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#' Jiayi rewrite Jun 2024 #' CreateVCF #' #' #' Create the VCF (Variant Call Format) file #' @param bamdir The Path of to the BAM Directory #' @param Genome_Fa Path for whole genome FASTQ file #' @param DIR_Genome_DICT #' @param Picard_Path Path to the Picard directory, with all the JAR files #' @param CMD_gatk #' @par...
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plotSingleRun <- function(sigDat, quantDat, boxDat, eventDat, baseDat, TitleDat){ ## fix 0 baased coordinates passed in sigDat$Position <- sigDat$Position + 1 quantDat$Position <- quantDat$Position + 1 boxDat$Position <- boxDat$Position + 1 eventDat$Position <- eventDat$Pos...
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#' Cochrane review: detailed summary of meta-analyses #' #' @description #' Calculate and print a detailed summary of all meta-analyses in a #' Cochrane review. #' #' @aliases summary.rm5 summary.cdir #' #' @param object An object of class \code{rm5} or \code{cdir}. #' @param x An object of class \code{summary.rm5}...
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R
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library(dplyr) library(snow) library(ggplot2) library(ComplexHeatmap) library(RColorBrewer) library(ggrepel) library(ggrastr) library(viridis) library(enrichR) library(future) ######################################## ###Volcano plot DE genes each cluster### ident.de <- function(i) { x <- gsub(".csv...
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--- title: "CPASSOC_SHom" author: "Gokberk Alagoz, L&G Dept., MPI for Psycholinguistics" date: "`r Sys.Date()`" output: rmarkdown::github_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) source("/home/gokala/programs/CPASSOC/FunctionSet.R") library(data.table) library(plyr) library(qqman) ``...
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# fine mapping SNP To target gene using ABC (BIP) # ABC-MAX library(dplyr) library(stringr) library(reshape2) library(rtracklayer) library(ComplexHeatmap) library(circlize) library(data.table) setwd('~/PF_25BR/data/') load('/sc/arion/projects/CommonMind/roussp01a/INGELHEIM/atacseq/step3_neuron_width500/files/abc_pis...
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# Load libraries library(scater) library(Seurat) library(tidyverse) library(cowplot) library(Matrix.utils) library(edgeR) library(dplyr) library(magrittr) library(Matrix) library(purrr) library(reshape2) library(S4Vectors) library(tibble) library(SingleCellExperiment) library(pheatmap) library(apeglm) library(png) libr...
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# Get command line arguments args = commandArgs(trailingOnly=TRUE) file=args[1] sample_name=args[2] fmt=args[3] outdir=args[4] # Load necessary libraries library(tidyverse) library(ggthemes) library(svglite) log_message <- function(message) { cat(sprintf("[%s %s\n]", Sys.time(), message)) } save_plot <- function(p...
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library(dplyr) library(snow) library(ggplot2) library(ComplexHeatmap) library(RColorBrewer) library(ggrepel) library(ggrastr) library(viridis) library(enrichR) library(future) ######################################## ###Volcano plot DE genes each cluster### ident.de <- function(i) { x <- gsub(".csv...
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library(liger) library(Seurat) library("plyr") library(reticulate) np <- import("numpy") Args<-commandArgs() PATHDIR = Args[6] RNAfile = paste0(Args[6],'scRNA_count.txt') rna = read.csv(RNAfile,sep = '\t',header = TRUE,row.names = 1,quote = "") spatial_origal = as.data.frame(t(read.csv(paste0(Args[6],'Insitu_count.txt...
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### EMD to measure KO screen effects - whether each guide has similar effects on changing transcriptome? ### code adopted from https://github.com/yanwu2014/teratoma-analysis-code/blob/fd1be4e669027236e20a7d85e1cccf4d9a0743d2/Figure4/03_disease_screen_cluster_enrich.R library(perturbLM) library(swne) # one command from...
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#' @title Iteractive clustering #' @description Iterative clustering algorithm for single cell RNAseq dataset. #' @param norm.dat data input #' @param select.cells data ref #' @param prefix meta input #' @param k.nn meta input #' @param max.dim meta input #' @param split.size meta input #' @param result meta i...
