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Ampk is a heterotrimeric protein that consists of an, and subunit in equal stoichiometry . The subunit constitutes the catalytic domain, conferring kinase activity, while the subunit enables ampk to monitor cellular energy status through two amp / atp binding domains, referred to as bateman domains, that bind amp or at... |
Single - walled carbon nanotubes (swcnts) dispersed in aqueous media hold great promise for exciting applications in chemistry, biology, and nanomedicine . Central to these applications is the stability of these nanoscale dispersions in aqueous media . Various reagents or perturbations have been applied to control the ... |
Sleep behaviors are among the most common concerns that bring parents of young children to their physicians . A child who goes to bed unwillingly or wakes frequently during the night can be highly disruptive to a family . As a rule, the frequency of night waking starts in 100 percent of newborns and tails off to approx... |
Health services and health policy research can be based on qualitative research methods, especially when they deal with a rapid change and develop a more fully integrated theory base and research agenda . However, the field must be with the best traditions and techniques of qualitative methods and should distinguish th... |
Safety and efficacy of pharmaceuticals are two basic problems with importance in drug therapy . Instability of pharmaceuticals can cause a change in physical, chemical, pharmacological, and toxicological properties of the active pharmaceutical ingredients (api), thereby affecting its safety and efficacy . Hence, the ph... |
Traumatic lumbar spondylolisthesis is rare disease and in the literature, different surgical approaches, including anterior, posterior, or combined approaches (posterior and anterior) are used to treat the lesion . We treated a case of traumatic lumbosacral spondylolisthesis using posterior approach and the patient sho... |
Primary pulmonary histoplasmosis is a lung disease caused by the dimorphic fungus histoplasma capsulatum, with a worldwide incidence . It is endemic in certain areas of north america, and was first reported in china in 1958 (1). The severity of this mycosis is dependent upon the number of inhaled fungal particles and t... |
The aim of the danish gynecological cancer database (dgcd) is to achieve the greatest possible knowledge regarding examination, treatment methods, and results within the field of gynecological cancer in denmark . Dgcd is by definition nationwide: a clinical quality registry where a minimum of 90% of the relevant patien... |
Nonalcoholic fatty liver disease (nafld) is the most prevalent cause of chronic liver diseases . This disorder occurs because of the pathologic accumulation of fat (mainly triglycerides) in the liver . It is estimated that in iran, 7% of children and 35% of adults are affected . Until now results of these studies have ... |
Following endodontic treatment, there is a decrease in the fracture resistance of the teeth . This is also seen after the preparation of wide mesio - occluso - distal (mod) cavities . An ideal restoration for a tooth is able to maintain the aesthetics and function, preserve the remaining tooth structure and prevent the... |
Chlamydophila pneumoniae is a common etiological factor of the respiratory tract infections, including pharyngitis, bronchitis, and pneumonia . It is estimated that c. pneumoniae is responsible for pneumonia in approximately 10% of cases, and for bronchitis and sinusitis in approximately 5% of cases . The main symptoms... |
Gastric cancer is still one of the most frequent causes of cancer - related deaths . Although its incidence has decreased in recent years, it is still high in eastern asia, including china . Familial gastric cancer (fgc) has a lower incidence in western countries, only 1%3% of patients have been diagnosed as family gas... |
Breast cancer, which has the highest incidence and mortality rate of women cancers globally, imposes a significant disease burden in developing countries . Among breast cancer risk factors, dense breasts found on mammography due to breast epithelium and stroma are known to be a potent risk factor, raising breast cancer... |
Blood - questing mosquitoes mainly rely on olfactory cues to locate their hosts (takken, 1991; costantini et al ., 1996; takken and knols, 1999). Funestus giles, these cues are strongly reminiscent of those released by humans i.e., the principal source of the mosquitoes blood meals (gillies and coetzee, 1987). Odorants... |
The occurrence of carcinoma in the external auditory canal (eac) is rare, with an annual incidence of one per one million people, accounting for less than 0.2% of all head and neck cancers . Verrucous carcinoma is a well - differentiated variant of squamous cell carcinoma, which is a low - grade malignancy and describe... |
Acute liver failure (alf) is characterized by an initial devastating hepatic insult followed by gross parenchymal dysfunction, which leads to a multitude of systemic organ failures due to the missing metabolic homeostasis normally provided by the healthy liver . The most common causes of alf are viral hepatitis, idiosy... |
