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Leddy\tet\tal,\t2009\n).\nAnorexia\n\tand\tbulimia\tare\tassociated\twith\tincreased\trisk\tof\tmiscarriage,\tbirth\tdefects,\thyperemesis,\nIUGR,\tand\tmicronutrient\tdeficiencies,\tas\twell\tas\tpostpartum\tdepression\tand\timpaired\tinfant\nbonding.\tFor\tthose\twith\tbinge\teating,\texcessive\tweight\tgain,\tmacros... | [
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rates\tare\tseen.\tThose\tthat\tpurge\tmay\thave\tcaries\tor\tfractured\tteeth\tsevere\tenough\tthat\tthey\tcannot\nchew\tmeat.\nThe\teffect\n\tof\tpregnancy\ton\tthe\tindividual\twith\tan\teating\tdisorder\tvaries,\tbut\t70%\tmay\tshow\nimprovement,\tespecially\twith\tpurging\tbehaviors\t(\nHarris,\t2010\n).\tHowever,... | [
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Harris,\t2010\n).\tHowever,\tpregnancy\tdoes\tnot\tcure\nthe\teating\tdisorder\tand\tsymptoms\toften\tare\texacerbated\tafter\tdelivery.\tIn\tfact,\tin\tsome\tcases\tthe\nnewborn\tis\tseen\tas\t“too\tfat,”\tto\tthe\tpoint\tof\trestricting\tfood,\tadministering\tsuppositories\tor\tenemas,\nor\tinducing\tvomiting.\n\tA\t... | [
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A\tteam\tapproach\tto\ttreating\tthe\tmom\tis\thelpful\tin\tthose\tcases.\nFor\tthe\twoman\twith\tan\teating\tdisorder,\tpregnancy\tmay\tbe\tparticularly\tfrightening\tbecause\tof\tthe\nloss\tof\tcontrol\tand\tdisturbed\tbody\timage.\tAnorexia\tcan\tbe\tdiagnosed\tduring\tpregnancy.\tSubstance | [
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abuse,\tas\twell\tas\tthe\tuse\tof\tlaxatives\tor\tdiet\tpills,\tmay\tbe\tcoping\tmechanisms.\tInsulin\thas\tbeen\tused\nas\ta\tpurging\tmechanism.\tWomen\tmay\tfear\n\tbeing\tweighed\tand\tmay\tneed\treassurance\tthat\tthe\tnausea\nand\tvomiting\tof\tpregnancy\tis\tnot\tnecessarily\ta\tresurgence\tof\tpurging.\tFatigu... | [
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depression\tmay\tbe\tdue\tto\tstarvation.\tThese\tpregnant\twomen\tshould\tbe\ttreated\twith\tparticular\tcare,\nincluding\tfocusing\ton\thealthy\teating\tfor\toptimal\tfetal\tgrowth\tand\tdevelopment\t(see\t\nChapter\t21\n).\nEdema\tand\tleg\tcramps\nMild\tphysiologic\tedema\tis\n\tusually\tpresent\tin\tthe\tthird\ttr... | [
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pathologic,\tgeneralized\tedema\tassociated\twith\tpreeclampsia.\tNormal\tedema\tin\tthe\tlower\textremities\nis\tcaused\tby\tthe\tpressure\tof\tthe\tenlarging\tuterus\ton\tthe\tvena\tcava,\tobstructing\tthe\treturn\tof\tblood\nflow\tto\tthe\theart.\tWhen\ta\twoman\treclines\ton\ther\tside,\tthe\tmechanical\teffect\tis... | [
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extravascular\tfluid\tis\tmobilized\tand\n\teventually\teliminated\tby\tincreased\turine\toutput.\tNo\tdietary\nintervention\tis\trequired,\tassuming\ther\tprotein\tintake\tis\tadequate.\tIf,\thowever,\ther\turine\tis\tdark\nand/or\tshe\thas\tswelling\tin\ther\thands,\tincreased\tfluid\tintake\tis\trecommended\tand\tex... | [
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consumption\tshould\tbe\treduced.\nIncreased\tfluid\tintake\talso\tis\trecommended\tfor\tleg\tcramps.\tWomen\tshould\tbe\tadvised\tto\tstretch\nwith\ttheir\ttoes\tpointing\n\tback\ttoward\ttheir\tbodies\trather\tthan\taway\tfrom\tthem.\tMassage\tand\theat\napplication\tmay\thelp\ttreat\tthe\tcramp.\tOptimal\tcalcium\ti... | [
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cramps.\tThe\tliterature\tis\tconflicting\tabout\tthe\tbenefit\tof\tmagnesium\tsupplementation\tfor\tprevention\nor\ttreatment\tof\tpregnancy-related\tleg\tcramps\t(\nZhou\tet\tal,\t2015\n).\tCaution\tis\tadvised\tagainst\tlarge\nintakes\tof\tsupplements.\nHeartburn\nGastric\tesophageal\treflux\tis\tcommon\tduring\tthe... | [
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The\tpressure\tof\tthe\tenlarged\tuterus\ton\tthe\tintestines\tand\tstomach,\talong\twith\tthe\trelaxation\tof\tthe\nesophageal\tsphincter\tdue\tto\thormonal\tchanges,\tmay\tresult\tin\tregurgitation\tof\tstomach\tcontents\tinto\nthe\tesophagus.\tRelief\tmeasures\tmay\tinclude\teating\tsmaller\tmeals,\tlimiting\tfluids... | [
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caffeine,\tchocolate,\tmint,\tcarbonated\tbeverages,\ttomatoes,\tcitrus,\tfat,\tand\tspicy\tfoods,\tas\twell\tas\nchewing\tgum,\twalking,\tand\tstaying\tupright\tfor\tat\tleast\t3\thours\tafter\ta\tmeal,\tbut\tinterventions\thave\nnot\tbeen\tevaluated\tfor\teffectiveness\t(\nKaiser\tand\tCampbell,\t2014\n).\tUsing\tmor... | [
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).\tUsing\tmore\tpillows\tat\tnight\talso\nmay\thelp\t(see\t\nChapter\t26\n).\nAlthough\theartburn\tmedicines\tcan\tbe\tused,\tthey\tare\tnot\tbenign\tand\tuse\n\tshould\tbe\tlimited.\tTaking\nexcessive\tcalcium\tcarbonate\tcan\tcause\tlife-threatening\tmilk-alkali\tsyndrome\t(hypercalcemia,\trenal | [
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sufficiency,\tand\tmetabolic\talkalosis).\tHypercalcemia-induced\tpancreatitis\thas\talso\tbeen\tdocumented\n(\nTrezevant\tet\tal,\t2017\n).\tThe\tUL\tof\t2500\tmg\tof\telemental\tcalcium\t(food\tplus\tsupplements)\tshould\tbe\nobserved.\tIf\ta\tcouple\tof\tcalcium\tcarbonate\ttablets\t(two\tregular\tstrength\tTums\n\t... | [
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contain\t400\tmg\ncalcium;\ttwo\tultrastrength\ttablets\tprovide\t800\tmg)\tdo\tnot\tresolve\tthe\theartburn,\tswitching\tto\tthose\ncontaining\tmagnesium\tmay\tbe\tbeneficial.\tHowever,\tprolonged\tuse\tof\thigh-dose\tmagnesium-\ncontaining\tantacids\tis\tassociated\twith\toffspring\tkidney\tstones,\thypotonia,\tand\t... | [
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(\nBustos\tet\tal,\t2017\n).\tAntacids\tcontaining\tbicarbonate\tmay\tcause\tmaternal\tand\tfetal\tmetabolic\nacidosis,\n\tas\twell\tas\tfluid\toverload\tand\tare\tnot\trecommended\tin\tpregnancy.\tProton\tpump\tinhibitors\nmay\treduce\tthe\tbioavailability\tof\tmany\tnutrients,\tincluding\tvitamins\tC,\tB\n12\n,\tcalc... | [
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12\n,\tcalcium,\tmagnesium,\tand\nnonheme\tiron.\tThe\tuse\tof\tantacids\talso\tpotentially\tcan\tincrease\tthe\trisk\tof\tfood\tallergies\tby\timpeding\ngastric\tprotein\tdigestion,\tbut\twhether\tthat\ttranslates\tinto\ta\thigher\trisk\tof\tfood\tallergy\tor\tasthma\tfor\nthe\n\tchild\tis\tunclear.\tSome\therbal\tmed... | [
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heartburn.\tHowever,\tcaution\tis\tadvised\tbecause\tanimal\tresearch\tdemonstrates\tsome\tpreparations\tof\naloe\tcontain\tlatex\twhich\tmight\tinduce\tabortion\tand/or\tstimulate\tmenstruation\t(\nZielinski\tet\tal,\t2015\n).\nHypertension\nHypertension\tobserved\tduring\tpregnancy\tmay\tbe\tpreexisting\tor\tobserved... | [
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time.\tElevated\nblood\tpressure\tthat\tis\tfirst\tdiagnosed\tin\tpregnancy\tmay\tbe\trelatively\tbenign.\tHowever,\ta\trise\tin\nblood\tpressure,\taccompanied\tby\tother\tchanges\tlisted\tin\tthis\tchapter,\tcan\tbe\ta\tsign\tof\t\npreeclampsia\n,\na\tprogressive,\tsystemic\tproblem\taffecting\t3%\tto\t8%\tof\tpregnan... | [
