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Vaginal prolapse surgery is intended to restore normal pelvic floor function by correcting anatomical abnormalities . One of the most common complications directly related to prolapse surgery is the occurrence of incomplete emptying of the bladder . Whereas the optimal management is assessed in several studies, the und... |
Ischemic heart disease is a major cause of heart failure and mortality . According to the global atlas on cardiovascular disease prevention and control published by the world health organization in 2011, an estimated 17.3 million people died of cardiovascular diseases in 2008, representing 30% of all global deaths . Re... |
Acute low back pain is one of the most common conditions encountered in primary care . The lifetime prevalence of low back pain has been reported to be 7085% . In majority of the cases, acute back pain is self limited and benign with no cause identified in 95% of the patients . In such patients when acute back pain is ... |
To evaluate the effects of maxillary sinus floor elevation by a tissue - engineered bone complex of -tricalcium phosphate (-tcp) and autologous osteoblasts in dogs . 12 cases of maxillary sinus floor elevation surgery were made bilaterally in 6 animals and randomly repaired with the following 3 groups of materials: gro... |
Whipple operation or pancreaticoduodenectomy is a commonly performed curative surgery for pancreatic head and distal common bile duct cancers . While peri - operative mortality has improved over the past decades, the high peri - operative morbidity remains unchanged (1). Percutaneous image guided procedures plays an im... |
A woman's body undergoes various changes during pregnancy which include weight gain, changes in posture, and joint and ligament laxity along with changes in musculotendinous strength . Soon she realizes that her body is undergoing turmoil of events, and then the aches and the pains associated with pregnancy begin . Maj... |
The axons of many neurons migrate along both the dorsal - ventral and the anterior - posterior axes at different phases of development, and may also cross the midline . An individual axon may be subjected to opposing attractive and repulsive forces coming from opposite sides in the elongation axis or perpendicular to i... |
The human protein kinase c (pkc) family of serine / threonine kinases comprises nine distinct isotypes with essential roles in cellular activation and differentiation in diverse cell types . They are, for example, known to phosphorylate several cellular proteins, leading to modulation of surface antigens, activation of... |
A thorough knowledge of the root and the root canal morphology of all existing canals plays a significant role in determining the success of endodontic treatment . Successful treatment of endodontic complications is associated with diagnostic imaging techniques that provide information about the teeth and their surroun... |
The race for the first appendectomy in the 19th century did not produce a winner . From today's viewpoint, it can be assumed that lawson tait performed the first appendectomy via abdominal access in 1880 . Many of his surgical predecessors had merely performed drainage of a paratyphlitic abscess, without actually remov... |
Intensive care unit (icu) is a ward that caters to patients with acute and life - threatening diseases . The patients hospitalized in this ward experience numerous stressors due to environmental factors and specific treatment conditions or surgery . Physiological reactions excite the stress response and lead to an incr... |
A 34-day - old male infant with cyanosis and weighing 3,900 g was referred to kyungpook national university hospital for surgery . Oxygen saturation was below 80% and gradually decreased to 70% at the time of operation . Echocardiography indicated a complete transposition of the great arteries (tga) with a ventricular ... |
Diagnosis of hyperthyroidism which occurs in 0.05 to 3.0% of pregnancies may be difficult in these women, as the symptoms and signs of nervousness, sweating, dyspnea, tachycardia, and cardiac systolic murmur are seen in most normal pregnancies as well [1, 2]. More specific findings of hyperthyroidism such as weight los... |
Alzheimer's disease (ad) is a progressive neurodegenerative disorder that results in widespread brain atrophy of both gray and white matter brain regions . Other hallmarks of the disease include the extracellular deposition of amyloid- (a) and intracellular accumulation of hyper - phosphorylated tau . An emerging metho... |
Binocular rivalry (br) is the perceptual competition resulting when two different images are presented simultaneously to corresponding retinal locations (wheatstone, 1838). A race between the two monocular images leads to continuous perceptual alternations, with successive periods of dominance and suppression . The spo... |
In total, 140 suspected measles cases were reported to the taiwan centers for disease control from november 2008 to may 2009, and 53 were confirmed (table a1). The criteria for confirming cases included laboratory diagnosis and establishing an epidemiologic link to the laboratory - diagnosed case . The criteria for the... |
