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MATLAB
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%----------------------------------------------------------------------- % Job PART 2 % spm SPM - SPM12 (7771) % cfg_basicio BasicIO - Unknown %----------------------------------------------------------------------- %% matlabbatch{1}.spm.tools.dartel.warp.images = { { '/da...
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function varargout = randraw(distribName, distribParams, varargin) % % EFFICIENT RANDOM VARIATES GENERATOR % % See alphabetical list of the supported distributions below (over 50 distributions) % % 1) randraw % presents general help. % 2) randraw( distribName ) % presents help for the specif...
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MATLAB
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function varargout = WheelAnalyzer24chSpike(varargin) % WHEELANALYZER M-file for WheelAnalyzer.fig % WHEELANALYZER, by itself, creates a new WHEELANALYZER or raises the existing % singleton*. % % H = WHEELANALYZER returns the handle to a new WHEELANALYZER or the handle to % the existing single...
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MATLAB
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function varargout = WheelAnalyzer24chSpike(varargin) % WHEELANALYZER M-file for WheelAnalyzer.fig % WHEELANALYZER, by itself, creates a new WHEELANALYZER or raises the existing % singleton*. % % H = WHEELANALYZER returns the handle to a new WHEELANALYZER or the handle to % the existing single...
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MATLAB
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function varargout = WheelAnalyzer24chSpike(varargin) % WHEELANALYZER M-file for WheelAnalyzer.fig % WHEELANALYZER, by itself, creates a new WHEELANALYZER or raises the existing % singleton*. % % H = WHEELANALYZER returns the handle to a new WHEELANALYZER or the handle to % the existing single...
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MATLAB
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function varargout = WheelAnalyzer24chSpike(varargin) % WHEELANALYZER M-file for WheelAnalyzer.fig % WHEELANALYZER, by itself, creates a new WHEELANALYZER or raises the existing % singleton*. % % H = WHEELANALYZER returns the handle to a new WHEELANALYZER or the handle to % the existing single...
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MATLAB
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function varargout = WheelAnalyzer24chSpike(varargin) % WHEELANALYZER M-file for WheelAnalyzer.fig % WHEELANALYZER, by itself, creates a new WHEELANALYZER or raises the existing % singleton*. % % H = WHEELANALYZER returns the handle to a new WHEELANALYZER or the handle to % the existing single...
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MATLAB
204,353
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function varargout = WheelAnalyzer24chSpike(varargin) % WHEELANALYZER M-file for WheelAnalyzer.fig % WHEELANALYZER, by itself, creates a new WHEELANALYZER or raises the existing % singleton*. % % H = WHEELANALYZER returns the handle to a new WHEELANALYZER or the handle to % the existing single...
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MATLAB
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function Repeat5touchLtRt global CCresultRtouchWon CCresultLtouchWon RpegTouchallWon LpegTouchallWon SpikeArrayWon tfile pegpatternname trimFolder2 pegpatternum TouchCountW12345 SpikeFR_5Touch_Bin RLRLRcount LRLRLcount... Spike1FR_5Touch_Bin Spike2FR_5Touch_Bin Spike3FR_5Touch_Bin Spike4FR_5Touch_Bin tTouchCount1...
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NEURON
23
2
load_file("fig6.hoc")
c76338d3e64e523dd8f708415c096c759d322c9eff4e10d381eac902041bf8bc
NEURON
43
2
load_file("_Testing/init_SimManager.hoc")
4cb151095251ba11a3bcefba4c41c18fe239c8be36b5306d25a5b5bf1a985359
NEURON
53
2
load_file("_Testing/init_InsideOutDiffManager.hoc")
5d9b26b536b2721eb15780bfeb5ee6e2b59597e484a1d20770f5629e97adbc13
NEURON
106
6
func myDistFunc() { local x, y x = $1 y = x/10 + 50*sin(2*PI*x/200) * tanh(x/100) return y }
02d5aef8c16f758e8ec24858452e1378541669d2e77e3a629dd426b6c62abf04
NEURON
265
31
TITLE ...just to store peak membrane voltage : M.Migliore June 2001 UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) } NEURON { SUFFIX ds RANGE vmax } ASSIGNED { vmax } INITIAL { vmax=v } BREAKPOINT { if (v>vmax) {vmax=v} }
9b9f0cced027be7ff5daa3fe5e14224599279f98cd235946b575f5e34d99759c
NEURON
277
20
: Voltage gap junstion NEURON { POINT_PROCESS Gap_neuron NONSPECIFIC_CURRENT i RANGE r, i, VoltageGap } PARAMETER { r = 100000(megohm) VoltageGap = -85 (millivolt) } ASSIGNED { v (millivolt) i (nanoamp) } BREAKPOINT { i = (-VoltageGap +v)/r }
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NEURON
308
22
: Voltage gap junstion NEURON { POINT_PROCESS Gap NONSPECIFIC_CURRENT i RANGE r, i, VoltageGap POINTER vgap } PARAMETER { r = 100000(megohm) VoltageGap = -85 (millivolt) } ASSIGNED { v (millivolt) vgap (millivolt) i (nanoamp) } BREAKPOINT { i = (-VoltageGap +v)/r }
c89d89b887d7a43aa74fa739d9c29bc09874508da45935f518302d0d9a3a6195
NEURON
315
29
TITLE the leak current UNITS { (S) = (siemens) (mV) = (millivolt) (mA) = (milliamp) } NEURON { SUFFIX leak NONSPECIFIC_CURRENT i RANGE gmax THREADSAFE } PARAMETER { gmax = 0.0001 (S/cm2) Eleak = -65 (mV) } ASSIGNED { v (mV) i (mA/cm2) } BREAKPOINT { i = gmax*(v-Eleak) }
fc0d3eacd488a8c6046945c929ca97582188788083394303723fb30b79359ab2
NEURON
326
21
TITLE GABA tonic passive membrane channel UNITS { (mV) = (millivolt) (mA) = (milliamp) (S) = (siemens) } NEURON { SUFFIX GABA_tonic NONSPECIFIC_CURRENT i RANGE g, e } PARAMETER { g = 0.000000001 (S/cm2) <0,1e9> e = -59 (mV) } ASSIGNED {v (mV) i (mA/cm2)} BREAKPOINT { i = g*(v...
