_all_update_text_1454365', 'Gene': 'ARL17A', 'topRSID': 'rs17573607', 'p_GWAS': 2.678883e-08, 'b_GWAS': -0.0545}, {'UUID': 'NDD_SMR_genes_all_update_text_1157208', 'Gene': 'ARL17A', 'topRSID': 'rs62056812', 'p_GWAS': 3.382131e-08, 'b_GWAS': -0.0541}, {'UUID': 'NDD_SMR_genes_all_update_text_1584319', 'Gene': 'ARL17A', 'topRSID': 'rs757055', 'p_GWAS': 3.584179e-08, 'b_GWAS': -0.054}, {'UUID': 'NDD_SMR_genes_all_update_text_1106834', 'Gene': 'ARL17A', 'topRSID': 'rs2532233', 'p_GWAS': 3.690625e-08, 'b_GWAS': 0.0545}, {'UUID': 'NDD_SMR_genes_all_update_text_24569', 'Gene': 'ARL17A', 'topRSID': 'rs56127309', 'p_GWAS': 4.023984e-08, 'b_GWAS': -0.0538}, {'UUID': 'NDD_SMR_genes_all_update_text_28417', 'Gene': 'ARL17A', 'topRSID': 'rs56323304', 'p_GWAS': 4.783287e-08, 'b_GWAS': 0.0535}]
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Q10.296
Q10
Are there any UGT1A3 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within UGT1A3 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'UGT1A3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.554
Q10
Are there any GDF1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within GDF1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'GDF1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.763
Q10
Are there any PILRB SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within PILRB that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'PILRB' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.304
Q10
Are there any INCA1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within INCA1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'INCA1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1878
Q10
Are there any TRAF3IP2-AS1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TRAF3IP2-AS1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'TRAF3IP2-AS1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1093
Q10
Are there any HJURP SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within HJURP that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'HJURP' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1747
Q10
Are there any GSTA4 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within GSTA4 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'GSTA4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1652
Q10
Are there any TSPY26P SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TSPY26P that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'TSPY26P' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.914
Q10
Are there any RP11-142C4.6 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-142C4.6 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP11-142C4.6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1932
Q10
Are there any FAM63B SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within FAM63B that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'FAM63B' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.275
Q10
Are there any RFX2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RFX2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'RFX2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1147
Q10
Are there any QPCT SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within QPCT that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'QPCT' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1589
Q10
Are there any MGC57346 SNPs that have a statistically significant association with Progressive supranuclear palsy?
Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there is at least 1 MGC57346 SNP that are significantly associatied with Progressive supranuclear palsy: • rs169201 (GWAS p-value: 8.55e-46; b-value: 1.588)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'MGC57346' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1041718', 'Gene': 'MGC57346', 'topRSID': 'rs169201', 'p_GWAS': 8.550985e-46, 'b_GWAS': 1.5881}]
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Q10.700
Q10
Are there any REST SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within REST that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'REST' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1765
Q10
Are there any RP1-127C7.6 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within RP1-127C7.6 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'RP1-127C7.6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.488
Q10
Are there any PACS1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within PACS1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'PACS1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.428
Q10
Are there any RP11-370I10.6 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-370I10.6 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-370I10.6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.377
Q10
Are there any RP11-134G8.8 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-134G8.8 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-134G8.8' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1008
Q10
Are there any H2AC18 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within H2AC18 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'H2AC18' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1003
Q10
