sha256
stringlengths
64
64
language
stringclasses
28 values
size
int32
1
491k
lines
int32
1
23.2k
content
stringlengths
1
200k
c5bf36d371253e05b11f6e8afba150108345d4023cfa424deb36d32c694686b2
R
1,048
52
#the shared script library, where all kinships are declared source('./kinships.R') #the common stats file with number of filtered SNPs for each dataset #stats_infile = '~/Documents/deep_learning_for_breeding/datasets/filtering_stats.csv' #actual elaboration config config = NULL #------- ADDITIVE config = rbind(c...
ef23bad0f3e6e7ddd0f8b6b33e8b19917c1cef8188946b948ca1153ddd4b8532
R
1,067
34
library(LSD) getvals <- function(dir, pattern, filter){ files = list.files(path=dir, pattern=paste0('^',pattern), full.names=T, recursive=T) files = files[grep(filter, files)] say(files) table <- as.data.frame(do.call("rbind", lapply(files, FUN=function(file){ vals=readme(file,skip=95,header=T,gz...
72fe9a2b4a4eda98526cb9723f8015d596dad58e907b018f31e9c00436b3f460
R
1,105
25
test_that("heatmap raw data and rendering tolerate undefined clustering", { grDevices::pdf(NULL); on.exit(grDevices::dev.off(), add = TRUE) x <- .m61_fp3() one <- x; one@result <- one@result[1, , drop = FALSE] flat <- x; flat@result$Pvalue <- rep(0.02, 3) cases <- list(list(one, one), list(x), list(flat, flat...
20f70badd856dffb7147700185671afb274f745b8d8fded5a5d8abd672a9d7b0
R
1,111
34
#' List Current Available Trained Keras Models #' #' @return A `tibble` containing summary models. #' @export #' #' @examples #' list_trained_models() list_trained_models <- function() { ext_path <- system.file("extdata", package = "sigminer.prediction") if (!dir.exists(ext_path)) { ext_path <- system.file("ins...
7081e9e6e88a0f5d6e5e449ebc3c863c16fc8ee967011eb04fca112990b8d354
R
1,130
32
# Contains <ggplot> themes for float_contrast == TRUE | FALSE # # Contains themes `float_contrast_theme` and `non_float_contrast_theme`. # Theme for left-right graph float_contrast_theme <- ggplot2::theme( plot.margin = ggplot2::unit(c(0, 0, 0, 0), "pt"), axis.line.x = ggplot2::element_blank(), axis.title.x = gg...
63b511f627c32c0025aa21557998e476821331e5534a4120c6859c385a06def2
R
1,148
31
source(here("runMonteCarlo.R")) for (section in unique(quant_cluster$Section_Type)){ quant_cluster %>% filter(Section_Type==section) -> dat for (k in unique(quant_cluster$Cluster)){ concat_counts <- runMonteCarlo(dat,k,1000) limits <- apply(concat_counts,1,apply_quantile) actual_count <- rep(0...
f7d7ba526679ba6e77c7a37944558bea26c6c54e5249334418a2d24823de9ae2
R
1,151
33
#' triQP #' #' #' @name triQP #' #' @param df dataset extracted from a QPath analysis and where annotation correspond to "Genotype Sex" #' @description will create 2 columns containing respectively the genotype and the sex of the samples #' #' @examples #' #' #' @export triQP <- function(df) { df$genoty...
57785f1299a4fd81f672f25e9bccbd3b1821ede70406cb04b5050383705a55aa
R
1,156
30
######## options(future.globals.maxSize= 891289600000) rm(list = ls()) if(T){ library(dplyr) library(Seurat) library(patchwork) library(stringr) library(ggplot2) library(tidyverse) } ##加载包 setwd("/public-supool/home/zhchen/XS/2_preproccess") load("/public-supool/home/zhchen/Lab_share/public_source/cellcyc...
37268ae91f050e11a0731d1d638c5d7b3c6ba781644e6df0df635e692c66d98d
R
1,158
78
# Load Packages ## Load Packages into environment library(ggplot2) library(tidyverse) library(readxl) library(openxlsx) # library(xlsx) library(plyr) library(dplyr) library(ggrepel) library(grid) library(gridExtra) library(reshape2) library(grid) library(devtools) library(RColorBrewer) library(ggfortify) library(veg...
0e3e4749a3e77b926916146fffe24d3f3aa7856451ce47e4343a65e25a1e3c90
R
1,167
33
# dat - dataset to subset from (e.g., pooled anterior sections) # k - cluster number for which we are calculating enrichment # n - number of simulations # Subdivisions: list of strings of the names of subdivisions assessed for this current A-P axis position runMonteCarlo <- function(dat,k,n){ dat %>% filter(Cluste...
a4babbb335d69768e7c42fcbc875db2c898ba6dfab9549b24949a82f6f8ef96d
R
1,203
44
a=read.table('TAG.txt',sep='\t',header=T) b=read.table('../../Tasic_exp_sc_mat_cluster_original.txt',header=T,sep='\t') c=read.table('../../Tasic_exp_sc_mat_cluster_merged.txt',sep='\t',header=T) library('cidr') library('NMI') a[,2]=as.character(a[,2]) a[which(a[,2]=='Myelinating.Oligodendrocytes'),2]='Oligodendrocyt...