adb9a5aece5c86795a5af4ab42f69f78c2652785fd3172ac6682f6587d062067
NEURON
360
20
TITLE gaba leak COMMENT If want outward rectification use tonicgaba2 ENDCOMMENT NEURON{ SUFFIX gaba1 NONSPECIFIC_CURRENT i RANGE i, e, gbar } UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { gbar = 0 (siemens/cm2) } ASSIGNED{ v (mV) i (milliamp/cm2) minf e (...
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NEURON
363
23
// Create a soma create soma access soma // Set the geometry of the soma soma { L = 50 // Length in micrometers diam = 50 // Diameter in micrometers } // Define biophysical properties for the soma soma { Ra = 100 // Axial resistance in Ohm*cm cm = 1 // Membrane capacitance in uF/cm^2 ...
b847b6c23b1bafe5a0e1d428ecddc212a8687d87988f899555e3d86c12cf9a5c
NEURON
419
35
: Linear kineticks of potassium pumping. 2018 Savtchenko et al. TITLE kpump NEURON { SUFFIX kpump USEION k READ ki, ko WRITE ik RANGE Kp, Krest } UNITS { (molar) = (1/liter) (mV) = (millivolt) (mM) = (millimolar) (mA) = (milliamp) } PARAMETER { Kp = 0.1 (mA/cm2) Krest = 110 (mM) } ASSIGN...
6771eb034771de86ab5a16ef458b26bb4edd033cbfd98ee11ed48e5c31c129e3
NEURON
442
35
TITLE passive membrane channel with Glu conductance UNITS { (mV) = (millivolt) (mA) = (milliamp) (S) = (siemens) (molar) = (1/liter) (mM) = (millimolar) } NEURON { SUFFIX IKa USEION k READ ki, ko WRITE ik :NONSPECIFIC_CURRENT i RANGE gk } PARAMETER { gk = 0.001 (mS/cm2) <0,1e9> :ki = 120 (mM) <0,...
f352e73a99ed50467a155dfe48e6a46d051b3a2e069fbfd15a06ed0bb293653f
NEURON
606
47
COMMENT Longitudinal diffusion of sodium (no buffering) (equivalent modified euler with standard method and equivalent to diagonalized linear solver with CVODE ) ENDCOMMENT NEURON { SUFFIX nadifl USEION na READ ina WRITE nai RANGE D } UNITS { (mM) = (milli/liter) (um) = (micron) FARADAY = (faraday) (coulomb) P...
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NEURON
622
39
: A simple membrane mechanism just for demo : Can be replaced with any other which "USEION k READ ko WRITE ik" NEURON { SUFFIX iksine USEION k READ ko WRITE ik RANGE ik0, A, x, X, T } UNITS { PI = (pi) (1) } PARAMETER { ik0 (mA/cm2) A (mA/cm2) x (um) X (um) T (ms) } ASSIGNED { ...
8d6659568d09552c6193eebfd26709f7c9ade99b9e1df97900f748245bad75af
NEURON
632
38
:NMODL for Sinusoid IClamp: :Sinusoid current clamp : The code was download from https://www.neuron.yale.edu/phpBB/viewtopic.php?t=1250 NEURON { POINT_PROCESS IClampSin RANGE del, dur, amp, freq, phase, bias ELECTRODE_CURRENT i } UNITS { (nA) = (nanoamp) } PARAMETER { del=100000 (ms) dur...
c946d9e3a7afb306ee8a9db18d1800e4c88e3d7afd57b5d307ace074997d6b95
NEURON
701
55
COMMENT Longitudinal diffusion of potassium (no buffering) Savtchenko et al., 2018 ENDCOMMENT NEURON { SUFFIX kdifl USEION k READ ik, ki WRITE ki RANGE Dk, ki0, iextra } UNITS { (mM) = (milli/liter) (um) = (micron) FARADAY = (faraday) (coulomb) PI = (pi) (1) } INITIAL { ki = ki0 ka = ki } PARAMETER ...
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NEURON
770
48
TITLE inward rectifier potassium (Kir4) channel COMMENT This is kinetics of Kir4.1 channels ENDCOMMENT NEURON { SUFFIX kir4 USEION k READ ko, ek WRITE ik RANGE ik, gkir, NormK } UNITS { (molar) = (1/liter) (mA) = (milliamp) (mV) = (millivolt) (mS) = (millisiemens) (mM) = (m...
b3feb8215e5ba79070d9c6b132660d8449ea6a900999b140ad0cb1ce8b2ae0ca
NEURON
794
43
: calcium flux gap junction. 2018 : 04 01 2018 : Modification of ica NEURON { POINT_PROCESS GapCaExtr USEION ca READ cai WRITE ica RANGE TimeRelex, BasicCa, ExtraCaConcentration, fluxion } UNITS { (molar) = (1/liter) (mM) = (millimolar) (um) = (micron) (mA) = (milliamp) FARADA...
36073ba8b09896ed15a6f3a38d84cfc90b62fdb519293b26f1d53a3ed8e468c2
NEURON
849
60
TITLE sodium potassium pump : from Lindblad et al Am J Physiol 1996 275:H1666 NEURON { SUFFIX NaKpump USEION k READ ko WRITE ik USEION na READ nai WRITE ina RANGE ik, ina , INaKmax, ink, Kmko, Kmnai, ki0, nao0 GLOBAL dummy : prevent vectorization for use with CVODE } UNITS { (mA) = (milliamp) (mV) = (millivol...
