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The Fun Gambling Blog
Casino & Betting Insights Galore!
AusVegas Real Money Casino
Enjoying Rugby Betting Action Online
Rugby is a popular ball sport in the UK, and it also has a dedicated following as far afield as Japan and Argentina, along with many other nations that were once ruled by the British Empire. Related to both American football and Gaelic football, Rugby also comes in three major forms: Rugby Union, Rugby League and Aussie Rules Rugby.
Sports fans are often keen punters as well, and Rugby fans are no exception. Bets on matches have been commonplace since the sport’s inception, and land-based betting operations have offered a range of bets on Rugby matches for ages. The growth of online and mobile betting has expanded the sport’s reach even more, and punters can now place a wide variety of bets on different facets of the game anytime they feel the urge, simply by logging on to a sports betting site that offers Rugby.
Sports Betting Requires Basic Precautions
All of the same rules that apply to sports betting at land-based operations also apply to online and mobile betting sites: only use the most reputable ones, only bet money you can afford to lose, and remember that long odds are long for a reason. But there are one or two other checks punters should complete before they wager on Rugby via the Internet.
Secure encryption is obviously the most important: reputable online Australian betting sites will show proof on their home page that their encryption software is up to date, so punters know their accounts will not be hacked. If a site doesn’t display proof of proper security, it isn’t reputable. A solid privacy policy is also important. Shady sites may sell on personal details to third parties, leaving punters vulnerable to irritating spam or worse, so privacy policies should be closely investigated too.
Options Appear to be Unlimited
The story of William Webb Ellis picking up a soccer ball and inventing a new sport at Rugby School is probably apocryphal, but new variations do seem to be a thread running through Rugby history. This is attested to by the number of different versions of the game, which these days include Sevens Rugby and more.
Similarly, online betting sites are centres of new innovations constantly. If a punter chooses, they can bet simply on which side will win a Rugby match. But throw in a points spread, bets on specific scores, bets on the total points scored by individual players, and lots of other variations, and the Rugby punter has a bewildering variety of bets to choose from. These options expand constantly, so online betting on Rugby is likely to remain popular for many years.
Watch and Bet on Big Tournaments Live
Live streaming is another feature attracting more and more punters to both online Rugby betting and cricket betting. On the same page where they place their bets, punters can watch the match they are betting on in real time. This helps to make the online betting experience similar to really being at the game.
Live streaming also allows the player to weigh up how the game is going, and place extra bets during the game on specific outcomes, where this is appropriate and permitted. All in all, online betting allows punters to enjoy interactive Rugby from wherever they happen to be.
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Rio is broke - just in time for the Olympics
MarkV
The governor of the state of Rio de Janeiro has announced that there is no money left for public services and declared an emergency. A fizzing grenade tossed in the lap of the new and possibly very interim president of Brazil.
Human history becomes more and more a race between education and catastrophe (H G Wells)
Mit der Dummheit kaempfen Goetter selbst vergebens (Friedrich von Schiller)
It's going to be an interesting Olympics this time around. We can hope that the corrupt IOC learns something from this mess and awards the games only to those country's that can afford them.
The IOC was corrupt - no argument - but partly as a result of the Salt Lake City scandal it had a complete clean out and restructure before the London games and is generally considered no longer corrupt (unlike FIFA). Doesn't mean that they can't be incompetent though. Don't forget however that when the games were awarded to Rio (the games are awarded to a city not a country) Brazil was regarded by most economists as being one of the new giants of growth alongside China, India and Russia, since then its economy has been mismanaged by a government both incompetent and corrupt and the oil price has also fallen through the floor. Don't think the IOC can be blamed for not predicting that.
Last edited by MarkV; 18 Jun 16, 09:21.
III Corps
...It's going to be an interesting Olympics this time around...
Zika.
Arnold J Rimmer
Man, they can't give the Winter games away, and now the summer games are in trouble.
Any man can hold his place when the bands play and women throw flowers; it is when the enemy presses close and metal shears through the ranks that one can acertain which are soldiers, and which are not.
Seems to me holding the Olympic Games in a plague area is the height of foolishness. I suppose old people will show up but I wouldn't go even if I was guaranteed a gold medal...
Brazil has many problems but the plague is not one of them. Disease carrying mosquitoes are what I think you mean. The hope is that it being winter in Rio they will not be very active but it is still a risk.
They're holding the Olympics in a Socialist heavy, crime ridden, South American nation with a corrupt government (as if that needed mentioning...) and they're surprised that the arrangements are screwed beyond recognition and the nation is broke?
ob·liv·i·ous.
[əˈblivēəs]
1.not aware of or not concerned about what is happening around one:
"she became absorbed, oblivious to the passage of time" ·
synonyms: unaware of · unconscious of · heedless of · unmindful of ·
© Oxford University Press
Originally posted by MarkV View Post
There's the sewage problem.....
http://www.businessinsider.com/rios-filth-is-already-spoiling-the-2016-summer-olympics-2015-7
As I said - many problems but can probably be summed up as Crap, Crime, Contamination and Corruption but I always found the Brazilians easier to deal with than the Portugese
nikolas93TS
ACG Forums - General Staff
São Paulo and Rio de Janeiro already total for annual transit of over 30 milion tourists, so I guess they know how to handle foreigners well.
Soccer World Cup in South Africa was better as location, as far as criminality and social issues are concerned? Yet nothing tragic occurred...except vuvuzelas, of course.
Naturally, additional health precautionary measures are necessary.
It is always more difficult to fight against faith than against knowledge.
Косово је Србија!
Never go to war with a country whose national holiday celebrates a defeat in 1389.
Armored Brigade
Armored Brigade Facebook page
Originally posted by nikolas93TS View Post
And as I can testify are pretty empty during the winter months (which is when the games are on) so all those hotels, bars, restaurants etc will be gagging for customers.
Mind you the pickpockets will be glad to see them too.
slick_miester
You can say that again. Dealing with Pork Chops is like bashing your head against a rock -- repeatedly.
I was married for two ******* years! Hell would be like Club Med! - Sam Kinison
One somewhat worrying effect of running out of money
http://www.bbc.co.uk/news/blogs-trending-36653007
Wooden Wonder
MarkV - All in all, I think I will give the Olympics a miss this year. I do hope those who brave out all the issues have a good experience, though.
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Impact ~ NEO; Near Earth Objects
Previous 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 template Next
Since underground nuclear explosions are conducted in specially constructed deep chambers, and thus representing the collapse of not only the chamber itself but the strata surrounding the chamber, can they be validly compared to craters created by surface impacts of non-explosive solid objects?
Judging by the total lack of any response, apparently they cannot be validly compared.
Speaking for myself, rather busy of late and limited time for all the threads, I remember seeing this and intending to respond.
For the most part, impacts of solid objects usually tend to throw out material, ejecta, and/or produce raised rims. There's also materials at or just below the surface reflecting alteration from the heat of impact, something that seldom transfers up from underground nuke detonation. Also could be fracturing and shattering of strata layers evidence force and heat from above rather than below.
But I'm not a geologists, so perhaps The Doctor would be better at chiming in.
Comet ISON shaping up to be a spectacular display
http://phys.org/news/2013-01-comet-i...ectacular.html
Comet ISON is expected to be at its brightest in late November of this year, leading some to link it with the Star of Bethlehem which the Bible says led the three wise men to the newborn baby Jesus. Its perihelion – closest approach to the sun – is expected to occur on November 28 and the comet will likely be best viewed in the northern hemisphere.
Read more at: http://phys.org/news/2013-01-comet-i...cular.html#jCp
Excitement is mounting for astronomers and star gazers the world over as word spreads that Comet ISON may go down in the history books as one of the flashiest ever. First discovered in September of last year by Russian astronomers, Vitali Nevski and Artyom Novichonok, Comet ISON (C/2012 S1) has been drawing attention ever since.
Talk about close! Asteroid to give Earth record-setting shave
Close flyby comes on Feb. 15 — but NASA says it won't smash into our planet
"" An asteroid half the size of a football field will give Earth the ultimate close shave this month, passing closer than many satellites when it whizzes by. But it won't hit the planet, NASA scientists say.
The asteroid 2012 DA14 will fly by Earth on Feb. 15 and zip within 17,200 miles (27, 680 kilometers) of the planet during the cosmic close encounter. The asteroid will approach much closer to Earth than the moon, and well inside the paths of navigation and communications satellites.
"This is a record-setting close approach," Don Yeomans, the head of NASA's asteroid-tracking program, said in a statement.
... ""
http://www.nbcnews.com/id/50672151/n.../#.UQ6swfLheKw
If it does hit, would be about like the Tunguska Blast of 1905.
Pirate-Drakk
Of course you can. A crater is a crater no matter how it is formed.
Another interesting thing about the Barringer crater is the lack of debris field or "splotch" of ejecta around it. In the desert there is no vegetation to and little water to obscure such marks and this is a young impact.
3619478521_8c8159f573_z.jpg (170.5 KB, 48 views)
Battles are dangerous affairs... Wang Hsi
Hida Akechi
I've been there. It's amazingly flat surrounding that crater. A stark reminder of just what can happen to our planet.
The First Amendment applies to SMS, Emails, Blogs, online news, the Fourth applies to your cell phone, computer, and your car, but the Second only applies to muskets?
Originally posted by Pirate-Drakk View Post
... Another interesting thing about the Barringer crater is the lack of debris field or "splotch" of ejecta around it. In the desert there is no vegetation to and little water to obscure such marks and this is a young impact.
That is interesting. Any theories you like as to why that is?
Actually, at least in this article, there is a debris field:
"Limestone blocks as massive as thirty tons were tossed outside the crater’s rim, and debris from the impact has been found over an area of 100 square miles."
"Relatively large chunks of nickel-iron fragments, ranging from gravel size to blocks weighing up to 640 kilograms have been recovered from the debris field surrounding the crater."
http://www.philipcoppens.com/meteorcrater.html
It does look like there is no debris field, especially from simply looking at the pictures. I have never heard before that the area lacked a debris field.
Originally posted by Hida Akechi View Post
100 square miles sounds like a lot but when you do the math, the furthest debris is only 5 miles from the crater and amounts to a few pebbles.
When I think debris fields, they look like the fresh craters in the pics below. The first two are from Luna, the other two are from Mercury.
hrp111.jpg (198.0 KB, 1 view)
04_07.jpg (377.2 KB, 1 view)
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Ok, I understand then. But those are on worlds that don't have erosion or new soil laid down. Granted Meteor Crater is in the middle of a desolate nowhere, but those processes do happen in that area anyway.
The article did mention much larger boulders thrown up from the impact. So it's more than just a few pebbles.
But I'm not quibbling, I understand by what you mean now when you say "debris field". Utter ejection devastation. Like I said, I have been to the crater, I have seen ejecta laying about, but not on the scale of the pictures you present.
And if it is an actual mystery as to why there isn't, at least, more debris, then I'm inclined to wonder why as well.
Thanks for the brain-excercise!
Your welcome, I also enjoy oddities I can't explain. Recall from this thread of mine:
http://www.armchairgeneral.com/forum...d.php?t=131466
"Simple craters generally have depth / diameter ratios of between 1/5 (0.2) and 1/3 (0.33) (Melosh, 1989)."
http://www.geologyrocks.co.uk/tutorials/meteor_craters
If we take the numbers from the wiki:
http://en.wikipedia.org/wiki/Meteor_Crater
We get: 170m/1186m = 0.143
This does not fall into the range of a "normal" simple crater which this appears to be.
So, we have a "crater" that does not fit the depth to diameter ratio, it lacks a significant debris field, and it is square instead of round.
I would say this is not much of an impact crater based on the actual evidence and science behind cratering. However, it is indeed a crater.
Here's a way to make craters of various types.
From page 234 of this interesting document:
http://www.osti.gov/bridge/servlets/...852629-81nrD8/
As you can see, all manner of ratios of diameter to depth ratios can be generated depending on the specifics of the blast parameters.
The explosions don't require nukes. You will get the same result for the same amount of bang out of any explosive.
All of the "mysteries" of the Barringer crater can be explained by an underground blast. The lack of radioactive debris in the area indicates it was not a nuclear explosion.
This underground blast theory can explain the crater, but not the "who", "when", and "why" questions that would be related if it were true...
800px-Nuclear_explosion_craters_schema_1.png (56.8 KB, 47 views)
New proof that asteroid impact dealt the dinosaurs a quick death blow
Timing of an impact
New findings using high-precision radiometric dating analysis of debris kicked up by the impact now suggest the K-T event and the Chicxulub collision happened no more than 33,000 years apart. In radiometric dating, scientists estimate the ages of samples based on the relative proportions of specific radioactive materials within them. [Wipe Out: History's Most Mysterious Mass Extinctions]
"We've shown the impact and the mass extinction coincided as much as one can possibly demonstrate with existing dating techniques," researcher Paul Renne, a geochronologist and director of the Berkeley Geochronology Center in California, told LiveScience.
http://science.nbcnews.com/_news/201...eath-blow?lite
Some more on 2012 DA14, this article was handy for the link it provided;
http://news.cnet.com/8301-11386_3-57...coming-friday/
which is this asteroid impact calculator;
http://www.purdue.edu/impactearth
And a more informative article (as to be expected) from space.com;
http://www.space.com/19759-asteroid-...ving-tips.html
Another addition:
Asteroid 2012 DA14: 5 Surprising Facts About Friday's Earth Flyby
http://www.foxnews.com/science/2013/...intcmp=related
Last edited by G David Bock; 14 Feb 13, 21:05.
PhilipLaos
Lord Of The English Manor
Maybe that large asteroid is bringing along some baby companions.
From: http://www.reuters.com/article/2013/...91E05Z20130215
Reuters) - A powerful blast rocked the Russian region of the Urals early on Friday with bright objects, identified as possible meteorites, falling from the sky, emergency officials said.
"It was definitely not a plane," an emergency official told Reuters, without elaborating. "We are gathering the bits of information and have no data on the casualties so far."
No one was hurt in a meteor shower, an emergency official told RIA-Novosti. Local residents said they witnessed burning objects in the sky of the Chelyabinsk and Sverdlovsk regions.
A Reuters witness in Chelyabinsk reported hearing a huge blast early in the morning and feeling a shockwave in a 19-storey building in the town center.
The sounds of car alarms and breaking windows could be heard in the area, the witness said, and mobile phones were working intermittently.
"Preliminary indications are that it was a meteorite rain," an emergency official told RIA-Novosti. "We have information about a blast at 10,000-meter (32,800-foot) altitude. It is being verified."
The trace from a falling object could be seen in Yekaterinburg, some 200 kilometers (125 miles) southeast of Chelyabinsk, another Reuters witness said.
"The whole problem with the world is that fools and fanatics are always so certain of themselves, and wiser people so full of doubts."— Bertrand Russell
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[Sensor_Name: Short_Name='TEMPERATURE SENSORS']
LBA-ECO CD-04 CO2 and Heat Flux, km 83 Gap Tower Site, Tapajos National Forest
Entry ID: CD04_Tower_Flux_Gap_978_1
Abstract: This data set reports 30-minute values for above-canopy meteorology and fluxes of momentum, heat, and carbon dioxide, and within-canopy carbon dioxide and water vapor concentrations collected at 12 levels between 10 cm and 64 m at the tower located within a logging gap at km 83 Tower Site in the Tapajos National Forest, Para, Brazil. Data were collected over 1.5 years between June 3, 2002 and ... January 30, 2004. All of the data are contained in one comma separated file.Two towers are located at the km 83 site. The first tower was installed in an intact forest area at this site in June 2000 (the 'intact' tower). In September 2001, the area adjacent to the tower was selectively logged (Bruno et al., 2006). The second tower (the 'gap tower') was installed and operating in June 2002, 400 m east of the intact tower. The gap tower was installed in the middle of a 50 m x 50 m log landing.
Description: This link allows direct data access via Earthdata login
Description: ORNL DAAC Data Set Documentation
Description: Data set Landing Page DOI URL
Description: Data Set Documentation
Description: Browse Image
Other Citation Details: Miller, S.D., M.L. Goulden, and H.R. da Rocha. 2010. LBA-ECO CD-04 CO2 and Heat Flux, km 83 Gap Tower Site, Tapajos National Forest. ORNL DAAC, Oak Ridge, Tennessee, USA. http://dx.doi.org/10.3334/ORNLDAAC/978
Dataset DOI: 10.3334/ORNLDAAC/978
FIXED OBSERVATION STATIONS
SONIC ANEMOMETER
IRGA > Infrared Gas Analyzers
LBA-ECO > Large Scale Biosphere-Atmosphere Experiment - Ecology
THE OAK RIDGE NATIONAL LABORATORY (ORNL) DISTRIBUTED ACTIVE ARCHIVE CENTER (DAAC)
Data Center URL: https://daac.ornl.gov/
Name: NOT PROVIDED
rucontenttype: >GET RELATED VISUALIZATION>
ProcessingLevelDescription: Variables mapped on uniform space-time grid scales with completeness and consistency
UUID: 0e30d5c3-d445-42bb-94d3-4404f4ce1a36
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Home / Computers/technology / Mobile / Facebook Introduced A New Advertising Platform
FACEBOOK INTRODUCED A NEW ADVERTISING PLATFORM
The social media and tech giant, Facebook, has announced the arrival of several tools for businesses that will be introduced into the social platform and other media outlets as well as Instagram.
Augmented reality will now allow users and customers to try on products such as sunglasses through Facebook. Then, utilising the power of social media, the platform allows sharing what you look like to the community or straight to the store.
In the summer of 2016, the Pokémon GO game created a global firestorm obsession, which still continues, with augmented reality at its core that changed the direction of how application and games were developed. With the number of augmented reality users growing, in May 2018 Facebook announced the release of a new toolkit that would allow software developers to repurpose augmented reality to allow potential customers to connect with their brands and effectively experience their product before actually purchasing or downloading.
For example, Sephora, one of the first businesses that were given access to the feature, can use augmented reality to allow customers to 'try on their cosmetics'. First, on Facebook Messenger, augmented reality will now make its way to the news feed, with a number of businesses testing out the new advertising tool, such as Micheal Kors, who uses the tool in ads to allow people to try on a pair of sunglasses and then decide to purchase based on their experience.
Additionally, in an attempt to rival YouTube, Facebook also announced the release of a new video creation kit which will allow users to create mobile-friendly advertisements by using images and overlays while incorporating your business’ logos. Early access to this kit, claimed a "77% increase in performance compared to the original static assets that ran on Facebook."
After the release of Instagram's new IGTV extension, the social media outlet under the Facebook umbrella will start to expand its shopping department as well, with tags acting as links directing to products previously found in posts, now expanding to stories for select brands, and available to all businesses by the holiday season.
The campaign feature 'collection' that combines video, images and products in a catalogue-like format also available in the near future.
Article Tags: Instagram Facebook Augmented Reality AR IGTV Facebook advertising platform Social media giant
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John Cho Joins as a Series Regular of ‘The Exorcist’
by María Garduño
As reported by Entertainment Weekly, John Cho (Star Trek) has joined The Exorcist’s cast for the second season, which got a renewal back on May.
The Exorcist is a Fox drama, based on the novel The Exorcist, starring Alfonso Herrera (Sense8), Ben Daniels (House of Cards) and Geena Davis (Thelma & Louise). The series follows the story of two priests, Father Thomas and Marcus (Herrera and Daniels respectively), who must save a family terrorized by a dark presence in their home.
John Cho will join Herrera and Daniels as Andrew Kim, a former child psychologist who now runs a group home for at-risk foster children. His path will cross with Father Tomas and Marcus’ search for evil when one of the kids under his care becomes the target of a demon.
Jeremy Slater, creator of the show, told EW back when the series was renewed what we might expect from this next season.
“You’ll see a new possession case, a new family or individual who needs Marcus and Tomas’ help in season 2, and at the same time you’ll see our larger mythology. The world is starting to change around Marcus and Tomas and their enemies are getting more ambitious and are taking moves to consolidate power. So, trying to balance that political paranoia of never quite knowing who you can trust, with another strong emotional story about these two different men coming together to save a family in peril, that’s always going to be the basic DNA of The Exorcist.”
What do you think about this news? Are you excited for seeing John Cho? Have you seen The Exorcist? Let us know in the comments below!
The Exorcist will return on September 29.
Tagsfeatured • John Cho • The Exorcist
About María Garduño
Twitter: @mariegarduo
1 comment on “John Cho Joins as a Series Regular of ‘The Exorcist’”
Pingback: Tiffany Haddish Will Be Executive Producer Of ‘The Oath’ A Political Satirical Thriller, Which She Will Star With John Cho – WE ARE GEEKS OF COLOR
'Children of Blood and Bone' Fancast
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GemGenève - November 5 - 8, 2020
Ticketing soon
Ming Lampson is one of the new names in this year’s Designer Vivarium, presenting the work of individual, independent designer-jewellers from around the world. Based in London, Ming was born in Hong Kong – hence her name – and drawn to gemstones from an early age, as so many of the designers were, she went on to study gemmology and learn about stones in Jaipur. She set up her own business, in 1998, as a bespoke jeweller, only working on commission, but in the last few years she has created two collections, both inspired by the East, by Asia and her roots.
The first collection, Oriental Garden, was conjured from Ming’s personal fantasy of an Asian garden, stylized, manicured, filled with fragrant, exotic plants and alive with winged creatures. The designs, as always with Ming’s work were highly stylized, abstracted, evoking emotions rather than depicting realistic images, a pool of lapis in which floats a single green tourmaline, representing a lotus leaf, a caterpillar translated into a ripple of emeralds encased in rose gold, an opal dragonfly ring with openwork wings wrapping the finger. Her second collection, Reverence for Nature, revolves around the Japanese preoccupation with the seasons. Ming explains, “I wanted to capture something fleeting in materials that last forever”. Again the designs are stylized, and gemstones are the focal point of each jewel; blossoms, for spring, a rendition of the traditional ‘Mons’ style flowers, in lace-like diamonds on ring; wintry aquamarine ice flowers, cold, sleek and sharp shards of ice; ripe, succulent berries for autumn, vibrant turquoise flowers for summer. She says she has explored the stones, their colours and associations, and pushed herself to technical challenges, in the construction of the jewels, bringing fluidity, and a strong sculptural quality, particularly for her earrings in which she experiments with line and form, “dressing the ear”, blending the classicism of the subject with a very modern edge. Each jewel is one of a kind, and all are hand-made in Ming’s atelier in London.
GemGenève
Palexpo | Geneva | Switzerland
Copyright Gemexpo SA - Data protection
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Penn State University (logo)
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← Plax axed and Pace’s place
FR: Free agency (tri)weekly review pt. 4 →
Draft OP: Is Aaron Curry worth the top pick?
Let the bias begin…
As a Wake Forest grad, I watch a lot of Demon Deacon football. That’s especially true over the last three years because we (I paid that school enough dough to use that pronoun) have actually been good. It’s been a little surreal to see Wake go to three straight bowl games, given that during my college career the football team won six games. (Yes, that’s a total.)
Now, the Deacons have produced one of the best players available in this year’s NFL draft — LB Aaron Curry. Some have called Curry the most complete prospect in this year’s draft. For example, Curry was at the top of Mel Kiper’s March 26 Big Board. Such ratings have put Curry in the discussion for the No. 1 overall pick. But is Curry worth that lofty investment? Time for another outlandish prediction…
Curry is a three-year starter and four-year contributor who was a playmaker at OLB for the Demon Deacons. He won the Butkus Award in ’08 as the country’s best linebacker after recording 105 tackles, 16 tackles for loss, 2.5 sacks, and an interception. That followed an ’07 season in which he had 99 tackles, 13.5 tackles for loss, and 4 picks, three of which he returned for touchdowns. He had 83 tackles as a sophomore starter, including 8.5 tackles for loss. So he’s been productive throughout his career, and he’s gotten better and made more plays as he goes along. He’s a thick, solidly built guy (6-2, 250) who has good speed and instincts. He can play middle linebacker, strong-side backer in the 4-3, and could even play outside ‘backer in the 3-4. He’d be more of a Lamarr Woodley than a DeMarcus Ware in that scenario, but that could still work.
So Curry is versatile enough to play just about anywhere at linebacker, and he’s unlikely to bust out and become dominant at any of those spots. But is that worth the top overall pick? Linebackers who aren’t pure pass rushers usually aren’t worth top 8 draft positions. Keith Rivers (9th) and Jerod Mayo (10th) were the highest such picks last year; Patrick Willis (11th) was the highest in ’07; A.J. Hawk (5th) and Ernie Sims (9th) were the highest in ’06. All of those players have played well, and Willis and Mayo were defensive rookies of the year. Hawk isn’t measurably better than Mayo or Willis, even though he was picked five spots higher. Most players of this ilk seem to fit as great values in the draft starting with the ninth pick or so.
Still, pure linebackers who make their way into the 9 through 12 stratusphere typically pan out. (Remember, we’re omitting pass-rush OLBs like Vernon Gholston or DeMarcus Ware from this discussion.) Curry is a safe pick, and he would be great value on that tier. But those linebackers typically aren’t eye-popping impact players either. They’re more like clean-up guys who make the tackles they should and occasionally make a big play.
And that’s why, to me, Curry isn’t worth the No. 1 overall pick. He’ll be a good player, but he won’t be the kind of impact player that you’re looking for from the top overall pick. He’d be a lot like Russell Maryland, a DT who Jimmy Johnson made the No. 1 overall pick in 1991. Maryland was never a star, but he was a solid player who contributed to Dallas’ standout defenses in their three Super Bowls in that era. Maryland made just one Pro Bowl and never was a top-3 player at his position.
That, to me, will be Curry’s fate as well. He’ll be a very good player in the NFL, but not a great one. And in a year where quarterbacks and left tackles are available at No. 1 overall, that upside simply doesn’t justify the No. 1 overall pick. The Lions need to take either Matthew Stafford, Jason Smith, or Eugene Monroe, and the Rams should take one player out of that group as well. Curry doesn’t make much sense until Kansas City goes on the clock at No. 3. For the Chiefs at 3, the Seahawks at 4, or the Browns at 5, Curry would be a solid if unspectacular pick. He’ll be a good player wherever he goes. He just won’t be quite good enough to make a team forget that it passed on a burgeoning superstar with a top draft pick.
Filed under NFL draft, outlandish prediction
Tagged as a.j. hawk, aaron curry, ernie sims, jerod mayo, keith rivers, NFL draft, outlandish prediction, patrick willis
7 responses to “Draft OP: Is Aaron Curry worth the top pick?”
Don’t forget economics though, especially this year. You can’t really think that Stafford is a franchise QB. So if you’re the Lions, why get stuck paying him Alex Smith money. I understand that one of the OL may be what the Lions need (and ultimately, I think they go that route), but OL aren’t cheap either.
Consider the possibility that AC gives the Lions a pre-draft discount and signs early. Then, you’ve got a very solid LB core and a little bit of money to do other things.
I agree that the Chiefs at 3 make the most sense, especially when you consider the Patriots’ experience with Jerrod Mayo. But if the Lions pick him at 1, it’ll be over a slew of other guys who would be unspectacular themselves.
One last thing: consider that it’s the performance of guys like Mayo and Willis that have made teams consider using a higher pick on Curry. Certainly if those guys were being drafted this year, and we already knew they’d play like they have demonstrated they can in the NFL, those guys would be talked about at 1 and certainly 3.
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Watch the research project on hits and misses in the draft by position next week. The section on linebackers only highlights my position on Curry. I’d just feel much more comfortable picking him in the second five than the first five, just because you’d be missing out on a potential premium prospect (most of all Jason Smith, who I’d put No. 1 overall).
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Thunderhorns
As a Seattle fan, I’m happy we picked Curry. High character guy with alot of potential to be great.
I’m still not getting the idea that he can’t be a standout player in the NFL. He seems to have alot of upside and untapped potential, especially as a pass rusher. A guy like Belichek, Lebeau, or Johnson would love to have a guy like Curry and would find plenty of uses for him.
Not sure our coaches can do as well as those coaches, but I’m hoping Bradley will use Curry in a variety of ways that make opposing offenses have to look out for him. That’s the type of player I hope he’ll turn into. And the more guys you have like that on your defense, the harder it is for offenses to make plays against you. We already have one LB in Lofa Tatupu that teams take into account when they run plays, to have another would is going to be awsome.
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Posts tagged “telekinesis”
Friday The 13th, Part VII: The New Blood (1988)
Now that the Tommy Jarvis storyline had concluded, it left the door wide open for anything to be attempted in Friday The 13th, Part VII. Paramount had a great decision by hiring the awesome make-up effects master John Carl Buechler to direct the film, and then, there was the debut performance of Kane Hodder as Jason. There were workable elements in this film to make it great, but whenever I watch it, I just feel this doesn’t hit the mark. I don’t even think it’s a fault of MPAA censorship on the gore, of which there was an excessive amount. It just sort of feels like a poorly executed concept with not enough talent behind the script or in front of the camera to make it what it could’ve been.
Tina Shepard (Lar Park-Lincoln) has the ability of telekinesis, but this ability has haunted her for years now as it caused the death of her father on the docks of Crystal Lake when she was a little girl. As a young woman, she has returned to the lake with her caring mother Amanda (Susan Blu) and the deceitful and manipulative Dr. Crews (Terry Kiser), who wants to exploit Tina’s powers for his own fame. However, the teenage residents of Crystal Lake have something more to fear than Tina’s emotionally charged powers as she accidentally frees Jason Voorhees from his watery grave. He begins yet another killing spree, but is not prepared for the challenge Tina’s powers pose for the undead killer of Camp Blood.
I believe what I don’t like about this movie is the lack of worthwhile characters and fun. There was always a sense of levity in these movies from even a few light hearted characters. People that were just fun to spend some time with before the slaughter began. The only characters in this film making any jokes are the insensitive jerks that are not worth spending time with. Our female lead of Tina is far too troubled of a character to gain any levity or much relatability from. There’s really nothing accessible about the character in how she’s presented. I really don’t think Lar Park-Lincoln was a good casting choice in this instance. She really does nothing interesting with the character, and spends most of the time with very dour or pouty expressions on her face. The film starts out when Tina’s ten years old, but her behavior never matures beyond that of a child when we flash-forward. While she is an active part of the story, it still falls back into that trap with Tommy Jarvis from A New Beginning in trying to make a hero out of a depressed, introverted character. The potential of what this character could’ve been really required an actress of more textured emotional ability. I don’t have an issue with the telekinesis idea as it’s something that really could’ve worked very well, but I don’t think it was well realized here. It feels like a concept that was nothing more than something on the page. It wasn’t developed with a sense of depth in concept or with the actress. Like so much in this film, it’s flat and hollow. The various effects are good for it, but it just needed a stronger character and performance behind it to really sell that this is someone worthy of combating the powerful undead Jason.
The rest of the cast is rather forgettable due to the uninspired writing. These characters are once again shallow stereotypes played up for one note gags or bland character conflicts. Not much effort is put into writing them. I’ll grant that they are better realized stereotypes than most, maybe due to the decent acting talents here, but that doesn’t make them good. I’ll certainly take this cast and its characters over the boring, disjointed group from Friday The 13th, Part 3, but I’d still rather spend my time with a more entertaining array of people. On a side note, it’s an interesting retroactive quirk that Terry Kiser happens to be in this movie, and does get killed since he’s partly best known for playing a corpse in the two Weekend at Bernie’s movies. Kiser is a solid actor with a fine range, but the role of Dr. Crews is such a badly written, one note, obvious bad guy that there was nothing substantive here for him to work with.