Taekwondo has grown as a global martial art sport, and is now being trained in 188 countries all over the world . In addition, the value of taekwondo competition as a sport has been so widely acknowledged as to be adopted as a formal event 4 consecutive times in the olympic games1 . Taekwondo as a martial art sport aim... |
The transient nature of the disabilities of mental illnesses and the nature of the socio - occupational impairment posed a challenge for the measurement of the disability . As this was the major hurdle in including mental illnesses into the government's social welfare benefits under the persons with disability act of 1... |
Compounds containing azomethine group (c = n) in the structure are known as schiff bases which are usually synthesized by the condensation of primary amines and active carbonyl groups . Schiff bases are found to exhibit multifunctional properties, and they are able to improve various biological and pharmacological acti... |
Pancreatic endocrine tumors (pets) are relatively rare, having a clinical detection rate of 1:100,000 which comprise 1%2% of all pancreatic tumors.1,2 pets are considered functional or nonfunctional and may be sporadic or inherited but little is known about their molecular pathogenesis.1,2,3 there is currently no forma... |
Generally, about one - third of patients undergoing radiotherapy (rt) have experienced rt - induced nausea and vomiting (rinv). In this regards, the radiation oncologists have attitude of prescribing antiemetic drugs as a rescue, with a wide range of doses and schedules . They also prescribe 5-hydroxytryptamine (5-ht3)... |
Radical prostatectomy has historically been the preferred treatment option for patients with localized prostate cancer . However, surgical innovations to reduce blood loss and hasten the recovery rate have led to the introduction of laparoscopic radical prostatectomy (lrp) followed by robot - assisted radical prostatec... |
Due to current serious exiting challenges in conventional transistor technology, researchers are searching to find an alternative to this technology . Among these new technologies, quantum - dot cellular automata (qca) are a suitable alternative that offers unique features such as small feature size and ultralow power ... |
Testosterone is responsible for secondary sex characteristics, sexual desire and erection . Also, it increases metabolic processes in the muscles, bones, bone marrow, immune system and brain (1). Therefore, a reduction in the level of testosterone leads to symptoms that are caused by the decrease of these processes . T... |
Although the pathogenesis of alzheimer's disease, including the pathophysiology leading to excessive a 42 deposition in ad brain, remains unknown, it is characterized by the excessive accumulation of beta - amyloid peptides in varying size aggregates, predominantly within neocortex [13]. This study looks at one of the ... |
Many countries around the world have been reducing the level of state provision of resources for retirement, moving towards a system that relies on an increased degree of individual or private provision . The uk has been at the leading edge of these changes, particularly for pensions . As private saving has become incr... |
It has been well documented that exercise is an effective health behavior that not only prevents various health problems, but also promotes healthy lifestyles (1). In addition, in many areas, the physical and psychological benefits from regular physical activity in reduction of mortality and morbidity in both general a... |
An increasing number of studies are confirming an association between periodontal disease (pd) and adverse outcomes in pregnancy . Found that pregnant women with severe pd are 7.5 times more likely to go into labor prematurely . Pd places pregnant women at greater risk for preterm birth than alcohol consumption or smok... |
In the past, medical students have been involved in direct patient care in large - scale mass casualty incidents; from the spanish flu pandemic in 1918,1 flooding,2 devastating earthquakes3 4 to the 9/11 attacks,5 medical students have been deployed for the purpose of victim care . The belgian royal academy of medicine... |
Twelve mabs have already been approved by the us food and drug administration for therapeutical use and 400 others are currently under clinical evaluation . However, a number of hurdles have still to be overcome before efficient therapeutical application of mabs on large scales and at reasonable costs . This is particu... |
Systemic lupus erythematosus (sle) is a life - threatening illness which may lead to chronic disease affecting multiple organs . Induction of rapid and sustained remission is the optimal treatment result . In recent decades, multiple immunosuppressive drugs, such as cyclophosphamide, azathioprine, cyclosporine, or myco... |
Unconscious survivors of ventricular fibrillation cardiac arrest in intensive care units (icus) are increasing . Usually, patients who awaken do so within 48 h of stopping sedation; patients unconscious at day 7 remain severely impaired . Specifically, the significance of myoclonus continues to be debated, especially f... |
Sporadic hemiplegic migraine is a rare subtype of migraine headache with aura defined as migraine attacks associated with some degree of motor weakness / hemiparesis during the aura phase and where no first- or second - degree relative (parent, sibling or child) has identical attacks . The earliest description of this ... |