71a9ad138ec1b4c85a495dc848dd93480c6ec81f83ba45afcc7cc47ed08a62b0
R
1,215
55
--- title: "Slide-seq v2 hippocampus" author: "Will Townes" output: html_document --- ```{r} library(Seurat) library(SeuratData) #remotes::install_github("satijalab/seurat-data") library(SeuratDisk) #remotes::install_github("mojaveazure/seurat-disk") library(scry) #bioconductor fp<-file.path pth<-"scrna/sshippo" dpth...
a00909863a16368a7acec98683a1d6441f96523d7e50fbef75d9db94d7594c42
R
1,219
52
library(imputeR) #half lives, simple seq features, & codon freqs a=readme("seqFeatWithKmerFreqs.txt.gz",gzip=T) a=a[,1:10] dim(a) say("RIP/m6aCLIP") b=readme("allRIPCLIPdata.txt.gz",gzip=T) a=merge(a, b, by=1, all.x=T) dim(a) say("ENCORI") load("peakMatENCORI.RData") colnames(b)[2:ncol(b)]=paste0("ENCORI.",colnames(...
93cabd793ee0f2c998f383b1cd8dea9c99a2abef8840dce62af34738e700e959
R
1,232
45
library('mclust') library('NMI') a=read.table('TAG.txt',header=T,sep='\t') b=read.table('../../Zeisel_exp_sc_mat_cluster_original.txt',header=T,sep='\t') c=read.table('../../Zeisel_exp_sc_mat_cluster_merged.txt',sep='\t',header=T) a[,2]=as.character(a[,2]) a[which(a[,2]=='Myelinating.Oligodendrocytes'),2]...
ade55af2b4b6391b3d89a1d6ea92d031fc0032459ca9a1c9d7cc229015c45bc4
R
1,232
43
library('mclust') library('NMI') a=read.table('Kendall.txt',header=T,sep='\t') b=read.table('../../Zeisel_exp_sc_mat_cluster_original.txt',header=T,sep='\t') c=read.table('../../Zeisel_exp_sc_mat_cluster_merged.txt',sep='\t',header=T) a[,2]=as.character(a[,2]) a[which(a[,2]=='Myelinating.Oligodendrocytes'),2]...
c2014e049d6d3f62b55fb586db7d6b21fbba69747807c7c07dbd6b249f573a72
R
1,239
45
library('mclust') library('NMI') a=read.table('TAG.txt',header=T,sep='\t') b=read.table('../../Habib_exp_sc_mat_cluster_original.txt',header=T,sep='\t') c=read.table('../../Habib_exp_sc_mat_cluster_merged.txt',sep='\t',header=T) a[,2]=as.character(a[,2]) a[which(a[,2]=='Myelinating.Oligodendrocytes'),2]='...
75e698941d684f13a85615da489cb96d2b2e2ba6e6806d7a655607154c5ea0a3
R
1,240
44
a=read.table('TAG.txt',sep='\t',header=T) b=read.table('../../Hochgerner_exp_sc_mat_cluster_original.txt',header=T,sep='\t') c=read.table('../../Hochgerner_exp_sc_mat_cluster_merged.txt',sep='\t',header=T) library('cidr') library('NMI') a[,2]=as.character(a[,2]) a[which(a[,2]=='Myelinating.Oligodendrocytes'),2]='Ol...
635c27fcb5063ea6e3df6528c154e92f31b993d351fd4901e1f3b39d144fb8d9
R
1,248
45
library('mclust') library('NMI') a=read.table('TAG.txt',header=T,sep='\t') b=read.table('../../Hochgerner_exp_sc_mat_cluster_original.txt',header=T,sep='\t') c=read.table('../../Hochgerner_exp_sc_mat_cluster_merged.txt',sep='\t',header=T) a[,2]=as.character(a[,2]) a[which(a[,2]=='Myelinating.Oligodendrocy...
3f676845ac2c0d423204caf2f2d7b61dfd8783b805c415cf4449b1f97dbd101f
R
1,251
45
library('mclust') library('NMI') a=read.table('TAG.txt',header=T,sep='\t') b=read.table('../../Tasic_exp_sc_mat_cluster_original.txt',header=T,sep='\t') c=read.table('../../Tasic_exp_sc_mat_cluster_merged.txt',sep='\t',header=T) a[,2]=as.character(a[,2]) a[which(a[,2]=='Myelinating.Oligodendrocytes'),2]='...
16beff905f77ea38812ef0cc9771f4c217521d94f137b47ee91366fb67026454
R
1,276
40
## BART: Bayesian Additive Regression Trees ## Copyright (C) 2017 Robert McCulloch and Rodney Sparapani ## This program is free software; you can redistribute it and/or modify ## it under the terms of the GNU General Public License as published by ## the Free Software Foundation; either version 2 of the License, or #...
223222a36737abf6a90ef1532a98f6ba31f06f526ba49735af063c653eb5364e
R
1,287
29
### dataPath = "/Volumes/KausaliaHD/AllProjects/BRAIN DATA/MIBI/MIBIData Matlab/May_June2019/HiResScans_uci2717J/DeepCellDataAnalysis/" outputFolder = paste0(dataPath,"/Pooled") dir.create(outputFolder, showWarnings= F, recursive = T) all_data_modMore <- read.csv("/Volumes/KausaliaHD/AllProjects/BRAIN DATA/MIBI/MIBIDa...
c23f454978024e9c6016c65dd97626528405780af103850dda33c532293cc35c
R
1,290
83
## Configure enviornment #### Install CRAN Packages install.packages( c( "ggplot2", "tidyverse", "readxl", "plyr", "dplyr", "ggrepel", "gridExtra", "reshape2", "devtools", "RColorBrewer", "ggfortify", "vegan", "MASS", "compositions", "zCompositions", "g...