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NEURON
850
66
NEURON { POINT_PROCESS IClampNoise RANGE i,del,dur,f0,f1,r,torn,std,bias ELECTRODE_CURRENT i } UNITS { (nA) = (nanoamp) } PARAMETER { del=50 (ms) dur=200 (ms) torn=500 (ms) std=0.2 (nA) f0=0.2 (nA) f1=0.8 (nA) r =60 bias = 0 (nA) } ASSIGNED { ival (nA) i (nA) amp (nA) no...
3136cc2be718c69380bc93b246f08ef974da01c3608e101eb9c04a4af672f0e7
NEURON
892
48
NEURON { POINT_PROCESS Gap45 RANGE GVal, g, i, vgap, Ginf, Gtau GLOBAL Nj, g_main, GMax NONSPECIFIC_CURRENT i THREADSAFE : assigned GLOBALs will be per thread } STATE { G } PARAMETER { Nj = 1000 g_main = 32 (picosiemens) GMax (picosiemens) } INITIAL { GMax = (((32-4.2393)/(1+exp((0-39.55)/10.24)))+4.2393)+...
0e7cd8c5d27c34d44e9b87e0e16ef63c19365f30f408c90f29f9c5df204d7bcc
NEURON
894
25
TITLE gaba leak COMMENT If want ohmic gaba use tonicgaba1 From Pavlov et al., 2009 Outwardly Rectifying Tonically Active GABAA Receptors in Pyramidal Cells Modulate Neuronal Offset, Not Gain ENDCOMMENT NEURON{ SUFFIX gaba2 NONSPECIFIC_CURRENT i RANGE i, e, gbar, minf } UNITS { (mA) = (milliamp) (mV...
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NEURON
900
48
NEURON { POINT_PROCESS Gap43 RANGE GVal, g, i, vgap, Ginf, Gtau GLOBAL Nj, g_main, GMax NONSPECIFIC_CURRENT i THREADSAFE : assigned GLOBALs will be per thread } STATE { G } PARAMETER { Nj = 1000 g_main = 61 (picosiemens) GMax (picosiemens) } INITIAL { GMax = (((61-14.6460)/(1+exp((0-61.41)/8.405)))+14.6460...
823a77f6ceb66f96fb32a230d32dbebd720bcc8c30c9af49258bafae53e51abf
NEURON
913
48
NEURON { POINT_PROCESS Gap40 RANGE GVal, g, i, vgap, Ginf, Gtau GLOBAL Nj, g_main, GMax NONSPECIFIC_CURRENT i THREADSAFE : assigned GLOBALs will be per thread } STATE { G } PARAMETER { Nj = 1000 g_main = 162 (picosiemens) GMax (picosiemens) } INITIAL { GMax = (((162-23.6384)/(1+exp((0-57.74 )/13.42)))+23.6...
d8b379384803cadbabfbbbf51aa32a9c22aca30f3a67cf658980a6a93892877b
NEURON
922
61
TITLE Sodium persistent current for RD Traub, J Neurophysiol 89:909-921, 2003 COMMENT Implemented by Maciej Lazarewicz 2003 (mlazarew@seas.upenn.edu) ENDCOMMENT INDEPENDENT { t FROM 0 TO 1 WITH 1 (ms) } UNITS { (mV) = (millivolt) (mA) = (milliamp) } NEURON { SUFFIX nap USEION na READ ena WRITE ina RANGE...
4d4d8e4025725ab3d7c316dfda95faedc4c444a82dad5fcc54c5c6488dca8acd
NEURON
959
55
TITLE Ampa synapse COMMENT simple alpha-synapse that generates a single PSP ********************************************* reference: McCormick, Wang & Huguenard (1993) Cerebral Cortex 3(5), 387-398 ********************************************* Assembled for MyFirstNEURON by...
560686512e781ed5f8b1cf2809a2014c15746685b888c6255261525cf2a5a0f9
NEURON
962
70
TITLE KCNQ potassium channel for GPe neuron COMMENT modeled by Gunay et al., 2008 implemented in NEURON by Kitano, 2011 ENDCOMMENT UNITS { (mV) = (millivolt) (mA) = (milliamp) } NEURON { SUFFIX kcnq USEION k READ ek WRITE ik RANGE gmax, iKCNQ } PARAMETER { v (mV) dt (ms) gmax = 0.001 (mho/cm2) ikcnq = ...
fd971b053a9a35f20317aefd9ec1fb4078c2fa0de90f8f4b14f322b02e596a35
NEURON
967
56
TITLE decay of submembrane calcium concentration : : Internal calcium concentration due to calcium currents and pump. : Pump action is approximated by a simple first order decay. NEURON { SUFFIX cad USEION ca READ ica, cai WRITE cai RANGE depth,kd,cainf,taur } UNITS { (molar) = (1/liter) : moles do not appear i...
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NEURON
1,026
80
: Vector stream of events NEURON { THREADSAFE ARTIFICIAL_CELL VecStim POINTER ptr } ASSIGNED { index etime (ms) ptr } INITIAL { index = 0 element() if (index > 0) { net_send(etime - t, 1) } } NET_RECEIVE (w) { if (flag == 1) { net_event(t) element() if (index > 0) { net_send(etime - t, 1) ...
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NEURON
1,032
71
: Kv2.1 : from Beining et al (2016), "A novel comprehensive and consistent electrophysiologcal model of dentate granule cells" NEURON { SUFFIX Kv21 USEION k READ ek WRITE ik RANGE gkbar, gk, ik } UNITS { (S) = (siemens) (mV) = (millivolt) (mA) = (milliamp) } PARAMETER { gkbar = 0.00001 (S/cm2) } ASSIGNED { ...
