text
stringlengths
0
868k
Adrenal glands are a common site for metastatic spread, with autopsy studies documenting their presence in 27%-38% of all fatal malignancies . Various primary tumors can metastasize to the adrenal glands; approximately 50% of melanomas, 30%-40% of breast and lung cancers, and 10%-20% of renal and gastrointestinal tumor...
About 30 years ago, methyldopa and penicillin were the two medications most commonly associated with drug - induced autoimmune hemolytic anemia (diiha). Methyldopa and intravenous penicillin accounted for 67% and 25%, of all drug - induced immune hemolytic anemia, respectively . Currently, most cases of diiha are attri...
Kaposi s sarcoma (ks) is one of the malignancies that is most seen in hiv - positive or immunocompromised patients . The use of immunosuppressant drugs is also associated with the risk of developing ks, especially in kidney transplant patients.1 immunosuppressant drugs may also enhance the risk of ks in other patients ...
A variety of investigations are available for imaging the common bile ducts (cbd) before laparoscopic cholecystectomy (lc), and none has been accepted as gold standard . The guidelines were reasonably well established regarding the management of common bile duct stones in the era of open cholecystectomy . With the deve...
Since 1992, when the vasopressin v2 receptor gene (avpr2) sequence that codes for the v2 receptor (v2r) was first described, more than 200 mutations in the avpr2 have been found in patients presenting with x - linked congenital nephrogenic diabetes insipidus (cndi) [2, 3]. Functional studies of these mutant receptors h...
The way the human organism responds to stress can be positive, such as fast decisions and reactions when facing potential danger (fight or flight)1, 2 . This hormone is an essential corticosteroid which is involved in the restoration of homeostasis,4 but it can be harmful when the organism is exposed to frequent stress...
Wide range of rigid video laryngoscope (vl) are available in the indian market today like mcgrath 5, glidescope, airtraq, kingsvision, truview evo2, cmac, pentax, vt - a100 and so on . The rigid vls are expensive compared with traditional laryngoscopes . The higher price, coupled with the high economic recession is lea...
The amide bond is widely prevalent in both naturally occurring and synthetic compounds . It is increasingly important in pharmaceutical chemistry, being present in 25% of available drugs, with amidation reactions being among the most commonly used reactions in medicinal chemistry . There is considerable interest in the...
To report a case of a young patient with retinitis pigmentosa (rp), essential iris atrophy, and glaucoma . This report presents a case of a 22-year - old female patient with unilateral glaucoma, increased intraocular pressure, increased cup disc ratio, iris atrophy, peripheral anterior synechiae, and bilateral rp . Ess...
Despite the advancement in targeted therapy, treatment of cancer still remains as a huge unmet medical need . Multiple factors, in addition to the complexity of cancer biology, contribute to this unsatisfactory state . Such close tumor - host interactions are vitally important in determining the sensitivity of tumor ce...
Down syndrome (ds), caused by a trisomy of chromosome 21(hsa21), is the most common genetic developmental disorder, with an incidence of 1 in 800 live births . Some of its phenotypes (e.g., cognitive impairment) are consistently present in all ds individuals, while others show incomplete penetrance . A short interval n...
Any variation in root canal morphology should be recognized before or during root canal treatment . An untreated canal, which a clinician fails to detect, may be a cause of failure . Various methods to assess the internal anatomy of root canal systems are: (i) conventional radiographs (ii) canal staining and tooth clea...
Development of caries and wsls around orthodontic bands is a common occurrence following the use of fixed orthodontic appliances particularly in patients with poor oral hygiene . Demineralization occurs when specific bacterial species remain for a long time on the enamel surface . Bacterial metabolites such as organic ...
Water deficit is responsible for the greatest crop losses worldwide and is expected to worsen, heightening international interest in drought tolerance in crops . Plant adaptation to water deficit is the result of many different physiological and molecular mechanisms that interact in a complex manner . Previous studies ...
