text
stringlengths
0
868k
The capacity for appropriate, dynamic, and effective neuronal plasticity is essential for the normal development and function of mature neuronal networks . Neuronal plasticity can be defined as the ability of a neuron or network to functionally alter in response to changes in input or activity . These alterations can o...
Day 1 adult neuronally gfp - labeled worms (punc119::gfp or pmec-4::gfp) were prepared for cell isolation as previously described with modifications (extended data fig . The pellet (~250 l) was washed with 500 l lysis buffer (200 mm dtt, 0.25% sds, 20 mm hepes ph 8.0, 3% sucrose) and resuspended in 1000 l lysis buffer ...
Labor pain as one of the severest pains that has always been a concern to pregnant women and therefore relieving labor pain is an important part of modern obstetrics . Yet women's perception of labor pain depends on various factors including preceding labor pain experiences, mother's compatibility with pain, environmen...
The importance of symptom control in cancer populations, in particular, has been widely recognized due to the extraordinarily high prevalence of physical and psychological symptoms as well as the impact of these symptoms on patients' qol . For patients with advanced disease who have reduced life expectancy and no immed...
The eukaryotic rna exosome is a conserved ribonuclease complex that controls the quantity and quality of a large number of rnas . Exosome - mediated rna degradation leads to the elimination of nuclear and cytoplasmic transcripts in turnover and quality control pathways or to partial trimming of rna precursors in proces...
Aggregatibacter actinomycetemcomitans is a gram - negative, capnophilic coccobacillus, that is strongly associated with aggressive periodontitis (agp). Despite being considered a periodontopathogen, a. actinomycetemcomitans can frequently be detected in periodontally healthy individuals, suggesting variability in its v...
Epidermoid cyst of the breast is uncommon . It is commonly encountered over the face and back either by a dermatologist or general surgeon in day to day practice . A 48 years old male presented with swelling over the right side of breast that underlies nipple areola complex (nac) since last 6 years . Swelling was gradu...
Tricuspid regurgitation (tr) can be caused by pathologic involvement of the tricuspid valve but more often occurs in the structurally normal tricuspid leaflet and chordae which is called functional tr.1)2) functional tr can occur in several cardiovascular diseases such as left - sided heart disease, myocardial and pulm...
Depression is the third leading cause of burden of disease, and is an important public health issue since it is associated with suffering for the individual, disability, increased mortality, and poorer outcomes from physical illness.1 depression and depressive symptoms are also closely associated with decreased psychol...
Homeobox genes have crucial roles during embryogenesis and have been deeply studied from the point of view of the evolution of development . Changes in their number and regulation may have been instrumental in body - plan evolution and diversification . Whether the physical linkage of many homeobox genes is maintained ...
The treatment of choice for the partially edentulous patient, when all the factors are favorable, is normally a tooth supported fixed partial denture or implant supported the prosthesis . Some factors, however, militate against the use of tooth supported fixed partial denture and rule in favor of removable partial dent...
Despite having several potential complications, ventricular shunting for the treatment of hydrocephalus remains one of the most common neurosurgical procedures . The risk of shunt failure due to obstruction or disconnection is well characterized 1 . For ventriculoatrial (va) catheterization in particular, the incidence...
The risk of hiv transmission through orogenital intercourse (oi) has yet to be precisely quantified . Various case reports suggest that the risk of oi transmission is not nil but much lower than from vaginal and anal intercourse (ai). While some of these reports may have been misattributed to oi transmission through un...
Among various esthetic procedures for improving tooth colors, vital tooth bleaching is a well - accepted method of treating discolored tooth due to its conservative approach and higher cost - benefit ratio compared with other methods . Carbamide peroxide (cp: 3537%) or hydrogen peroxide (hp: 3040%) in high concentratio...
To report the experience gained over 4 years in working with the german sari project (surveillance of antimicrobial use and antimicrobial resistance in intensive care units), and to compare sari with data from the swedish strama and the us aur surveillance system . Prospective unit and laboratory based surveillance was...
Air pollution was not perceived as a major problem in most countries until late 1960s and early 1970s; it was the global cooling forecast that captured public imagination in urban and industrialized areas . In 2014, who released a report on air pollution, as the instigator of about 7 million people's death in 2012 . Th...
