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The haemoglobinopathia is inherited autosomally dominant and most affected individuals are heterozygote . Due to the high oxygen affinity of the haemoglobin (hb) molecule, erythrocytosis caused by hb ypsilanti was first described in 1967, and the mutation results in substitution of amino acid (99 asptyr) involved in th... |
Coronary artery disease (cad) is a major cause of mortality and disability worldwide . The major independent risk factors for cad including age, gender, hypertension, cigarette smoking, diabetes mellitus, elevated serum levels of total and low - density lipoprotein cholesterol (ldl - c), and diminished levels of high -... |
Studies of factors related to impairments specific to gait or functional activity have targeted appropriate strategies for gait rehabilitation, and much of this research has been done in a clinical environment1,2,3,4, examining gait rehabilitation based on the impairments of stroke patients5, 6 . Three factors affect t... |
To reveal the function of the uncharacterized smxl sub - clade 2 (figure 1a), we phenotypically characterized single mutant seedlings as well as all possible double mutant combinations and the smxl3;smxl4;smxl5 triple mutant (figures s1a and s1b). In contrast to single mutants, which displayed no obvious phenotypic alt... |
In the field of de novo in silico materials and drug design, fast and accurate methods are required for high - throughput screening of a wide range of systems . Density functional theory (dft) methods are widely used because they are robust, often sufficiently accurate, and universally applicable for most of the less e... |
Numerous epidemiological studies have shown that short - term exposure to particulate matter (pm) air pollution is associated with increased morbidity and mortality, primarily from cardiovascular disease (cvd) (katsouyanni et al ., 2001, kinney and ozkaynak, 1991, schwartz and dockery, 1992). Despite this consistently ... |
Sirolimus is a potent m - tor inhibitor that blocks growth factor - induced transduction signals mediating cell division in the immune response and oncogenesis [13]. Initial randomized clinical studies showed a 50% relative risk reduction in acute graft rejection when sirolimus was used in combination with cyclosporine... |
Pathogens reduce host fitness, and thereby exert a strong and ubiquitous selective pressure on hosts that has led to the evolution of a range of immune responses . Immune responses are elicited when sensors detect the presence of pathogens through pathogen - associated molecular patterns (pamps) or through markers of p... |
A 42-year - old mexican - american man with diabetes presented to the emergency room with a 3-day history of left foot swelling, redness, and pain associated with nausea, fever, and chills . The patient was initially managed with oral analgesics and antibiotics and referral to a wound care center for debridement and dr... |
Chemokines are a family of small cytokines that regulate leukocyte migration by inducing chemotaxis of specific cells . Chemokines are produced in almost all eukaryotic cells that constitute blood and other tissues . For example, chemokines of the cc subfamily are secreted by epithelial cells and fibroblasts during inf... |
The question as to whether to provide resuscitative efforts at borderline gestational age has for many years been acknowledged as a difficult ethical dilemma, with neonatologists commonly deferring to informed parents in this situation . That is, once the risks of death and disability have been reviewed, neonatologists... |
Because the gluteus maximus (gm) muscle fibers are aligned perpendicular to the sacroiliac joint, gm contractions compress the sacroiliac joint, and contribute to pelvic stability1 . Gm contraction also contributes to the transmission of force from the lower extremity to the pelvis through the sacroiliac joint during f... |
Allergic rhinoconjunctivitis is a common allergic respiratory disorder caused by allergens such as grass or tree pollens and house dust mites . The prevalence of allergic rhinoconjunctivitis is increasing and is a major health issue worldwide . In europe and the us, up to 20% of the adult population suffers from this c... |
The fluoroquinolones have also become popular as there are minimal chances of bacterial resistance with these agents . Inspection of the pharmacokinetic behavior in various animal species reveals that the drug is poorly absorbed in goats following its oral administration . One practical approach to enhance the bioavail... |
Neuropathic or deafferentiation pain which occurs in post - herpetic or trigeminal neuralgia, also responds to antiepileptics such as phenytoin, carbamazepine, and gabapentine . Aromatic anticonvulsants [phenytoin, phenobarbital (phenobarbitone) and carbamazepine] are the most frequently involved drugs for cutaneous ad... |
Smoking is thought to produce an appetite - suppressing effect by many smokers, particularly in adolescents . Most smokers want to stop smoking, but the fear of body weight gain might outweigh the perception of potential health benefits associated with smoking cessation, particularly in women . For instance, female stu... |