For the past 40 years the porcelain - fused - to - metal systems have been extensively used in fixed partial dentures (fpds) and still represents the gold standard.1 the advantages of the pfm systems are to combine the fracture resistance of the metal substructure with the esthetic property of the porcelain . However, ... |
Recently, there has been a growing worldwide interest in marathon running due to recognition of the positive effects of endurance exercise on health and physical strength . In particular, an increasing number of amateur runners are participating in recreational 10- and/or 21-km marathons, because the physiological dema... |
Peripheral blood monocytes were isolated from three buffy coats (blutspende zrich, zurich, switzerland) by density gradient centrifugation (ficoll - paque plus (ge healthcare)) and enriched for co - culture assays using human monocyte isolation kit ii (macs, miltenyi biotech). The breast cancer cell lines mda - mb-231 ... |
The genus pseudoalteromonas was described by gauthier et al . And represents a clade of marine bacteria defined on the basis of 16s rrna gene sequence data . Originally many of the pseudoalteromonas species that are discussed in this review were members of the genus alteromonas [5, 77] but alteromonas was taxonomically... |
Abelson murine leukemia viral oncogene large tumor suppressor runt - related transcription factor peroxisome proliferator - activator receptor gamma 2 transcriptional enhancer activator domain yes - associated protein based on a number of criteria, certain genes are categorized as oncogenes whereas the genes that oppos... |
Extranodal lymphoma of mucosa - associated lymphoid tissue (malt) can occur throughout the body . While the gastrointestinal tract is the most common site of involvement, research over the past several decades has shown that cancers such as lymphomas are a genetic disease and that particular genetic mutations can lead ... |
Self - expandable metal stents (sems) are uncommonly used for benign colonic disease because of their lack of removability and their high rate of migration . Histology had confirmed the presence of diverticular disease in the sigmoid colon along with inflammatory changes in the tubes, ovaries and part of the uterus, wh... |
We constructed a decision tree cost - effectiveness model for a target population of 163,000 women who at the time of the intervention are sexually active with a male partner, fertile, not desiring pregnancy within the next 12 months, and not using permanent contraception methods (e.g., tubal ligation and vasectomy) (t... |
We evaluated a subset of 1,759 from 2,031 look ahead (action for health in diabetes) participants generally corresponding to the first half of enrollees from 15 of 16 participating clinic sites who had hs - crp determinations and fitness data at baseline and 1 year . Loss to follow - up at 1 year was very low in our el... |
It is a labile protein which is comprised of 393 amino acids, folded and unstructured regions that function in a synergistic manner and responsible for induction of cell cycle arrest or apoptosis based on the cellular damage, stress, and cell type . In cell cycle, it acts as a transactivator that negatively regulates c... |
In 2014, researchers and medical personnel celebrated the 25th anniversary of the discovery of hepatitis c virus (hcv). The first publication on the new virus genome appeared in 1989.1 after that, comprehensive study of new hcv and related disease began, including diagnostics, pathogenesis, and epidemiology . The offic... |
The risks of exaggerated haemodynamic responses during anaesthesia and surgery and development of awareness has been a cause for concern in patients undergoing caesarean section, concurrent to the practice of avoidance of sedatives and anxiolytics until delivery . Laryngoscopy and intubation causes exaggerated haemodyn... |
Autonomic dysfunction presents with heterogeneous clinical features and is a multi - system condition affecting nervous, cardiac, gastrointestinal, musculoskeletal and vocal cord function . Autonomic dysfunction is often a result of an imbalance in the sympathetic and parasympathetic nervous system . This case study de... |
Congenital adrenal hyperplasia (cah) is an autosomal recessive adrenal steroid synthesis disorder that is transferred genetically and is characterized by increased adrenocorticotropic hormone (acth) secretion due to glucocorticoid and mineralocorticoid deficiency . An increase in acth synthesis can result in hyperplasi... |
Diabetic retinopathy (dr) is a major microvascular complication of diabetes accounting for its leading cause of irreversible blindness worldwide . Assessing the risk factors of dr, particularly modified risk factors, is important for early intervention to reduce the onset and progression of dr . These studies consisten... |
This cross - sectional study included 229 patients who applied to sleeping centers under the supervision of the neurology and chest diseases clinics of kayseri education and research hospital, kayseri, turkey between june and august 2013 and were given a date for polysomnography (psg) for the first time . We used the s... |
Over the past decade, dementia with lewy bodies (dlbs) has arguably become the second most common form of neurodegenerative dementia behind alzheimer's disease (ad). In addition to progressive decline in cognition, dlb is characterized by fluctuations in cognition with variations in attention and alertness, recurrent f... |
