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American visceral leishmaniasis (avl) is a serious public health problem in brazil and presents a new epidemiological profile associated with domestic environments and, in this context, lutzomyia (lutzomyia) longipalpis is important considering its capacity to adapt to a wide range of impacted habitats, in addition to ... |
A curative therapy has not been established for pd, and a combination of drug therapy, surgical treatment, and physical therapy is recognized as the standard treatment1, 2 . The estimated incidence of pd in japan is 50 per 100,000 in the overall population and 200 per 100,000 in the population aged 64 or older3 . The n... |
Oral lichen planus (olp) is a chronic inflammatory disease affecting 1 - 2% of general adult population . Andreasen s classical classification was modified by other authors who sub classified olp to reticular, atrophic, and erosive forms . In the erosive form one theory is that in olp, autocytotoxic cd t - cells initia... |
Posttraumatic stress disorder (ptsd) is an anxiety disorder that can develop following exposure to traumatic life events . Central clinical features of ptsd include a persistent, heightened experience of alarm and distress, as well as a failure of extinction processes to diminish the emotional impact of traumatic memor... |
Wide disparities in health outcomes have been described for racial and ethnic minorities in the united states . The institute of medicine, charged with examining disparate health outcomes, found that a large body of research supports inequities in health care as possible contributors to inequities in health . Though di... |
Surveys on skin diseases of dogs demonstrate that neoplastic tumors of the skin are common [13]. Several studies report that in dogs the skin is the most commonly affected organ for both neoplastic and nonneoplastic tumors [47]. In one study, it has long been recognized among human populations that incidence rates and ... |
Each year 55,000 to 65,000 major lower extremity amputations are performed in the usa, making lower extremity amputation one of the most common vascular surgery procedures . Major lower extremity amputation, either below- or above - knee amputation, is associated with significant morbidity and mortality . Patients with... |
. Early detection of a supraspinatus tear using an accurate physical examination is essential to avoiding expensive and invasive additional tests . Unfortunately, only a few physical examinations that can detect isolated lesions of the supraspinatus alone are available in the clinical setting . The empty can (ec) test,... |
It usually presents at, or soon after birth with hyperkeratotic verrucous dark - brown ridges . Porcupine men and systematized epidermal naevus have also been used to describe these lesions . Based on the pattern of distribution, five clinical variants namely brocq type, lambert type, curth - macklin type, rheydt type ... |
(caesalpiniaceae) has great therapeutic implication in indian system of medicine and exerts an antipyretic, analgesic, antiinflammatory, and hypoglycemic effects [1, 2]. Over the past few years, there has been an exponential growth in study of pharmacological properties of this plant [35]. Antioxidant components are mi... |
Betathalassemia major is one of the commonest hereditary hemoglobinopathies, characterized by reduced or absent betaglobin chain synthesis 1 . Management is based on regular blood transfusions to suppress ineffective erythropoiesis, with the goal to maintain pretransfusion hemoglobin concentration above 90 g / l 2 . Re... |
Spontaneous central vein thrombosis is a rare but potentially serious condition as it can present with a fatal pulmonary embolism . Activated protein c resistance (apc - r) due to homozygous factor v leiden mutation is an exceptional cause of spontaneous central venous thrombosis . We describe here a right - sided inte... |
Sarcomatoid carcinomas of the lung are very uncommon tumors, comprising between 0.3 and 3% of all non - small lung carcinomas . It is a heterogeneous group of poorly differentiated carcinomas with two cell types: sarcomatoid or sarcomatous morphology with giant and/or spindle cells . Their clinical presentation is not ... |
Patients with schizophrenia have a two- to threefold higher risk of premature death than those without schizophrenia . This increased mortality is accounted for by a combination of factors, such as lifestyle factors, high suicide rates (especially in young male patients soon after diagnosis), premature development of c... |
Though the most common presentation of obstructive uropathy is urosepsis, this disorder may be associated with hyponatremia and loss of salt in the urine . The present case posed a diagnostic challenge because despite the presence of an obstructive salt losing uropathy, the urinary salt concentration was paradoxically ... |
Secondary brain stem injury is associated with transtentorial herniation, and manifests as duret hemorrhages . Such an injury has been considered a terminal brain stem event with a high morbidity and mortality, sometimes discouraging continuation of care . However, there have been rare instances where patients have had... |