The bn nanotube (bnnt) and hexagonal bn (h - bn) are comprised of alternating b and n atoms in a honeycomb arrangement similar to carbon nanotubes (cnts) and graphene structures, respectively . Manifestation of a quantum - confinement effect in these low - dimensional structures provides them with superb material prope...
Tailgut cyst or retrorectal cyst hamartoma is a rare congenital lesion lying in the retrorectal or presacral space.1 2 it is thought to arise from the vestiges of an embryonic hindgut . The lesion is characterized by the presence of a cyst lined with multiple, various types of epithelia, with columnar mucin - secreting...
Advanced glycation end products (ages) are stable covalent, structurally diverse complexes that are formed when macromolecules, including proteins, lipids, and nucleic acids, undergo spontaneously non - enzymatic glycation with glucose and other reducing monosaccharides.1,2 ages formation is chemically irreversible, so...
Carcinoma of the oral cavity is rare and consists of 0.5% of the total amount of carcinoma s in the netherlands with approximately 520 new patients being diagnosed per year, . The most important risk factors are tobacco and (excessive) drinking, the simultaneous consumption of which is believed to have a multiplicative...
Breast cancer (bc) is the most common malignancy among women in most western countries.1 the development of bc involves a progression, starting with atypical hyperplasia, followed by intermediate stages until the invasive carcinoma, and finally into metastatic disease . A series of epigenetic and genetic changes contri...
All of the inhabitants (or their legal guardians) in both towns who provided blood samples and signed the written and informed consent were included in the study . Those who did not provide blood samples were excluded (n = 137, 25.6%). No statistically significant differences were found with respect to sex and age betw...
This article reviews the contributions of french schools to the development of psychiatric nosology . Briefly, french psychiatry enjoyed a pre - eminent position in the development of psychiatric nosology until the 1880s . From the 1880s until world war i, german - speaking schools exerted the most influence, with the ...
A cavernous malformation can be found in the cerebrum, the cerebellum, or the spinal cord . Lehner and colleagues (2006) have provided a recent literature review . To our knowledge, microsurgical extirpation of a recurrence of an intrachiasmatic cavernoma has not been reported previously . Her vision had decreased prog...
Most of the cases are asymptomatic with the exception of a few that may present with mild abdominal pain and nutritional deficiencies . Intestinal obstruction is an acute presentation that has been observed in a number of cases where there is an increased worm burden that may partially or completely block the intestina...
Human risk categories were created based on a typical contact type with wildlife: 1) casual (the general public), 2) recreational (waterfowl hunters), and 3) occupational (wildlife biologists, wildlife hospital workers, and veterinarians). Frequency of contact with aiv was estimated for each risk group by evaluating th...
Corneal astigmatism affects a significant proportion of patients undergoing cataract surgery; studies have estimated that 22% to 25% of cataract patients have more than 1.50 d of corneal astigmatism [1, 2]. Because residual postoperative refractive astigmatism compromises visual outcomes, concurrent reduction of astigm...
Dengue is amongst the most serious mosquito - borne infectious disease with hot spots in tropical and subtropical parts of the world . Unfortunately, no licensed vaccine for the disease is currently available in medicine markets (kovendan et al . The only option available is the management of the mosquito, aedes aegypt...
The requirement for informed consent was waived by the university of pennsylvania institutional review board and the gprd independent scientific advisory committee . The gprd contains data abstracted from a computerized medical record system used by a subset of general practices in the u.k . The information prospective...
The choice study is a national prospective cohort of incident dialysis patients (9). From october 1995 to june 1998, 1,041 participants (767 on hemodialysis) from 19 u.s . States were enrolled a median of 45 days after initiation of dialysis (95% within 3.5 months). Follow - up for all - cause mortality was available t...
Gabapentin is a widely used antiepileptic drug . As for the majority of these drugs, encephalopathy, manifested by transient somnolence, mood and motor disorders, however, to our knowledge, only two gabapentin - induced coma cases have been reported (buttler et al 2003; dogukan et al 2006). We report a third case of ga...
Anatomical fat patterning refers to the distribution or patterning of fat over the body . The importance of total body fat and distribution has been stressed as major risk factors such as hypertriglyceridemia, hypercholesterolemia, c - reactive protein, type 2 diabetes mellitus, elevated blood pressure, and endothelial...
Ever since the description of swenson's operation in 1948, its principle of completely resecting the aganglionic rectum and anastomosis of the ganglionic bowel to the anal canal still remains valid as the most physiological approach to hirschsprung's disease (hd). The essence of this operation lies in a precise pelvic ...