The music of the film is terribly uneven. It features Manfredini cues recorded for Jason Lives and original pieces of score from composer Fred Mollin, and they don’t mesh at all. They have very different tones and approaches. Clearly, the Jason Lives music is a little lighter and more fun than the usual Friday The 13th scores mostly utilizing horns, and Mollin’s stuff is very heavy, dark, and menacing primarily using percussion and strings. It suits the more grim, merciless, and dark edge of the film’s tone. I have no idea why this mish mash of different scores were used, let alone why they used recycled recordings from the previous film. This would be fine if they were comparable, but they clearly are not. It would’ve been better to solely use Fred Mollin’s music throughout as I love everything he did in this film and in Jason Takes Manhattan. Mollin also did some fine work as the composer on the unrelated television show Friday The 13th: The Series. I think he took this film and the next into a far more dynamic and foreboding musical realm than Manfredini ever demonstrated.
The climax of this film, how Jason is defeated, is just a horrible idea that is terribly executed. There’s just so much possibility that could have been taken advantage of with the film’s premise, but what the filmmakers do is just plainly bad. I mean, you’re telling me that no one ever fished the body of Tina’s dad out of that lake to have a proper funeral? They just left him to decay at the bottom of the lake forever, and he just happens to come back to life without a bit of decay on him? In theory, it’s a nice reversal of the dream sequence ending from the first film, but I can’t buy Jason getting taken down in this ridiculous, piss poor manner. The build up to this moment is excellent. Great action beats with high production values really ramp up the danger and menace of Jason. So much is thrown at him, and he just keeps coming back, more pissed off than before. Kane Hodder even does a full body burn in a rather long take (slow motion or no). Buechler really makes the whole third act impactful and visually impressive, but to have it end the way it does just feels like someone’s slap dash idea who got too tired to write a proper ending to the film. It’s just a bad idea, through and through, which makes me want to forget I ever saw it.
I will credit the film for having a distinctly darker tone than the rest of the series. Visually, it’s very dark and imposing. It surrounds Jason in far more presence and aura than ever before. This is also a credit to Hodder’s performance. He created a very thorough body language and mentality for Jason, and it truly penetrated through the screen. It truly made Jason frightening again, even if the film itself lacked suspense, a decent plot, or good lead acting. I get that people are supposed to scream in horror movies, but Lar Park-Lincoln seems to inappropriately scream at the top of her lungs at almost everything in the third act. It’s like she’s not there inhabiting the scene as an actor enveloping herself in the mood, but just screaming as if that’s the only reaction people are supposed to have in a horror movie. There’s just no genuine fear or intensity in her performance, despite how purely menacing Kane Hodder is as Jason. I think his debut performance was absolutely his best. It’s just unfortunate that it wasn’t in a better movie.
Hodder is greatly aided by the stunning make-up design Buechler created for Jason Voorhees. Seeing the bones stick out from underneath the decayed flesh, and making use of the partially shattered mask to show just a glimpse of Jason’s zombified face are brilliant touches. This is a masterwork of special make-up effects artistry and craftsmanship, and is something that has not even been remotely challenged anywhere else in the franchise since. What gore we do get after the MPAA’s severe slashing of this film is exceptionally good, but even still, you hardly see any of it. This really was the most heavily edited down entry in the whole series of films, and I’m sure an uncut version would be filled with hardcore gore and graphic violence. That surely feeds into the overall darker, more aggressive tone of the movie. John Carl Buechler does give us a film that is nicely and consistently paced with a lot of creative kills that have become classics. However, it all does just feel like a blunt instrument due to a lack of real suspense. Anyone can show brutality and gore splattering across the camera lens. It takes a skilled filmmaker to tightly craft suspense, and Buechler hardly makes an attempt to deliver that integral part of good horror.
It’s been said that Paramount Pictures and New Line Cinema considered the crossover idea of Freddy vs. Jason at this time, but the two studios simply could not come to an agreement. Thus, what ideas Paramount had for the film were adapted for The New Blood – which is a horribly generic title for a slasher sequel. It’s hard to picture it aside from a protagonist with a supernatural ability, but I doubt they had anything more than a vague thought of a plot for a 1988 Freddy vs. Jason movie. Maybe just the thought of it got the screenwriters anxious to throw a more powerful adversary at Jason this time, and really push the supernatural angle further. Of course, I think the script could’ve used more work overall to develop its premise and characters beyond just base concepts.
The New Blood had some potential, and did deliver on inventive kills and a hard edged approach. It feels like a brutal horror movie, but without the graphic visuals to complement it, due to the MPAA required cuts. However, it really comes down to a weak script, and some uninspired casting choices that just make this an unimpressive sequel for me. This could’ve delivered it all, but ultimately, delivered very little of anything, in my view. There’s not much entertainment value that I take from this sequel as the characters are often yawn inducing with the lead of Tina Shepard being the biggest offender. Again, it is very difficult to give a damn about who lives or dies when the characters are badly written or poorly acted. I know this film has its big fans, but I just need more than edited down, suspense deprived brutality and Hodder’s great debut performance as Jason to win me over.
07.12.2012 | Categories: Friday The 13th, Horror Movies, Movie Reviews | Tags: abilities, crystal lake, film, franchise, fred mollin, friday the 13th, gore, harry manfredini, hockey mask, horror, jason voorhess, john carl buechler, kane hodder, killer, lar park-lincoln, movie, part 7, powers, psychic, review, sequel, series, slasher, sleeping bag kill, susan blu, telekinesis, terry kiser, the new blood, undead, violence | 1 Comment
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Expression of interests launched for new carrying-capacity studies for La Digue, Mahe and Praslin
The Seychelles Ministry for Tourism, Civil Aviation, Ports and Marine have recently launched 2 expression of interests for carrying capacity studies to be undertaken on La Digue as well as Mahe and Praslin. The aim of the studies is to determine the current status of the islands and the acceptable amount of tourism development that can occur while still remaining sustainable, and assist the government in taking informed decisions on all future tourism development projects.
The Carrying-Capacity Study for La Digue dates back to 2013 and the results have led to the policy directive of setting a moratorium on the development of tourism accommodation establishments to 5 rooms per developer. This moratorium is supposed to be valid for a period of five years and the time has come to commission a new Carrying-Capacity Study.
Moreover, in 2018 the President announced that La Digue would be a model of sustainability as part of the National Vision 2033. An eco-tourism strategy specific to the island for the next 15 years has been developed and the Carrying-Capacity Study on La Digue will aim to align with the established vision and provide recommendations to policy makers pertaining to future development on the island in view of assuring its sustainable development.
As for Mahe and Praslin, the Carrying-Capacity Study was commissioned in 2016 and set to be reviewed in 2020. The results of the Carrying-Capacity Study has led to a number of policy directives and a set moratorium on the number of rooms that can be developed per promoter which is 20 rooms for Northern Mahe and 24 rooms per promoter for the rest of Mahe and Praslin.
The carrying-capacity analysis will determine the ability of the ecosystem of La Digue, Mahe and Praslin and the various segments thereof to withstand all impacts of additional tourism development activities. The studies will apply the perspectives of Physical carrying capacity, Ecological carrying capacity, Social carrying capacity and Economic carrying capacity in order to develop a balanced overall assessment.
Consultants interested to undertake the study have to submit their expression of interest to the Department of Tourism by Friday, April 26, 2019 by 1500 hours. Results of the two carrying capacity studies will determine whether or not to maintain the moratorium currently in place on La Digue, Mahe and Praslin.
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eTN becomes a SUNx SDG 17 Partner calling for Climate Sanity in Tourism on Earth Day
In nature, nothing exists alone is the message for Earth Day 2019. Announcing the public launch of its “SDG17 Partners Program” on Earth Day 2019, Professor Geoffrey Lipman co-founder SUNx, calls and president of the International Coalition of Tourism Partners (ICTP) asks the Travel & Tourism sector to join its “Plan For Our Kids” and take the “Climate Sanity” Pledge.
Professor Lipman, former Executive Director at IATA, President of WTTC and Assistant Secretary-General UNWTO, said:
“I’m confident that Travel & Tourism will play a leadership role in the global shift to a New Climate Economy: we just need a pathway for change and that lies in our faith in the next generation”
SUNx a legacy for Planetary Champion Maurice Strong has created a “Plan For Our Kids”, aiming to recruit 100,000 STRONG Climate Champions to advance its vision of a no Carbon 2050 sector totally compliant with the evolving goals of the Paris Accords.
He added “During the past year we have seen a welcome intensification of the pressures for a new commitment to Climate Sanity, which stops discussing whether climate change is existential and just gets on with solutions. That’s the common message from Greta Thunberg’s Friday’s for Futures and AOC’s Green New Deal: it’s the message from Earth Scientists and Nobel Economists: it’s the plea from Sir David Attenborough.
”Lipman concluded “SDG 17 Partners will share our long-term vision on the fact that Climate Change is eXistential and that we have to act NOW, as if this Earth Day is the first day of the rest of our lives. We all have different starting positions, based on our separate realities: but we have a shared goal of meeting the Paris Agenda and together taking a “No Carbon 2050 moonshot”. We can deliver Climate Friendly Travel ~ measured plans: green growth: 2050 no carbon proof “
Juergen Steinmetz president of the eTN Corporation said “We are proud to become a SUNx SDG 17 Partner and provide preferential support for this great cause. As long as I have known Geoffrey Lipman, he has been drumming home the message that Climate Change is eXistential and that if we don’t fix it now, it will fix us. We are in, and will use all our links, like ICTP and the African Tourism Board to support Climate Friendly Travel. going forward”.
For more on SUNx and its SDG 17 Partnership Program please contact: go to www.thesunprogram.com
What is Earth Day?
The first Earth Day on April 22, 1970, activated 20 million Americans from all walks of life and is widely credited with launching the modern environmental movement. The passage of the landmark Clean Air Act, Clean Water Act, Endangered Species Act and many other groundbreaking environmental laws soon followed. Twenty years later, Earth Day went global, mobilizing 200 million people in more than 190 countries and lifting environmental issues onto the world stage.
On April 22, 1970, millions of people took to the streets to protest the negative impacts of 150 years of industrial development.
In the U.S. and around the world, smog was becoming deadly and evidence was growing that pollution led to developmental delays in children. Biodiversity was in decline as a result of the heavy use of pesticides and other pollutants.
The global ecological awareness was growing, and the US Congress and President Nixon responded quickly. In July of the same year, they created the Environmental Protection Agency, and robust environmental laws such as the Clean Water Act and the Endangered Species Act, among many.
One billion people
Earth Day is now a global event each year, and more than 1 billion people in 192 countries now take part in what is the largest civic-focused day of action in the world.
It is a day of political action and civic participation. People march, sign petitions, meet with their elected officials, plant trees, clean up their towns and roads. Corporations and governments use it to make pledges and announce sustainability measures. Faith leaders, including Pope Francis, connect Earth Day with protecting God’s greatest creations, humans, biodiversity and the planet that we all live on.
Earth Day Network, the organization that leads Earth Day worldwide, has chosen as the theme for 2018 to End Plastic Pollution, including creating support for a global effort to eliminate primarily single-use plastics along with global regulation for the disposal of plastics. EDN is educating millions of people about the health and other risks associated with the use and disposal of plastics, including pollution of our oceans, water, and wildlife, and about the growing body of evidence that plastic waste is creating serious global problems.
From poisoning and injuring marine life to the ubiquitous presence of plastics in our food to disrupting human hormones and causing major life-threatening diseases and early puberty, the exponential growth of plastics is threatening our planet’s survival.
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China announces Great Wall “emergency repair” over next 5 years
China’s government has formulated an emergency work plan to repair dilapidated sections of the Great Wall in the next five years, according to the municipal cultural heritage authorities.
The work plan has set 2,772 meters of the Great Wall and 17 towers as the priority for “emergency repair” over the next three years.
Beijing boasts a total length of 520.77 km of the Great Wall, which is more than 21,000 km long and traverses through 15 provinces and cities.
Since 2000, Beijing has earmarked 470 million yuan (70 million U.S. dollars) for the Great Wall protection fund.
In the next stage, the city has planned to comprehensively protect and develop the Great Wall Cultural Belt, with a total area of 4,929.29 square km, which includes both heritage protection and ecological conservation.
Shu Xiaofeng, director of the Beijing municipal administration of cultural heritage, said Beijing will make use of scientific and technological means, such as unmanned aerial vehicles and sensors, to protect and monitor the Great Wall, and carry out archaeological research.
He said the protection of the Great Wall is not only to protect the wall itself, but also to protect cultural relics along the cultural belt.
The Great Wall, a UNESCO World Heritage Site, consists of many interconnected walls, some dating back 2,000 years.
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How Emirates is supporting and preserving biodiversity
Taking its environmental responsibilities seriously and championing wildlife conservation across different corners of the planet, the Emirates Group is playing its part to support and preserve biodiversity.
The Dubai Desert Conservation Reserve and Emirates One&Only Wolgan Valley in Australia both illustrate the Group’s long-standing focus on protecting fragile ecosystems and support for sustainable tourism in very different parts of the world. Both conservation reserves protect valuable ecosystems and at the same time provide unique and sustainable experiences for visitors from around the world.
The Dubai Desert Conservation Reserve
The Emirates Group funds the operations of the 225 square kilometre Dubai Desert Conservation Reserve (DDCR), an inland desert habitat that has been protected by government mandate since 2003. This is the largest piece of land that Dubai has dedicated to a single project and aims to preserve Dubai’s unique desert environment for future generations. The DDCR plays an important role in ecological research, actively collaborating with both local and international universities. The findings and results of the research studies help to enhance knowledge of the desert ecosystem, gather scientific data around rare and endangered desert species, monitor its balance and preserve its natural environment.
The reserve is also a focal point for conservation programmes aimed at restoring populations of some of the UAE’s wildlife, such as the Arabian gazelle, sand gazelle and Arabian oryx. Since their reintroduction into the DDCR, the antelope species have thrived, and their populations have significantly increased, triggering the process of looking into relocating some oryx and gazelle species to other protected areas within the region. Over 250 endangered Macqueen’s bustard (houbara) were also released this year with 25 of them fitted with tracking devices to monitor their movement and breeding progress.
In 2018, the DDCR was visited by more than 285,000 tourists, through Arabian Adventures, various Emirates partner tour operators, and the Al Maha Desert Resort. The DDCR offers low-impact desert experiences in addition to desert clean-up activities in coordination with Arabian Adventures. During 2018 the DDCR was accepted as a candidate for the IUCN Green List for Protected and Conserved Areas, a global standard for the world’s most effectively managed Protected Areas.
Emirates One&Only Wolgan Valley
Emirates has been supporting the protection of Australia’s extraordinary wildlife and plant life for over 10 years, through the conservation-based Emirates One&Only Wolgan Valley in New South Wales. The property was the first luxury resort in the world to receive an internationally-recognised carbon neutral certification from New Zealand based CarboNZero, undergoing a comprehensive greenhouse gas emissions assessment. Emirates One&Only Wolgan Valley also conducts regular research to identify opportunities and challenges for endangered species conservation. Efforts have also been underway to help restore vital vegetation and tree planting activities, which have helped to re-establish habitats for vital bird populations, essential for their long term survival.
Emirates and Emirates One&Only Wolgan Valley jointly funded the development of the WomSAT app and website in collaboration the University of Western Sydney to help researchers identify opportunities for wombat conservation. Wombats are threatened by sarcoptic mange, an unpleasant and often fatal skin disease that afflicts Australia’s largest burrow builder. The tool is used to record wombat sightings and track population health to help treat wombats afflicted by sarcoptic mange. Emirates One&Only Wolgan Valley is also spearheading a number of other conservation projects, such as the Wolgan River Restoration Project, an ongoing weed management programme, and supporting research projects with Western Sydney University.
United for Wildlife and The Buenos Aires Declaration
Since 2015, Emirates has continued its strong support for actions to stem the illegal trade in wildlife and wildlife products, which is having devastating consequences for endangered animals and the environment in many parts of the world. In 2018, the Emirates Group also signed the Buenos Aires Declaration on Travel and Tourism and Illegal Wildlife Trade, an effort led by the World Travel & Tourism Council (WTTC) to reach a billion travellers with messages to fight the illegal wildlife trade and work with communities to develop sustainable tourism that provides livelihoods and protects wildlife. The WTTC and World Wildlife Fund are developing guidelines to eliminate illegal wildlife trafficking from the travel and tourism supply chains.
The Emirates Group has also adopted a zero-tolerance policy to wildlife trafficking and has set up training for its employees to identify and look out for warning signs of smuggled wildlife products during cargo transportation and screening. Emirates will not carry banned species, hunting trophies or any products associated with illegal wildlife activities.
Using its brand power to raise awareness around the illegal trafficking of endangered wildlife, Emirates emblazoned four of its A380s with special wildlife decals. Since then the aircraft have flown millions of kilometres across 48 cities in 29 countries on close to 6,000 flights taking this important message around the world and spurring conversation around wildlife preservation.
dnata Wildlife Conservation and Nature
dnata recently signed an MOU with the University of Pretoria in South Africa to support their research and rehabilitation projects. Under dnata4good, the partnership aims to safeguard wildlife and the environment by strengthening and enhancing research, veterinary training and awareness, increasing involvement through volunteer opportunities and ensuring needed measures are taken to care for injured animals and rehabilitate them to go back into the wild. The initiative will be partially driven by employee participation to protect fragile biodiversity in South Africa and to maintain balanced ecosystems.
Give a Ghaf
Emirates Group employees living in Meydan Heights (UAE) will be taking part in a Ghaf Tree planting event on 27 April in partnership with Goumbook. The event aims to raise awareness about the importance of conserving the living desert, with a specific focus on the Ghaf tree. The Ghaf is a drought tolerant, evergreen tree which can withstand harsh desert environments, and can be used for greening purposes whilst saving water.
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Top 10 sustainable places to stay around the world revealed
Travel is not just about seeing the wonders of the earth but understanding our impact upon it. With increasing frequency, people are looking to make the shift from “tourist” to “conscious traveler” by finding ways to maximize positive impacts on the locations they visit. Making thoughtful choices about how, when, and where you go on a vacation can make a significant difference. So, this Earth Day, travel experts analyzed over eight million traveler reviews from last year to find the key hot spots for eco-travelers.
Delving deep into sentiment, the global data showed the 10 best places to stay around the world, as reviewed by Expedia travelers. From boutiques with beehives and resorts with rainwater recycling, to grand urban retreats with solar cell power, many of these amazing places show that luxury and sustainability are not mutually exclusive.
Additionally, the experts highlighted the top countries with the best reviewed eco-conscious accommodations, with the USA topping the charts.
Top 10 eco-friendly stays
1.Sandos Caracol Eco Resort, Mexico
2.Nomad Hotel Roissy CDG, Paris, France
3.Siloso Beach Resort, Sentosa, Singapore
4.Habitat Suites, Austin, Texas
5.Pakasai Resort, Krabi, Thailand
6.PARKROYAL on Pickering, Singapore
7.The Green House, Bournemouth, UK
8.Listel Hotel, Vancouver, Canada
9.Hotel Verde, Cape Town, South Africa
10.Sherwood Queenstown, Queenstown, New Zealand
Top 10 sustainable countries around the world
1.USA
2.Mexico
3.Canada
5.UK
6.Costa Rica
7.Thailand
8.New Zealand
9.France
10.Italy
Sustainable travel is the perfect opportunity to show Mother Earth and fellow inhabitants how much you care.
1. Sandos Caracol Eco Resort – Playa del Carmen, Mexico
Situated between dense jungle and the blue of the Mexican Caribbean coast, this Rainforest Alliance-certified destination is among the highest-rated by travellers for the multitude of positive impacts it offers.
•Extensive policies governing waste management, resource consumption and natural conservation
•Opportunities for guests to engage in ecologically sustainable practices: eco-tours, cruelty-free animal interactions and beach meditation
•A commitment to the community, reflected in celebrations of local indigenous culture, on-site markets that support local artisans, and local partnerships to improve area schools
2. Nomad Hotel Roissy CDG – Paris, France
Located five minutes by car from Charles de Gaulle airport, the Nomad Hotel Roissy CDG boasts Scandinavian-inspired design, tech-enabled customisable room layouts and a mission to “to reduce the ecological impact of these buildings to a minimum, at every stage of life, from design to operation”—making it the perfect accommodation for digital nomads with green leanings.
•Rigorous standards for creation/loss of heat and a low total annual energy consumption, supported by green (living) exterior cladding, solar panels, air handling units
•Proactive efforts to neutralize water impact through use of rainwater collectors
•Use of sustainable materials, including PEFC wood, carpets made from recycled fishing nets, recycled stone and glass shower units
3. Siloso Beach Resort, Sentosa – Singapore
Just off Singapore’s south coast lies Sentosa Island, a haven whose southwest coast is the home to the Siloso Beach Resort. Steps from the sandy beaches of the South China Sea, this award-winning eco-resort has taken special care to integrate the surrounding habitat into its design by prioritizing open spaces and preserving established natural features like mature trees and flowing springs. The result? A uniquely organic take on a luxurious beach resort experience.
•200 original trees preserved (and 450 planted) on-site; landscape pool fed by underground waters and built according to natural terrain formation
•72% of the resort is open-air—and activities including cycle tours, hikes and other eco-adventures
•Operations keep ecological impacts top-of-mind, emphasizing locally-sourced foods, limited use of plastics, and reduced energy consumption
4. Habitat Suites – Austin, TX, USA
Habitat Suites, a sustainable gem in the heart of Texas’ most progressive city, boasts a 30-year track record of forward-thinking environmental stewardship. Habitat Suites has been a charter member of the Green Hotels Association since 1991—and won an Austin Green Business Leader Gold Award in 2018.
•Widespread use of alternative energy, including solar panels, solar thermal and electric vehicle charging
•On-premises organic fruit and herb gardens; clean, local and organic food options
•Use of plant-based, zero harsh chemical detergents for cleaning; bio-safe guest shampoos and detergents; hypoallergenic suites that include live potted plants and windows that open for access to fresh air
5. Pakasai Resort – Krabi, Thailand
Spa treatments, boxing and cooking classes plus plenty of space for lounging by the pool—the Pakasai Resort delivers on everything you’d expect from a tropical Thai resort, then sweetens the deal with an impressive list of sustainability efforts. “Krabi’s Greenest Resort” was the first in the area to win an ASEAN Green Hotel Award (2014).
•Resource conservation efforts include rainwater capture and greywater recycling, energy efficient lighting, biogas production and reduction of plastic use
•Careful attention given to reducing carbon emissions through waste minimization program and collaboration with the local community and local organizations
•Guests are encouraged to make their stay even greener by joining the #GreeningPakasai campaign, which incentivizes visitors to make low-carbon choices around food, transportation, linen services and local activities
6. PARKROYAL on Pickering – Singapore
With 15,000 square metres of greenery and a cutting-edge design, the PARKROYAL is equally impressive in what it does and doesn’t do. This LEED-certified masterpiece saves 32.5 Olympic-sized swimming pools’ worth of water annually and could power an estimated 680 households with the energy saved by its conservation efforts.
•Highly regulated resource consumption through employment of light, motion, and rain sensors
•Solar cells and rainwater collection mean zero-energy maintenance of the 15,000 m2 sky gardens
•Thoughtful construction processes reduced concrete (and associated waste and energy expenditure) use by more than 80%
7. The Green House – Bournemouth, UK
Equally suitable for weddings, self-care weekends and romantic getaways, every detail of this eco-hotel has been designed to help guests feel great while doing good. That ethos touches every facet of The Green House, from the building’s renewable energy production and Forest Stewardship certified, UK-crafted furnishings to the on-site restaurant’s adherence to local sourcing and high animal welfare standards—the company car even runs on bio-fuel from the kitchen’s old cooking oil!
•The use of earth-friendly cleaning products and efforts toward energy conservation
•Staff are trained in the ethos of sustainability and are encouraged to find new ways to improve the Green House’s efforts
•Environmental efforts extend to the exterior grounds, including bird and bat boxes (to provide a safe place for breeding) and rooftop beehives that produce honey
8. The Listel Hotel Vancouver – Vancouver, BC, Canada
The Listel Hotel dedicates itself to both environmental responsibility and the arts. The hotel provides a location to elevate local and international artists—including a gallery dedicated to First Nations artists from the Northwest Coast—while participating in the city of Vancouver’s “Corporate Climate Leader” program, setting an example for sustainable tourism efforts across the globe.
•Responsible food practices including membership in Vancouver Aquarium’s Ocean Wise sustainable seafood program and a commitment to offering local and sustainable food and wine
•Conservation efforts including 20 solar panels, a state-of-the-art heat capture program (reducing the hotel’s natural gas use by 30%) and water reduction and air quality programs
•Adherence to a 100% Zero Waste policy since August 2011
9. Hotel Verde – Cape Town, South Africa
“Sustainable by design, stylish by nature” is the modest motto of Cape Town’s Hotel Verde. The first hotel in Africa to offer 100% carbon-neutral accommodation and conferencing, the Cape Town Verde has earned an extensive list of international accolades (LEED Platinum certification and a 6-star rating from the Green Building Council of South Africa) for its extensive adherence to sustainable practices.
•Restoration of the surrounding wetlands now supports indigenous water-wise vegetation and a healthy population of Cape honeybees—as well as an ecotrail, outdoor gym, and eco-pool for visitor use, plus on-site edible food gardens and aquaponics
•Energy efficiencies include photovoltaic panels on the roof and north-facing facades, wind turbines, energy-generating gym equipment and geothermal heat
•Commitment to social responsibility through sustainable procurement practices, waste management and community involvement
10. Sherwood Queenstown – Queenstown, New Zealand
Sustainability and connection with nature are behind every detail you’ll encounter at the Sherwood Queenstown, a boutique hotel perched on three acres of alpine hillside overlooking Lake Wakatipu. The Sherwood operates based on the belief that “a simple respect for nature lies at the heart of any sustainable practice”. The hotel’s orchards and kitchen garden supply its award-winning restaurant; most rooms offer sweeping mountain or lake views, and all are outfitted with South Island wool blankets and locally-sourced beverages. Mornings start with optional yoga sessions, followed by hiking, mountain biking, skiing or snowboarding.
•A focus on materiality selection that integrates the building with the landscape, while employing upcycled fixtures, fittings and furnishings
•Conscious choices about energy generation—the Sherwood is one of the largest private solar installs in New Zealand and currently generates enough electricity to return surplus to the grid
•Selection of food, wine, beer, spirits, and other consumable products that are local, natural, healthy, ethical, seasonal and sustainable in their production and use
Filed Under: Press Release Tagged With: and, annual, aquarium, area, around the world, art, artisans, artists, Arts, ASEAN, association, August, Austin, Australia, award, award-winning, based, bat, BC, beach, Beach Resort, beaches, beer, best, Beverages, biking, BIO, bird, blankets, Bournemouth, boutique, boutique hotel, boxes, Breaking Travel News, breeding, building, buildings, built, Business, campaign, Canada, Cape, Cape Town, car, carbon, carbon emissions, carbon-neutral, Caribbean, Carmen, CDG, celebrations, certification, certified, charging, Charles, Charles de Gaulle, Charles de Gaulle airport, charter, China, choices, city, classes, clean up, cleaning, climate, coast, collaboration, collection, commitment, community, company, connection, conservation, construction, consumption, cooking, cooking oil, corporate, Costa, Costa Rica, council, countries, creation, culture, currently, cutting, Data, day, deal, design, designed, Destination, digital, doing, Earth, earth day, Eco Hotel, eco-conscious, eco-friendly, ecological, Edge, efforts, eight, electric, Electric Vehicle, electricity, emissions, employment, encouraged, energy, energy conservation, environmental, equipment, established, ethical, even, exclusive, expect, Expedia, experience, experts, extend, extensive, Features,, find, finding, first, first hotel, fishing, followed, food, food and wine, forest, Forward, France, free, frequency, Fresh, friendly, fruit, fuel, Garden, gardens, Gas, Gaulle, GEM, getaways, glass, Global, Globe, GO!, gold, Gold Award, good, Grand, green, green hotels, greenery, greenest, grounds, guests, handling, harsh, haven, healthy, heart, Heat, help, high, highest, hikes, home, Hospitality News, Hot, hotel, hotel award, Hotel Travel News, Hotels, house, impact, impacts, impressive, improve, in, including, increasing, indigenous, inspired, International, International Travel News, island, IT, Italy, joining, Jungle, just, keep, key, kitchen, Krabi, landscape, largest, last, leader, LEED, lies, life, light, like, Limited, list, live, Living, local, locally, located, location, locations, looking, loss, low, low-carbon, luxurious, Luxury, maintenance, Make, management, markets, materials, Meditation, member, membership, Mexican, Mexico, million, mind, minutes, mission, most, Mother, mountain, mountain biking, nations, natural, nature, neutral, New, New Zealand, News articles, North, Northwest, ocean, offer, offering, offers, Oil, Olympic, open, operation, operations, opportunities, opportunity, options, organic, organizations, original, outdoor, over, Paris, partnerships, People, Place, places, plant, planted, plants, plastic, plastics, platinum, policies, policy, pool, population, positive, Positive Impacts, power, practices, private, processes, production, products, program, programs, provides, quality, Queenstown, rain, rainforest, rated, rating, record, recycling, reduce, reduction, renewable, renewable energy, resort, Resort News, resorts, resource, respect, responsibility, responsible, Responsible Tourism News, restaurant, restoration, retreats, return, revealed, reviews, romantic, roof, room, rooms, s, safe, sandy, scandinavian, schools, sea, seafood, seasonal, seeing, selection, sensors, sentosa, Sentosa Island, services, sessions, setting, shift, show, significant, Singapore, site, skiing, sky, social, social responsibility, solar, South, South Africa, South China, Southwest, spa, space, spaces, Special, spirits, spots, springs, Square, staff, standards, Star, start, State, stay, stays, suites, supply, support, supported, supports, surplus, Sustainability, sustainable, sustainable practices, sustainable tourism, Sustainable Travel, swimming, tech, Texas, Thai, thailand, The World, through, to, top, top 10, total, tourism, tourist, Tours, town, Transportation, Travel, Travel Destination News, Travel Experts, Traveler, travelers, travellers, Travelwire News, treatments, trees, tropical, turbines, TX, UK, units, urban, USA, use, vacation, Vancouver, Vehicle, views, visit, visitor, visitors, waste, waste management, water, waters, ways, weddings, wetlands, win, wind, wind turbines, wine, won, wonders, World, World News, worth, year, yoga, Zealand, ZERO
D.R. Congo: African Tourism Board is a place to be according World Heritage Kahuzi-Biega National Park
The African Tourism Board welcomes Kahuzi Biega National Park as a new member. The Kahuzi-Biega National Park is a protected area near Bukavu town in the eastern Democratic Republic of the Congo. It is situated near the western bank of Lake Kivu and the Rwandan border.
“The African Tourism Board is a place to be, we have been undercover for long. When you search for Congo tourism, all you hear is information about Virunga or news about poacher. We want to make a difference. Let’s unite our efforts to promote the African tourism industry.”
These are the word by De Dieu Bya’Ombe, director of the Kahuzi Biega National Park.
He explains on his membership information:
Kahuzi-Biega National Park is home to more species of mammals than Any Other Site Albertine Rift. It is the second major MOST website in the area for Both endemic species and in terms of species richness. The park HAS 136 species of mammals, Including the eastern lowland gorilla is the star and 13 other primates like chimpanzees Including endangered species, red colobus monkey, and monkeys L’Hoest and Hamlyn.
• Other extremely uncommon species of the forests of eastern DRC are present aussi Such As the giant genet ( Genetta victoriae ) and aquatic genet ( Genetta piscivora ). Characteristic mammals of the central African forests aussi live in the park as the forest elephant, forest buffalo, giant forest hog and the bongo.