Sudden hearing loss is a devastating disease for patients and represents a true otologic emergency . The etiologies of sudden hearing loss are many, but only about 1015% of cases have an identifiable cause . Oral steroids have been effective in many patients and currently represent the standard treatment for idiopathic...
Metabolic syndrome (ms) is a combined expression of the characteristics of metabolic disorders including hypertension, insulin resistance, obesity, dyslipidemia, which increase the risk of developing type 2 diabetes mellitus, renal diseases, and cardiovascular disease . Adult ms is prevalent, with an incidence rate of ...
A 14-year - old, spayed female domestic shorthair cat was evaluated because of a right adrenal mass . The referring veterinarian had started treatment for hypokalemia and systemic arterial hypertension . During the initial evaluation the cat was atrophy of the contralateral adrenal and an exaggerated response of cortis...
We collected 456 fecal samples from diarrheic calves (mean age 9 days, median 8 days) from 415 farms in burgundy, france, during december 2005 through september 2008 to screen for these viruses: 1 sample each was collected for 377 outbreaks; 2 and 3 samples were collected for 35 and 3 outbreaks, respectively . Reverse ...
Aerobic exercise is consistently associated with favorable shifts in blood triglycerides and hdl - c; however, data from intervention studies [1, 2] and numerous meta - analyses [36] also support a less well - characterized and variable ldl - c lowering response to exercise training . Beyond ldl - c lowering, lipoprote...
The most effective treatment of end - stage renal disease is kidney transplantation, but a severe donor shortage has significantly limited this treatment . To overcome this profound donor shortage, immunologic barriers historically considered as absolute contraindications to transplantation are being reevaluated . Kidn...
Adverse drug events result in hospital admissions, increased costs, and poor quality of health care.1 prevention of adverse treatment effects is essential for improving patient safety and quality of care.2 with $2.5 trillion in annual spending for healthcare in the us, adverse treatment effects contribute to unnecessar...
One of the three most commonly prescribed blood tests by physicians, urea is the major end product of protein nitrogen metabolism . It is synthesized by the urea cycle in the liver from ammonia which is produced by amino acid deamination . Rediffusion in the distal tubule depends on the urinary flow and is regulated by...
Malignant acrospiroma is which rarely reported, surgical resection is treatment of choice, with radiotherapy for unresectable and margin positive cases . Acrospiroma denotes a group of benign ductal tumors of the eccrine sweat glands that may or may not be connected to the skin, ranging from solitary plaques to exophyt...
A suitable administration is important to recreate and reproduce the structure, profile, form and function of uninjured status . Mandible is the main portable bone of the facial skeleton, and there has been a considerable upsurge in trauma and fracture in a majority of cases . In case if mandible fractures are not hand...
Chronic graft versus host disease (cgvhd) belongs to the most serious and frequent (3070%) complications in patients undergoing hemopoietic stem cells transplantation (hsct) for hematological malignancies . Musculoskeletal and skin cgvhd, by inducing fibrotic changes in tissues, may result in reduction of joints range ...
Advances in minimally invasive technology and surgical techniques have allowed more complex procedures to be performed including laparoscopic anti - reflux surgery, laparoscopic myotomy for achalasia, laparoscopic and thoracoscopic staging for esophageal cancer, videoassisted thoracoscopic (vats) lobectomy, vats belsey...
Type 2 diabetes or hyperglycemia, which is characterized by high blood glucose levels and glycosuria, is an endocrine disorder . It may occur for two main reasons: (1) deficient / insufficient secretion of insulin by the pancreatic beta cells; or (2) decreased or lost sensitivity of the insulin receptors . These two fa...
In many research institutions, we often do not appropriately support effective and dynamic undergraduate science education . Educators are held in high esteem as the agents of change for our youth, but they are unfortunately resistant to changing their teaching styles and practices (handelsman et al ., 2004). Over the ...