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of\tmaternal\tand\tneonatal\tmorbidity\tand\tmortality\t(\nMyers,\t2017\n).\tAlthough\tdelivery\tresolves\n\tthe\nproblem\tfor\tmost,\tsome\twomen\tdevelop\thypertension\tafter\tdelivery.\nChronic\thypertension\tpredates\tpregnancy\tand\tis\tassociated\twith\tfetal\tgrowth\trestriction.\nAvoidance\tof\tsevere\thyperten... | [
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someone\twith\tpreexisting\thypertension\tis\tunclear\t(see\t\nChapter\t32\n).\tAppropriate\tweight\tgain,\ta\nmodified\tDietary\tApproaches\tto\tStop\tHypertension\n\t(DASH)\tdiet\t(see\t\nAppendix\t17\n),\tand\tregular\naerobic\texercise\tfor\tthose\twithout\tcomplications\tare\trecommended.\tAlthough\texcessive\tsod... | [
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should\tbe\treduced,\tACOG\thas\tpreviously\trecommended\tthat\tintake\tshould\tnot\tbe\tless\tthan\t2300\nmg/day\t(\nACOG,\t2013c\n).\tCalcium\tsupplementation\tfor\tthose\twith\tlow\tcalcium\tintakes\tmay\tbe\thelpful.\nSome\tantihypertensive\tmedications\tcan\tbe\tused\tduring\tpregnancy\tbut\tmay\tneed\n\tto\tbe\tm... | [
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to\tbe\tmodified\nduring\tbreastfeeding.\nGestational\thypertension\n\tis\tdefined\tas\televated\tblood\tpressure\tthat\tappears\tafter\t20\tweeks\tof\ngestation,\tbut\twithout\tproteinuria\tor\tother\tfindings.\tSome\twomen\t(up\tto\t50%)\tgo\ton\tto\tdevelop | [
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preeclampsia,\twhile\tothers\tmay\thave\tno\trisk\texcept\tthe\televated\tblood\tpressure\t(\nACOG,\t2019\n).\tThey\nare\ttreated\tthe\tsame\tas\tthose\twith\tchronic\thypertension\tand\tmonitored\tfor\n\tworsening\tof\tsymptoms.\nGestational\thypertension\tmay\tpredict\tincreased\trisk\tfor\tfuture\thypertension.\tOpt... | [
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nutrition\tis\timportant,\tincluding\tfocus\ton\tfolate,\tsodium,\tcalcium,\tpotassium,\tiron,\tcopper,\tand\tzinc\nintakes\t(\nTande\tet\tal,\t2013\n).\nSome\twomen\twho\tdevelop\thypertension\tduring\tpregnancy\tgo\ton\tto\tdevelop\tpreeclampsia.\tRisk\nfactors\tinclude\twomen\twho\tare\tprimiparous\tand\tobese,\n\tb... | [
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but\tother\trisk\tfactors\tinclude\ta\tpersonal\tor\nfamily\thistory\tof\tpreeclampsia,\tchronic\thypertension,\tdiabetes\t(type\t1,\ttype\t2,\tor\tGDM),\tchronic\nrenal\tdisease,\thistory\tof\tthrombophilia,\tsystemic\tlupus\terythematosus,\tantiphospholipid\tantibody\nsyndrome,\tobstructive\tsleep\tapnea,\tmultifetal... | [
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0.041101887822151184,
0.03710900619626045,
-0.04239244759082794,
0.04002191498875618,
0.08380287140607834,
-0.004524035379290581,
0.03720276057720184,
0.044... |
[\nMyers,\t2017\n]),\tand\tmaternal\tage\tof\tat\tleast\t35\tyears\t(\nACOG,\t2019\n).\tHowever,\tthe\tpresence\tof\tthese\nrisk\tfactors\tdoesn’t\tnecessarily\tguarantee\tthat\tan\tindividual\twill\tdevelop\tpreeclampsia.\tFor\texample,\nwhile\twomen\twho\tare\tobese\tare\ttwice\tas\tlikely\tto\tdevelop\tpreeclampsia\... | [
0.005561986938118935,
0.04315970838069916,
0.06903845071792603,
-0.05294023081660271,
-0.043556634336709976,
-0.018069742247462273,
0.07442812621593475,
-0.03844079002737999,
-0.023739423602819443,
0.07352820038795471,
0.0803399533033371,
-0.04526761174201965,
0.06316281855106354,
0.004104... |
a\tlower\tBMI,\tonly\tone\tin\tten\twomen\twith\tobesity\tdevelop\tpreeclampsia\t(\nMyers,\t2017\n).\tIn\taddition,\nmost\tcases\tof\tpreeclampsia\toccur\tin\thealthy,\tnulliparous\twomen\twith\tno\n\tapparent\trisk\tfactors\n(\nACOG,\t2019\n).\tPaternal\tfactors\talso\tlikely\tplay\ta\trole.\tRisk\tincreases\twith\tad... | [
-0.004982713144272566,
-0.03709286078810692,
0.05880267545580864,
-0.06871837377548218,
-0.12722332775592804,
0.031748395413160324,
0.04677426069974899,
0.016024325042963028,
-0.03475172072649002,
0.08899787068367004,
0.14229509234428406,
-0.04763791337609291,
0.017809133976697922,
-0.0013... |
paternal\tobesity,\tand\tfamily\thistory\tof\tearly-onset\tCVD.\tPaternal\tgenes\talso\tmay\tbe\timportant—\nincreased\trisk\tfor\tpreeclampsia\tis\tseen\tif\tthe\tman\thas\tfathered\ta\tpreeclamptic\tpregnancy\tor\tif\the\nwas\tborn\tof\ta\tpreeclamptic\tpregnancy\t(\nDekker\tet\tal,\t2011\n).\tMaternal\tsmoking\tredu... | [
-0.03466983512043953,
-0.0323273204267025,
0.013666809536516666,
-0.008206622675061226,
-0.06874795258045197,
0.01914467290043831,
0.012969481758773327,
0.013426963239908218,
-0.05792982876300812,
0.09080646932125092,
0.14251123368740082,
-0.02835126966238022,
-0.03481626883149147,
-0.0273... |
).\tMaternal\tsmoking\treduces\n\tthe\trisk\tby\n35%\t(\nACOG,\t2013c\n),\tbut\tif\tpreeclampsia\toccurs,\tthe\tseverity\tincreases\t(Trogstad\tet\tal,\t2011).\tRisk\tof\nrecurrence\tin\ta\tsubsequent\tpregnancy\tis\t25%\t(\nMyers,\t2017\n).\tRisk\tof\tpreeclampsia\tis\tless\tlikely\tin\nsubsequent\tpregnancies\twith\t... | [
-0.006024236790835857,
-0.010157921351492405,
0.02290046587586403,
-0.012089786119759083,
-0.09274731576442719,
0.03953718766570091,
0.021556226536631584,
0.012041973881423473,
-0.020139815285801888,
0.06714800745248795,
0.1692388653755188,
-0.03683463856577873,
-0.011893626302480698,
-0.0... |
partner.\nPreeclampsia\tinvolves\tdysfunction\tof\tmultiple\torgan\tsystems.\tIt\tis\tdynamic,\tprogressive,\n\tand\tonce\nevident,\tis\tnot\treversible.\tDelivery\tis\tneeded\tbecause\tit\tis\tpotentially\tfatal\tfor\tmother\tand\tbaby.\nGrowth\trestriction\tis\tcommon\tand\tbabies\tare\toften\talso\tpremature\tin\tan... | [
-0.015063479542732239,
-0.022539187222719193,
0.039571307599544525,
0.022876311093568802,
-0.14514032006263733,
0.045162271708250046,
0.09784793108701706,
-0.033275701105594635,
0.016308903694152832,
0.06422285735607147,
0.10215051472187042,
-0.03721509873867035,
0.0005636526038870215,
0.0... |
progressing\tto\tsevere\tpreeclampsia,\teclampsia\t(new\tonset\tgrand\tmal\tseizures),\tor\t\nHELLP\nsyndrome\n\t(hemolysis,\televated\tliver\tenzymes,\tand\tlow\tplatelets),\tall\tof\twhich\thave\thigh\trates\tof\nmaternal\n\tmorbidity\tand\tmortality\t(\nACOG,\t2019\n).\tThose\twomen\twith\tsuperimposed\tpreeclampsia... | [
0.0026149607729166746,
-0.028828298673033714,
0.012549678795039654,
-0.00718829408288002,
-0.10337809473276138,
-0.049079861491918564,
-0.005109203979372978,
0.05576862767338753,
-0.05861975625157356,
0.038661565631628036,
0.0710233524441719,
0.043456196784973145,
-0.01693805120885372,
0.0... |
ACOG,\t2019\n).\tThose\twomen\twith\tsuperimposed\tpreeclampsia\tonto\nchronic\thypertension\t(13%\tto\t40%\tof\twomen)\thave\tmuch\tworse\tconsequences\t(\nACOG,\t2013c\n).\nWomen\twith\tpreeclampsia\tthat\tdevelops\tnear\tterm\thave\tdouble\tthe\trisk\tof\tCVD\tlater\tin\tlife,\tbut\tthe\nrisk\tof\tCVD\tis\tnearly\t1... | [