• The KBNP Is located in significant year endemism zone (Endemic Bird Area) for birds APPROBATION by Birdlife International. The Wildlife Conservation Society HAS compiled a list of birds to the park in 2003 with 349 species Including 42 endemic.
• Similarly, the park aussi Was Recognized As a diversity center for plants by IUCN and WWF in 1994 with at least 1,178 species listed in the high altitude area, the lower portion still remaining in inventory.
• The park is one of The Few sub-Saharan African websites Where flora and fauna transition from low to high altitude is observable. It included courses, in fact, all of the forest vegetation from 600 m to more than 2600 m, bass Moist Forest and medium altitude forest sub mountain up montane forest and bamboo. Above 2600 m to the top of Kahuzi Biega and mountains, Has Developed montane vegetation heather harboring endemic plant Senecio kahuzicus.
• The park houses aussi Generally, not Widespread vegetation Such As swamps and altitude bogs and swamp forests and riparian areas are waterlogged at all altitudes.
Due to all above specificities of the Kahuzi – Biega national park, we are looking forwards to develop eco-tourism activities and sustainable conservancy concept which are going to inspire the next generation.
Kahuzi Biega is a world heritage site created in 1970 for the main purpose of protecting low land gorillas. Kahuzi-Biega National Park is divided into two zones connected by a narrow corridor: Rainforest Mountain (Afro-montane forest gold) on one hand, and the lowland rainforest (Guinea-Congo Relatively wet) on the other hand.
It is a scarce African region where the transition entre thesis two kinds of rain forests remained largely intact. So far, over 1178 plant species have been recorded at high altitude, making it the third Albertine Rift website in terms of species richness partner after the Virunga National Park in DRC and the Bwindi Impenetrable Forest in Uganda. For cons, the lowland flora is still little known. The inventory of species endemic to the Kahuzi-Biega National Park is far from full, and we Even Discovered Many new species Belonging Mainly to the families of Balsam Orchidaceae & Purple Spurge, Araliaceae, Anacardiaceae, and many others families with one Particular species ( Fischer, 1995).
Conservation targets are the wildlife and communities at risk, and critical habitats and declining to protect. The subsidiary or auxiliary targets are a more detailed level of the target to which they are attached (parts of habitat, landscapes, media, etc.). The term key ecological attributes of the main natural characteristics of species, populations or ecosystems developed over time or as a result of natural disturbances and allow maintaining the range of conditions under which species are adapted. Furthermore, the exceptional forest cover KBNP an important carbon sink to contribute to the fight against climate change.
Talking about tourism, we offer gorilla trekking as our main attraction. Hiking, mountain accession and birds watching are complementary to the main attraction. We are proudly the only site where visitors can trek low land gorillas in the wild. We put our efforts to maintain all our tourism activities sustainable and ecological.
More information: www.kahuzibiega.org
More information on African Tourism Board:www.africantourismboard.com
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About the African Tourism Board: Top important according to an African American Tourism Expert
Drew Barrett, a Chicago based African American tourism expert and consultant, thinks the newly founded African Tourism Board(ATB) is very important and potentially valuable to the nations of Sub-Saharan Africa.
ATB will celebrate its official launch on April 11 during the World Travel Market in Cape Town and has moved to a world of attention. ( www.
The nations of Sub-Saharan Africa are very hungry for and in need of growth of their inbound international tourism business. Most, however, have a steep learning curve, over which they must overcome to achieve any measurable incremental results. Most are steeped in best practices of a bygone error of global tourism marketing if they are doing anything at all. Most are not.
Nations like Kenya, Tanzania, South Africa have significant global brand equity for leisure tourism. Others like Ethiopia, Nigeria, Ghana and again South Africa; are a compelling destination for business tourism. Yet on the extreme opposite end of the attractiveness spectrum others, due to conflict and a total lack of internal security are not in the running.
All nations of Sub-Saharan Africa with any viable tourism product are seeking to up their game, but have to reconcile a penchant, if not add to investing, and in many cases, mis-investing in energy, data +telecommunicationss, and transportation infrastructure to achieve modern global standards. They are missing there real opportunity.
The most readily available economic growth engine for all nations of Sub-Saharan Africa is their adventure, art, community, cultural, ecological (flora + fauna) and handicraft tourism products; in which they should invest in both development and marketing. The immense profit potential of such well planned and implemented investments, will return profits; which will pay for everything else.
I have two Sub-Saharan African nations, Kenya and South Africa, digress from World Class Tourism Marketers, not having a clue as to what to do; because they forsake a focus on their indigenous roots, attempting to promote being global business meeting and conference destinations; a playing field on which they cannot compete, for so many reasons.
I have just last week, submitted a comprehensive, preliminary strategic tactical concept proposal to a Northwestern Sub Saharan nation. I had developed similar proposals for three other nations. In each case, I have been working with someone who has strong connections to government decision makers; but not with any preconceived disposition toward action. In the most recent case, my contact is a division of the Ministry of Tourism.
Nigeria, a few years ago, invested in the development of a Culture and Music festival which it could market globally. The problem with some post colonial nations is, they are addicted to seeking the help of postcolonial consultant intermediaries of European and North American multinationals, for expertise. The problem is those consultants do not have the expertise necessary to enable the success of such an undertaking.
The consensus is to invest in building grand hotels, great roads, and transportation; and tourists will come. Wrong, they just end up with choking foreign debt and no tourist.
Again, the African Tourism Board, can be the way forward for the Nations of Sub Saharan Africa to be able to monetize their most readily available natural resource, as previously stated.
African Tourism Board brings to those nations both internal and external subject matter experts, professional practitioners, industry resources and massive implementation capabilities; in a unified platform which can teach the leadership of the nations of Sub Saharan Africa how to successfully market their destinations and tourism assets, to the billions of ready, willing and able international tourist.
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America’s Best Ecotourism Destinations ranked
Ranking series of “America’s Best Ecotourism Destinations” were released today.
Whether it is strolling along a beach in California or spotting alligators in the Everglades, traveling is an exciting experience. Caught up in all of this excitement though, few people stop and think about the impact they are having on the environment and the local communities they are visiting. In response to the carelessness of many tourists and money-sucking tourist magnets, a movement known as “ecotourism” is becoming increasingly popular. The staff at RAVE Reviews is a fan of both sustainable living and traveling. It just made sense to find the best Ecotourism destinations that people can sustainably visit and enjoy.
Ecotourism is essentially sustainable travel that focuses on supporting untapped natural beauty instead of massive tourist machines. No more buying overpriced souvenirs in Times Square and throwing the plastic wrapping on the ground. Ecotourism would have you animal spotting along Virginia’s Birding and Wildlife Trail, or maybe even immersing yourself in a Native American living history experience at Colorado’s Indigenous Roots LLC. This ranking plans out the perfect ecotourism road trip across the country. For convenience, RAVE also included recommendations for activities and lodging near each destination.
In determining which destinations to feature, the experts compared reviews from sources across the internet and took into account multiple factors such as the number of eco-tourist attractions in the region, availability of eco-lodging near the destination, degree of community support for ecological initiatives, and if the destination made sense in the routing of the trip.
The full list of featured destinations includes:
Appalachian National Scenic Trail, Georgia
DownEast Acadia, Maine
Hawley Earthfest, Pennsylvania
Indigenous Roots LLC, Colorado
Kasha-Katuwe National Monument, New Mexico
Lake Erie, Ohio
Omega Institute for Holistic Studies, New York
The Everglades, Florida
The Ozarks, Missouri
Virginia Birding and Wildlife Trail, Virginia
Washington D.C., District of Columbia
World Birding Center, Texas
Yellowstone National Park, California
Yosemite National Park, California
Zion National Park, California
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International SOS: Health and Travel Safety Tips for Chinese New Year Celebrations
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SPONTANEANATION with Paul F. Tompkins
Earwolf Classics
Ask Paul!
By Paul F. Tompkins, June 10, 2015 in SPONTANEANATION with Paul F. Tompkins
paul f tompkins
RichTackenberg 0
Wolfpup
At your live Largo shows (I was lucky/smart enough to attend the August recording with Tom Lennon), you introduce the improvisors before the guest. I liked how the interview with the guest was then closer to the improv, and more details from your interview seemed to make it into the story. Have you ever thought of trying that structure during the studio recordings?
To say I love the show is an understatement!
Paul F. Tompkins 736
Switching up the order of introductions/conversations has less to do with it than the live factor, I think. We've had plenty of studio eps that include lots of details form the interviews,but they don't necessarily have the same impact. Live shows are just a whole different thing. Also, the location that Tom came up with that night came from a conversation we had in the dressing room before the show even started, so there's no guarantee that any segments need to be closer together for memory's sake.
I am glad you love the show! Thank you!
My name is Erick 2
Hi, Paul
I'm wondering if you've ever heard of a podcast called Illusionoid. It's another narrative improv show but this one is focused on science fiction elements. There are 3 improvisers but occasionally they have guests (most notably they've had Colin Mochrie). If you haven't already then I think you might be interested in listening to it. If you have then you can forget I said this. That's all for now.
Partario 4
Where is the opening interview question for Andy Daly at podfest going to come from? Won't it throw off the order if it's the question from the last episode you recorded, since the podfest ep will be "released" first? This is troubling me more than it probably should!
Kickpuncher 5011
Sentient Meat
Location: Ithaca, NY
The same could be said for all of the live episodes. Sure, this one will be available live (and shortly thereafter) to more people than a typical live episode, but I don't think that's enough reason to change the approach.
But those live episodes are later released free through earwolf (in the proper order), do we know that the podfest episode will be?
I had assumed it wouldn't since unlike the largo eps, everyone has the ability to pay for these, but I don't really know so I probably shouldn't assume anything.
DanEngler 5196
Most/all of the Earwolf recordings from past LA Podfests have been released as regular episodes, albeit a few weeks later (presumably to give paid users a chance to watch them first.) That said, Paul has stockpiled enough episodes that I imagine the LA Podfest show wouldn't air until November at the earliest.
Bumpy 1673
Location: Shmocation
Why do you limit the suggestions to locations?
If you get something that's just weird that might be unworkable would you try to roll with it?
How bad would a guest have to muff a suggestion for you to tell them 'Nope. Try again.' (much more diplomatically, of course)?
Blink 1844
Location: Milwaukee
The transition sound effects have been a good part of the show, despite how often they have to be described (a necessity, of course). Have you thought of any other unique additions you could make to an improv format where everything is recorded? Like, for instance, Horatio's show has audio added in post-production. It's probably not something that works for this show, but it's just an example of a strength of this format.
A location is, I think, the fastest was to get into a story. I also just like it the best.
I believe this has been asked and answered IN THIS VERY THREAD!
I would never say never in terms of changing the elements of the show, but one thing I can tell you is, there will be no post production on this show, apart from fixing any mistaken plugs-- wrong dates, canceled shows, that sort of thing.
In terms of post-production FX, with all due respect to the great Mr. Sanz, no one is going to do it better than Superego. Of course, I might be biased.
Sorry about having to repeatedly describe the SFX and congratulations on your obviously PERFECT LIFE.
VajayjayLeno 336
Do you think the full majesty of the live shows could ever be produced as a HOWL™ Premium™ exclusive? Like in full video? Just asking as someone who lives nowhere near CA, but would spend all my baby's diaper money to see Spont Live.
I would love that. I'll investigate it. But I'd guess it's come up before and there are logistical nightmares involved.
souprman 10472
celebrity, sometimes two, that we're with
Paul if I guess the correct Smiths and Joy Division songs you sang at the live shows in 3 tries will you confirm if I'm right?
Since this information is already available online, I bet I won't!
FisterRoboto 7495
#likesanimals
Doesn't Largo prohibit filming? I feel like that was something they mentioned in the Tig documentary on Netflix. I'd LOVE to see a live SPONT recording, though. I'm sure it's totally delightful.
Largo has called a moratorium on full-on film crews coming in-- one of the last things to be shot there was the Thrilling Adventure Hour concert film-- but a live-stream setup could be far less intrusive. It's worth asking!
LizBradley 144
You might be interested in purchasing a pass to watch the archived LA PodFest show. Andy Daly's poor penmanship sent us all on an unexpected journey! Or you could wait until December...
I meant to tell you this in person, but we'll see if I can twist it into a relevant question.
Many of us here on the Internet are so happy that you're working with Nathan Diffee. From the beginning, we looked forward to his posters every week, and got to know him online. When you hired him, we were so excited, and it's been great to hear your shout-outs to him on the show. He is a great guy and a talented one, and he deserves all the good things coming to him. He's a hero to his fellow Spont/PFT fans, and it's fun to wonder what you guys will come up with next.
Now, a relevant question...
At the shows, and the poster choices: "Savannah, Georgia", "Pigeon and Friends" and what else? Do you also have the poster that is made to promote that specific live show? Like will you have THIS ONE available at the live show on October 3rd?
After the show actually happens, I'm guessing Diffee will probably make a new poster for the episode, but I guess that's more of a question for him.
Thanks, as always.
Many of us here on the Internet are so happy that you're working with Nathan Diffee.
Diffo is terrific! I am loving his episode art. And I am really enjoying his ideas and collaborating with him on the live show posters.
Yes-- at the live shows, we sell the poster for that particular show, so the one you linked to will be for sale! And wait til you see the one for November....
And wait til you see the one for November....
Thanks for the answer - can't wait to see it! I'm hoping to make it out there again before too long.
Oddbomb 1107
Location: Canada City
Would you ever consider a Spontaneanation / Drunk History crossover, just in the sense that everyone gets tipsy for the recording? If I remember correctly, Colleen Smith already suggested something like this.
Is there any way you could bring Nick Nolte with you on your next CBB appearance?
Thanks for all of the laughs, you're the best showman I know of.
AstronomicalCat 241
aka Space Puss
Location: High up
If Elves were real, do you think they'd like your show? Would you try to cater the show to them at all? Finally, is there a fictional race you're already attempting to woo with this Spontaneous Nation of yours?
P.S. I really like all of your shows and you're very funny and sometimes it's overwhelming.
JacobCrites 4976
Stolen by a Mean Crab
I'm a dumb hick from Ohio, so the only exposure I have to good improv is through podcasts (so thank you!). Prior to Spont, the only other improv-based podcast I listened to were Improv4Humans and Superego. I've noticed that the tone of the improv is typically broad and silly from the start, whereas typically with I4H and SE it starts more naturalistic and grows sillier as the game develops. Was this a conscious decision you made when thinking up the structure/tone of the podcast, or just something that happens naturally because of the vibe in the room? (This isn't a slam or anything, just an observation. I really appreciate this thread as someone who is interested in improv but doesn't have a lot of resources where I live)
Go To Topic Listing SPONTANEANATION with Paul F. Tompkins
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REMINDER AND UPDATE: REQUIREMENT FOR INSTRUCTION IN THE RESPONSIBLECONDUCT OF RESEARCH IN NATIONAL RESEARCH SERVICE AWARD INSTITUTIONAL
NIH GUIDE, Volume 23, Number 23, June 17, 1994
P.T. 44
Ethics/Values in Science & Technol
Grants Administration/Policy+
Since July 1990, the National Institutes of Health (NIH) has required
all applications for Institutional National Research Service Award
(NRSA) Research Training Grants (T32, T34) to include a description
of a program to provide instruction in the responsible conduct of
research. This requirement was announced in the NIH Guide for Grants
and Contracts on December 22, 1989 (Vol. 18, No. 45), and again on
August 17, 1990 (Vol. 19, No. 30).
With this notice, the NIH updates and reinforces the commitment to
ensure that all NRSA supported trainees are provided an opportunity
for training in the responsible conduct of research. Plans for
instruction in the responsible conduct of research will continue to
be required in all applications for institutional NRSA research
training grants. But, beginning with applications for research
training grants received on or after January 10, 1993, this
requirement will be modified as follows:
o Applications without plans for instruction in the responsible
conduct of research will be considered incomplete and will be
returned to the applicant without review.
o Every predoctoral and postdoctoral NRSA trainee supported by a T32
or T34 institutional research training grant must receive instruction
in the responsible conduct of research.
o Plans that incorporate instruction in the responsible conduct of
research for all graduate students and postdoctorates in a training
program or department, regardless of the source of support, are
particularly encouraged.
o Although the NIH will not establish specific curriculum or format
requirements, all programs are strongly encouraged to consider
instruction in the following areas: conflict of interest,
responsible authorship, policies for handling misconduct, policies
regarding the use of human and animal subjects, and data management.
o Plans must address: the subject matter of the instruction, the
format of the instruction, the degree of faculty participation,
trainee attendance, and the frequency of instruction. A rationale
for the proposed plan of instruction must be provided.
o Progress reports on the type of instruction provided, topics
covered, and other relevant information such as attendance by
trainees and faculty participation must be included in future
competing and noncompeting applications.
The procedures for the review of the plans for instruction in the
responsible conduct of research will be as follows:
o At initial review, one or more reviewer(s) will be assigned to
evaluate the plan for providing training in the responsible conduct
of research.
o The plan will be discussed after the overall determination of
merit so that the quality of the plan will not be a factor in the
determination of the priority score.
o The assessment of the plan will include consideration of the
appropriateness of the topics, the format, the amount and nature of
faculty participation, and the frequency and duration of instruction.
Plans will be judged either acceptable or unacceptable.
o The plan and its acceptability will be described in an
administrative note in the summary statement.
o Regardless of the priority score, applications with unacceptable
plans will not be funded until a revised, acceptable plan is provided
by the applicant. The acceptability of the revised plan will be
judged by staff within the awarding component at the NIH.
The contact for general information about this policy is:
Dr. Walter T. Schaffer
Director, Research Training and Special Programs Office
Building 31, Room 5B44
Bethesda, MD 20892
Telephone: (301) 496-9743
Questions regarding a specific training program or grant application
should be directed to the appropriate NIH Institute.
Return to 1994 Index
Return to NIH Guide Main Index
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A landmark photography project
MARY-ELLEN McTAGUE: chef
greatermancunians Jul 19, 2017 Nov 26, 2019 Culture, Food, Manchester
Photography by Yasmin Carter
Words by Harry Potts
Mary-Ellen McTague is an award winning Manchester based chef with a passion for locally sourced food.
Bury born, Mary-Ellen developed a passion for cooking, when working in the kitchen of the Manchester Roadhouse making food for touring bands. Keen to gain more experience, she became the first female chef at Michelin-starred country house hotel Sharrow Bay.
Award winning chef, Mary-Ellen McTague
After a short period working in America, Mary-Ellen joined The Fat Duck in 2002 and progressed from the pastry section to become Sou Chef under Heston Blumenthal. She remained there for four years before opening her own restaurant Aumbry in Prestwich in 2009. Despite being set in an intimately small location, Aumbry quickly became much loved and critically acclaimed with The Guardian describing the restaurant as a “miracle of Lilliputian industry.”
Mary studied under Heston Blumenthal
After the closure of Aumbry in 2014, Mary-Ellen has been involved in a series of city centre ventures including a pop up restaurant called 4244 in the Northern Quarter, Head Chef for the ‘pay as you feel’, Real Junk Food Project (now Project Director) and enlisted to give Manchester Art Gallery’s cafe a major overhaul. Mary-Ellen is currently getting rave reviews for her latest venture The Creameries located in the Chorlton area of the city
Mary-Ellen has appeared on two series of the BBC series Great British Menu, in 2013 and 2014. She is also regularly interviewed on BBC television and radio and has written a food column for The Guardian newspaper.
Relaxing in Albert Square
Yasmin and Mary-Ellen
Student reflection: Yasmin Carter
“Working with Mary Ellen was a fantastic and rewarding experience. It has developed my confidence and made me realise the value of getting to know your client and making them feel comfortable before a shoot. I hope to continue to develop these important skills as my photography career progresses over the coming years.”
Mary is an enthusiastic contributor to The Manchester Food and Drink Festival
Mary and her restaurants have won a number of awards. In 2012 Aumbry won Restaurant of the Year at the Manchester Food and Drink Awards and the following year she was named Chef of the Year. In 2014 McTague won the Cheshire Life and Lancashire Life Chef of the Year.
Mary has ambitious plans for a flagship city centre restaurant
© All images – The Manchester College (unless otherwise stated)
https://en.wikipedia.org/wiki/Mary-Ellen_McTague
http://manchesterartgallery.org/visit/cafe/
Aumbry, Bury, Chef, Mancunian, Mary-Ellen McTague, Restaurateur
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Next QUBEK: street artist
Published by greatermancunians
View all posts by greatermancunians
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You are here: Home Page > Arts & Humanities > Literature > Literary Studies - Poetry & Poets > A Map of Misreading
5-5/16 x 8 inches
Bookseller Code (06)
A Map of Misreading
In print for twenty-seven years, A Map of Misreading serves as a companion volume to Bloom's other seminal work, The Anxiety of Influence. In this finely crafted text, Bloom offers instruction in how to read a poem, using his theory that patterns of imagery in poems represent both a response to and a defense against the influence of precursor poems. Influence, as Bloom conceives it, means that there are no texts, but only relationships between texts. Bloom discusses British and American poets including Milton, Wordsworth, Shelley, Keats, Tennyson, Browning, Whitman, Dickinson, Stevens, Warren, Ammons and Ashbery. A full-scale reading of one poem, Browning's "Childe Roland to the Dark Tower Came," represents this struggle between one poet and his precursors, the poem serving as a map for readers through the many versions of influence from Milton to modern poets.
For the first time, in a new preface, Bloom will consider the map of misreading drawn by contemporary poets such as Ann Carson and Henri Cole. Bloom's new exploration of contemporary poetry over the last twenty years will illuminate how modern texts relate to previous texts, and contribute to the literary legacy of their predecessors.
Harold Bloom is Sterling Professor of Humanities at Yale University, Berg Professor of English at New York University, author of more than twenty books including The Anxiety of Influence, The Western Canon, Shakespeare: The Invention of the Human, The Book of J, and the forthcoming Genius.
"The sincerity of this book...the sheer care for poetry which governs both this work and its predecessor, is unmistakable and most impressive."--The New York Review of Books
"Bloom is the most rare of critics. He has what seems to be a totally detailed command of English poetry and its scholarship.... Because of his entirely gripping theoretical passion his readings are almost unparalleled in skill and thematic nuance."--The New York Times Book Review
The Anxiety of Influence
Rilke's Sonnets to Orpheus
Hannah Vandegrift Eldridge and Luke Fischer
Apparitions of Asia
Josephine Park
A Mind Apart
Mark S Bauer
Rhyme's Challenge
David Caplan
Imaginative Transcripts
Willard Spiegelman
The Art of Poetry
Shira Wolosky
Genius of Shakespeare
Jonathan Bate
Nations of Nothing But Poetry
Adverse Genres in Fernando Pessoa
K. David Jackson
Ideographic Modernism
Guilty Creatures
Dennis Kezar
The Oxford Handbook of Modern and Contemporary American Poetry
Cary Nelson
Arts & Humanities > Literature > Literary Studies - Poetry & Poets
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Posts Tagged ‘We Like We’
Track Premiere: We Like We ‘Someone told me I was Paradise for you’
We are delighted to premiere the new single ‘Someone told me I was Paradise for you’ from the gifted Copenhagen-based quartet We Like We. The gorgeous new sonic creation is the first material since the band’s critically acclaimed debut album ‘A New Age of Sensibility’ (released in late 2014). The highly anticipated single is released tomorrow, 1st September 2016.
Copenhagen-based quartet We Like We comprise the gifted talents of Katrine Grarup Elbo (violin) Josefine Opsahl (cello) Sara Nigard Rosendal (percussion) and Katinka Fogh Vindelev (voice). All four members are classically trained, but each share a desire for exploring, experimenting and shaping a unique sound of their own, as reflected in their diverse musical influences. The group’s first live performance took place at FROST festival in Copenhagen in February 2013: a unique double-bill concert with Efterklang. We Like We have collaborated with an array of musicians and projects in the past: Efterklang; Julia Holter; Mew; Sofia Gubaidulina; The Danish National Symphony Orchestra, to name but a few. We Like We’s debut album ‘A New Age of Sensibility’ is available now on The Being Music.
“This single is one of the results of our work over the past six months. We have had a close collaboration with sound engineer Marc Casanovas (NorCat Lyd) with whom we have explored sound, space and different ways of recording”.
Someone told me I was paradise for you is the endless mantra that is whispered in to your ear during the late hours of a dark blue summer night. It is four individual voices and reflections braided together as a unit in the depths of the collective unconsciousness.
From the opening dream-like pulses of delicate percussion – beginning with two gongs before soft ripples of vibraphone effortlessly melds together – We Like We’s brand new recording invites the listener deep into a labyrinth of fragile beauty and encapsulating dreams. The ambient works of Harold Budd lies somewhere in the ether of these burning flames, wherein a tenderness and stillness of night radiates with each and every meditative heart-beat. Soon, achingly beautiful instrumentation of violin is carefully added, evoking the glimmering rays of hope across cascading skies: dapples of light flicker along the horizon. The modern-classical soundscapes and divine instrumentation conjures up the timeless sound of the prestigious Touch or Type labels with the spirit of Peter Broderick, Sylvain Chauveau and Hildur Guðnadóttir
At the half-way point, the mesmerising voice of Katinka Fogh Vindelev whispers directly to one’s mind’s eye. Like a bird in full-flight, these four combined elements of strings, voice and percussion soars majestically with unlimited possibilities of discovery, exploration and chance. The mantra-like phrases sung by Vindelev transports the listener to the poignant, dream-like fantasies of Kazuo Ishiguro’s master novels or the otherworldly realm crafted by Kafka. This sublime tapestry of gradual blissed-out tones reveals inner-most truths and awakens a myriad of feelings and emotion. The compelling, ambitious and sublime new single is nestled nicely amidst the avant-garde, modern-classical and luminaries such as Scott Walker (‘Tilt’ era) and L.A’s Julia Holter and ‘Parallelograms’-era Linda Perhacs.
Released on The Being Music 2016, www.thebeingmusic.com
https://www.facebook.com/WeLikeWe/
Posted in First Listen
Tagged with Efterklang, Josefine Opsahl, Julia Holter, Katinka Fogh Vindelev, Katrine Grarup Elbo, Sara Nigard Rosendal, The Being Music, We Like We
Mixtape: Just Like Anything
Just Like Anything [A Fractured Air Mix]
https://www.mixcloud.com/Fractured_Air/just-like-anything-a-fractured-air-mix/
01. We Like We ‘I Began To Fall Apart’ [The Being Music]
02. Sufjan Stevens ‘No Shade In The Shadow Of The Cross’ [Asthmatic Kitty]
03. William Ryan Fritch ‘_a renewed sense’ [Lost Tribe Sound]
04. Mute Forest ‘Volcanoes Flowing’ [Lost Tribe Sound]
05. Kenny Burrell ‘Chitlins Con Carne’ [Blue Note]
06. Bert Jansch ‘The Blacksmith’ [Charisma]
07. Ryley Walker ‘Primrose Garden’ [Dead Oceans]
08. Jackson C. Frank ‘Just Like Anything’ [Columbia/Castle Music]
09. Peter Broderick ‘Red Earth’ [Bella Union]
10. Colin Stetson & Sarah Neufeld ‘The sun roars into view’ [Constellation]
11. Colleen ‘Captain Of None’ [Thrill Jockey]
12. Sebastian Mullaert ‘Lat Björkarna Vissna’ [Mule Electronic]
13. Hauschka ‘Pripyat’ [City Slang/Temporary Residence]
14. Noel Ellis ‘Dance With Me’ [Summer/Light In The Attic]
15. Augustus Pablo ‘Dub Organizer’ [Kaya/Tropical]
16. Calexico ‘Cumbia De Donde’ [City Slang/Anti-]
17. Batha Gèbrè-Heywèt ‘Ewnet Yet Lagegnesh’ [Manteca]
18. Tape & Bill Wells ‘Fugue 3’ [Immune]
19. Bill Wells & Aidan Moffat ‘We’re Still Here’ [Chemikal Underground]
The copyright in these recordings is the property of the individual artists and/or their respective record labels. If you like the music, please support the artist by buying their records.
To follow Fractured Air you can do so on Facebook HERE, or Twitter HERE.
Tagged with Aidan Moffat, Anti, Asthmatic Kitty, Augustus Pablo, Batha Gèbrè-Heywèt, Bella Union, Bert Jansch, Bill Wells, Blue Note, Calexico, Charisma, Chemikal Underground, City Slang, Colin Stetson, Colleen, Constellation, Dead Oceans, Hauschka, Immune, Jackson C. Frank, Kenny Burrell, Lost Tribe Sound, Manteca, Mute Forest, Noel Ellis, Peter Broderick, Ryley Walker, Sarah Neufeld, Sufjan Stevens, Tape, The Being Music, Thrill Jockey, We Like We, William Ryan Fritch
Fractured Air 34: In This Place (A Mixtape by We Like We)
https://www.mixcloud.com/Fractured_Air/fractured-air-34-in-this-place-a-mixtape-by-we-like-we/
01. Gustav Mahler ‘Symphony #5, 4th Movement, Adagietto, Sehr Langsam (with The Berlin Philharmonic and Simon Rattle) [EMI Classics]
02. Jordi Savall ‘Ductia’ [Astrée Auvidis]
03. Ligeti György ‘Hungarian Rock’, Barrel organ performed by Pierre Charial [Sony Classical]
04. Joni Mitchell ‘The Last Time I Saw Richard’ [Reprise]
05. Martin Lohse ‘In Liquid’ 1. movement [Dacapo]
06. Feist ‘The Bad in Each Other’ [Arts & Crafts]
07. Marius Neset ‘Birds’ [The ACT Company]
08. Dmitri Shostakovich ‘Song of Ophelia’ from Seven Romances on Poems by Alexander Blok Op. 127
09. Stravinsky ‘Concertino for String Quartet’ [Sony Classical]
10. Per Nørgård ‘The Gentle, The Penetrating’ from I Ching [BIS]
11. Julia Holter ‘City Appearing’ [Domino]
12. Hans Abrahamsen ‘Schnee, Canon 2a: ‘Lustig spielend, aber nicht zu lustig, immer ein bisschen melankolisch’ [Winter & Winter]
13. Quadron ‘Jeans’ [Plug Research]
14. Leonard Cohen ‘Famous Blue Raincoat’ [Columbia]
15. Maurice Ravel ‘La Valse’ [Columbia Masterworks]
16. Tenniscoats ‘End Of The Day, Slight Hunger’ [Room40]
17. Maria Callas ‘Tu Che Di Gel Sei Cinta’ (Turandot) [EMI, Columbia]
18. Franz Schubert ‘String Quintet in C Major’ D. 956, 2nd Movement, Adagio [Deutsche Grammophon]
19. Kuku Sebsebe ‘Feqreh Beretabenye’
20. Tys Tys ‘In This Place’ [Loretta Records]
21. Isao Tomita ‘Clair De Lune No. 3’ [RCA]
‘A New Age of Sensibility’ is out now on The Being Music.
http://welikewe.com/
http://thebeingmusic.bandcamp.com/
Tagged with Josefine Opsahl, Katinka Fogh Vindelev, Katrine Grarup Elbo, Sara Nigard Rosendal, The Being Music, We Like We
Step Right Up: We Like We
Interview with We Like We.
“How many times does life actually evolve as anticipated? There is something extremely beautiful about these processes and transformations.”
