OTAR3088/BioData-CellLine_annotated · Data Studio

PMCID string	Sentences string	ner list
PMC11706297	After checking with TLC, the mixture was poured into crushed ice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "checking", "with", "TLC", ",", "the", "mixture", "was", "poured", ...
PMC10033453	VMG induced oncolysis in all sarcoma cell lines at high MOIs (10 and 1), with variable cytotoxic effects at lower MOIs (0.1 and 0.01) in vitro as shown by MTS and crystal violet assays.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Methods: In this study 18 children with MDS are included.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Methods", ":", "In", "this", "study", "18", "children", "with", "MDS", "are", "...
PMC9592219	Small-molecule active ingredients with high scores were selected.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Small-molecule", "active", "ingredients", "with", "high", "scores", "were", "selected", "." ] } ]
PMC9429973	A. Da Ros, V. Indio, E. Porcù, G. Borella, M. Benetton, C. Tregnago, G. Longo, S. Cairo, B. Michielotto, S. Bresolin, B. Buldini, A. Pession, F. Locatelli, M. Pigazzi Department of Women’s and Children’s Health, Haematology-Oncology Clinic and Laboratory, University of Padova, Padova; Department of veterinary medical s...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6364197	So we used 80 µg/ml CTCPS for drug testing applications.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "So", "we", "used", "80", "µg/ml", "CTCPS", "for", "drug", "testing", "applications", "." ...
PMC10957991	A1 upright microscope equipped with Zeiss Axiocam 506 color camera, Zeiss HXP 200C Fluorescence Illuminator, 100 W halogen illumination and Specimen holder for 76 × 26 mm sliders.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Among them, 27 (8.3%) were found to be positive for CD5, out of which 10 pts were designated at the pathology report as CD5 +/- (5 pts) or CD5 -/+ (5 pts), while the rest 17 pts were clearly CD5+.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7334607	On the other hand, all replicates demonstrate possible collateral sensitivity to SP over time, although these results are not conclusive as the control evolutionary replicates moved toward resistance more than the experimental evolutionary replicates moved toward sensitivity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	2.	[ { "tags": [ "O", "O" ], "tokens": [ "2", "." ] } ]
PMC7215832	In CCRF-CEM cells, treatment with RX-3117, DAC or AzaC at their IC50 concentrations did not affect MTX uptake at pH 7.4 (Figure 3A).	[ { "tags": [ "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11661040	Flow cytometry showed that wnt signaling pathway inhibitors partially blocked the transition from G1/G0 to S phase of osteosarcoma cells compared with the blank control group.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11434983	Although EGFR TKIs are the treatment of choice, especially for NSCLC, relapse and drug resistance are observed in many patients after treatment .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC9429973	We thus believe that a screening of patients at risk to develop AL amyloidosis could lead to an early diagnosis and better prognosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "We", ...
PMC7823217	This is likely due to tumor heterogeneity, the presence of cancer stem cells and cancer cell plasticity , indicating the need for a combination of multiple drug treatments including targeted therapies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC6934009	Fluorescence microscope (Olympus Corporation) was used for detection of morphological changes in the cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fluorescence", "microscope", "(", "Olympus", "Corporation", ...
PMC11190538	Following aspiration of the cell growth medium, 50 μl of the C-phycocyanin was diluted in the medium (the same concentrations used in the cytotoxicity assay) and a constant multiplicity of infection (MOI) of the HCoV-229E in 50 μl of the appropriate medium was added to the wells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10729469	These cells would then generate neuroprotective anti-inflammatory outcomes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "These", "cells", "would", "then", "generate", "neuroprotective", "anti-inflammatory", "outcomes", "." ] } ]
PMC11746948	This analysis revealed 37 proteins interacting with GPX4 in both cell lines (Fig. 5a).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "analysis", "revealed", "37", "proteins", "inte...
PMC10538569	Gating strategy for analysis of DC : TC cocultures.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gating", "strategy", "for", "analysis", "of", "DC", ":", "TC", "cocultures", "." ] } ]
PMC11487720	Whether pY287-WWOX is subjected to ubiquitination and proteasomal degradation remains to be established.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Whether", "pY287-WWOX", "is", "subjected", "to", "ubiquitination", "and", "...
PMC11543885	Note: Avoid multiple freeze-thaw cycles.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Note", ":", "Avoid", "multiple", "freeze-thaw", "cycles", "." ] } ]
PMC3765139	To isolate overall differences, appropriate differences were considered significant at p ≤ 0.001.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "isolate", "overall", "differences", ",", "appropriate", "differe...
PMC11720808	The stable TLR4-overexpressing 143B cells and wild-type 143B cells were treated with DMSO or SCU.	[ { "tags": [ "O", "O", "O", "B-CellLine", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "stable", "TLR4-overexpressing", "143B", "cells...