-0.056073594838380814,
-0.0021974663250148296,
0.023704133927822113,
-0.03788682818412781,
-0.09947111457586288,
0.0029191533103585243,
0.04884635657072067,
0.04142318293452263,
-0.02725253999233246,
0.05145852640271187,
0.12944461405277252,
-0.028127674013376236,
0.06103915348649025,
-0.0... |
because\tof\tpreeclampsia\t(\nRoberts\tand\tBell,\t2013\n).\nPreeclampsia\thas\thistorically\tbeen\tdefined\tby\televated\tblood\tpressure\tand\tproteinuria,\tbut\nguidelines\tnow\trecommend\tnot\twaiting\tfor\tthe\tproteinuria\tto\tappear.\t\nBox\t14.4\n\tsummarizes\ndiagnostic\tcriteria\tdesigned\tto\tfacilitate\tear... | [
0.006126109976321459,
-0.046433914452791214,
0.03660086542367935,
-0.027576247230172157,
-0.009069464169442654,
-0.006054663099348545,
0.040443554520606995,
0.09444919228553772,
0.03175153583288193,
0.04361101984977722,
0.08915768563747406,
0.040137238800525665,
-0.010955795645713806,
0.08... |
BOX\t14.4\nPreeclampsia\tDiagnostic\tCriteria\nElevated\tblood\tpressure\nConfirmed\t≥160\tor\t≥110\tfor\tanyone\t(confirmed\n\tover\ta\tfew\tminutes)\tor\t≥140\tor\t≥90\nafter\t20\tweeks\tof\tgestation\t(confirmed\tover\t4\thours)\tif\tpreviously\tnormal\nAND\nProteinuria\n≥300\tmg/24-hour\turine\tcollection,\tan\text... | [
-0.037630777806043625,
0.02040165476500988,
0.05113356187939644,
0.02181980013847351,
-0.07782620191574097,
-0.0323144868016243,
0.06479285657405853,
0.045335911214351654,
0.02977435663342476,
0.0485004223883152,
0.04521482065320015,
-0.04404695704579353,
0.04726604372262955,
0.04700341448... |
protein/creatinine\tratio\t≥0.3,\tor\tdipstick\treading\tof\t2+\tif\tno\tother\tquantitative\tmethods\nare\tavailable\nOR\nElevated\tblood\tpressure\nConfirmed\t≥160\tor\t≥110\tfor\tanyone\t(confirmed\n\tover\ta\tfew\tminutes)\tor\t≥140\tor\t≥90\nafter\t20\tweeks\tof\tgestation\t(confirmed\tover\t4\thours)\tif\tpreviou... | [
-0.04602959752082825,
-0.13042254745960236,
0.009811352007091045,
-0.021630804985761642,
-0.07172847539186478,
-0.00249558687210083,
0.059327833354473114,
0.06094188988208771,
0.02869211696088314,
0.03370840102434158,
0.06750887632369995,
-0.006233379244804382,
0.062375184148550034,
0.0965... |
AND\nNew\tonset\tof\tany\tof\tthe\tfollowing:\nThrombocytopenia:\tplatelets\t<100,000/microliter\nRenal\tinsufficiency:\tserum\tcreatinine\t>1.1\tmg/dL\tor\tdoubling\tof\tserum\tcreatinine\nconcentration\tin\tabsence\tof\tother\trenal\tdisease\nImpaired\tliver\tfunction:\televated\tliver\ttransaminases\tto\ttwice\n\tno... | [
0.002650927985087037,
-0.08943954855203629,
-0.0056619648821651936,
-0.04943382740020752,
-0.09396403282880783,
-0.03344011306762695,
0.08847661316394806,
0.05389946326613426,
0.00984324049204588,
0.05144873633980751,
0.11835846304893494,
-0.003302474971860647,
0.05041946470737457,
0.02918... |
normal\tblood\nconcentrations\nPulmonary\tedema\nCerebral\tor\tvisual\tsymptoms\nAdapted\tfrom\tAmerican\tCollege\tof\tObstetricians\tand\tGynecologists\t(ACOG):\tACOG\tPractice\tBulletin\tNo.\n202:\tGestational\tHypertension\tand\tPreeclampsia,\tObstet\tGynecol\t133:e1,\t2019.\nThe\tcauses\tof\tpreeclampsia\tare\tunde... | [
-0.0007667922764085233,
-0.0402919203042984,
0.07149717956781387,
0.0008586383773945272,
-0.10810716450214386,
0.00903971865773201,
0.023321224376559258,
0.00868756789714098,
-0.023919997736811638,
0.05440033599734306,
0.1261928826570511,
-0.05733424425125122,
0.016408883035182953,
0.01341... |
with\ta\tpoorly\tperfused\tplacenta\n\t(from\tfailed\tremodeling\tof\tthe\tmaternal\tspiral\tarteries)\tbeing\tthe\nroot\tcause\t(\nACOG,\t2013c\n).\tReduced\tperfusion\tand\tincreased\tvelocity\tof\tblood\tperfusing\tthe\nintervillous\tspaces\talters\tplacental\tfunction\tand\tleads\tto\tmaternal\tdisease\tthrough\tox... | [
-0.004520808812230825,
-0.03806734085083008,
0.061042770743370056,
-0.021634165197610855,
-0.07725303620100021,
0.012866711243987083,
0.05778918042778969,
0.008516017347574234,
0.05238277465105057,
0.0802641436457634,
0.03560865670442581,
-0.03300466015934944,
-0.0038236246909946203,
0.049... |
endoplasmic\treticulum\tstress\tand\tinflammation,\tas\twell\tas\tmodified\tendothelial\tfunction\tand\nangiogenesis.\tThe\tsecond\tstage,\tcalled\t\nmaternal\tsyndrome,\n\tis\ta\tcascade\tof\tevents,\tbut\twhat\tlinks\tthe\nhypoxic\tplacenta\tand\tthe\tmaternal\tsyndrome\tis\tunclear\tand\tpossibly\tinvolves\toxidativ... | [
0.052657660096883774,
-0.06767291575670242,
0.04772025719285011,
-0.030665472149848938,
-0.10532715916633606,
0.025150861591100693,
0.07281219214200974,
0.027278898283839226,
-0.0009592730202712119,
0.09427163004875183,
0.07300252467393875,
-0.022819703444838524,
-0.032403282821178436,
0.0... |
hypertension\tand\tproteinuria\tare\tonly\ta\tsmall\tpart\tof\tthe\tsyndrome\tand\treduced\tperfusion\tof\tany\norgan\tin\tthe\tbody\tcan\tlead\tto\themorrhage\tand\tnecrosis.\tNot\tall\twomen\twith\tinadequate\tplacental\nperfusion\tdevelop\tpreeclampsia.\tA\twoman’s\tunderlying\tdisease\n\t(e.g.,\tdiabetes,\thyperten... | [
-0.003862307872623205,
-0.03873336315155029,
0.02387622557580471,
-0.0023533497005701065,
-0.03578748553991318,
0.007691462058573961,
0.00428070779889822,
0.09753427654504776,
-0.054654575884342194,
0.05373838543891907,
0.057120874524116516,
-0.005548146087676287,
-0.01944388821721077,
0.0... |
(e.g.,\tdiabetes,\thypertension),\nlifestyle\t(e.g.,\tobesity,\tactivity,\tsleep),\tgenetics,\tand\tenvironmental\tconditions\t(e.g.,\tair\tpollution)\tmay\naffect\tthe\tmaternal\tresponse\t(\nRoberts\tand\tBell,\t2013\n).\tThe\tinflammatory\tresponse\tis\taccentuated\tin\npreeclampsia.\tPredictive\ttests\tare\tbeing\t... | [
0.00981925055384636,
-0.02663533017039299,
0.07765723764896393,
-0.0363159105181694,
-0.07164744287729263,
0.01610870473086834,
0.06881573051214218,
-0.039847854524850845,
0.00028100472991354764,
0.07192844897508621,
0.06619992852210999,
-0.053888894617557526,
0.02731582708656788,
0.008675... |
ACOG,\t2019\n).\tIt\tis\nnow\tthought\tthat\tpreeclampsia\tis\tactually\ta\tsyndrome\n\tof\tmany\tdiseases\twith\tsubsets\tof\npathophysiology\tand\tvaried\tcontributions\tof\tmaternal\tand\tplacental\tfactors\t(\nRoberts\tand\tBell,\t2013\n).\nPrevention\tof\tpreeclampsia\thas\tnot\tyet\tbeen\teffective,\talthough\tda... | [
0.008058364503085613,
-0.023476319387555122,
0.06541291624307632,
0.0003960576141253114,
-0.07050450891256332,
0.04189695790410042,
0.05737397074699402,
-0.007184244692325592,
-0.010733062401413918,
0.044312573969364166,
0.1414237767457962,
-0.03513433039188385,
0.01301734708249569,
0.0049... |
beneficial\t(\nACOG,\t2019\n).\tAlthough\tpreviously\trecommended,\tvitamin\tC\tand\tE\tsupplements\tdo\tnot\nprevent\toccurrence\tof\tpreeclampsia\tor\tadverse\toutcomes\tand\tmay\tbe\tassociated\n\twith\tincreased\trisk\nof\tgestational\thypertension\tand\tLBW.\tCalcium\tsupplementation\tmay\thelp\treduce\tsymptom\ts... | [
0.005688571371138096,
-0.0009880560683086514,
0.0638631135225296,