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###Script 1 #pre-process and QC individual libraries library(SoupX) library(Seurat) library(sctransform) library(dplyr) library(HGNChelper) library(DoubletFinder) parallel::mclapply timestamp() fls <- c("filepath/neuM02_count_res/outs/", "filepath/neuM03_count_res/outs/", "filepath...
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library(dplyr) library(tidyr) library(stringr) library(Seurat) # 1. Data normalizeation and calculation of admixture GBM.data <- Read10X_h5("filtered_feature_bc_matrix.h5") # Initialize the Seurat object with the raw (non-normalized data). GBM_xeno <- CreateSeuratObject(counts = GBM.data, project = "GBM_xenografts", ...
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clean_island= function(vector, island_size){ #reshape grid= embed(vector, island_size+2) #first and last column must be NA ss1= is.na(grid[,1]) & is.na(grid[,island_size+2]) #sum of middle columns must NOT be NA if(island_size==1){ ss2= !is.na(grid[,2]) } else { mc= 2:(island_size+1) s...
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--- title: "Cell type annotation" output: html_document: df_print: paged --- Libraries ```{r Librairies} library(tidyverse) library(dplyr) library(clustree) library(patchwork) library(Seurat, lib.loc = "/opt/rstudio-server_conda/conda/envs/rstudio-server_4.1.0/lib/R/library/") ``` Import objects ```{r Objects}...
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#' @name DEPRECATED-spc.loess #' @concept deprecated #' #' @title (DEPRECATED) #' LOESS smoothing interpolation for spectra #' #' @description #' These \pkg{hyperSpec} functions are **deprecated** and not maintained any #' more. You should not use these. #' Currently they are present due to back-compatibility re...
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# -------------------------------- # Load libraries and data # -------------------------------- library(rstudioapi) library(yaml) library(readr) library(lme4) library(lmerTest) # Set working directory to script location setwd(dirname(rstudioapi::getActiveDocumentContext()$path)) # Load configuration config <- read_ya...
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--- title: "Comparison_ClusteringAlgorithms" author: "Fabienne Rössler" date: '2023-02-15' output: html_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` Required libraries: ```{r, message=FALSE, warning = FALSE} source("DLCAnalyzer_Functions_v4.R") source("UnsupervisedAn...
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# Get command line arguments args = commandArgs(trailingOnly=TRUE) file=args[1] sample_name=args[2] kegg=args[3] fmt=args[4] outdir=args[5] # Load necessary libraries library(tidyverse) library(ggthemes) library(svglite) # Required functions log_message <- function(message) { cat(sprintf("[%s %s\n]", Sys.time(), me...
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test_that("metareg examples run", { data(Fleiss1993cont) Fleiss1993cont$age <- c(55, 65, 55, 65, 55) Fleiss1993cont$region <- c("Europe", "Europe", "Asia", "Asia", "Europe") ma1 <- metacont(n.psyc, mean.psyc, sd.psyc, n.cont, mean.cont, sd.cont, data = Fleiss1993cont, sm = "SMD") ma...
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args <- commandArgs(trailingOnly = T) filenamex=as.character(args[[1]]) include_files <- c("dMDA_101_5Mb_t2t", "Pico_101_250kb_t2t", "Pico_76_250kb_t2t", "PTA_101_500kb_t2t", "PTA_48_500kb_t2t") if ((filenamex %in% include_files)){ turan_CNV1_svd= readRDS(file.path('./data/processed/rds', paste0('CNV1_', filenamex,'.r...
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#' generate_type3_data #' #' This function generates data and plots for selected clusters. #' #' @param meta_data_file Path to the metadata file. #' @param gene_count_file Path to the gene count file. #' @param selected_clusters A named vector specifying the clusters to include. #' @param Prefix Prefix for the output C...
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# File: compute_qNet_CI.R # Author: Kelly Chang # Date: Oct 2017 # Version: 1.0 # # Description: R script to compute credible intervals for qNet and plot # the results for fixed-input and uncertainty-input simulations. # For help, run this script with command lin...