Environmental control practices (ecps) are a group of measures recommended to reduce exposure to indoor allergens (eg, dust mites, household pets, cockroaches, mold, mice) or nonallergic triggers (eg, environmental tobacco smoke [ets], wood smoke, volatile organic compounds, particulate matter [pm]). Historically, many... |
These examples show that the relationship between labour economics and healthcare professional education is complex and dynamic and that well - meaning changes in one part of the system can produce unintended and unexpected changes in other parts . Simple solutions to individual problems are thus unlikely to work and i... |
Over recent decades, there has been an accrual of evidence concerning the beneficial effects of social relationships on physical and mental health in older people, including longer survival, reduced risk of disability [2, 3], and reduced risk of dementia . Cross - sectional and longitudinal studies [611] have generally... |
Differences in gene expression account for the majority of phenotypic differences between males and females of sexually dimorphic species 1 . Thus, accurate identification of genes differentially expressed between males and females, i.e. Sex - biased genes, is crucial for understanding the current state and evolution o... |
Whole blood viscosity (wbv) is one of virchow's triad, which has been an established concept of three phenomena that ultimately lead to, and/or result from cardiovascular complications . Each phenomenon represents a subclinical vascular process, which in turn is indicated by a pathology index and clinical features . Sp... |
Keeping in mind the burden of psychotherapy can play a crucial role concerning chronic pain (cp). Psychological methods have provided a lot of articles in iran, but they were neglected by the reviewers because the documents only have abstracts in english . The current study aimed to assess all farsi randomized control ... |
Granuloma faciale (gf) is an uncommon benign inflammatory condition of the skin with characteristic clinical and histological features . Pinkus originally described the name in 1952, although there had been earlier reports of eosinophilic granulomas . It mostly affects the face, particularly sun - exposed areas such as... |
Epithelial ovarian cancer (eoc) has the highest death rate among gynecologic malignancies throughout the world, primarily because most patients are diagnosed with advanced stage disease . The standard treatment consists of cytoreductive surgery followed by induction chemotherapy with a taxane / platinum combination . D... |
The transition period, from 3 wk before to 3 wk after parturition, is critically important to health, production, and profitability of dairy cows . There are lots of serious changes for dairy cows in transition period from the end of pregnancy up to the beginning of lactation period . This period was really important f... |
Leadership concept goes back to 5000 years ago to egyptian hieroglyphics in which the words (sehemu) leader and (seshement) leadership are used .this was the assumption behind the great man theory. The human relations approach to leadership, which was developed after mayo s studies, views leadership as an interactional... |
An extensive buildup of military personnel and operations has begun on the mariana islands of guam and tinian . We recently communicated that this situation presents an exemplary ecological ethics case study with provocative history and compelling contemporary events . We detailed failures in adhering to respectful env... |
The tightness of the hip flexor muscles limits hip hyperextension in gait and may correlate with lumbar curvature, back pain, and knee dysfunction . The modified thomas test is used to assess the flexibility of four different types of hip flexor muscle: the iliacus, psoas major, rectus femoris, and tensor fasciae latae... |
As thyroid hormones play a critical role for metabolism, growth, and tissue differentiation, exact and robust regulation of hormone levels is required . Although a thyrotropic hormone from anterior pituitary has first been described at the beginning of the 20th century [1, 2], it was not before 1940 that salter postula... |
We report the case of a healthy 32-year - old female colleague, who was admitted to our hospital in septic shock with high fever (40c), tachycardia and hypotension, with no response to fluid resuscitation and antibiotic therapy . Her symptoms started 4 days before with isolated sore throat (no rhinitis or cough) follow... |
The ministry of health and medical education of iran, along with the country movement towards achievements of iran s vision 2025 put compilation of the health system reform plan on its agenda . In this article, we are trying to show the method we used for developing this plan and how this method considered the general ... |
Study area and population - juquitiba is located 71 km from the capital of sp (fig . 1) in the atlantic forest biome, at an altitude of 685 m. approximately 67% of its length is covered by bushland and the preserved native forest promotes great movement of individuals due to ecotourism . Juquitiba has a population of 2... |