PMC9429973	Using Cox regression analysis, it was found that in patients with p16+/p53+, the risk of developing an adverse event was 13.6 times higher than in the group of subjects with p16-/p53- (HR=13.6; 95% CI=10.2 -37.7).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11658074	UVB radiation promotes the generation and accumulation of reactive oxygen species (ROS) and induces DNA damage [7–9].	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "UVB", "radiation", ...
PMC11680562	The experimental results were analyzed and represented by the mean value of the standard deviation using Graph Pad PRISM, USA, the experiments are conducted thrice.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC10213179	Fifty micrograms of total cell extract (input) was loaded as reference.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Fifty", "micrograms", "of", "total", "cell", "extract", "(", "input", ...
PMC9429973	Lung was the main infection site in 53 cases, followed by 6 cases of urinary system infection, 3 cases of skin infection, 2 cases of perianal infection, and 45 cases with no clear infection foci.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC8973085	The antiproliferative properties of the compounds were assessed using the 3-[4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) test against HepG-2, HCT-116, MCF-7, and BJ-1 cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC6268318	= chloroformic and methanolic extract; MeOH/MeCl2 ext.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "=", "chloroformic", "and", "methanolic", "extract", ";", "MeOH/MeCl2", "ext", "." ] } ]
PMC11381192	Upregulation of UBE2T expression is considered as a possible driver of MM initiation and aggressiveness.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Upregulation", "of", "UBE2", "T", "expression", "is", ...
PMC9895440	Interestingly, one attempt to impose an exhaustion state in human T cells utilized repetitive stimulation ex vivo with peptide-loaded human dendritic cells, which resulted in a reduction in cytokine secretion, but not degranulation or killing capacity.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11730000	Briefly, total protein from CHO-K1 cells was extracted using radioimmunoprecipitation lysis buffer (SantaCruz, Texas, USA) with phenylmethylsulphonylfluoride, protease inhibitor cocktail, and sodium orthovanadate.	[ { "tags": [ "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9960565	Similar results were obtained for the remaining prepared metallodendrimers (Figure S33–S41).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Similar", "results", "were", "obtained", "for", "the", "remaining", "prepar...
PMC10812665	Moreover, glucose may be converted to fructose/sorbitol or myo-inositol (Figure 11).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Moreover", ",", "glucose", "may", "be", "converted", "to", "fruc...
PMC11206251	It is noteworthy that caspase-9 and caspase-3 showed extremely significant differences when the concentration was at 50 μg·mL. We strongly believe that the development of strategies aimed at enhancing cell death will open the prospect of improving the success of cancer treatment by combining these natural TCM therapies...	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11129910	DNA was isolated from microdissection-enriched FFPE tissue.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "DNA", "was", "isolated", "from", "microdissection-enriched", "FFPE", "tissue", "." ] } ]
PMC10048572	Creso et al. demonstrated in a mouse model that the transplantation of cancer cells at doses of clonal cells to multiple recipients allows separation and investigation of subclones.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11590005	A growing body of evidence has revealed the pres-ence of modern racism in dental schools worldwide.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "growing", "body", "of", "evidence", "has", ...
PMC9429973	Aims: To evaluate the impact of Pola-R-CHP vs R-CHOP on PN using clinician- and patient-reported outcomes (ClinRO and PRO) data.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Aims", ...
PMC9844987	This study provides fundamental insights into transcriptional regulation, indicating shared mechanisms that can buffer stochastic, environmental, and genetic variation and how these affect the responsiveness and cell-type restricted activity of genes.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11599565	Moreover, the transition from an epithelial to a neuronal-like steady state was confirmed by the loss of EpCAM (epithelial), the gain of βIII-tubulin (neuronal) and Vimentin (see Figures SF10-13).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC7039683	Unexpectedly these elements were not consistently active in reporter assays carried out in zebrafish and mouse embryos.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unexpectedly", "these", "elements", "were", "not"...
PMC9429973	Implementation of this PET/TC guided strategy, regardless of stage at diagnosis, resulted in reduced exposure to chemotherapy and radiotherapy, contributing to the absence of severe treatment-related morbidity and mortality.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11348300	PpIX fluorescence image overlayed on background grayscale image depicting PpIX distribution in the organs of a nude mouse after i.v.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PpIX", "fluorescence", "imag...
PMC9776316	After the formation of the complex, JNK phosphorylated the cJUN to promote its activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "After", "the", "formation", "of", "the", "complex", ",", ...
PMC9780037	The detection of increased cyt c levels in the serum is correlated with a favorable prognosis.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "detection", "of", "increased", "cyt", "c", ...
PMC8711270	rAAVs can also be produced with the use of helper viruses (Clark, 2002).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "rAAVs", "can", "also", "be", "produced", "with", ...