—Katinka Fogh Vindelev
Words: Mark Carry
We like We is an experimental performance and sound quartet based in Copenhagen, Denmark. Encompassing worlds of neo-classical, experimental pop and avant-garde soundscapes, the highly promising and gifted quartet comprises of Katrine Grarup Elbo (violin) Josefine Opsahl (cello) Sara Nigard Rosendal (percussion) and Katinka Fogh Vindelev (voice). All four members are classically trained, but each share a desire for exploring, experimenting, jamming and shaping a sound of their own.
Expanding their inspiration and influence from the classical roots We like We makes music driven by intuition and playfulness. I feel a lovely parallel exists between the Danish quartet’s highly-evocative and intuitive compositions and Iceland’s Amiina such is the unwavering beauty and utter magic the masterful musicians create with each sacred note. Through their collaborative compositions, We like We creates music that travels beyond the grid of genres. The band’s debut album ‘A New Age of Sensibility’ contains a kaleidoscope of enchanting sounds from the rhythmic pulses of ‘Anticipation’; spellbinding intermezzi capturing moments of divine transcendence (‘Tango’ and ‘I Began To Fall Apart’) and multi-layered choral patterns interwoven with immaculate instrumentation of strings and percussion (‘The Sound Of My Own Voice’).
The group’s first live performance took place at FROST festival in Copenhagen in February 2013: a unique double-bill concert with Efterklang, playing on top of a 1400-ton heavy diesel engine. Lead singer Katinka Vindelev has toured the world with Copenhagen’s Efterklang in addition to being in the choir for U.S. luminary singer-songwriter Julia Holter. Furthermore, Vindelev’s solo project of I am now offers an invaluable insight into an incredible talent. Violinist Katrine Elbo has performed with Danish artists Rasmus Seebach, Mew and Sanne Salomonson as well as a host of others (including The Danish National Symphony Orchestra). Percussionist Sara Rosendal has been an integral part to various Danish orchestras like DRUO, DRSO and The Royal Danish Orchestra. Josefine Opsahl (cello) has worked with a wide array of composers, most lately with Russian composer Sofia Gubaidulina.
Congratulations on the stunning debut album, ‘A New Age of Sensibility’. One of the striking aspects of the debut record is the sheer range of styles and musical traditions; at once it feels a beautifully realized fusion of modern-classical and pop music. Firstly, please discuss the writing process for these musical compositions? I can imagine certain pieces such as ‘The Sound of My Own Voice’ and ‘Tisina’ took quite some time to come to completion?
Sara Nigard Rosendal: Thank you for the kind words. All of our music emerges from a place of curiosity and playfulness. In the making of this album we had long jam-sessions that we recorded. We then listened to these and found some interesting themes or sounds that we tried to develop. We have worked with different dogmas in order to always expand the scale of what each of our instruments can do. None of the music is written down and there is always a touch of improvisation when we play. We like it that way, because it keeps the tracks alive.
Katinka Fogh Vindelev: This album has evolved slowly within a period of 2 years. Creating the music after getting invitations from two different progressive festivals in Copenhagen. Firstly FROST in February 2013 and later same year the experimental Wundergrund Festival. So instead of rushing into a studio, we’ve shaped and composed the music with a live concert mindset so to speak, cutting into the core of what we as a group are capable of playing and wanting to express together.
SNR: ‘Tisina’ means Silence and was an attempt to make a track that dwells on simple phrases and sounds and then create a state of meditation. It became very clear, however, that in the deep of silence there are a few demons as well. This was not something we planned – it just happened. It was not really a hard piece to make, it just requires the right state of mind and a good sense of reacting and communication.
KFV: ‘The Sound Of My Own Voice’ was a more complex composition yes, but as we’re always on the lookout for the essence of our ideas, it slowly revealed itself as repeating patterns slightly out of sync, each instrument representing an individual voice, explaining the title as well ‘The Sound Of My Own Voice’.
In terms of the instrumentation, there are gorgeously crafted arrangements throughout the record, for voice, strings and percussion also. I would love to gain an insight into your classically rooted backgrounds? Each member clearly brings their own unique vision to this special record and clearly, a deep connection is formed between the members.
SNR: We are all studying at the conservatory. Josefine and Katrine (cello,violin) are currently doing their masters at the Royal Danish Academy of Music. Katinka (voice) has a BA degree in classical voice and is currently doing her Masters in Electronic Music and Sound Art alongside private singing lessons in Copenhagen and Berlin. I have a BA from the Royal Danish Academy of Music and I am currently studying my masters in the music academy in Malmö, Sweden. We are all very happy to undergo this education. It gives us a high technical level on our instruments that then provides freedom to express ourselves. Having the entire music history as a background when creating music, is extremely helpful.
I would also love for you to recount your memories of forming We Like We? It’s fascinating (and very fitting) that your first live performance took place at a festival in Copenhagen alongside Efterklang in 2013. You all must have fond memories of this particular concert.
KFV: It took us about a year before we met Sara, so We like We was founded by Katrine [Grarup Elbo], Josefine [Opsahl] and I in August 2012 collaborating with an electronic musician, who happened to be my sister. Due to a life changing event, including the birth of my wonderful niece she pulled out shortly after our first concert and We like We continued for a while being a trio. This was an important transition, realizing that we wanted to create all the electronic layers ourselves as a natural expansion of our acoustic instruments instead of having a fourth member with a non classical background effectuating us. One day in the middle of an improvisation session I desperately grabbed a pair of claves and it became crystal clear to everyone in the room, we needed a percussionist. (Haha) Luckily Sara, who was already a friend of Katrine and Josefine’s, had common ideas and courage and joined We like We in the late Summer 2013, completing the band.
SNR: There is definitely a unique chemistry between the four of us. Each of us really needed the platform that We like We is. We all needed to do something more than what we would get from our schools. We wanted to be a part of the initial phase of the creative process – to be more than interpreters.
KFV: Regarding our first concert alongside Efterklang in February 2013, it was of course an extraordinary event for us. It felt like the beginning of something very unique, That night we performed on top of a 1400 ton heavy Diesel engine, wearing handmade costumes, that we designed ourselves and we had even hired a light designer. Liberating, personal and inspiring at the same time. I’ve been touring with Efterklang for a couple of years (singing and playing keys) alongside starting up with We like We back in Copenhagen, so we were already closely connected personally and professionally. Efterklang have curiously followed us from the very beginning, supported us, showing up at our concerts etc. Such an acknowledgement from a band, that is known for taking quite some musically risks themselves, does of course mean a lot to us.
My current favourite must be ‘The Sound Of My Own Voice’. It’s such an utterly captivating composition with intricate string arrangements and stunningly beautiful choral patterns. Please discuss the construction of this particular composition? I wonder did the words and voice parts come first or was it the cello and violin parts? I just love the dynamic, and how the piece gradually unfolds (and blossoms) before your very eyes.
SNR: ‘The Sound of my own Voice’ was supposed to be a strong proclamation of the right to be an individual. In the case of this particular track, the message came before the lyrics and the music. However, we discovered that there is a lot of pain and vulnerability in saying that you only need yourself. It is a battle between individualism and communion… ‘The Sound of my own Voice’ is a track that has had different shapes before the album-version, where we have worked with different melodic patterns played displaced. It becomes a kind of ‘free polyphony’.
I love the sequencing of ‘A New Age of Sensibility’ where several short passages are inter-woven with the more lengthy pieces. For example, ‘I Began To Fall Apart’, despite it being just over one minute in duration, a spectrum of emotion ascends into the forefront of your heart and mind. Was it a conscious decision to include shorter pieces (which also serve wonderfully as interludes) on the album?
SNR: We have thought of the shorter pieces as intermezzi (we mostly use classical terms when talking about music, because that is the language we know). When in the practice room, we would say ‘we need some ginger’ – something to ‘rinse the mouth for new flavours’. It was conscious that some pieces would be short and some long and that some pieces would only involve one or a few of us (‘I’, ‘Wakey Wakey Beast’, ‘Tango’…). We wanted the entire album to be one long narrative but for each track to still tell a story in itself.
The album was mixed in collaboration with sound artist Jacob Kirkegaard. Was there a stage in the music-making process that proved most challenging for you? Also, during the recording sessions themselves, was it a case that happy accidents would occur naturally that would lead to sketches or ideas of a song?
KFV: It was quite an intense but super smooth recording session. 11 tracks in 3 days back in February 2014 at the former National Danish Radio’s epic studios in Copenhagen. Magical almost, suddenly being in a studio, experiencing how we nailed a lot of the tracks in first take. We obviously had common visions. Recording all at once, giving the album this unpolished live touch that I find very compelling.
Having Jacob Kirkegaard on board, was a fine addition to the post-production, as he has such good ears, specialized in mainly unheard sounds. As he is also my partner he and I spent all summer in NYC on an artist in residency programme, working sporadically on the mix from April sending it back and forth across the Atlantic, for the other’s to give feedback. It turned out to be quite a time-consuming and challenging process while our music demands a lot of shaping and balancing, the instruments in between, being super dynamic, consisting of a group of four equally important voices. But it was worth the effort, of course and we wrapped up the final mix by the end of August.
SNR: Working with acoustic instruments alongside a sometimes heavy effectuation can be challenging, or at least it can be time-consuming to get the balance right. There were many magical moments. I remember that the track ‘Unite Me’, we really nailed first take. When we listened to it, right after recording, it was a complete feeling if unified transcendence. We all cried.
‘Anticipation’ conjures up the timeless sound of Steve Reich’s ‘Music For 18 Musicians’ with its sublime rhythmic pulse and compelling arrangements. I would love for you to discuss the various parts to this particular composition.
SNR: We are big fans of Reich so it is nice to be associated with him. ‘Anticipation’ is one of the more energetic pieces on the album and definitely is inspired by minimalistic pulsating rhythm. This helps underline the title as well.
KFV: We wanted to work with an often experienced consequence of anticipation – at least according to us. You are expecting something. You are eager. You are pulsating from excitement. You are narrowing down your experience of what is actually happening, overshadowed by your wishes, your anticipation, instead of staying connected and true to the moment. And suddenly, bang, reality hits you. You are out of breath.
We found it interesting to work with this sort of unexpected collapse. Illustrated by a hectic rhythm suddenly dissolving, breaking down, and turning into a slow tango – out of nowhere. How many times does life actually evolve as anticipated? There is something extremely beautiful about these processes and transformations.
In terms of inspiration and musical influences, please discuss your most cherished composers and artists? Also, what are your earliest musical memories?
SNR: One of the biggest and also early musical memories is listening to Per Nørgårds I Ching (solo percussion) when I was about eleven. That was when I realized what music could really do. Especially the third movement including a kalimba was mesmerizing to me. My earliest memories is of my father playing the guitar, I think.
KFV: I was very much into Chopin as a kid, but who wasn’t? It’s so catchy and soulful at the same time! Now I listen to all sorts of music and sound. I easily get bored when it comes to mainstream music, classical as well as pop/rock, it’s just too predictable. Silence is great though. I just worked with Julia Holter, and I think she is such an interesting composer. I love when artists manage to create catchy music with a twist. That’s a true skill. Who else… Terry Riley, John Cage, Schumann and Kuku Sebsebe.
Posted in STEP RIGHT UP
Tagged with A New Age of Sensibility, Efterklang, Jacob Kirkegaard, Josefine Opsahl, Katinka Fogh Vindelev, Katrine Grarup Elbo, Sara Nigard Rosendal, The Being Music, We Like We
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Games & Design »
RM[XP/VX/MV] and Game Design »
Screenshot Thread
Author Topic: Screenshot Thread (Read 211329 times)
Legacyblade
発行所は頑張って下さい!
Mod-Suspect
Current Mood: playful
Re: Screenshot Thread
Well here's my screenie.
It's one of the skills " " unleashes in the prolouge, when surrounded by a bunch of enemies. Needless to say, they die, (the purple tint is because of the attack)
@Aska:
Very nice, I like the concept. The sparkles are pretty appropriate to the setting and adds a nice touch. I'm not sure if that fog is fitting though, but that's kind of a personal opinion. It may be better to carve out an empty space from the flowers in the middle for the statute by the way.
@Legacy:
Lol, did Kim Jong-il drop a nuke there? Nice effect, must be a hefty animation pic if it's fully animated.
Sleepy Weasel
Weasels!
@Askalon - I like the map, although the "palm tree" sort of shadow on the water looks a little funny, with so little amount of trees near the water
(Or maybe you have a canopy over the map that we can't see)
@Legacy - Great job! You can't have any good game without a big explosion that looks like a great map, although it's hard to tell with a big purple cloud in the center of the screen
This is a screen from my new game Hawk eyes, maybe I'll post a thread up on this forum :reivsmile: but for now it stays on my computer
Well here's my screen, it has two because it's an interior scene during a cut scene, one has the text and the other doesn't
With text:
Without text
zekallinos
@Askalon
What is the fog actually is supposed to represent? I can't really image anything in that shape. What mood is this map supposed to convey, in your game context?
Also, for the middle island, it's rectangular shape makes it look a little out of place. Try considering a square or fat-cross shape, so it feels more balanced on all sides. Another little detail is the three flowers that are lined up on the bottom, a little too symmetrical in this case. It is still a beautiful map though.
Yay for flashy animations.
@Sleepy
The mayor, a respectable and mature man, looks like a kid with a fake mustache and puppy eyes. Use another set of eyes of facemaker. It's brown color doesn't seem to fit so much with his hair either. The map, being all rectangular, doesn't feel very dynamic room-wise. The people in it does, though. You can consider cutting part of the stage, since it would practically not be entirely used (stages are more square-ish).
soranokira
Current Mood: bored
@sleepy: sure looks like there are a lot of unnecessary stuff on the stage, after all I thought most of the time stages are kept clean and neat?
@askalon: I prefer circular islands =X anyway it does feel out of place since it's shaped so perfectly rectangular...
meh, random comments from someone who knows nuts about RPG-making =P
The wind will cease to be one day, and as I pass, what marks remain?
Graduation is not the end, we'll still be friends from here on out
@Sleepy:
Aye, it's pretty tricky to do old-looking faces with facemaker. I think changing the face and putting in some slimmer eyes then lift them up a bit may help. I think it may be better to shrink the room a bit, that way it's easier to fill it up without looking too blank. I like how you're using the table tile as a stage, very creative! :reivsmile:
Another Lyra's Melody title screen ss, more refined this time:
« Last Edit: April 07, 2009, 05:43:32 PM by legacyblade »
HarryE
Fall in a more hard-boiled manner
At last, I've continued some work on LoZ, kay. And I've got some lovely overworld for you.
WARNING: This is a very big file.
http://www.quintessence-tbv.com/harry/FatenoCliffside.jpg
Thanks again, Reives!
That's a very small community in the eastern part of the map. Goblins who have abandoned Keseenth have fled and made their homes in the mountains.
I wouldn't count this as a "proper" town. I never really intended it to be. It's just a stopping-off station because there's a dungeon nearby. All that's in the caves are an Item shop, a weapon shop, an Inn, and a main cave. A sort of "Mayor's house" if you will.
« Last Edit: February 05, 2009, 06:09:46 AM by HarryE »
It does look like the pic crashed halfway during upload. But there's isn't anything else at the bottom right? The community is there after all.
Well, it certainly is above the average cliff-side map. I really like how smooth the cliff blends into the water - is it animated? At some places (left) you use grass though. Not that it's bad, but it's often so thin it looks awkward. You could make it larger or edit the tiles so that the water is at a relatively equal distance from the cliff (when it's horizontal it's much thinner than at curves).
man I'm going to have fun walking all over the place.
looks laggy like what path said.
and, woot horsey. I see some bad-ass looking monsters.
what's with the holes though?
I suppose now isn't a good time to mention that that's actually split into three different maps. That's why it looks like it's partially loaded in the bottom right and top left.
Fallatham Edge
@zeka: No, the cliff is not animated. And the thing with the grass is partially intentional, because of that little spit of land there in the middle. I suppose I should merge it better somehow.
@Sora: Those little holes are meant to be makeshift windows.
lol quintessence
Quote from: HarryE on February 05, 2009, 01:51:38 PM
It might be a better idea to put in windows from an RTP town in or something, it's not really convincing as it is now. Creative, per se, but not immediately recognizable. At first I thought they would be holes for some kind of "dodge the falling rocks" minigame.
I recently discovered that I was capable of sending coins to myself, and exploiting this is surprisingly entertaining.
But again, I doubt goblins would use window.
How about make some of the windows animated so one in a while a citizen sticks his head out?
Nessiah
I'll post mine ^w^
at first glance, it looks a lot like Alter A.I.L.A, even the poses are the same (at least, in battle)
even the bg looks like the final battle where the main guys battle with A.I.L.A, space-like.
and @ Harry:
they don't really look like windows >_< besides, don't you think there are way too many windows?
and strangely enough, I don't see any caves that can lead to the other cave to get the chest, does it have to do with that door-like portal thing?(middle of map)
~True Remembrance~
@Harry: Whoa, this IS a huge map. The three maps are already huge. Most have been a lot of work. It think it a lot of fun just to walk through the map(s). They look very good, really.
@Nessiah: Very interesting. Reminds me of very old games (Jump'n'Run etc.). The panorama makes a good effect. Nicely done.
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Posted on December 20, 2018 December 20, 2018 by Colleen Vincent
THE BATMAN WHO LAUGHS / FANTASTIC FOUR / DAUGHTERS of the DRAGON / SHAZAM! / SELF-MADE [Reviews]: Merry X-Men!
The Batman Who Laughs #1 – DC Comics
Lance “Apostle” Paul
Instagram @The.TravelingNerd
The Batman Who Laughs #1 by Scott Snyder (Dark Nights: Metal) and Jock (Wytches) is a ton of different genres all wrapped into one. We start with another flashback on young Bruce growing up before his parents passed, a bat pedal to the metal high octane chase scene reminiscent of Christopher Nolan and then horror themed suspenseful third act. Snyder and Jock masterfully craft a telling story with intimate repercussions. Much different than Snyder’s much bigger Metal; but the longtime Batman scribe is always at the top of his craft when the repercussions are high but the story has on a tighter focus. Jock’s artwork is reminiscent of a cinematic eye, with the rapid pacing of a Fast & Furious sequel. The Batman Who Laughs #1 is a stellar first issue and has me excited for the rest of the mini series. 4/5 Laughing Robins agree.
-Lance Paul
Fantastic Four: Wedding Special #1 – Marvel Comics
“Reverend” Ryan Ford
@nayrdrof
Well True Believers, it looks like it’s finally happening for realsies this time — Blue-Eyed Ben Grimm is marrying his blind beloved, Alicia Masters. With promises that alien abductors or imposters (I’m looking at you, Skrulls) are nowhere to be found and super villains are super taken care of, the FF can make preparations for another addition to their Fantastic Family in what would be a wedding for the ages. And, like every wedding I’ve ever been to, some things work flawlessly, some things do not. With out further ado, let’s skip the formalities and get down to business.
The issue is broken up into three separate stories with three separate teams working on the final product. To make a comparison, it’s like when the Simpsons do a Valentine’s Day episode based on the Treehouse of Horror format. Individual stories that tie into a larger narrative, yet not necessarily the cream of the crop, if you take my meaning. Essentially, the general concept comes across as “meh”, yet the dialogue is Fantastic. Between the awkwardness of Johnny Storm running into several ex-girlfriends before a bachelorette or the Ever-Loving Thing proving he has the biggest heart in all of Earth 616, the characterizations are spot on. No matter how little the screen time, every character has an opportunity to express their core values – what makes them uniquely who they are. Likewise, the artistry accentuates insight by careful framing and a dynamic sense of motion – with the lone exception of the Cathy-like Puppet Master recap.
By and large, the issue was merely okay. However, the sum of the parts far surpasses that of the whole, making this an entry that is enjoyable if not memorable. One parting point of criticism is the lack of one Mr. Reed Richards. As someone vying to portray him on the silver screen (this is not a joke, I’m actively campaigning to be the next Mr. Fantastic), his presence was missed. Nevertheless, the plethora of Easter eggs and fun nods made up for his absence. 3/5 Bibles.
-Ryan Ford
Felipe “The 3rd Deacon” Crespo
@F7ovrdrv
Self/Made #1 – Image Comics
Hate it when an ending ruins it. Let’s start with the art. Eduardo Ferigato‘s linework is good. Nothing you’ll text your friends to look into because of how great it is, but you won’t roast it like offerings from our strap lord and pouches savior, Rob Liefeld. But Matt Groom‘s story is what I was really enjoying. You follow a hardened warrior that joins up with what is best described as arrogant Prince Nathan Fillion and his silent mage pal after an invading force wipes out her home army. Soon afterwards, these “rewinds” start happening that make you think it’s Prince Fillion’s thoughts on what could go down depending on different actions… But then it keeps happening over, and over, and over again. Until it’s revealed that it’s basically a VR game that’s being tested and you’re left with a feeling of “f*+=ing really?” The rewinds I mentioned were basically checkpoints. Meh. 2/5 Closed Betas.
-Felipe Crespo
Daughters of the Dragon #1 – Marvel
Colleen “of the Covenant” Vincent
@CollyCol
Daughters of the Dragon #1 revives the charismatic duo of Misty Knight and Colleen Wing, first seen in Marvel Team Up #64, the Marvel superheroine partners were created by Chris Claremont and Marshall Rogers in 1977. Their 2018 iteration comes courtesy of writer Jed MacKay (Edge of Spider-Geddon) and Travel Forman (The Immortal Iron Fist). Wing remains a bad ass samurai now with the chi powers of the Iron Fist while her bestie Knight now works for the FBI.
In this issue, the two battle a decrepit assassin and Japanese puppets for the souls of youthful travelers. There are road trips, the wonders of sisterhood, warrior spirit, and heroes tripping balls. The dialogue is fun, the characters are interesting, the backdrop is funky, and the story has that 70’s Kung Fu pulp flavor without being stale. Nightwing investigations may be no more, but Misty and Colleen still are one of the best things about the Heroes for Hire corner of the Marvel Universe. 4/5 Bibles.
-Colleen Vincent
Shazam! #1 – DC
“Great Rao” Bass @kidtimebomb
I approached the first issue of this series starring He-Who-Must-Not-Be-Named-Captain-Marvel with a bit of trepidation, as I’m a bit of a traditionalist where The Big Red Cheese is concerned. I’m okay with making him a bit cartoonish, as Giffen/DeMatteis did thirty years when he was a member of their Justice League and earned that last nickname, but my tonal sweet spot is where Jeff Smith landed with his THE MONSTER SOCIETY OF EVIL mini-series eleven years back. More of a retro Darwyn-Cooke aesthetic. I was a bit shocked early on in The New 52 when Geoff Johns, famous for embracing the more heroic aspects of legacy and wonder in the DC Universe, got together with Gary Frank for a series of grim back-ups rebooting the character in which orphan Billy Batson was a streetwise, embittered, jerky little kid who seemed actually to be kind of a garbage person. I didn’t hang with that, but apparently it was all about the journey because the Billy Batson found here is more in line with his traditional plucky upbeat archetype. And it’s not like I was going to take a pass on Johns reuniting with his brilliant JSA collaborator Dale Eaglesham anyway. So, how’s the issue?
It’s a light, fun romp that does a fine job establishing the status quo, no matter your level of familiarity with the character. We meet our cast, Billy’s foster family, and the kids stop a robbery at a museum while on a field trip. Eaglesham and colorist Mike Atiyeh provide A-list sequentials throughout, always putting clear storytelling front and center but then zooming out for splashes just when the rhythm dictates, like when Billy first transforms or late in the issue when the kids make a discovery at the Rock of Eternity. That shot, in particular, does solid work emphasizing the more young-reader-friendly tone Johns seems to be aiming for, a gang of kids who just happen to have powers out in the world having adventures and solving mysteries.
Overall, an enjoyable issue. My two gripes: the first time the script references the deal with DC not being able to use the character’s original Captain Marvel name because they negotiated it away to Marvel, it landed for me and I laughed out loud at the meta-reference. But then Johns goes right back to a permutation of that same bit five pages later, which was a bit forced. Also, and this is more disappointment than gripe, I was looking forward to a THIS YEAR IN SHAZAM . . . page at the end like Johns always used to do on all of his first issues and were such effective sneak-peeks, and that did not show up. I did enjoy the solo Mary back-up, particularly the manga-style full art provided by Mayo “Sen” Naito. Hopefully, these will continue. This first issue didn’t quite punch me in the face or crackle down lightning from the sky but was a solid beginning. 3/5 Transformative Magic Words.
-Rob Bass
The Merry X-Men Special #1 – Marvel
Jimmy “Apostolic” Cupp @thejimmycupp
Marvel decided to give us 25 single page stories for Christmas, none of which connect in any way, except one. Jubilee is our main heroine for the holidays. Our writers, Chris Sims and Chad Bowers, take our heroine and her baby boy on an unplanned trip to her favorite place, the mall. This isn’t your ordinary mall, though, it’s empty except for the deadly robots and traps set for her. It’s fast paced and action packed, but super cute to watch Jubilee avoid death while trying to keep her son smiling like nothing is wrong. Besides Jubilee’s deadly mall experience, there was only one other story that really stood out because it never gets an ending. Jean Grae, our writer, has Deadpool and Jean Grey are suddenly thrust into being a couple in an unfamiliar house, with no idea how either of them got there. We find out how, but I’m hoping this is going to be a full story in a later issue to wrap it up (pun intended). With so many writes and artists, it is very hard to talk about just one. Overall, this was an enjoyable read full of very heartwarming holiday cheer. 3.5/5 Fa La Las.
-Jimmy Cupps
CategoriesComic Reviews, Featured Content, Fistful of Comics, The Sin Bin TagsBatman, Batman Who Laughs, comics, Daughters of the Dragon, dc comics, fantastic four, Image Comics, marvel comics, Self Made, shazam, X-Men
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Morsani College of Medicine Infectious Disease & International Medicine
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European Hospital
LabBook
RadBook
Laboratory/pathology
Challenges in Imaging
Rebuilding Russian radiology
Facing challenges common to any manager, Russian radiologists must also confront a funding crisis, system dysfunctions, self-referring patients, and head-hunters chasing staff.
Report: John Brosky
Sergey Morozov MD PhD MPH
‘We are not reinventing the bicycle here in Russia,’ said Sergey Morozov MD PhD MPH. Radiologists anywhere would be familiar with the experience of restructuring imaging services for the nation’s healthcare system, he added. Thanks to a recent modernisation programme, today there are new radiology systems installed in even smaller community hospitals across the country.
‘The heads of these radiology operations face the same kinds of issues confronting our colleagues across Europe or the United States. The equipment we have is the same, the standards for operating the equipment are the same, the protocols are very similar,’ stated Prof. Morozov, who is Deputy CEO at the European Medical Centre in Moscow, and a member of the Management in Radiology (MIR) Subcommittee of the European Society of Radiology (ESR). ‘As is the case elsewhere, once you receive the equipment, you need to adopt standards, train your team in working to those standards, and then begin to work in a way that is similar with colleagues elsewhere.’
The radiologist as manager
The lessons learned to this point are also very similar. ‘We have found that a good radiologist can become a manager, but it does not mean this good radiologist is going to suddenly become a good manager,’ he laughed. ‘With the expanded number of radiology systems, and a rapidly increasing demand on the utilisation of that equipment, we now understand that doctors given charge of these departments really need specific skills to run them effectively. They need to define processes and key performance indicators,’ he added.
Prof. Morozov’s work with the ESR on the MIR committee is part of a larger effort to introduce a programme for retraining Russian doctors as professional managers of healthcare services.
The next level of challenge, he said, is to build information technology (IT) systems on top of these processes to better manage hospital departments and networks of hospitals. ‘I can tell you that IT people in Russia are the same as IT people everywhere else,’ he said. ‘They often believe that they know all the answers about how to organise workflow, for example. Yet you cannot start by making IT decisions, or you will not be free in decision for managing the processes. IT comes as a systemic solution.’
Currently there is a widening gap between the level of digitisation and IT capabilities between public and private hospitals, which are moving faster to introduce PACS and hospital information systems (HIS). ‘They can make purchasing and installation more straightforward, they are more transparent in their operation, and they can assure financing because they are structured as businesses,’ said Prof. Morozov.
‘With public hospitals this all can become more complicated,’ he acknowledged. ‘It can sometimes be difficult for public hospitals to understand why they need things like PACS or IT or HIS, and to understand why they need to find the funding for these projects.’ The good news, he said, is that there is increasingly a top-down support for IT and PACS as the heads of hospital administration see an advantage in having a visibility for what is happening inside the hospital and the ability to better manage what is going on.
Radiology as a business
As with other European countries, the Russian healthcare system is under financial pressure with severe constraints for radiology, some of which would seem familiar, but much of which is peculiar to Russia. Prof. Morozov: ‘An important development is that, today, when we want to develop a new project or programme for radiology we need to prepare detailed business plans and financial analysis predicting cash flows. It is a recognition of radiology as a business, by the state hospitals as well as the private hospitals.’
Making a tough situation even more difficult, he said, is that financing has collapsed for the national programme of healthcare modernisation that equipped hospitals and clinics. ‘Unfortunately much of the equipment was often provided without service contracts, only guarantees for one year after installation. In addition, not all equipment was installed according to the proper specifications. This has left many hospitals without equipment service. Clearly the lesson has been learned that we cannot just buy a piece of equipment without thinking about service from the beginning; and on-going financing; and proper staffing and training.
‘In these areas we also have some challenges that are specific to Russia,’ he said. ‘A huge difference here is that many patients refer themselves for radiology exams. They do not come from a specialist or even a general practitioner. They go to Google Doctor and come to us saying they would like an MRI. I had one patient who, when I asked her what her health issue was, she answered she suffered T2 hyperintense lesions in the brain. Because there is not an absolute requirement that a physician must order a scan or radiological exam we have a major policy issue and we need to define patient flows to radiology’.
‘Another issue is that the percentage of patients who pay out of their own pockets for health services is rapidly expanding. Patients don’t always go to the appropriate public hospital service, but instead search for better diagnosis and treatment among private clinics. ‘Money has become the major driver of healthcare.
Radiologists as stars
Young doctors who wish to enter radiology must find a programme themselves, yet the program for training has not kept pace, so that hospitals and state universities cannot provide enough courses.
‘Today, in Russia, radiology services are perceived as a source of revenue for hospitals. Radiologists have become the stars of the healthcare system. Consequently, qualified radiologists are requesting high salaries; head-hunters are after them, making it difficult to find good radiologists and trained technicians – critically, experienced radiologists who can act as managers to run a department efficiently.
‘In addition to my hospital work, I teach at the chair of radiology at Sechenov Moscow Medical University. Five years ago we would have 10 to 15 residents each year; now we have between 50 and 60. Young doctors who wish to enter radiology must find a programme themselves, yet the program for training has not kept pace, so that hospitals and state universities cannot provide enough courses.
‘This is creating a business of post-doctoral medical education in Russia where we see private companies providing specialised training courses with experienced doctors. These private companies hire radiologists to train young radiologists. Combined with a fee-for-service model of payment, this drives costs higher and higher until we see that Russia’s healthcare spend per patient is constantly increasing. With understaffed state hospitals providing patients with poor service and a lower quality of treatment and diagnosis, those who can afford it prefer to go to a private hospital.
‘The good thing is that, over the past three years, Moscow Healthcare has acquired about 150 CT and 70 MR scanners. They are now acquiring a regional PACS system from Agfa Healthcare to connect all these scanners to create a centralised Centre of Excellence that can offer second readings for other medical centres. Here we are seeing a concerted state effort in a policy to provide better standards for radiology in imaging and interpretation.
‘The Centre for Excellence in Moscow is proving a driver for increasing quality. It creates an opportunity to enhance the education and training system. Radiologists learn a second opinion is not a punishment but a systematic review to identify discrepancies. In this way people learn how to avoid any mistakes, whether in equipment use or interpretation.’