Hepatocellular carcinoma (hcc) is the third leading cause of cancer mortality worldwide with five - year relative survival rates less than 15% . Most of the risk factors for hcc, including chronic infection with hepatitis b virus (hbv) or hepatitis c virus (hcv), lead to the development of liver cirrhosis, which is pre...
The unroofed coronary sinus (cs) syndrome is a rare entity (1 - 5). Approximately, 75% of cases with the unroofed cs syndrome are associated with a persistent left superior vena cava (svc) (1). There is no reported case of an unroofed cs syndrome accompanied by the cs stenosis in the english literature . The clinical p...
We studied serum samples from 376 canadian patients with community - acquired pneumonia (121 ambulatory and 255 hospitalized) and from 511 healthy control subjects . All of these samples were previously tested for other pneumonia agents (4). To prepare antigen for microimmunofluorescence study, mimivirus was grown in a...
One of the key tools for the operating surgeon is the sense of touch . Through that, the surgeon is often able to determine inflammation and induration, create dissection planes, and identify vascular structures . The circumstances are wide ranging from the assessment of bowel viability in preparation for a bowel resec...
Adaptive immunity is based on the recognition of specific molecular structures, named epitopes, by either antibodies / b cell receptors or t cell receptors . Antibodies and b cell receptors bind a wide variety of structures, including proteins and carbohydrates . In the case of protein ligands, antibodies can recognize...
Shock wave lithotripsy (swl) was invented in the early 1980s and since then has become a standard treatment for renal and ureteral calculi owing to its noninvasiveness . Swl is particularly recommended for the treatment of renal and ureteral stones smaller than 10 mm . Swl has been less successful in treating larger ur...
There is a period in brain development in which the euthyroid status is a prerequisite for normal development . The molecular basis of the thyroid dependent brain development is not yet clarified . Among other processes, defects in myelination, delays in the development of the dendritic tree, decreased number of glial ...
Retinoic acids, including vitamin a and its analogues, regulate the growth and differentiation . Retinoic acids suppress tumor formation in animals and have shown to be effective chemotherapeutic agents in many cancers . Predominantly all - trans retinoic acid (atra) and its stereoisomer 9-cis retinoic acid were found ...
Obesity - induced inflammation is considered to be a potential cause of metabolic disorders such as insulin resistance, type 2 diabetes, and cardiovascular diseases [13]. Adipose tissue actively participates in obesity - induced inflammation through recruitment of macrophages and t cells and release of inflammatory cyt...
Since the introduction of the implantable cardioverter defibrillators (icd) in 1980, they have been instrumental in the health and safety of patients who are at increased risk of sudden death by ventricular tachycardia or fibrillation [1, 2]. The purpose of an icd is to prevent such events from occurring by sensing the...
A 5-year - old male patient of 111 cm and 19 kg, who experienced an osteosarcoma in the left fibula was to go undergo insertion of a totally implantable central venous access device for chemotherapy . Hence, the patient was admitted for surgery for the removal of the infected catheter and for left totally implantable s...
One of the fundamental aims of surgery is to return postoperative patients to their home environment in a safe, timely fashion . Day surgery is the admission of select patients to hospital for a planned surgical procedure after which they return home the same day . The economic slowdown has had a major affect on health...
Behavioral experiments show that elasmobranch fishes (sharks, skates, and rays) can detect changes in the geomagnetic field [13], and studies of migration [4, 5] give strong evidence that several species can navigate over long distances in environments where the geomagnetic field is the only plausible reference . Both ...
Heart failure (hf), a terminal stage of multiple heart diseases, is a leading cause of death all over the world . It is estimated that hf contributed to 1 out of 9 deaths in the united states during 2009, and approximately 284 000 people died of hf in united states in 2013 . It is estimated that chronic heart failure (...
Over the past 10 years or so, numerous molecules that can promote and/or inhibit axonal growth have been identified, and an emerging theme is that these molecules function by activating a limited number of signal transduction cascades in growth cones (tessier - lavigne and goodman, 1996; doherty et al ., 2000). Ncam, n...