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NEURON
1,034
46
COMMENT calcium accumulation into a volume of area*depth next to the membrane with a decay (time constant tau) to resting level given by the global calcium variable cai0_ca_ion ENDCOMMENT NEURON { SUFFIX gabaacum USEION gaba READ gabao WRITE gabao RANGE depth, tau, gabao...
8d9f3391ebb8c4e50a71c92a7d7415d6599ff6e441db39e6e42fa24cd07da2ad
NEURON
1,042
92
TITLE CA1 KM channel from Mala Shah : M. Migliore June 2006 UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) ek celsius (degC) gbar=.0001 (mho/cm2) vhalfl=-20 (mV) kl=-2 vhalft=-50 (mV) a0t=0.0005 (/ms) zetat=8 (1) gmt=.5 (1) q10...
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NEURON
1,054
49
: calcium flux gap junction. 2018 : 04 01 2018 : Modification of ica NEURON { POINT_PROCESS GapCa NONSPECIFIC_CURRENT icagap USEION ca READ cai WRITE ica RANGE TimeRelex, icagap, ica, BasicCa, fluxion, jd, ControlGap POINTER gapCaP } UNITS { (molar) = (1/liter) (mM) = (millimolar) (um)...
89ee5eb9bcb20e23fe4f67f61f87bb719c61f773a3d442fbc4aa89664300a641
NEURON
1,099
57
COMMENT calcium accumulation into a volume of area*depth next to the membrane with a decay (time constant tau) to resting level given by the global calcium variable cai0_ca_ion Modified to include a resting current (irest) and peak value (cmax) i is a dummy current needed to force a BREAKPOINT ENDCOMMENT NEURON ...
a2585b735783ebb9b5eca0fc8df1e5b586f310f335034d60ec0147da6a52cc60
NEURON
1,134
73
COMMENT :[$URL: https://bbpteam.epfl.ch/svn/analysis/trunk/IonChannel/xmlTomod/CreateMOD.c $] :[$Revision: 1367 $] :[$Date: 2010-03-26 15:17:59 +0200 (Fri, 26 Mar 2010) $] :[$Author: rajnish $] :Comment : :Reference :Expression of a cloned rat brain potassium channel in Xenopus oocytes. Science, 1989, 244, 221-4 ENDCOM...
8dc0e8f7ee9d8a13f217edbb11c535f9d34a861e0af41add3914f4462e247962
NEURON
1,164
91
TITLE I-h channel from Magee 1998 for distal dendrites UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) ehd = -30 (mV) celsius (degC) ghdbar=.0001 (mho/cm2) vhalfl=-81 (mV) kl=-8 vhalft=-75 (mV) a0t=0.011 (/ms) zetat=2.2 (1) ...
a50c6c46366ccddf0a2f2bee6a49dc7f56fff8bda044ef6f912b096b679df87f
NEURON
1,166
91
TITLE I-h channel from Magee 1998 for distal dendrites UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) ehd (mV) celsius (degC) ghdbar=.0001 (mho/cm2) vhalfl=-81 (mV) kl=-8 vhalft=-75 (mV) a0t=0.011 (/ms) zetat=2.2 (1) ...
2b5e20f13647f3d1f2a000f0ad9281e1f41a5ba6a483ba9f76f9da026c7a3a3e
NEURON
1,175
90
TITLE K-D channel : M.Migliore jun 2006 UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) ek (mV) : must be explicitely def. in hoc celsius (degC) gkdbar=.0 (mho/cm2) vhalfn=-33 (mV) a0n=0.005 (/ms) zetan=3 (1) gmn=0.7 (1) nmax=2 (1) q10=1...
4726d1694e736584dcbb96e1577a3fd376f990557231dcefb8c0296ed47c8276
NEURON
1,176
90
TITLE K-D channel : M.Migliore jun 2006 UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) ek (mV) : must be explicitely def. in hoc celsius (degC) gkdbar=.0 (mho/cm2) vhalfn=-65 (mV) a0n=0.005 (/ms) zetan=2 (1) gmn=0.9 (1) nmax=2 (1) q10=1...
c9842cba7436b97a35e56f0690cf5e924c66e93830fb390b0139ed2ae3fa40f6
NEURON
1,197
71
TITLE SK-type calcium activated K channel UNITS { (molar) = (1/liter) (mV) = (millivolt) (mA) = (milliamp) (mM) = (millimolar) } NEURON { SUFFIX sk USEION ca READ cai USEION k READ ek WRITE ik RANGE gbar, ik, I } PARAMETER { gbar = 0.0 (mho/cm2) q = 1 } ASSIGNED { v (mV) ...
b06c0a3dc2c4418bd547979658ebf98a8e9d55b0765a87d1b3409c7236bd5908
NEURON
1,228
91
TITLE K-DR channel : from Klee Ficker and Heinemann : modified to account for Dax et al. : M.Migliore 1997 UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) ek (mV) : must be explicitely def. in hoc celsius (degC) gkdrbar=.003 (mho/cm2) vhalfn=5 (mV) a0n=0.006 (/...
3fe90a22d9c9a6c1164d8fe7601d044c63312f92f0801200aa642cac23559caa
NEURON
1,250
92
TITLE K-DR channel : from Klee Ficker and Heinemann : modified to account for Dax et al. : M.Migliore 1997 UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) ek (mV) : must be explicitely def. in hoc celsius (degC) gkdrbar=.003 (mho/cm2) vhalfn=13 (mV) a0n=0.02 (/...