-0.017924683168530464,
-0.05411010608077049,
0.06893453001976013,
0.07607944309711456,
0.020452290773391724,
-0.022035028785467148,
0.09828928112983704,
0.12395283579826355,
0.022143034264445305,
0.014004681259393692,
0.0309... |
a\tmother’s\tbaseline\tcalcium\tintake\thas\tbeen\tless\tthan\t600\tmg/day\t(\nACOG,\t2013c\n).\tThere\tis\ninsufficient\tevidence\tto\tdemonstrate\teffectiveness\tof\tfish\toil,\tgarlic,\tvitamin\tD\tor\tfolic\tacid\nsupplementation,\tnor\tof\tsodium\trestriction\t(\nACOG,\t2019\n).\tAvoiding\texcessive\tweight\tgain\... | [
-0.02961103245615959,
-0.05482156202197075,
0.06884604692459106,
0.018347585573792458,
-0.11256200075149536,
-0.0165440384298563,
0.06633049249649048,
0.02370498515665531,
-0.02904079295694828,
0.02241676300764084,
0.1048654168844223,
-0.07167001068592072,
0.014454126358032227,
0.017902990... |
ACOG,\t2019\n).\tAvoiding\texcessive\tweight\tgain\tand\ttightly\ncontrolling\tdiabetes\tmay\thelp.\tProtein\tand\tcalorie\trestriction\tfor\twomen\twith\tobesity\tdoes\tnot\nreduce\tthe\trisk\tof\teither\tgestational\thypertension\tor\tpreeclampsia\tand\tmay\tincrease\tthe\trisk\tof\nIUGR.\tBed\trest\tdoes\tnot\tappea... | [
-0.024569444358348846,
-0.039294809103012085,
0.07215014845132828,
0.011476411484181881,
-0.08860643208026886,
-0.005343697965145111,
0.10385922342538834,
0.013324318453669548,
-0.045128948986530304,
0.05017346888780594,
0.10539757460355759,
-0.023810062557458878,
0.04056830704212189,
-0.0... |
(30\tminutes/day)\tis\trecommended\tas\tduring\tnormal\tpregnancy,\tbut\tit\tis\tunclear\twhether\tit\tcan\thelp\nreverse\tthe\n\tendothelial\tdysfunction\tand\tprevent\tadverse\tpregnancy\toutcomes.\tObesity,\tleptin,\ninsulin,\tand\tfree\tfatty\tacids\tappear\tto\taffect\tvarious\tstages\tof\tpreeclampsia.\tEndotheli... | [
-0.032632797956466675,
-0.0588984452188015,
0.016419557854533195,
0.0060084545984864235,
-0.07738301903009415,
-0.0009707259596325457,
0.031973473727703094,
0.07780130207538605,
-0.05515716224908829,
0.04763992875814438,
0.07596415281295776,
0.001993500394746661,
-0.02137157693505287,
-0.0... |
from\tplacental\tischemia\tand\thypoxia\tappear\timportant.\tAn\timbalance\tof\tangiogenic\tfactors,\timmune\nfactors,\tinflammation,\tendothelin\t(a\tprotein\tthat\tconstricts\tblood\tvessels),\tnitric\toxide,\toxidative\tand\nendoplasmic\n\treticulum\tstress,\tthe\tstress\tresponse\tgene\themeoxygenase\tand\tits\tcat... | [
0.004459199961274862,
-0.08968938142061234,
0.0065244948491454124,
-0.02143128030002117,
-0.03378470242023468,
0.04986456409096718,
0.07057195901870728,
0.06585095822811127,
-0.006903868168592453,
0.09269186109304428,
0.07907061278820038,
-0.06205194815993309,
0.0011415034532546997,
0.0533... |
carbon\tmonoxide,\tand\tthe\teffect\tof\tstatins\tare\tall\tbeing\tstudied.\nFor\tthose\twomen\twith\ta\thistory\tof\tpreeclampsia,\tweight\tloss,\tincreased\tphysical\tactivity,\tsmoking\ncessation,\tand\toptimization\tof\tblood\tglucose\tlevels\tand\tnutrient\tintakes\tpreconceptually\tare\nrecommended.\tDuring\tpreg... | [
0.005321284290403128,
-0.019111383706331253,
0.06777451932430267,
0.08440040796995163,
-0.04489964246749878,
0.031455013900995255,
0.06260669231414795,
0.023681482300162315,
-0.066222183406353,
0.0731605663895607,
0.10700314491987228,
-0.07112941145896912,
-0.006433278787881136,
-0.0140294... |
normal\trate\tof\tweight\tgain,\twith\noptimal\tcalcium\tintake\tand\tfruits\tand\tvegetables\t(antioxidants),\tmay\tbe\tbeneficial.\tEncourage\nnotifying\tthe\tmedical\tprovider\timmediately\tif\tthere\tis\ta\tsudden\tonset\tof\tface\tor\thand\tswelling,\npersistent\theadaches,\tseeing\tspots\tor\tchanges\tin\teyesigh... | [
0.00971840787678957,
-0.036851778626441956,
0.06773289293050766,
-0.0026201726868748665,
-0.08919523656368256,
-0.012181628495454788,
0.07194327563047409,
-0.009823978878557682,
-0.017495112493634224,
0.05606986582279205,
0.12439478933811188,
-0.08105975389480591,
0.041767820715904236,
0.0... |
stomach,\tnausea\tand\tvomiting\tin\tthe\tsecond\thalf\tof\tpregnancy,\trapid\tweight\tgain,\n\tor\tdifficulty\nbreathing.\nAlthough\tdelivery\tresolves\tthe\tpreeclampsia\tfor\tmost,\ta\tsubset\tof\twomen\thave\ta\tworsening\tof\npreeclampsia\tafter\tdelivery\tand\tothers\tmay\tfirst\tdevelop\tpreeclampsia\tpostpartum... | [
0.01939493976533413,
-0.0380592904984951,
0.026363693177700043,
0.030161786824464798,
-0.08808666467666626,
-0.016211997717618942,
0.048701487481594086,
0.01520488690584898,
-0.0787816271185875,
0.054972775280475616,
0.11594226211309433,
-0.018834559246897697,
-0.00539541756734252,
-0.0463... |
syndrome.\tPain\tmedications\tmay\thave\tto\tbe\tmodified.\tBlood\tpressure\tmay\tbe\tlabile\tfor\tmonths\tbut\nusually\tnormalizes\tby\t1\tyear\tpostpartum.\tPostpartum\thypertension\tmay\tpredict\tfuture\n\tchronic\nhypertension\t(\nACOG,\t2013c\n).\nNausea\tand\tvomiting,\thyperemesis\tgravidarum,\tand\tptyalism\nMo... | [
-0.009528483264148235,
-0.03252938389778137,
0.019620036706328392,
0.018132656812667847,
-0.05150981619954109,
0.016126738861203194,
0.031414154917001724,
0.058263540267944336,
-0.0372159481048584,
0.05388971045613289,
0.10502637177705765,
-0.0008463666308671236,
0.01667116768658161,
-0.01... |
Morning\tsickness,\t\nnausea\tand\tvomiting\tin\tpregnancy\t(NVP)\n,\taffects\t50%\tto\t90%\tof\tall\tpregnant\nwomen\tduring\tthe\tfirst\ttrimester\tand\tusually\tresolves\tby\t20\tto\t22\tweeks\tof\tgestation,\talthough\tup\tto\n10%\tof\twomen\tsuffer\twith\tit\tuntil\tdelivery\t(\nBustos\tet\tal,\t2017\n).\tThe\tcau... | [
0.005361513700336218,
0.03571821376681328,
0.11773993819952011,
0.012621372938156128,
-0.03284556791186333,
0.032817356288433075,
0.09470129758119583,
-0.004662021528929472,
-0.01703600399196148,
0.014471225440502167,
0.03677578270435333,
-0.038124773651361465,
-0.0013462824281305075,
0.00... |
Bustos\tet\tal,\t2017\n).\tThe\tcause\tof\tNVP\tis\tunclear\tbut\tlikely\nincludes\ta\tgenetic\tpredisposition,\tcombined\twith\tchanges\tin\thuman\tchorionic\tgonadotropin\t(hCG),\nestrogen,\tand\tprogesterone\tlevels.\tRecently\tan\tincrease\tin\tthe\thalf-life\tof\tendokinin\tB,\ta\ttachykinin\nproduced\tby\tthe\tpl... | [
-0.03542893007397652,
-0.035926856100559235,
0.03290240094065666,
-0.004869204945862293,
-0.04931211099028587,
0.0438825748860836,
0.06702329218387604,
0.03980674222111702,
0.008076461963355541,
0.05286656320095062,
0.11386021971702576,
-0.04252368211746216,
0.005722254514694214,
0.0094778... |
Lowry\tand\nWoods,\t2018\n)\tbecause\tit\talso\tstimulates\tthe\tNK1R\treceptor\tin\tthe\tbrain,\tcausing\tnausea\tand\nvomiting\tin\tsome\n\twomen.\tNVP\tmay\tbe\tmediated\tthrough\tthe\tvestibuloocular\treflex\tpathway\tand\nthose\twith\ta\thistory\tof\tmotion\tsickness\tor\tmigraines\tare\tat\tincreased\trisk.\tThos... | [
0.00630358187481761,
-0.08763734996318817,
-0.013004676438868046,
-0.07355658710002899,
-0.09874837100505829,
0.011917218565940857,
0.07539913803339005,
-0.03670942783355713,
-0.012956365011632442,
