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Hypertension is common in hemolytic uremic syndrome (hus), and often difficult to control in an acute stage . Malignant hypertension associated with hus leads to reversible posterior encephalopathy syndrome, seizures, heart failure, and other adverse consequences which increase the morbidity and mortality of the diseas... |
In 2009, a 52-year - old woman presented with a single lesion on her nose, which started as a papule, referred to sedighe tahereh clinic, isfahan, iran . The lesion had existed for a period of 14 months and was slowly increasing in size, enlarging to a plaque . The diagnosis of leishmaniasis was confirmed with a positi... |
A 60-year - old man was admitted because of visual disturbances and ocular pain following penetrating keratoplasty in the right eye for a corneal chemical burn . On slit lamp examination, we observed a feather - like corneal opacity, corneal infiltrations, and epithelial defects . Subconjuctival amphotericin b (1 mg), ... |
Liver plays a pivotal role in detoxification of xenobiotics, environmental pollutants, and chemotherapeutic agents . For this reason, this organ acetaminophen (apap) is a widely used antipyretic and analgesic which is currently the most frequent cause of drug - induced hepatic failure in the united states with intentio... |
Melamine (2,4,6-triamino-1,3,5-triazine, cas #108 - 78 - 1) was first prepared and described by liebig in 1834 (1) and has since become an increasingly important chemical commodity . Most of the melamine production is used in the fabrication of melamineformaldehyde resins (2). The first analytical methods related to fo... |
Fatigue is a transitional state between awake and sleep which manifests itself as lack of alertness and deteriorated mental or physical performance and often associated with drowsiness . Road accidents due to fatigue are often much more severe than other crashes, since the driver reaction time increases (1). Driver fat... |
There are many published reports of malfunction of the inner tube of the bain co - axial circuit, with potentially lethal complications for the patient . The following case report describes a case where profound hypercapnia occurred consequent to avulsion of the inner tube of the co - axial circuit at the machine end o... |
We attempted to estimate the perceived degree of urgency of the visit and to identify reasons for seeking non - urgent care in the ped by patients and parents . A prospective survey was completed by parents (for children 17 and younger) and patients (18 - 21) presenting to a suburban academic ped that sees approximatel... |
Suicide of which the literal meaning is to kill oneself is an act of intentionally causing one's own death . The reasons are mostly related with some mental disorders such as depression, bipolar disorder, schizophrenia, alcoholism, or sometime drug abuse . The triggering factor is stress which is many times related wit... |
Single - cell microorganisms (scm) constitute an emerging alternative to source high - value lipids for a series of growing markets demanding low - cost, high - quality alternatives . Scm as a broad class display a series of advantages when compared to plants and animals as lipid sources . In addition to being more gen... |
Large elastic arteries in the central region and medium - sized muscular arteries have two functions, i.e., they act as low resistance conduits and as flow pulsation buffers (1). Moreover, a reduction in buffering capacity may increase systolic blood pressure (bp), left ventricular afterload, and pulsatile flow in capi... |
With cataract surgery regarded as the most widely performed surgical procedure, a demand exists for continued innovation and technology . The latest advances evolved through application of well - defined principles to current surgical goals and patient expectations . For example, femtosecond laser technology emerged af... |
Epilepsy is the most common serious neurological disorder of young people affecting nearly 3.4 million individuals in europe . Societal costs are considerable as individuals with medically intractable seizures make up a third of the epilepsy population . More than eu15 billion is spent annually on the treatment of epil... |
After getting the university ethics committee's approval, a prospective case - control study was conducted . All patients who admitted to the boo - ali hospital, zahedan, southeastern iran, with a clinical suspicion of pulmonary tuberculosis or non tuberculous pulmonary infections from september 2006 to august 2007 wer... |
A 14-year - old, domestic shorthair cat was treated for transient diabetes mellitus for 3 months with glargine insulin, which was discontinued when the diabetes mellitus resolved . Approximately 36 months later the diabetes mellitus recurred and glargine insulin was restarted . Within 23 mins of the first injection the... |
Furthermore, it is the most common cause of antenatal hospital admission.1 the incidence of preterm birth rate in us was 12% in 2011.2,3 at siriraj hospital, a tertiary care in central part of thailand, the preterm birth rate was 9.4% in 2004 and 13.7% in 2010.4 srinagarind hospital is another tertiary care center in n... |