The spectrum of ap in pregnancy ranges from mild pancreatitis to serious pancreatitis associated with necrosis, abscesses, pseudocysts, and multiple organ dysfunction syndromes . Pregnancy related hematological and biochemical alterations influence the interpretation of diagnostic tests and assessment of severity of ap...
Attention deficit hyperactivity disorder (adhd) is the most common disorder in preschool and school - aged children . Although genetic factors account for 80% of the etiology of adhd, multiple pre-, peri-, and postnatal factors can result in adhd . Numerous experimental and clinical studies have correlated the sites of...
Spontaneous intracerebral hemorrhage (ich) is one of the most common emergency diseases in neurosurgery, with a prevalence of about 10 - 15% among cerebrovascular accidents, and is associated with high morbidity and mortality rates12368). Regarding treatment, surgery is considered in cases with large hematomas, lack of...
The antimalarial drug mefloquine (commonly marketed as lariam) had until recently enjoyed a long history of preferred use in certain military settings in the prophylaxis of chloroquine - resistant p. falciparum malaria . Originally developed by the us military in a vietnam war - era drug development program and subsequ...
Obviously, the behavioral reaction to the bang differs depending on the context, suggesting that information from the context (shelter versus beach) affects the interpretation of the explicit event (bang). Animal learning theory considers pseudoconditioning and higher - order conditioning to contextual cues as ways to ...
Quantitative prediction of binding affinities of ligands interacting with target macromolecules is one of the most important tasks for lead optimization and other procedures in computational medicinal chemistry . The majority of approved drugs and drug candidates contain tautomerism - prone heteroaromatic ring systems ...
It is well established that the proliferation of autoreactive t and b cells leads to cns inflammation and subsequent myelin destruction . Cd4 + t cells are believed to be the essential mediators of the inflammatory process in ms . However, the role of b cells, macrophages, and t cells other than cd4 + should not be neg...
Soon after this initial report, mckernan and saye and reddick and olsen performed the first laparoscopic cholecystectomies in the united states in 1988 . During the next ten years, laparoscopic cholecystectomy evolved into the accepted approach to manage symptomatic gallbladder disease . Multiple prospective randomized...
A direct carotid cavernous fistula (ccf) can result from trauma, rupture of a cavernous carotid aneurysm, or a tear in the wall of a cavernous internal carotid artery (ica) weakened by collagen vascular disease . Intracerebral hemorrhage from a direct ccf is very rare, occurring in only 0.9% of direct ccf cases accordi...
Betamethasone-17-valerate, betamethasone-21-valerate and betamethasone alcohol were kindly donated by gsk pakistan (pvt) ltd ., ar grade chemicals like disodium hydrogen phosphate, potassium chloride and citric acid were obtained from merck, germany . Formulation ingredients carbomer 940, cetostcaryl alcohol, hydroxyet...
Many previous clinical studies have suggested that atrial fibrillation (af) is associated with various risk factors such as cardiomyopathy, aging, diabetes mellitus, metabolic syndrome, hypertension, and obstructive sleep apnea [13]. In particular, hypertension is closely associated with the pathogenesis of af [48]. In...
These lens types selected are widely used across pacific asia . The five cos - cls we assessed were obtained arbitrarily without a prescription from the internet, a general pharmacy, or a mass merchandise outlet . The product names of the lenses and lens characteristics specified in the instructions or packaging are sh...
These include the stable association of proteins as part of a functional complex as well as the transient association proteins, such as a kinase with its substrates, leading to their phosphorylation . Disruption of these molecular interactions can lead to disease; therefore, understanding how proteins associate with on...
Alzheimer's disease (ad) is the most prevalent neurodegenerative condition in individuals over 65 . Ad neuropathology is characterized by progressive accumulation of amyloid beta peptide (brain amyloidosis), intraneuronal inclusion of hyperphosphorylated tau (neurofibrillary tangles), and degeneration of various neuron...
Since introduction of the activated sludge process in the early 1900s, many different types of subsurface or diffused aeration devices have been designed and developed to dissolve oxygen into wastewater . These have ranged from simple individual orifices (holes and slots) drilled in a section of pipe to elaborate devic...
Lung cancer is the leading cause of cancer death worldwide; its incidence and mortality rates have been increasing rapidly in the last three decades . Although lung cancer is largely caused by tobacco smoking, there is accumulating evidence for the role of genetic factors in the occurrence of the disease . Until now, s...