The improvement of health care support has greatly extended the average life expectancy, which has resulted in a substantial increase in the number of individuals aged 65 years and above . Memory impairment is the usual consequence of the ageing process in the elderly1 and can be a marker of alzheimer s disease (ad)2 a... |
In spite of the recent advances in the understanding of the pathophysiological processes in chronic heart failure (chf), this condition remains a heterogeneous syndrome with an overall poor prognosis . Chf is characterized by left ventricular dysfunction, impaired vascular tone, and skeletal muscle changes, contributin... |
Few poisons induce fever, and few of these were available in alexander's time except plant salicylates, which disturb temperature regulation; alkaloids, which interfere with perspiration; and ergot mycotoxins, which produce a subjective sensation of heat . Plutarch mentions that aristotle (alexander s tutor) procured a... |
Glucose-6-phosphate dehydrogenase (g6pd) deficiency is an inherited, x chromosome - linked, metabolic disorder . Its reduced concentration renders erythrocytes susceptible to hemolysis under oxidative conditions such as ingestion of fava beans or certain drugs such as chloramphenicol, sulfonamides, analgesics, isoniasi... |
Calcifying fibrous tumor (cft) is a rare, usually solitary, benign tumor of uncertain etiology . We report an incidentally detected case of cft arising from the small intestine and associated mesentery . A 45-year - old man with no significant past medical history presented to a local emergency room with severe left gr... |
Multiple sclerosis (ms) is an inflammatory, demyelinating, immune - mediated, and debilitating disease that affects young adults and is often associated with significant disability and impaired quality of life [1, 2]. Disability and high morbidity are common features of the disease; symptom management must therefore be... |
Indian aquaculture production consists mainly (~70%) of three major carps, labeo rohita, catla catla, and cirrhinus mrigala . Intense culture practices generate potential environmental stressors that lead to high susceptibility of captive fish species to various diseases, including viral, bacterial, fungal, and parasit... |
To evaluate the treatment efficacy of epidural blood patch (ebp) in treatment - refractory low csf (cerebrospinal fluid) pressure headache . Although first described in 1938 low csf pressure headache is still an under - diagnosed headache disorder . This being partly due to unfamiliarity, and with the overlap with othe... |
A number of genetic alterations have been shown to play a role in the development of follicular cell - derived thyroid cancer . These point mutations and translocations occur in genes of several important signaling pathways, particularly that of the mitogen - activated protein kinase (mapk) pathway . The mapk signaling... |
Carassius auratus is, ecologically warm - water teleost species, belonging to class actinopterygii, family cyprinidae, widely inhabited the lakes, brooks, rivers and marshes under the natural ecosystem throughout the northeastern asia region in countries in china, taiwan, japan and korea (kim & kang, 1993; choi et al .... |
Anencephaly is a devastating yet common neural tube defect which occurs due to the failure of closure of rostral pore of the neural tube that leads to exposed undifferentiated neural tissue . Meroanencephaly is the classic form which presents as a lack of cranial vault bones and exposed dorsal undifferentiated dorsal n... |
Erectile dysfunction (ed) and lower urinary tract symptoms / benign prostatic hyperplasia (luts / bph) increase concomitantly with increasing age, negatively affect quality of life (qol), and have a common pathophysiology . Over the years, four possible pathophysiological mechanisms have been proposed to explain the li... |
Rheumatoid arthritis (ra) is characterized by chronic synovial inflammation of unknown cause . Around 1% of adults are affected by ra worldwide, and the incidence appears to be higher in women . Failure to control active ra induces joint destruction, deformities in the extremities, deterioration of quality of life (qol... |
Severe sepsis, an overwhelming inflammatory response to an underlying infection, remains a lethal disease that is present in over a third of european intensive care patients . In previous studies this group reported a link between gene expression of specific immune regulatory cytokines in peripheral blood mononuclear c... |
Depression is nt just one of the illnesses described earlier in the history of medicine, but in most often mental disorders today (1). Ranges from very mild condition that borders to normal to an serious depression with a belief in something that is nt true . Depression is a disease characterized by lowered mood under ... |
Scrub typhus was suspected by clinical manifestations such as febrile illness or fever with rash or eschar . After giving informed consent, patients filled out questionnaires about potential chigger exposure and symptoms or signs consistent with scrub typhus . Blood samples were taken from all patients for total blood ... |
Hepatitis c virus infects primarily the hepatocytes, leads to the development of fibrosis or cirrhosis of the liver, and is a significant risk factor for the development of hepatocellular carcinoma (hcc). Human interleukin-17 (il-17) producing cd4 t cells, th17, comprise a proinflammatory t cell subset . Previous studi... |