Achalasia is a primary esophageal motor disorder of unknown etiology characterized by selective loss of inhibitory neurons in the esophageal wall, resulting in insufficient relaxation of the lower esophageal sphincter and loss of esophageal peristalsis.1,2 jackhammer esophagus is a newly introduced term to describe pat... |
The international cancer genome consortium (icgc) is a multidisciplinary, multi - institutional collaborative effort aiming to systematically and comprehensively characterize somatic mutations in 50 different cancer types and subtypes (1). Five hundred tumor genomes, as well as matched normal control genomes for each c... |
A 64-year - old male patient who had been on diabetes medication with no other particular medical history visited the clinic for symptoms of chillness, and his temperature was measured to be 38.8. an abdomical ct revealed a 6-cm abscess surrounding a pseudoaneurysm of about 4 cm near the right internal iliac artery, an... |
Microarray data is deposited at the ncbi gene expression omnibus (geo) database under geo series accession number gse52552 (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=gse52552). To gain insight in the mechanisms of complement resistance in m. catarrhalis, the transcriptional response of m. catarrhalis strain bbh... |
Rectal varices are not an uncommon manifestation in cirrhosis with portal hypertension . However, serious bleeding from rectal varices is uncommon . Because of its rarity, several authors have reported the utility of transjugular intrahepatic portosystemic shunt (tips) placement to control such bleeding when local ther... |
With an ageing population, alzheimer's disease (ad) and related neurodegenerative disorders represent a serious social and economic threat to most societies . The cost of caring for an increasing number of people with dementia continues to rise . At present, there are an estimated 30 million people with dementia worldw... |
As the number of patients with unruptured cerebral aneurysms has increased, more attention has been given to the primary prevention of the aneurysm rupture4). Endovascular intervention, one of the major treatment modalities, has begun to catch up with and surpass the surgery in the number of cases treated, based on the... |
Red eye is a common eye sign / symptom presenting to the general physicians, other eye care workers, and the ophthalmologist . This symptom accounts for approximately 15% of consultations for ophthalmologists and 6% for general medical practitioners in eastern europe . It also accounted for 40% of all outpatients seen ... |
Auricular acupuncture is a diagnostic and treatment system based on normalizing the body's dysfunction through stimulation of points on the ear . Resulting amelioration of pain and illness is believed to be through the reticular formation and the sympathetic and parasympathetic nervous systems (1). Ear acupuncture, is ... |
In this dataview, we look at the sponsors of health care, providing statistics on business, household and government health spending . The companion article, national health expenditures, 1995 (levit et al ., 1996) presents health care expenditure data in an accounting structure that describes the size, current growth ... |
It can be developmental or acquired and rarely may be associated with temporomandibular joint (tmj) ankylosis . It has been only occasionally reported since then, probably due to its usually asymptomatic nature . In 1941, hrdlicka reported the first cases of bmc in 21 specimens from an unspecified number of dried skull... |
This retrospective study included 343 glaucoma subjects who were examined at the glaucoma clinic of the asan medical center . Patients who met our inclusion criteria of at least three years of follow - up and seven or more reliable vf measurements were consecutively enrolled by medical record review . Eyes that underwe... |
Diabetes is the most common metabolic disease, with an increasing prevalence that reduces life expectancy to a third (1, 2). There are 200 million people with diabetes worldwide (about 5% of adult population) (3). According to a nationwide study in 2001, the prevalence of diabetes in iran was estimated at 4.67% among t... |
We first tested the proposed strategy by designing a symmetric rna dna hybrid dx motif (fig ., there are two parallel hetero - duplexes that are joined together at two points where strands cross over from one duplex to the other . The dx motif is composed of five nucleic acid strands: one central, long, two times repet... |
Consequently, safer alternative anti - inflammatory agents to prevent and treat excessive postoperative inflammation and pain following cataract surgery would be advantageous . Cyclo - oxygenase (cox) is an important enzyme in the inflammatory process and catalyzes the biosynthesis of prostaglandins and thromboxanes fr... |
Malaria, which is caused by a protozoan parasite of the plasmodium genus, represents a serious global health concern given that nearly half of the world population is at risk of infection (who, 2014). Although several anti - malarial drugs for treating the symptomatic stage (or blood stage) of malarial infection are co... |