Rhinitis sicca or generally speaking dry nose is a rather frequent problem involving many people . Many symptoms during dry nose could be encountered ranging from subjective sensation of the dry nose and itching up to mild burning, nasal obstruction, crusting associated with unpleasant smell, epistaxis, and diminished ... |
Breast cancer remains a significant public health challenge both in the united states and worldwide . While breast cancer is potentially curable when detected at an early stage, it remains incurable in the metastatic setting . Hence, there has been a major effort to detect breast cancer early, optimize the management o... |
World - wide, at least 2.8 million people die each year as a result of being overweight or obese and an estimated 35.8 million (2.3%) of global dalys are caused by overweight or obesity . Overweight and obesity lead to adverse metabolic effects on blood pressure, cholesterol, triglycerides (tg) and insulin resistance .... |
Gene fusion leading to the formation of multidomain proteins is one of the major routes of protein evolution . Gene fusions characteristically bring together proteins that function in a concerted manner, such as successive enzymes in metabolic pathways, enzymes and the domains involved in their regulation, or dna - bin... |
Influenza a virus (iav) is a common infectious pathogen in humans, which occasionally causes influenza - associated encephalopathy (iae). Iae is characterized by severe neurological complications, such as convulsive seizures, loss of consciousness, and abnormal behaviors.1,2 oseltamivir phosphate (op) is a selective ne... |
Due to their collective significance in mediating the host response against pathogens, the genes of the interferon response have been an area of particular focus in the field of antiviral defense . Understanding the biology of interferon - stimulated genes is challenging because of the diversity in their specificity an... |
The term haemorrhagic disease of the newborn (hdn) was coined by charles townsend in 1894 to describe an acquired bleeding disorder in the newborn due to vitamin k deficiency . Nowadays, the term hdn is replaced by vitamin k deficiency bleeding (vkdb), as neonatal bleeding is often not due to vitamin k deficiency and v... |
During the past decade, the patterns of diseases generated by shiga toxin - producing escherichia coli (stec) strains have changed from a clinical novelty to a global public health problem . This group of e. coli strains can cause a spectrum of human diseases, ranging from symptom - free carriage to severe bloody diarr... |
Solubility of a drug is an important property that mainly influences the extent of oral bioavailability . Enhancement of oral bioavailability of poorly water soluble drugs is the most challenging aspect of drug development . Most of the new chemical entities suffer from low bioavailability due to their low aqueous solu... |
Trauma is still one of the leading causes of death among people aged 45 and younger . The annual economic burden of direct and indirect costs in germany alone is estimated to be around 40 billion euros annually . Due to the heterogeneity of trauma, complex injury patterns, and broad variability of therapeutic options, ... |
Emergency medical services (ems) providers constantly deal with situations associated with high stress and anxiety (1). Given the serious nature of burn injuries, dealing with burn emergencies pre - hospital emergency teams and hospital staff face various problems, particularly in times of major burn emergencies, when ... |
All the chemicals used were of analytical grade and purified by standard methods prior to use . The melting points were measured using a stuart scientific melting point apparatus smp3 (uk) and are uncorrected . The nmr spectra were taken using bruker dpx 300 mhz instrument at organic chemistry institute, bonn, germany ... |
Lyme disease (ld) is an increasing health burden on the australian community requiring wider diagnostic recognition.1 borrelia burgdorferi sensu lato (bbsl) are closely related spirochetal species that are the causative agents of ld in humans.2 the author has previously reported the endemic presence of ld in australia ... |
Tinnitus, defined as the perception of sound that results exclusively from activity within the nervous system without any corresponding mechanical, vibratory activity within the cochlea, and not related to external stimulation of any kind it is argued that approximately one third of the population experiences tinnitus ... |
Primary classical hodgkin's lymphoma (hl) of the gastrointestinal tract (git) are rare lymphoproliferative neoplasm representing less than 5% of git lymphomas, predominantly confined to the small intestine . Diagnosis of the primary lesion requires the lack of peripheral or mediastinal lymphadenopathy, normal white blo... |
Gastrointestinal stromal tumors (gists) are mesenchymal tumors that may develop anywhere within the gastrointestinal tract . They are defined as cd117-(c - kit) or cd34-positive spindle cell tumors and are derived from interstitial cells of cajal . The most common site of growth is the stomach, accounting for 6070% of ... |
Live intact tissues can be imaged using two - photon laser scanning microscopy (tplsm) either intravitally with the animal anesthetized or by isolating and imaging tissue explants maintained in oxygen - supplemented media at controlled temperature (15). Using a femtosecond pulsed - emission laser and near infrared ligh... |