Exclusive breastfeeding during the first six months of life is vital to the short and long - term health of the baby . Breastfeeding is also beneficial for maternal health [2, 3] and is financially sustainable for the health system [46]. In 1991, the who / unicef launched the bfhi to promote exclusive breastfeeding in ... |
Cancer is the third most frequent cause of death in children in brazil, after accidents and violence (1). The survival rates of childhood cancer have significantly increased due to early diagnosis and advances in medicine, so attention has become focused on the late effects of antineoplastic therapy . Dental anomalies ... |
Skeletal muscle dihydropyridine (dhp) receptors are l - type ca channels that serve a dual role in muscle, functioning both as ca - conducting pores and as the voltage sensors for excitation contraction (e - c) coupling (ros and brum 1987; tanabe et al . These channels are heteromeric complexes containing the pore - fo... |
Viral integration into host chromosomes plays a key role in viral infection (1,2) and tumorigenesis (38). The role of oncogenic viruses in cancer pathogenesis is mediated through mutagenic integration into the host genome as one of important mechanisms (2). Viral integration sites (vis) have been observed adjacent to o... |
The four experiments presented here can be performed independently or as a four - part series . Experiment 1 introduces students to the concept of model prebiotic chemical reactions, experiment 2 teaches the students how to isolate dna from a living organism, experiment 3 teaches the students how to release purine base... |
Soft tissue calcification is one of the major clinical findings of chronic kidney disease - related mineral bone disorder (ckd - mbd), along with abnormalities in laboratory examinations and bone metabolic disorder . However, soft tissue calcification in ckd - mbd appears to be a heterogeneous disease condition . Some ... |
The premises used for different functions of the same process can be scattered around the hospital, a far cry from seamless patient care . Planning a new hospital functional planning should guide the design of a new hospital and aim to create facilities that support efficient, streamlined, and patient - centered health... |
It is characterized by a lack of gross patency of the extra hepatic bile duct of which there are three main types . Type i atresia of the common bile duct; type ii with additional atresia of the common hepatic duct but residual patency of the right and left ducts; and type iii with atresia of the whole of the extrahepa... |
Hyperlipidemia is characterized by elevated levels of plasma total cholesterol (tc), triglycerides (tg), and low - density lipoprotein cholesterol (ldlc) [1, 2]. Patients with hyperlipidemia are considered to be at high risk to develop lipids disorders that are associated with immune system deficiency, promoting manife... |
The ability of cells to adhere to one another is a fundamental property in the evolution of multicellularity . Cell adhesion molecules conserved among metazoan organisms, which play essential roles in tissue morphogenesis and homeostasis [15]. During morphogenesis, tissues can change in size and shape, and form distinc... |
The basal ganglia receives inputs from wide areas of the cerebral cortex, in particular, from the frontal lobe . The information processed in the basal ganglia is transmitted back primarily to the cerebral cortex, via the thalamus, to form a cortico - basal ganglia loop.1,2 in this circuitry of the basal ganglia, the s... |
Children have the highest attack rates of influenza and an increased risk of influenza - related hospitalizations due to their naive immune systems . Putting aside the matter of community transmission and herd effects conveyed to the entire population that are achievable by vaccination of children, direct protection of... |
Primary hyperparathyroidism is a common endocrine disease that affects 1% of the adult population1; its incidence is increasing, and surgical treatment remains the only curative therapy.2,3 primary hyperparathyroidism is commonly due to a single parathyroid adenoma (80%87%) followed by multigland disease (5%15% with as... |
Autism spectrum disorder (asd) is a complex developmental disorder characterized by abnormalities of verbal and nonverbal communication, stereotyped restricted interests, repetitive behavioral patterns, and impairment of socialization . Asd now affects 1 in 88 children in the usa [1, 2]. In great britain, the costs of ... |
Parkinson s disease fibroblasts were obtained from telethon genetic biobank network and brain patient samples from the biobank of hospital clinic (idibaps) in barcelona . The generated ipsc lines were maintained in hesc medium on imef feeder cells or in mtesr on matrigel . Gene targeting in ipscs - lrrk2(g2019s) and h9... |
Nowadays, the importance of nurses tasks and responsibilities in performing nursing cares attracted a lot of attention . It is necessary for nurses to make an evolution in their traditional roles to accommodate with the needs of the modern society (1). Nursing education should prepare its students to enable them perfor... |