Sergey Morozov has headed the Radiodiagnosis Service of the European Medical Centre in Moscow since 2013. An honours graduate (2002) from the Sechenov Moscow Medical Academy, he specialised in General Medicine and gained his Medical Sciences PhD for his thesis on functional MRI in 2004 and another Medical Sciences doctorate for his thesis on radiodiagnostics in orthopaedics in 2010. Dr Morozov completed multiple residencies on X-ray diagnostics in the USA (Memorial Sloan-Kettering Cancer Center), Norway (Oslo University) and Italy (La Sapienza).
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Syracuse Basketball Program Violates Drug Policy, Now Faces NCAA Investigation
The following article was written by Spencer Wingate.
Syracuse University self-reported potential violations of their drug policy several months ago, which has led to an NCAA inquiry. Yahoo! Sports reported that at least ten players starting in the 2000-01 season tested positive for banned recreational substance(s). The violations should have resulted in suspensions, but the players were allowed to play in games and participate in practices. Yahoo! cited that one player failed four drug tests but received no punishment. Syracuse stated that the violations were over the past decade, and no current student-athletes have violated drug protocol. The NCAA now must determine who was ineligible yet still participated. The time period of the drug violations include the lone national title season in 2003.
The NCAA has no uniform policy regarding drug testing or punishment. The member institutions are allowed to police themselves and determine their individual policy. When the NCAA tournament begins later this month, the organization will begin random tests through the National Center for Drug-Free Sport of every team at each game. Schools are not mandated to institute a drug policy, which leads certain schools to wait until post-season play before student-athletes are ever tested. Syracuse broke their own policy and self-reported the allegations, leading to the assumption sanctions handed down by the NCAA will be lenient. The notion is completely valid as Syracuse did violate a policy they voluntary instituted. They did not attempt to cover-up the allegations, and instead, openly came clean. In another view, they broke a policy and levied no sanctions – lacking institutional control. The bigger issue presented with the situation is the NCAA’s lack of uniformity and accountability. They have no problem enforcing restrictions with paying athletes, booster involvement, campus visits, etc. The NCAA claims these rules must be established for the betterment of student-athletes and to protect them. Why should the association not be held responsible for establishing a universal drug policy or protocol as well? It seems that would better serve the welfare of not only student-athletes, but also their universities.
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Corrine Hindson
Never knew what QR stood for. Informative article. Nice job. Guess I should use a QR code sometime.
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Go South for Winter Bass
Ask Dr. Dave: Does Culling Coyotes Work?
Ask Dr. Dave Samuel About Whitetails
Andy M. from North Carolina writes to ask about culling coyotes. “We’ve got a major coyote problem in my state and other Eastern and Southeastern states. Why do many biologists resist the idea to cull coyotes? Seems to me, getting rid of coyotes would help the deer.”
That’s a great question and one I hear from deer hunters all the time. The question is does culling coyotes change the coyote population over the long haul? Based on several studies I can say it does not. For example, a Deer Blog I receive in my e-mails, summarizes work done in South Carolina where coyotes are having a major impact on fawn recruitment. In that work, researchers removed an average of 4.2 coyotes per square mile per year from January thru April for three years. They removed 474 coyotes during that time on 37 square miles. In other words, they really hammered the coyotes. While doing that they followed 216 radio collared newborn fawns. Before coyote removal fawn survival was 23 percent. After two years of coyote removal, fawn survival was 20 percent. It did jump up to 43 percent after year three, but even so the cost to remove the coyotes was $123 per coyote and landowners or hunters just can’t afford to do that.
The Deer Blog also cited a culling study done on red foxes. That study was done on five areas in France and each area was 100 square miles in size. Hunters and trappers were recruited to help and they killed 3.8 foxes per square mile each year. That is a ton of dead critters! Carrying capacity for the foxes was estimated at 4 foxes per square mile. Even after killing 3.8 foxes per sq. mile, they could not lower late winter densities more than 25- to 32 percent and the reason was immigration. There was some impact if removal was done in the winter, but just as in the S.C. coyote removal study, it was hard to justify the expense for such a small gain.
Andy, one thing is for sure. We’ve got more coyotes than we’ve ever had, and there is a lot we do not know. But right now doing massive coyote removals just doesn’t seem economically feasible, and even if it was economically feasible, the gain in deer numbers isn’t much.
Shop Sportsman’s Guide NOW for a great selection of Hunting Gear!
If you have a question for Dr. Dave Samuel, e-mail your question to Dr. Dave in care of Tom Kacheroski, manager of Guide Outdoors. Dr. Dave studied deer for 30 years as a wildlife management professor at West Virginia University. In addition he has been a bowhunter for more than 40 years, with deer being his main prey. He’s also an outdoor writer and has been with “Bowhunter” magazine for 31 years
6 Responses to “Ask Dr. Dave: Does Culling Coyotes Work?”
Mr VJP
Why are they figuring costs for culling by researchers? Just open a year round season with no bag limit and let hunters shoot them on sight for recreation. The culling produced results favorable to deer survival. It should not be stopped because of costs that are not needed in the first place.
This is a prime example of why academia should not get invovled in the outdoors. It costs to much to do? Bullets are cheap and sportsmen are passionate about deer hunting. Killing the coyotes is the only option, if we don’t do that fawn recruitment is certainly going to go down.
Doug Derby
More coyote= more time to hunt them. Cost becomes irrelevant if it’s fun! If coyote are a problem on private property; invite a hunter in.
Michael G.
Culling does not make a difference? Well, Where I grew up there were no coyote. They had been eliminated in this area. Now they are common. Logic dictates that dead coyote do not eat deer. So it may make some difference.
This reminds me of a story about a boy who was found killing mice in the barn, The old man said to the young boy, there are so many mice out here you can’t possibly make a difference. The boy stomped another mouse running by and said, “I made a difference to that one.”
larry abel
Shop changed hands now BUT
For the past several years a local sporting goods shop
ran a largest coyote killed $1,000.00 prize per year
WE SAW VERY FEW COYOTE SIGN DURING THIS PERIOD !
and the shop had many hunters stopping BUY.
Lee Hoffman
It is your cousin. I was wondering if I could get you to sign a copy of your book and send it to
me. My phone number is 717-487-8102
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Revision as of 13:23, 29 April 2016 by Milloum (talk | contribs)
Earth > Europe > Western Europe > France > Paris
<map lat='48.83398957668602' lng='2.34283447265625' zoom='10' view='0' float='right'/> Paris is the capital of France. It is situated within a ring road called le périphérique, or le périph. The actual city is actually small but is surrounded by endless suburbs, some of them being linked to the urban public transportation system at no extra cost, and some other being labelled as outside zones and thus more expensive to reach.
Note that there is an "outer ring road" to the Paris suburb area, motorway A86 (or super-périphérique) and another wider ring called "la Francillienne" which isn't completed but still used to connect . If your ride is not going to Paris itself, you might want to clarify which ring they are going to take as it may affect the place where you'd want to be dropped.
During rush hours, it is possible (but illegal) to be quickly dropped on the ring road. This is useful if your ride is not willing to get out of it to drop you (which is often the case). Within the ring area, you are definitely linked to the whole regular fare subway system.
If you are coming from the Northeast and your ride is heading South (which is a normal truck route), chances are that your driver will not drop you on the ring road where it is complicated to stop. A frequent place to get dropped is the first exit South on the A6 called "Rungis". From there, you can reach the Metropolitan subway system with one ticket, then use one to your final destination. You can also reach other suburbs in the 94 department (Val de Marne) taking the TvM bus, which is also a normal Paris ticket.
1 Hitching in
2.1 Northeast towards Lille and Belgium
2.1.1 Porte de la Chapelle
2.1.2 Aire La Courneuve
2.1.3 Charles de Gaulle
2.1.4 Aire de Vémars Est
2.1.5 Senlis Péage
2.2 East towards Metz, Strasbourg, Luxembourg, Germany (A4)
2.2.1 Via petrol station Aire de Ferrières
2.2.2 Motorway onramp
2.2.3 From within the city limits: Quai de Bercy
2.3 Getting South or Southwest (A6, A10 or A11)
2.3.1 Porte d'Orléans
2.3.2 Porte d'Italie
2.4 South towards Lyon, Marseille, Barcelona, Italy (A6)
2.4.1 Aire de Lisses
2.4.2 Aire de Nemours
2.5 A10 South-West to Orleans, Bordeaux, Spain and A11 West to Le Mans, Nantes, Rennes and all parts of Brittany
2.5.1 Pont de Sevres
2.5.2 Massy Palaiseau
2.5.3 Péage de Saint-Arnoult
2.5.4 Chartres: a spot to go directly on the A11, after it has split from the A10
2.6 West towards Rouen, Le Havre, Caen on the A13
2.6.1 inside Paris
2.6.2 in the suburbs
3 Public transport, sleeping, and more
3.1 Going to Charles de Gaulle/Roissy airport
There are plenty of excellent spots for hitchhiking North (Aire La Courneuve), East (petrol stations and barrières de péage) and also South (Aire de Lisses). It's all about how much you are willing to pay in public transportation, and how daring you are.
Northeast towards Lille and Belgium
These are classified by cost in public transportation from Paris' centre.
This option costs one local ticket. Porte de la Chapelle is where the A1 starts. Local drivers say they often see hitchhikers there. To get there take a metro 12 to Porte de la Chapelle, then walk to the roundabout. You can try getting a ride on the roundabout (there are traffic lights, which means that cars have to stop) or you can stand on the opposite side facing the roundabout where the motorway starts. Another good option is to start hitchhiking in the same street where the metro is. There are 2 petrol stations in that very street, just 50m deeper into the city. They aren't overcrowded, and at the same time quite a few cars going up the North stop here for refill; nonetheless, at such places much is depended on your luck, and according to some hitchhikers this place won't make to the TOP10 best hitchhiking places in France. It is therefore rather recommended to hitchhike at the roundabout where a quiet lane right by the traffic lights gives you a good opportunity to get onto the motorway (avoiding at the same time all the traffic that heads for Boulevard Periphique).
-A good option to leave faster is to show on the roundabout a billboard for the airport "Charles de Gaulle". There is a petrol station before the airport where the driver could let you; don't miss it! The station is not so big and many drivers just go to the airport, but at least you can ask people whereas it could be hard and long at Porte de la Chapelle.
Aire La Courneuve
Hitchhiker Masaru at Aire La Courneuve
This option costs one local ticket or zones 1–3 ticket (eur 2.45). The petrol station Aire de Service de La Courneuve is about 2 km along the A1, north of Paris.
Take bus 150 from Porte de la Villette or bus 250 from 'Fort d'Aubervilliers (both are on metro line 7) to the stop Parc des Sports. This bus stop is next to the A1 highway. Just walk to the right from the bus stop, without ever passing under the overpass. Then walk east parallel to the motorway through the parking lot of an apartment complex. There is a wall preventing access to the motorway, but if you continue walking a few hundred meters east and up a slight grassy hill, the wall ends. You can then follow a steep, thorny path full of nettles down towards the motorway and back west towards the petrol station. There is a fence right along the motorway, but near the petrol station it has been trampled down and you can step over it.
Attention: in the winter / early spring or after the rain walking down the hill to the motorway might be difficult because of mud. In February it took 2 hitchhikers almost 40 minutes to walk down and reach the fence, after numerous attempts to keep the balance and not to fall down. It might be a good idea in this case to hitch from the entrance of the highway, right at the cross before you turn to the parking lot of the apartment complex.
From the petrol station, most drivers are only going to the airport or local communities. You should ask for a lift at least to the toll station (péage) heading north. This is a 20-minute drive down the motorway (some kilometers after the airport) and everyone has to stop here. It is a great place to get long-distance rides.
Charles de Gaulle airport can be an option for hitching North-East, although waiting times might vary a lot.
It is easy to jump the metro at terminal 2 and there wasn't anyone guarding it. Maybe the same is true for terminals 1 and 3 but I can't vouch for it.
From terminal 2 walk out of terminal and head straight to the main road. You should see signs for A1 Paris Lille. Keep following these signs until the road splits for A1 Lille. One road goes to the left, under a bridge and there are some traffic lights. The other goes to the right. Stand to the right of the right turn. Cars can stop on a dashed out area to you left or drive a little past you on the right. A couple of cars stopped right a way and I was easily able to get a lift the next service station which had lots of people driving north to Lille, Belgium and Holland. That service station was very busy and it was easy to get a lift as well as a good meal from peoples' leftovers in the restaurant including half a bottle of wine!
Aire de Vémars Est
From 'Nation' bus station (also a metro stop) take bus 351* to 'Roissypole' located at Charles de Gaulle Airport (Terminal 3). It's the last stop and payment isn't required to enter the bus.You can BLACK RIDE on this bus both ways
From the coach station there (Gare routière), you can catch the 95.01 bus to Vémars, though this bus does not run on Saturdays, Sundays and public holidays. Ask inside at the ticket office/information desk for which parking number the bus will be at (D2 in Oct 2013). The ticket costs eur 2. [BEWARE 95.01 does not work on public holidays and Sundays, so if that is the case then get down at QUEBEC because A1 ( going to Lille) highway cuts through the PARIS city multiple times and at this Petrol Station there is a higher chance of finding DUTCH Cars stopping and giving you a ride until another petrol station on the main highway, which is super busy and easy to find rides going to anywhere from Calias to Antwerp to Lille]
From the Vémars bus stop walk straight on 'Rue Pierre Curie' (D17) 400m until it merges with 'Rue de la Mairie.' Walk an additional 350m until merged with 'Rue des Vignolles' (D16).
On your left the A1 will be clearly visible, as will the 'Aire de Vémars Ouest' petrol station. From here is another 1.25km to any given entrance.
Another useful recommendation is this website, where you can virtually create any route you want to take out of the city. Coupled with Google Maps, it's an excellent tool: http://www.ratp.fr/itineraires/en/ratp/recherche-avancee
For 351 Bus Route refer to link below http://www.ratp.fr/informer/pdf/orienter/f_plan.php?loc=bus_banlieue/300&nompdf=351&fm=pdf
Note: The 351 bus service does not run on weekends, but the above link can help find an alternate route.
File:Vemars.jpg
Senlis Péage
This option costs EUR 9 (25% discount under 26) + a local ticket to Gare du Nord. The peage is 50 km North of Paris, near the town of Senlis.
Senlis has no train station, but you still buy the ticket from a train station. From Paris Nord, go to Chantilly and switch to a bus to Senlis at the "gare routière" right outside of Chantilly's train station with your ticket. Once there, you need to walk a little and you'll find a "péage" (motorway payment station - people have to stop to take a ticket). The bus driver gave me the directions. This should take around one hour.
East towards Metz, Strasbourg, Luxembourg, Germany (A4)
Via petrol station Aire de Ferrières
Quite long trip and a bit expensive. Takes you to a great petrol station, better if you speak French and good day-and-night.
The first petrol station is close to RER A station Bussy St.Georges. You can also get to this RER A station by taking bus 4 or 44 from the metro station Gutenberg.
From the RER A station walk South for about 1 km along a bigger road which will lead you to a roundabout. You can try hitchhiking from there but the needed petrol station will be just a bit more than 2 km from there. You can walk on the grass field next to the motorway - don't choose it at morning or in autumn/winter, when the grass is wet. The petrol station is called Aire de Ferrières and it's "TOTAL" company. Another option to reach this petrol station is to walk through the industrial zone of Bussy area, to the South of the railway, then reach the bridge over the motorway and follow further by walking on the grass until the actual petrol station (note that as of February 2011, there was a nice-sized fence to hop after crossing the bridge. Nothing too difficult, but a big backpack makes it harder!). Most of the walk will be on the road which means you will save some time while at the same time such a walk won't be so annoying if you happen to hitchhike in winter (then you apparently don't want to go through the fields).
Here's a map.
Motorway onramp
This one is close to Paris, faster and cheaper to get to, but still in the megapolis. Starting from there, you're likely to end up either on the petrol station described above or at the péage described above. Not good at night.
Take the RER Line A (Red) in direction of Boissy St Legere until the station Nogent Sur Marne (EUR 2.70 (2010-11). Leave the station in direction of Rue Joinville and follow the sign to the A4. It is a 30 min walk. There is a red light before the onramp. Lots of traffic, possibility to stop on the ramp for brave drivers.
Ask if your driver can take you at least to the next petrol station which is within the free motorway network. Toll gate is a bit further.
From within the city limits: Quai de Bercy
Cheap, as you will only need a metro ticket and pretty fast too.
You can also try to hitch directly from within Paris rather than taking the train for at least half an hour and then walking.
Take the metro line 14 to Bercy and exit towards Boulevard de Bercy, take the Boulevard down to the bridge where it intersects with Quai de Bercy. Standing on Quai de Bercy it is advisable to have a sign indicating you want to get onto the A4. When cars stop, ask if they are going all the way to the toll station (péage), many drivers turn off the A4 before that but there are not really any convenient places to continue hitch-hiking from before the toll station.
Getting South or Southwest (A6, A10 or A11)
These spots are close enough to the city to be getting traffic in all southern directions.
Porte d'Orléans
Once the most famous hitchhiking spot in France, this spot isn't bad nowadays, but it isn't great either. The good thing is that drivers aren't surprised to see people there, and that you don't need to get out of Paris in faraway suburbs.
Porte d'Orléans is the terminal subway station of line 4. There is an entry on the périphérique ring road where lots of people are later heading South. The best place is besides the "Novotel" building or (better) opposite it at the traffic lights. Be warned, traffic here is heavy and fast moving. If you have much baggage or more than one person I would not fancy your chances here. Waiting at the petrol station or even the adjacent war memorial will not give you the best traffic.
Make sure to specify with a sign specifying that you go to Orléans (if you are heading Southwest - A10 or A11), and that the driver will leave you at least at the "péage de Saint Arnoult". If you are heading directly South, have a sign for Lyon and make sure to be left at Aire de Lisses, roughly 35 km further, a little bit after Evry (drivers to Evry are not enough for you).
Whenever a diplomat travels between Paris and the Orly airport, he'll go through here. Which means that there will be police presence. The police don't care about you, but it is very unlikely anyone will stop while they are around. That happens often enough. They stick around for one hour.
Porte d'Italie
Similarly Porte d'Italie which is not far from Porte d'Orleans is a good place to hitch from. Additionally if you walk down the exit there at the traffic lights there is an overhead bypass which can keep you dry in the rain.
South towards Lyon, Marseille, Barcelona, Italy (A6)
Aire de Lisses
This option costs EUR 5.85 (but possible to have ride without ticket also), a zone 1–5 ticket and takes roughly 75 minutes. Aire de Lisses is the first service area on the A6, situated about 35 km South of Paris. It can save you time because you avoid all outbound traffic not really heading your direction, being after all the branch-offs.
Get the RER D towards Melun via Corbeil. Be careful to get on the right train as there are 2 routes for RER D towards Melun. As of 2010-02, the ID of the train you need was "ZIPE" or "ZOPO" (All trains on RER lines have a 4 letter ID depending on stations served). If it's too confusing (it's very confusing), get whatever train that goes to "Corbeil Essonne" and, from there, whatever train that goes to Melun. Get off at the station Villabé, the second after Corbeil-Essonnes. The station is not marked on Google Maps but don't worry, it's there: the way from Villabé RER station to Aire de Lisses
[Note, Feb 2015: There is no barrier at Villabé and so you can pay the standard central Paris tarif to get into the metro network and then just ride out there.]
A problem with a petrol station is that leaving trucks can block the leaving cars, so cars won't have chance to stop at all. Artti stood there three hours without a sign until he walked to the ramp next to the petrol station. There is more traffic and therefore more chance to get ride. Also cars have lot of space to stop.
Aire de Nemours
You can take a train to Nemours Saint Pierre (transilien R from Gare de Lyon, a ticket costs about 10 euros) and walk 45min to the service area ( http://goo.gl/VUYmh0 ). Then you're already on a paying section (no local traffic), far out from Paris (80km), and can get a ride to Châlon, Mâcon or Lyon in a few minutes.
A10 South-West to Orleans, Bordeaux, Spain and A11 West to Le Mans, Nantes, Rennes and all parts of Brittany
The A10 and A11 motorways follow the route of the A6 (see above) from Paris, and split from it near Antony/Rungis. Then, before the A10 and the A11 would split up, there is the service station of Limours-Janvry near Briis-sous-Forges and a péage near St-Arnoult, 40 km Southwest of Paris. Whichever spot you choose, ask the driver to take you at least until the Limours-Janvry service station or the péage of St-Arnoult. From these places, you can find a driver who takes you on the A10 or the A11 depending on which way you want to go.
Pont de Sevres
This option costs the price of an underground ticket. It takes you on the beginning of the N118 road which connects to the A10-A11 in about 25 km.
Take the subway 9 to Pont de Sevres, its end station. You start walking towards the bridge, where you can see the signs towards Nantes, Bordeaux, etc. The hitchhiking spot is just before the bridge, at the red lights. You can try with the cars coming from the direction of the metro station, and also with the cars which came along the river and are turning left to get to the bridge.
Hitching after the bridge in March 2015
Massy Palaiseau
This option costs EUR 4.90, a ticket for zones 1-4. This option is useful to get out of the ring roads and get directly on the A10 after all the branch-offs.
Take the RER B to Massy-Palaiseau. From there, follow the motoway signs for the A10. There are two options: take a bus from the massive transport lot beside Massy-Palaiseau station or walk down a motorway ramp nearby.
Motorway ramp option: Go down the Avenue Carnot along the Massy-Palaiseau railway, towards the autoroute. After a while there you will see a long stretch of a road with lots of space for cars. Keep going and you will reach a roundabout. If you keep following this road, you will reach a motorway exit underneath a bridge. Make sure to get a ride to the first barrière de péage (30+ km) at St-Arnoult or to the Limours-Janvry service station 5 km down the road.
Bus Option: The first petrol station named Limours-Janvry is situated near the village called Briis-sous-Forges. To get there you need to take either RER B to Massy-Palaiseau From there take the bus 91.03 to Briis-sous-Forges. It runs about 3 times an hour on weekdays, once an hour on Saturdays, and there are no buses on Sundays. The petrol station is situated a couple of km north from the village. To reach it you will need to find Route d'Invilliers, a small local road. Once you are there, make sure your driver takes the right road as the A11 starts not far away. It's not easy to find the road to the petrol station. no one in this village knows what street he is living in let alone that route you're looking for. They don't even know that there's a petrol station in the area. write the instructions and study the map!! I was lost in this village for couple of hours. Briis-sous-Forges to the petrol station map
this one (good enough one, according to some hitchhikers). Really good according to others. Took two guys ten minutes to get a ride and a third guy about the same amount of time to a different place. Lots of trucks and cars passing by!
Péage de Saint-Arnoult
You can take the RER C train to Dourdan. There are no controls on the exit, so if you are on the cheap, you need to pay only the basic metro ticket (some EUR 1.33) to get into the underground network in Paris. Once in Dourdan, cross the railroad track and turn left and then go straight on the D836 until you reach the péage after 4-5 kilometers. You should be able to hitch a car as there are many passing by and the French take easily on small routes if they see you walking. Get off just after the road crosses the autoroute, go left and in a short while, you will reach the péage. Look at the map beforehand! You have much higher chances here then anywhere else, there are lots of cars going through.
Chartres: a spot to go directly on the A11, after it has split from the A10
Hitchhiker Zoe in Paris during the 888 event
Take the train from Paris-Montparnasse to Chartres (EUR 12) and start hitching from there. You might want to go to the service station Chartres-Gasville on the A11 east of Chartres (bus plus one hour walk!). From the train station, take one of many buses that stop at the Morard station. Here starts bus 12, take it and get off at N.Conté - some minutes before you arrive there, memorize the route: the bus crosses the motorway, and comes to a big roundabout where it turns right and continues to a second small roundabout to turn right again to arrive at N.Conté. Now comes 1 hour of walk: go back to the big roundabout and turn right (east) to follow the N10 until you come to a small city. There you encounter the next roundabout, where you turn left. Follow the street, it bends to the right and ends on the Rue du Bois Paris where you turn left (north). After 500 meters comes the motorway, continue until you have crossed it. The service station is 400 meters east, so try to pass through the trees on your right and follow the street to the service station.
West towards Rouen, Le Havre, Caen on the A13
inside Paris
- Quai André Citroën, under the ring roag overpass. A lot of traffic on Friday and Saturday, as many inhabitants of the 15th and 7th arrondissements go to Normandy for the weekend. As a result, this spot is very effective on these days (20 to 30 min on average) but much worse at other times (expect to wait one and half hours).
- Porte d'Auteuil, at the last traffic light to the entrance of the A13, or even right under the "no pedestrians" sign on the shoulder to the motorway just after the light, where cars haven't picked up much speed yet and can see you well. Ask drivers to take you (at least) to Morainvilliers gas station, in Poissy.
in the suburbs
- Mantes-La-Jolie toll: take Transilien J suburban train from Saint-Lazare station. The fare is 8€ but you may not be controlled. Get off in Mantes-La-Jolie (not Mantes Station). There's a 30 minute walk to the toll gate: check the map.
- Poissy rest area (a.k.a. aire de Morainvilliers): take Transilien J or RER A from Paris and get off in Poissy. Take bus 20 to bus stop "Auberge". There's one bus every hour on weekdays, fewer than that on Saturdays and it doesn't run on Sundays. See the timetable there.
Public transport, sleeping, and more
A small collection of the "Paris" signs for the Project 888 where over 150 hitchhikers gathered and camped in front of the Eiffel Tower.
See all the information on Nomadwiki!
Public transportation of Paris
Trains and regional transports, ticket agency
Going to Charles de Gaulle/Roissy airport
Bus line 350 goes to Gare de l'Est, and line 351 - to Place de la Nation. You're supposed to validate 3 tickets (which is a lot cheaper than travelling by RER); checks are said rare to occur.
trash:Paris nomad:Paris
Retrieved from "https://hitchwiki.org/en/index.php?title=Paris&oldid=82795"
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35th Anniversary of Francis as the Patron Saint of Ecology
Care for Creation Efforts
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Home > Justice and Peace > Our Initiatives > Care for Creation > Catholic Social Teaching and Environmental Ethics > Sacramental Universe
Sacramental Universe
The whole universe is God’s dwelling. Earth, a very small, uniquely blessed corner of that universe, gifted with unique natural blessings, is humanity’s home, and humans are never so much at home as when God dwells with them.
In the beginning, the first man and woman walked with God in the cool of the day. Throughout history, people have continued to meet the Creator on mountaintops, in vast deserts, and alongside waterfalls and gently flowing springs. In storms and earthquakes, they found expressions of divine power. In the cycle of the seasons and the courses of the stars, they have discerned signs of God’s fidelity and wisdom.
We still share, though dimly, in that sense of God’s presence in nature. But as heirs and victims of the industrial revolution, students of science and the beneficiaries of technology, urban-dwellers and jet-commuters, twentieth-century Americans have also grown estranged from the natural scale and rhythms of life on earth.
For many people, the environmental movement has reawakened appreciation of the truth that, through the created gifts of nature, men and women encounter their Creator. The Christian vision of a sacramental universe–a world that discloses the Creator’s presence by visible and tangible signs–can contribute to making the earth a home for the human family once again. Pope John Paul II called for Christians to respect and protect the environment, so that through nature people can “contemplate the mystery of the greatness and love of God.”
Reverence for the Creator present and active in nature, moreover, may serve as ground for environmental responsibility. For the very plants and animals, mountains and oceans, which in their loveliness and sublimity lift our minds to God, by their fragility and perishing likewise cry out, “We have not made ourselves.” God brings them into being and sustains them in existence. It is to the Creator of the universe, then, that we are accountable for what we do or fail to do to preserve and care for the earth and all its creatures. For “[t]he Lords are the earth and its fullness; the world and those who dwell in it” (Ps 24:1). Dwelling in the presence of God, we being to experience ourselves as part of creation, as stewards within it, not separate from it. As faithful stewards, fullness of life comes from living responsibly within God’s creation.
Stewardship implies that we must both care for creation according to standards that are not of our own making and at the same time be resourceful in finding ways to make the earth flourish. It is a difficult balance, requiring both a sense of limits and a spirit of experimentation. Even as we rejoice in earth’s goodness and in the beauty of nature, stewardship places the responsibility for the well-being of all God’s creatures.
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Samsung announce Smart TVs will soon have AirPlay 2 and iTunes support
By Homes| 1 year ago
In an industry first, Samsung Electronics announced today it will offer iTunes Movies and TV Shows as well as Apple AirPlay 2 support on 2019 Samsung Smart TV models from the first half of this year.
It's finally happening: major tech companies are realising allowing cross-system compatibility will help their bottom line and keep consumers happy.
Customers don't want to be forced into choosing one system for every tech device in their lives, but it seemed the overarching philosophy of companies was to do exactly that, as we furiously Googled ways to stream from one device to its competitor -- until now.
Samsung is thankfully leading the charge, allowing iTunes and Airplay 2 compatibility on their 2019 Smart TVs, effectively bridging the divide between two of the biggest tech companies on the planet.
If you own a 2018 Smart TV, don't worry -- support will be made available via firmware update.
It's finally happening. (Samsung)
A new iTunes Movies and TV Shows app will debut only on Samsung Smart TVs in more than 100 countries. AirPlay 2 support will be available on Samsung Smart TVs in 190 countries worldwide.
Samsung customers can access their existing iTunes library and browse the iTunes Store to buy or rent from a selection of hundreds of thousands of movies and TV episodes — including the largest selection of 4K HDR movies.
iTunes Movies and TV Shows will work seamlessly with Samsung’s Smart TV Services, such as Universal Guide, the New Bixby and Search, to create a consistent experience across Samsung’s platform.
But what we're most excited about is the AirPlay 2 compatibility.
Mums are rushing to buy this $5 denture cleaner
Jamie Oliver is moving his family into a 'haunted' 16th century mansion
The $58 hack that turns a regular TV into a smart streaming device
With AirPlay 2 support, Samsung customers will be able to effortlessly play videos, photos, music, podcasts and more from Apple devices directly to Samsung Smart TVs, including QLED 4K and 8K TVs, The Frame and Serif lifestyle TVs, as well as other Samsung UHD and HD models.
“We pride ourselves on working with top industry leaders to deliver the widest range of content services to our Smart TV platform,” said Won-Jin Lee, Executive Vice President, Visual Display Business at Samsung Electronics.
“Bringing more content, value and open platform functionality to Samsung TV owners and Apple customers through iTunes and AirPlay is ideal for everyone.”
Auto news: BMW 1 Series scores five stars in ANCAP testing - caradvice.com.au
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You are here: Home / Uncategorized / Croatia: With Kolinda Grabar-Kitarovic “Berlin Wall” To Finally Tumble Down
Croatia: With Kolinda Grabar-Kitarovic “Berlin Wall” To Finally Tumble Down
January 4, 2015 by inavukic 55 Comments
Kolinda Grabar-Kitarovic
Candidate for President of Croatia
In one week, on January 11, Croatian presidential candidates Ivo Josipovic and Kolinda Grabar-Kitarovic face their final battle for the Office of the President. One of the more significant platforms pursued by Grabar-Kitarovic in her election campaign is “the return to where Franjo Tudjman stopped”.
“He (Tudjman) is a man who gathered us all around the idea of freedom and independent Croatia and, led by him, the Croatian people and all the citizens who fought for Croatia, our state was created and it’s now our duty to complete the work he started and take Croatia into prosperity,” she said in December 2014 at the 15th anniversary of Tudjman’s death.