Governments across the developed world are concerned with enabling older people to maintain their active contribution to society, and thereby their quality of life (qol).1 qol has become a commonly used end point in the evaluation of multisector public policy, including health, social, community and environmental polic... |
Myiasis, the infestation of organs and tissues of human and animals with fly larvae, is a common phenomenon especially in people of tropical and subtropical areas . In spite of occasional reports of obligatory myiasis, the majority of reported cases are facultative myiasis and more than a dozen families of flies can ca... |
Although malaria is preventable and curable, it still causes high morbidity and mortality (1). According to the recent 2013 who report, globally an estimated of 3.4 billon people are at risk of malaria . In this report, who estimated 207 million malaria cases and 627,000 deaths occurred globally in 2012 (2) the majorit... |
The fundamental problems with the personality disorders (pd) diagnostic system in the previous version of dsm, such as all - or - nothing diagnostic categories, considerable heterogeneity within categories, extensive overlap or comorbidity among categories, indistinct boundaries with normal personality, and incomplete ... |
Homeostasis of the brain is maintained owing to its rigidly controlled communication with the peripheral tissues . Entry of metabolites from the periphery to the brain is controlled by the blood brain barrier (bbb). The major structural constituents of the bbb are the cerebral microvascular endothelial cells, and their... |
Focal and diffuse mesangial proliferative glomerulonephritis reveal the most common histologic lesions observed on renal biopsies from patients with iga nephropathy (igan). However, histologic variability is also observed in this disease, which is the same as with lupus nephritis . In some cases, endocapillary hypercel... |
Chronic total occlusion of coronary arteries (cto) is observed in 35%50% of patients with significant coronary artery disease (cad) undergoing diagnostic angiography . Percutaneous coronary intervention (pci) for cto has become a widely accepted treatment strategy and accounts for up to 20% of all pcis [36]. Successful... |
Ocular cicatricial pemphigoid (ocp) is an uncommon, chronic autoimmune disease that affects mucous membranes, particularly the conjunctiva.1 the disease typically results in chronic conjunctivitis and causes conjunctival and corneal scarring, which can result in limbal stem cell deficiency and blindness.2 adequate cont... |
The incidence of endometrial cancer has remained stable, but the number of deaths annually from this disease has doubled since 1987 . Despite the fact that many gynecologists believe endometrial cancer is harmless, when compared stage by stage, 5-year survival is identical to that of cervical cancer, which is considere... |
Genetic analysis of phenotypes and diseases has traditionally followed two approaches: family - based linkage analysis and population - based association studies . While in linkage analysis it is the co - segregation of alleles in families that is measured, population - based studies use non - random associations betwe... |
Acyl - coa thioesterases (acots) represent a group of enzymes that metabolise acyl - coa esters to their corresponding non - esterified fatty acid and coenzyme a (coash). In addition to' acyl - coa thioesterases', these enzymes also have been described as' acyl - coa hydrolases',' acyl - coa thioester hydrolases' and' ... |
A colony was established from soybean and cowpea field collections of n. viridula in stoneville, ms, during the spring and the summer of 2010 . This colony has been maintained in culture for 5 years at the usda - ars national biological control laboratory . After approximately 40 generations in culture, three orange mo... |
Peritoneal dialysis (pd) therapy has increased in popularity since the end of the 1970s . The method was developed as an alternative to hemodialysis (hd) presenting a patient survival rate equivalent to hd and better preservation of residual renal function . Currently, the two principal causes of technique failure in o... |
The incidence of this cancer varies throughout the world with the highest rates in developed communities (1). The gold standard for detection and surveillance of bladder cancers are cystoscopy and urine cytology (2). Despite its benefit, cytology has low sensitivity, particularly for detection of low grade cancers and ... |
Spinal dural arteriovenous fistula (sdavf) is a rare neurological disease with an estimated frequency of 510 cases per million per year . It is caused by a subdural shunt between a radiculomeningeal artery and a radicular vein, leading to impaired venous drainage from the spinal cord and the arterialization of the vein... |