Inguinal hernia is a common neonatal disease, particularly in premature and low - birth - weight infants . Multiple studies have reported postoperative apnea with routine doses of anesthetics and its association with gestational age less than 37 weeks or post conceptional age (pca) under 60 weeks at the time of operati... |
Bladder cancer is the second most common urologic malignancy; with a high incidence in the elderly patients . The population has aged progressively as the average life span has increased in the last decades . Therefore, is highly important to solve the issues of managing bladder cancer in the elderly patient . Radical ... |
Numerous studies have shown that hemofiltration using porous synthetic membranes can and does remove a wide range of substances that mediate inflammation from the plasma . Limited evidence supports the notion that this treatment can also influence circulating plasma concentrations of various mediators and mounting evid... |
The 1965 medicare legislation was intended to reduce financial barriers to hospital and physicians' services for the elderly population in the united states . The implementation of the medicare program meant that virtually the entire population 65 years of age or over became covered for medicare part a hospital service... |
Chronic hepatitis c virus (hcv) infection affects about 3% of human population worldwide and has become an important leading factor to liver fibrosis, liver cirrhosis, and hepatocellular carcinoma (hcc) (1). About 30% to 40% of patients with chronic hepatitis c (chc) develop iron overload (2 - 5), which increases both ... |
Among the most important protozoan parasitic species causing diseases in humans, five had their genomes recently sequenced . Three of them are pathogenic members of the order kinetoplastida, family trypanosomatidae, that cause sleeping sickness (caused by pathogenic subspecies of trypanosoma brucei), chagas disease (t.... |
Lumbar spinal stenosis complicating degenerative spondylolisthesis is a common cause for low back pain, neurogenic claudication, and radiculopathy in the elderly population . However, in patients that fail to respond to conservative treatment, surgical decompression with or without a posterolateral fusion and instrumen... |
Dynamic balance can be defined dynamically as the ability to perform a task while maintaining a stable posture . The influence factors of dynamic balance include sensory information obtained through the somatosensory, visual, and vestibular systems and motor responses that affect coordination joint range of motion (rom... |
A rash developed in the index case - patient (an unvaccinated woman) on february 23, 2014, nine days after she disembarked the cruise ship on which she had traveled during february 614, and returned to sardinia . While infectious, she was seen in the emergency department (ed) of a local hospital, where she was admitted... |
Primary extrauterine choriocarcinoma is very uncommon disease, that usually arises from retroperitoneum, mediastinum and it rarely occurs at any site (eg, intracranium, stomach, bladder, lung), especially primary lung choriocarcinoma is very rare disease . We report a case of primary lung choriocarcinoma which is confi... |
The brazilian form, known as fogo selvagem (fs), predominantly affects young people; both sexes are equally affected . In this disorder, many cases present a genotype clustered within families; and autoantibodies are found not only in patients, but also often in relatives of the patients[14]. The autoantibodies are les... |
Viral infection - associated acute encephalopathy / encephalitis is a serious complication with neurological sequelae . The main symptoms of the acute phase are impaired consciousness and convulsive status epilepticus with hyperpyrexia . Several subtypes of acute encephalopathy have been established based on clinical, ... |
Anaplastic large cell lymphoma (alcl) is an uncommon non - hodgkin lymphoma with both systemic and cutaneous forms . Primary cutaneous anaplastic cd 30 + large cell lymphoma is a rare anaplastic large t - cell cd 30 + lymphoma originating in and confined to skin . There are case reports on primary cutaneous lymphoma on... |
Multiple myeloma (mm) and amyloid light (al) amyloidosis represent a malignant proliferation of plasma cells derived from a single clone . Myeloma kidney is predominantly contributed by the cast nephropathy, and patients with this kind of involvement suffer from renal insufficiency . The extent of proteinuria can vary ... |
Bite force is the result of the coordination between different components of the masticatory system (muscles, bones and teeth). Its determination has been considered important in the diagnosis of disturbances of the stomatognathic system1 . According to hatch, et al.2, in 2000, the bite force and the number of occludin... |
Deaths from postpartum hemorrhage (pph) occur as a result of a suboptimal clinical response to massive hemorrhage, whether due to limited or absent resources in developing countries or to poor coordination of resuscitative efforts in developed countries,1 and usually occur in the setting of coagulopathy . The most comm... |
The choroid is the middle vascular layer of the eye, lying between the retina and sclera . It accounts for 85 percent of ocular blood flow and plays a major role in the oxygenation, nourishment, and viability of retinal pigment epithelium and the outer retinal layers, which have the highest metabolic activity . Choroid... |