0.0678737685084343,
0.09546962380409241,
-0.02537994645535946,
0.02001821994781494,
-0.00530... |
female\tfetus,\tmultiple\tfetuses,\tor\ta\tmolar\tpregnancy\t(sperm\tfertilizes\tan\tempty\tegg,\tresulting\tin\tno\nembryo\tbut\ta\tplacenta\tthat\tdevelops\tinto\tan\tabnormal\tmass\tof\tcells)\tare\tmore\tlikely\tto\tsuffer\twith\neither\tNVP\tor\thyperemesis\n\tgravidarum,\tas\tare\tthose\twith\thyperthyroid\tdisor... | [
-0.02696159854531288,
0.00910267885774374,
0.035022199153900146,
-0.014973614364862442,
-0.05798088759183884,
0.013061055913567543,
0.08841785043478012,
0.0019472521962597966,
-0.014330276288092136,
0.08535808324813843,
0.12648510932922363,
-0.037966933101415634,
0.01875634677708149,
-0.01... |
gravidarum,\tas\tare\tthose\twith\thyperthyroid\tdisorders,\tGI\tdisorders,\npreexisting\tdiabetes,\tor\ta\tpsychiatric\tillness.\tMaternal\tage\tmore\tthan\t30\tyears\tand\tsmoking\tare\nprotective,\tbut\tpaternal\tsmoking\tincreases\trisk\t(\nFejzo\tet\tal,\t2012\n).\tNVP\tis\tassociated\twith\tmore | [
-0.014357181265950203,
-0.030538123100996017,
0.06843069940805435,
-0.03195589408278465,
-0.07948886603116989,
0.0027911944780498743,
0.11131158471107483,
0.013033449649810791,
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0.061828140169382095,
0.10091912001371384,
-0.052203476428985596,
-0.0018076874548569322,
... |
Fejzo\tet\tal,\t2012\n).\tNVP\tis\tassociated\twith\tmore\nfavorable\tpregnancy\toutcomes,\tincluding\tfewer\tbirth\tdefects;\treduced\trisk\tof\tmiscarriage,\tpreterm\ndelivery,\tor\tstillbirth;\tand\tgreater\n\tbirth\tweight.\nTreatment\tfor\tNVP\tinvolves\tmanaging\tthe\tsymptoms.\tMotion,\tspecific\todors,\tloud\tn... | [
-0.026241857558488846,
0.013328351080417633,
0.008468396961688995,
0.037462711334228516,
-0.08271133899688721,
0.02687264420092106,
0.08538180589675903,
0.02805919572710991,
-0.013885258696973324,
0.07013145834207535,
0.13541468977928162,
-0.006472080480307341,
0.011560874059796333,
0.0151... |
flickering\tlights,\tand\tadverse\tclimate\tconditions\tmay\ttrigger\tthe\tnausea.\tFortunately,\tmost\twomen\nwith\tNVP\tare\tfunctional,\table\tto\twork,\tdo\tnot\tlose\tweight,\tand\tare\thelped\tby\tsimple\tdietary\nmeasures.\tMany\tdietary\tand\tlifestyle\trecommendations\thave\tnot\tbeen\tevaluated\tin\tthe\tlite... | [
-0.0070536015555262566,
-0.0314161516726017,
0.07998063415288925,
-0.02886497788131237,
-0.07942067831754684,
-0.011095218360424042,
0.07869963347911835,
0.0063913604244589806,
0.007275334093719721,
0.059645768254995346,
0.08810146898031235,
-0.05751343443989754,
0.020564738661050797,
0.01... |
(\nKaiser\tand\tCampbell,\t2014\n).\tAlthough\tthe\tquality\tof\tthe\tevidence\tis\tlow,\tit\tappears\tthat\tginger\npreparations\t(tablets,\tsyrup,\tcapsules,\tor\tginger\tbiscuits)\tare\tmore\teffective\tthan\tplacebos\tin\nreducing\tthe\tseverity\tof\tsymptoms\t(\nO’Donnell\tet\tal,\t2016\n),\tpossibly\tby\tmultiple... | [
-0.02056826837360859,
-0.01846473291516304,
0.0759335607290268,
-0.07589109241962433,
-0.12226956337690353,
0.012909685261547565,
0.07923050224781036,
-0.03237529098987579,
0.0307146143168211,
0.05452554300427437,
0.09623080492019653,
-0.023741545155644417,
0.05079827457666397,
0.025425424... |
),\tpossibly\tby\tmultiple\tmechanisms\t(\nMarx\tet\nal,\t2017\n).\tHowever,\twhile\tginger\treduces\tthe\tnausea,\tit\tmay\tnot\treduce\tthe\tepisodes\tof\temesis\tand\ndoes\tnot\twork\tfor\tmany\tpeople,\tespecially\n\tthose\twith\thyperemesis\t(\nDean\tand\tO’Hara,\t2015\n).\tGinger\nsupplements\tcan\tbe\toffered\ta... | [
-0.014533404260873795,
0.018571164458990097,
0.056517090648412704,
-0.045295558869838715,
-0.07935027033090591,
-0.05122504010796547,
0.0582101084291935,
-0.02261965535581112,
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0.09143348783254623,
0.1100214496254921,
-0.030017077922821045,
0.08781653642654419,
0.022... |
ACOG,\t2018b\n)\tbut\nshould\tnot\tbe\tused\tfor\twomen\ton\tanticoagulation\ttherapy\tbecause\tof\tthe\tincreased\trisk\tof\tbleeding\nwith\tplatelet\tfunction\tinhibition\t(\nBustos\tet\tal,\t2017\n).\tGinger\thas\talso\tbeen\treported\tto\tincrease\nsymptoms\tfor\tsome,\tincluding\theartburn\tand\tthroat\tburning\n\... | [
-0.002381271217018366,
0.011817436665296555,
0.05080314353108406,
-0.032883431762456894,
-0.09596359729766846,
-0.023962995037436485,
0.08247345685958862,
-0.041298191994428635,
-0.04021206125617027,
0.05834462493658066,
0.10835441201925278,
-0.07660461962223053,
0.05815516784787178,
0.017... |
2015\n).\tIf\tthe\tsymptoms\tare\talready\tsevere,\tginger\tis\tunlikely\tto\tbe\thelpful\tand\ttherefore\tdelays\tmore\neffective\ttreatment.\nAcupressure\tof\tthe\tP6\tpoint\tof\tthe\twrist\tmay\thave\tlimited\tbenefit\tbut\tneither\tacupuncture\tnor\nelectrical\tnerve\tstimulation\tappear\tto\tbe\teffective\t(\nACOG... | [
0.0033056919928640127,
-0.03538130968809128,
0.10690051317214966,
0.003945460077375174,
-0.07042143493890762,
0.04537327215075493,
0.030966032296419144,
-0.017859384417533875,
-0.0014557322720065713,
0.04452769085764885,
0.11066479980945587,
-0.051879480481147766,
0.030346982181072235,
0.0... |
ACOG,\t2018b\n).\tNoise\treduction\tand\thypnosis\talso\ncan\tbe\thelpful.\tIf\tnot\ttolerated,\tstopping\n\tthe\tprenatal\tvitamins\tmay\thelp,\tbut\twomen\tshould\tcontinue\nthe\tsupplemental\tfolic\tacid\tif\tpossible,\tand\toften\ttaking\tthe\tprenatal\tvitamins\tbefore\tbed\tor\twith\tfood | [
0.02238411456346512,
-0.042957570403814316,
0.06198745220899582,
-0.03872966393828392,
-0.06929897516965866,
0.002511511789634824,
0.0722057893872261,
-0.04861001297831535,
0.001577260671183467,
0.06757649779319763,
0.12296596169471741,
-0.0506003238260746,
0.05259936675429344,
-0.00743940... |
during\tthe\tlargest\tmeal\tof\tthe\tday\tis\ttolerated.\tOthers\trecommend\tadding\tsupplemental\tthiamin\t(at\nleast\t5\tmg/day)\tto\tlower\tthe\trisk\tof\tWernicke’s\tencephalopathy\t(\nFejzo\tet\tal,\t2016\n).\tVarious\nantinausea\tmedications\tare\talso\tavailable,\twith\n\tdifferent\tmodes\tof\taction\tand\trisk\... | [
-0.0244307704269886,
-0.0405893437564373,
0.06625433266162872,
-0.04270513355731964,
-0.06618336588144302,
0.01380311418324709,
0.1111745834350586,
0.04985840246081352,
-0.04200610890984535,
0.03622272610664368,
0.0737384781241417,
0.004907678812742233,
0.08299063891172409,
0.0724088624119... |
6\n,\nin\tcombination\twith\tdoxylamine,\tis\toften\tused\t(\nACOG,\t2018b\n).\tWhether\tthe\tvitamin\tB\n6\n\talone\tis\neffective\tas\twell\tas\twhat\tform\tof\tthe\tB\n6\n\tis\tbest\tare\tboth\tunclear\tbut\tit\tappears\tthat\tthe\tmetabolites\npyridoxine\tand\tpyridoxal\tmay\tfunction\tas\tprodrugs\t(\nMatok\tet\ta... | [
-0.012296311557292938,
-0.07676270604133606,
0.031093556433916092,
-0.03765661269426346,
-0.05962764471769333,
0.056480102241039276,
0.03679496794939041,
0.032117899507284164,
-0.013741295784711838,
0.047582097351551056,
0.06892070919275284,
-0.011232990771532059,
0.014679908752441406,
-0.... |