655dc9958848a72b48bb83be4b3640073e6784085f8d9ed057af540bef431e12
R
1,292
35
# Install kpcalg + its CRAN dependencies that are not already on conda. # Run AFTER creating the conda env with environment.yml: # conda env create -f environment.yml # conda activate timeawarepc # Rscript install_r_deps.R # # graph, RBGL, and pcalg are already installed by the conda env. options(repos = c(CRAN ...
d1794d4368b961db26c26f471e9788122698620bdeb667aedeab454a168b2113
R
1,297
44
library(Seurat) library(patchwork) library(dplyr) library(DoubletFinder) rm(list = ls()) Tbx3_merge <- readRDS("/public-supool/home/zhchen/XS/3_cluster/Tbx3_merge_0911.rds") if(T){ library(DoubletFinder) sweep.res.list_kidney <- c() sweep.stats_kidney <- c() bcmvn_kidney <- c() mpK <- c() annotation...
886825b65ac166de027b4d744546388fe87ab50b86318852223aaebcca13c68c
R
1,315
45
#' Normalise and scale counts matrix #' #' This function is called by the \code{preprocess} function and performs #' log-normalisation and scaling of a counts matrix. #' #' @param x a matrix of counts #' @param lib.size the library size #' @param log logical, indicates whether the output should be on the log2 scale ...
41e1a3047d5673aacfb1668f5aa8e9a76476bb430280e85f6c74f229b8ff9f3e
R
1,322
36
mrd <- function(input, scales=6, family='db2', output='waveletoutput', scale.of.interest = 3, energy.trace=0, coherency=0, orientation=0, max=0, min=0, maskoriginal=FALSE, out.SOI.only=FALSE) { file <- as.character(input)[1] family <- as.character(family)[1] outputfile <- as.character(output)[1] scales...
43720368225789c96841a26df694a6eef67aea087bfcf51b9acdf236bc2766c5
R
1,323
25
##### Documentation for plots library(ggplot2) fn <- "/Users/dblyon/Downloads/Output/Deamidation.txt" fn_plot <- gsub("txt$", "pdf", fn) df <- read.csv(fn, sep="\t", header = TRUE) df <- df[with(df, order(mean)), ] df$sort_order <- seq(nrow(df)) df$Raw.File <- factor(df$Raw.File, levels=unique(df$Raw.File[df$sort_orde...
f597f5bfefc7a41a7f223cbd5fa415523e422b3a63e7355342c811ebab95fe49
R
1,333
48
#' Compute the cosine similarity #' #' @description Compute the cosine similarity between the columns of #' a matrix or two matrices. #' #' @param x1 (matrix) A numeric matrix #' @param x2 (matrix) A numeric matrix #' #' @return (matrix) A matrix containing the cosine similarity between #' the columns of m1 (and m2) ...
e6c77d40fbce9fbaddb78bfd9721d84f19155c2f8c073d16e6be45a5f4cab091
R
1,338
50
exp_data=read.table('exp_mat.txt',sep='\t',row.names=1,header=F) meta_data=read.table('meta.txt',sep='\t',header=T) library(pcaPP) ################################################################ Stage=meta_data[,9] OUT=c() i=1 while(i<=length(exp_data[,1])){ this_gene=rownames(exp_data)[i] this_exp=t(exp_data[i,]) ...
aabd8ee348e18352a0d7160a3bcab62ebdd3642ebbb5339f845ef72094410836
R
1,353
41
# Test cases describe("Testing plot_delta function", { test_that("Returns a list with correct components for valid inputs", { # Test case: Valid inputs np_dataset <- generate_non_proportional_dataset() dabest_effectsize_obj <- dabestr::load( data = np_dataset, x = Group, y = Measurement, idx = list(...
dec71e208661c3ed1885dd664fff10b1c484a92d8cf92d0fa721bf719793af23
R
1,354
40
batch_binding_annotation <- function() { data.frame( GeneID = LETTERS[1:6], Annot = rep(c("T1", "T2", "T3"), each = 2), Term = rep(c("Term one", "Term two", "Term three"), each = 2) ) } test_that("batchEnrich binds differing columns from real native ORA results", { annot <- batch_binding_annotation()...
548578fae4dc5fabd78c324f032ffd4741a70ed2b8216e65b4c189549264b687
R
1,383
49
#' Generate example data #' #' @return a dataframe containing cell-level information for sample, group and #' clusters #' #' @export #' #' @examples #' #' speckle_example_data() #' speckle_example_data <- function(){ # Make up some data with two groups, two biological replicates in each # group and three cell t...
c0579448410aca6c64f6acccee0b5dbf92891f7e535c938d0f43e2b72579600e
R
1,390
31
# Load data source(here::here("code","01_load_data.R")) # Create long dataset to plot FBC_over_time_long <- PWAWM %>% dplyr::select("patient", "FBC_acute_AF_L", "FBC_acute_AF_R", "FBC_acute_IFOF_L", "FBC_acute_IFOF_R", "FBC_subacute_AF_L", "FBC_subacute_AF_R", "FBC_subacute_IFOF_L", "FBC_...
d2ae9c7f1eda7384aa9d89ba6e80dbccd55702bfb0db7d6ab43ed53cf8746e10
R
1,400
43
## BART: Bayesian Additive Regression Trees ## Copyright (C) 2017-2018 Robert McCulloch and Rodney Sparapani ## This program is free software; you can redistribute it and/or modify ## it under the terms of the GNU General Public License as published by ## the Free Software Foundation; either version 2 of the License,...