The world health organization (who) has estimated that about 17 million people die annually from cardiovascular disease worldwide, which accounts for approximately 33% of all deaths . In addition, 9.4 million deaths are attributed to complications of hypertension . According to who statistics in 2008, hypertension was ... |
The vast majority of cancers in the oral cavity are squamous cell carcinomas (scc)its evolution is influenced by host immune response cells (e.g., cd8 t, cd4 t, natural killer cells - nk, dendritic cells - dc, macrophages, and eosinophils). The eosinophils are considered as destructive effector leukocytes with cytotoxi... |
The kcps is a prospective cohort study of korean government employees, public and private school teachers, and their dependents who were insured by the korean medical insurance corporation, the former national health insurance corporation (16,17). The cohort includes 1,329,525 koreans (846,907 men and 482,618 women) ag... |
In october 2011, the u.s . National science advisory board for biosecurity (nsabb) was asked to review two papers for their potential as dual - use research of concern (durc). These papers contained results on the adaptation of the highly pathogenic avian influenza a / h5n1 virus to mammalian hosts such that it could b... |
Pneumococcal infections are especially dangerous for children and adults with immunodeficiencies, such as hiv, or with illnesses such as chronic cardiac disease and diabetes.1 pneumococcal vaccination has therefore been recommended for persons at high risk of severe illness or complications . Asthma was first identifie... |
According to protocol analysis of co - variance reduced - antigen - content diphtheria tetanus and acellular pertussis vaccine filamentous hemagglutinin geometric mean concentration serious adverse event total vaccinated cohort pertussis is a highly infectious disease and remains an important worldwide public health pr... |
To identify the possible barriers to the implementation of pharmaceutical care among community and hospital pharmacists in enugu state using nsukka and enugu metropolis as a case study . The questionnaires were distributed to community and hospital pharmacists from designated areas during one of their quarterly meeting... |
We retrospectively evaluated 128 consecutive young adults who were under 40 years of age and who had undergone a ccta evaluation with 64-slice multidetector ct (mdct) as a screening test for detecting cad during a general health evaluation from january 2006 to may 2008 . We excluded 16 subjects who had chest pain or di... |
Several risk factors such as contact lens wear, trauma, ocular surface disease, ocular surgery, and systemic disease have been reported to predispose patients to corneal infections . Management of microbial keratitis commonly involves obtaining corneal scrapings for microbiological studies, and then, empiric broad - sp... |
The human rights act of 1977 followed by the privacy act of 1982 were the first legislative acts to protect personal information across the canadian public sector (peekhaus 2008). In 1987, at a time when the hiv epidemic was gaining momentum across canada, the freedom of information and protection of privacy act was th... |
In 2005, cardiovascular disease (cvd) was the underlying cause of death in 864,480 of the approximately 2.5 million total deaths in the united states [1, 2]. Cvd is the leading cause of death and the most costly disease in america and is expected to increase in costs to $1.48 trillion by 2030 . Although the focus has b... |
The mycotoxic nephropathy (mn) is a renal disorder caused by alimentary ingestion of secondary fungal metabolites possessing nephrotoxic properties and encountered in feeds / foods / forages made mainly from cereals or fibrous plants, and kept in storehouse conditions and increased humidity . Since its discovering the ... |
Distal anterior cerebral artery aneurysms, also known as pericallosal artery (pa) aneurysms, are located on the anterior cerebral artery distal to the anterior communicating artery . These aneurysms represent approximately 6% of all intracranial aneurysms and 4% of those that rupture49). Furthermore, they were similarl... |
Cardiac implantable electronic device (cied) implantation continues to grow with permanent pacemaker implantation in the usa increasing by 56% between 1993 and 2009 . In europe, there has been a 75 and 115% increase in implantable cardiac defibrillator (icd) and cardiac resynchronization therapy pacemaker / defibrillat... |
The incidence of age - related diseases is rising, seriously affecting the health of millions of people around the world . According to the united nations (un) and the world health organization (who) musculoskeletal, rheumatic, and arthritic conditions are leading causes of morbidity and disability throughout the world... |
A patient's journey may begin with transfer from an ambulance to the emergency room and then sometimes continues to surgery and intensive care followed by a general ward . Intensive care is designed and meant for the sickest patients with potential life threats and vital organs dysfunction; it requires advanced monitor... |