Matok\tet\tal,\t2014\n).\tMarijuana,\twhile\tit\tis\npromoted\tby\tsome\tto\thelp\twith\tNVP,\tis\tnot\trecommended\n\t(\nACOG,\t2018b\n).\tIn\tfact,\tcannabinoid\nhyperemesis\tsyndrome,\tpotentially\tfatal,\thas\tbeen\tdocumented\t(\nNourbakhsh\tet\tal,\t2018\n).\nSmall,\tfrequent\tsnacks\tof\tcarbohydrate\tfoods,\tin... | [
0.009508696384727955,
-0.025597281754016876,
0.010570733807981014,
-0.03907505422830582,
-0.0999399870634079,
-0.004085023421794176,
0.07785990089178085,
0.04144025966525078,
-0.00997677817940712,
0.037462420761585236,
0.10524051636457443,
-0.05394609645009041,
0.039689987897872925,
0.0141... |
some,\twhereas\tprotein\tfoods\tmay\thelp\tothers\t(\nErick,\t2014\n).\tSome\twomen\tcrave\tpotato\tchips.\tSome\ndo\tnot\ttolerate\todors\tand\tare\tbothered\tby\thot\tfoods,\tpreferring\tfoods\tthat\tare\n\tcold\tor\tat\troom\ntemperature.\tSmelling\tlemons\tmay\thelp\tblock\tnoxious\todors.\tAvoiding\thunger\tby\tea... | [
-0.002038974082097411,
-0.029804985970258713,
0.061425525695085526,
-0.006809384562075138,
-0.0644664317369461,
0.0184136051684618,
0.07349367439746857,
-0.03864026442170143,
-0.007605012971907854,
0.05293554440140724,
0.14603397250175476,
-0.0543493889272213,
0.0378122553229332,
-0.009851... |
frequently\toften\thelps,\tas\tdoes\tseparating\tdry\tfoods\tfrom\tliquids.\tAvoiding\thighly\tspiced\tfoods\tor\nbitter\tfoods\tis\thelpful\tfor\tsome,\tbut\tfor\tothers\ttaste\tsensitivity\tdecreases\tand\tstrong\tflavors\tare\ncraved.\tWomen\tshould\tavoid\todors\tor\tsituations\tthat\ttrigger\tsymptoms\tand\tshould... | [
0.017896274104714394,
-0.05977414548397064,
0.04312947764992714,
0.022416459396481514,
-0.038840971887111664,
-0.018199939280748367,
0.09978383034467697,
-0.007776634301990271,
-0.045629896223545074,
0.04535134136676788,
0.10739947110414505,
-0.049094755202531815,
0.049438804388046265,
0.0... |
reduces\n\tthe\tnausea\tsensation.\tUnfortunately,\tthere\tis\tno\tcure-all.\tHowever,\treminding\tthe\tmother\nthat\tthis\tis\ta\tgood\tsign\tfor\tthe\tpregnancy\t(i.e.,\tthe\tbody\tis\tresponding\tas\tit\tshould),\tand\tthat\tit\t\nwill\nend,\toften\treassures\ther\tand\tlowers\tthe\tworry\tand\tstress,\tthus\thelpin... | [
0.04347913712263107,
0.047032907605171204,
0.12310383468866348,
-0.03827914595603943,
-0.052282076328992844,
0.03900383040308952,
0.0989941954612732,
0.01232262421399355,
0.03212267532944679,
0.09161918610334396,
0.10150977969169617,
0.007620947435498238,
0.05374312400817871,
0.01091129519... |
When\tearly\tpregnancy\tis\tcharacterized\tby\texcessive\tvomiting\t(severity\tis\toften\testimated\tby\tthe\nPUQE\tscore:\t\np\nregnancy-\nu\nnique\t\nq\nuantification\tof\t\ne\nmesis)\tand\tweight\tloss\t(often\tat\tleast\t5%\nprepregnant\tweight),\tusually\twith\tdehydration,\telectrolyte\timbalances\tcan\toccur.\tH... | [
-0.004097640048712492,
-0.0262380912899971,
0.019145259633660316,
0.059842001646757126,
-0.05012935400009155,
-0.010105259716510773,
0.06348638981580734,
0.08873022347688675,
-0.01802019402384758,
-0.001870627049356699,
0.0646677017211914,
-0.026032187044620514,
0.007721798960119486,
0.003... |
sickness”\tbecomes\t\nhyperemesis\tgravidarum\t(HG)\n.\tThe\tprevalence\tof\tHG\tis\t0.3%\tto\t3%\tof\npregnancies\t(\nACOG,\t2018b\n)\tand\tis\tthe\tmost\tfrequent\tcause\tof\thospital\tadmissions\tearly\tin\npregnancy,\tincreasing\tboth\tworry\tand\tthe\teconomic\tburden.\tRisk\n\tfactors\tare\tthe\tsame\tas\tthose\t... | [
0.027298789471387863,
-0.02829759195446968,
0.04850507900118828,
0.014528888277709484,
-0.07976987957954407,
0.0018529754597693682,
0.09144143760204315,
0.054138097912073135,
-0.0048542809672653675,
0.03396599367260933,
0.12938207387924194,
-0.03395894169807434,
0.019791657105088234,
-0.02... |
NVP.\tRecurrence\trate\tin\ta\tsubsequent\tpregnancy\tis\t15%\tto\t81%\t(\nGrooten\tet\tal,\t2016\n),\twith\thigher\nestimates\tfrom\tsurveys\tin\twhich\tsymptoms\tare\treported\trather\tthan\tthose\tjust\tlooking\tat\thospital\nadmissions.\tEarly\ttreatment\tof\tNVP,\tincluding\teven\tpreemptive,\tis\tthought\tto\thel... | [
-0.007599719800055027,
-0.01471065916121006,
0.053632691502571106,
-0.044392429292201996,
-0.11464093625545502,
-0.014845133759081364,
0.04311838746070862,
0.0289761945605278,
0.009612072259187698,
0.048351217061281204,
0.11561702191829681,
-0.016750581562519073,
0.03339938446879387,
0.013... |
progression\tto\tHG\t(\nACOG,\t2018b\n).\nFetal\tcomplications\tof\tHG\tvary\tbut\tinclude\tpoor\n\tfetal\tgrowth\tand\tpreterm\tdelivery.\tThere\tis\tan\nincreased\trisk\tof\tfetal\tloss\twith\tgestational\tmalnutrition,\tas\thigh\tas\t37%\tspontaneous\tfetal\tloss\trate\namong\twomen\twith\tsignificant\tweight\tloss\... | [
0.023439085111021996,
-0.023763926699757576,
0.030650874599814415,
0.007836581207811832,
-0.08266859501600266,
0.0206182599067688,
0.04106158763170242,
0.05828423798084259,
-0.060661714524030685,
0.0535278245806694,
0.10390260070562363,
-0.013154222629964352,
0.03719839081168175,
0.0011666... |
Chiossi\tet\tal,\t2006\n).\nWhile\tdocumented\tcongenital\tanomalies\tare\trare,\tchondrodysplasia\tpunctata\tresulting\tfrom\nmaternal\tvitamin\tK\tdeficiency\thas\tbeen\tdocumented\t(\nErick,\t2014\n).\tResearch\thas\tshown\tthese\nexposed\tchildren\thave\ta\t3.28-fold\tincrease\tin\tthe\todds\tof\treceiving\ta\tneur... | [
-0.03964667767286301,
-0.015016121789813042,
0.09152234345674515,
-0.023290535435080528,
-0.1259007304906845,
-0.014586695469915867,
0.049887336790561676,
0.009403378702700138,
-0.03798653557896614,
0.11871989071369171,
0.1438339501619339,
-0.06729929894208908,
-0.003904054407030344,
0.028... |
including\tattention\tor\tsensory\tdisorders\tand\tspeech,\tlanguage,\tand\tlearning\tdelays,\tespecially\tif\tthe\nHG\tstarted\tbefore\t5\tweeks\tof\tgestation\t(\nFejzo\tet\tal,\t2015\n).\tLower\tinsulin\tsensitivity\tin\tchildren\nexposed\tto\tHG\thas\talso\tbeen\tseen\t(\nAbramowitz\tet\tal,\t2017\n).\tMaternal\tco... | [
0.024305293336510658,
-0.012188099324703217,
0.07148350775241852,
-0.05127136781811714,
-0.08117423206567764,
0.02523926831781864,
0.07686050981283188,
-0.018331341445446014,
-0.0022562523372471333,
0.07661563158035278,
0.09429175406694412,
-0.019524943083524704,
0.04331038147211075,
0.082... |
Abramowitz\tet\tal,\t2017\n).\tMaternal\tcomplications\n\tinclude\textreme\nfatigue,\tdehydration,\tand\tmalnutrition.\tHG\tis\tassociated\twith\tguilt\tand\ta\tloss\tof\tself,\toften\twith\ta\nsense\tof\tdying,\tas\twell\tas\twith\tsocial\tisolation.\tIt\tis\tassociated\twith\tincreased\tdepression\tand/or | [
0.05898810178041458,
-0.03338363394141197,
0.03277746960520744,
0.0035428383853286505,
-0.08765421062707901,
0.04961708188056946,
0.12446349859237671,
-0.01290110219269991,
-0.02058381959795952,
0.06424884498119354,
0.07847918570041656,
-0.057122841477394104,
0.017013005912303925,
0.030847... |
anxiety\tbut\tthe\tdirection\tof\tthe\trelationship\tis\tcontroversial\tand\tstigmatizing\tthe\tmother\tis\tnot\nhelpful\t(\nDean\tet\tal,\t2018\n).\tOther\tcomplications\tmay\tinclude\tsplenic\tavulsion\t(spleen\n\tis\ttorn\tfrom\tits\nnormal\tlocation,\tresulting\tin\tan\temergency\tsituation\tdue\tto\texcessive\tble... | [