Are there any DUSP2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within DUSP2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'DUSP2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1940
Q10
Are there any GTPBP10 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within GTPBP10 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'GTPBP10' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.714
Q10
Are there any AC067968.3 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within AC067968.3 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'AC067968.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1335
Q10
Are there any GPR141 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within GPR141 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'GPR141' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1156
Q10
Are there any RP11-310P5.1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-310P5.1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RP11-310P5.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.338
Q10
Are there any TMCO1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TMCO1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'TMCO1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1343
Q10
Are there any OGFOD2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within OGFOD2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'OGFOD2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1593
Q10
Are there any CTD-2245E15.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within CTD-2245E15.3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'CTD-2245E15.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1993
Q10
Are there any PLD3 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within PLD3 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'PLD3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.598
Q10
Are there any AC079779.5 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC079779.5 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'AC079779.5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.16
Q10
Are there any GPR133 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within GPR133 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'GPR133' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1855
Q10
Are there any LIMCH1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within LIMCH1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'LIMCH1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1634
Q10
Are there any ZNF3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ZNF3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'ZNF3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1686
Q10
Are there any CPLX4 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CPLX4 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'CPLX4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.600
Q10
Are there any CTD-3088G3.8 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within CTD-3088G3.8 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CTD-3088G3.8' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.924
Q10
Are there any MED24 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within MED24 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'MED24' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.471
Q10
Are there any ELMO2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ELMO2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'ELMO2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.202
Q10
Are there any TEX22 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TEX22 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'TEX22' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1206
Q10
Are there any KLK2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within KLK2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'KLK2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1056
Q10
Are there any AGER SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AGER that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'AGER' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1195
Q10
Are there any RPLP0P2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RPLP0P2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RPLP0P2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1300
Q10
Are there any YTHDC2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within YTHDC2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'YTHDC2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1276
Q10
Are there any OMA1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within OMA1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'OMA1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1814
Q10
Are there any IGHV4-4 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within IGHV4-4 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'IGHV4-4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1402
Q10
Are there any SLC2A13 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within SLC2A13 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'SLC2A13' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1807
Q10
Are there any GOT2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within GOT2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'GOT2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.661