PMC7504302	Remarkably, the expression ratio between the Claudin family gene CLDN15, which is normally downregulated in cells undergoing EMT, and the VIM gene, a marker for the mesenchymal state, was a significant discriminating signature between subgroups .	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC4816271	Overlaid T-cells cultured in 20nM CID are shown in red.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Overlaid", "T-cells", "cultured", "in", "20nM", "CID", "are", "shown", "in", "red", "." ...
PMC11612794	To evaluate the importance of this interaction surface in chicken DT40 cells, we replaced R192 and R193 with alanine in CENP-T (CENP-T) and introduced a mutant construct into the CENP-T locus in CENP-C cells expressing AID-CENP-T (CENP-C/CENP-T cells; Figure S4C).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11474209	Cellular processes are adversely affected by a series of events brought on by MCs' hyperphosphorylation of PP2A.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cellular", "processes", "are", "adversely", ...
PMC11802929	Underlined PG-TCR groups are those from panel (c).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Underlined", "PG-TCR", "groups", "are", "those", "from", "panel", "(", "c", ")", "." ]...
PMC11380329	The network is represented as a pie chart, where nodes correspond to parent masses of the metabolites.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "network", "is", "represented", ...
PMC11787651	This work describes the development of a high-throughput LC–MS platform for quantifying the complex histone PTMs.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "This", "work", "describes", "the", "de...
PMC11629143	At least 10,000 events were collected per sample.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "At", "least", "10,000", "events", "were", "collected", "per", "sample", "." ] } ]
PMC11711871	Upon HSD, both GR rat models presented an increase in the adrenal sEH protein abundance that was associated with an increase in hydrolyzed inactive forms of circulating omega-3 and omega-6 fatty acids and which was exacerbated in the GR rats.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11544122	Cells were lifted with dissociation solution Accutase (ThermoFischer Scientific cat.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Cells", "were", "lifted", "with", "dissociation", "solution", "Accutase", "(", "ThermoFisch...
PMC11802929	For bar plots, data are presented as mean values +/- SEM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "For", "bar", "plots", ",", "data", "are", "presented", "as", "mean", ...
PMC10589262	A, B Immunocytochemistry (ICC) analysis of KIT expression in gastrointestinal stromal tumor (GIST) (GIST430 and GIST882) and colon cancer (CC) cells (DLD-1 and Colo320DM) with or without permeabilization using triton X-100.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "B-CellLine", "O", "O", "O", "...
PMC11451940	Anal.	[ { "tags": [ "O", "O" ], "tokens": [ "Anal", "." ] } ]
PMC11206251	Hoechst33342 staining was used to observe the morphology of apoptosis after the HepG2 cells were treated with the PEIM.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Hoechst33342", "staining", "wa...
PMC11224020	h, Left, images of DCs transduced with NLS–GFP.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "h", ",", "Left", ",", "images", "of", "DCs", "transduced", "with", "NLS", ...
PMC11612315	Summary analysis of the inward currents reduced by BCTC alone (mean ± S.E.M.).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Summary", "analysis", "of", "the", "inward", "currents", "r...
PMC9429973	Results: A 56 year-old woman, previously treated for choriocarcinoma, presented to our Institution because of leukocytosis, anemia and diffuse cutaneous lesions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC9080589	The expression of PCDH8 was dramatically increased in TPC-1 (Fig. 2A) and BCPAP cells (Fig. 2B) after transfection, respectively, suggesting that the transfection was successful.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "...
PMC11680049	Following this, in a laminar flow hood, the cuttings were sterilized with a 0.1% solution of mercuric chloride (HgCl2) for 18 min and washed three times with sterile distilled water.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11468365	To enhance drug combinations further, additional factors beyond synergy and sensitivity scores should be considered to make informed decisions.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "To", "enhance", "drug", ...
PMC7642379	GO enrichment analysis of genes with high or moderate impact SNPs was performed using PANTHER classification system.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "GO", "enrichment", "analysis", "of", "genes", ...
PMC10919056	Analysis of the difference in TMB between high-RS and low-RS groups. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Analysis", "of", "the", "difference", "in", "TMB", "between", "high-RS", "and", ...
PMC8839885	The mechanisms that underlie OC platinum chemoresistance are largely unknown.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "mechanisms", "that", "underlie", "OC", "platinum", "chemoresistance", "are", "largely", "...
PMC11774251	Gene Ontology (GO) analysis (The red box represents the signaling pathways related to psoriasis influenced by Tan-I). (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Gene", "Onto...
PMC8270637	The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "raw", "data", "...
PMC11095939	not significant; ****p<0.0001 by two-way ANOVA.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "not", "significant", ";", "", "", "", "", "p<0.0001", "by", "two-way", "ANO...