The coefficient of linear thermal expansion (cte), thermal conductivity and the nature and strength of the bond are all factors that influence the porcelain's capacity to resist fracture during clinical use of the restoration11,21 . In agreement with many authors, the difference in ctes of porcelain and metal has been ...
Fahr's disease is a rare disorder that was first described by karl theodor fahr in 1930 . It usually presents with either slow progressive cognitive decline, psychiatric disturbance, or movement disorders . We describe a patient with an acute deterioration in the level of consciousness and a ct scan demonstrating both ...
There is a common and diffuse false myth that aging is synonym of deterioration, pathology, and death . The increased life expectancy in developed and developing countries is parallel to the need to identify interventions able to preserve health and function even at older age, delaying the physical and cognitive declin...
Gaining invasiveness and overcoming the physical barriers imposed by the extracellular matrix (ecm) are the first, and arguably most critical, steps of tumor metastasis . In addition to facilitating dissemination, remodeling of the ecm invadopodia of malignant cancer cells are actin - rich, ecm - degrading membrane pro...
The decade of the eighties produced a number of significant changes in the medicaid program . Increased numbers of recipients, rising costs, and many other health care issues have had a major impact on the program . As a result, an awareness has grown that increased control over the direction of the program is necessar...
India is currently undergoing a demographic transition, with a shift to a higher proportion of elderly (increased from 5.6% in 1961 to 7.4% in 2001). (1) increasing numbers of people are at risk of age - related visual impairment as the elderly population increases. (2) blindness and hearing impairment contribute heavi...
Gelastic seizures (gs) are an uncommon seizure type; they are characterized by sudden inappropriate attacks of uncontrolled and unmotivated laugh . One century later, the term gelastic epilepsy (from gelos: joy), was suggested by daly and mulder to define epileptic fits where laughter is the only or predominant symptom...
During november 2012june 2014, a total of 177 international travelers returning to ontario were considered persons under investigation (puis) for mers - cov, according to the guidelines of the ontario ministry of health and long - term care (6). Puis were recommended to be isolated and screened for mers - cov and other...
Nationwide surveillance of mrsa in finland, including notification for human cases and isolate characterization, was started in 1995 (6). From 1995 through april 2009, a total of 10,615 nonduplicate human isolates of mrsa were typed by using pulsed - field gel electrophoresis (pfge); 1 in 2007, 6 in 2008, and 3 in 2009...
Anemia accompanies a variety of chronic illnesses including inflammatory disorders, neoplasia, and infection . In some infection diseases such as mycoplasma pneumoniae, correlative clinical reports, supported by in - vitro studies, suggest a significant role for the inflammatory cytokines interferon gamma (ifn) and tum...
Cloacal and tracheal swab samples and serum were collected from 60 of 500 chickens on the patient s family farm and from 50 chickens in the backyards of 5 neighbors within 3 kilometers . In addition, 36 fecal samples from chickens on the patient s and neighboring farms were also collected . Each swab or fecal sample wa...
In the big data era there is an increasing use of large healthcare administrative databases to conduct clinical and healthcare research, besides learning assessing delivery efficiency and effectiveness . Among many interesting healthcare research topics facilitated by big data another interesting topic is use of multip...
The emphasis is now student - centered rather than teacher oriented and content - centered . This change in focus has necessitated other changes in curriculum design and delivery to meet this shift . Engagement of students in the learning process is, perhaps, the most important manifestation of the recent educational r...
Patients with systemic rheumatic diseases, particularly rheumatoid arthritis (ra), systemic lupus erythematosus, systemic sclerosis, and idiopathic inflammatory myopathies, are at increased risk of developing malignancies . This risk is related to the pathobiology of the underlying rheumatic diseases including the infl...