Japan is one of the world s fastest aging societies, and the increase in the elderly disabled requiring long - term care is becoming a social problem . According to the long - term care insurance report 2012 issued by the ministry of health, labour and welfare (mhlw), 5,306,000 people, including the bedridden elderly, ... |
Sbp is a common and severe complication in cirrhotic patients (3), and is the major cause of mortality and morbidity among them (4). Bacterial infection due to complications such as hepatic encephalopathy or hepatic failure, disruption of homeostasis, and renal insufficiency are common causes of the increased morbidity... |
Large amounts of undesirable behavior results in suicidal behavior that is an expression of a specific form of vulnerability . Patients with hopelessness systematically misconstrue experiences in a negative manner and tend to anticipate dire consequences for their problems . The present study was carried out with the o... |
In recent years, increasing attention has been devoted to the synthesis of various nanostructured batio3, such as nanoparticles, nanocubes, nanorods, nanowires, and nanotubes, because of the dependence of their ferroelectric and piezoelectric properties on the dimension and size, which is essential for realizing nanosc... |
One of the major reasons for patients presenting at a primary care practice is pain; according to surveys, around 40% of patients consult their family doctor mainly owing to pain, and 2040% of those have been suffering from pain for more than 6 months [1, 2]. High prevalence rates for chronic pain have been reported in... |
Asthma is one of the most prevalent diseases in children and adolescents worldwide and the leading reason for inability in children . The prevalence of asthma has been reported variously in iran (4 - 7%) and worldwide (8 - 12%). Also, the prevalence in children is so growing worldwide that it has increased by 50% in di... |
After colostomy, the nonfunctioning intestinal segment presents inflammatory alterations comprising a nosological entity known as diversion colitis (dc).1 the preferred treatment for dc is intestinal transit reconstruction which, in most cases, resolves the inflammatory process.2 ma et al.3 analyzed 21 cases of dc and ... |
Zfin (http://zfin.org) is a curated database of zebrafish genetic and genomic data including genes, mutants, transgenic lines and constructs, genotypes, phenotypes, gene expression, anatomical structures, orthology, nucleotide and protein sequences and reagents such as morpholinos and antibodies . A table illustrating ... |
The use of 18-fluorodeoxyglucose positron emission tomography - computed tomography (18-fdg pet / ct) in the field of oncology is well - established; however, 18f - fdg is not tumor specific . Aside from physiological uptake fdg knowledge of these fdg - avid non - malignant lesions is essential for accurate pet interpr... |
The ciliate diploplastron affine is a common species of rumen fauna in the domesticated ruminants (dogiel 1927). To date, the fibrolytic properties of this protozoan were studied by coleman (1985) whereas its ability to digest and utilize starch is not well known . The objectives of the reported studies were to examine... |
Wild - type (c57bl/6j) and sod1 (b6.cg-tg(sod1*g93a)1gur/j, stock #004435) mice were obtained from jackson laboratories (bar harbor, me, usa). Intraocular pressure elevation was induced by anterior chamber microbead injections as originally described by sappington et al . However, we applied a recently described modifi... |
Anaphylaxis is a medical emergency that is manifested by a broad spectrum of signs and symptoms that can be similar to those of other diseases . Vascular collapse and bronchospasm are hallmarks of this condition, but neither is universally present . Other findings, such as flushing or urticaria, are easily overlooked i... |
Issues pertaining to biology and therapy of malignancies occurring amongst adolescent and young adults (aya) have largely remained neglected till last few years when data emerging from epidemiology and outcome registries suggested the need for active research in this field . Over the years, improvements in the understa... |
Surfactant - like peptides (slps) have a remarkable ability to self - assemble into different nanostructures, primarily due to their amphiphilic nature . For example, they can aggregate into high aspect ratio structures while displaying bioactive peptides . Slps are a class of amphiphilic peptide comprising a headgroup... |
In the mid 1960s, brinley presented a novel plotting method to consider the relationship between response times in young and older adults across a variety of tasks with varying levels of cognitive difficulty . The average response times for both the young and older groups of adults on each task was placed on a scatter ... |
Some cyclists use the bicycle as a means of transportation, others ride for recreation, and some are competitive cyclists . The repetitive movements of cycling put cyclists at a risk of overuse injuries, particularly to the leg joints (knee and ankle). During 1985, about 8.36% of causalities seen in the emergency room ... |