Microglia are macrophage - like resident immune cells in the central nervous system (cns) and possess both neurotoxic and neuroprotective function . Microglia accumulate in the lesions of a variety of neurodegenerative disorders, such as alzheimer's disease (ad), parkinson's disease, and multiple sclerosis, and are tho... |
We conducted a qualitative study during september and november 2006, in a peri - urban community on the outskirts of cape town, south africa . This township emerged during the last two decades because of rapid in - migration and is today a permanent fixture of formal and informal dwellings, where many of the younger ge... |
In the previous issue of critical care, chase and coworkers reported on their implementation into clinical practice and evaluation of the specialized relative insulin nutrition table (sprint). This is an improved protocol in the form of a wheel - based system to control blood glucose levels and nutritional intakes in i... |
Foot and mouth disease (fmd) is one of the highly contagious diseases of domestic animals, caused by foot - and - mouth disease virus (fmdv), a member of the family picornaviridae, which has a colossal global impact, due to the huge number of animals affected . The fmd endemic countries collectively contain three - qua... |
Huntington's disease (hd) is a progressive, autosomal dominantly inherited neurodegenerative disorder, characterized by impaired motor control, cognitive decline, and occasional psychiatric illness . Hd results from the expansion of a cag repeat in exon 1 of the huntingtin (htt) gene, yielding a protein with a polyglut... |
In early december 2013, during the zikv outbreak, a 44-year - old man in tahiti had symptoms of zikv infection: asthenia, low grade fever (temperature from 37.5c to 38c) and arthralgia . Eight weeks later, he described a second episode of symptoms compatible with zikv infection: temperature from 37.5c to 38c, headache ... |
Irritable bowel syndrome (ibs) is a common gastrointestinal disorder affecting approximately 1015% of the people in western world . The patient group is very heterogeneous and characterized by abdominal pain, discomfort and abnormal bowel habits . The pathophysiology of ibs is unknown, it would appear that the due to t... |
Intracranial dural arteriovenous fistula (davf) is abnormal arteriovenous shunts that occur within the leaflets of the dura mater and comprised 10 - 15% of intracranial arteriovenous malformation8). In a meta - analysis of 377 patients with davf reported before 1989, tentorial davf was only 8% (32/ 377) of all intracra... |
Over the last 3 decades, population - based studies aiming to determine the true burden of neurological disorders have increasingly been acknowledged . Nevertheless, in developing countries, the limited access of neurologists to rural areas and the logistic and economic limitations to perform neuroepidemiological studi... |
Group a included patients of arm with ru fistula who had undergone posterior sagittal anorectoplasty (psarp) without closure of ru fistula, from february 2006 to january 2010 . The rest of the psarp procedure was the same as conventionally done, the only difference being that we did not close the ru fistula after separ... |
The pathogenesis of middle ear cholesteatoma has been debated for a century, but there are four basic theories: invagination, basal cell hyperplasia, epithelial ingrowth and squamous metaplasia . During last century, etiopathogenicity of middle ear cholesteatoma raised many controversies and still a unanimous concept d... |
Dynamic biomolecules often undergo large - scale structural changes and visit distinct conformational states during their biological function . It is of great biological and pharmaceutical interest to characterize their structures and conformational transition pathways . Ideally, detailed free energy landscapes are sou... |
A 40-year - old, previously healthy man presented with left hemiparesis and left facial weakness which had developed four hours before admission after being struck on the right side of the neck by the edge of a door . Ct and mri of the brain revealed acute infarction in the vascular territory of the right middle cerebr... |
Allogeneic bone marrow transplantation (bmt) is widely used in the treatment of various hematologic disorders, such as leukemia and aplastic anemia, and the major complication of bmt is graft - versus - host disease (gvhd). We discuss whether autologous melanocyte transplantation is an appropriate way as a treatment of... |
Spondylolisthesis is defined as an anterior migration of a vertebral body in relation to the vertebra located immediately caudal . In 1930 junghanns was the first to describe anterior translation of a lumbar vertebra without any defect in the neural arch following this the term degenerative spondylolisthesis (ds) was i... |
The research protocol was approved by the institutional review board at the oregon health & science university (ohsu) and performed in accordance with the tenets of the declaration of helsinki . Written informed consent was obtained from each participant after explanation of the nature and possible consequences of the ... |