Preterm birth is responsible for approximately 75% of all neonatal deaths and 50% of childhood neurological morbidities.1,2 preterm birth is also associated with both high immediate and long - term costs after discharge from the hospital.3 infants born at less than 28 weeks spend 85 times as long in hospital as full - ... |
Of 5,208 randomly selected participants aged 1875 years from the prevalence, prediction, and prevention of diabetes (ppp)-botnia study (2), representing the adult population residing in the botnia region of western finland, 206 individuals with previously diagnosed and 100 individuals with newly diagnosed diabetes were... |
For playback experiments, we used a previously described experimental system, where vibrations were played back near to vacant artificial pupal cells . In brief, a plastic container (30 cm 7 cm 7 cm) was filled with humus soil and two artificial cells were prepared by briefly thrusting a test tube (3 cm in diam .) Into... |
Two cats were evaluated for progressive exercise intolerance, dyspnea and unilateral infiltrate of the left lung . Computed tomography angiography (cta) revealed absence of the right pulmonary artery in both cats with systemic arterial collateral vessels perfusing the right segmental pulmonary arteries . In one case, t... |
Although evidence supports the importance of lifestyle in promoting health, many people still have unhealthy lifestyles (3). With the global changes of social and economic patterns, the lifestyle is a collection of attitudes, habits, and desires related to one person or a group (5). Healthy lifestyle is defined as the ... |
Balance is the ability to control and maintain the center of gravity of a body toward the base of support in a given environment1 . Even healthy individuals experience limited function once they lose their ability to balance, and evaluating balance ability makes it possible to predict the risk of falls . The equipment ... |
H and c nmr spectra were obtained in cdcl3 on a bruker drx spectrometer and were recorded at 500 and 125 mhz respectively . Electrospray mass spectra were recorded on a p e sciex api iii triple quadropole mass spectrometer for solutions in methanol . Flash chromatography was carried out using kieselgel 60 (230400 mesh)... |
Thermophilic campylobacter, especially campylobacter jejuni and campylobacter coli, are considered the most common bacterial agent of human gastroenteritis in developed countries . Directive 2003/99/ec (european commission, 2003) establishes the monitoring of zoonoses and zoonotic agent such as campylobacter spp . This... |
Osteoporosis is a significant global public health issue, expected to affect more people worldwide than ever by 2050 . In the united states, it has been estimated that by the end of 2010, approximately 12 million people over the age of 50 years will have osteoporosis with another 40 million being osteopenic . These num... |
Although therapeutic decisions have long been made on the basis that breast conservation treatment (bct) offers equivalent survival outcomes compared to mastectomy for the treatment of breast cancer, a recent analysis suggesting that bct is associated with higher breast cancer specific survival may change that paradigm... |
Neck dissection was introduced in the early 1980s based on analyses of the spreading pattern of lymph node metastases from thoracic esophageal squamous cell carcinoma (scc) [1, 2]. Extended lymph node dissection including neck, mediastinal, and abdominal lymph nodes has been called three - field lymph node dissection (... |
A 58-year - old woman with an eight - year history of hypertension was referred to our institution due to progressive dyspnea . Based on clinical symptoms, the new york heart association (nyha) class of the patient was class iv heart failure despite ten days of intensive medical management . An echocardiogram revealed ... |
Coronary heart disease (chd) is a major public health problem and the leading cause of death in mexico . The role that dietary carbohydrates play in chd risk has recently received particular attention [2, 3]. High carbohydrate intake has been found to have an adverse effect on serum lipid levels and glucose metabolism,... |
Sprague - dawley rats were fed soy - free food during and after breeding, and body weights of each animal were recorded before and at termination of the experiment . Bilateral ovx was performed under isoflurane anesthesia at the age of 3 months, and animals were divided into five groups (n = 1112/group). Food was soy -... |
An exponential increase in hip arthroscopy has been observed worldwide during the more recent years . This is possible partially due to the improvements of surgical instrumentation and the greater knowledge of pathologies such as femoroacetabular impingement (fai).1 hip arthroscopy is not only a less - invasive surgery... |
Therefore, they may inhibit the healing processes and consequently influence the success of the endodontic treatments . In vitro cytotoxicity assays are extensively used in the preliminary testing of new sealers, since such methods are considered simple, reproducible and reliable for biological evaluations . Several ro... |