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test_that("RVE methods work in univariate random effects meta-analysis", { data(Fleiss1993bin) data(Fleiss1993cont) data(smoking) mbin <- metabin(d.asp, n.asp, d.plac, n.plac, study, data = Fleiss1993bin, method = "Inverse", method.random.ci = "CR1", random...
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suppressPackageStartupMessages({ library(readxl) library(tidyverse) library(openxlsx) library(tximport) library(DESeq2) library(pheatmap) }) source("script_tximport.R") meta <- read.xlsx("meta_data.xlsx") if (!file.exists("dds.filtered.rds")){ dds.raw <- DESeqDataSetFromTximport(txi, ...
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source('./scripts/01_Setup.R') all2= readRDS("./data/processed/rds/SignificantCells.rds") picocells_passing_mad_conf= all2$id Pico_76 <- readRDS("./data/processed/rds/PTA_48_500kb_lift_SegFixed_cnv_stat_genome.rds") Pico_76x= Pico_76[Pico_76$id%in%picocells_passing_mad_conf,] Pico_76x= Pico_76x[!Pico_76x$chr%in%c('chr...
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library(tidyverse) library(janitor) `%nin%` = negate(`%in%`) setwd('~/Dropbox/Research/UCSF/ABA') # NACC ## Import datasets nacc.raw <- read_csv('resources/investigator_nacc58.csv') ## NACC variables of interest nacc_df_lv <- select(nacc.raw, NACCID, NACCADC, VISITYR, PACKET, NACCVNUM, NACCAGE, ...
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#Set the variables path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/mri/conn_matrix/pvt" beh_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/" save_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/results...
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#' @title DTSERIESvextract #' #' @description Extracts vertex-wise surface-based CIFTI dense time-series data from an individual dtseries .nii file from HCP, fMRIprep or XCP-D preprocessed directories, and stores it as a single .RDS file. #' @details The function extracts the data from the dtseries.nii file provided, a...
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#' data wrangling for phylogenetic annotations with ggtree::geom_facet #' #' @description #' Returns a dataframe for phylogenetic annotations with ggtree::geom_facet #' with options geom_bar, for a categorical variable that is stored in a #' nested table. For nested contingency tables and usage with geom_text and ...
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# loads needed libraries library(tidyverse) library(data.table) library(Seurat) library(WGCNA) set.seed(1234) args = commandArgs(trailingOnly = TRUE) sample_path = args[1] model_path = args[2] pred_path = args[3] threads = as.numeric(args[4]) # get path for other output out_path = dirname(pred_path) #--------------...
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#Set the variables path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/mri/conn_matrix/pvt" beh_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/" save_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/results...
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library(abind) library(glmnet) library(caret) library(waveslim) library(dplyr) # Parse command-line arguments manually args <- commandArgs(trailingOnly = TRUE) # Initialize default values for arguments train_observations <- 80 test_observations <- 10 align <- FALSE # Default to false (no alignment) # Loop through a...
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#Set the variables path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/mri/conn_matrix/nback" beh_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/" save_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/resul...
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#' Cochrane review: trim-and-fill method #' #' @description #' Conduct trim-and-fill analysis for all meta-analyses in a Cochrane #' review. #' #' @aliases trimfill.rm5 trimfill.cdir #' #' @param x An object of class \code{rm5}, \code{trimfill.rm5}, #' \code{cdir} or \code{trimfill.cdir}. #' @param comp.no Compar...
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# based on import example of hyperSpec read.txt.wide and FileIO/read.txt.PerkinElmer.R # you may want to add indices to the hyperSpec obj: # hyobj@data$indices<-spectral.indices(hyobj) read.txt.pz2 <- function ( file = stop("filename is required"), label = list (), wavelength = NULL, short...
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# File: process_boot_results.R # Author: Kelly Chang # Date: Oct 2017 # Version: 1.0 # # Description: R script to do postprocessing of hERG fitting results for # the 12 CiPA training drugs. This script aggregates # bootstrapping results, plots the bootstrap distr...