PMC11476837	The analysis was performed in two biological replicates in two independent experiments.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "analysis", "was", "performed", "in", "two", "biological", "replicates", "...
PMC11363012	3% of all cells that were sampled).	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "3", "%", "of", "all", "cells", "that", "were", "sampled", ")", "." ] } ]
PMC11224020	Pathways and networks were considered significant with a false discovery rate of ≤0.05.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Pathways", "and", "networks", "were", "considered", "significant", "with", ...
PMC11377827	USP43 loss also did not alter HIF-1α binding to the VEGF HRE, similar to the lack of effect of USP43 depletion on VEGF using RNA-seq.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ...
PMC11518702	Observed increases in Syk phosphorylation, B-cell proliferation ex vivo, and RhoA activity each further indicated escalated BCR activation.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Observed", "increases", "in"...
PMC11515150	CD5 CAR-NK cells and nontransduced NK (NT-NK) cells were performed with target cells and at various ratios overnight.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "CD5", "CAR-NK", "cells", ...
PMC9895440	i Geometric mean CD25 upregulation relative to unstimulated cells for Teff co-cultured with T2 wt or T2 CD80 CD86 KO (T2 KO) cells.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC10734950	Given the data, there was a reduction in the JAK and STAT pathways suggesting the compound may be inhibiting an essential biological pathway responsible for tumor progression.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11766350	The main difference is that miRNAs can regulate multiple genes, while siRNAs have a single specific target.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "main", "difference", "is", "tha...
PMC9429973	Oxygen saturations were maintained normal without any changes in respiratory parameters.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Oxygen", "saturations", "were", "maintained", "normal", "without", "any", "changes", "in", ...
PMC8409415	Several studies have demonstrated that there is no cross‐resistance between platinum drugs and antimicrotubule agents.,	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Several", "studies", "have", "demonstrated", "that", "...
PMC11775197	Interestingly, a study demonstrated that increased bile acids lead to impaired Lgr5 intestinal stem cell (ISC) function by inhibiting PPARα-mediated FAO.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ ...
PMC11787381	Briefly, COS7 cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM), 10% decomplemented fetal bovine serum, and antibiotics, at 37 °C under 5% CO2.	[ { "tags": [ "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11718817	Tregs conditioned DCs to reduce their costimulatory activity, resulting in augmented coexpression of PD-1 and TIM-3 by CTLs, suggesting enhanced T cell exhaustion.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tok...
PMC11545737	Other virulence factors, such as those of Neisseria meningitidis, Neisseria gonorrhoeae, Salmonella enterica, and Helicobacter pylori affect pyroptosis pathways indirectly with important differences between pathogenic and commensal species of the same family.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11723947	S4f-r).	[ { "tags": [ "O", "O", "O" ], "tokens": [ "S4f-r", ")", "." ] } ]
PMC11025866	EBV causes infectious mononucleosis when infection occurs in adolescence or adulthood.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "EBV", "causes", "infectious", "mononucleosis", "when", "infection", "occurs", "in", "adoles...
PMC11173119	In addition, the ability of iPSCs to proliferate indefinitely and differentiate into various cells opens multiple avenues for studying FMF pathogenesis, screening drug candidates, and developing gene-based therapies.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9429973	Exploratory endpoints included duration of response of SVR35 and overall survival.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Exploratory", "endpoints", "included", "duration", "of", "response", "of", "SVR35", "and", ...
PMC11743316	The hypoxia-response pathway represents one of the most well-known pathways that has been demonstrated as being responsive to mROS.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "hypoxia-response", "pathway", ...
PMC9429973	Furthermore, treatment of ATO resistant NB4 cells (by gradual exposure to ATO or by expression of the PML A216V) revealed sensitivity of those cells to the combination VEN+S64315.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "B-CellLine", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC11657695	Boxes represent the interquartile range, upper and lower whiskers the largest and smallest values respectively.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Boxes", "represent", "the", "interquartile", "range", ...
PMC11727062	Furthermore, kaempferol exerts antiproliferative effects on melanoma cells by inhibiting the glycolytic pathway, a mechanism that correlates with the modulation of metabolic pathways and represents a therapeutic target in contemporary oncology.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...
PMC9844987	Absolute log2 fold change of differentially expressed promoters, split by variability quartiles, after 6 h of TNFα treatment. (	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Absolute", "log2", ...
PMC11075223	Until the Ming and Qing Dynasties, the related processing methods of Cimicifugae Rhizoma were more enriched, including stir-frying with honey, stir-baked to yellow, vinegar-processed, wine-processed, salt-processed and ginger juice processed.	[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", ...