When genetic susceptibility testing for hereditary breast and/or ovarian cancer was introduced in the nineties, professionals were concerned about the psychological consequences of learning one's genetic status . Women carrying a brca1/2 mutation have to deal with considerable health risks [1 - 3] and are confronted wi... |
The amount of body fat may significantly change over the seasons, particularly in latitudes away from the equator, where seasonal changes in climate, temperature and duration of daylight are greater . These lead to changes in availability of certain foods and in individuals feeding habits and outdoor activity (resultin... |
The lumbar multifidus (lm) muscle is an important local stabilizer of the spinal segments1 . Its main function involves stabilizing the neutral zone of the lumbar spine2 and controlling the extension moment of the lumbar spine3 . A previous study showed that the lm was atrophied on the side of pain in patients with acu... |
Acute renal failure (arf) or acute kidney injury includes a wide range of disturbance in kidney function . Renal ischemia / reperfusion injury (riri) which occurs mainly in different clinical circumstances such as renal transplantation is responsible for high morbidity and mortality rate . Endothelin-1 (et-1) as one of... |
Chronic total occlusion (cto) angioplasty is one of the most challenging procedures remaining for the interventional operator . Recanalizing ctos can improve exercise capacity, symptoms, left ventricular function and possibly reduce mortality . Many strategies, such as escalating wire, parallel wire, see - saw, contral... |
Propofol is a commonly used drug for induction of anesthesia because of its rapid onset and short duration of action, easy titration, and favorable profile for side effects . However, despite these positive attributes, about 28 - 92% patients experience pain on injection of propofol, with one of three patients reportin... |
Ameloblastic fibro - odontoma (afo) is a benign, slow growing, expansile epithelial odontogenic tumor with odontogenic mesenchyme . It may inhibit tooth eruption or displace involved teeth although teeth in the affected area are vital [13]. Radiography shows a well - defined, radiolucent area containing various amounts... |
The application of fibrinolytic therapy in acute myocardial infarction is generally practiced to reduce the associated morbidities; however, there are rare reports of pulmonary hemorrhage attributed to the use of fibrinolytic therapy throughout the literature . In this case report, we present a 45-year - old man who de... |
The importance of the judicious use of clozapine in patients with schizophrenia in clinical practice is brought to an even sharper focus when it has to be used in combination with other agents that cause myelosuppression, for example, chemotherapy and radiation treatment . Chemotherapy can cause can cause marked bone m... |
The surgical removal of an impacted mandibular third molar may injure the inferior alveolar nerve (ian). Neurological complications resulting from this kind of surgery may arise from an insufficient diagnosis of the surrounding anatomical structures or the applied surgical technique . The incidence of these neurologica... |
Since the clinical severity ranges from mild to potentially life - threatening, major efforts are currently being made to develop methods to detect patients with these diseases in the neonatal period . In fact, making a diagnosis before vaccines or blood products are administered, as well as before the infection develo... |
Epidermal nevus with hemifacial hypertrophy can occur in schimmelpenning syndrome, phakomatoses pigmentokeratotica, proteus syndrome and type 2 segmental cowden disease . The epidermal nevus syndromes are a group of congenital syndromes comprising epidermal nevi in conjunction with central nervous system (cns), ocular,... |
It represents the most significant parasitic disorder in the mediterranean countries and leads to major problems through unfavorable effects on the public health and national economy . Hydatid cyst most commonly occurs in the young populationand the herds of sheep - goats raised by the countries and the relation betwee... |
Skeletal complications are a major cause of morbidity and mortality in men with prostate cancer (cap). Several factors contribute to the adverse skeletal health in these patients, e.g. Age related osteoporosis, accelerated bone turnover associated with the disease, metastatic bone lesions and androgen deprivation thera... |
Essential tremor (et) is a common neurological condition which increases with the age of the population and contributes to significant disability in most affected patients . Previous cross - sectional studies have shown that patients with et may have minor cognitive deficits on formal testing although most of these old... |
This was a single - center, retrospective comparative study of eyes treated with the ex - press glaucoma filtration device under a partial - thickness scleral flap in african american and white glaucoma patients . The study protocol was approved by the institutional review board, and informed consent was obtained befor... |