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#Set the variables path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/mri/conn_matrix/pvt" beh_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/" save_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/results...
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source('./scripts/01_Setup.R') all2= readRDS("./data/processed/rds/SignificantCells.rds") picocells_passing_mad_conf= all2$id Pico_76 <- readRDS("./data/processed/rds/Pico_76_250kb_lift_SegFixed_cnv_stat_genome.rds") Pico_76x= Pico_76[Pico_76$id%in%picocells_passing_mad_conf,] Pico_76x= Pico_76x[!Pico_76x$chr%in%c('c...
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#' Calculate absolute and percentage weights for meta-analysis #' #' @description #' This function returns a data frame containing information on #' absolute and percentage weights of individual studies contributing #' to common effect and random effects meta-analysis. #' #' @param object An object of class \code{met...
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#' Load and attach `hyperSpec` and all installed *R hyperSpec* family (`hySpc.*`) packages #' #' This function loads and attaches **hyperSpec** and all installed #' [*R hyperSpec*](https://r-hyperspec.github.io/) family packages, which #' share common **`hySpc.`_something_** package name pattern. #' #' @param exclude ...
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##---------------------------------------------- ## create PCA plot of 1KG and adc NP subjects ##---------------------------------------------- library(data.table) library(magrittr) library(ggplot2) cargs <- commandArgs(trailingOnly = TRUE) merged_eigenvec_file <- cargs[1] study <- cargs[2] study_ids <- fread(paste0(...
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#Set the variables path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/mri/conn_matrix/nback" beh_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/" save_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/resul...
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#Set the variables path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/mri/conn_matrix/nback" beh_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/" save_path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/resul...
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# Set generic ---------------------------------------------------------------- .rmmvnorm <- function(n, mean, sigma) { if (!requireNamespace("mvtnorm")) { stop("package 'mvtnorm' needed to generate multivariate normal random data.") } .group <- rep.int(seq_along(n), n) ## make indices so that pooled or i...
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## ----------------------------------------------------------------------------- ## ## Somatic variant detection in lesional focal epilepsy ## Variant-level statistics of dNdScv meta-analysis calls versus population ## ## Author: Dr. Christian Bosselmann ## ## Date Created: 2023-09-05 ## ## Copyright (c) Christian Boss...
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###Script _ #Pseudo Bulk DE analysis library(Seurat) library(SingleCellExperiment) library(scater) library(MAST) library(dplyr) library(future) library(future.apply) dt.sct <- readRDS("datasets/5_seurat_neuron_subset.rds") levels(Idents(dt.sct)) calc_mast_DE <- function(i) { print(i) dt.sub <- ...
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#' Create study labels for forest plot #' #' @description #' Create study labels for forest plot. #' #' @details #' This auxiliary function can be used to create study labels in JAMA #' or Lancet layout which can be added to a forest plot using argument #' 'studlab'. #' #' @param object An object of class \code{meta...
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library(tidyverse) #net_cols <- c("#E69F00", "#56B4E9", "#009E73", "#F0E442", "#0072B2", "#D55E00", "#CC79A7") # original order net_cols <- c("#0072B2", "#009E73", "#D55E00", "#56B4E9", "#E69F00", "#F0E442", "#CC79A7") # reordering for 3 colours only plt_in = '/home/mgell/Work/reliability/input/' plt_out = '/hom...
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# Plotting settings ========================================================== # Base plot parameters ------------------------------------------------------- # Note: more knitr settings further down! knitr::knit_hooks$set(small.mar = function(before, options, envir) { if (before) { par(mar = c(4.1, 4.1, 1, .6))...
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--- title: "qscore_analysis" author: "Gokberk Alagoz, L&G Dept., MPI for Psycholinguistics" date: "`r Sys.Date()`" output: rmarkdown::github_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) library(ggplot2) library(data.table) ``` ## Load Genomic SEM output files ```{r loadData} outDir = ...