Q10
Are there any RP11-298O21.5 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-298O21.5 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP11-298O21.5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.560
Q10
Are there any SUB1P2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SUB1P2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SUB1P2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.44
Q10
Are there any HSD3B7 SNPs that have a statistically significant association with Parkinson's Disease?
Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are at least 7 HSD3B7 SNPs that are significantly associatied with Parkinson's Disease: • rs8060857 (GWAS p-value: 3.48e-09; b-value: -0.1081) • rs6950 (GWAS p-value: 2.85e-09; b-value: -0.1087) • rs2305880 (GWAS p-value: 3.48e-09; b-value: -0.1081) • rs62055866 (GWAS p-value: 7.35e-10; b-value: -0.1127) • rs11150600 (GWAS p-value: 1.90e-10; b-value: -0.1172) • rs13708 (GWAS p-value: 4.25e-09; b-value: 0.1075) • rs897986 (GWAS p-value: 1.11e-09; b-value: -0.1115)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'HSD3B7' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1140848', 'Gene': 'HSD3B7', 'topRSID': 'rs11150600', 'p_GWAS': 1.895648e-10, 'b_GWAS': -0.1172}, {'UUID': 'NDD_SMR_genes_all_update_text_974665', 'Gene': 'HSD3B7', 'topRSID': 'rs62055866', 'p_GWAS': 7.345112e-10, 'b_GWAS': -0.1127}, {'UUID': 'NDD_SMR_genes_all_update_text_1435342', 'Gene': 'HSD3B7', 'topRSID': 'rs897986', 'p_GWAS': 1.10886e-09, 'b_GWAS': -0.1115}, {'UUID': 'NDD_SMR_genes_all_update_text_485449', 'Gene': 'HSD3B7', 'topRSID': 'rs6950', 'p_GWAS': 2.852122e-09, 'b_GWAS': -0.1087}, {'UUID': 'NDD_SMR_genes_all_update_text_974663', 'Gene': 'HSD3B7', 'topRSID': 'rs2305880', 'p_GWAS': 3.481743e-09, 'b_GWAS': -0.1081}, {'UUID': 'NDD_SMR_genes_all_update_text_485447', 'Gene': 'HSD3B7', 'topRSID': 'rs8060857', 'p_GWAS': 3.481743e-09, 'b_GWAS': -0.1081}, {'UUID': 'NDD_SMR_genes_all_update_text_1241724', 'Gene': 'HSD3B7', 'topRSID': 'rs13708', 'p_GWAS': 4.245904e-09, 'b_GWAS': 0.1075}, {'UUID': 'NDD_SMR_genes_all_update_text_1476292', 'Gene': 'HSD3B7', 'topRSID': 'rs13708', 'p_GWAS': 4.245904e-09, 'b_GWAS': 0.1075}, {'UUID': 'NDD_SMR_genes_all_update_text_1370179', 'Gene': 'HSD3B7', 'topRSID': 'rs13708', 'p_GWAS': 4.245904e-09, 'b_GWAS': 0.1075}]
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GWAS Significance
Q10.278
Q10
Are there any TBC1D3F SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TBC1D3F that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'TBC1D3F' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.1096
Q10
Are there any NLRP4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within NLRP4 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'NLRP4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.104
Q10
Are there any FAM86HP SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within FAM86HP that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'FAM86HP' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.856
Q10
Are there any TLR4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within TLR4 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'TLR4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.985
Q10
Are there any CARD14 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CARD14 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CARD14' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.948
Q10
Are there any CTC-436P18.1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CTC-436P18.1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CTC-436P18.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.110
Q10
Are there any VKORC1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within VKORC1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'VKORC1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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GWAS Significance
Q10.1296
Q10
Are there any CRHR1-IT1 SNPs that have a statistically significant association with Parkinson's Disease?
Yes, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there is at least 18 CRHR1-IT1 SNP that are significantly associatied with Parkinson's Disease: • rs112560196 (GWAS p-value: 3.63e-21; b-value: -0.2559) • rs9468 (GWAS p-value: 5.02e-21; b-value: -0.2371) • rs62061822 (GWAS p-value: 5.27e-21; b-value: -0.2539) • rs62057067 (GWAS p-value: 9.24e-21; b-value: -0.2523) • rs62055932 (GWAS p-value: 1.10e-20; b-value: -0.2518) • rs62056905 (GWAS p-value: 1.45e-20; b-value: -0.251) • rs4564621 (GWAS p-value: 1.73e-20; b-value: -0.2505) • rs77692262 (GWAS p-value: 1.99e-20; b-value: -0.2501) • rs62055888 (GWAS p-value: 2.23e-20; b-value: -0.2507) • rs56040418 (GWAS p-value: 2.51e-20; b-value: -0.2485)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CRHR1-IT1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1488138', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs112560196', 'p_GWAS': 3.6293299999999995e-21, 'b_GWAS': -0.2559}, {'UUID': 'NDD_SMR_genes_all_update_text_1564782', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs112560196', 'p_GWAS': 3.62933e-21, 'b_GWAS': -0.2559}, {'UUID': 'NDD_SMR_genes_all_update_text_1730062', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs9468', 