| --- |
| license: cc-by-4.0 |
| task_categories: |
| - tabular-regression |
| - tabular-classification |
| tags: |
| - gwas |
| - summary-statistics |
| - psychiatric-genomics |
| - pgc |
| - anx |
| - mental-health |
| - genetics |
| - genomics |
| - biology |
| - health |
| - bioinformatics |
| pretty_name: PGC Anxiety Disorder GWAS Summary Statistics |
| size_categories: |
| - 1M-10M |
| configs: |
| - config_name: anx2016 |
| default: true |
| data_files: |
| - split: train |
| path: data/anx2016/*.parquet |
| - config_name: anx2026 |
| data_files: |
| - split: train |
| path: data/anx2026/*.parquet |
| - config_name: anx2026_GADsymptsQuant |
| data_files: |
| - split: train |
| path: data/anx2026_GADsymptsQuant/*.parquet |
| - config_name: panic2019 |
| data_files: |
| - split: train |
| path: data/panic2019/*.parquet |
| language: |
| - en |
| source_datasets: |
| - pgc |
| --- |
| |
| # PGC Anxiety Disorder — GWAS Summary Statistics |
|
|
| [](https://creativecommons.org/licenses/by/4.0/) |
|
|
| ## Dataset Description |
|
|
| Genome-wide association study (GWAS) summary statistics for **Anxiety Disorder** phenotypes from the [Psychiatric Genomics Consortium (PGC)](https://pgc.unc.edu/). |
|
|
| Each publication is available as a separate subset (config) and can be loaded independently. |
|
|
| ## Usage |
|
|
| ```python |
| from datasets import load_dataset |
| |
| # Load a specific GWAS |
| ds = load_dataset("OpenMed/pgc-anxiety", "anx2016") |
| print(ds) |
| ``` |
|
|
| ### List all available subsets |
|
|
| ```python |
| from datasets import get_dataset_config_names |
| print(get_dataset_config_names("OpenMed/pgc-anxiety")) |
| ``` |
|
|
| ## Subsets |
|
|
| | Config | Phenotype | Journal | Year | PubMed | Rows | |
| |--------|-----------|---------|------|--------|------| |
| | `anx2016` | Anxiety Disorders & Factors | Molecular Psychiatry | 2016 | [26754954](https://pubmed.ncbi.nlm.nih.gov/26754954/) | — | |
| | `anx2026` | Anxiety Disorders (Case-Control) | Nature Genetics | 2026 | [39006447](https://pubmed.ncbi.nlm.nih.gov/39006447/) | — | |
| | `anx2026_GADsymptsQuant` | GAD Symptoms (Quantitative) | Nature Human Behaviour | 2026 | Pending | — | |
| | `panic2019` | Panic Disorder | Molecular Psychiatry | 2019 | [31712720](https://pubmed.ncbi.nlm.nih.gov/31712720/) | — | |
|
|
| ## Data Format |
|
|
| All data is stored as **Apache Parquet** shards (10,000 rows each). Common columns: |
|
|
| | Column | Description | |
| |--------|-------------| |
| | `SNP` / `ID` | SNP rsID or variant identifier | |
| | `CHR` | Chromosome | |
| | `BP` / `POS` | Base-pair position (typically GRCh37/hg19) | |
| | `A1` | Effect allele | |
| | `A2` | Non-effect allele | |
| | `OR` / `BETA` | Odds ratio or effect size | |
| | `SE` | Standard error | |
| | `P` | P-value | |
| | `_source_file` | Original source filename | |
|
|
| > Column names vary between publications. Check each subset's schema. |
|
|
| ## Citation |
|
|
| Please cite the original publication (see PubMed links above) and acknowledge the PGC: |
|
|
| > Data were obtained from the Psychiatric Genomics Consortium — https://pgc.unc.edu/ |
|
|
| ## Terms of Use |
|
|
| Released under **[CC BY 4.0](https://creativecommons.org/licenses/by/4.0/)**. |
|
|
| - Cite the original publication(s) |
| - Do not attempt to re-identify individual participants |
| - Comply with the PGC [data use policies](https://pgc.unc.edu/for-researchers/data-access/) |
|
|
| ## Source |
|
|
| - [Psychiatric Genomics Consortium (PGC)](https://pgc.unc.edu/) |
| - [PGC Downloads](https://pgc.unc.edu/for-researchers/download-results/) |
|
|
| --- |
|
|
| *Last updated: April 2026* |
|
|