Embryonic development relies upon the precise control of genetic programs to create complex tissues and organs . Mutagenesis screens and the sequencing of multiple genomes have revealed an extensive list of patterning genes, many of which are expressed in a tissue - specific manner within the developing embryo . One of... |
Complex regional pain syndrome (crps) is a chronic condition characterized by severe pain and motor, sensory, autonomic, and trophic disturbances 1, 2, 3, 4, 5 . The severity of symptoms associated with crps is unrelated to the severity of the trauma that caused the condition 1, 3, 4, 6 . The classic presentation of cr... |
There are many reports of paraganglioma diagnosed on fine needle aspiration cytology (fnac) in the literature . Although fnac of a suspected paraganglioma is contraindicated in view of the hypertensive crisis after fine - needle aspiration, this tumor can be an unexpected finding in neck mass fnacs performed in unsuspe... |
Vegf signaling pathways drive the development of the vascular system by regulating three distinct processes: vasculogenesis, angiogenesis, and arteriogenesis . Embryonic vascular development is initiated by vasculogenesis when vegf induces differentiation of endothelial progenitors to endothelial cells that then form a... |
Anthocyanins are naturally occurring polyphenolic compounds that give the intense color to many fruits and vegetables such as berries, red grapes, purple sweet potato, and red cabbages [1, 2]. In contrast to the other flavonoids, anthocyanins carry a positive charge in the central ring structure and are thus cations . ... |
A 42-year - old italian man, who had been living in nigeria because of his job since two years, was urgently repatriated following diagnosis of acute plasmodium falciparum malaria . Fourteen days after anti - malarial treatment started, with quick resolution of fever, he suddenly complained of acute left flank pain . L... |
The scaphoid fossa, triangular fossa of the antihelix, and the cymba concha are typically involved . Various terms for this condition are endochondral pseudocyst, intracartilaginous auricular seroma cyst, cystic chondromalacia, and benign idiopathic cystic chondromalacia . Males are commonly affected and the mean age o... |
The prevalence of diabetes mellitus in india, where the total population is 1.25 billion people, is roughly 7.1%, and diabetes is four times more common in urban, compared with rural, india [1, 2]. The proportion of gross domestic product expenditure on health care in india by the government is a meager 1.3% . The econ... |
Dr . Bawaskar was born in a small village with a population of 500 in rural maharashtra to a poor farmer in the early 1950s . One who is courageous; it was years later that he proved that no other name would have suited him better . His father recognized that education was the only tool that would liberate the family f... |
The term odontome by definition alone refers to a tumor of odontogenic origin . In a broad sense, it means a growth with both the epithelial and mesenchymal components exhibiting complete differentiation, with the result that functional ameloblasts and odontoblasts form enamel and dentin . This enamel and dentin were u... |
Allogeneic hematopoietic stem cell transplantation (allo - hsct) is currently one of the most effective methods of treatment for both hematological malignancies and nonmalignant disorders; it also represents a promising therapeutic approach in some solid tumors . Unfortunately, allo - hsct is not exempt from serious co... |
Systemic sclerosis (ssc) is an autoimmune disease of unknown etiology that is characterized by vascular dysfunction and cutaneous and visceral fibrosis . Women are more frequently affected than men at a ratio of 4: 11, and the peak incidence occurs in the fourth and fifth decades of life . The prevalence appears to be ... |
The effects of smoking habits of mother during pregnancy have been studied in the past century or so in various communities and different cultures . One of the earliest studies (1) in birmingham, uk, reported in 1959 shows that infants of mothers who smoked regularly during pregnancy were on the average more than 170 g... |
Gingival hyperplasia is a bizarre condition causing aesthetic, functional, psychological and masticatory disturbance of the oral cavity . Investigations are in evolution to establish the genetic linkage and heterogeneity associated with it . This condition may manifest as an autosomal - dominant or, less commonly, an a... |
Over the last 2 decades, various molecular imaging technologies, including positron emission tomography (pet), computed tomography (ct), single photon emission computed tomography (spect), magnetic resonance imaging (mri), ultrasound, and fluorescence reflectance imaging, have revolutionized the way that we investigate... |
The immune system is delicately balanced between immunity and tolerance to protect the host from pathogens while minimizing local damage to tissues . Indoleamine 2,3-dioxygenase (ido) is an endogenous molecular mechanism that contributes to this immune regulation in a variety of settings . Ido seems to be critical in l... |
Given a renewed public awareness following a recent measles outbreak in iowa, several pregnant women inquired about their measles immunity . While confirmation of measles immunity is not routinely performed, determination of rubella immunity is a routine antenatal test in the united states . Consequently, we questioned... |