Renal disease is increasingly recognized as a cause of morbidity and mortality among patients with hiv infection . Longer survival of patients on antiretroviral treatment as well as specific effects of some antiretroviral drugs and viral - related factors contributes to this finding . Traditional risk factors for renal... |
We conducted electronic literature searches (medline, 19502011 september; embase, 19742011 september) for cohort studies that investigated the relationship between pa and acm / cvd risk, where study keywords were thesaurus terms registered in medline (mesh) or embase (emtree) and text words related to diabetes, pa, acm... |
Prematurity is still considered a health issue in the united states . In 2008, 12.3% of live birth prematurity caused 6.27 deaths in each 1000 live births in the united states in 2007 . In 2003, diseases related to prematurity were considered as responsible for 17% of all newborn deaths; it is estimated that half of th... |
Its incidence is predominantly high in northern india, other asian countries, and in certain places in the western hemisphere . It has been reported that 90% of oral cancers in india among men were attributable to chewing and smoking habits . In india, oral squamous cell carcinoma develops through a multi - step proces... |
Apicomplexa are a phylum of unicellular eukaryotic organisms that often parasitise multiple animal hosts during their life cycles . This group of obligate intracellular parasites are so called because the invasive zoite stages possess a characteristic cell apex containing several secretory organelles and associated cyt... |
Invadopodia are extracellular matrix (ecm)-degrading membrane protrusions present in invasive / motile cancer cells and used to degrade components of extracellular matrix in order to cross into new environments . Invadopodia were identified in a number of invasive (solid) cancer cell lines, such as breast, head and nec... |
Cognitive deficits are increasingly being acknowledged as an important feature of schizophrenia (heinrichs, 2005) and, hence, as a potential therapeutic target . Moderate to severe cognitive impairment is frequently observed in schizophrenia both in early and chronic phases with a substantial impact on the global funct... |
As this special issue shows, the number of public bioinformatic tools and web servers is growing quickly . However, the wealth of powerful tools and servers is, in our opinion, only utilized by a fraction of biologists who would be able to profit from them . Especially for non - experts it can be very time - consuming ... |
Grow mouse es cells in 10 cm cell culture plates with mouse es cell medium supplemented with lif . When es cells are ready for use (generally at 50 - 70% confluence), remove es media and rinse cells once with 5ml sterile pbs . Add 2ml 0.05% trypsin / edta to each plate and incubate plates at 37c for 35 minutes, quench ... |
Fibrolamellar hepatocellular carcinoma (hcc) is a rare liver tumour . In contrast to conventional hcc it usually affects young adults or adolescents, is characterised by a slow evolution and the lack of increase of -foetoprotein (-fp) level . Although the treatment mainly consists of surgery, metastatic relapse is asso... |
Hepatocellular carcinoma (hcc) remains a frequent and highly lethal type of cancer.1,2 according to the most recent data, the global incidence of hcc is still increasing, although it varies throughout the world; in 2013, 818,000 global deaths were caused by liver cancer, 9% more than that in 2010 (752,000 global deaths... |
Minneapolis, mn, usa) is a stentless valve with an effective orifice area that is larger than that observed on other bioprostheses . However, there have been sporadic reports of structural valve deterioration (svd), such as aortic root wall rupture, leaflet tearing, and pseudoaneurysm formation . The medtronic freestyl... |
Time- and frequency - resolved vibrational spectroscopy (either with infrared or raman probes) has long been used to monitor structural rearrangements of atoms . Unique marker bands that serve as fingerprints of excited state photoreactions or nonadiabatic relaxation dynamics allow to resolve transient reaction interme... |
The anti - vaccine movement has been using the internet and social media to communicate their message since the inception of these technologies . The virtually ubiquitous use of digital media and smartphones by children, however, also creates an ideal channel for public health officials to communicate their own positiv... |
Since the discovery of carbon nanotubes (cnts), a number of applications have been studied to take advantage of their superior thermal,1 mechanical,2 and electronic properties.3 cnts have been highlighted as promising materials for applications such as composites,4 supercapacitors,5 and gas and toxin sensors in the foo... |
Mycophenolate mofetil (mmf), a commonly used immunosuppressive drug in solid organ transplantation, has resulted in a significant decrease in allograft rejection . Mmf is an antimetabolite that inhibits inosine monophosphate dehydrogenase, resulting in blockade of the de novo pathway of purine synthesis . Because this ... |