83f8c5ff9bb4e4b4103225b9ab6005aaeeeab469d39c8f2b167704aa33f90a56
NEURON
1,290
59
TITLE Calcium dynamics for L and T calcium pool NEURON { SUFFIX caldyn USEION cal READ ical, cali WRITE cali VALENCE 2 RANGE pump, cainf, taur, drive } UNITS { (molar) = (1/liter) (mM) = (millimolar) (um) = (micron) (mA) = (milliamp) (msM) = (ms mM) FARADAY = (faraday) (coulomb) }...
b342347d02f06b6baf3b083190ccc0650c48adb5a499e162dc31ca3f00028b43
NEURON
1,397
92
TITLE I-h channel from Magee 1998 for distal dendrites : default values are for dendrites and low Na : plus leakage, M.Migliore Mar 2010 UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) ehd (mV) celsius (degC) ghdbar=.0001 (mho/cm2) vhalfl=-90 (mV) vhal...
74d789bc77ec2c8608c6df9cc00423e986684ad4ff7c2912b32f64f6d35b19c2
NEURON
1,402
88
TITLE CaGk : Calcium activated K channel. : Modified from Moczydlowski and Latorre (1983) J. Gen. Physiol. 82 UNITS { (molar) = (1/liter) } UNITS { (mV) = (millivolt) (mA) = (milliamp) (mM) = (millimolar) } NEURON { SUFFIX cagk USEION ca READ cai USEION k READ ek WRITE ik RANGE gbar,gkca,ik GLOBAL oinf, ta...
0d842eb8776599a232d3166b668108131f6a25f5897b32049acb42867d290433
NEURON
1,417
71
: Ca local fluxe. 2018, Savtchenko et al., NEURON { POINT_PROCESS GapCaSt NONSPECIFIC_CURRENT icagap USEION ca READ cai WRITE ica RANGE r, icagap, ica, tau1, tau2, ECa, period, amplit } UNITS { (molar) = (1/liter) (mM) = (millimolar) (um) = (micron) (mA) = (milliamp) FARADAY = (fa...
0a6bdd1c308617fdf4ee7575d6d2e4d905d96a1ec8a3c90e23ca9c556259b796
NEURON
1,482
53
// Create soma create soma access soma // Set the geometry of the soma soma { L = 10 // Length in micrometers diam = 10 // Diameter in micrometers } // Create processes create dendrite1, dendrite2, dendrite3, dendrite4, dendrite5 // Set the geometry of the processes proc set_process_geometry() { nseg...
350389170f771bceb6f1716f8df54c10524b7f5ae557e68124fc2b9602884873
NEURON
1,577
79
: Ca channels (N-type) from Aradi and Holmes 1999, transferred from GENESIS to NEURON : increased inactivation time constant and corrected calcium handling by Beining et al (2016), "A novel comprehensive and consistent electrophysiologcal model of dentate granule cells" NEURON { SUFFIX Cav22 USEION ca READ eca WRI...
049aabe7ff8f7e34d7f568b87086f49c5821ccb996ea29a1b7357b893ef09bd4
NEURON
1,629
56
NEURON { SUFFIX GAT1_current GLOBAL Temperature USEION gaba READ gabai, gabao WRITE igaba VALENCE 0 RANGE Egat, conductance NONSPECIFIC_CURRENT iGAT :add to local membrane current but not affecting particular ion conc. : Na+ and Cl- read live from ion pools each timestep. : READ only -- electrogenic charge alr...
fb1e12d9c8acf4394ca826d22a70fb579f47e852558ad7de567c0776d08ddd6b
NEURON
1,638
62
: GluUptake.mod : : Linear glutamate uptake mechanism for BrainCell. : Savtchenko / Rusakov Lab, UCL. : : Simple passive uptake driven by the difference between : the local extracellular glutamate concentration (gluo) and : a baseline resting concentration (gluobasic). : : Formula: : iglu = gluconductance * (gluo - g...
432a7228757d501a3a8b324ae65e527994c150122ca1cdd4564644f1783cb2cc
NEURON
1,685
65
: GABA_tonic_gabao.mod : GABA tonic receptor - conductance gated by extracellular GABA concentration : : The steady-state conductance follows a Hill equation in gabao (mM): : : g = g_max * gabao^n_Hill / (EC50^n_Hill + gabao^n_Hill) : : This captures the nonlinear occupancy of extrasynaptic GABA-A receptors : (delta-...
3a2db66e78816134cc0f2383ecd362d0f945231067e9540d5455088f9008dcc2
NEURON
1,703
118
TITLE l-calcium channel : l-type calcium channel UNITS { (mA) = (milliamp) (mV) = (millivolt) FARADAY = 96520 (coul) R = 8.3134 (joule/degC) KTOMV = .0853 (mV/degC) } PARAMETER { v (mV) celsius (degC) gcalbar=.003 (mho/cm2) ki=.001 (mM) cai = 50.e-6 (mM) cao = 2 (mM) q10 = 5 mmin=0.2 tfa = 1 a0m =0....
9977bfbaf0b5032b08f8fc5d9d056205d370d7c1ae172e7a141456ec514a5737
NEURON
1,726
93
TITLE kdrglia : Kalium delayed rectifier (AHP) : twee gates met elk twee toestanden : : uit: Traub et al. : A branching dendritic model of a rodent CA3 : pyramidal neurone. : Mechanism was donwloaded from https://senselab.med.yale.edu/modeldb/showmodel.cshtml?model=113446&file=/neuron-2008b/kdrglia.mod#tabs-2 UNITS {...
8515996877be666bbfb9839f16e167ae1d93d34375b6376698b1b45a2aa63e5d
NEURON
1,812
70
// Create a soma create soma access soma // Set the geometry of the soma soma { L = 20 // Length in micrometers diam = 20 // Diameter in micrometers insert hh // Insert Hodgkin-Huxley channels } // Create a dendrite create dend access dend // Set the geometry of the dendrite dend { nseg = 5 // Nu...
aaff5fb2fd617adda6009112e62be539421803e0744ae0f68d65f374b7c4a95b
NEURON
1,824
111
: CA1 pyramidal neuron to study INaP properties and repetitive firing (Uebachs et al. 2010) : The file was downloaded from https://senselab.med.yale.edu/ModelDB/showmodel.cshtml?model=125152 UNITS { (mA) = (milliamp) (mV) = (millivolt) (molar) = (1/liter) (mM) = (millimolar) F = 96485 (coul) ...