0.06127665564417839,
-0.07460228353738785,
0.0764901265501976,
0.05383392423391342,
-0.10861481726169586,
-0.004939057398587465,
0.11872545629739761,
-0.0043924166820943356,
0.0012743505649268627,
-0.007465259172022343,
0.05223342776298523,
-0.024403616786003113,
0.043243419378995895,
0.01... |
diaphragmatic\ttears,\tpneumothorax,\tValsalva\tretinopathy,\thypocalcemia,\tliver\tdysfunction,\tacute\nrenal\tfailure,\trhabdomyolysis,\tcentral\tpontine\tmyelinolysis,\tand\tdelirium,\tas\twell\tas\tmaternal\nposttraumatic\tstress\tsyndrome\tand\thigh\trisk\tof\tpregnancy\ttermination\twhen\tmanagement\tof\n\tHG\nfa... | [
0.013639523647725582,
-0.009792693890631199,
0.037197045981884,
-0.026866791769862175,
-0.0547013059258461,
-0.009439242072403431,
0.04291887953877449,
0.07390639185905457,
-0.03866129741072655,
0.04367157444357872,
0.018916873261332512,
0.0496935173869133,
0.07502858340740204,
0.041781231... |
HG\nfails\t(\nErick,\t2014\n;\t\nFejzo\tet\tal,\t2012\n;\t\nDean\tet\tal,\t2018\n;\t\nACOG\t2018b\n;\t\nAbramowitz\tet\tal,\t2017\n).\nMaternal\tdeaths\tassociated\twith\tHG\thave\tbeen\treported\t(\nFejzo\tet\tal,\t2016\n).\tDifficulty\tproducing\nbreastmilk\tand\tbonding\talso\tmay\thave\tto\tbe\taddressed. | [
-0.003651702543720603,
0.048617757856845856,
0.05180412530899048,
-0.037004150450229645,
-0.10386533290147781,
0.0646081268787384,
0.022715583443641663,
-0.036574024707078934,
-0.04192022606730461,
0.04186851531267166,
0.1300119310617447,
-0.01785121113061905,
-0.00033688213443383574,
0.00... |
breastmilk\tand\tbonding\talso\tmay\thave\tto\tbe\taddressed.\nHospitalization\tfor\tnutrition\tsupport\tand\thydration\tusually\tis\tindicated\tfor\tHG.\tManagement\tgoals\ninclude\tappropriate\tweight\tgain\tfor\tpregnancy,\tcorrection\n\tof\tfluid\tand\telectrolyte\tdeficits,\tavoidance | [
-0.0007334962720051408,
-0.020135413855314255,
0.036053553223609924,
0.013173253275454044,
-0.02853526547551155,
0.010906821116805077,
0.09495601058006287,
0.034908901900053024,
-0.05096839368343353,
0.01746520958840847,
0.10403041541576385,
-0.020294487476348877,
-0.011334763839840889,
-0... |
of\tfluid\tand\telectrolyte\tdeficits,\tavoidance\nof\tketosis,\tcontrol\tof\tHG\tsymptoms,\tand\tachievement\tof\tnitrogen,\tvitamin,\tand\tmineral\tbalance.\nBecause\tpregnancy\tis\ta\tcondition\tof\taccelerated\tstarvation,\trefeeding\tsyndrome\tis\tseen\toften,\nespecially\twith\tthe\tprovision\tof\tsimple\tdextros... | [
0.018926212564110756,
-0.05888504907488823,
-0.018201559782028198,
-0.05106804519891739,
-0.03732813522219658,
-0.021797165274620056,
0.11983997374773026,
0.11896810680627823,
0.009141907095909119,
0.037181586027145386,
0.07437548786401749,
0.01412020530551672,
0.01682295836508274,
0.06608... |
magnesium,\tand\tpotassium\tmust\tbe\tevaluated\tdaily\tbecause\tlow\tlevels\n\tmay\tresult\tin\tcardiac\nirregularities\tand\trespiratory\tfailure\t(see\t\nChapter\t12\n).\tAnother\tpotentially\tserious\tcomplication\tis\nWernicke’s\tencephalopathy,\twith\tat\tleast\t63\tcases\tbeing\treported\tworldwide\t(\nDi\tGangi... | [
-0.0328340008854866,
-0.07071100175380707,
0.06049785390496254,
0.04192041978240013,
-0.06582847237586975,
-0.03820425271987915,
0.11941976100206375,
0.04916134476661682,
-0.08324074000120163,
0.03484851494431496,
0.05804090574383736,
-0.03657717630267143,
0.055817101150751114,
0.051896259... |
Di\tGangi\tet\tal,\t2012\n).\tIt\nis\tthought\tto\tbe\tcaused\tby\tthiamin\tdepletion\tand,\tbecause\tthere\tis\tlittle\tstorage\tin\tthe\tbody\t(\nFrank,\n2015\n),\ta\tdeficiency\tcan\tdevelop\tin\tas\tlittle\tas\t2\tweeks\tof\tvomiting\t(\nSelitsky\tet\tal,\t2006\n).\tThere\tis\tno\nconsensus\ton\tearly\tdiagnosis,\t... | [
-0.042988233268260956,
0.009532636031508446,
0.09938882291316986,
-0.07015633583068848,
-0.1284409910440445,
0.030542172491550446,
0.05780181288719177,
0.011875337921082973,
0.003408124903216958,
0.05359381437301636,
0.08903205394744873,
-0.023961881175637245,
0.037388235330581665,
0.04885... |
ophthalmoplegia,\tmental\tstatus\tchanges,\tand\tataxia\thas\tbeen\tfound\tin\tonly\t16%\tof\tknown\tHG\tcases.\nWomen\tin\t60%\tof\tcases\tdisplayed\tocular\tsymptoms,\t83%\thad\tcerebellar\tchanges,\tand\t52%\thad\nmemory\timpairment\t(\nDi\tGangi\tet\tal,\t2012\n).\tSymptoms\tare\toften\tvague\tand\tnonspecific,\tin... | [
0.013853268697857857,
-0.07373961061239243,
0.05224995315074921,
-0.001597123802639544,
-0.1426246166229248,
-0.018067199736833572,
0.10089894384145737,
0.03954491764307022,
-0.0392368845641613,
0.06718704849481583,
0.1052376851439476,
-0.06321689486503601,
0.01755322702229023,
0.041271001... |
).\tSymptoms\tare\toften\tvague\tand\tnonspecific,\tincluding\nheadaches,\n\tfatigue,\tabdominal\tdiscomfort,\tirritability,\tand\tinability\tto\tconcentrate.\tIf\tnot\ttreated\nquickly,\tWernicke’s\tencephalopathy\tcan\tprogress\tto\tKorsakoff\tsyndrome,\twith\tchronic\tmaternal\nmemory\timpairment\t(\nKloss\tet\tal,\... | [
-0.011064031161367893,
-0.04464128613471985,
0.03017267771065235,
-0.008844729512929916,
-0.09430358558893204,
0.0036227209493517876,
0.09216999262571335,
0.08348462730646133,
0.008527805097401142,
0.027951326221227646,
0.04412612318992615,
0.028627697378396988,
0.040856048464775085,
0.041... |
memory\timpairment\t(\nKloss\tet\tal,\t2018\n).\tThiamin\tblood\tlevels\tare\tnot\tuseful\tfor\tdiagnosis.\tInstead,\nthiamin\tis\tgiven\tintravenously,\tand\ta\tpresumptive\tdiagnosis\tis\tmade\tif\tthe\tpatient\tresponds.\tACOG\nrecommends\tgiving\n\t100\tmg\tIV\tthiamin\twith\tthe\tinitial\trehydration\tfluid,\tfoll... | [
0.0189387034624815,
0.019359374418854713,
0.036570288240909576,
-0.012420654296875,
-0.10118204355239868,
-0.02109660767018795,
0.06760015338659286,
0.06795048713684082,
0.023264868184924126,
-0.013436653651297092,
0.09722783416509628,
-0.007301060017198324,
0.04952187463641167,
-0.0019786... |
the\tnext\t2\tto\t3\tdays,\tfollowed\tby\tIV\tmultivitamins\t(\nACOG,\t2018b\n).\tCorrecting\tdeficiencies\tof\tniacin\nand\tmagnesium\talso\tmay\tbe\thelpful. | [
-0.013713575899600983,
-0.03609786182641983,
0.009262592531740665,
-0.024614503607153893,
-0.07439827919006348,
-0.00875177327543497,
0.04372269660234451,
0.017276642844080925,
-0.01047703716903925,
0.058292683213949203,
0.10984836518764496,
-0.024986224249005318,
0.014776844531297684,
0.0... |
In\tHG,\tearly\tenteral\ttube\tfeeding\tdoes\tnot\tconsistently\timprove\tbirthweight\t(\nGrooten\tet\tal,\t2017\n).\nWomen\twith\tsevere\temesis\tand\tretching\thave\toften\tdislodged\ttubes\tand\tare\tsometimes\n\treluctant\tfor\nreplacement.\tDuring\thospitalization,\tfrequent\tnursing\tchecks\ton\ttube\tplacement\t... | [
-0.01537188608199358,
-0.0730610266327858,
0.08225852251052856,
-0.013869617134332657,
-0.06014961376786232,
-0.02202681452035904,
0.07768933475017548,
0.03945368155837059,
-0.009641998447477818,
0.06247532367706299,