Phosphorylation of target proteins is a key mechanism utilized by the cell to induce changes in physiology and function . Numerous kinase - substrate interactions have been defined, yet the mechanism through which specificity of these phosphorylation events is achieved is still unclear . Recent work has suggested that ... |
Most current anti - cancer agents do not greatly differentiate between cancerous and normal cells, leading to systemic toxicity and adverse effects . With the aim of avoiding cancer therapy failure, several approaches such as design of new anti - cancer drugs, chemical engineering of conventional drugs and development ... |
Patient satisfaction is a widely used concept; today, it is considered one of the crucial dimensions of clinical governance (1). Satisfaction has a critical role in health maintenance and prevention of diseases (2) and is considered an indicator for evaluating organizational performance (3). Satisfaction is affected by... |
Although an inverse association between the two conditions has been suspected for a long time, no general relationship has been determined . Inflammatory reactions associated to allergy could favor neoplasia; on the other hand, enhanced immune - surveillance due to allergy could prevent neoplastic diseases (15). The st... |
Hydatid bone disease is often asymptomatic, and is therefore usually diagnosed at an advanced stage . We report an unusual case of a recurrent iliac hydatid cyst, despite surgical procedure which was performed in this case . She had previous medical history of iliac hydatid cyst in 6 years before (2006). At this time, ... |
Insufficiency fracture is occurred by repetitive normal stress without significant abnormal force in the area of elastic resistance deficiency . It is known to occur mainly in elderly female patients with osteoporosis . In particular, following hip or knee joint arthroplasty, it occurs very rarely . We describe one cas... |
The use of brain sonography or trans - fontanelle ultrasound scan (tfuss) in the diagnosis of childhood intracranial pathologies has been documented in the literature just like the use of subdural taps for the treatment of subdural empyema (sde). Subdural tap was used both for diagnosis and treatment of this condition ... |
In healthy individuals candida species are harmless members of the normal gastrointestinal (gi), oral, and vaginal microbial flora . It is assumed that everyone carries candida in their gi tract (reviewed in), with c. albicans the species most frequently identified in faecal sampling, representing 4070% of isolates [24... |
For this report, a malaria case - patient was defined as a person hospitalized with a diagnosis of malaria (code 084 in international classification of diseases, 9th revision, clinical modification) or reported as having a case of malaria through a military notifiable medical event reporting system . Persons could be c... |
A 35-year - old man presented with gradual diminution of vision in his right eye in october 2005 . His best corrected visual acuity (bcva) was 20/200 in the right eye and 20/20 in the left eye . On examination he was found to have cch in the macular area with serous retinal detachment involving the fovea, which was con... |
Fibrous dysplasia is a congenital developmental anomaly of bone which may occur in localised, regional or systemic forms . In this condition the normal bone is replaced by immature fibro cellular tissue, which may be considered to be a fertile soil for a plethora of lesions like aneurysmal bone cyst,[15] solitary bone ... |
Teratomas are congenital tumors containing all or either of the three germ layers and accordingly they are classified as monodermal, bidermal, or tridermal . Teratomas occur in order of decreasing frequency, in the ovaries, the testes, the anterior mediastinum, the retroperitoneal space, the pre - sacral and coccygeal ... |
Urinary incontinence is a chronic and costly to treat condition that is defined as a disorder that can be basically explained as inability to control urine or loss of bladder control . According to danford et al, there exist risk factors that cause increased chances of urinary incontinence, especially among women of ch... |
Which factors determine person s overall success in judo, and to what extent can these factors predict their future success? Answering this question is not simple, mainly due to the complexity of judo . Competitive success is determined by a number of features and capabilities, as well as technical and tactical perform... |
Most people suffered from acute or chronic lower back pain and experienced decreased mobility, stability, and muscle strength . The physician shall make the differential diagnosis for it such as vertebral fracture caused by osteoporosis, trauma, metastasis, and idiopathic factors . Fracture due to osteoporosis must con... |
Tuberous sclerosis is a genetic disorder, where cellular differentiation and proliferation result in hamartoma formation in the skin, brain, eye, kidney, and heart . The credit of its initial description, in the year 1862, goes to von recklinghausen, while dsir - magloire bourneville coined the term sclerose tubereuse;... |
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