PMC11706297

After checking with TLC, the mixture was poured into crushed ice.

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PMC10033453

VMG induced oncolysis in all sarcoma cell lines at high MOIs (10 and 1), with variable cytotoxic effects at lower MOIs (0.1 and 0.01) in vitro as shown by MTS and crystal violet assays.

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PMC9429973

Methods: In this study 18 children with MDS are included.

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PMC9592219

Small-molecule active ingredients with high scores were selected.

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PMC9429973

A. Da Ros, V. Indio, E. Porcù, G. Borella, M. Benetton, C. Tregnago, G. Longo, S. Cairo, B. Michielotto, S. Bresolin, B. Buldini, A. Pession, F. Locatelli, M. Pigazzi Department of Women’s and Children’s Health, Haematology-Oncology Clinic and Laboratory, University of Padova, Padova; Department of veterinary medical s...

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PMC6364197

So we used 80 µg/ml CTCPS for drug testing applications.

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PMC10957991

A1 upright microscope equipped with Zeiss Axiocam 506 color camera, Zeiss HXP 200C Fluorescence Illuminator, 100 W halogen illumination and Specimen holder for 76 × 26 mm sliders.

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PMC9429973

Among them, 27 (8.3%) were found to be positive for CD5, out of which 10 pts were designated at the pathology report as CD5 +/- (5 pts) or CD5 -/+ (5 pts), while the rest 17 pts were clearly CD5+.

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PMC7334607

On the other hand, all replicates demonstrate possible collateral sensitivity to SP over time, although these results are not conclusive as the control evolutionary replicates moved toward resistance more than the experimental evolutionary replicates moved toward sensitivity.

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PMC9429973

2.

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PMC7215832

In CCRF-CEM cells, treatment with RX-3117, DAC or AzaC at their IC50 concentrations did not affect MTX uptake at pH 7.4 (Figure 3A).

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PMC11661040

Flow cytometry showed that wnt signaling pathway inhibitors partially blocked the transition from G1/G0 to S phase of osteosarcoma cells compared with the blank control group.

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PMC11434983

Although EGFR TKIs are the treatment of choice, especially for NSCLC, relapse and drug resistance are observed in many patients after treatment .

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PMC9429973

We thus believe that a screening of patients at risk to develop AL amyloidosis could lead to an early diagnosis and better prognosis.