Royal free ethics committee for retrospective publication of patient data . Written informed consent for publication was obtained from the patients . Ma beckles and t wagner not commissioned; peer - reviewed by vaishali sanchorawala and kaushik sanyal royal free ethics committee for retrospective publication of patient... |
The flaviviridae family includes approximately 80 members divided into four genera: flavivirus, pestivirus, pegivirus, and hepacivirus . The flavivirus genus can be further divided into four categories: mosquito - borne, tick - borne, no known vector (nkv), and insect - specific (isf) viruses . Mosquito- and tick - bor... |
Advancements in systemic chemotherapy for colorectal cancer (crc) have improved the clinical response rate and expanded the indications for resection to cases that were previously not operable at the initial visit . In addition, the prognosis of patients who undergo radical surgery for metastasis is clearly better than... |
The pathophysiology of rheumatoid arthritis (ra) provides numerous cellular, intracellular, and messenger molecule targets, which can all be addressed by biochemical as well as antibody - based biological therapeutic agents . On the other hand, none of the current therapeutic regimens for ra leads to a long - term 100%... |
Attempts to use national or local surveillance data to estimate the risk for sti transmission between women are limited by the fact that many risk classification schemes have either excluded same - gender sex among women or subsumed it under a hierarchy of other behaviors viewed as higher risk . Moreover, few, if any, ... |
As concerns regarding foot health have risen, foot pressure measurement has been widely used to solve foot problems in patients with foot pain, diabetes mellitus, and rheumatoid arthritis2 . Foot pressure is one of the measurement areas considered most in clinical trials and sports science research, and it has been mea... |
As a cell or a community of cells, a biological system s hierarchical organization allows for structure formation and system functionality . Alteration of biological processes, such as cell cycle1 or cell division,2 may lead to fundamental disorder at the molecular level and induce activation of genetic changes (figure... |
Proliferation and prognosis of human breast cancer has been dependent on several factors such as their hormone or estrogen - responsiveness, expression of estrogen receptor (er) and other genes . Hormone - independent (er negative) tumors were more aggressive and development of clinical protocols for treatment of these... |
Prominence of the anterior inferior iliac spine (aiis) at the level of the acetabular rim has been recognized as a potential cause of hip impingement (aiis subspine impingement). Accordingly, arthroscopic resection of the bony projection has been reported and has become a commonly performed procedure . The aiis is also... |
Pyoderma gangrenosum (pg) is a rare inflammatory disease of the skin often associated with systemic inflammatory disease or immunodeficiency . Although rare, it is known to occur following trauma or operative procedures . To date nine cases we report a delayed presentation of pg in a patient undergoing mitral valve rep... |
An elevated arterial pressure is an important public health problem in developed countries, as well as in india . Hypertension is the most common modifiable risk factor for coronary artery disease, stroke, congestive heart failure, end - stage renal disease, and peripheral vascular disease . Metabolic syndrome (ms) is ... |
Los intentos a la hora de ayudar a dejar de fumar rara vez resultan mejores que simplemente efectivos parcialmente . Describir un estudio observacional de un programa ya existente y de gran xito para dejar de fumar, ofrecido por un consejero de salud como intervencin primaria . Los componentes bsicos del diseo del prog... |
Body mass index (bmi) is the most commonly used anthropometric method to define human obesity . Bmi is a complex trait affected by many environmental (eg, diet, age, physical activity) and genetic factors, with heritability estimates that vary from 4080% in twin studies, 2050% in family studies and 2060% in adoption st... |
As part of continuous national avian influenza virus surveillance, we performed a monthly collection of cloacal swabs from various poultry species (chicken, duck, goose, quail, and pigeon) at a wholesale live - bird market (lbm) in yangzhou, jiangsu province, in eastern china . Birds offered for retail sale in the lbm ... |
Age- or injury - induced muscle weakness leading to frailty is a major public health problem that is predicted to escalate in the future as the number and proportion of older adults increase in the general population (berger and doherty 2010). There is an unmet need for therapeutic strategies that can slow the effects ... |
Refractory status epilepticus (rse) is defined as seizures that are nonresponsive to adequate initial anti - epileptic therapy and require a continuous infusion of an antiepileptic medication or administration of inhalation anesthetic agent to stop the seizure activity . The care of children with rse is largely based o... |
Treatment of cancer pain is one of the most important goals of palliative medicine . However, opioid drugs are the principal agents used to control pain in cancer patients [3 - 5]. If pain in patients with progressing cancer is worsened or constant, medical staff needs to recognize the necessity of increasing the analg... |