12c4e722062204197225306ea2a47254bb637a89edb9845afac5266f26335124
NEURON
1,847
82
: model from Evans et al 2013, transferred from GENESIS to NEURON by Beining et al (2016), "A novel comprehensive and consistent electrophysiologcal model of dentate granule cells" : also added Calcium dependent inactivation NEURON { SUFFIX Cav12 USEION ca READ cai, eca WRITE ica :,cai,cao...., cai, cao USEION lc...
a1dc0722b7a3d449de0feb53fec397b33854064a60b0d2a8714255e5206cc53f
NEURON
1,852
101
TITLE nax : Na current for axon. No slow inact. : M.Migliore Jul. 1997 : added sh to account for higher threshold M.Migliore, Apr.2002 NEURON { SUFFIX nax USEION na READ ena WRITE ina RANGE gbar, sh GLOBAL minf, hinf, mtau, htau,thinf, qinf } PARAMETER { sh = 8 (mV) gbar = 0.010 (mho/cm2) tha ...
7b91b81c6316e86bcae94256f4f42dd750ba4a23fa21d3d6b2b19678a4927cc4
NEURON
1,880
121
TITLE K-A channel from Klee Ficker and Heinemann : modified to account for Dax A Current --- M.Migliore Jun 1997 : modified to be used with cvode M.Migliore 2001 UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { v (mV) celsius (degC) gkabar=.008 (mho/cm2) vhalfn=16 (mV) vhalfl=-51 ...
468cdc3b825e09c4c3b76e4400fdad221e46b9c5480f2a777e057592c3388b8c
NEURON
1,890
58
COMMENT This artificial cell plays 2 roles: 1. It implements the release probability mechanics. 2. It informs HOC code about synaptic events. To use it, we replace this chain: NetCon -> Target PP with longer one: NetCon -> SynEventsFilterWatcher -> NetCon -> Target PP (The ...
afc8a04a4abc479c1debe2e9fd8f0b6a555f2ba9df63e9a434cc9b4eae7afd8c
NEURON
1,897
83
: model from Evans et al 2013, transferred from GENESIS to NEURON by Beining et al (2016), "A novel comprehensive and consistent electrophysiologcal model of dentate granule cells" : also added Calcium dependent inactivation NEURON { SUFFIX Cav13 USEION ca READ cai, eca WRITE ica :,cai,cao...., cai, cao USEION lc...
2b725c4cda9b95944ab5fdc039c6adca8b28ab19bf2e2b499f4ecd414b74d6bd
NEURON
1,898
101
TITLE Inwardly rectifying potassium current COMMENT neuromodulation is added as functions: modulation = 1 + damod*(maxMod-1)*level where: damod [0]: is a switch for turning modulation on or off {1/0} maxMod [1]: is the maximum modulation for this specific channel (read from the param file) ...
176de966116dffbfdf0e151acc24388ae7b1a1ccd32b281a818c5cae940f00b1
NEURON
1,904
107
TITLE K-A channel from Klee Ficker and Heinemann : modified to account for Dax A Current ---------- : M.Migliore Jun 1997 UNITS { (mA) = (milliamp) (mV) = (millivolt) } PARAMETER { celsius v (mV) gkabar=.008 (mho/cm2) vhalfn=4 (mV) vhalfl=-51 (mV) a0l=0.05 ...
87aa514c1264e72c23d34e46e661e4572bd32ea9262353eb1269d680ba1b00dd
NEURON
1,914
129
TITLE T-calcium channel : T-type calcium channel UNITS { (mA) = (milliamp) (mV) = (millivolt) (molar) = (1/liter) (mM) = (millimolar) FARADAY = 96520 (coul) R = 8.3134 (joule/degC) KTOMV = .0853 (mV/degC) } PARAMETER { v (mV) celsius = 25 (degC) gcatbar=.003 (mho/cm2) cai = 50.e-6 (mM) cao = 2 (mM) q10...
8caae01c9bcb9d2981b687969e007f5d5658914ebbaab554d5e5be05ebbee1c5
NEURON
1,947
100
COMMENT Mechanism taken from Doron et al., 2017 https://senselab.med.yale.edu/ModelDB/ShowModel.cshtml?model=231427&file=/reproduction/Im.mod#tabs-2 Reference : Adams et al. 1982 - M-currents and other potassium currents in bullfrog sympathetic neurones corrected rates using q10 = 2.3, target temperature 34, orgi...
1af9fb97a4643df627851cce0bde36cb62b3ea4509765192cd8631fe4570de95
NEURON
2,097
111
TITLE Slow A-type potassium current (Kv1.2) COMMENT neuromodulation is added as functions: modulation = 1 + damod*(maxMod-1)*level where: damod [0]: is a switch for turning modulation on or off {1/0} maxMod [1]: is the maximum modulation for this specific channel (read from the param file) ...
e3f11aa5fca91f63616791da69acbdd3ed28efa05cf9b312335cacd26ad0a31b
NEURON
2,098
137
TITLE n-calcium channel : n-type calcium channel UNITS { (mA) = (milliamp) (mV) = (millivolt) FARADAY = 96520 (coul) R = 8.3134 (joule/degC) KTOMV = .0853 (mV/degC) } PARAMETER { v (mV) celsius (degC) gcanbar=.0003 (mho/cm2) ki=.001 (mM) cai=50.e-6 (mM) cao = 2 (mM) q10=5 mmin = 0.2 hmin = 3 a0m =...
c2b5450d074df218f6888de65698a4ae649372ffc205d1ce1af8b250cc411a16
NEURON
2,156
69
: Calcium buffer shell model with instant Calcium handling for clustered channels by Beining et al (2016), "A novel comprehensive and consistent electrophysiologcal model of dentate granule cells" NEURON { SUFFIX Cabuffer USEION ca READ ica,cai,cao WRITE cai, cao USEION nca READ inca WRITE ncai VALENCE 0 USEION lc...