Organic foreign bodies are generally associated with severe inflammatory reaction and infection, while the nature of reaction elicited by inorganic foreign bodies depends on the material of the foreign body . Graphite, which is the major constituent of pencil lead, has been reported to remain inert in the eye for a lon... |
Polyacrylonitrile (pan) are commercially important and used for the precursor for high - performance carbon fiber . In the fiber applications, pan is dissolved in a suitable solvent and spin to fibers by a wet or dry spinning process . The extensively used solvents are aqueous sodium sulfocyanate (nascn), n, ndimethylf... |
Fistulae between the upper respiratory and gastrointestinal tracts are uncommon in adults . Whereas developmental anomaly is the commonest cause in infancy and childhood, the etiology in adults is most frequently secondary to an esophageal malignancy . We report two cases of esophagobronchial fistulae one secondary to ... |
An individual, as a consumer researcher, wants to buy a refrigerator . With appliances of most sorts, people regard best practice decision making as consulting trustworthy comparison websites and magazines, ones that go beyond expressing opinions, or recording likes, to numerically rate the alternative products on a se... |
Pancreatic intraepithelial neoplasia (panin) is a nomenclature for microscopic proliferative epithelial lesions of the pancreas which was proposed in 2001 by hruban et al . . Panin is assumed to be a precursor lesion of invasive ductal carcinoma (idc). Precursor lesions of idc also include intraductal papillary mucinou... |
Ductal adenocarcinoma of the prostate was first reported by melicow and pachter in 1967 as an endometrial carcinoma prostatic utricle . Since then, ductal adenocarcinoma of the prostate has been found to account for 0.27.5% of all prostate carcinomas . A 73-year - old man was referred to our hospital due to an elevated... |
Patients treated with salvage chemotherapy had a response rate of only 9% and a median time to tumor progression (ttp) of 9 weeks . Although bevacizumab can offer a significantly higher response rate of 55% and a period of clinical stabilization with a median ttp of 26 weeks, the tumor remains in the brain and continue... |
Plaque - induced gingivitis is one of the most frequent periodontal diseases, affecting more than 90% of the population, regardless of age, sex or race20 . Brazilian epidemiologic studies show a high prevalence of gingival inflammation, ranging from 74% to 100%, although the mean individual percentage of gingival bleed... |
There have been sporadic cases reported since it was first described by lennox et al ., in 1952 . We report an additional case of pmc of the skin in a 70-year - old male presenting with a swelling in the lateral canthal region of his left eye, and review the pertinent literature . A 70-year - old male noticed a swellin... |
Incidental detection of small renal masses is increasing . This has led to an increase in biopsy of small renal masses, a proportion of which needle biopsy of small renal masses is controversial owing to the risk of seeding malignant cells along the needle tract . Needle tract seeding is a rare event; the incidence is ... |
Despite its ubiquity in cell membranes, there is little quantitative information on the effects of small mole fractions of cholesterol on the phase diagrams, molecular organization, and surface viscosity of mixtures of phospholipids and cholesterol . Understanding cholesterol s effects in altering the local molecular o... |
Pollution is predicated to all tiny particles in the air which are produced due to human or natural activities (1). Since the centralization of human activities is associated with metabolic human interactions in urban areas, different pollutants enter into air easily and cause the urban environment more vulnerable (2).... |
The syndrome is named after french neurosurgeon octave crouzon, who described this rare genetic disorder first time in 1912 . Although it is encountered rarely, crouzon syndrome constitutes almost 5% of all craniosynostoses with an approximate birth prevalance of 1/25,000 - 1/50,000 . The syndrome is characterized by a... |
Permanent postoperative hypoparathyroidism results from the unintentional removal or injury of parathyroid glands during thyroid and parathyroid surgery . Permanent hypoparathyroidism is defined as persistent hypocalcemia requiring calcium and vitamin d supplementation 6 months after surgery . The risk is nominal durin... |
A major feature of the movement toward hospital cost containment in the last decade has been the replacement of expensive inpatient care with less costly outpatient care . Most discussions about the increasing reliance on outpatient care focus on utilization and revenue measures . A more important issue for hospital pa... |
Wilms tumor (wt), also known as nephroblastoma, is the most frequent renal tumor occurring in children aged 0 to 15 years, especially among those younger than 6 years . Wt accounts for roughly 6% of all childhood cancers; 5% of whom had bilateral involvement, and 1% of whom had a family history . Thanks to the prospect... |
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