2f0fc96e91a2067a9b861869ad3a44bf5bfdad430a27e136f68ba433845649ed
R
1,404
34
# Test cases describe("Testing print_each_comparism function", { test_that("Prints each comparison correctly for valid inputs", { # Test case: Valid inputs with list dabest_obj dd_dataset <- generate_deltadelta_dataset() dabest_obj <- dabestr::load(dd_dataset, x = Genotype, y = Measurement, de...
67f8faacf0cf7068f85904da65e9724427648817adf26fc33d943bac32585c38
R
1,415
40
test_that(context("Test GSEA"), { library(liger) data("org.Hs.GO2Symbol.list") universe <- unique(unlist(org.Hs.GO2Symbol.list)) # get universe gs <- org.Hs.GO2Symbol.list[[1]] # get a gene set vals <- rnorm(length(universe), 0, 10) # simulate values names(vals) <- universe vals[gs] <- rnorm(length(g...
b87d4efa1d65ff9e07f105dd912cfc13d54c545a68b58d0be87f6ad35391d301
R
1,423
30
## CANOES SPARK cnv_espresso_transmission_analysis_file<- './cnv_info_w_img_tranmission_analysis_pilot_prediction.csv' cnv_espresso_df = read.csv(cnv_espresso_transmission_analysis_file) familyID_list <- unique(cnv_espresso_df$FamID) print(paste("Number of family/trio:", length(familyID_list))) transmission_rate_per_...
460fd163f6db1790b687cb8378ec6519be3e1d7d44db9efc4405b2a42812e7fa
R
1,428
45
library(imputeR) #half lives, simple seq features, & codon freqs a=readme("seqFeatWithKmerFreqs.txt.gz", gzip=T) a=a[,c(1,grep("Codon",colnames(a)),grep("3UTR",colnames(a)))] dim(a) b=readme("CWCS.txt.gz",gzip=T) colnames(b)[2:ncol(b)]=paste0("MIR.",colnames(b)[2:ncol(b)]) b[2:ncol(b)] = -1*b[2:ncol(b)] a=merge(a,b,b...
0b80b6dd23f8e80a543991f12341a0761b972fdd160bf624346d577ffdb8a23d
R
1,431
56
--- title: "Import alevin counts & generate Seurat object" date: 'Compiled: `r format(Sys.Date(), "%B %d, %Y")`' output: github_document: html_preview: true toc: true toc_depth: 3 fig_width: 16 html_document: df_print: kable theme: united fig_height: 5 fig_width: 16 out_height: ...
d4c51f4d5400905364a1422038add8356fcd82fd67c499b7354b6802149e0457
R
1,453
43
#Packages suppressPackageStartupMessages(library(tidyverse)) #Output directory outdir='data/isocortex/' #Create outdir if needed if (!dir.exists(outdir)) { dir.create(outdir, recursive = TRUE, showWarnings = FALSE) } #Input and output mouse files infile <- 'data/MouseExpressionMatrix_voxel_coronal_maskcoronal_log2...
91a523f70a2d0f6e1b9a25fa750d56b19c036c7d3b13a92748e66fe845668b66
R
1,456
47
library('Seurat') exp_mat=read.table('GSE92332_atlas_UMIcounts_reheader.txt',sep='\t',header=T,row.names=1) pbmc <- CreateSeuratObject(raw.data = exp_mat, min.cells = 0, min.genes = 0, project = "10X_PBMC") tag=cbind(as.character(pbmc@meta.data$orig.ident),as.character(pbmc@meta.data$orig.ident)) source('scRef.R') NewR...
2d7e4fb370deadeb80a80eeb0cb3380a061048b368e56a8b8f6dbfab187b2ad9
R
1,458
58
--- title: "Data Exploration with the UCSC Cell Browser" date: 'Compiled: `r format(Sys.Date(), "%B %d, %Y")`' output: github_document: html_preview: false toc: false html_document: df_print: kable theme: united --- This vignette demonstrates how to run launch a UCSC Cell Browser instance popula...
08e4494f3ad64bb683f686b02e6e0af6d86c10db8681bd698d130c6d38fa7194
R
1,463
32
### ### Find the unique sample types in the TCGA cancer types available in MEXPRESS. ### The idea is to assign a unique color to each sample type (for consistency ### accross figures), but because there are more than 12 possible sample types ### and I only have 12 unique distinguishable colors to assign, I want to find...
3e676fe4c8a036396e2e91156e8ac4ab6a1f4a4aa3e073e2933f61f868273992
R
1,468
41
setwd("C:\\Users\\zhenjiang fan\\Documents\\workspace\\Pythonworkspace\\Feature selection using deep learning\\data simulation\\RANK") source('isee_all.R') # load packages library(MASS) library(Matrix) p = 40 n=2000 iterAll = 20; dataDir = paste("/ihome/hpark/zhf16/causalDeepVASE/data/simulated_data/",...
c0a09d67e72c6938e9a74593f6760b4d815f2f316e28b7a6158622f2de4e0446
R
1,474
53
library(rhdf5) library(ggplot2) file = args[1] getvals <- function(dir, pattern, filter){ files = list.files(path=dir, pattern=pattern, full.names=T, recursive=T) files = files[grep(filter, files)] table <- as.data.frame(do.call("rbind", lapply(files, FUN=function(file){ if (grepl("preds", file)) { vals = t(h...
c02e625e3a99eda8c2ba79a00c798b807aecb7c513302c8ae95901a3f5dac661
R
1,518
47
library(Seurat) exp_raw_data=read.table('MGH54_mat.txt',sep='\t',header=T,row.names=1) pbmc <- CreateSeuratObject(raw.data = exp_raw_data, min.cells = 3, min.genes = 200, project = "10X_PBMC") pbmc <- NormalizeData(object = pbmc, normalization.method = "LogNormalize", scale.factor = 10000) pbmc <- FindVariableG...