9af129ed3483d7cb11437fca1688a46f2bf8f5a0ddf4aeaae8f7d77d991d9ddc
NEURON
2,166
104
TITLE T-type calcium channel (Cav3.3) UNITS { (mV) = (millivolt) (mA) = (milliamp) (S) = (siemens) (molar) = (1/liter) (mM) = (millimolar) FARADAY = (faraday) (coulomb) R = (k-mole) (joule/degC) } NEURON { SUFFIX cav33 USEION cal READ cali, calo WRITE ical VALENCE 2 RANGE pbar,...
266efbaa9b84669ab378492ac5933da576d03ce956eea3a818a5c9f89752aa17
NEURON
2,233
90
COMMENT i to flux converter This helper membrane mechanism is used in Python as following: node.include_flux(segm._ref_kflux_i2fc) NEURON RxD docs: https://nrn.readthedocs.io/en/latest/python/modelspec/programmatic/rxd.html#rxd.node.Node.include_flux Notice t...
dcc0178f3bb6776c98180b2d9ec90dea9b1f86d21e0af35e42fd920377507edc
NEURON
2,249
103
TITLE T-type calcium channel (Cav3.2) UNITS { (mV) = (millivolt) (mA) = (milliamp) (S) = (siemens) (molar) = (1/liter) (mM) = (millimolar) FARADAY = (faraday) (coulomb) R = (k-mole) (joule/degC) } NEURON { SUFFIX cav32 USEION cal READ cali, calo WRITE ical VALENCE 2 RANGE pbar,...
eee83ec5c3d7a92e4a24330a86738af6384475207b58b98e23c4a81f35d0b044
NEURON
2,343
79
: GluSrc.mod : : Glutamate source mechanism for BrainCell. : Savtchenko / Rusakov Lab, UCL. : : Generates iglu (mA/cm2) as a train of alpha-function pulses. : _InsideOutDiffHelper.mod reads iglu and converts it to gluo via Faraday's law. : : Alpha function for each pulse: : iglu(t) = amplitude * ((t - t_pulse) / tau)...
43bea76b465f4a782b96642c3d6179cc444f963e8291154af9f111013dfdf02c
NEURON
2,419
89
TITLE inward rectifier potassium (Kir) channel COMMENT Mod File by A. Hanuschkin <AH, 2011> for: Yim MY, Hanuschkin A, Wolfart J (2015) Hippocampus 25:297-308. http://onlinelibrary.wiley.com/doi/10.1002/hipo.22373/abstract Channel description and parameters from: Stegen M, Kirchheim F, Hanuschkin A, Staszewski O, Ve...
22336a46447b58c7fb33e2d59d5df86a8e5b249fa2ab545f2f43659804f5b4b9
NEURON
2,435
127
COMMENT Updated Exp2Syn synapse including a modulation function. Defaul values of parameters (time constants etc) set to match synaptic channels in striatal medium spiny neurons, following Wolf et al., 2007 -> Galaretta 1997 modulation = 1 + damod*( (maxMod-1)*level + (max2-1)*lev2 ) two substrates can modulate...
fb4bbc7ad21c5ae3c38d5894919d3a3a05b35546dd9a7ff99454d55ed05cefd4
NEURON
2,435
95
: the dynamics mechanism of the FRAP is developed by Savchenko and others. 2018 NEURON { SUFFIX FRAP USEION frapion READ frapiono, frapioni, ifrapion WRITE frapioni VALENCE 1 GLOBAL vol, Buffer0 RANGE frapion0, Alpha } DEFINE NANN 4 UNITS { (molar) = (1/liter) (mM) = (millimolar) (um) =...
7252a2de075663c536d99e7b9083857e7895021363d1edaa17c9bc8fcee6ebfc
NEURON
2,633
132
TITLE na3 : Na current : modified from Jeff Magee. M.Migliore may97 : added sh to account for higher threshold M.Migliore, Apr.2002 NEURON { SUFFIX na3 USEION na READ ena WRITE ina RANGE gbar, ar, sh GLOBAL minf, hinf, mtau, htau, sinf, taus,qinf, thinf } PARAMETER { sh = 8 (mV) gbar = 0.010 (mho/cm2) ...
85572ecba4c6d231545f7763961600ecd101dbcc52b25de25efbf0dca0b15417
NEURON
2,694
114
TITLE Kv4.2 with auxilliary subunits COMMENT This is the model of Barghaan et al. 2008: Role of N-terminal domain and accessory subunits in controlling deactivation-inactivation coupling of Kv4.2 channels.. Biophysical Journal : implemented by M.Beining; Beining et al (2016), "A novel comprehensive and consistent elec...
f8da3c82437e793c9db5de99be0cadcc5695a9e6968db5adfc44e9df1a565603
NEURON
2,696
124
TITLE Fast A-type potassium current (Kv4.2) COMMENT neuromodulation is added as in two ways: 1. A shift parameter is added to the infinity curves that can be used to shift the voltage dependece of the channel. By deafult this does not also shift the time constant. 2. A function that scales the conductance of the ...
6d0f3107ae2792c9e47255f0089071c753cf820b3778ecd9a6e4877503d815d6
NEURON
2,855
84
// ============================================================ // Cell 1 Geometry — Presynaptic Neuron // Soma : sphere approximated by 8 cylindrical sections (s1_0..s1_7) // laid out along X from 0 to 8*R1/Deformation // diameter profile: 2*R1*cos(theta) gives spherical cross-section // Dend : secti...