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PMC7823217

This is likely due to tumor heterogeneity, the presence of cancer stem cells and cancer cell plasticity , indicating the need for a combination of multiple drug treatments including targeted therapies.

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PMC6934009

Fluorescence microscope (Olympus Corporation) was used for detection of morphological changes in the cells.

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PMC11190538

Following aspiration of the cell growth medium, 50 μl of the C-phycocyanin was diluted in the medium (the same concentrations used in the cytotoxicity assay) and a constant multiplicity of infection (MOI) of the HCoV-229E in 50 μl of the appropriate medium was added to the wells.

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PMC10729469

These cells would then generate neuroprotective anti-inflammatory outcomes.

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PMC11746948

This analysis revealed 37 proteins interacting with GPX4 in both cell lines (Fig. 5a).

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PMC10538569

Gating strategy for analysis of DC : TC cocultures.

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PMC11487720

Whether pY287-WWOX is subjected to ubiquitination and proteasomal degradation remains to be established.

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PMC11543885

Note: Avoid multiple freeze-thaw cycles.

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PMC3765139

To isolate overall differences, appropriate differences were considered significant at p ≤ 0.001.

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PMC11720808

The stable TLR4-overexpressing 143B cells and wild-type 143B cells were treated with DMSO or SCU.

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PMC9429973

Using Cox regression analysis, it was found that in patients with p16+/p53+, the risk of developing an adverse event was 13.6 times higher than in the group of subjects with p16-/p53- (HR=13.6; 95% CI=10.2 -37.7).

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PMC11658074

UVB radiation promotes the generation and accumulation of reactive oxygen species (ROS) and induces DNA damage [7–9].

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PMC11680562

The experimental results were analyzed and represented by the mean value of the standard deviation using Graph Pad PRISM, USA, the experiments are conducted thrice.

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PMC10213179

Fifty micrograms of total cell extract (input) was loaded as reference.

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PMC9429973

Lung was the main infection site in 53 cases, followed by 6 cases of urinary system infection, 3 cases of skin infection, 2 cases of perianal infection, and 45 cases with no clear infection foci.

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PMC8973085

The antiproliferative properties of the compounds were assessed using the 3-[4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) test against HepG-2, HCT-116, MCF-7, and BJ-1 cells.

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PMC6268318

= chloroformic and methanolic extract; MeOH/MeCl2 ext.

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PMC11381192

Upregulation of UBE2T expression is considered as a possible driver of MM initiation and aggressiveness.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Upregulation", "of", "UBE2", "T", "expression", "is", ...

PMC9895440

Interestingly, one attempt to impose an exhaustion state in human T cells utilized repetitive stimulation ex vivo with peptide-loaded human dendritic cells, which resulted in a reduction in cytokine secretion, but not degranulation or killing capacity.

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PMC11730000

Briefly, total protein from CHO-K1 cells was extracted using radioimmunoprecipitation lysis buffer (SantaCruz, Texas, USA) with phenylmethylsulphonylfluoride, protease inhibitor cocktail, and sodium orthovanadate.

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PMC9960565

Similar results were obtained for the remaining prepared metallodendrimers (Figure S33–S41).

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PMC10812665

Moreover, glucose may be converted to fructose/sorbitol or myo-inositol (Figure 11).

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PMC11206251

It is noteworthy that caspase-9 and caspase-3 showed extremely significant differences when the concentration was at 50 μg·mL. We strongly believe that the development of strategies aimed at enhancing cell death will open the prospect of improving the success of cancer treatment by combining these natural TCM therapies...

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PMC11129910

DNA was isolated from microdissection-enriched FFPE tissue.

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PMC10048572

Creso et al. demonstrated in a mouse model that the transplantation of cancer cells at doses of clonal cells to multiple recipients allows separation and investigation of subclones.

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PMC11590005

A growing body of evidence has revealed the pres-ence of modern racism in dental schools worldwide.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "A", "growing", "body", "of", "evidence", "has", ...

PMC9429973

Aims: To evaluate the impact of Pola-R-CHP vs R-CHOP on PN using clinician- and patient-reported outcomes (ClinRO and PRO) data.

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PMC9844987

This study provides fundamental insights into transcriptional regulation, indicating shared mechanisms that can buffer stochastic, environmental, and genetic variation and how these affect the responsiveness and cell-type restricted activity of genes.