69acf8a1e9d37f299910343250a271e5d420e3c0e5ebe8a9acbf36d8b1510d5a
R
1,532
58
setwd("/home/yanglu/Downloads/RANK/") source('/home/yanglu/Downloads/RANK/gknockoff_all.R') source('/home/yanglu/Downloads/RANK/isee_all.R') # load packages require(graphics) library(igraph) library(MASS) library(Matrix) library(pracma) regfactor = "log" npermu = 5 sis.use = 0 bia.cor = 0 xURL = "...
290663f6688a91dd0332d64ed4abbd024868b25afa78fe038998aaead24ef866
R
1,547
58
library(data.table) library(Biostrings) library(reshape2) kmerlen = 7 file1 = "all_HLs_human_featTable.txt.gz" #replace with "all_HLs_mouse_featTable.txt.gz" for mouse inp.tbl <- fread(paste("zcat", file1),header=T,data.table=F,sep="\t") rownames(inp.tbl) = inp.tbl[,1] inp.tbl[,1] = NULL #get codon frequencies inp....
4c9331c757f0e8ccebd7512c5e2b461c1e03a2033e49c1b4559776d01f751d18
R
1,580
67
load('TSNE.RData') library(Seurat) .addclust <-function(TAG, TSNE_VEC, MINC=3, MAXC=5, random_seed=123456){ random_seed=random_seed TSNE_VEC=TSNE_VEC TAG=as.matrix(TAG) TAG[,1]=as.character(TAG[,1]) TAG[,2]=as.character(TAG[,2]) library(factoextra) set.seed(random_seed) MAXC=MAXC...
1fb75443e63a12cfb88a593e048ae56cdd1ef5f6d8f04f2f9dec9e21fb931e97
R
1,583
45
#Natverse code to display and work with synapse and desmosomal connectors separately #Gaspar Jekely, Sept 2021 library(natverse) # catmaid connection source("~/R/conn.R") #read in dorsal MUSlong cells with connectors MUSlong = nlapply(read.neurons.catmaid("^ventrolateral muscle$", pid=11, ...
915a27ab1093b95e78debd922b07dd4f5e12be4774e70aa4e8d991faca17c020
R
1,607
59
####This script is intended to perform a PCA in order to reduce the dimensionality of cytokines ####in order to predict outcome of covid-19 patients ##data cleveland <- read.csv("~/Documents/covid/COVID_AI/irish/covid_non_covid_all.csv") cleveland <- na.omit(cleveland) ##pca pca <- prcomp(cleveland[, 2:30], scale =...
ad9248cfa4398d9738644f0035271e14deac874f88b99e4ea5969c70c7d16c5b
R
1,615
52
#Install R environment if using conda: #conda install -c r r #Load the R files. Use "\\" on Windows and "/" on Linux gknockoff_all_path = paste(normalizePath(dirname("gknockoff_all.R")),"/DL/knockoff/RANK/", "gknockoff_all.R", sep = "") source(gknockoff_all_path) #source('/ihome/hpark/zhf16/test/DeepPINK/knockoff/RANK/...
022c9c0d23ddafc121705c119f477d58c2cf1cbeb0c11b423cf98d78dcbe77e0
R
1,616
62
library(ggplot2) library(tidyverse) setwd(dirname(rstudioapi::getActiveDocumentContext()$path)) figPath = "figures/" ############################################ # Fig 1B - Gene essentiality ############################################ # load data # fns = c("data/geneEss_model1.txt", # "data/geneEss_newal...
2377f6494186586561548d24f649cb30d6b9be417405c7f0f1d8401e1255ce9c
R
1,644
78
a=read.table('Spearman.txt',sep='\t',header=T) b=read.table('../../Zeisel_exp_sc_mat_cluster_original.txt',header=T,sep='\t') c=read.table('../../Zeisel_exp_sc_mat_cluster_merged.txt',sep='\t',header=T) a[,2]=as.character(a[,2]) a[which(a[,2]=='Myelinating.Oligodendrocytes'),2]='Oligodendrocytes' a[which(a[,2]=='Newly...
68ac53d458ef47b8ccdca47d6832dba9c482b35f85a619f8c172ac784f175766
R
1,670
61
# Functions that generate main_plots based on the main_plot_type of `create_rawplot_components`. # # Contains function `plot_slopegraph`. # Function that plots slopegraph # TODO add proper documentation plot_slopegraph <- function(dabest_effectsize_obj, plot_kwargs) { check_effectsize_object(dabest_effectsize_obj)...