The interplay between gut microbiota and the immune system is a complex balance to maintain health and immunity, notably in chronic inflammatory diseases . Here, we review the changes in gut microbiota during hiv infection and the factors which modulate gut microbiota in relation to inflammation in hiv patients . We al...
We used m. tuberculosis cdc1551, a clinical isolate, as the host strain to generate a transposon insertion mutant in mt2594 (ldtmt2::tn) as described 14 . This mutant carries a himar1 transposon insertion at + 872 base from the putative translation start site of the gene . This is a single copy integrating plasmid base...
Multiple sclerosis (ms) as one of the most frequent diseases of the central nervous system (cns) in young adults often entails persistent physical and mental disability . The prevalence is assumed to be 400,000 people in the united states and approximately 2,1 million people worldwide . Mostly, ms begins with a relapsi...
Morbihan syndrome is a rare entity characterized clinically by chronic erythematous edema localized exclusively on the forehead, glabella, eyelids, and cheeks . Oral isotretinoin is considered the therapy of first choice, although not all patients improve . A 60-year - old caucasian man was admitted to our department b...
Hereditary spastic paraplegia (hsp) is a clinically and genetically heterogeneous group of neurodegenerative diseases that predominantly involves the lower extremities . The essential features are insidiously progressive spastic leg weakness associated with corticospinal tract and dorsal column degeneration . Hsp is cl...
The bacteriophage p1 cre recombinase, a 38-kda protein, recognizes specific 34-bp sequences called loxp sites and catalyzes site - specific recombination between two loxp sites [1, 2]. The cre - loxp system has been considered an important tool for manipulation of genomic sequences and gene expression including tissue ...
Somalia, the easternmost nation in the horn of africa,1 is classified as a fragile state . The recurrent civil conflict for over 20 years has impeded progress toward improving health care in somalia.2 its capital mogadishu has been a haven for armed gangs, islamic militants, and pirates, and for more than two decades, ...
Mitochondrial cytopathies (mc) are a rare and complex group of neuromuscular diseases due to a defect in the oxidative phosphorylation (oxphos) system . Symptomatic renal involvement in mc has been documented in the form of tubular defects (complete de toni - debr - fanconi syndrome in severe cases to incomplete proxim...
Acute upper gastrointestinal bleeding (ugib) is a common and potentially life - threatening emergency facing clinicians with an overall annual incidence of approximately 100 hospital admissions per 100,000 population . Peptic ulcer bleeding is a common medical emergency accounting for 50%70% of cases of acute nonvarice...
The who estimates that there are over 1.5 million blind children in the world, of whom nearly 90% live in the developing nations (who factsheet 282, 2011 and). Poverty greatly compromises the children's quality of life; childhood mortality rates are greatly elevated (sightsavers estimates that fewer than 50% of blind c...
Atherosclerosis or arteriosclerotic vascular disease is caused by deposited fat in blood vessels such as cholesterol and other types of plasma fat . When there is a high deposit of fat in blood vessels, the risk of atherosclerosis also increases, which has a direct connection with age, gender, exercising or not exercis...
Glyphosate is a non - selective herbicide, widely used in agriculture, forestry, industrial weed control and aquatic environments . Proposed mechanisms of glyphosate surfactant herbicide (glysh) toxicity to mammals include uncoupling of oxidative phosphorylation and glyphosate - or polyethoxethyleneamine (poea)-mediate...
Hyperparathyroidism (hpt) is one of the most important causes of calcium and phosphate metabolic disorders . It is a condition that occurs due to an increased activity of the parathyroid gland arising from either an intrinsic or extrinsic cause . An intrinsic change in the parathyroid gland culminating in the overprodu...
In meiosis, reciprocal recombination, also known as crossing over or chiasma formation, plays the vital role of holding homologous chromosomes together until their proper segregation at the first meiotic division . In human females it has long been known that either the failure of a pair of homologs to recombine, or an...