'p_GWAS': 5.021668e-21, 'b_GWAS': -0.2371}, {'UUID': 'NDD_SMR_genes_all_update_text_1451662', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs62061822', 'p_GWAS': 5.267548e-21, 'b_GWAS': -0.2539}, {'UUID': 'NDD_SMR_genes_all_update_text_1640219', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs62057067', 'p_GWAS': 9.237313e-21, 'b_GWAS': -0.2523}, {'UUID': 'NDD_SMR_genes_all_update_text_1710347', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs62055932', 'p_GWAS': 1.100187e-20, 'b_GWAS': -0.2518}, {'UUID': 'NDD_SMR_genes_all_update_text_1281352', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs62056905', 'p_GWAS': 1.454232e-20, 'b_GWAS': -0.251}, {'UUID': 'NDD_SMR_genes_all_update_text_1328930', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs4564621', 'p_GWAS': 1.7305e-20, 'b_GWAS': -0.2505}, {'UUID': 'NDD_SMR_genes_all_update_text_1262223', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs77692262', 'p_GWAS': 1.988364e-20, 'b_GWAS': -0.2501}, {'UUID': 'NDD_SMR_genes_all_update_text_1370542', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs62055888', 'p_GWAS': 2.2256339999999998e-20, 'b_GWAS': -0.2507}, {'UUID': 'NDD_SMR_genes_all_update_text_1386990', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs56040418', 'p_GWAS': 2.5133949999999998e-20, 'b_GWAS': -0.2485}, {'UUID': 'NDD_SMR_genes_all_update_text_1603775', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs17650860', 'p_GWAS': 2.649229e-20, 'b_GWAS': -0.2345}, {'UUID': 'NDD_SMR_genes_all_update_text_1191169', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs17652520', 'p_GWAS': 2.933996e-20, 'b_GWAS': -0.2333}, {'UUID': 'NDD_SMR_genes_all_update_text_1462892', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs4630591', 'p_GWAS': 2.944142e-20, 'b_GWAS': -0.2462}, {'UUID': 'NDD_SMR_genes_all_update_text_1168834', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs34739559', 'p_GWAS': 4.1343649999999996e-20, 'b_GWAS': -0.2489}, {'UUID': 'NDD_SMR_genes_all_update_text_1435915', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs62056913', 'p_GWAS': 6.812257e-20, 'b_GWAS': -0.2447}, {'UUID': 'NDD_SMR_genes_all_update_text_1594922', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs62063281', 'p_GWAS': 2.940479e-18, 'b_GWAS': -0.2222}, {'UUID': 'NDD_SMR_genes_all_update_text_1679564', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs2696532', 'p_GWAS': 4.591761e-18, 'b_GWAS': -0.2417}, {'UUID': 'NDD_SMR_genes_all_update_text_1242269', 'Gene': 'CRHR1-IT1', 'topRSID': 'rs567299266', 'p_GWAS': 1.356307e-11, 'b_GWAS': -0.2164}]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.503
Q10
Are there any NDUFC2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NDUFC2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'NDUFC2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1981
Q10
Are there any TMEM104 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within TMEM104 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'TMEM104' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.869
Q10
Are there any AC097713.4 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within AC097713.4 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'AC097713.4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.748
Q10
Are there any CMTR2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CMTR2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'CMTR2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1015
Q10
Are there any SPTA1 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SPTA1 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SPTA1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1315
Q10
Are there any RP11-613M10.6 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-613M10.6 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-613M10.6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1297
Q10
Are there any KRT8P38 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within KRT8P38 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'KRT8P38' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.609
Q10
Are there any RP11-770G2.2 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RP11-770G2.2 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RP11-770G2.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1362
Q10
Are there any NAMPT SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within NAMPT that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'NAMPT' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.75
Q10
Are there any ACSM1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within ACSM1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'ACSM1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1082
Q10
Are there any SNAP23 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within SNAP23 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'SNAP23' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1214
Q10
Are there any CTC-429C10.2 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within CTC-429C10.2 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'CTC-429C10.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1167
Q10
Are there any STX6 SNPs that have a statistically significant association with Progressive supranuclear palsy?