48eb659fe26fde65dd5e82a70dda7821c41df658c6f942a4a89bfac6b3eaceaf
R
1,677
43
##############################Optimal Experimental Design######################### Amination install.packages("AlgDesign") library(AlgDesign) cand <- gen.factorial(levels=c(3,22,3,4), nVars= 4, factors="all", varNames = c("aryl_halide", ...
ad165a1c79c6f42f0ca2ff6f9609d675caac647cf8cd5acecf7cba41393ff573
R
1,681
64
#' Comp2Moy #' #' #' @name Comp2Moy #' #' @param Measure1 a measure from a dataset #' @param Measure2 the same measure from a different dataset #' #' @description Compare 2 dataset using the right test according to normality and variances #' @import rstatix #' @import stats #' #' @examples #' #' Comp2Mo...
e6ec4c417eccf61c99543b491d6388c2702922c48ecf7351c497e1a050f86b49
R
1,697
36
## data-raw/pathway.R -- rebuild data/pathway.rda (object `pathway`). ## ## NOT run as part of richR 0.2.0 M1: the bundled snapshot in data/ is left ## byte-identical. Running this script replaces data/pathway.rda with a fresh ## KEGG snapshot, so run it only when the annotation refresh is intended. ## The date the cur...
e1dbe90ffae838b0004c85eed1b4f3d520bbd87b94f4d72d2a87f71a8fc63d0a
R
1,704
88
# @DESCRIPTION: filename # Library ----------------------------------------------------------------- library(magrittr) library(ggplot2) library(patchwork) library(rlang) # Load data --------------------------------------------------------------- a <- list.files("analysis/2021-11-05/raw", pattern = "All.xls", full...
4af88110c386e0c792afc530b980b427b0a064038eb089624548071645f8f515
R
1,711
51
# Plot Select Features of interest source("src/load_packages.R") source("src/load_phyloseq_obj.R") source("src/Metadata_prep_funcs.R") source("src/miscellaneous_funcs.R") source("src/Community_Composition_Funcs.R") #-----------------------------------------------------------------------------------------------------...
2e5115544078f4f8319d5cf67b8bc4e610158efa89b7fe868cc3cf19c4b106aa
R
1,722
54
setwd("/public-supool/home/zhchen/XS/3_cluster") options(future.globals.maxSize= 891289600000) rm(list = ls()) if(T){ library(dplyr) library(Seurat) library(patchwork) library(stringr) library(ggplot2) library(tidyverse) } ##load package Tbx3_merge <- readRDS("/public-supool/home/zhchen/XS/2_preproccess/T...
2534b8d5ac3443f7a0430089d2fd3ae1e0739fde6396e1e2d36c400385dfb34a
R
1,732
50
library(devtools) library(RColorBrewer) library(plyr) source_url("https://raw.githubusercontent.com/obigriffith/biostar-tutorials/master/Heatmaps/heatmap.3.R") c = readme("all_HLs_mouse.txt.gz", gzip=T) c$external_gene_name=NULL code=as.factor(unlist(lapply(strsplit(colnames(c[,2:ncol(c)]),"\\_"),function(x) x[1])))...
c9f0ec86df28659bcaede9ab4ecbf072d632d57d86fc2c6c3727284b90ca0ec1
R
1,756
59
#http://dropviz.org/ anno=readRDS('annotation.BrainCellAtlas_Saunders_version_2018.04.01.RDS') exp=readRDS('metacells.BrainCellAtlas_Saunders_version_2018.04.01.RDS') COL=which(anno[,1]=='CB') out=exp[,COL] colnames(out)= anno[COL,5] write.table(out, file='GRCm38.81.P60Cerebellum_ALT_mouse.txt', quote=F, sep='\t',ro...
b436ae1a28b44fb777180a82700a9029199f555b6f0aa5a9044cf314ad8ba091
R
1,765
61
rm(list = ls()) source("src/load_packages.R") source("src/miscellaneous_funcs.R") source("src/load_phyloseq_obj.R") source("src/metadata_prep_funcs.R") source("src/community_composition_funcs.R") #---------------------------------------------- # Plot Seq Depth Distributions by group #---------------------------------...
21480f28e908784d013d6dedb52875d38a472530e125ba87e50c91d1147c848a
R
1,785
63
--- title: "Whole-brain comparison of rodent and human brains using spatial transcriptomics" subtitle: "Gene enrichment analysis" author: "Antoine Beauchamp" date: 'August 2nd, 2022' output: html_document --- ```{r setup, include=FALSE} knitr::opts_chunk$set(echo = TRUE, include = FALSE, ...
3163504147a1fbd5064034b68854b85ebd31e3b816405ffa0fc0d16cbe35551d
R
1,796
53
#Plots the DSAVE score for all tissues library(tidyverse) library(DSAVE) fig__dir = "D:/SingleCellModeling/MetAtlas/Figures/" library(Matrix.utils) #for transpose of sparse matrix dsBulk = DSAVE::bulkTotalVar1vs1[[4]] [[2]] dsaveRes = readRDS("D:/SingleCellModeling/MetAtlas/DSAVEData.RDS") tissClust3 = readRDS("D:/...
cc8ffd025d1fcef785b322af25545bfb266ac869c2cb30b3bbb18b8eb46864fd
R
1,796
50
#' Estimate parameters of a Beta distribution from counts #' #' This function estimates the two parameters of the Beta distribution, alpha #' and beta for each cell type. The input is a matrix of cell type counts, #' where the rows are the cell types/clusters and the columns are the samples. #' #' This function is c...
4ab1b2dc76fea5db6a38e1c5c66e01619ed79878a775e80500dfcce12175b388
R
1,800
46
#Shelli Kesler 12/2/16 #Determines fit of degree distribution with power law #Compares fit between two groups #Assumes degree data are listed per subject per region and are in adjacent columns #NOTE: Attach dataframe before running #See https://cran.r-project.org/web/packages/poweRlaw/vignettes/b_powerlaw_examples.pdf...
14224b453948831cfcfcf67b65793bf0600564639bcde37bac187cf2f04098c2
R
1,811
39
# Load data source(here::here("code","01_load_data.R")) # Create long dataset to plot datafr <- PWAWM %>% dplyr::select("patient", "ScreeLing_1_fon", "ScreeLing_1_sem", "ScreeLing_2_fon", "ScreeLing_2_sem", "ScreeLing_3_fon", "ScreeLing_3_sem") %>% pivot_longer(cols = !patient, names_to...