Mastitis is inflammation of mammary gland affecting all the species of domestic animals and is of great concern to dairy industry . Bovine mastitis can be classified into two types, namely, clinical mastitis and scm . Clinical mastitis is detected by the changes in physical appearance of milk, swelling, redness, and ri...
Gastroesophageal reflux disease (gerd) is characterized by recurrent regurgitation into the esophagus, causing heartburn, chest pain, and dysphagia . Gerd is a highly prevalent (1020% of the population) condition having a significant impact on the quality of life leading to high healthcare expenditures . Gerd patients ...
Osteoarthritis (oa) is a slowly progressive degenerative disease characterized by escalated loss of articular cartilage . It is one of the most common causes of pain and disability in middle - aged and older people . The major pathological changes during the progression of oa are articular cartilage breakdown, osteophy...
About 382 million people in the world have diabetes, and this number is expected to rise to 592 million by 2035 . The prevalence of diagnosed diabetes in korea has increased from 2% in the 1970s to 9.8% in 2011, and in 2012 the rate for patients with poor glycemic control was reportedly as high as 71.5% . These finding...
To report a case of bilateral acute angle - closure glaucoma after oral administration of cabergoline for the treatment of galactorrhea . A diagnosis of secondary drug - induced angle - closure glaucoma was made in a patient with elevated intraocular pressure (iop) and myopic refractive shift, which was confirmed by ul...
The common malignancies in this age group involve the breast, cervix, blood and brain . The long - term survival of all cancer patients has improved with the therapeutic advances in the oncology . Many of these patients will eventually show interest in childbearing, putting the burden of fertility preservation on the m...
Compounds containing boron groups have attracted considerable interest recently owing to their extensive use as synthons in organic synthesis, particularly in suzuki cross coupling reactions . Organoboronic acids [rb(oh)2] and boronate esters [rb(or)2] are exceptionally attractive for these carbon - carbon bond forming...
The incidence of differentiated thyroid cancers (dtcs), including papillary thyroid cancer (ptc) and follicular thyroid cancer variants, is rising significantly globally over the past decades, with a wide geographic variation.1 in saudi arabia, dtc is the second - most common malignancy, accounting for more than 10% of...
Adnexa refer to the anatomical area adjacent to the uterus, and contains the fallopian tube, ovary, and associated vessels, ligaments, and connective tissue . The reported incidence of adnexal masses in pregnancy ranges from 1 in 81 to 1 in 8000 pregnancies . These cysts may be asymptomatic and may be coincidently foun...
A cross - sectional design was employed . For this study 73 patients with diagnosis of schizophrenia patients were required to be aged between 20 - 60 years, of either gender with diagnosis of schizophrenia (as per mini). Patients with comorbid axis - i psychiatric disorders (except nicotine dependence), personality di...
It includes behaviors such as slapping, hitting, rape, recklessness, driving and shooting in school, truancy, road rage and other high - risk behaviors . Nearly 18.6% of females aged 12 - 17 got into a serious fight at school or work . 14.1% participated in a group - against - group fight and 5.7% attacked another pers...
A major goal of genomic studies is to understand the regulatory architecture of the genome; how, for example, powerful regulatory elements, such as enhancers and silencers, which have the ability to act over large genomic distances, are constrained to act only on appropriate transcription units . There is considerable ...
Influenza throat swab specimens were collected in accordance with the case criteria outlined in canas et al . The criteria included patients with a fever> 37.8c accompanied by cough or sore throat . Throat swabs were taken within 72 hours of the onset of symptoms, placed in viral transport media (microtest, m4) (vtm), ...
Sudden changes in coronary plaque luminal surface morphology consisting of plaque rupture or fissure have been recognized as important mechanisms of acute coronary syndrome (acs). Plaque disruption is a reflection of enhanced inflammatory activity within the plaque, and the risk of plaque rupture has been shown to be a...
All species have to perform a balancing act with their genome: cram it into the cell (in the case of eukaryotes, a small part of that cell: for example, about 2 m of human dna in a nucleus of about 5 m diameter) yet make the appropriate regions readily available for replication and expression (and repair if something g...