Yes, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there is at least 1 STX6 SNP that are significantly associatied with Progressive supranuclear palsy: • rs1411478 (GWAS p-value: 1.86e-09; b-value: -0.3191)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'STX6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1595541', 'Gene': 'STX6', 'topRSID': 'rs1411478', 'p_GWAS': 1.861926e-09, 'b_GWAS': 0.3191}, {'UUID': 'NDD_SMR_genes_all_update_text_1387476', 'Gene': 'STX6', 'topRSID': 'rs1411478', 'p_GWAS': 1.861926e-09, 'b_GWAS': 0.3191}, {'UUID': 'NDD_SMR_genes_all_update_text_1151435', 'Gene': 'STX6', 'topRSID': 'rs1411478', 'p_GWAS': 1.861926e-09, 'b_GWAS': -0.3191}, {'UUID': 'NDD_SMR_genes_all_update_text_509733', 'Gene': 'STX6', 'topRSID': 'rs1411478', 'p_GWAS': 1.861926e-09, 'b_GWAS': -0.3191}, {'UUID': 'NDD_SMR_genes_all_update_text_1642053', 'Gene': 'STX6', 'topRSID': 'rs1411478', 'p_GWAS': 1.861926e-09, 'b_GWAS': -0.3191}, {'UUID': 'NDD_SMR_genes_all_update_text_1438377', 'Gene': 'STX6', 'topRSID': 'rs1411478', 'p_GWAS': 1.861926e-09, 'b_GWAS': -0.3191}, {'UUID': 'NDD_SMR_genes_all_update_text_1282152', 'Gene': 'STX6', 'topRSID': 'rs1411478', 'p_GWAS': 1.861926e-09, 'b_GWAS': 0.3191}]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.625
Q10
Are there any AC007796.1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC007796.1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'AC007796.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.487
Q10
Are there any RP11-876N24.5 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within RP11-876N24.5 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'RP11-876N24.5' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1579
Q10
Are there any CTC-529P8.1 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within CTC-529P8.1 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'CTC-529P8.1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.512
Q10
Are there any RP11-400K9.4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-400K9.4 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RP11-400K9.4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.740
Q10
Are there any BBS9 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within BBS9 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'BBS9' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.762
Q10
Are there any SCAF4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within SCAF4 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'SCAF4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1990
Q10
Are there any IGFBP6 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within IGFBP6 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'IGFBP6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
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Distinct, Multi-Filter, Order By
GWAS Significance
Q10.784
Q10
Are there any AC007387.2 SNPs that have a statistically significant association with Parkinson's Disease?
No, according to the largest European genome-wide meta-analysis of Parkinson's Disease (Nalls et al., 2019), there are no SNPs within AC007387.2 that are significantly associated with Parkinson's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PD' AND Gene = 'AC007387.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.1763
Q10
Are there any RP5-1029K10.4 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP5-1029K10.4 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RP5-1029K10.4' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.848
Q10
Are there any ABHD17AP6 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within ABHD17AP6 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'ABHD17AP6' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.315
Q10
Are there any AC007773.2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within AC007773.2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'AC007773.2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.816
Q10