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PMC11599565

Moreover, the transition from an epithelial to a neuronal-like steady state was confirmed by the loss of EpCAM (epithelial), the gain of βIII-tubulin (neuronal) and Vimentin (see Figures SF10-13).

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PMC7039683

Unexpectedly these elements were not consistently active in reporter assays carried out in zebrafish and mouse embryos.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Unexpectedly", "these", "elements", "were", "not"...

PMC9429973

Implementation of this PET/TC guided strategy, regardless of stage at diagnosis, resulted in reduced exposure to chemotherapy and radiotherapy, contributing to the absence of severe treatment-related morbidity and mortality.

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PMC11348300

PpIX fluorescence image overlayed on background grayscale image depicting PpIX distribution in the organs of a nude mouse after i.v.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "PpIX", "fluorescence", "imag...

PMC9776316

After the formation of the complex, JNK phosphorylated the cJUN to promote its activation.

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PMC9780037

The detection of increased cyt c levels in the serum is correlated with a favorable prognosis.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "The", "detection", "of", "increased", "cyt", "c", ...

PMC8711270

rAAVs can also be produced with the use of helper viruses (Clark, 2002).

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PMC7504302

Remarkably, the expression ratio between the Claudin family gene CLDN15, which is normally downregulated in cells undergoing EMT, and the VIM gene, a marker for the mesenchymal state, was a significant discriminating signature between subgroups .

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PMC4816271

Overlaid T-cells cultured in 20nM CID are shown in red.

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PMC11612794

To evaluate the importance of this interaction surface in chicken DT40 cells, we replaced R192 and R193 with alanine in CENP-T (CENP-T) and introduced a mutant construct into the CENP-T locus in CENP-C cells expressing AID-CENP-T (CENP-C/CENP-T cells; Figure S4C).

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PMC11474209

Cellular processes are adversely affected by a series of events brought on by MCs' hyperphosphorylation of PP2A.

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PMC11802929

Underlined PG-TCR groups are those from panel (c).

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "Underlined", "PG-TCR", "groups", "are", "those", "from", "panel", "(", "c", ")", "." ]...

PMC11380329

The network is represented as a pie chart, where nodes correspond to parent masses of the metabolites.

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PMC11787651

This work describes the development of a high-throughput LC–MS platform for quantifying the complex histone PTMs.

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PMC11629143

At least 10,000 events were collected per sample.

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PMC11711871

Upon HSD, both GR rat models presented an increase in the adrenal sEH protein abundance that was associated with an increase in hydrolyzed inactive forms of circulating omega-3 and omega-6 fatty acids and which was exacerbated in the GR rats.

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PMC11544122

Cells were lifted with dissociation solution Accutase (ThermoFischer Scientific cat.

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PMC11802929

For bar plots, data are presented as mean values +/- SEM.

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PMC10589262

A, B Immunocytochemistry (ICC) analysis of KIT expression in gastrointestinal stromal tumor (GIST) (GIST430 and GIST882) and colon cancer (CC) cells (DLD-1 and Colo320DM) with or without permeabilization using triton X-100.

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PMC11451940

Anal.

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PMC11206251

Hoechst33342 staining was used to observe the morphology of apoptosis after the HepG2 cells were treated with the PEIM.

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PMC11224020

h, Left, images of DCs transduced with NLS–GFP.

[ { "tags": [ "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O", "O" ], "tokens": [ "h", ",", "Left", ",", "images", "of", "DCs", "transduced", "with", "NLS", ...

PMC11612315

Summary analysis of the inward currents reduced by BCTC alone (mean ± S.E.M.).

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PMC9429973

Results: A 56 year-old woman, previously treated for choriocarcinoma, presented to our Institution because of leukocytosis, anemia and diffuse cutaneous lesions.

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PMC9080589

The expression of PCDH8 was dramatically increased in TPC-1 (Fig. 2A) and BCPAP cells (Fig. 2B) after transfection, respectively, suggesting that the transfection was successful.

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PMC11680049

Following this, in a laminar flow hood, the cuttings were sterilized with a 0.1% solution of mercuric chloride (HgCl2) for 18 min and washed three times with sterile distilled water.

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PMC11468365

To enhance drug combinations further, additional factors beyond synergy and sensitivity scores should be considered to make informed decisions.