Members of the kinesin-5 family are homo - tetramers with two motor domains at each end of a central four - stranded stalk . Kinesin-5 motors play a crucial role in cell division (kashina et al . 1996; sawin et al . 1992). We have recently shown that eg5 drives relative sliding of two microtubules, suggesting that each...
Anemia is widely prevalent in developing countries like india and the most common affected group is pregnant women with an estimate of nearly two - thirds of all pregnant women . The main cause of anemia in pregnancy is found out to be iron deficiency, i.e. About 95% . Because of that, iron deficiency anemia remains a ...
Congenital coronary arteriovenous fistulas are rare anomalies.1)2) however, patients may sometimes present the disease with bacterial endocarditis.3) we report a patient with congenital coronary arteriovenous fistula along with bacterial endocarditis of the mitral valve and embolism in the spleen and kidney . A 27-year...
The heptavalent pneumococcal conjugate vaccine (pcv7) schedule in the pediatric population has significantly reduced the incidence of pneumococcal diseases in both vaccinated children and unvaccinated individuals of all ages . This led to the conclusion that pcv7 not only was highly effective in vaccinated children but...
The advanced glycation endproduct (age) n - carboxy - methyllysine (cml), as recently investigated by kneyber and colleagues, can be formed either from glucose via ketoamine or glyoxal or from lipids by oxidation via glyoxal . This may explain why the pathophysiological role of ages is not restricted to diabetes, in wh...
Emergence of resistant strains and human immunodeficiency virus infection has made the situation even more complicated . In addition to above, paradoxical reactions to anti - tuberculous therapy have created difficulties in the diagnosis and management of extrapulmonary tuberculosis, particularly central nervous system...
Septoplasty in adults is a well - established surgery, but in children it is still a matter of controversy . Some authors contraindicate surgery before 17 to 18 years of age, because they think that early surgical intervention would influence the normal growth of the nose; others indicate surgery based on the explanati...
This study was approved by the sheba medical center and maccabi healthcare services (mhs) institutional review board committees . This study consists of elderly (65 years of age) type 2 diabetic subjects who are engaged in the idcd, a longitudinal investigation assessing the relationship of long - term type 2 diabetes ...
A 40-year - old multiparous woman (164 cm, 74 kg) at 38 weeks gestation was admitted for a repeat cesarean section . She had experienced dyspnea on exertion for 10 years, and ild had been diagnosed with a lung biopsy one year previously . The pulse oximetry (spo2) was 95% with the patient breathing room air in the ante...
Gastroenterologists and surgeons who specialize in the treatment of crohn disease (cd) and chronic ulcerative colitis (cuc) have become increasingly aware of the implications of different forms of medical therapy on surgical outcomes . This is especially important in the era of top - down and multi - agent therapy for ...
Evidence has been accumulated over the last decades supporting the idea that reactive oxygen species (ros) play a principal role in pathogen elimination by the microbicidal activity of phagocytes . Ros have also been described to induce modifications of nucleic acids, proteins, and lipids, resulting in a crucial effect...
The generation of global enh, global cypher, cyphers, and cypherl knockout mouse models has been described previously.14,21,22 genotyping of isolated embryos, neonates, and mice was performed using previously described primer sets.14,21,22 all experiments described in this study were completed using mice of a mixed 129...
Porcine reproductive and respiratory syndrome (prrs) was first described in 1987 in united states and subsequently discovered in 1990 in europe . Despite ofchronicle proximity of the discovery, presumably derived from common ancestor and structural similarity of the viruses, these isolates from two different continents...
Arsenic compounds are ubiquitous in nature and are released into the environment via industrial or agricultural processes as well as some medical applications . Consumption of arsenicals such as sodium arsenite through contaminated water is prevalent in many areas of the world . Sodium arsenite is a clastogen causing c...