0.08472973108291626,
-0.006326702423393726,
0.03342939168214798,
0.047096... |
deprivation\tissues,\twhich\thave\tnot\tbeen\tfully\tappreciated\t(\nErick,\t2014\n).\tWhen\tenteral\tnutrition\tis\tnot\ntolerated\tand\toral\tintake\tis\tnot\tsufficient,\tparenteral\tnutrition\tshould\tbe\tconsidered\t(see\t\nChapter\n11\n).\tHistorically,\tproblems\twith\tinfections,\tas\twell\tas\thyperglycemia,\t... | [
0.014031504280865192,
-0.027403216809034348,
0.0689496099948883,
0.0231307540088892,
-0.07081428170204163,
0.030271826311945915,
0.05797019973397255,
0.08549215644598007,
-0.05843452364206314,
0.0646597221493721,
0.0638653114438057,
-0.015539034269750118,
0.04183747619390488,
0.04382670670... |
and\nrespiratory\tcompromise\thave\tall\tbeen\tseen\t(\nWorthington\tet\tal,\t2017\n).\tHowever,\twith\tcareful\nmanagement,\tincluding\tavoiding\toverfeeding,\tadequate\tglucose\tcontrol,\tand\tmeticulous\tvenous\naccess\tcare,\tthese\tproblems\tcan\tbe\tminimized\tor\teliminated.\tParenteral\tnutrition\thas\tsafely\t... | [
0.025561954826116562,
-0.030443275347352028,
0.06968657672405243,
-0.01750311441719532,
-0.1281660497188568,
-0.02064921334385872,
0.06436807662248611,
-0.012846068479120731,
-0.06211230903863907,
0.08685178309679031,
0.12396617978811264,
-0.03865557536482811,
0.011883977800607681,
0.03652... |
employed\tduring\tpregnancy\tfor\tHG,\tas\twell\tas\tGI\tdisorders\tsuch\tas\tshort\tbowel\tsyndrome\tand\nCrohn’s\tdisease\t(\nMogensen\tand\tErick,\t2017\n).\nWomen\thistorically\thave\tbeen\treassured\tthat\teven\twith\tHG\tthe\tfetus\tis\tprotected,\tusing\tadequate\nbirth\tweight\tas\tevidence.\tHowever,\tgiven\tt... | [
0.000552587618585676,
0.042850349098443985,
0.04892393946647644,
-0.0031221022363752127,
-0.05168198421597481,
0.07181212306022644,
0.07995853573083878,
-0.00916082039475441,
-0.030658330768346786,
0.07706525176763535,
0.08649767190217972,
-0.010965708643198013,
0.005027970299124718,
-0.01... |
birth\tweight\tdoes\tnot\tnecessarily\tpredict\tlong-term\thealth\tand\tthat\tthere\tare\tconsequences\tof\tearly\nmalnutrition,\teven\tif\tlater\tresolved\t(\nErick,\t2014\n;\t\nRoseboom\tet\tal,\t2011\n).\tHG\tmerits\tearly\tand\naggressive\n\tattention\tand\ttreatment.\nSome\twomen\tdevelop\t\nptyalism\tgravidarum\n... | [
0.0010679765837267041,
0.03755050525069237,
0.07360413670539856,
0.017393164336681366,
-0.07378226518630981,
0.029586194083094597,
0.04022989794611931,
-0.032956238836050034,
-0.07119254767894745,
0.08453478664159775,
0.11960697919130325,
-0.033077504485845566,
0.010406572371721268,
-0.033... |
,\tor\texcess\tsaliva.\tIt\toften\thas\tan\tabrupt\tonset\t2\tto\t3\nweeks\tafter\tconception\tand\treported\tprevalence\tvaries\twidely,\tfrom\t0.08%\tin\tthe\tUnited\tStates\tto\n35%\tin\tTurkey\t(\nThaxter\tNesbeth\tet\tal,\t2016\n).\tHormonal\tchanges\tare\tthought\tto\tplay\ta\trole\tbut\ta\tnew\npossible\tcausal\... | [
-0.005122671369463205,
-0.06459269672632217,
0.05325769633054733,
-0.04868750646710396,
-0.08225616812705994,
0.013805811293423176,
0.08141601085662842,
0.007417516317218542,
0.019048580899834633,
0.052598778158426285,
0.10848855972290039,
-0.024782631546258926,
0.052945856004953384,
0.023... |
Lowry\tand\tWoods,\t2018\n).\nSalivary\toutput\tcan\tbe\tsubstantial,\tup\tto\t1.5\tto\t2.0\t1iters/day,\tand\tcan\tbe\ta\tsource\tof\tlost\telectrolytes\nas\twell\tas\tdehydration\t(\nThaxter\tNesbeth\tet\tal,\t2016\n)\tbecause\tthe\tsaliva\tis\toften\tspit\tinto\ta\tcup\tor\npaper\ttissue.\tIt\tmay\tinterfere\twith\t... | [
-0.007866515778005123,
-0.02215414121747017,
-0.005281694233417511,
-0.06879756599664688,
-0.08555962145328522,
-0.004382043611258268,
0.08373420685529709,
-0.06422436982393265,
-0.004037751816213131,
0.026433201506733894,
0.07917442172765732,
-0.021122271195054054,
0.03806466981768608,
-0... |
salivary\tglands.\tBecause\tthe\tsaliva\tis\texcessively\tthick\tand\tthe\ttongue\tis\toften\tenlarged\tand\tcoated,\nptyalism\toften\tinterferes\twith\tspeech.\tIt\tmay\tincrease\tthe\tnausea\tand\tvomiting\tand\toften\tadversely\naffects\tthe\tsense\tof\ttaste.\tIt\tinterferes\twith\tsleep\tand\tis\tassociated\twith\... | [
0.026210317388176918,
-0.08623287826776505,
0.10015617311000824,
-0.02773744985461235,
-0.09132439643144608,
0.005729704163968563,
0.13892389833927155,
-0.043394602835178375,
0.0013571901945397258,
0.0640704333782196,
0.07950415462255478,
-0.06206931918859482,
0.004743361379951239,
0.03876... |
However,\tptyalism\tdoes\tnot\tappear\tdangerous\tfor\tthe\tfetus.\tAntihistamines\tmay\tbe\thelpful,\tas\tmay\nchewing\tgum\tor\tsucking\ton\thard\tcandy,\tthroat\tlozenges,\tlemon\tdrops,\tor\tice.\tPtyalism\tceases\tat\ndelivery\n\tbut\tmay\tend\tafter\tthe\tfirst\ttrimester\tfor\tsome\tpeople\t(\nThaxter\tNesbeth\t... | [
-0.004576869774609804,
-0.045083239674568176,
0.06733804941177368,
-0.054818905889987946,
-0.09665758907794952,
0.005122204776853323,
0.042060401290655136,
-0.041852254420518875,
-0.0004235720552969724,
0.09175766259431839,
0.13632456958293915,
-0.017489740625023842,
0.0379047766327858,
0.... |
Thaxter\tNesbeth\tet\tal,\t2016\n).\nOral\thealth\nGood\toral\thealth\tis\timportant\tthroughout\tone’s\tlifetime,\tincluding\tduring\tpregnancy\t(see\t\nChapter\n24\n).\tPregnant\twomen\tcan\treceive\tdental\tcare\twhile\tpregnant,\twith\tsome\tqualifications.\tThe\tNational\nMaternal\tand\tChild\tOral\tHealth\tResour... | [
-0.010270497761666775,
-0.02832162380218506,
0.05307149142026901,
-0.027446866035461426,
-0.12482301145792007,
0.045242998749017715,
0.05994604900479317,
0.016777141019701958,
0.01464847382158041,
0.07607704401016235,
0.13742175698280334,
-0.015094536356627941,
0.027386978268623352,
-0.036... |
is\n\tassociated\twith\tpreterm\tbirth\tand\tLBW,\ttreatment\tdoes\tnot\tappear\tto\tlower\tthat\trisk.\tHowever,\noptimal\tmaternal\toral\thygiene\tmay\tlower\tthe\tamount\tof\t\nStreptococcus\tmutans\n\ttransmitted\tto\tthe\ninfant\tthrough\tsharing\tspoons\tor\tlicking\tpacifiers,\tthus\tlowering\tor\tdelaying\tthe\... | [
0.029170382767915726,
-0.06245109438896179,
0.04884697496891022,
-0.05500141531229019,
-0.10937239974737167,
0.0084536736831069,
0.04508032649755478,
-0.02463475614786148,
-0.010037635453045368,
0.09490379691123962,
0.13349299132823944,
-0.038175757974386215,
0.057516902685165405,
0.040570... |
caries.\nDuring\tpregnancy,\tincreased\tinflammatory\tresponse\tto\tdental\tplaque\tcauses\tgingivae\tto\tswell\tand\nbleed\n\tmore\teasily.\tRinsing\twith\tsalt\twater\t(1\ttsp\tsalt\tin\t1\tcup\twarm\twater)\tcan\thelp\tsoothe\tthe\nirritation.\tErosion\tof\tenamel\tmay\toccur\twith\tincreased\texposure\tto\tgastric\... | [
-0.028916021808981895,
-0.07739453762769699,
0.09041228890419006,
-0.007193537428975105,
-0.13279107213020325,
-0.015874965116381645,
0.0863797664642334,
-0.00029439778882078826,
-0.019112158566713333,
0.0436263270676136,
0.07443264126777649,
-0.042601361870765686,
0.04331488162279129,
0.0... |
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