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#' Create stacked effect size plot #' #' Note that this is a custom function and will not work in a "universal" way #' without additional coding. #' #' @param x a data.frame object #' @param group string. From your data frame, specify the variable to be used to group the plots. #' @param x_axis logical. Defaults to FA...
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library(R.matlab) library(xlsx) library(car) library(readxl) library(zoo) library(lmPerm) library(boot) #set the variables path = "/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnectivity/data/mri/conn_matrix/rs" result_path <- '/m/cs/scratch/networks-pm/effects_externalfactors_on_functionalconnecti...
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library(tidyverse) #net_cols <- c("#E69F00", "#56B4E9", "#009E73", "#F0E442", "#0072B2", "#D55E00", "#CC79A7") # original order net_cols <- c("#0072B2", "#009E73", "#D55E00", "#56B4E9", "#E69F00", "#F0E442", "#CC79A7") # reordering for 3 colours only plt_in = '/home/mgell/Work/reliability/input/' plt_out = '/hom...
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# Attempt to recreate table 3.3 from "Elements of statistical learning" 2nd ed # Written by Jean-Philippe.Vert@mines.org # Modified by Kevin Murphy (12/2/15) #http://cbio.ensmp.fr/~jvert/svn/tutorials/practical/linearregression/linearregression.R #################################### ## Prepare data ################...
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library(data.table) library(ggplot2) library(ggthemes) hs <- fread("output/gwas/mega/saige/hs_saig_results.txt") late <- fread("output/gwas/mega/polmm/late_polmm_results.txt") bell2022 <- fread("/data_global/summary_statistics/GCST90027158_buildGRCh38.tsv.gz") radius <- 2e5L tmem_lead_snp <- hs[CHR == 7][p.value ==...
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# Dependencies ------------------------------------------------------------ packagesCRAN <- c("remotes", "hdf5r", "glue", "R.utils", "Seurat", "parallel", "tidyverse", "BiocManager") package.check <- lapply( packages, FUN = function(x) { if (!require(x, character.only = TRUE)) { ...
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# We have published the information of the union peak set on https://ngdc.cncb.ac.cn/ (BioProject ID is PRJCA015229), and it can be directly accessed. # Step1: liftOver Macaque Peaks (rheMac10) into hg38 system("liftOver ../Macaque_ATAC/Peak_df/ArchR/Count_Peaks.bed rheMac10ToHg38.over.chain.gz Macaque_Peaks_hg38.bed ...
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library(dplyr) library(tidyr) library(treeio) library(ggtree) library(readxl) library(photobiology) library(ggplot2) library(ggnewscale) library(castor) library(ape) with(snakemake@input, { tree_file <<- tree metadata_file <<- metadata }) output_file <- unlist(snakemake@output) to_treedata <- function(tree) ...
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--- title: "Figure5_transfer_RocheData" author: "Fabienne Rössler" date: '2023-06-08' output: html_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` ```{r, message=FALSE, warning = FALSE} source("../DLCAnalyzer_Functions_v4.R") source("../UnsupervisedAnalysis_Functions.R") ...
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# Attempt to recreate table 3.3 from "Elements of statistical learning" 2nd ed # Written by Engin Alper # Modified by Kevin Murphy (12/2/15) # Info on data is here: http://statweb.stanford.edu/~tibs/ElemStatLearn/datasets/prostate.info.txt suppressPackageStartupMessages({ library(cvTools) library(glmnet) librar...
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# Function ------------------------------------------------------------------- .math2 <- function(x, digits) { validObject(x) x[[]] <- callGeneric(x[[]], digits) x } #' Mathematical functions for `hyperSpec` objects #' #' The functions `abs()`, `sign()`, `sqrt()`, `floor()`, `ceiling()`, `trunc()`, #' `round(...
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library(tidyverse) #net_cols <- c("#E69F00", "#56B4E9", "#009E73", "#F0E442", "#0072B2", "#D55E00", "#CC79A7") # original order net_cols <- c("#0072B2", "#009E73", "#D55E00", "#56B4E9", "#E69F00", "#F0E442", "#CC79A7") # reordering for 3 colours only plt_in = '/home/mgell/Work/reliability/input/' plt_out = '/hom...