The serum anion gap is a helpful parameter in the clinical diagnosis of various conditions . The commonest application of the anion gap is to classify cases of metabolic acidosis into those that do and those that do not have unmeasured anions in the plasma (table 1). In this article, we briefly review the significance ... |
It was estimated that there were 1,500,000 new cancer cases and approximately 560,000 deaths out of cancer in 2009 . Chemotherapy is an important treatment option for patients with cancer, however chemotherapy drugs suffer from numerous problems including nonspecific uptake by healthy tissue, poor circulation times, an... |
Human respiratory syncytial virus (hrsv) is the most important infectious agent of serious acute respiratory illnesses in infants and young children worldwide[1, 2]. Hrsv causes brochiolitis and pneumonia during the first few months of life in the late fall and winter . It is responsible for 1800075000 hospitalizations... |
Disasters are either man - made or natural events (1, 2) whose general consequences include disruption of social and psychological order of communities, destruction of infrastructure and residential houses, deaths and injuries, destruction of assets and properties and disruption of social life of communities (3). Major... |
Skin aging is a complex process that affects all its layers and structure and changes the functional properties of the intracellular matrix . A wide range of biomimetic peptides with different mechanisms of action can be applied to solve this problem . By imitating the action of naturally occurring growth factors and c... |
Dyes are a group of additives used to improve the appearance of foods, textiles, and medicine allowing the homogenizing and the assertion of the color, which is the most important sensory characteristic . Synthetic dyes have been used because they are more resistant to changes in temperature and acidity than natural dy... |
A 44-year - old female without any previous medical history visited our clinic because of the sudden onset of intermittent blurred vision in her left eye . Her best - corrected visual acuity (bcva) was 20 / 22 and fundus examination revealed multiple retinal, preretinal, and subretinal hemorrhages throughout the retina... |
Meningitis is the inflammation of meninges that results in many signs and symptoms . A wide variety of causes include infectious and noninfectious are important . Among the infectious causes of meningitis, some result in chronic meningitis that defines as the signs of meningitis last for weeks to months . In this group... |
Glaucoma is the second leading cause of blindness globally.1 from 1991 to 1999, primary open - angle glaucoma prevalence increased from 4.6% to 13.8% among the elderly.2 its treatment is aimed essentially at lowering intraocular pressure (iop) by eye drop instillations, reserving surgery or laser surgery for the most s... |
Type 1 diabetes (t1d) is an immune - mediated disease in which insulin - producing -cells are destroyed (1). A number of studies have used various forms of immune intervention in recent - onset t1d, usually initiated within 3 months of diagnosis, in an attempt to preserve residual -cell function . We previously reporte... |
The lens of the eye is recognized as one of the most radio - sensitive tissues in the human body, and radiation - induced cataract is a well - known adverse effect . From a review of epidemiologic data, the threshold dose for cataract formation may be judged to be 0.5 gy [1, 2]. A recent draft report by the internation... |
Neuroendocrine tumors (nets) represent a spectrum of rare tumors originating from diffuse endocrine cells throughout the body . In the usa, nets comprise 0.73% of all diagnosed cancers, with an incidence of about 5 cases/100,000/year . The most prevalent of these (55% of nets) are in the gastrointestinal tract; however... |
Recent advances in endoscopic resection techniques, such as endoscopic submucosal dissection (esd), allow for en bloc curative resection of early gastric cancers (egcs) with a minimal risk of lymph node metastasis (lnm), regardless of tumor size or presence of submucosal fibrosis . Esd has several merits over gastrecto... |
The administration of intravenous tissue plasminogen activator (tpa) has been shown to improve prognoses after acute ischemic stroke . This treatment was approved in october 2005 in japan but is still infrequently used because appropriate tpa administration is time dependent and limited to patients within a few hours o... |
Transgenic zebrafish (danio rerio) tg(gfap: egfp)mi2002 and tl strain wild - type zebrafish were maintained using standard husbandry protocols . All procedures were approved by the institutional animal care and use committee (iacuc) at the university of michigan and abided by the arvo statement for the use of animals i... |
At an sbv information meeting, 60 shepherds> 18 years of age were recruited for this study . After obtaining written informed consent, we administered a standardized questionnaire . We collected information about age, sex, sbv infection in their livestock, exposure to sick lambs, frequency of insect bites, personal hea... |
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