. External dcr should establish a low - resistance drainage pathway between the conjunctival tear sac and the nasal cavity, by conversion of the lacrimal sac into part of the lateral nasal wall (1). In 1921, dupuy - dutemps and bourguet (2) described the technique of external dcr . In this procedure, the lacrimal sac w... |
This automatic system is controlled by reflex mechanisms in the limbic system of the brain and brainstem . Dysfunction may also be engendered by faulty neurotransmission in the peripheral distribution of autonomic nerves . The sympathetic, or thoraco - lumbar outflow system, activates physical and mental action and its... |
Uranium is an environmental contaminant that arises as a result of authorized and accidental releases at various stages in the nuclear fuel cycle, including from uranium ore mining activities and post - reactor operations . Additionally, in many countries, uranium - containing radioactive wastes, including spent nuclea... |
Tuberculosis (tb) is a major health problem with a global mortality ranging from 1.6 to 2.2 million cases per annum . According to the who estimates, mycobacterium tuberculosis can involve any organ, and clinical features depend on the organ system involved . Liver involvement in tb, though common both in pulmonary and... |
The cytostatic drug 5-fluorouracil (5-fu) is used for the treatment of malignant tumors of the gastrointestinal tract, the head and neck region as well as breast cancers . For development of 5-fu cardiotoxicity, several different causative mechanisms like occurrence of coronary artery spasm, direct non - ischemic toxic... |
Intravascular papillary endothelial hyperplasia (ipeh) is an unusual benign vascular lesion comprising approximately 2% of the vascular tumors of the skin and subcutaneous tissue . The term intravascular papillary endothelial hyperplasia is the most descriptive and least confusing and is the one most frequently used in... |
Faded mice were maintained as a congenic strain of c57bl/6j mice (c57bl/6j - fe / fe) in the experimental animal center at hallym university, korea . The inbred strain cba / j was introduced from nagoya university, japan, and was subsequently maintained in our laboratory . The animals were maintained at 222 temperature... |
Influenza has a significant clinical impact in immunocompromised patients, including adults with cancer, and can cause severe complications . In particular, patients after hematopoietic stem cell transplantation and those undergoing chemotherapy for leukemia are at highest risk, with high morbidity from complications, ... |
The vector - borne protozoal parasite trypanosoma cruzi is the etiologic agent of chagas disease in humans and domestic canines . Vectors of t. cruzi, blood - feeding triatomine insects also called kissing bugs, are found throughout the americas, including texas (kjos et al ., 2009). Infection with parasites may occur ... |
Isolated adrenocorticotropic hormone (acth) deficiency (iad) is very rare and difficult to diagnose . Iad was first described in 1954 and is a rare cause of secondary adrenocortical insufficiency (1). In japan, the prevalence of iad is 19.1 per one million and the incidence is 0.9 per year (2). It usually presents with... |
According to the updated recommendations of the international committee of medical journal editors (icmje), " duplicate publication is publication of a paper that overlaps substantially with one already published, without clear, visible reference to the previous publication " (1). For example, editors of influential ca... |
Details of case ascertainment, processing and genotyping, together with sample and genotyping quality control are provided in the supplementary information . Statistical methods developed for testing the reliability of externally generated data sets, detecting samples with non - european ancestry, correcting for struct... |
The hong kong diabetes registry was established in 1995 as part of a continuous quality - improvement program at the prince of wales hospital, hong kong . Between 1995 and 2005, a total of 7,838 patients from community and hospital clinics, as well as patients newly discharged from the hospital, was enrolled in this re... |
Nfat signaling controls multiple steps in the development of the cardiovascular system . In the embryonic heart, nfatc1 is initially expressed broadly, but by e11.5 becomes restricted to cells that will eventually form the heart valves . Nfatc1 mice have defective heart valve development and abnormalities in the cardia... |
Severe cardiovascular disease (cvd) is a condition that constitutes the highest mortality in the united states (us). However the risk of perioperative death is real, and it is most acute for those with heart failure or advanced age . As such, surgeons routinely inform patients of the possibility of death due to surgery... |
Over the last decades, analytical quality assurance has gained in importance in many scientific areas, including the analysis of radioactive specimens . The use of certified reference materials is an important pillar for the assessment of the quality of any acquired analytical data . Such matrix - matched certified ref... |
Thoracic duct cysts in the mediastinum are rare, with 23 cases reported to date . We present the case of a gentleman who was found to have multiple thoracic duct cysts during investigation of a large thyroid goitre with retrosternal extension . Other reported cases of thoracic duct cysts are of a single large swelling ... |