Our patient was a 76-year - old man with a coronary artery bypass graft due to unstable angina . During the postoperative period, a blood gas analysis showed a paco2 concentration of 45 mmhg, pao2 concentration of 63 mmhg, and a ph of 7.40 during intermittent mandatory ventilation at a rate of 12 breaths per minute, a ... |
Over the past two decades, numerous studies have provided evidence that sleep enhances memory consolidation . It has been initially shown that consolidation of declarative / episodic memories is enhanced by early sws - rich periods of sleep whereas procedural memory rather benefits from late sleep during which rem slee... |
Type 2 diabetes mellitus affects about 5% of the german population.1 eighty percent of patients with type 2 diabetes are treated with diet or oral antiglycemic drugs (oads).2 for successful treatment of patients with diabetes, we have different therapy options, such as modification of eating behavior and physical exerc... |
As indicated in a recent systematic review relating to canada's physical activity guidelines for older adults, exercise interventions (comprised of aerobic and strength training) in older adults can maintain or improve functional abilities . Less is known about the role of flexibility in the maintenance or improvement ... |
In each country, the government and health system are responsible for providing sufficient and cost - effective health and curative care . Moreover, increasing the accessibility and utilization of health services are critical for improving health systems . Primary health care is largely financed and delivered by public... |
Recent technological advances in endoscopy have supported a flood of new diagnostic methods, collectively reported as consensus terminology . The narrow band imaging (nbi) used in this study fits into the well - studied image - enhancing endoscopy (iee) category [225] as autofluorescence imaging (afi) [2124], as distin... |
Immunosuppressive agents are the major therapy in focal segmental glomerulosclerosis (fsgs) and in aplastic anemia, and therefore it generally believed that immunological mechanisms contribute to both diseases . The pathogenesis of fsgs is unknown but appears to be the result of a lymphokine or cytokine, which leads to... |
The increasing incidence of complex percutaneous coronary intervention (pci) is accompanied by risks of device fracture or dislodgement . Guide wire fractures during pci are very rare, but in such cases, life - threatening complications such as embolization, thrombus formation and perforation may occur . Although, in m... |
In china, hepatocellular carcinoma (hcc) is the fifth most common malignant cancer and the third leading cause of cancer - related mortality . About 90% of patients with hcc also have various levels level of liver cirrhosis, mainly caused by chronic liver disease after hepatitis b and c, especially in patients associat... |
Osteomas are the most common benign tumors of the nose and paranasal sinuses, with an incidence that ranges between 0.43 - 1% (1, 2). They occur most commonly within the frontal sinus (52%), followed by the ethmoid (22.0%), the maxillary sinus (5.1%), and the sphenoid (1.7%) (1). It is very rare for an osteoma to arise... |
Systemic sclerosis (ssc), or scleroderma, is a chronic multisystem disorder of small vessels and connective tissues characterized by diffuse fibrosis of the skin and internal organs, most frequently the lungs and gastrointestinal tract . The disease has a 3:1 female predilection and typically occurs in the third to fif... |
The movement of organelle dna to the nucleus has been, and remains, a driving force in fashioning eukaryotic genomes (timmis et al . 2004; kleine et al . Early on in both mitochondrial and plastid evolution, there was a massive migration of organelle genes to the nuclear genome (gray et al . 2009); thus, present - day ... |
Statins are used to lower serum cholesterol concentrations in the primary and secondary prevention of cardiovascular disease (1). In randomized trials, the use of statins has demonstrated 30% reductions in atherosclerotic end points without serious morbidity . The pleiotropic effects of statins, indirectly related to c... |
It refers to abnormal hearing of sound heard during metabolism and not from an external sound source . The most common cause of vibratory tinnitus is intracranial vascular disease, such as aneurysm and arteriovenous malformation.1) the authors performed excisional biopsy on pulsatile lip masses of 46 year old male . A ... |
Falls in adults pose a major health concern, are a well - known public health problem,1 and are the main cause of injury, hospitalization, disability, poor quality of life, depression, and mortality in older adults.2,3 about 30%40% of adults in the usa report falling at least once per year,4 but less than half discuss ... |
Colorectal cancer (crc) is the fourth most commonly diagnosed malignant disease worldwide, with over 1 million new cases and approximately 5,00,000 deaths each year . Incidence and deaths from this cancer are generally increasing, most of all in the developed world and urban areas of the developing world . Age adjusted... |