2adeab809f71b1bf8f1359db6be5130cd47c879a9948b3f88c9f77afae5742a3
NEURON
2,861
99
TITLE Kv14.mod - modified potassium channels COMMENT This is a Hodgkin-Huxley model of inactivating K channels modified from hh.mod P. Jonas, 12 September 2001 temperature dependence is given up - Q10 scaling is not used any longer Reference: Hines and Carnevale, Expanding NEURON's repertoire of mechanisms with NM...
1fc3ed5db236702ffb6875cf91e6ca7105835d2c9f9b9f0bdc7e8b925f7df9ab
NEURON
2,865
83
// ============================================================ // Cell 3 Geometry — Astrocyte template (reusable) // Soma : sphere approximated by 8 cylindrical sections (s3_0..s3_7) // laid out along X from 0 to 8*R3/Deformation, at Y = CY3 // diameter profile: 2*R3*cos(theta) gives spherical cross-s...
5fc70a049495aea34068c0ec069bbe815442815adc1839a0554774c0950a01ed
NEURON
2,887
136
: M conductance : from Mateos-Aparicio et al (2014) NEURON { SUFFIX Kv723 USEION k READ ek WRITE ik RANGE gkbar, ik, minf, tau1, tau2, i, gk, m1, m2, tadjtau GLOBAL Vhalf, Vshift, k, v0erev, kV, gamma GLOBAL Dtaumult1, Dtaumult2, tau0mult, taudiv, q10tau } UNITS { (mA) = (milliamp) (mV) = (millivolt) (S) = (s...
2cb7adb8e4a1381d5e130294bdc9e9ca5161196fe3bd30d6c7401c21c5fbc7e7
NEURON
3,017
85
// ============================================================ // Cell 2 Geometry — Postsynaptic Neuron // Soma : sphere approximated by 8 cylindrical sections (s2_0..s2_7) // laid out along X from CX2 to CX2 + 8*R2/Deformation // diameter profile: 2*R2*cos(theta) gives spherical cross-section // Dend...
19455b1118be8449ff13ddbf9fdc1d7d1e8f3dcec56c170c16dc19627e236d32
NEURON
3,113
116
TITLE Juxtaparanodal Potassium Channels for CNS Axons : Based on McIntyre et al. 2002 and Devaux et al. 2002 : References in Oozeer 2006 for CNS myelinated fibers : Two types of K channels in juxtaparanodal regions: : 1. DTX-I sensitive (Kv1.1/1.2 family) : 2. KTX sensitive channels : These are located in the juxtapara...
363d7ed34403c78c672e18ae8304de32d0fb4feb7436a42a04f0e678590dcbdb
NEURON
3,139
136
: $Id: netstim.mod,v 1.1.1.1 2001/01/01 20:30:37 hines Exp $ : modified in such a way that the first event will never be before start : M.Migliore Dec.2001 NEURON { POINT_PROCESS NetStimm RANGE y RANGE interval, number, start RANGE noise } PARAMETER { interval = 10 (ms) <1e-9,1e9>: time between spikes (msec...
e1c69b2a73b9a823d3db2b99cf1f3bfe12bd6d03d692bd5528696a30a919aa94
NEURON
3,218
160
TITLE HH style channels for spiking retinal ganglion cells : : Modified from Fohlmeister et al, 1990, Brain Res 510, 343-345 : by TJ Velte March 17, 1995 : must be used with calcium pump mechanism, i.e. capump.mod : : INDEPENDENT {t FROM 0 TO 1 WITH 1 (ms)} NEURON { SUFFIX spike USEION na READ ena WRITE ina USEION...
7adc7810decfc1f2e6bd53f44905b35b1664fb74cf079c6560053c2e14227683
NEURON
3,221
138
COMMENT Noise current characterized by gaussian distribution with mean mean and standerd deviation stdev. Borrows from NetStim's code so it can be linked with an external instance of the Random class in order to generate output that is independent of other instances of InGau. User specifies the time at which the n...
b3db862bd1bf9d38ff1fc387e3a6bfc33794d291f22ec38d0bb0f11345ccd789
NEURON
3,231
134
TITLE Fast transient sodium current COMMENT neuromodulation is added as functions: modulation = 1 + damod*(maxMod-1)*level where: damod [0]: is a switch for turning modulation on or off {1/0} maxMod [1]: is the maximum modulation for this specific channel (read from the param file) ...
05eaff047e0c856f30d03a506dac0e9986f246a4463cb44786f236c39137b713
NEURON
3,352
129
TITLE hh.mod squid sodium, potassium, and leak channels COMMENT This is the original Hodgkin-Huxley treatment for the set of sodium, potassium, and leakage channels found in the squid giant axon membrane. ("A quantitative description of membrane current and its application conduction and excitation in nerv...
02023559efbc196ce9dd2c2c0e591f1808dbdcc6baf5fbfdd13d07f010245e0b
NEURON
3,477
141
COMMENT The model of Glutamate transporter. is based on two papers, from the paper 1. Zhang Z1, Tao Z, Gameiro A, Barcelona S, Braams S, Rauen T, Grewer C. Transport direction determines the kinetics of substrate transport by the glutamate transporter EAAC1. Proc Natl Acad Sci U S A. 2007 Nov 13;104(46):18025-30...
66b1de3446a8fdabd46b7b6f21e17b2f45a9ef333c64b24f9b87770f99a58a1b
NEURON
3,512
122
TITLE Kir potassium current COMMENT Kir 2.1 (Mg high-affinity) model from Beining et al (2016), "A novel comprehensive and consistent electrophysiologcal model of dentate granule cells" based on Yan & Ishihara (2005): Two Kir2.1 channel populations with different sensitivities to Mg(2+) and polyamine block: a model ...