Schizophrenia is a serious illness associated with substantial loss of quality of life, social and economic problems, co - morbidity and premature mortality, and the need to improve primary prevention is paramount . Aetiology of schizophrenia offers few clearly modifiable factors: rates are higher in those with family ...
. The risk of fractures is greater among women with low bmd although it has now been accepted that differences in bmd and its changes explain only part of the increased fracture tendency among the elderly . Other parameters of bone quality may be more important measures of fragility [4, 5]. Overall, the individual frac...
Vitiligo, considered just a cosmetic problem, affects a person's emotional and psychological well - being, having major consequences on patient's life . Most of the patients of vitiligo report embarrassment and low self - esteem leading to emotional stress and social isolation, particularly if the disease develops on e...
Alkenes are one of the most versatile chemical feedstocks and are key components of innumerable synthetic transformations . A particularly active field of catalysis utilizes alkene reactants in hydrofunctionalization reactions such as olefin hydroalkoxylation and hydroamination reactions . A vast majority of these alke...
The peptide nociceptin / orphanin fq (n / ofq) was isolated for the first time in 1995 by two distinct research groups from rat and porcine brain extracts . N / ofq is composed by seventeen amino acids residues, and this peptide was nominated nociceptin due to the hyperalgesic effects that it evokes after supraspinal a...
The morbidity and mortality of liver cancer are increasing . According to who statistics, there are about 1 million new cases of liver cancer per year world - wide . In china, liver cancer accounts for 41% of all new cancer cases annually . With constant technological advancement the adverse effects of radiation interf...
Ionic liquids (ils) are liquids that are comprised entirely of ions, differentiated from typical ionic salts by having melting points below 100 c . Il melting points are low because electrostatic interactions between component ions are weaker and crystal lattice packing is hindered . This is typically achieved by makin...
The female reproductive organs undergo cyclic changes that are associated with intense angiogenesis . Of these reproductive organs, the process of cyclic vascular formation in the ovary is well - studied . In addition, the ovary was the first organ wherein vegf, the most important angiogenic factor such as vegf was fir...
Kidney transplantation (kt) as the treatment of choice for patients with renal failure improves patients' quality of life . However, numerous complications within 1 weeks after transplantation have been reported that complicate administration of medications that are imperatives for prophylaxis of organ rejection or inf...
Cerebral palsy (cp) is the most common cause of childhood disability and is seen in 22.5 out of 1,000 births1 . The non - progressive lesion in the brain that causes cp, has devastating effects on the musculoskeletal system . These effects, like spasticity, imbalance between agonist and antagonist muscles, and decrease...
Spontaneous closure of traumatic carotid - cavernous fistulas (ccfs) by thrombosis of the cavernous sinus is quite rare since these are high - flow fistulas . We recently observed a traumatic ccf that had rapid improvement of symptoms after the event, but it recurred shortly after the resolution of symptoms . The mecha...
Cardiovascular disease (cvd) is a broad term referring to all diseases that involve the heart and/or blood vessels . Cvd is the leading cause of death worldwide, estimated at causing 17.5 million deaths in 2005 . Of these an estimated 7.6 million were due to ischaemic heart disease (ihd) which is a subset of cvd and is...
A 21-year - old male reported to the department of conservative dentistry and endodontics, with a complaint of the fractured crown in the right maxillary central incisor . The clinical and radiographic examinations revealed a loss of tooth structure extending to the cervical third, as well as an exposure of the root ca...
Involvement of the spleen in malaria that results in splenomegaly renders this organ prone to complications such as rupture . In areas where malaria is endemic, spontaneous rupture of spleen is uncommon . Because of increased travel to endemic areas and resistance to anti - malarial drugs, however, malaria is a major m...
According to the world health organization (who) classification, odontogenic tumors are considered to be tumors of the odontogenic mesenchyme, with or without the presence of odontogenic epithelium . Myxomas of head and neck are divided into two forms: i) deriving from facial bone which has also been subdivided into os...
Male volunteer subjects (n 8; bmi 30 (sd 4) kg / m; aged 62 (sd 5) years) with t2d controlled by diet and lifestyle alone or with impaired glucose tolerance (table 1) were recruited from the aberdeen area of the uk . Subjects were only included if they were not on any special religious or prescribed diet and had a stab...