4a8a1e74b998bc73feef71a9b00de5638511b0c69a10ff2f2117ba739361e438
R
1,816
33
# Regenerates plot_reference_m6base.rds (SPEC-RICHR-006 AC-009, REQ-006). # # The reference holds the plot data, layer data and titles of every plot of # set P (richBar, richDot, richNetplot, richNetwork, richNetmap, richLollipop, # richCircle, richNES, richScatter, richECDF, richTermSim, richGeneDot, # richGeneHeat, r...
baf31366ca0b6bbccdd2c6b30a772d9593e0544815478b27a86c580ac9afec40
R
1,817
54
library(glmnet) #mouse model tested w/ human data load("../Robj/BC3MS_CV-Lasso.Robj") #half lives, kmer kreqs, & codon freqs features a=readme("seqFeatWithKmerFreqs.txt.gz",gzip=T) a=a[,c(1:10,grep("Codon",colnames(a)),grep("3UTR",colnames(a)))] #augment matrix w/ mouse miRs -- set to 0 since they don't exist in hum...
5901290cd50e1c99b7ca1d6f5bd5ec7420c66d9138f98c990c6ac62088522a0a
R
1,836
47
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'fdc' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(metr...
6cddce1c12e77832816854837845a5b83c79ec6395f0f2de6898de5abbf11d72
R
1,841
48
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'fd' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(metri...
bc56b15f720372f900e247bb28c15009c4cdc11cc0cde5ecd825e4fb8c3de8e1
R
1,855
48
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'fdc' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(metr...
a9a3c5ba6578577f55129f71633afa0d3bfc9ee595752679980414686ca25947
R
1,861
48
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'fa_DKI' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(m...
bda831afb986f4af06c3a054764fd037cd9f98b4396dd33aad20990b6bd94192
R
1,861
48
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'mk_DKI' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(m...
e143647be2b2b7b709845ba7c947c5ec1664f56263bd089eff194d59f48e5aa8
R
1,861
48
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'md_DKI' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(m...
7bbe111c67e9e100ecf1879d363450a2d6d2dc1bcb9039fa9ff39738a6eb2a86
R
1,862
48
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'log_fc' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(m...
d5d16322101c3e5629c03cc0be9e00c28ecd60728c4276105a330292d6213027
R
1,863
48
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'kfa_DKI' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(...
cf5c745ebd664c993f7c799743a046a9480c8fde861318f0ca6532e17865eacb
R
1,865
49
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'OD_NODDI' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c...
6053151ad2f3439698bff7f14f3270a7a82845fb2d334d309ad7662d8a56afe1
R
1,869
48
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'ICVF_NODDI' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric =...
c3b48dcc88814afaa78ec52243736e367efebfd048f028fb93589434f2d75c72
R
1,896
49
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'fd' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(metri...
8748e6b471ef9329dc0d1245131c98ab99e7a28a32b8d17fe340142f2f98692a
R
1,910
49
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'log_fc' # metric to analyze (log_fc, fd, or fdc) # Define analysis and file paths metric = c(metric)...
c4fee9ca32b7faf532100c0c01cdf260631dd5cd9f2c7aad37152efca2eba4d2
R
1,926
74
--- title: "Fast Differential Expression with Presto" date: 'Compiled: `r format(Sys.Date(), "%B %d, %Y")`' output: github_document: html_preview: true toc: true toc_depth: 3 fig_width: 16 html_document: df_print: kable theme: united fig_height: 5 fig_width: 16 out_height: 4 -...
94fc6afbf1de6ecf9a481a06f491b0f4f3084149772ae006520a5e2a9bc8210f
R
1,931
48
# Load libraries library(ModelArray) library(testthat) knitr::opts_chunk$set( collapse = TRUE, comment = "#>" ) args = commandArgs(trailingOnly=TRUE) fba_dir = args[1] # path to FBA derivatives directory metric = 'fdc' # metric to analyze (e.g., log_fc, fd, or fdc) # Define analysis and file paths metric = c(metr...
043884503c6d1d1a6348c32d45f89394cced39711eb304c420efb7848b9a7f0f
R
1,935
59
library(glmnet) #mouse model tested w/ human data load("mouse/Robj/BC3MSD_CV-Lasso.Robj") #half lives, kmer kreqs, & codon freqs features a=readme("seqFeatWithKmerFreqs.txt.gz",gzip=T) a=a[,c(1:10,grep("Codon",colnames(a)),grep("3UTR",colnames(a)))] a$Codon.TAA=0 a$Codon.TAG=0 #augment matrix w/ mouse miRs -- set to...
a6d2296255d01db985ea57ded9874d777e80ccb4fcec9443d278928bd3e7135c
R
1,935
61
#Code to generate Video3 of the desmosomal connectome paper Jasek et al #Gaspar Jekely source("code/Packages_and_Connection.R") #read the saved visNetwork file from supplements/ conn_graph.visn <- readRDS("source_data/Figure3_source_data2.rds") # plot neurons by colours matching network pic -----------------------...