Are there any CLU SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 9 CLU SNPs that are significantly associatied with Alzheimer's Disease: • rs1532278 (GWAS p-value: 1.28e-33; b-value: -0.1003) • rs7982 (GWAS p-value: 5.50e-33; b-value: -0.0993) • rs538181 (GWAS p-value: 1.56e-08; b-value: -0.0458) • rs11136000 (GWAS p-value: 4.75e-33; b-value: -0.0994) • rs4732729 (GWAS p-value: 1.27e-10; b-value: -0.0553) • rs34109053 (GWAS p-value: 3.50e-10; b-value: -0.0571) • rs10091215 (GWAS p-value: 8.84e-12; b-value: -0.0621) • rs2070926 (GWAS p-value: 1.71e-32; b-value: 0.0997) • rs73231005 (GWAS p-value: 3.04e-10; b-value: 0.0573)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'CLU' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_78261', 'Gene': 'CLU', 'topRSID': 'rs1532278', 'p_GWAS': 1.277963e-33, 'b_GWAS': -0.1003}, {'UUID': 'NDD_SMR_genes_all_update_text_78264', 'Gene': 'CLU', 'topRSID': 'rs11136000', 'p_GWAS': 4.752314e-33, 'b_GWAS': -0.0994}, {'UUID': 'NDD_SMR_genes_all_update_text_78262', 'Gene': 'CLU', 'topRSID': 'rs7982', 'p_GWAS': 5.495007e-33, 'b_GWAS': -0.0993}, {'UUID': 'NDD_SMR_genes_all_update_text_1340523', 'Gene': 'CLU', 'topRSID': 'rs2070926', 'p_GWAS': 1.714078e-32, 'b_GWAS': 0.0997}, {'UUID': 'NDD_SMR_genes_all_update_text_78267', 'Gene': 'CLU', 'topRSID': 'rs10091215', 'p_GWAS': 8.843152e-12, 'b_GWAS': -0.0621}, {'UUID': 'NDD_SMR_genes_all_update_text_78265', 'Gene': 'CLU', 'topRSID': 'rs4732729', 'p_GWAS': 1.274089e-10, 'b_GWAS': -0.0553}, {'UUID': 'NDD_SMR_genes_all_update_text_1496308', 'Gene': 'CLU', 'topRSID': 'rs73231005', 'p_GWAS': 3.040424e-10, 'b_GWAS': 0.0573}, {'UUID': 'NDD_SMR_genes_all_update_text_78266', 'Gene': 'CLU', 'topRSID': 'rs34109053', 'p_GWAS': 3.502522e-10, 'b_GWAS': -0.0571}, {'UUID': 'NDD_SMR_genes_all_update_text_78263', 'Gene': 'CLU', 'topRSID': 'rs538181', 'p_GWAS': 1.564636e-08, 'b_GWAS': -0.0458}]
refined
Distinct, Multi-Filter, Order By
GWAS Significance
Q10.411
Q10
Are there any OLFML3 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within OLFML3 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'OLFML3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance
Q10.826
Q10
Are there any KLF16 SNPs that have a statistically significant association with Alzheimer's Disease?
Yes, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are at least 2 KLF16 SNPs that are significantly associatied with Alzheimer's Disease: • rs12977787 (GWAS p-value: 4.91e-08; b-value: -0.048) • rs34541064 (GWAS p-value: 2.85e-08; b-value: -0.0494)
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'KLF16' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
[{'UUID': 'NDD_SMR_genes_all_update_text_1611212', 'Gene': 'KLF16', 'topRSID': 'rs34541064', 'p_GWAS': 2.84753e-08, 'b_GWAS': -0.0494}, {'UUID': 'NDD_SMR_genes_all_update_text_1397200', 'Gene': 'KLF16', 'topRSID': 'rs12977787', 'p_GWAS': 4.909828e-08, 'b_GWAS': -0.048}]
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Q10.1143
Q10
Are there any ZNF408 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within ZNF408 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'ZNF408' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.313
Q10
Are there any RHEBL1 SNPs that have a statistically significant association with Alzheimer's Disease?
No, according to the largest European genome-wide meta-analysis of Alzheimer's Disease (Bellenguez, 2022), there are no SNPs within RHEBL1 that are significantly associated with Alzheimer's Disease.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'AD' AND Gene = 'RHEBL1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.229
Q10
Are there any RP11-203L2.3 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within RP11-203L2.3 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'RP11-203L2.3' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1699
Q10
Are there any GOT2P2 SNPs that have a statistically significant association with Amyotrophic Lateral Sclerosis?
No, according to genome-wide analysis of Amyotrophic Lateral Sclerosis (Nicolas et al., 2018), there are no SNPs within GOT2P2 that are significantly associated with Amyotrophic Lateral Sclerosis.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'ALS' AND Gene = 'GOT2P2' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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Q10.1451
Q10
Are there any MAN1A1 SNPs that have a statistically significant association with Progressive supranuclear palsy?
No, according to genome-wide analysis of Progressive supranuclear palsy (Höglinger et al., 2011), there are no SNPs within MAN1A1 that are significantly associated with Progressive supranuclear palsy.
SELECT DISTINCT UUID, Gene, topRSID, p_GWAS, b_GWAS FROM `card-ai-389220.bio_sql_benchmark.NeurodegenerativeDiseases_SMR_Genes_Full` WHERE Disease = 'PSP' AND Gene = 'MAN1A1' AND p_GWAS < 5e-8 ORDER BY p_GWAS LIMIT 100
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GWAS Significance