In particular, its main biological actions (mediated through a receptor system present on the sertoli cells) are the following: cellular sperm differentiation, modulation of spermatid morphogenesis, and the maturation of epididymal spermatozoa [110]. The biological actions of fsh are more relevant in the clinical condi...
Caesarean section is one of the oldest procedures performed in the history of surgery . Since the first documented caesarean delivery in 1020 ad, various modifications have been made in the technique . It was surgery performed as a last resort, mostly peri- or post - portem . Initially, the uterine wound developed in c...
The diagnostic process of jawbone lesions is complex since several etiologic factors, histopathological findings, morphological details, and distinct radiographic characteristics are involved16 . Unilocular radiolucent lesions have similar clinical and radiographic characteristics, although they have different histopat...
High - speed afm was operated in tapping mode at room temperature (25 c) with free amplitudes of 1.52.5 nm and an amplitude set point of larger than 90% . Silicon nitride cantilevers, (bl - ac10ds - a2, olympus, tokyo, japan) with nominal spring constants of 0.1 n / m, a resonance frequency of 500 khz, and a quality fa...
Dr . Jacqueline a. noonan originally defined noonan syndrome in 1963 in a study of nine children . There were six boys and three girls that had a rare type of heart defect, valvular pulmonary stenosis and characteristics of their physical appearance included short stature, webbed neck, wide - spaced eyes, low - set pos...
Swollen conidia of the mold aspergillus fumigatus (strain atcc 46645) are generated by pre - incubation in rpmi 1640 (biochrom ag, berlin, germany) supplemented with 5% fcs (v / v). 2x10 resting conidia are resuspended in 5 ml medium and incubated in a 6-well tissue culture plate (tpp ag; trasadingen, switzerland, cata...
The samples are selected, are the students of sree balaji dental college and hospital chennai, tamil nadu with the following criteria, the subjects are selected with age group between 18 and 20 years with complete permanent dentition, including the second molars (at least 28 teeth) all teeth present except third molar,...
Despite numerous preventive measures, exit - site infections (esis) are a common problem in the peritoneal dialysis (pd) population . Esis usually respond well to empiric antimicrobial therapy aimed at gram - positive and gram - negative bacteria . However, if no clinical improvement occurs one should consider other in...
Rice (oryza sativa) was the first crop species selected for whole genome sequencing because of its relatively small genome size (1) and its global importance in food production (2, 3). Draft genome sequences for rice were first produced in 2002 (4, 5), followed by a map - based, nearly complete genome sequence (6), and...
Although some occasional reports of postnatal neurogenesis in mammals have been published during the first half of the twentieth century (see for a review), it was only in the early 1960s that the first evidence of a postnatal neuronal proliferation was reported in various brain regions in adult rats, including the den...
As the development of virtual reality (vr)-based treatment systems such as the interactive binocular treatment (i - bit) system presented by eastgate et al1 and the viston - vr system presented by qiu et al2 have demonstrated, the advent of vr technology has been introduced as a promising solution for the management of...
Phosphate homeostasis is maintained by a complex interaction between vitamin d, parathyroid hormone (pth) and bone - derived fibroblast growth factor 23 (fgf23). Phosphate depletion increases the rate of synthesis of calcitriol, while phosphate loading has the opposite effect [1, 2]. It decreases the 1- hydroxylation o...
All - ceramic restorations have gained considerable attention and popularity due to their esthetic performance and excellent biocompatibility with the increasing esthetic demand of the society . Likewise, high - strength zirconium oxide ceramics (zirconia) have become widely used because of their chemical stability, ph...
Demand among undergraduate, graduate, and postdoctoral trainees for international research experience brings together investigators from increasingly diverse cultural backgrounds in academic research institutions around the world . Educators dedicated to meaningful instruction in research ethics and scientific integrit...
Recently, gender - specific medicine (gsm) has become an active field in current medical care . The field of gsm examines how normal human biology and physiology differ between males and females and how diagnosis and treatment of diseases differ as a function of gender . Males and females differ in their experience of ...
Reduced exercise tolerance in turn leads to self - imposed activity limitation which then leads to deconditioning (accp / aacvpr 1997; gold 2005). Regular exercise training programs, such as those administered through pulmonary rehabilitation programs, consistently improve exercise endurance in patients with copd (gold...