When Croatia seceded from Yugoslavia in 1991 the communist Yugoslav Secret Police (KOS, UDBA) controlled a great deal and Croatia was faced with a brutal war of Serb/Yugoslav People’s Army aggression. This was the time just after the “Berlin Wall” came down, promising freedom and democracy to Eastern European countries that had been suffocated by Soviet-led or Soviet associated communist regime for decades, since WWII.
Franjo Tudjman, announcing paths to freedom from the Yugoslav communist regime and democracy for Croatia started the tearing down of the “Berlin Wall” that had existed within former Yugoslavia since WWII. In the early 1990s Croatians, led by Tudjman, along with Slovenians and eventually Bosnia and Herzegovina and Macedonia, turned towards West (while Serbia and Montenegro, along with those organised individuals in the other aforementioned Yugoslav states wanted communism to flourish, dug their vicious pro-communist heels in) and broke their ties with Yugoslavia, which was dominated by the Serbs. Most, but not all, from the Serbian minority in Croatia tried, with the help of the Yugoslav Army, to stop Croatia’s secession from Yugoslavia. After several years of bloody armed struggle, Croatians managed to militarily defeat the Yugoslav Army and the Serbian rebel forces.
But this success of Croatian Homeland War veterans and their leadership was not to see uninterrupted the next phase that would entail putting into place all the necessary political, ideological, administrative and legislative actions within Croatia that would see Tudjman’s path for a truly democratic and prosperous Croatia in action. The viciously ardent communists, led by Stjepan Mesic, staged and aided an all-out war of vilification against Tudjman and Croatian Homeland War Generals, setting their sights on criminalising the war and equating the victim with the aggressor. As the new Croatian state was formed during the Homeland War, the former Yugoslav communist Secret Police was not dissolved, allegedly because the new Croatian leadership could not risk an ‘internal war’ with the remains of the totalitarian regime. At the time Tudjman was to support lustration – removing from higher office those who were operatives of the Yugoslav Secret Police – the chase to vilify him as an ultra-nationalist who participated in joint criminal enterprise against Serbs in Croatia picked up and constantly threw dust into the eyes of those who wanted to work on further and more profound democratic changes in Croatia. (It took 18 years for the International Criminal Tribunal of Former Yugoslavia to peel off this vilifying coat when in 2012 Croatian Generals Ante Gotovina and Mladen Markac were acquitted of crimes they were charge with as Generals of Tudjman’s army…)
By the year 2000 “reformed“ communists came to power in Croatia, both in Government led by Ivica Racan and in Presidency of Stjepan Mesic. Ivica Racan’s former Communist Party changed its name to “Social Democratic Party,” yet everything else remained the same. They kept their close relationships with the Serbian minority in Croatia and the Serbs in former Yugoslavia – with the same old communists in their respective positions of leadership. Stjepan Mesic, having been ousted as parliamentary speaker in 1994 by Tudjman on account of his vicious and vilifying attempts to oust Tudjman from power, had meandered through creating new political parties to acting as independent to stay in power and continue his work on burying the democracy Tudjman had set as Croatia’s goal.
Social Democrats and Mesic had pushed on with “drowning” Tudjman and Croatia’s Homeland War and resurrecting communist Yugoslavia’s Josip Broz Tito along with suffocating the efforts to bring communist crimes perpetrated during the times of communist Yugoslavia to justice. Croatia’s current president Ivo Josipovic had picked up where his predecessor Mesic stopped and Prime Minister Zoran Milanovic where Racan’s government had stopped. Croatia had become a battleground where values of communist Yugoslavia were elevated above those of Tudjman, Homeland War and democracy and, hence, widespread corruption that has its roots in communist Yugoslavia continued to flourish no matter which political party was in government after year 2000.
“Instead of reforming the economy and cutting the government costs, Croatia continues to borrow and sell off national treasures, while increasing taxes. As of today Croatia is the EU member with the GST/VAT at 25%, and with the highest unemployment rate, especially among young professionals who increasingly seek relief from poverty and existential hopelessness abroad.
The Croatian media scene is dominated by the same people who used to glorify former dictator Tito. The current head of the national television, the “HRT,” is Goran Radman, himself the last president of Tito’s communist youth organization. This well-rehearsed team sends to jail or fires someone every week because of “corruption,” in order to distract people’s attention from the real problems. The vast majority of cases involve political opposition leaders.
The media is served a steady stream of “secret” witness depositions, demonstrating how the country is being robbed. At the same time the attention is drawn away from the real problems, concealing the fact that the fleecing of the country is carried out by the government itself.
Increased taxes, no investments, no encouragement for private investment projects, halting the funds earmarked by the EU – all this seems to be the hallmark of the Josipovic’ regime” writes Dan Rados of The Daily Caller in his thought-provoking article titled “Is Serbia controlling Croatia by blackmailing its president”.
All that and much more seems the hallmark of the politics of those who do not want a democratic and prosperous Croatia and they are those who remain loyal to the values of communist former-Yugoslavia. One wonders how much of this pro-communist Yugoslavia outlook has stopped Ivo Josipovic visiting again the protest-camp site outside Veterans’ Affairs ministry building in Zagreb where 100% war-invalids have been rallying for changes and rights since October 2014! I.e., aloof faced, Josipovic has visited the protesting veterans on 24 October and has done not a thing then or since then in attempting to truly listen to the suffering veterans, to create or help create a constructive dialogue and seems unperturbed by and deaf at the veterans’ plights. His excuse for failing to speak to the protesting veterans since late October is that he has invited them to visit him in his office! And this is the man who tries to tell the people that he too holds that independent Croatia of today is based on the values of Croatia’s Homeland War (as well as antifascist)! The communists of today, such as Josipovic, seem brazenly and spitefully determined not to let Croatian Homeland War veterans achieve fully an upper hand they deserve.
Throughout the campaigning for the presidency of Croatia it has been so refreshing to come across a candidate like Kolinda Grabar-Kitarovic who, unlike Josipovic, emanates with democratic justice, providing for citizens’ and human rights for everyone based on the law of the country, due process and fairness. She is adamant in unifying the Croatian nation into working towards the goals set by Tudjman and, unlike Josipovic and the Social Democrat led government, appears to place Homeland War veterans above any former communist or antifascist crusader. With her victory on Sunday 11 January Croatia is surely to start breathing fairness and justice once again and the “Berlin Wall” will finally tumble down for Croatia just as it has many years ago for the other European countries adversely affected in the past by it. Ina Vukic, Prof. (Zgb); B.A., M.A.Ps. (Syd)
Filed Under: Uncategorized Tagged With: Berlin Wall, Communism, Communist Yugoslavia, Croatia, Croatian Homeland War, Croatian presidential elections 2014, Franjo Tudjman, Ivo Josipovic, Josip Broz Tito, Kolinda Grabar-Kitarovic, Stjepan Mesic, transitioning from communism, UDBA
« Croatian Presidential Elections Set Dead-Heat Conditions For January Run-off
Croatia: Known High Love Or Alleged High Treason In Next President? »
HRVAT iz Like says:
Please Help Save Croatia !!!
Spread the truth and help keep Croatia safe from those who seek to extinguish her freedom.
TRUTH will always set us free and give hope to the preservation of LIBERTY.
>>>http://youtu.be/GwUiFJi4U2s
>>>http://youtu.be/XR0wnSJm4Vk
inavukic says:
Thank you Hrvat iz Like – all who I know are doing just that – voting for Kolinda
President Josipovic’s Bloody Totalitarian Pedigree which was hidden from the majority of the Croatian electorate both at home and in the diaspora as well as the world’s mainstream media until recently exposed:
http://narod.hr/hrvatska/boze-vukusic-josipoviceva-oca-povezuje-se-s-likvidacijama-hrvatskih-politickih-emigranata-diljem-europe/
There are things coming out about Josipovic’s father’s role in the communist regime,Hrvat iz Like, including Goli Otok/Island where innocent people who were against communism were tortured, died etc – and while Josipovic is not his father Josipovic, and while one should not believe as true everything that is written without proof, Josipovic is guilty of obstructing justice and doing everything in his power to stop prosecutions of communist crimes.
I pray she and her Light win through.. xxx
Me too, sue – thank you
An I forgot to add Ina.. Happy New Year to you… 🙂 May it be filled with abundance of Health and Happiness.. x
Happy and a wonderful New Year, Sue
therealamericro says:
Ina, please forward Ms. Grabar-Kitarovic and HDZ these questions for clarification before election day, I believe I speak for more than a few Croats after watching the debate against current President Josipovic.
1. In terms of Presidential decorations to individuals and organizations, why did she not mention Josipovic’s praise for, and authoring of the charter of, Documenta, an organization that worked closely with Savo Strbac (http://www.hic.hr/english/index_Strbac.htm) and his sham Milosevic-initiated NGO “Veritas” – who recently stated that “It is lawful to kill civilians in war” (http://www.sense-agency.com/icty/shepherds-exchanged-for-prisoners-sheep-buried-in-ovcara.29.html?cat_id=1&news_id=16209)?
2. What, at all, can be considered positive about Stipe Mesic’s Presidency which skyrocketed the budget of the Office of the President, with the obscene expenditures for personal interest including a lavish Mongolia vacation at the expense of taxpayers, not to mention the slashing of the budget for funerals for veterans, getting rid of the reserve forces as well as mandatory draft, and the office of the presidency and bureaucracies under it’s control, actively operating against Croatia’s national interests, namely media agitprop against Gotovina and the Homeland War? Would a Grabar-Kitarovic presidency push for the a) Investigation into Mesic’s monstrous and false claims – debunked by the initial UN study into Bljesak – to the US Embassy regarding both Operations Bljesak and Storm, as well as the non-chalant throwing around of Top Secret documents, and opening the Tudman Presidency archives to foreign journalists, many of whom were known to Croatian intelligence agencies to be spies? Will Mesic’s perjury at the ICTY against Blaskic, Kordic, and the HVO, be investigated, in addition to Manolic’s perjury against the aforementioned?
3. Will Kolinda Grabar-Kitarovic push for, as President, legislation that would free Croatians from abroad and returnees from being double income taxed – with the nation of their pension or pay origin being the only tax they have to pay – so as not to waste time signing dual-taxation agreements (which are entire bureaucratic processes) to make Croatian political and economic emigre returns and retirements move smoothly and potentially be immediate for those who have the resources and desire?
4. Is the Visegrad Group a top political-economic-military priority, and will it be the number one agenda item in addition to closing all open questions with Serbia and RS in regards to missing persons, war damages, etc.?
5. Will being a member of both the German and V4 battlegroups be both strategic and tactical top priorities?
6. Does she support the creation of a Croatian Entity in B&H, or at least a confederalization of the Federation following the Swiss model – or at least at a minimum, respecting the pre-2000 Dayton agreement on-the-ground reality that existed?
7. If Serbia does not meet all Croatian requests for information and action regarding the war, will she as president do everything possible to prevent their entry into the EU?
8. Will Croatia with Grabar-Kitarovic as President, allow US, UK and Five Eyes intelligence services to violate Croatians’ privacy at a 100 percent rate (https://firstlook.org/theintercept/2014/12/04/nsa-auroragold-hack-cellphones/), as they have since 2012 with very unfriendly and invasive Auroragold spyware program?
9. Will a Grabar-Kitarovic Presidency see the US, UK and Five Eyes sat down and told they hand over all information gathered on innocent Croatian citizens to Croatian authorities and destroy their copies, otherwise face an Embassy recall?
10. Will a Grabar-Kitarovic Presidency consider the creation of an autonomous internet platform, something that can be replicated and exported for profit, with proper encryption procedures to protect citizens identities and freedom of speech, to lessen the invasive and criminal, out of control Five Eyes Orwellian surveillance practices which is nothing short of creating a file on every citizen and their social network for social control and future blackmail?
11. Will a Grabar-Kitarovic Presidency see a very public stance, and demand signed agreements for non-spying by EU and NATO allies on Croatia, and visa versa, nor spying on Croatian citizens outside of permission from both Croatian parliament and the respective national security committees and intelligence and law enforcement bureaucracies, limited solely to organized crime and *actual* (not thought crime) terrorist threats – namely human trafficking, hard drug transportation, and *credible* terrorist threats, specifically Islamist militancy, Croatia’s only real threat outside of renewed Serbian aggression which for now seems unlikely.
12. Under a Grabar-Kitarovic Presidency, will Croatian intelligence services begin to investigate and prosecute paid and unpaid foreign government’s local agents of influence, such as those Croatian citizens who work at the State Department online English language strategic propaganda front Balkan Insight (www.balkaninsight.com) – including Drago Zvonimir Carlos Pilsel who was Josipovic’s first choice for Press Secretary – which until March 2012 was run by a middle aged Serbian American management employee of the State Department, almost certainly a Media Information Operations Officer, from Chicago, who was replaced by a younger Serbian American State Department employee from Chicago that same month?
13. Will a Kolinda Presidency see a full and thorough Croatian Parliamentary investigation into, and push for an EU investigation into the Hercegovacka Bank armed assault and literal OHR running into the ground under the control of Toby Robinson, which was nothing short than an attack on economic freedom of Croats in B&H, who have frozen accounts and or have to pay up to 50 percent of their accounts to withdraw the balance?
14. Will the return of the draft and a military reserve forces follow the Swiss or Nordic model, and will ranks at the time of discharge from other NATO military’s be recognized for Croatian citizens who were born, lived or served outside of Croatia be potentially held for those Croats from abroad that would like to serve in Croatia’s reserve forces?
15. Will a Grabar-Kitarovic Presidency see the total transparency of ALL non-governmental institutions’ finances with no exceptions, to and include generously SDP government subsidized Documenta?
16. Will a Grabar-Kitarovic Presidency see an independent study on to the war on drugs on a cost-and-effect basis, and would the decriminalization of hemp, marijuana and hashish, as well as special tax for them (to finance health prevention programs, including heavy drug use, intravenous drugs, etc.), be an item of consideration?
17. Would a Grabar-Kitarovic Presidency consider a push for non-GMO agronomy for Croatian farmers and farming companies, and, along with industry, see a zero corporate tax for five years with a to be determined incremented increase in tax for corporations or individuals that invest into both green, natural agronomy and the industrial sector? Will her presidency resist the Monstanto and similar lobbies dictats, usually backed by strong Western governments, and prevent the destruction of one of Croatia’s many strategic resources, its soil?
18. Will a Grabar-Kitarovic Presidency see the closing of the office of the former President Mesic, and will she prevent such for Josipovic if she wins, and for herself upon serving her term?
19. Will a Grabar-Kitarovic Presidency see a focus on strengthening Croatia’s gold reserves and ensuring Croatia’s currency is gold and not a fiat currency-based?
20. Will Kolinda Grabar-Kitarovic publicly call out President Josipovic for his hiring of national security threat Dejan Jovic, a pseudo-academic who made his career engaging in an endless apologia for Tito’s Yugoslavia and greater Serbian aggression, whose work at and for the Royal Institute of Economic Affairs, a known MI6 media front was removed from the web conveniently prior to his hire, to the most important security position in the office of the presidency?
21. Would a Grabar-Kitarovic Presidency consider to be the start of a graduated decrease in taxes with a flat tax of 15 percent for both individuals and corporations an end goal?
22. Will a Grabar-Kitarovic Presidency push for legislation, such as two years’ without taxes, to stimulate permanent, or partial out-of-the-year, Diaspora returns, especially in formerly occupied and post-war areas?
23. Will Croatia’s military under a Grabar-Kitarovic Presidency be spared from certain powers’ foreign policy neo-imperialist blunder-adventures, such as the lie-based Iraq war, or a military intervention into Syria which would only boost the power of ISIS?
24. Will a Grabar-Kitarovic Presidency lobby at all levels for the findings of Lt. Col. Dr. Charles Schrader and his seminal work, “The Muslim-Croat Civil War in Central Bosnia, 1992-1994,” to be submitted into evidence and Lt. Col. Dr. Schrader be a witness as it seems it was politics, not law, that prevented both his work and him from appearing at the Plic et. al. trial?
Thank you, therealamericro – the questions will be forwarded indeed.
Sunman says:
therealamerico for President!! Seriously.
Thanks bro, but I’d say Kolinda is a better diplomat than I so I think she is a much better choice.
Brankec says:
Therealamericro – quit showing off! 😉
; – )
I meant to say Drago Zvonimir Carlos Pilsel – though Hedl as well writes for the State Department’s strategic propaganda site, along with the entirely discredited Boris Pavelic, and the very whiny Josip Ivanovic and teary eyed Sven Mikelic.
BI is engaged in false advertising and client and reader deception, part of a larger agitprop program that is self-evident, but well hidden.
Name change noted in original comment, therealamericro, thanks
Mrs. Grabar-Kitarovic, my apologies to her.
Ina, I just want to wish you a belated happy New Year. Again, thank you for your continued dedication towards Croatia. How I wish a light would finally shine on our long-suffering country & Croats worldwide.
I have a request, from yourself or anyone from this blog willing to take it on – could you translate the article by Dan Rados to Croatian? I would attempt it myself, but I don’t think I could accurately convey everything and it is a very important article to read. Lots of hateful opposition to the article is already seen (because truth hurts), but funnily enough, hardly any strong, factual argument presented against the points brought up, only accusations of Croatian racism and the very unique no-one-ever-thought-of-it-before Ustasha insult.
Kat, Happy New Year too – re Dan Rados article I notice it has travelled the world many times over, picked up by many media outlets etc – re translation – if time permits I will try indeed. Cheers
Kat the replies are hilarious. Any objective reader can see that Rados hit the nail on the head – hence the fallaciously “reasoned” venom.
This sensitive topic is something the Croatian media are not touching on of course, outside of small outlets.
This would be a great rhetorical question for Grabar-Kitarovic to repeat up to the elections, along with how it was possible that Dejan Jovic was ever considered, let alone almost served Josipovic’s entire term, as his Chief Analyst, in addition to paid State Department propagandist Drago Zvonimir Carlos Pilsel, who was writing for Serbian American State Department managed strategic propaganda front engaged in false advertising, Balkan Insight, at the time of Josipovic’s offer, the first choice for his Press Secretary.
The truth hurts and the truth dismantles the Yugotopia reality right before the eyes of its cultists. That is why any brutally honest questioning of Croatia’s current reality is met with such hostility, and frantic anti-Croatia spin, but with little factually based arguments to disprove the writings of people such as Rados.
Of course the Croatian media doesn’t speak – why would they turn on themselves when they can enjoy their ill-gotten power?
There are certainly many questions I would love to see Grabar-Kitarovic answer with the most honest, brutal of truths (questions you post much better than I could), but in the political climate we find ourselves in today, it will take a more diplomatic approach. Starting to dismantle the leftover Yugoslav power structures which hold Croatia hostage will come with resistance, hostility and venom; it’s a process that will take a strong will, a Croatia-first mindset and absolute lustration.
Even just thinking about what it’ll take to improve Croatia leaves me feeling overwhelmed. I dread to think about what another five years of Josipovic will do. Political struggle is nothing new for Croatia, but it would be delightful to see some positivity.
Check out Pages 12 to 13 Boka CroPress translation of Dan Rados article already published plus analysis & comments added after sub-title “Predsjednikov reizbor”
https://inavukic.files.wordpress.com/2015/01/boka070115_no116_web.pdf
Could a paid placement of the translated article in a leading Croatian daily have an impact on the elections; any strong and well documented article that serves to better Croatia during the elections is a good thing. Count me in for a donation to help pay for the placement.
I hope the people return Kolinda Grabar-Kitarovic with a huge majority as a sign they want a real Democracy to start in their homeland. I hope she then goes on to show other Countries in the West what a true Democratic country can be like.
Hear, hear – David. She certainly seems to have the know-how and stamina for what you’re referring to. Cheers
Great post and shared here: http://wp.me/p4NkMr-7g
You really are so welcome you write such great posts and l have learned so much personally about Croatia. So we both gain by me reposting you brilliant articles. 🙂 Ian
Thank you, Ian and cheers
Ace News Room now embedded in sidebar of this blog with link, Best regards and thank you!
I feel honoured and thank you.
jmsabbagh says:
Outstanding post.Tudjman laid the foundation for greater future for Croatia,hope 2015 will unite the country to achieve the message.Warm regards.
Thank you Jalal and cheers
Heartafire says:
Happy New Year! Wonderful text as always. I am at a new address Ina, https://aheartafire.wordpress.com/.
Thank you, Hollie – Happy New Year!
I think a good start for exposing the infowar / psyop against Croatia that SDP did and still supports, with the endless financing and complicity of the Anglo-American propaganda empire, who framed Lustration as “discrimination” in the 90s and since, would be to submit FOIA requests on all government and nor known government NGO front financing to Balkan Insight – who, while demanding transparency are untransparent about their financing sources – as well as any US government personnel being employed there, and their names and job positions.
Maybe that would be something Mr. Kuzmanovic and or Mr. Misetic would be interested in. RFERL, SETimes (wholly a EUCOM project) and above all, Balkan Insight, are part of a parallel reality projection and perception management campaign. As well as surveillance (of commentators).
Yep 🙂
I would also add that FOIA requests on the total number of those – specifically Five Eyes member states citizens’ – surveilled or investigated for commenting on RFERL, SETimes or Balkan Insight, as well as their identities, and ethnic origin, might be quite useful in exposing certain illegalities of the IC, specifically DARPA, Dept. of State, and other out of control Orwellian government bureaucracies.
Indeed, very worth pursuing, therealamericro
When one looks at the financial backers of Balkan Dimsight, I mean Insight, some very interesting organizations and names come up.
Very interesting groups (http://www.blacklistednews.com/CIA%E2%80%99s_Hidden_Hand_in_%E2%80%98Democracy%E2%80%99_Groups/40721/0/38/38/Y/M.html).
Interesting read, indeed, therealamericro – the twisted part of “public democracy” sweeps doesn’t occur all of its own bat indeed…
Ina, Happy New Year. Zivjela.
Did you see this article re. the recent election results and those coming from Bosnia-Herzegovina ?
http://glasbrotnja.net/kolumne/kolumne-tihomir-dujmovic/tihomir-dujmovic-kakva-prevara-milanovic-josipovic-ukrali-sto-tisuca-glasova-kolindi-grabar-kitarovic
Thank you Erica, I did see it briefly but didn’t read it all which means yet to read 🙂
Hi Ina, I am an Australian citizen living in Sydney. I do also have Croatian citizenship…. am I able to vote on these elections from Australia?
Unless you had pre-registered by 17 December you cannot vote this time, Ivan. The buggers have changed the system this time undoubtedly to reduce the number of voters against Josipovic, so they introduced pre-registration for all voters in diaspora while in previous elections one who had no registration of abode in Croatia could simply turn up on election day, not this time. So yes you are eligible to vote but if you did not register by 17 Dec you cannot this time.
Connor Vlakancic, HR/SAD U.S.President candidate, Nov.2016 says:
Dober dan, Lijepi pozdravi iz SAD.
Review http://www.bbc.com/news/world-30614291
This 11 January runoff election follows the 28 December 2014 election. That Croatians must vote in government elections during the Christmas / New Years holiday is a travesty legacy of communist era anti Christian propaganda. All Yugoslav era laws are communist laws and now finally naša domovino Croatians and Croatian diaspora must elect, NOW, democracy government leadership to challenge these Yugoslav era communist laws!
I lived in Croatia most of 2009-12 and I personally know both 11 Sijecznj President candidates and have carefully considered that, in 2015, five years since previous election, Croatia is a significantly different nation. Thus, I have concluded that Kolinda’s election is now critically appropriate to advance international awareness and interest in Croatia as a best choice destination for tourist travel, business investment and political support.
I am currently preparing a 2015-16 Croatia promotion project so heartfelt that it will mobilize all US Croatian diaspora (and worldwide) also with HR national media boosting enthusiasm & proactive events. It will enhance US recognition of Croatia as a world-class destination with attaining new demand for Croatian export products (also halved HR VAT taxes). Also, by 2017, to achieve Croatia is included in the USA Visa Waiver Program (VWP)! I invite your interest with follow my progress.
http://www.croatia.org/crown/articles/4721/1/E-A-Search-For-Roots—Stivan-Cres-Croatia.html
http://hr.connorvlakancic.com/iz-medija
For other info: Google search my name.
And twitter.com/connorvlakancic
Also FYI, my company imports Osječko pivo to USA.
Sve najbolje tebi i tvojima,
Connor Vlakancic – Coalitions Director
cv@connorvlakancic.com
Thank you on the comment, Connor! Totally agree, Kolinda is placed best for the reasons you say and much more! Cheers and let’s vote in or support change and progress for Croatia 😀
Just put this post on and add link back to your post here: It is here: http://acenewsservices.com/2015/01/12/belgrade-kolinda-grabar-kitarovic-wins-croatian-election-with-landslide-victory/
Thank you Ace New Group – as always, much appreciated
Welcome as always 🙂 Ian
Edo Palace Mix
Takae, so simple, fluttering on the wind of vegetarian
existence, refusing to eat up more than her share,
presenting herself a second time, but finding no taker,
is less than joyous, yet remains so gentle. Two swans
glide, bobbing for minnows, mated for life, fed by ample
moat, seen by hundreds each day. Mostly Takae yearns
to be the swan on the right, head held up, pet of the palace.
Instead, like the sour gooseberry picker, Chekhov’s Nikolay,
she labors at city hall. Better, like the clerk job Kafka had, or
Poe’s daily grind, Takae, so full of wonder, but now resentment
too, as youth slips into middle age with no permanent necker,
glider, lover to snuggle with. Yellow petunias with purple eyes
stretch open to us, and I think that Takae will see this exact
pattern and find comfort having spent a day in Chiba
with friends that will, over time, form a second base.
A dream fulfilled erases previous disappointment. How to
meld dreams into the closeness that supports? Elephant ear
plants glisten under gray. Bamboo rustles, imperial reminder
that one generation can be the foundation of new style, culture,
love, beauty, art, strength, ethics, for centuries to come.
Croatia: ‘ With Kolinda Grabar-Kitarovic “Berlin Wall” To Finally Tumble Down ‘ | Ace News Room says:
[…] Published on January 04 2015 […]
Leave a Reply to inavukic Cancel reply
Role of Croatian Diaspora – Ina Vukic on Laudato TV July 2019 – Click Image to link to Youtube video
Croatia and Blessed Alojzije Stepinac (video in English)
Pope John Paul II declares Alojzije Stepinac Blessed
LOOK IN ARCHIVE HERE
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DAILY WORLD NEWS @ ACE
The Good conquered in the end: Croatian Generals acquitted
Roy Gutman on massive systematic war crimes by Serbs in Croatia – October 1991
Croatia: History & People I
Croatia: History & People II
What advice would Nelson Mandela give to Julienne Busic?
Croatian Language Project Elevated To Cultural Heritage Status
Croatia: In The Quandary Of Voting For A “Lesser of Two Evils”
A Blessed and Joyous Christmas
For Baka’s Homeland: Eyewitness To The Birth Of A State By Michael Palaich
Croatia: Winning Votes Requires A “Cluster-Bomb” Approach
Croatia: Championing Small Business With Western Knowhow – Interview With Eugene Brcic Jones
Croatia: In The Throes Of Threat Of Illiberal Democracy
Croatia: Interview With Hrvoje Zekanovic
Croatia’s Government Turning A Deaf Ear To Concerns From Diaspora
Click Picture for Timeline: Croatia 1900 - 2012
Welcome to my blog. Here I will bring to you a variety of topics covering the documented truth about that terrible war that Croatia had to endure during the period between 1991 and 1995 and about Croatian political history that shaped a wonderful nation of people.
Croatian people wanted independence for centuries, just as they had it until the twelfth century but fate was not on their side – others wanted their beautiful land. In late 1980′s the will to break free from Yugoslavia which suffocated freedom and self determination through harsh communist party rule finally bore the desired fruit.
In June 1991 Croatia declared its independence; soon after the aggressive war against Croatia broke out. The struggle of the Croatian people for self-determination was a just one. But I fear genuine justice has not been served as there have been, and there still exist, international covert and overt moves to equate victims with aggressors continue in attempts to change history. Truth often becomes obscured and lost and that is why I have chosen to write this blog, to concentrate on actual events and issues about Croatia – wishing it a bright and freedom-loving future.
It certainly was not easy to come out of the war that was fought on two fronts:
1. On the military front the world’s public has seen the indiscriminate bombardment of Croatian cities, towns and villages from land, sea and air; the destruction of civilian targets including homes, schools, hospitals, churches, factories and cultural monuments; the blockading and destruction of roads, bridges and ports; the blockading of power, water, food and medical supplies. What hasn’t been shown on our television sets is the forced clearing and evacuation of towns and villages, followed by looting, torture, rape and murder carried out by the Serbian forces, who were initially backed by the federal Yugoslav army that was largely constituted by Serb nationals; the transportation of multiple hundreds of innocent Croatian civilians from Croatia into concentration camps Serbia (Begejci, Stajicevo, Sremska Mitrovica... from October 1991, and later (1992) transferred into Serb-held camps in Bosnia and Herzegovina (Omarska, Keratern, Manjaca, Trnopolje).
2. The second front was the war of political propaganda centred on: misinformation about the rights of minorities in Croatia; portrayal of the Croatian people as Ustasha or Fascists; the representation of the Croatian defence forces as illegal paramilitary units; the representation of the Croatian and Slovenian republics as unreasonable secessionists who are unwilling to negotiate; a regurgitation of distorted facts about World War II.
Indeed Croatia had an absolute right to defend itself and this is often forgotten if not often denied it.
Ina Vukic
Ina has been a tireless volunteer on humanitarian aid and fundraising for victims of war in Croatia, Bosnia and Herzegovina, especially war orphans. From1991 to beginning of 1994 she contributed in lobbying for international recognition of Croatian independence and Croatia’s rights in defending its territory and people from military aggression by Serbian forces. For this dedicated voluntary work Ina was awarded two Medals of Honour by the first president of the Republic of Croatia in 1995 (Commemorative Medal of the Homeland War and Order of the Croatian Trefoil).Ina has also written hundreds articles for newspapers in Australia and Croatia on the plight of Croatian people for freedom and self-determination, developing democracy in former communist countries. She holds two graduate and one post-graduate university degrees, specialising in behaviour, clinical and political psychology and management.
@SWolf1947 He is deranged and, hence, dangerousGet this 1 day ago
@FranjoJuri5 https://t.co/mgUDhgR38dGet this 2 days ago
@recina790 https://t.co/eXX3bgavfnGet this 2 days ago
Follow @IVukic
Blessed Alojzije (Aloysius) Stepinac Feast Day February 10
Blessed Aloysius Stepinac quote:
“When they take everything from you, you’ll be left with two hands; put them together in prayer and then you’ll be the strongest.” Blessed Aloysius Stepinac (1898 – 1960)
First President of Croatia Dr Franjo Tudjman quote:
“They could not, nor will they ever be able to kill our passion and our need to live in human dignity, in peace with ourselves and with the free nations of Europe. We have carved out that right at our first democratic elections. For this right and for our sacred land we are even ready to die” – Dr Franjo Tudjman (1922-1999) ( Addressing the Croatian nation at the moment of the start of Serbian aggression against Croatia, 16 October 1991)
LINKS TO BOOKS
Ao only true men can: Nikola Zrinski’s Last Stand at Sziget by Zeljko Zidaric
Alojzije Stepinac: Pillar of Human Rights by Esther Gitman
BLANKA MATKOVIC ON COMMUNIST CRIMES – AMAZON, BOOK DEPOSITORY, BOOKTOPIA, BARNES AND NOBLE. BOOKS A MILLION …
LIVING CELLS – JULIENNE EDEN BUSIC – ON AMAZON
On Amazon & Createspace
pdf Public document
The Gospel of John, Ch.8,V.32
"and you will know the truth, and the truth will make you free."