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library(tidyverse) #net_cols <- c("#E69F00", "#56B4E9", "#009E73", "#F0E442", "#0072B2", "#D55E00", "#CC79A7") # original order net_cols <- c("#0072B2", "#009E73", "#D55E00", "#56B4E9", "#E69F00", "#F0E442", "#CC79A7") # reordering for 3 colours only plt_in = '/home/mgell/Work/reliability/input/' plt_out = '/hom...
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#' Sequence generation along spectra or wavelengths #' #' This function generates sequences along the spectra (rows) or wavelengths of #' `hyperSpec` objects. #' #' Note that [wl2i()] generates sequences of indices along the wavelength axis. #' #' [seq()] had to be implemented as S3 method as the generic has only \dot...
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R
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library(WGCNA) load("BrainGVEx_human_brain_AdjustCombatandCovariants.rdata") load("../tpmoverlapgenes.rdata") datExpr <- AA_datExpr[genes,] # Choose a set of soft-thresholding powers powers = c(c(1:30), seq(from = 20, to=40, by=2)) # Call the network topology analysis function sft = pickSoftThreshold(t(datExpr), pow...
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test_that("transf handles Freeman-Tukey transformed incidence rates", { rate <- c(0.1, 0.2, 0.3) time <- c(10, 20, 30) expected <- 0.5 * (sqrt(rate) + sqrt(rate + 1 / time)) expect_equal(ir2ft(rate, time), expected) expect_equal(transf(rate, "IRFT", time = time), expected) expect_equal(transf(rate, "IRFT...
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--- title: "Causal Balancing" author: "Eric W. Bridgeford" date: "`r Sys.Date()`" output: rmarkdown::html_vignette vignette: > %\VignetteIndexEntry{cb.balancing} %\VignetteEngine{knitr::rmarkdown} %\VignetteEncoding{UTF-8} --- ```{r setup, include = FALSE} knitr::opts_chunk$set( collapse = TRUE, comment = "#...
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library(tidyverse) library(ggExtra) format_cor <- function(test) { p_value <- format(test$p.value, digits = 2, scientific = TRUE) conf_low <- round(test$conf.int[1], 2) conf_high <- round(test$conf.int[2], 2) result <- sprintf("r(%d) = %.2f, p = %s, 95%% CI [%.2f, %.2f]", test$param...
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#============================= # create manhattan plot #============================= plot_manhattan <- function(results, thin=TRUE, annotate_snps=FALSE, annotate_labels=FALSE, highlight=FALSE, ...
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args <- commandArgs(trailingOnly = T) filenamex=as.character(args[[1]]) exclude_files <- c("dMDA_101_5Mb_t2t", "Pico_101_250kb_t2t", "Pico_76_250kb_t2t", "PTA_101_500kb_t2t", "PTA_48_500kb_t2t", 'Pico_76_250kb_t2t_q1','Pico_76_250kb_t2t_q10','Pico_101_250kb_t2t_q1','Pico_101_250kb_t2t_q10', ...
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# Set generic ---------------------------------------------------------------- #' @importFrom lattice latticeParseFormula setGeneric("levelplot", package = "lattice") ###--------------------------------------------------------------------------~ ### levelplot.R - everything that has to do with levelplot-like plottin...
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#Trial with harmonisation #July 2024 library(sva) library(tidyverse) library(psych) #prepare a smaller dataset data_combat <- retest_Boney%>%dplyr::select(OASISID, sROI_bonecortex03, sROI_bonethickness03, sROI_headthickness03, tis_head, tismri_volr01, res1) dat1 <- data_...
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library(tidyverse) library(ggExtra) format_cor <- function(test) { p_value <- format(test$p.value, digits = 2, scientific = TRUE) conf_low <- round(test$conf.int[1], 2) conf_high <- round(test$conf.int[2], 2) result <- sprintf("r(%d) = %.2f, p = %s, 95%% CI [%.2f, %.2f]", test$param...