Verruciformxanthoma (vx) is an uncommon benign lesion of adults and was first described by shafer in 1971 . Oral vx presents as a solitary or multiple demarcated, granular lesions exhibiting a flat to papillary or verrucous surface . It can be found in masticatory mucosal sites with a predilection for the gingival marg...
The development of positron emission tomography (pet) has made it possible to detect the physiological process in a human body . [18f]fluoro-2-deoxy - d - glucose(fdg) is the analog of glucose, which is widely used in clinical pet experiment . In order to understand the metabolism of glucose and to detect diseases bett...
L929 mouse fibroblasts and a1 mouse embryonic fibroblasts (parp-1) were maintained as subconfluent culture in high glucose (4.5 g / liter) dulbecco's modified eagle's medium, with 10% fetal calf serum (cambrex corp . ), 2 mm l - glutamine (cambrex corp . ), and 50 units / ml pen - strep (cambrex corp . ). Exponentially...
Teeth are the most durable and reliable tool for forensic age estimation . Various methods can be utilized for age estimation in children as well as in adults by the use of a tooth . The measurement of secondary dentin deposition by dental radiographs is a simple and nondestructive method for age estimation . Several s...
The sniffing position has been thought to be the standard position for direct laryngoscopic view . However, adnet et al . 1 showed no significant advantage of the sniffing position over simple head extension on routine general surgical patients, using the cormack - lehane scale . They found the sniffing position to be ...
Diabetic retinopathy (dr) remains the leading cause of blindness and vision loss among adults aged under 40 years in the developed world . Population - based studies suggest that about one - third of the diabetic population have signs of dr and approximately one - tenth have vision - threatening stages of retinopathy s...
Inflammatory bowel diseases (ibds), which consist of crohn's disease (cd) and ulcerative colitis (uc), are chronic and complicated inflammatory disorders of the gastrointestinal tract . Although the exact etiology of ibds remains elusive, numerous studies have suggested that cd4 t helper (th) cells play important roles...
Pekinensis), which is widely used vegetable in asia, particularly in china, japan, and korea, is rich in vitamin c and minerals such as potassium, calcium, magnesium, and zinc . This subspecies is typical of the brassica a genome and has a large number of genomic resources including a mapping population and bac librari...
Osteoporosis is a skeletal disorder characterized by compromised bone strength predisposing a person to an increased risk of fracture . Bone strength reflects the integration of two main features: bone density and bone quality . While osteoporosis is frequently regarded as a women's disease, up to two million men in th...
Gingival bleeding is a prevalent manifestation of periodontal diseases and also results from direct trauma, viral, fungal or bacterial infection, drugs, pregnancy, dermatoses, and systemic conditions.12 however, persistent gingival bleeding may be due to serious medical conditions such as leukemia and bleeding and plat...
These are usually found in the head, neck and axilla in children, and are most commonly asymptomatic and discovered incidentally [2, 3]. Cystic lymphangiomas arising from the mesocolon are rare in adults and seldom present with acute abdomen . We report a case of cystic lymphangioma of the mesocolon presenting with per...
The online version of this article (doi:10.1007/s00167 - 013 - 2443-x) contains supplementary material, which is available to authorized users . Recent anatomical studies have shown that the size and shape of the femur and tibia at the knee vary significantly among individuals, most notably between males and females [3...
The number of patients with chronic kidney disease (ckd) in japan is approximately 13,300,000, and continues to increase . In addition, the number of end - stage kidney disease (eskd) patients, ie, patients in whom ckd had deteriorated and required dialysis, increased by 7,000 annually . At the end of 2011, the number ...
Resistance to antibiotics belonging to several different classes is escalating and represents a worldwide problem (ginsberg, 2008; dye, 2009; furtado and nicolau, 2010), as both gram - negative and gram - positive bacteria (such as among others staphylococcus aureus, mycobacterium tuberculosis, helicobacter pylori, bru...
Hexavalent chromium (cr) is a toxic metal known for its carcinogenic effect in humans . The lung cancer risk is prevalent in pigment chromate handlers, ferrochromium production workers, stainless steel welders, and chromeplaters1 . Besides occupational cancer, risk of other kinds of adverse health effects are also repo...
Clinical manifestations are similar to the adult, such as frequent lymphadenopathy and pulmonary involvement . The early - onset form exhibit unique clinical triad of arthritis, rash, and uveitis, which typically presented in the first year of life (2 - 5). The early - onset childhood sarcoidosis may be overlooked due ...