Disclaimer, Terms and Conditions:
All content on “Croatia, the War, and the Future” blog is for informational purposes only. “Croatia, the War, and the Future” blog is not responsible for and expressly disclaims all liability for the interpretations and subsequent reactions of visitors or commenters either to this site or its associate Twitter account, @IVukic or its Facebook account. Comments on this website are the sole responsibility of their writers and the writer will take full responsibility, liability, and blame for any libel or litigation that results from something written in or as a direct result of something written in a comment. The nature of information provided on this website may be transitional and, therefore, accuracy, completeness, veracity, honesty, exactitude, factuality and politeness of comments are not guaranteed. This blog may contain hypertext links to other websites or webpages. “Croatia, the War, and the Future” does not control or guarantee the accuracy, relevance, timeliness or completeness of information on any other website or webpage. We do not endorse or accept any responsibility for any views expressed or products or services offered on outside sites, or the organisations sponsoring those sites, or the safety of linking to those sites. Comment Policy: Everyone is welcome and encouraged to voice their opinion regardless of identity, politics, ideology, religion or agreement with the subject in posts or other commentators. Personal or other criticism is acceptable as long as it is justified by facts, arguments or discussions of key issues. Comments that include profanity, offensive language and insults will be moderated.
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Fire Destroys Hudson Valley Animal Sanctuary
Bobby Welber
Arthur's Acres Animal Sanctuary/FB
A fire destroyed an animal sanctuary in the region. Donations are now being taken to help rebuild.
Download the Hudson Valley Post App
A fire ravaged Arthur's Acres Animal Sanctuary in Parksville Saturday night. Todd Friedman started the small pig sanctuary in Sullivan County just over a year ago. His goal was to rescue and rehabilitate animals that were "abused, exploited or discarded."
According to Friedman, the fire destroyed the pig barn, as well as what's described as "the big barn," the shed and parts the farm's trailer. The good news, all of the animals are safe.
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"We spent so much blood, sweat and tears turning it from a place of torture to a place of love and now it’s just ashes. This is just a bump in the road, we will rebuild and never stop fighting for the animals. Thank you all who have been here throughout the night fighting the fires and helping make sure the animals are safe," Friedman wrote on Facebook.
Arthur's Acres Animal Sanctuary is asking for donations as the rebuild.
"We are going to start working ASAP to rebuild," Friedman said. "It’s going to be hard but we are really good at hard, it’s going to be a struggle but we are good at that too."
You can donate by CLICKING HERE
Spot a typo? Let us know.
Read More From Hudson Valley Post
'Deadly' Drug-Resistant Superbug Spreading In Hudson Valley
Hudson Valley Doctor Accused of Stealing Millions From Patients
Newborn Baby Found Dead in Vacant Lot in Hudson Valley
New Details Surrounding Former Newburgh Teacher's Disappearance
Police Seek Help After Elderly Woman Raped in Newburgh
Help Needed In Finding Teen Who Went Missing From Dutchess County
Categories: Articles, Hudson Valley News, Sullivan County
DOWNLOAD THE HUDSON VALLEY POST MOBILE APP
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Lift and Transport Wire Mesh Panels with Ease
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SkyTrak® Telehandlers Get an Upgrade: JLG
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New Mid-Size Boom Lifts Waste no Time Getting the Job Done : JLG
Get a closer look at the improved multifunction capability and larger capacity of the new 460SJ and 450AJ boom lifts. Designed to increase productivity, the mid-size boom lifts also offer more durability and serviceability thanks to the new DuraTough hood design.
Nearly $223M in New Transportation Funding Approved
The newly allocated funding also includes $167.2 million from the State Highway Operation and Protection Program for 41 projects that will maintain and preserve the investment in the state highway system and its supporting infrastructure.
Continuing the push to rebuild and maintain California’s infrastructure, the California Transportation Commission (CTC) has allocated nearly $223 million to 108 transportation projects that will alleviate traffic delays, repair aging roads and bridges and encourage bicycling and walking.
Thirty-seven biking and pedestrian projects throughout the state will receive nearly $10.3 million in allocations from the Active Transportation Program.
“Allocations like those made today help Caltrans continue to invest in, maintain and modernize California’s transportation system,” said Caltrans Director Malcolm Dougherty. “Each of these projects is an opportunity to improve safety, access and mobility for all travelers in California, whether you choose to travel via car, bike or transit.”
The newly allocated funding also includes $167.2 million from the State Highway Operation and Protection Program for 41 projects that will maintain and preserve the investment in the state highway system and its supporting infrastructure. These capital improvements consist of projects covering maintenance, pavement repair and rehabilitation, safety improvements and upgrades to bridges throughout the state.
“Preventative maintenance is the most cost-effective means of protecting the state’s infrastructure investment,” continued Doughety. “We adopted a ‘fix it first’ strategy because for every $1 spent on preventative maintenance, we can save taxpayers up to $14 in monies that would have been spent on more expensive and extensive repairs.”
The allocations also include $2.2 million from Proposition 1B, a transportation bond approved by voters in 2006.
To date, more than $18 billion in Proposition 1B funds have been put to work statewide for transportation purposes. The remaining $43 million in allocations came from various state and federal transportation accounts.
Among the regional projects that received funding allocations were:
$2.3 million allocation to construct rumble strips, upgrade bridge railing, and enhance roadway striping along Interstate 8 (I-8), between Ballantyne Street and East Victoria Drive.
$1.9 million to reconstruct pedestrian facilities to meet Americans with Disabilities Act standards at 58 locations along Interstate 5 (I-5), and state Routes 54, 75, 78 and 115 in Imperial County.
$3.2 million to upgrade existing bridge rail end treatments at 40 locations on I-5, I-8 and state Route 52.
$3.1 million to seismically retrofit four bridges on Interstate 805 and on state Routes 94 and 125.
For more information, visit http://www.dot.ca.gov/hq/paffairs/news/pressrel/docs/May_CTC_projects.pdf.
Region: Western Edition | StoryID: 25711 | Published On: 7/13/2015
Source: http://www.constructionequipmentguide.com/Nearly-223M-in-New-Transportation-Funding-Approved/25711/
NFL Trivia Questions
Football season is gearing up!
Answer these questions correctly for a chance to win $100:
Who was the first defensive lineman to total 20 sacks in a season
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I-80 Forklift Service Truck Demonstration
Rick from I-80 Forklift goes over one of the well stocked service trucks they use to service and repair forklifts and equipment in the field. See more information at http://www.i80forklift.com
Lift Training Part 4
Genie lift training video
New Mid-Size Boom Lifts Waste no Time Getting the ...
Nearly $223M in New Transportation Funding Approve...
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Body & Health Conditions
What is a foodborne illness?
by Pete Campbell over a year ago
Foodborne diseases are those diseases that are contracted through the consumption of food or beverages contaminated with pathogens like viruses, bacteria, fungi and parasites. They are particularly common in the countries with poor sanitation standards and in developing countries.
What are the most common foodborne diseases?
Among all diseases that can be transmitted through contaminated food, the most common are those caused by campylobacter, salmonella and E. coli, which are all bacteria. Viral diseases caused by a group of viruses called calicivirus are also very common.
Campylobacter is a bacterium that causes gastrointestinal disturbances, such as abdominal pain and diarrhea, and it also causes fever. Campylobacter is the most common culprit among all the diarrheal diseases in the world.
Salmonella is also a very common bacterial foodborne disease. It causes salmonellosis, a disease characterized by diarrhea, cramps and fever. In people who have weaker immune system it can spread through the blood and cause very serious and potentially life-threatening infections.
E. coli, especially the type called E. coli O157:H7, is a bacterial disease associated with cattle. In humans, it causes severe diarrhea, often with blood in it, very intense stomach pain but little or no fever. In rare cases it can lead to a complication called hemolytic uremic syndrome.
Calicivirus, or Norwalk-like virus, is the most common viral foodborne disease. It can be difficult to diagnose because not many facilities have the required laboratory tests. It causes nausea and vomiting, rarely diarrhea, and usually resolves within two days.
It is estimated that each year in the United States 47.8 million people suffer from a foodborne disease. The number of registered cases in the United Kingdom is two million and in France 750.000 cases. In the United States, the disease that affected the most people is calicivirus, followed by salmonella, clostridium perfringens and campylobacter.
The foodborne disease with the highest death rate in the United States is salmonella, followed by toxoplasma gondii, listeria and norovirus.
Sources of foodborne illness
Many pathogens in comtaminated food can be killed by cooking or even refrigerating. For some of them, a very high or very low temperature is required. One of the most common sources of foodborne illnesses is raw meat and poultry. Undercooked meat is also a common source. Diseases transmitted through raw or undercooked meat and poultry include campylobacter, E. coli, salmonella and L. monocytogenes.
Other raw foods can also be the source of a foodborne disease. Unpasteurized milk and dairy products obtained from unpasteurized milk, especially soft cheeses, are particularly dangerous. These foods can be the source of salmonella, shigella, staphylococcus aureus, L. monocytogenes and C. jejuni.
Raw and undercooked eggs are associated with salmonella. Not many people actually eat whole raw eggs, but they are used in many dishes and kitchen products, such as mayonnaise, ice cream, tiramisu, frosting and various salad dressings.
Botulism is a disease caused by C. botulinum and its main source is improperly canned foods and salted or smoked fish.
Shellfish, especially undercooked and raw, can be the source of serious diseases caused by bacteria called Vibrio vulnificus and Vibrio parahaemolyticus.
When it comes to fruit and vegetables, they too can be a source of a foodborne illness, especially if they are used fresh. Pathogens that can be transmitted that way include salmonella, shigella, E. coli, L. monocytogenes and various viruses and parasites.
Diagnosis and treatment of foodborne diseases
In ideal cases, the diagnosis of foodborne diseases should be made based on specific laboratory tests. In those tests, a sample of blood, urine or feces is collected and culture tests are then made. Stool samples are required if doctors suspect the disease is caused by salmonella, E. coli and campylobacter. Stool samples are also used for examination under the microscope if a parasitic infection is suspected.
As for the viruses, they are more difficult to diagnose, because they are smaller and harder to culture. Instead, the samples are tested for genetic markers that indicate the presence of a virus.
However, there are many foodborne diseases that cannot be easily identified in the laboratory, since they require either expensive or highly specific tests that are rarely available in standard medical facilities. In addition, many foodborne diseases go undiagnosed because the patients do not report them.
As for the treatment, it varies, mostly according to the specific pathogen and on the symptoms. For many diseases, the treatment is focused on the symptoms. For example, if the primary symptom is diarrhea, which is also the most common symptom of foodborne diseases, is treated through rehydration, either oral or intravenous. Simple diarrhea can also be treated with Bismuth subsalicylate preparations, which reduce the severity and the duration.
Many bacterial foodborne diseases require treatment with antibiotics, based on the culture tests. Antibiotics are not suitable for viral diseases, which mostly go away on their own in a couple of days.
Prevention is very important when it comes to foodborne diseases. Good hygiene habits, careful handling of all foods, refrigeration and freezing, proper cooking at adequate high temperatures of all meats and poultry and avoiding foods from suspicious sources are very important. Cross-contamination can be avoided by keeping all the surfaces and items in the kitchen clean and sterile.
www.cdc.gov/foodsafety/foodborne-germs.html
medlineplus.gov/foodborneillness.html
Is It Salmonellosis Or Some Other Food Poisoning Bacteria?
Bacterial Food Poisoning
Acute food poisoning
Food microbiology - Microorganisms causing food spoilage
Salmonella is widespread foodborne illness
Lower intestinal infection
Intestinal infections in humans
Diarrhea from bacteria
Acute gastroenteritis facts
Signs of food poisoning in children
E coli and food poisoning signs
Causes of diarrhea
Campylobacter food poisoning
Diarrhea in babies while breastfeeding
How long does food poisoning last
Fourth Of July Barbecue Do's And Don'ts
The Truth About the European E. coli Outbreak
Don't Fall Victim To The Commonest Causes Of Food Poisoning
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Salmonella Food Poisoning: What Do You Need To Know?
Hand Sanitizer Vs. Soap And Water - Which Wins?
Diagnosis: Chronic Diarrhea
What Are The Chances Of Picking Up An Infection In A Public Restroom?
What Causes Hepatitis A, And How Can You Prevent It?
Bacteria And Viruses You Can Catch From Using Public Bathrooms
Hepatitis E Overview: Symptoms, Diagnosis, And Treatment
E. Coli - New Treatment Options
Hepatitis A Overview: Symptoms, Diagnosis, And Treatment
Tick Borne Rickettsial Disease
Side Effects of Imodium in Children
What kind of illness is listeriosis?
Can there be dehydration in food-born diseases
what are some real common disease that health proffessional
Chemicals in New Orleans bigger concern than cholera
growling stomach and diarrea
Diarrheagenic Escherichia coli
Is Chronic Diarrhea Serious?
Blood in Poop
E.Coli infection?
Raw milk helps fight autoimmune conditions?
Salmonella outbreak linked to peanut butter
Large Number of School Cafeterias Rarely Inspected
Viruses approved to be used as food additives
What types of food poisoning are there?
antibiotic resistence of enteric pathogens?
bloody diarrhea
In your opinion, is this the beginning of inflammatory bowel disease?
Diagnosed with trichomiosis
Why do vets question a raw food diet for dogs?
Campylobacter infections
E coli in a trac tube
My sister has Hot n Cold Flashes,Vomiting,Dirrahrea,Stomach Pains
Stomach infection
symtoms of ecoili
ECOILI AFTER SURGERY
ECOILI EFFECTS
prevention of campilobacter
bacteria in the stomach
Shigella Infection symptoms
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Icy News: VMware pushing Windows apps to any device
"LAS VEGAS--Pressing its case that the desktop is moving away from the center of computing, VMware Chief Technology Officer Steve Herrod gave attendees at the annual VMworld conference here today a glimpse at a technology the company is developing that will let workers access Windows applications regardless of the type of device they're using or the operating system it runs.
Herrod built on the post-PC era theme VMware's Chief Executive Paul Maritz laid out in his keynote address at the conference yesterday. Herrod showed off technology from VMware's labs, some of which is being released today, that lets corporate tech managers simply provision applications--such as Microsoft's Excel spreadsheet software--to employees to use on iPads, Android phones, as well as their Windows desktops.
"The world has changed," Herrod said of the era when IT managers doled out applications to PCs, which were then handed to employees. VMware is introducing technology that lets those manager "apply policy based on humans rather than devices," Herrod said.
VMware updated its Horizon Application Manager, which had only let users run cloud-based applications, to support Windows applications regardless of the type of device or the underlying operating system. Herrod also demonstrated ThinApp Factory, which lets employees pick among the applications that their tech departments make available to them. Companies can stitch those together with VMware's Horizon Mobile to make those applications easy to use on portable devices. And VMware announced that devices running Horizon Mobile will be coming from LG and Samsung, among others, in the coming months.
Herrod also previewed VMware's Project AppBlast a service that promises to deliver any application, including ones created for Windows, to any device supporting HTML5. And he demonstrated Project Octopus, a service that synchronizes data to enable collaboration over any device. He didn't disclose when either project would be available.
The idea is to free IT departments from the hassle of granting employees access to specific applications for every device they use. At the same time, it should make it easy for those workers to run a corporate application on whatever device they have in front of them.
In the demonstration, VMware showed an insurance adjuster selecting the apps he needed to do his job from his desktop computer, then finding those same apps running on his mobile phone using Google's Android operating system and later settling a claim from his iPad. And the adjuster was able to view and modify an Excel spreadsheet from his iPad.
"This is really a killer app in the labs," Herrod said. "I think it's going to be quite disruptive."
What's more, the technology keeps the corporate workspace separate from a user's personal apps. On the Android device, for example, the adjusters Facebook and Angry Birds apps remained on his home screen. The phone only changed to his digital workspace when he tapped on the corporate icon on his phone. That separation should also make it easy for IT departments to remove their programs when the employee leaves the company.
Read more: here" via - news.cnet.com
VMware seems to be really on to something with pushing Windows apps to any device. VMware has usually been in the Enterprise Market with their very popular software but, now they can possibly reach into the consumer market widening their reach on the software market. Let us know what you think about this new idea VMware has come up with and do you see it being used in your life?
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Parliamentarians learn about ground-breaking science on debilitating neurological disease
In parliament house in Canberra yesterday, members of federal parliament took the time to listen to world renowned scientists and their ground-breaking findings that explain the debilitating disease myalgic encephalomyelitis, a type of chronic fatigue syndrome. The event focused on a presentation by Griffith University Professors Don Staines and Sonya Marshall-Gradisnik.
The turnout was particularly impressive given the leadership turmoils occupying the headlines and the minds of so many people working in the building. Jokes were made at the beginning and end of the event, confirming that Malcom Turnbull was still the Prime Minister.
The event was hosted by the new Parliamentary Friends of ME/CFS, founded by Greens Senator for Western Australia, Jordon Steele-John and co-chaired by Labor Senator for Queensland, Claire Moore and Liberal Senator for Tasmania Jonathon Duniam.
A range of parliamentarians from across the political spectrum, in both the House of Representatives and the Senate attended, as did policy advisors, members of the academic community, patients and advocates.
Senators Andrew Bartlett, Greens for Queensland; Slade Brockman, Liberal for Western Australia; Jonathon Duniam, Liberal for Tasmania; Jordon Steele-John, Greens for Western Australia; and Claire Moore, Labor for Queensland all attended.
From the House of Representatives, Liberal Member for Dunkley, Chris Crewther; and Labor Member for Canberra, Gai Brodtmann attended. Up to a dozen policy advisors attended from a range of parliamentary officers.
Jordon Steele-John welcomed everyone to the event. Jonathon Duniam introduced the speakers. Don Staines began Griffith’s presentation with some poignant insights into why their research mattered. “It is an honour to present to the representatives of the people, our novel scientific findings” he said. ME/CFS is “a very silent illness, because people are often unable to represent their needs”.
In unpacking the approach of the National Centre for Neuroimmunology and Emerging Diseases, he explained that “the existing science is not yet up to it.” “Patients have experienced extreme stigma and discrimination associated with the lack of known biology”. The aim of the centre’s work was to reduce this stigma by demonstrating the biology of the disease, developing a diagnostic test and identifying therapeutic drugs to manage the disease. He spoke plainly and eloquently for all to understand the gravity of what he was saying.
Sonya Marshall-Gradisnik went through a summary of all the research they have done in three years, explaining what and how they have come to understand the pathology of the disease.
First, they identified a family of genes significantly associated with the disease. Then, they tested these genes, the family of TRPM3 markers, for changes in expression between healthy controls and patients with ME. This gene is found in cells in the central nervous, cardiovascular, digestive, endocrine, immune and excretory and other systems in the body. In this way, they came to understand how so many systems in the body are affected by the disease.
What they found was that the cells containing TRPM3 showed a reduced capacity for the transfer of calcium ions between and within the cells. Calcium ions are vital to cellular energy transfer and proper cell function.
By using gold standard technological processes, they measured the amount of calcium that is stored by and circulated in particular cells. Again, in ME patients, these rates were significantly lower than in healthy controls. This science would explain why many patients describe their experiences as like running on a faulty cellphone battery that doesn’t charge properly and never fully recharges.
TRPM3 are threat receptors. They are triggered by infections (bacterial or viral), perfumes or other chemicals, cell stretching or stress, temperature variation and a range of other factors. This not only explains some of the onset factors for ME, but also some of the triggers patients experience after contracting the disease.
Don Staines explained that, given these findings, we could see that “recommendations to exercise patients are wrong” because it only places greater demand for calcium ions in the cells. This also explains why patients who meet the diagnostic criteria defined in the Canadian Consensus Criteria or the International Consensus Primer would in fact be worsened by a regime of Graduated Exercise Therapy. While patients who experienced the symptom of chronic fatigue without meeting these criteria may experience some improvement.
As for recommendations to treat patients with Cognitive Behaviour Therapy, Sonya Marshall-Gradisnik said she was “not aware of any psychological treatment that can effect calcium ion transmitters”.
Attendees were keen to know what policy makers could do to help researchers and patients. The sample sizes of the studies undertaking so far were about 200 people. To allow all Australian patients to contribute to the study (and vastly increase the value of the science by increasing the sample size), the centre will need $13 million. So far, they have raised half of this money through philanthropic donations. They asked the parliamentarians to support federal government funding for the remaining $6.5 million.
Recommendations also came to ensure government policies and guidelines are updated to account for this research, helping reduce the personal, financial and social burden of the disease on patients. While no specific mention was made of the National Disability Insurance Scheme or Disability Support Pension, ongoing discussions will address some of these issues. There was, however, an explicit call to remove GET and CBT recommendations from policies including guidelines of the Royal Australian College of General Practitioners.
While Don and Sonya were loathe to provide timelines on their advances for diagnostic testing and therapeutic drugs, they explained they were working with a leading Australian pathology service provider with a timeline of three years for both projects.
At the end of proceedings Claire Moore closed the event with a call to action for policy makers while paying tribute to the good work that Scott Ludlum had done in this space. Significant networking between parliamentarians, policy advisors, other researchers and patients occurred before everyone dispersed. Overall, it was an incredibly worthwhile event and impressively successful, especially given the amount of attention being diverted for leadership contentions within the government.
Posted on August 22, 2018 August 23, 2018 by Susan This entry was tagged disability. Bookmark the permalink.
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12 thoughts on “Parliamentarians learn about ground-breaking science on debilitating neurological disease”
Jenny Meagher says:
Thank you Susan for providing the detailed report of the meeting. It is useful to know which MPs and Senators attended so that they can be thanked.The networking following the presentation sounds promising. Policy makers are increasingly taking our disease seriously. We need to keep in mind that both Claire Moore and Andrew Bartlett are retiring at the next election.
Ketra says:
A great detailed summary of NCNED’s progress and why we need new guidelines for ME/CFS. Thank you Susan.
Thanks Ketra
Elina Lintunen says:
Thank you for this very comprehensive debrief of the meeting. No wonder you’ve crashed Susan, sending you best. I did send a request to the then Health Minister & hope that one of his policy advisers was in attendance. Although I don’t know him personally we have an important mutual connection.
Kim Wilson says:
That was so exciting. Thank you Susan for attending and explaining how things went. I would not have known about this without your post and it’s very encouraging to know politicians are hearing about our battle
Hal Drabsch says:
Thank you Susan for attending this presentation by Griffith University Professors Don Staines and Sonya Marshall-Gradisnik, in parliament house Canberra, and for sharing the report.
JUDY WICKERT says:
I have me/cfs…genetic testing “saved” me (holisticheal.com). Since M.E. is brain inflammation, consider the work by Dr.Dale,Breseden,MD (bk; The End of Alzheimers) and his ReCODE protocol. My mother had dementia, and now me. THESE THINGS CROSS OVER.
mimb says:
This seems to confirm the work of Prof Martin Pall done almost 15 yrs ago now but from a different angle. [For Prof Pall’s work see – https://web.archive.org/web/20150315143107/http://www.thetenthparadigm.org:80/index.html%5D
admindxrw says:
Thank you for this report, Susan.
For the International Edition of SNOMED CT, Chronic fatigue syndrome and its Synonyms terms are now located under the parent: Disorder of nervous system. This change was implemented for the July 31 release. The Australian National Edition of SNOMED CT will incorporate this change on December 30.
Report: https://dxrevisionwatch.com/2018/08/01/chronic-fatigue-syndrome-classified-under-neurological-disorder-in-snomed-ct-international-edition/
Excellent news and blog.
Low sample sizes has always been the main issue with the NCNED team’s work, and increasing the sample sizes is the most important step they need to take, and that means increased funding. So it is very good to read this bit:
Thank you to all who organised this, and attended. The cross-party political involvement and support is particularly encouraging. 🙂
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Pingback: Advocacy Roundup - Holding Our Institutions Accountable - #MEAction
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Smooth sailing for top seeds in Tahiti
Host nation’s Alize Belrose in action
The top seeds have made it through to the quarterfinals unscathed at the 2019 ITTF Oceania Tour in Tahiti. Competition officially kicked off today in heart of Tahiti with over 50 athletes fighting for a place in the quarterfinals.
In the Men’s Singles, 2018 Pacific Cup finalist Yoshua Shing of Vanuatu cruised through the group stage without dropping a single set. He will be taking on host nation’s Matahi Tarano tomorrow in the quarterfinals. It will definitely be a tough match for Tarano but the Tahitian with home turf advantage will definitely be looking to challenge the Oceania star tomorrow.
Tahiti star and second seed Alize Belrose followed in Shing’s footsteps and cruised through his matches on day 1 with a clean sheet. Following his brother Ocean Belrose’s win at last years ITTF Oceania Tour in Tahiti, Alize will be heading into matches tomorrow with his eye on the title to continue the Belrose legacy.
In the Women’s Singles, Australia’s Olympian and Paralympian star Melissa Tapper dominated in the group stage, dismantling all her opponents 3-0. Tapper will be looking to make her mark in Tahiti as preparation for the Oceania Olympic Team Trials in a month’s time.
With $7600 in prize money, the most of any 2019 Oceania Tours and one of the last opportunities to earn ranking points to qualify for the 2020 Oceania Cup, tomorrow’s matches will be a treat for all table tennis fans. Make sure you tune in to watch LIVE on our Facebook!
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Research Article| February 01 2004
Application of TAML® catalysts to remove colour from pulp and paper mill effluents
K.G. Wingate
New Zealand Forest Research Institute, Private Bag 3020, Rotorua 3201, New Zealand (E-mail: kate.wingate@forestresearch.co.nz)
E-mail: kate.wingate@forestresearch.co.nz
T.R. Stuthridge
New Zealand Forest Research Institute, Private Bag 3020, Rotorua 3201, New Zealand (E-mail: trevor.stuthridge@forestresearch.co.nz)
L.J. Wright
Department of Chemistry, The University of Auckland, Private Bag 92019, Auckland 1020, New Zealand (E-mail: LJ.Wright@auckland.ac.nz)
C.P. Horwitz
Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA (E-mail: horwitz@andrew.cmu.edu)
T.J. Collins
Department of Chemistry, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, PA 15213, USA (E-mail: tc1u@andrew.cmu.edu)
Water Sci Technol (2004) 49 (4): 255–260.
https://doi.org/10.2166/wst.2004.0277
K.G. Wingate, T.R. Stuthridge, L.J. Wright, C.P. Horwitz, T.J. Collins; Application of TAML® catalysts to remove colour from pulp and paper mill effluents. Water Sci Technol 1 February 2004; 49 (4): 255–260. doi: https://doi.org/10.2166/wst.2004.0277
A TAML® catalyst (0.5 μM, 0.23 mg/L of effluent) combined with hydrogen peroxide (6.5 mM, 0.19 g/L of effluent) were capable of permanently removing 46% of the colour from bleach plant effluent (Eop, pine-derived) in one hour at 5,000 L effluent per day. Increasing concentrations to 2 μM catalyst (0.9 mg/L of effluent) and 22 mM peroxide (0.75 g/L of effluent), resulted in removal of 78% of the colour. In addition, 29% of the chlorinated organic material (AOX) was also removed. A laboratory investigation indicated that the oxidative process predominantly removed phenolic structures. The low aromatic content of the effluent meant that the majority of the organic material was not substantially altered during treatment. Thus chemical oxygen demand was essentially unchanged. This technology was able to remediate colour from effluents derived from both softwood (pine) and hardwood (eucalypt). Laboratory studies on catalyst life-time during effluent treatment, demonstrated that activity was maintained for a sufficient period to eliminate all the chromophore available to the active species, but that the catalyst did not survive long enough to be discharged into the receiving environment. Microtox tests showed that catalyst degradation products were not toxic to the receiving environment.
AOX, catalyst, decolorization, effluent, hydrogen peroxide, wastewater
Email address / Username ?
Hydrogen production from coffee pulp by dark fermentation
Granular computing-neural network model for prediction of longitudinal dispersion coefficients in rivers
Purification of real car wash wastewater with complex coagulation/flocculation methods using polyaluminum chloride, polyelectrolyte, clay mineral and cationic surfactant
Research on the coagulant aids effects of modified diatomite on coal microbial flocculation
Nutrient removal efficiency of green algal strains at high phosphate concentrations
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Barefoot challenge for former Girlguide
Girlguiding IW played host to one of Girlguiding’s national ambassadors with Anna McNuff’s visit to the Island.
Anna is an endurance athlete, adventurer and speaker and this year her latest challenge has been to try and run the distance of 100 Marathons (2,620 miles) barefoot through Britain.
Her ‘Barefoot Britain’ challenge started in the Shetland Islands on Sunday, June 2 and ends in London on Sunday, November 17. A route including Scotland, NI, Wales and the Channel Islands has been undertaken prior to the visit here.
She visited the Isle of Wight as part of her challenge, travelling here with Red Funnel. This followed a run from Lymington to the outskirts of Southampton on the previous Friday.
Anna was greeted in St. Thomas’ Square, Newport by Guide Section Commissioner Linda Stone and Brownie Katie Wells and a Guide Keira Wells who, along with other supporters ran with Anna at the start of her route to Ryde.
Some of the other runners ran with Anna to Shanklin and others joined in along the way. One runner joined Anna for the 20+ mile run on the Island which finished on Ryde Esplanade. This run used, in the main, the cycle ways and footpaths.
Girlguiding IW members were invited to join Anna as part of this adventure by attending a talk at The Bay CE School, Sandown. Here, Anna regaled her audience of Brownies, Guides Girlguiding IW leaders and other supporters with her exploits and spoke on her previous adventures in South America, The USA, where she visited every state, and her favourite destination, New Zealand.
Details of these exploits plus those encountered in ‘Barefoot Britain’ made for a very entertaining evening which the audience enjoyed. Anna’s talk was followed by a Q & A session.
Anna’s main thrust of the talk was ‘Be Yourself’ saying, “Do not worry about starting things that you think you can’t finish. You usually do manage to finish them.”
Having been a Rainbow, Brownie and Guide in London Anna has been only too pleased to support Girlguiding, the leading charity in the UK for girls and young women, by undertaking this challenge.
Tweets by iwobserver
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Jaime Dunkle
Love harder when you're mad.
Love in a Plain Brown Envelope
Cry, Baby, Cry
My So-Called Cousin
Ca$h Me Ousside, Literally
Fear & Safety in the First Circuit
Shadowboxing Emotional Biases
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Cheyenne, Bertha, and Ca$h Me Out Carl
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Rat Face and Ass Licker
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Chalice II and Daniel
Chalice II
A tiny blue bag of off-white powder sits next to tubes of lipstick and expensive non-synthetic brushes in Chalice’s open metal make-up case on the counter of her station in the dressing room.
She teeters over to my station in black vinyl six-inch heels, which make her tower over everyone at a total of six feet and four inches.
The silver glitter specks on her minidress twinkle like stars across deep space.
“Can I borrow your Skinny Puppy Last Rites CD?”
I smile. It’s 1999 and we’re the only strippers we know who have the guts to dance to industrial.
“Of course,” I say as I dig it out of my bag.
“Come over to the house tonight,” she says. “Let’s party”
She dangles the bag of MDMA powder from her long, manicured fingers, then sets it down.
Before I can answer, she runs up the stairs. Each step exhibits the grace of a cheetah.
I hadn’t done any variation of ecstasy in years, but I knew I had to join her.
We sit on the floor at the edge of the bed that’s now hers. My face flushes and my palms itch.
Chalice hands me a mirror with a thin MDMA line spread across it like a stratus cloud across an afternoon sky. I stare at it and fidget with my own cut straw in my hand.