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read_one= function(ID, path= getwd(), start_filename= "subject-", append_TOBII= "_TOBII_output.tsv", skip= 7, separate_behavioral= TRUE){ #get likely adresses tobii= paste0(path, "\\", start_filename, ID, append_TOBII) ...
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bind_SE_with_NA <- function(platforms, sample_id){ # Set the column names of each platform to the universal sample identifier platforms <- lapply(platforms, function(i) { colnames(i)<-colData(i)[[sample_id]] i} ) # Bind the assay data, order full_assay <- lapply(platforms, function(i) data.frame...
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--- title: "CRS1_LDB_Analysis" author: "Lukas von Ziegler" date: '2024-01-26' output: html_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) ``` ```{r, message=FALSE, warning = FALSE} source("DLCAnalyzer.R") source("BFA_BFF.R") library(sp) #tested with v1.3-2 library...
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## ----------------------------------------------------------------------------- ## ## Somatic variant detection in lesional focal epilepsy ## This script is used to support therapeutic actionability of the targets ## in this study by their number of ongoing trials and drug assocations ## ## Author: Dr. Christian Bosse...
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#' Atlas parcellations of fsaverage5 #' #' A list containing two data frames, 1) listing fsaverage5 vertices and each parcellation number they correspond to, and 2) listing each available atlas and their corresponding labels (1=aparc, 2=Destrieux-148, 3=Glasser-360, 4=Schaefer-100, 5=Schaefer-200, 6=Schaefer-400). #' ...
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library(abind) library(glmnet) library(caret) library(waveslim) library(dplyr) # Parse command-line arguments manually args <- commandArgs(trailingOnly = TRUE) # Initialize default values for arguments train_observations <- 80 test_observations <- 10 align <- FALSE # Default to false (no alignment) # Loop through a...
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# --------------------------------------------------------------------------------- # # # # Hippocampal volumes in UK Biobank are associated with APOE only in older adults # # ...
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###Script 17 #MAST DE analysis library(Seurat) library(SingleCellExperiment) library(scater) library(MAST) library(dplyr) library(future) library(future.apply) ###Pseudo-bulk DE analysis #Get pseudo-bulk expression data dt.raw <- readRDS("output/atlas/non_integrated_neuronal_atlas.rds") dt.sct <- rea...
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#### Initialize ---- # zap() # load libraries library(maplet) library(tidyverse) library(magrittr) library(dplyr) source(codes.makepath("autofocus/Backend_Modules.R")) source(codes.makepath("autofocus/initialize.R")) #source(codes.makepath("autofocus/ModuleTesting.R")) ####ADNI#### get_adni_R<- function(){ # Lo...
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# set thresholds for plotting tile pointMaxReads <- 40 pointMaxBases <- 200 textLim <- 150 plotPerReadStats <- function(StatData, OrdData, baseDat, boxCenter, arePvals){ all_reg_ids <- unique(StatData$Region) last_reg_id <- tail(all_reg_ids, 1) for(reg_i in all_reg_ids){ regDat <- StatData[StatData...
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#=============================================== # Create list of duplicates to remove #=============================================== library(data.table) library(magrittr) library(stringi) related <- fread("tmp/adc_dup.con") setnames(related, c("ID1", "ID2"), c("IID1", "IID2")) related[, PI_HAT := (2 * N_IBS2 + N_I...
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####################################################### ### Deep Brain Stimulation: STN vs GPi. ### Models ### 2023 Katrin Petermann ####################################################### ####################################################### ### Risk Factor Model ###################################################...
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library(Seurat) library(openxlsx) library(SingleCellExperiment) library(tidyverse) library(Matrix) library(scales) library(cowplot) library(RCurl) library(pryr) library(RColorBrewer) library(dplyr) library(textclean) seu <- readRDS("directory/Annotated_seu_obj.rds") MTG <- as.character(seu$MTG_annotation_log_normalis...