Though the majority of us physicians have seen a patient receive poor quality health care due to patient race or ethnicity, responding to these witnessed practices can be challenging.1 many faculty may be uncertain about the link between an observed behavior and clinical outcomes.15 faculty often avoid giving feedback ... |
Musculoskeletal disorders (msds) are prevalent among workers in the construction industry which warrants heavy physical work, often necessitating inappropriate working postures for prolonged periods, which significantly increases morbidity and considerably decreases the work ability . The brick manufacturing industry i... |
Among the different types of forearm motor activities required in simple day - to - day tasks, two primary types of movements required are closing and opening of hand for grasping and releasing objects of different sizes respectively . Research shows that about 80% of stroke survivors lack in movement control and coord... |
Our institutional review board approved our retrospective study with a waiver of informed consent . From september 2003 to july 2006, we enrolled 199 patients who underwent integrated pet / ct and surgical staging and were diagnosed with stage t1 nsclc at ct (retrospective review and reanalysis of all ct data obtained ... |
We present a patient who developed pneumomediastinum after an elective bilateral preperitoneal laparoscopic hernia repair . As newer approaches to inguinal hernia repair are performed, newer complications of these techniques are being encountered . Laparoscopic approaches to inguinal hernia repair have been described w... |
We retrospectively reviewed the charts of patients on the waiting list for kidney transplants in our unit . The analysis was performed until december 2007 and included 342 patients from whom routine complete abdominal ultrasound results could be recovered . This ultrasound is performed on all patients as part of the in... |
Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea . A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type . We present a case of systemic sclerosis in a 50-year - old female who developed nodular scleroder... |
Seven - transmembrane receptors are a family of signaling proteins that bind hormones, autacoids, and neurotransmitters to mediate a myriad of cellular functions . Like all proteins, these exist in collections of tertiary conformations called protein ensembles; receptors sample these conformations according to changes ... |
Identification is a matter of paramount importance in any crime investigation . Even though dna and fingerprints are the time - tested methods, these evidences are not always available at the investigation sites . In such circumstances, it is necessary to apply different and less - known techniques . A new area of inve... |
However, the incidence of ivh among vlbw infants has declined in the past few decades, from 40 - 50% in the early 1980s to approximately 20% in the late 1980s, then remaining relatively stable for the past two decades . Ivh occurs in nearly half of infants born at extremely low birth weight (500 - 750 g). Infants who s... |
Patients presenting with recent onset of low back pain and dermatomal sensory loss are often evaluated for common entities including disc herniation, degenerative lateral recess stenosis, nerve sheath tumor, and meningioma . Described herein is a patient presenting with such symptoms who was found to have an extradural... |
Composite resins are susceptible to various degrees of discoloration after prolonged exposure to the oral environment. [24] three types of discolorations are generally described: external discoloration due to the accumulation of plaque and surface stains (extrinsic stain), surface or sub - surface color alteration impl... |
Currently, more than 150 000 partial or complete hiv genome sequences are available in the central hiv database at los alamos national laboratory (1); these data are crucial for the development of drugs against aids . Analysis of hiv sequence data is challenging, however, since hiv is among the most genetically variabl... |
A literature search using the title terms metabolic syndrome and diabetes was conducted in pubmed . We limited the search to articles that were written in english . Because the who was the first to release its definition, in 1998, we started our search for articles published that year and continued through april 2008 .... |
Patients with heart failure (hf) are suggested to have a diabetes mellitus (dm) prevalence of 841%,1 which is associated with increased mortality and morbidity.2, 3 treatment of dm in hf patients is controversial, because many contemporary therapies used for dm treatment, including thiazolidine, are contraindicated in ... |
Evolution and speciation are believed to be driven in large part by the insertion of transposable elements (tes) within eukaryotic genes . The tes can integrate into a gene with either a forward or reverse pattern according to the transcription directionality of the inserted gene and the transposase gene . When inserti... |
Acute renal failure is a frequent feature at diagnosis of multiple myeloma (mm). It is present in 2055% of patients with a newly diagnosed mm, among whom 23% require dialysis . Renal impairment is a poor prognostic factor in patients with mm as it is associated with an increased morbidity and early mortality rates . Ho... |