15d06ae0e7309ff1cafb743d9897b41c560dce5d024bd4ce80a596be7bc5cb7d
R
1,937
44
#!/usr/bin/env Rscript ################################################ ################################################ ## REQUIREMENTS ## ################################################ ################################################ ## TRANSCRIPT ISOFORM DISCOVERY AND QUANTIFICATION...
a15a4ae025c29ce617e67f654438282e14579dffeca5f6f5e0c9790ceb0dd277
R
1,949
63
#' Prepare Training and Test Dataset #' #' @param data A `data.frame`. #' @param col_to_vars A character vector specifying the predictive columns. #' @param col_to_label A column indicating the labels/classes. #' @param label_names Label/class names. The order is important. For example, #' "a", "b", "c" will be transfo...
fc6a394d9dc46a46c64ddf4949e98dfc1ffbd8fa3c79158fb339bdd744683adf
R
1,953
58
### Read-in MaAsLin2 output df.mas <- read_tsv( paste0( "data/MaAsLin2_Analysis/Species_genotype_diet_maaslin2_output/all_results.tsv"), col_names = T ) df.mas.sig <- df.mas %>% filter(qval < 0.25) df.plot.nonsig <- df.mas %>% filter(qval > 0.25) %>% pivot_wider( !value, values_fro...
612c7dae27782ec720163fe4ad7f2d348fdb433c3a0ebe23d977908621a74b8c
R
1,960
45
# Create flowchart flowchart <- grViz("digraph flowchart { node [fontname = Calibri, shape = rectangle, fontsize = 16] tab1 [label = '@@1'] tab2 [label = '@@2'] tab3 [label = '@@3'] tab4 [label = '@@4'] tab5 [label = '@@5'] tab6 [label = '@@6'] tab7 [label = '@@...
3216bfe4d50aabde9b4fcf2f85e7b8f12c6e5194d8f853956f8e6296721f8b49
R
1,963
51
# GSEA plot display labels with short = TRUE (SPEC-RICHR-003 REQ-011). Fork-only: # relies on the GSEA result layout of SPEC-RICHR-002 (pathway = identifier, # Term = label). Two pathways whose labels differ only in a whitespace run must # stay two categories after shortening. gsea_ws_result <- function() { genes <-...
75185e06939f582fcff40a366630e7973d18a660ace9bb46b63e6ef8b2fe4500
R
1,968
63
# Contains functions responsible for separate plot functionalities via flow = FALSE. # # Contains `separate_idx`, `remove_last_ele_from_nested_list`, `create_xlabs_for_sankey` functions. # Separate idx function # TODO Add documentation with the roxygen format separate_idx <- function(idx, paired) { separated_idx <- ...
a318427c09030b387062640d96e21d7ac9664a1dead70b059306f539e7829ac6
R
1,973
68
#all kinship functions should follow the template: #kinship_SOMETHING = function(SNP_matrix){...} #where "SOMETHING" is the name of the algorithm or some distinctive string #and SNP_matrix is SNP matrix, markers as rows, samples as columns, values in 0/1/2 #(or more) in case of polyploids library("sommer") library("ma...
d029f6b649e984742e0a132ea135b7cf21c4baa565205a92cc1710a9b26cbfbe
R
1,978
56
library(Seurat) library(dplyr) pbmc.data <- read.table('CASE.txt',sep='\t',check.name=F,row.names=1,header=T) pbmc <- CreateSeuratObject(raw.data = pbmc.data, min.cells = 3, min.genes = 200, project = "Natalie") #save(pbmc,file='CASE_raw.RObj') mito.genes <- grep(pattern = "^mt-", x = rownames(x = pbmc@data), value ...
31dadc70b1ea7ae1c06170bc55c24e501c9ddb17f7f6c1c3f816f5748857bddc
R
1,982
74
--- title: "Zero-preserving imputation with ALRA" date: 'Compiled: `r format(Sys.Date(), "%B %d, %Y")`' output: github_document: html_preview: false toc: false html_document: df_print: kable theme: united --- This vigettte demonstrates how to run ALRA on Seurat objects, which aims to recover mis...
f21ee2cdd5db78f0c6f71cb8844687d1ab020c3c7d59a90f6741865de39248a4
R
1,992
72
#! /usr/bin/Rscript ########## Hierarchical clustering ########## #' Generate vectors containing needed variables #' #' norm_val: contains normalized values (column 9 or other depending on the normalization step) #' geneID: contains gene names (unique occurences) #' samples: contains sample names (unique occurences...
b25a793d3717b20d2a9e4547f13a781bba5b9fd612fd1453f710eca680c40e4e
R
1,996
69
# alignReplicates() - model parsing ---------------------------------------------- test_that("alignReplicates() - model parsing", { simDataWideFile <- system.file( "extdata", "simDataWide.csv", package = "blotIt" ) input_data <- readWide(simDataWideFile, description = seq_len(3)) expe...
94e0e2ccf69a83efed5c8399b2a616b0fdf297888aa45418660c9aa383539a0a
R
2,011
66
install_ez_packages <- function(answer = T) { if (answer == T) { if (!requireNamespace("BiocManager", quietly = TRUE)) install.packages("BiocManager") BiocManager::install(pkgs = c("tidyverse", "R.matlab", "tidyr", "rlang", "flowCore", "ks", "flowVS", "flowViz", "RColorBrewer", "gtools", "gplots","ggpub...
84c25e8cd218a7f2a663b6ad938fc8d1ac2e37a501bc92203f456946793ad169
R
2,023
69
library(tidyverse) setwd(dirname(rstudioapi::getActiveDocumentContext()$path)) d = read_csv(paste0(rstudioapi::getActiveDocumentContext(), "/data/CCLE_expression_full.csv")) dim(d)#1377 52055 #transpose ds = as_tibble(cbind(gene = names(d)[-1], t(as.matrix(d[,-1])))) colnames(ds)[-1] = d[[1]] #make sure the columns...