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#######Calculation of module preservation load("../ChineseHumanBrain/Chinese-Signed-networkConstruction-auto.RData") load("../BrainGVEx/Caucasian-Unsigned-networkConstruction-auto.RData") load("../overlapgenes.rdata") load("AA-Unsigned-networkConstruction-auto.RData") color <- moduleColors #colorGVX <- GVXinformatio$mo...
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#load 3 matrices. library(Matrix) library(MatrixExtra) library(tidyverse) setwd(dirname(rstudioapi::getActiveDocumentContext()$path)) #they don't have dim names, so we need to attach the cells and genes in proper order for each #before continuing. sathy <- readMM("../raw_data_full/sathyamurthy/matrix_sathy...
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##' An improved version for RRHO, which aims to correct the intepretation for top left region (up in x and down in y) nad bottom right region. ##' ##' We improved the algorithm such that all four regions of RRHO plot are meaningful ##' @title RRHO2 ##' @param RRHO_obj RRHO object. See RRHO2_initialize for details. ##' ...
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library(reshape2) library(ggplot2) library(gridExtra) options(stringsAsFactors = FALSE) args = commandArgs(trailingOnly=TRUE) parsed_file <- args[1] hist_file <- args[2] preseq_out <- args[3] preseq_in <- args[4] fasta_file<-args[5] id_out <- args[6] count.hist<-read.delim(hist_file,header=FALSE) flags<-read.delim(...
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args <- commandArgs(trailingOnly = T) filenamex=as.character(args[[1]]) standardize_name <- function(name) { return(gsub('[^0-9a-zA-Z]+', '_', name))} selectedCells = read.table(file.path('./data/processed/', filenamex, 'analysis'), header=TRUE) delimiters = ".bowtie|.bt2" samp <- readRDS("./data/processed/rds/Sampl...
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library(Seurat) library(ggplot2) library(ggrastr) library(dplyr) library(viridis) dt.sct <- readRDS("output/atlas/integrated_neuronal_atlas.rds") ################## ###Full dataset### dt.umap.integrated <- dt.sct@reductions$umap.harmony@cell.embeddings %>% cbind(dt.sct@meta.data %>% select(Region, harm...
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--- title: "Optic Nerve Combined: Microglia DEG analysis" author: "Katie Emberley, Jonathan Nelson, and Jeremiah Reyes" date: "`r format(Sys.time(), '%d %B, %Y')`" output: html_document: toc: yes toc_depth: 3 toc_float: true number_sections: yes theme: bootstrap df_print: paged code_foldi...
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#' Produce traffic light plot of risk of bias assessment #' #' @description #' Produce traffic light plot of risk of bias assessment #' #' @param object An object of class \code{rob}. #' @param colour Specify colour scheme for the traffic light plot; see #' \code{\link[robvis]{rob_summary}}. #' @param psize Size of...
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#' Evaluate function on wavelengths of `hyperSpec` object #' #' This is useful for generating certain types of baseline "reference spectra". #' #' @param x either `hyperSpec` object or numeric vector. #' @param ... expressions to be evaluated. #' @param normalize.wl function to transform the wavelengths before evaluati...
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#' @title Find differential expressed gene #' @description Find differential expressed gene. #' @param new_data Data input, single cell expression matrix. #' @param data_meta Cell type classification result from RunSubclassClassify. #' @param cell_number Cell type classification result from RunSubclassClassify. #...
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args <- commandArgs(trailingOnly = T) CNVnamesx= as.character(args[[1]]) source('./scripts/01_Setup.R') standardize_name <- function(name) { return(gsub('[^0-9a-zA-Z]+', '_', name))} Confid_MAD_VariableSize_hg38_xlsx <- readRDS(file.path('./data/processed/rds', paste0(CNVnamesx, ".rds"))) delimiters = ".bowtie|.bt...
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--- title: "GWAMA" author: "Gokberk Alagoz, L&G Dept., MPI for Psycholinguistics" date: "`r Sys.Date()`" output: rmarkdown::github_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE) source("https://github.com/baselmans/multivariate_GWAMA/blob/master/Test_Data/N_weighted_GWAMA.function.1_2_6.R?...