Its causes are varied, but in all cases it is characterized by the appearance of local acute or chronic inflammatory changes occurring in the wall of the trachea . These changes lead to degradation over time and pathological restructuring of constituent structures and their replacement by fibrous tissue . They are ofte... |
Yttria - stabilized tetragonal zirconia polycrystal (y - tzp) ceramic has extensive applications in restorative dentistry due to excellent mechanical properties and biocompatibility . Zirconia computer - aided design and computer - aided manufacturing (cad / cam) systems have enabled the fabrication of y - tzp dental c... |
Low - back pain is one of the most common human morbidities worldwide, which is damaging individually, socially and economically . Most of the low - back pains are non - specific though specific ones need more complicated and more expensive treatments . Sciatica or lumbar radiculopathy is one of these specific low - ba... |
Genital self mutilation is a rare and a severe form of self - injurious behavior . It is usually described in psychotic disorders, mostly in schizophrenia as a result of delusions and hallucinations. [13] in most cases, penile mutilation is common . Risk factors of genital self mutilation include commanding hallucinati... |
Obesity is a chronic metabolic nutritional disorder that has increased at an alarming rate in the last 20 years . In the us, 68% of the adults (age 20 years) and 18% of children (219 years) are either obese or overweight as per the national health and nutrition examination survey [2, 3]. Incidence of obesity is associa... |
Patients older than 70 years remain one of the fastest growing populations . In the usa alone this group increased from 21.1 million in 1990 to over 25 million in 1999, and is projected to reach nearly 36 million people by the year 2020 . With this in mind, the number of elderly patients presenting with an st - segment... |
The use of titanium for dental implants and metal ceramic restorations, such as cast restorations or partial dentures, has increased over the last years because of their biocompatibility and optimum mechanical properties . However, low bond strengths between titanium and composite veneering systems have been reported .... |
Combined hepatocellular and cholangiocarcinoma (chcc - cc) is an uncommon subtype of primary liver cancer [1, 2]. The disease was first described in 1949 by allen and lisa and has been defined as the intimate intermingling of both a hcc component and cc component (2). Allen and lisa described three groups, type a with ... |
Microarray analysis has been shown to be of crucial importance for the understanding of the genetic etiology of intellectual disability (i d). With this technique, numerous (de novo) copy number variations have been discovered leading to several circumscribed microdeletion syndromes.1,2 especially in patients in whom n... |
Myxomas are the most common benign cardiac tumors, typically originating from the left atrium . The right atrium is the second most common site where myxomas originate, accounting for 7%12% of cases . Only a few cases of myxomas arising from the right ventricle have been reported . In these cases, myxomas originating f... |
A 62-year - old woman was hospitalized for the further evaluation of her progressive chest discomfort for 10 days . The patient had undergone total thyroidectomy 20 years earlier, and she has been managed for hypothyroidism since then . Seven years prior to admission, she was diagnosed with and managed for angina pecto... |
Language can be counted as the first cognitive enhancement, and the invention of writing also dramatically improved our cognitive ability to remember, to learn, and to communicate. Today, with the aid of recent phenomenal development of biomedical technology, we are witnessing the emergence of more direct biological co... |
S. oneidensis mr1 cultures were grown aerobically in lb (30 c, 200 rpm, 16 h) to an optical density od 600 nm>1 . This culture (1 ml) was used to inoculate lb (50 ml) supplemented with 50 mm lactate and 25 mm fumarate in a 50 ml falcon tube . The top of the tube was fastened shut and the culture was grown overnight (0 ... |
Stroke involves rapid loss of brain function resulting from a disturbance in the blood supply to the brain; it often profoundly affects upper limb stability and movement capacity . Stroke is the third leading cause of death worldwide, and it is the leading cause of severe disability in patients in the developed world1,... |
Because of the aging population, the number of patients with age - associated joint disorders has been increasing in japan . These disorders are a major factor in the reduction of the activities in the daily lives of the middle - aged . In particular, the number of patients with knee osteoarthritis (oa) has been rapidl... |
We evaluated the performance of surveillance case definitions for zika virus disease recommended by the cste, who, paho, ecdc, and the singapore moh by using a cohort of 359 adult patients with suspected zika virus disease who came to the institute of infectious diseases and epidemiology, tan tock seng hospital, singap... |
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