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PMC7642379

GO enrichment analysis of genes with high or moderate impact SNPs was performed using PANTHER classification system.

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PMC10919056

Analysis of the difference in TMB between high-RS and low-RS groups. (

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PMC8839885

The mechanisms that underlie OC platinum chemoresistance are largely unknown.

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PMC11774251

Gene Ontology (GO) analysis (The red box represents the signaling pathways related to psoriasis influenced by Tan-I). (

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PMC8270637

The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation.

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PMC11095939

not significant; ****p<0.0001 by two-way ANOVA.

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PMC11476837

The analysis was performed in two biological replicates in two independent experiments.

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PMC11363012

3% of all cells that were sampled).

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PMC11224020

Pathways and networks were considered significant with a false discovery rate of ≤0.05.

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PMC11377827

USP43 loss also did not alter HIF-1α binding to the VEGF HRE, similar to the lack of effect of USP43 depletion on VEGF using RNA-seq.

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PMC11518702

Observed increases in Syk phosphorylation, B-cell proliferation ex vivo, and RhoA activity each further indicated escalated BCR activation.

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PMC11515150

CD5 CAR-NK cells and nontransduced NK (NT-NK) cells were performed with target cells and at various ratios overnight.

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PMC9895440

i Geometric mean CD25 upregulation relative to unstimulated cells for Teff co-cultured with T2 wt or T2 CD80 CD86 KO (T2 KO) cells.

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PMC10734950

Given the data, there was a reduction in the JAK and STAT pathways suggesting the compound may be inhibiting an essential biological pathway responsible for tumor progression.

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PMC11766350

The main difference is that miRNAs can regulate multiple genes, while siRNAs have a single specific target.

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PMC9429973

Oxygen saturations were maintained normal without any changes in respiratory parameters.

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PMC8409415

Several studies have demonstrated that there is no cross‐resistance between platinum drugs and antimicrotubule agents.,

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PMC11775197

Interestingly, a study demonstrated that increased bile acids lead to impaired Lgr5 intestinal stem cell (ISC) function by inhibiting PPARα-mediated FAO.

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PMC11787381

Briefly, COS7 cells were cultured in Dulbecco’s modified Eagle’s medium (DMEM), 10% decomplemented fetal bovine serum, and antibiotics, at 37 °C under 5% CO2.

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PMC11718817

Tregs conditioned DCs to reduce their costimulatory activity, resulting in augmented coexpression of PD-1 and TIM-3 by CTLs, suggesting enhanced T cell exhaustion.

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PMC11545737

Other virulence factors, such as those of Neisseria meningitidis, Neisseria gonorrhoeae, Salmonella enterica, and Helicobacter pylori affect pyroptosis pathways indirectly with important differences between pathogenic and commensal species of the same family.

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PMC11723947

S4f-r).

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PMC11025866

EBV causes infectious mononucleosis when infection occurs in adolescence or adulthood.

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PMC11173119

In addition, the ability of iPSCs to proliferate indefinitely and differentiate into various cells opens multiple avenues for studying FMF pathogenesis, screening drug candidates, and developing gene-based therapies.

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PMC9429973

Exploratory endpoints included duration of response of SVR35 and overall survival.

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PMC11743316

The hypoxia-response pathway represents one of the most well-known pathways that has been demonstrated as being responsive to mROS.

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PMC9429973

Furthermore, treatment of ATO resistant NB4 cells (by gradual exposure to ATO or by expression of the PML A216V) revealed sensitivity of those cells to the combination VEN+S64315.

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PMC11657695

Boxes represent the interquartile range, upper and lower whiskers the largest and smallest values respectively.

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PMC11727062

Furthermore, kaempferol exerts antiproliferative effects on melanoma cells by inhibiting the glycolytic pathway, a mechanism that correlates with the modulation of metabolic pathways and represents a therapeutic target in contemporary oncology.

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PMC9844987

Absolute log2 fold change of differentially expressed promoters, split by variability quartiles, after 6 h of TNFα treatment. (

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PMC11075223

Until the Ming and Qing Dynasties, the related processing methods of Cimicifugae Rhizoma were more enriched, including stir-frying with honey, stir-baked to yellow, vinegar-processed, wine-processed, salt-processed and ginger juice processed.

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