Airway inflammation, together with bronchial hyperresponsiveness and airway structural remodelling, is one of the prominent features of asthma, a phenotypically heterogeneous chronic respiratory disease that affects over 300 million asthmatic people worldwide, who will probably become more than 400 million by 2020 [15]... |
Hepatoblastoma (hb) is an uncommon primary malignant hepatic tumor in children, primarily affecting infants . Usual presentation is an abdominal mass and rarely as virilization due to ectopic sex hormone production . Different histological types like pure epithelial, mixed, macrotrabecular, and small cell anaplastic ar... |
A drug interaction can be defined as an interaction between a drug and another substance that prevents the drug from performing as expected . This definition applies to interactions of drugs with other drugs (drug - drug interactions [ddis]), as well as drugs with food (drug - food interactions) and other substances . ... |
Endobronchial ultrasound (ebus)-guided transbronchial needle aspiration (tbna) is widely accepted as the modality of choice for obtaining cytological specimens from mediastinal and hilar lymph nodes . It is a useful tool not only for the staging of lung cancer but also for the diagnosis of diseases such as sarcoidosis,... |
The philadelphia (ph) chromosome (derivative chromosome 22), resulting from a translocation between chromosomes 9 and 22, was the first disease - specific chromosomal abnormality to be associated with a malignancy, namely, chronic myelogenous leukemia (cml). Advancements in cytogenetic and molecular methods have led to... |
A 77-year - old woman (height, 155 cm; weight, 50 kg) with severe back pain and radiating pain in both legs was scheduled for lumbar discectomy under the diagnosis of l4 - 5 spinal stenosis . She had been able to perform basic activities of daily living despite a functional capacity of less than 4 metabolic equivalents... |
The critically ill polytrauma patient requires a multidisciplinary management due to the complexity of injuries . The most common injuries are represented by traumatic brain injury, spinal cord injury, traumatic injuries of the lung parenchyma, abdominal traumas, traumatic injuries of the pelvis and of extremities, and... |
Dispersants are important options in the tool box for responding to marine oil spills . Developed after initial attempts to disperse oil with simple industrial cleaners (national research council 1989), current products are carefully blended mixtures of usually food - grade surfactants and solvents (national research c... |
Restorative proctocolectomy with ileal pouch - anal anastomosis has become a standard procedure for patients with familial adenomatous polyposis (fap) and chronic ulcerative colitis . A good long - term pouch function is to be expected in> 90% of patients . Pelvic sepsis following this procedure has been reported in up... |
Clostridium difficile infection (cdi) is still associated with considerable morbidity and mortality, with symptoms ranging from mild diarrhoea to toxic megacolon . Since 2007, the department of health in england and wales has introduced mandatory reporting of all c. difficile toxin positive samples and hospital targets... |
A 54-year - old female jw patient (body weight, 50 kg) diagnosed with liver cirrhosis complicated by hepatitis b viral infection presented to the bloodless center in our institute to assess whether ldlt was possible . Initial laboratory findings were hemoglobin (hb) of 8.1 g / dl, platelets 51 10/l, prothrombin time (p... |
Investigations involving role of monomeric g proteins in signalling pathways is still at its early stage . This review is an attempt to understand the role of two monomeric g proteins - dexras1 (dexamethasone - induced ras - related protein 1) and rhes (ras homolog enriched in striatum) in modulation of various pathoph... |
Hydroxyl radical (oh) is a major reactive intermediate produced when water is exposed to ionizing radiation . Its reactions with dna constitute the indirect effect of ionizing radiation and account for as much as 85% of the damage imparted upon the molecular carrier of genetic information in cells . Feedta (and similar... |
The apical limit of obturation and the root canal sealer may influence the final outcome of the endodontic treatment . It has been observed that best results are obtained when the filling material does not overextend beyond the apical foramen . (1963) reported clinical success in 70.6% of overextended root fillings, 86... |
Monkeys were housed at new england regional primate research center (nerprc), southborough, ma . The animals were maintained in accordance with standards set forth by american association for accreditation of laboratory animal care . Thirty mamu - a*01, mamu - b*01, and mamu - b*17-negative rhesus monkeys were distribu... |
Erythema elevatum diutinum (eed) is a chronic and rare dermatosis that is considered to be a variant of leukocytoclastic vasculitis . Clinically, it is characterized by symmetrical, persistent nodules, and plaques over the extensor aspects of both upper and lower extremities with a predilection for the joints particula... |
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