“Don’t tell me you’re having second thoughts,” Pharaoh says and bats his natural half-inch eyelashes. He’s my ex, and Chalice just moved in with him.
He’s right. I’m reluctant because I remember the last time we partied when he had a girlfriend, before our first failed—and brief—dating stint. Somehow we willed an orgy with our mind—so we thought—so that we could have an excuse to make out in front of his girlfriend at the time. Neither he nor myself partook in the evening’s sexcapades. Instead, we glanced over as we passed the writhing bodies in the living room and hall on the way to the bedroom, where his girlfriend found us. The three of us ended up in bed together, but his girlfriend fell asleep. He left her for me. Then he left me for drugs. I figured he and Chalice were a good fit since drugs was their thing.
I plug one nostril and plunge into the line. The powder burns my nose and tastes sour as it clots down my throat in bitter chunks.
“Good goddamn,” I say as I snort louder than a walrus.
Chalice grabs me by the hands and leads me toward the dresser. We stand together in the doorway of the bedroom.
“Do some magick,” she says. “Like you do with the O.T.O.”
I don’t respond with words. I close my eyes. So does she. We press our foreheads together under the door frame.
The Egyptian goddess Nuit arches across my mind as outer space bejeweled with stars and planets. In my mind, I recite the lines of the priestess role in the Gnostic Mass:
But to love me is better than all things; if under the night-stars in the desert thou presently burnest mine incense before me, invoking me with a pure heart, and the serpent flame therein, thou shalt come a little to lie in my bosom. For one kiss wilt thou then be willing to give all; but whoso gives one particle of dust shall lose all in that hour. Ye shall gather goods and store of women and spices; ye shall wear rich jewels; ye shall exceed the nations of the earth in splendour and pride; but always in the love of me, and so shall ye come to my joy. I charge you earnestly to come before me in a single robe, and covered with a rich head-dress. I love you! I yearn to you! Pale or purple, veiled or voluptuous, I who am all pleasure and purple, and drunkenness of the innermost sense, desire you. Put on the wings, and arouse the coiled splendour within you: come unto me!” [Liber AL, I:61] “To me! To me!” [Liber AL, I:62] “Sing the rapturous love-song unto me! Burn to me perfumes! Wear to me jewels! Drink to me, for I love you! I love you. I am the blue-lidded daughter of sunset; I am the naked brilliance of the voluptuous night-sky. To me! To me! [Liber AL, I:63-65]
Chalice pulls away with tears in her eyes. She slumps on the bed.
“I saw her,” she says.
“Who?” I ask.
“The goddess of space,” she says, although I told her nothing about who or what I was invoking.
“Her name is Nuit. She’s Egyptian. I said her prayer from the Book of the Law.” I say, and sit next to her on the bed.
“Thank you,” she says with her arms wrapped around me. She weeps.
Daniel from Cash Me Ousside Booking Agency hires me to book strippers when he finds out I’m eager to get out of stripping.
Some stripper shifts start as early as 7 a.m., if you can imagine that. A few steak joints in the ‘burbs open that early. The dancers are almost always late, except the older women, and by older I mean they’re in their 40s to 60s.
But I don’t deal with those problems because I arrive at the office at 9 a.m., and by then Daniel practically has three phone cords wrapped around his neck like a telecomm noose. His face a permanent beet red. His office desk covered in weed, post-its and empty water bottles.
“You want to work nights this weekend? Then get your lazy ass up and get to the club NOW,” Daniel says into the receiver and stands up, his eyes glazed and bloodshot. “You’re already 30 minutes late.”
He slams the phone down, grabs the bong, takes a hit standing up. He coughs for a solid minute, his face a bruised purple as mucus flies from his mouth. He sits back down at his desk and loads the bowl, hands me the bong. He grabs a pad of paper with a list of dancer’s phone numbers.
“We need to send someone else there, just in case. Start calling,” he says.
I take a modest hit. Exhale. I study the texture of legal pad paper between my fingers. I read the list aloud.
“Jasmine, Diamond, Star, Athena, Destiny, Amber, Gypsy, Rose, Luna, Misty, Brandi, Nikki, Hunter, Brittany, Alice, Hannah, Gia, Maddie, Shelby, Lily.”
We both laugh. The smoke still lingers over our heads.
“But what if the scheduled girl goes in?” I ask.
“We’ll have to either send whoever gets there second home, or convince the club to let them both stay.” He says.
“So I’m going to piss someone off, either way.” I say.
“Basically,” he says. “Welcome to hell.” He takes another bong rip as I dial numbers on the landline.
These stories originally appeared in Exotic Magazine, April 2017.
Mouth of Madness
Portland 🙏
Comfort zone. View from Salmon Street.
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Disney pays $23 million for 1,000 acres of land near Celebration
in Disney, Walt Disney World
Posted on December 17, 2018 by Bailee Abell
Walt Disney World Company just paid approximately $23 million for just under 1,000 acres of land near Celebration, FL, the Orlando Sentinel reported. The 965 acres of land southeast of Celebration — the town adjacent to Walt Disney World Resort property — is known as BK Ranch in Osceola County.
Disney isn’t the only company who planned to develop the BK Ranch land. The land, which is zoned for development off the old Tampa highway, was originally planned to be developed into 3,000 homes and 378,000 square feet of office and commercial space. Given the land’s close proximity to the town of Celebration, BK Ranch, once developed into a community, could have rivaled Celebration, if it had been developed years ago. Now that Walt Disney World has purchased it, the future of the land and its development is up to Disney.
Image source GrowthSpotter
While fans may speculate about the future of this land, it isn’t likely that we will hear about its development anytime soon, as Disney has yet to comment on the purchase of BK Ranch, let alone their plans for it. Westhampton Realty owner and broker Jerry McGratty said to GrowthSpotter that Disney was primarily interested in acquiring the almost-1,000 acres of land for “water management needs” and conservation, so it is likely that little will come of it. McGratty stated, “I do not believe they will ever develop it.” Whether McGratty’s opinion holds true, only time will tell.
It is true that Walt Disney World may be inclined to use the BK Ranch land to manage the current water and conservation of their existing theme park and resort properties. But with the purchase of such a large number of acres (Magic Kingdom alone is just under 150 acres large) and Disney’s recent expansion of multiple of their theme parks and resorts, fans can only speculate about the future of the land and whether an even larger expansion could be in the cards for the Disney property.
We will continue to update this story as more information becomes available.
What do you think of Walt Disney World’s newest land purchase? Let us know in the comments!
Source: Orlando Sentinel, GrowthSpotter
Tagged:celebrationDisneyWalt Disney World
Disney-Fox merger causes concern in Latin America due to control of sports channels
Posted on December 17, 2018 by Cristina Sanza
Take a photo with Rapunzel’s lantern and more glowing props right now at Walt Disney World
Comments Off on Disney pays $23 million for 1,000 acres of land near Celebration
Older Older post: Disney-Fox merger causes concern in Latin America due to control of sports channels
Newer Newer post: Disney+ picks up rights to new young adult novel from “Descendants” author Melissa de la Cruz
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Teach English Overseas Archives
Why American Expats are Flocking to Spain for Livelihood
By Koren Helbig |
With almost perpetually sunny weather, glittering stretches of Mediterranean coastline, and a relaxed, easygoing lifestyle, Spain has long been a favorite playground for Americans on vacation. But plenty of business-savvy Americans are extending that vacation into a way of life, and making a prosperous living here, too. In a country where even the Prime Minister struggles to speak English, locals are only too aware of the need to improve, meaning native speakers can easily find work as English teachers and translators.
Read More : Why American Expats are Flocking to Spain for Livelihood
Opportunities for Making Good Money in Costa Rica
By Jason Holland |
When Costa Rica got its start as an expat haven more than three decades ago, it was all about retirees. But over the years, the great weather, stable government, and low cost of living have also attracted those too young to retire (or those who never want to). And they've found plenty of ways to support themselves—and their families—while living in a tropical paradise.
Read More : Opportunities for Making Good Money in Costa Rica
6 Reasons Why Teaching English is For You
By Kary Vannice |
As I'm sure you know by now, you already have a skill that can easily translate into a steady income in a foreign country...English. In fact, thousands of people just like you have already used the fact that they speak English fluently to become English teachers in exotic new countries. Here's why you should join them: In nearly every country on the planet there's a huge number of people who want to learn English.
Read More : 6 Reasons Why Teaching English is For You
Spanish Tapas, Flamenco Dancing…and an Easy Income
By Tara Lowry |
Stomping my feet as hard as I could, I twirled around in a frenzy, flailing my arms and yelling before coming to a standstill next to the dark haired woman in front of me. "Bien." She clapped her hands once and then left the room. I smiled as the guitar player and other students picked up water bottles and wiped down their foreheads with small towels. I was in Seville, Spain, and having the time of my life learning to dance flamenco.
Read More : Spanish Tapas, Flamenco Dancing…and an Easy Income
Getting Paid to Teach English in France
By Bonnie Caton |
Gliding between the jagged peaks of the French Pyrenees in my chairlift seat, I took a deep breath and tried to relax. It wasn't the soaring height of the peaks that made me nervous, or the prospect of swishing down them on my skis. It wasn't the weather, either—blue skies stretched from peak to peak. Nope, everything on the slopes was perfect.
Read More : Getting Paid to Teach English in France
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Home » Latest » An Exploration Station Has Landed At Lab Live
This weekend at Lab Live: Curiosity with OKIDO we’re inviting young scientists and astronauts to come up with ideas for the Exploration Station and invent their very own Exploration Rover inspired by NASA’s Mars Curiosity Rover.
Why is curiosity important for space exploration?
NASA launched the Curiosity Rover on 26 November 2011 and it landed on Mars in August 5 2012. The Curiosity was charged with the mission to answer one question: Did Mars ever have the right environmental conditions to support small life forms called microbes? It is the largest and most advanced Exploration Rover to ever be sent to Mars and since then it’s made amazing discoveries.
Here are some of the incredible discoveries that the Curiosity Rover has made so far:
Evidence of ancient water flows
Curiosity found rocks believed to have been eroded by ancient waterflows. The layers of exposed bedrock reveal to scientists that there may have once been a stream.
Curiosity has detected dangerous levels of radiation
Exceeding NASA’s career limit for astronauts.
Methane Mystery
In September 2013, NASA noted that the Rover had not found a single trace of methane in the Martian atmosphere. However, since then it’s found that the Red Planet has background levels of Methane, that peak depending on what season it is.
Ancient Mars could have held life
Thanks to Curiosity scientists now know that Mars likely had the right chemistry to support living microbes.
Curious to find out more about the Curiosity Rover and its mission? Check out this awesome resource from NASA.
Join a mission to outer space
Sound’s exciting doesn’t it?
Well, are you ready to join us on our very own space mission? Discover the Exploration Station, built by the mysterious alien artist Chris Gilmour on an Exoplanet 2.5 light years from Earth.
The state-of-the-art extragalactic research station will have everything you need to research this new and strange planet. Surrounded by space books from DK Books, curious videos and roaming scientists, as a family you’ll be able to research questions like; what do we already know about outer space? What will we need to live on this planet? Are there moons and stars in the sky? Plus you can design and build your own additions to the Exploration Station.
Not only will you have the chance to add to the visionary research station, but you can also build a mini Exploration Rover, inspired by the Curiosity Rover. Using cardboard, crafts and elastic band-powered prolusion, you can design a prototype, then build and test it.
These activities develop an interest in engineering and exploration, by working as a team with family and new friends – drawing, inventing and making in preparation for the mission of a lifetime. You can bring innovation and creativity to the Exploration Station, who knows what we’ll discover by the end of the day!
To join the mission, get your tickets for Lab Live: Curiosity with OKIDO for this weekend, 18 & 19 May.
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Congratulations to Lisa Carrington on achieving her double victory in Milan!
After five days of intense racing, the Kiwi team can celebrate some amazing results from the ladies. Lisa Carrington has achieved her ambitious goal of a win in both the Women's K1 200m and 500m categories.
The list of Carrington's milestones is significant. With her two gold medals this year, Carrington overtakes Paul MacDonald as New Zealand's most successful world championship athlete, with five. She joins MacDonald as the only Kiwi to win two golds at the same championship and she is the first woman in 16 years - and only the third in history - to hold both the 200m and 500m titles at the same time.
Canoe Racing NZ
She is a fantastic ambassador for Nelo Kayaks and Jantex Paddles. We congratulate Lisa on her historic victory! You can see the race here at about 10 minutes in.
The Women's K4 team has also succeeded in meeting the Olympic Standard and will likely be included in the NZ Olympic Team at Rio 2016. They finished in ninth place overall. They're the first NZ Women's K4 team to make the standard and, if confirmed in the Olympic team early next year, the current crew will more than double the number of females to have competed at that level. What an exciting time for NZ Women in sport.
Meanwhile, the men raced with heart but will have to compete at the Oceania Champs for their tickets to Rio. Scott Martlew placed first in the B Final of the K1 Mens 200m KL3 division, making him the tenth fastest on the day. The Men's K2 Team of Zac Franich and Darryl Fitzgerald improved a lot over the course of the competition; they placed seventh in the Mens K2 500m C Final. Marty McDowell was eliminated in the heats of his Men's K1 1000m competition, just missing out on a place in the Semi-finals.
Overall, it was a great week of racing with encouraging improvements by all the NZ Team members. The training schedules for the Oceania Champs will be intense for this group of athletes who looked focussed on their goal – making it to the Olympics in Rio 2016. Hats off to Lisa Carrington yet again, a true hero of our sport.
Wednesday’s Racing
Scott Martlew fought hard to come third in a tough semifinal, but unfortunately in the end he was just 0.45 seconds off making the A final. He'll be racing in the B Final of the K1 Mens 200m KL3 on Friday. Hopefully a good finish will restore his confidence in getting a shot at Rio, as he could still take one of the four spots up for grabs at next years the World Champs in Germany.
"I was disappointed with my result today - I just missed out on that A final and I'm frustrated that I miss out on chasing that top-six spot for qualification but I've got a crack at the B final, so hopefully I'll be able to improve my racing before then," he said.
Thursday’s Racing
Lisa Carrington cruised into the finals of the Women's K1 500m, with her semi-final time beating her heat time by 5 seconds. In the other semis, Hungarian Anna Kárász was the quickest qualifier for Saturday's final with a 1:48.113 effort, as Great Britain's Rachel Cawthorn (1:48.750) and China's Yu Zhou (1:48.813) also went quicker than the Kiwi. It will be fascinating to see how quick she can be when pushed.
Meanwhile it was brutal day for the boys, with Marty McDowell missing out on the K1 1000m semi-finals by placing sixth in the fastest heat of the day. His 3:40.005 time would've got him through comfortably in four of the other six heats.
Zac Franich and Darryl Fitzgerald finishing sixth in their K2 1000m semi-final, putting them in Saturday's C final, with a chance to break into the top-20 in the world. It was a tight category, with the top 12 K2 crews all within 3secs of each other. Their 3:18.344 semi-final effort as a seven second improvement on their heat time and pout them 10 seconds behind the top 12. An encouraging improvement nonetheless.
Friday’s Racing
Scott Martlew has won his KL3 200m B Final, a great result that he deserves to be proud of. His placing and his time make him number 10 in the World. He had narrowly missed out on making the A final. Watch the replay here, his race starts at about 16 minutes in. He finished in 42.434secs, edging Spain's Jonas Garcia by 0.338, with the top five paddlers finishing in a tight group.
Lisa comfortably won her Womens K1 200m semifinal in a time of 40.330 seconds, the fastest qualifier.
The Women's K4 team qualified for the K4 500m Final A final by placing second in their semi-final. Jaimee Lovett, Caitlin Ryan, Aimee Fisher and Kayla Imrie led for most of the 500m distance, but were pipped at the post by the Polish crew who finished in 1min 34.092secs. New Zealand clocked 1:34.892 for the eight-fastest time overall.
Saturday’s Racing
Lisa Carrington blew away the competition in the Women’s K1 500 metre A final, shining in a stellar field of high performance athletes. She looked focused, in full control from the start and steadily pulled away from the competition to lead by half a boat length at half way. Digging deep over the last 100m, Lisa tore away from the competition to finish over a boat length in front of fastest qualifier Anna Kárász of Hungary and Yu Zhou of China. It was a joy to watch the distinctive koru on her custom-painted K1 Nelo Cinco power away!
"I had an idea I was in the lead but I couldn’t back off it at any stage," a glowing Lisa said. "It was a tough race and I had to be really prepared to give it everything and do what I could because the competition was so strong. I couldn't leave anything up to chance. I'm just really pleased to get the K1 500m done and now I can refocus on the 200m."
Her winning time of 1:49.398 seconds placed her 1.727 seconds clear of rising Hungarian star Anna Kárász, with surprise third in Yu Zhou. The win makes her only the second non-European to win the 500m title, after Canada's Caroline Brunet from 1997-99. You can watch the replay here.
It was fantastic to see Lisa achieving this important milestone: she was clearly chuffed to get her ticket to Rio. But more than that, by convincingly winning the 500m – the distance that is not her strongest – she has the achieved the most ambitious part of her plan to hold both the K1 500m and 200m titles.
She is the clear favourite to win the K1 200m A Final tonight, having qualifying fastest and on a winning streak of three consecutive titles.
"It's all about keeping the challenge and trying to get better and better every year and every day. It's allowed me to become a better paddler and, as I get older, I seem to get fitter and stronger and work on more things." she said.
The K4 women also did their country proud, finishing third in their Womens K4 500m semi-final to book a place in the A final – and their ticket to Rio.
Great Britain and Germany overhauled the Kiwis in the last 50m, clocking 1min 33.635secs and 1:33.70secs respectively, but the New Zealand crew were only 0.308secs behind.
"I guess there's a pretty high likelihood we'll go to Rio now, which is a bit of a dream come true," a jubilant Fisher said. "It's been a pretty long year and there's been a lot of suffering together. It's been a year of hurting but it's all really paying off now."
Although they have only been training together for nine months, Jaimee Lovett, Caitlin Ryan, Aimee Fisher and Kayla Imrie have now achieved a top-ten world ranking. Footage posted to their Facebook page demonstrates how hard they have been training under coach Rene Olsen, and it shows in their much improved form. We look forward to seeing how far they can push it. Their race is due to start at 21.05 NZ time and will be live streamed here.
Unfortunately the men did not fare as well, with the K2 team of Zac Franich and Darryl Fitzgerald finishing seventh in their 1000m C final.
Sunday's Racing
Testing conditions in contributed to a shaky start for Lisa. However, her impressive back stoke had her powering through the field to finish almost half a boat length ahead of Poland's Marta Walczykiwicz and Teresa Portela of Spain.
Racing was slower than expected with competitors hampered by choppy water and a side breeze: Lisa's start was shaky and she looked to be struggling at first. Impressive pace by Marta Walczykiwicz of Poland and a strong start from Teresa Portela of Spain saw Lisa coming from behind to lead at the halfway mark, accelerating impressively towards the finish with final time of 40.060 seconds – a convincing 0.640sec and 1.188sec lead over the second and third paddlers respectively.
The kiwi K4 girls raced with heart but placed last in the Women's K4 500m A Final. The strong field was won by the Belarus women who fought off the incredibly close Hungarian and German teams to achieve a winning time of 1:33.953 seconds. The NZ girls were nearly 4 seconds off the pace, came very close to the French Team.
Although hoping for a top-eight place, the girls were elated to have qualified for the A Finals, especially after only nine months as a team. Their third place in the Semi-Finals ensured they had met the technical standard for the Olympics meaning that they are likely to compete at Rio 2016.
They have made strong improvements at every outing this year. We look forward to seeing how they perform at the Oceania Champs.
Racing Guide
Results of the racing from the Milan Canoe Sprint Champs Website
Milan Canoe Sprint Champs You Tube Channel for replays of the racing
Sky Sport Pop up Channel 058 also played the finals on Sunday night.
Planet Canoe You Tube Channel
Fridays Semifinals
Saturdays Semifinals
Saturday Finals
Sundays Finals
2015 Canoe World Sprint Champs racing times and results table
Scott Martlew, MK1 200, KL3, H2 L3, 2nd in 44.186 to semi
Scott Martlew, MK1 200, KL3 ,SF1-4, 3rd in 43.688 to B final
Lisa Carrington, WK1 500, H2 L5, 1st in 1.54.291 to Semi
Lisa Carrington, WK1 500, S 1-4, 1st in 1.49.407 to A Final
Marty McDowell, MK1 1000, H1 L8, 6th in 3.40.005 - out
Zac Franich/Darryl Fitzgerald, MK2 1000, H5 L2, 6th in 3.25.729 to Semi
Zac Franich/Darryl Fitzgerald, MK2 1000, S 1-4, 6th in 3.18.344 to C Final
Lisa Carrington, WK1 200, H1 L5, 1st in 40.330 to Semi
Jaimee Lovett/Caitlin Ryan/Aimee Fisher/Kayla Imrie, WK4 500, H2 L7, 2nd in 1.34.892 to Semi
Scott Martlew, MK1 200 KL3, B Final, 1st in 42.434
Lisa Carrington, WK1 500, A final, 1st in 1.49.398
Lisa Carrington, WK1 200, S 1-4, 1st in 39.925 to A Final
Jaimee Lovett/Caitlin Ryan/Aimee Fisher/Kayla Imrie, WK4 500, S2 L5, 3rd in 1.33.943 to A final
Zac Franich/Darryl Fitzgerald, MK2 1000, C final, 7th in 3:25.240
Lisa Carrington, WK1 200, A final, 1st in 40.060
Jaimee Lovett/Caitlin Ryan/Aimee Fisher/Kayla Imrie, WK4 500, A final, 9th in 1.37.698
The NZ Kayaking Team
Lisa Carrington
Lisa Carrington has won the gold medal of the Women's K1 500m and 200m, achieving her goal of a historic double victory.
"Lisa truly is worth her weight in gold, not just for the glittering titles she brings back to our shores but also the role modeling she provides," Canoe Racing NZ boss Mark Weatherall says. "She's such a focused, disciplined athlete and having her in a New Zealand team rubs off on the other athletes. You can see how important this is by the way the K4 team has lifted this year, while a number of our younger paddlers shone at the recent under-23 world championships. She's a benchmark for all paddlers to aspire to."
After an impeccable start to the racing year, including several Gold Medals at the European Champs, Lisa is the one to beat at any event. As the commentators say, it is not only her strength but her consistency that makes her probably the best paddler in the world today. We are so proud to see her qualify for Rio where she will again be racing her Nelo Cinco and using a Jantex Gamma Rio Paddle.
Lisa Carrington Facebook Page
Lisa Carrington Twitter
Lisa Carrington Instagram
Scott Martlew
Scott won the B Final of the K1 Mens 200m KL3 on Friday. In Wednesday's heats he finished third in the KL3 200m semifinal, behind Russia's Leonid Krylov (whose time of 40.168 sec was the fastest overall) and Ireland's Patrick O'Leary. Martlew's 43.688 sec effort improved on his 44.186 heat time, though not by enough. In the end he was just 0.45 seconds off making the A final and pushing for the top-six finish that would've opened up a spot in paracanoeing's Olympic debut in Rio de Janeiro.
"Still disappointed I missed the A final but happy I improved from my semi to the final. Thank you to everyone that helped make this trip possible." he said on his Facebook Page. It's not the end of Scott’s road to Rio – there are four spots up for grabs at the World Championships next year in Germany. Scott had been training hard this winter in frosty Christchurch conditions: fortunately he has acclimatised to the European summer by training in the 40ºC heat in the Czech Republic over the last few weeks. Scott will be racing the new Nelo Cinco Paracanoe and a Jantex Beta Rio paddle in the LTA Category. The Worlds are the first major outing for Nelo’s new Cinco Paracanoe. Nelo are hoping it will help set some new records during the paralympic competition, as the previous incarnation - the Nelo Viper Paracanoe – did when it was launched. We're big fans – read about Scott's inspirational journey here.
Scott Martlew Facebook Page
Scott Martlew Twitter
Scott Martlew Instagram
Marty McDowell
McDowell has been eliminated from the K1 1000m competition. He had the unluckiest race of the day on Thursday, drawing the fastest heat of the morning and finishing sixth to miss the semi-finals by one spot. His 3:40.005 time would've been comfortably enough to progress in four of the other six heats. When Marty smashed Silver Medalist Ben Fouhy by nearly five seconds at the Nationals this year, we had to take note of his amazing speed. He did well at the European Champs too. But what's most exciting about Marty's recent form is how quickly he is improving. Despite a disappointing result at the Worlds, he will still be gunning for a place on the Rio team at the Oceania Champs later in the year.
Marty McDowell Facebook Page
Womens K4 Team
The Women's K4 Team have placed ninth in the competition, and met the qualifying standard for the Olympics. If they are selected, it will be the first women K4 team to go to the Olympics. It's been 23 years since New Zealand last had an Olympic K4 boat, with Richard Boyle, Finn O'Connor, Stephen Richards, and Mark Scheib making the semifinals in Barcelona in 1992, after earlier men's K4 crews in 1984 and 1988.
The four team members Jaimee Lovett, Caitlin Reid, Aimee Fisher and Kayla Imrie, have been working well together and seen massive improvements under their coach Rene Olsen. Although they're a relatively inexperienced team, their confidence was boosted by good results at the World Cup in Europe earlier in the year, where members also raced in pairs in the K2 division. It will be great to see the K2 pairings from this team race in the Oceania qualifiers, if necessary. These ladies looked fast in their Nelo K4 Vanquish III kayak. Check out the training video at Lake Bled in Slovania, posted on their Facebook page.
NZ K4 Women's Team Facebook Page
Mens K2 Team
Zac Franich and Darryl Fitzgerald finished seventh in the Saturday's Mens K2 500m C final. They finished sixth in their K2 1000m semi-final, where the top 12 K2 crews were all within 3secs of each other, with Franich and Fitzgerald less than 10secs back after a 3:18.344 semi-final effort, which was a 7secs improvement on their heat time. Zac Franich and Darryl Fitzgerald have both fought hard to get to the Worlds – on and off the water.
Quick Links to some great information
Nelo NZ Facebook Page Paddling news curated by ipaddle from all around the web Nelo International Facebook Page Some great photos of the athletes and boats (from the people that look after them)
NZ Canoe Racing Website Check out the News and Events banner for the latest from inside the Kiwi Camp. NZ Canoe Racing Facebook Page Really good posts and links to other paddling stories in the media.
Nelo NZ website Take a closer look at the Nelo Cinco and other Nelo Boats used by the NZ Kayaking Team. ipaddle is the exclusive NZ distributor of Nelo Kayaks Jantex International Website Check out the paddles the team uses. ipaddle is the exclusive NZ Jantex distributor see Jantex paddles here
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With the sea coming and going relentlessly against rocks, pebbles and the granite fortresses of men, the coastal edge close up is a potent place for me.
On occasion I have placed small sculptures and carvings, drawings too, into the sea at this edge and photographed them. This quickly became part of an old myth - the birth of Venus - though perhaps only more flotsam and jetsam in there with the rest.
I lost two small carvings sucked away on an undercurrent - as if the sea thought this might be an interesting game to play - a ritual in the making, perhaps… This is how things begin with me - quietly and without any great intention or mystery, like something subversive has slipped in covertly through the back door. I was reminded too of how Braque would take his small paintings out into a field, place them in some ploughed furrow to see how they would hold up
A year in Venice
...This work is not in any way a naturalistic approach to the image, nor really expressionistic, but more an attempt to catch the poetic sense of form and surface that gives the city such poignancy. These are not 'views' of, but a re-making of the observed image, or a re-inventing via and and through the imagination. There is a simplicity and directness in this which gives the work a singular quality. Architectural features and the simple geometry of buildings are treated as if in some theatre of memory. Themes evolve into sequences that explore the mystery of the city's inner world - one can almost sense his daily pattern of work and how it moved on and changed through these subtle dialogues with the image. After all Venice is a theatre, a stage on which its history is played out at every turn. His small sculptured figures seem to be dancing on this stage... Ian James Martin's Gallery 2011
If you had to build a model of the unconscious it would probably look something like Venice - would probably have, need to be, a labyrinthine structure with plenty of dead ends and secret openings, with always fleeting glimpses of further intrigue and astonishment. Would be a mosaic of patterns promising insight, even salvation, breath-taking in their beauty, but always revealing yet another mystery. It would be made of many layers - a Babel of racial memories and denial. It would need to sparkle in the dark like a fairy tale. Should have red and gold banners skilfully flowing down from carved buildings. And every day, like a call to prayer across this structure, there would need to be, songs of death and glory and sexual adventure, ritually performed as incantations to all our desires... Finally it should appear like a grand raft loaded with plunder and treasure, cast free of its moorings and allowed to drift. All this should appear to be to be impossible and hopelessly unreal, a magician's play with belief.
Fragment from Venice notebook 2009
Four years ago John Trigg returned from Venice where he spent a year lost in Tintoretto and other classical masters, religious icons and architecture. Returning to his studio in Penzance, Trigg has transposed the essence and sensibilities of Venice, the iconography and dark corners where the sun has never shone, the softness of stone touched a thousand times and over, into a body of work drawn from the 'Seas Edge' seascapes, where the ocean appears as if cupped and proffered by the land, and portraits - a series of drawings and paintings of 'Tombstone Boys.'
Jenny Blyth - Art Jericho - 2014
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Home / Tag Archives: url
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Gab wants to add a comments section to everything on the internet – CNET
February 27, 2019 Killer Apps Headlines
Dissenter lets you comment on tweets, websites and anything else with a URL.
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JOHANNESBURG, October 18, 2018 /PRNewswire/ -- Sasol has published its production and sales performance metrics for the three months ended 30 September 2018 on the Company's website at http://www.sasol.com, under the Investor Centre section or via this URL:...
Zimmer and Apple launch clinical study covering up to 10K patients who get knee and hip replacements
Apple has made health — and helping people keep tabs on theirs — a cornerstone of how it is presenting the benefits of its newest Apple Watch, and today comes news of another way that this is taking shape. Zimmer Biomet , a world leader in developing the components and systems for joint replacements, says that it is working with Apple on a new clinical study focused on people who get knee and hip replacements. The trial will come in three stages, and within two years, Zimmer projects that there to be up to 10,000 people involved, Ted Spooner, Zimmer’s vice president of connected health, said in an interview. It will cover three aspects of patient care, he said: monitoring patients before and after operations using sensors on the Apple Watch and iPhone; providing education and information to patients to help improve their pre- and post-operation care; and providing a communications channel between doctors, caregivers and patients to ask questions, give answer and more, using Zimmer’s mymobility app. Institutions that will be participating include University of Utah Health; Rush University Medical Center; University of Pennsylvania Health System; Emory University Orthopaedics & Spine Hospital/Emory Healthcare; Hoag Orthopedic Institute in Southern California; Newton-Wellesley Hospital, member of Partners HealthCare founded by Massachusetts General Hospital and Brigham and Women’s Hospital; Centura Health, Porter Hospital – Colorado Joint Replacement (CJR); ROC Orthopedics, affiliated with Legacy Meridian Park Medical Center; OrthoBethesda; OrthoArizona; Midwest Center for Joint Replacement; Hartzband Center for Hip & Knee Replacement; New Mexico Orthopaedic Associates; The DeClaire LaMacchia Orthopaedic Institute, affiliated with Michigan Institute for Advanced Surgery; Joint Implant Surgeons; Orthopedic and Fracture Clinic; Panorama Orthopedic and Spine Center. The study — which for now will be US-only — comes after two years of Zimmer working with Apple behind the scenes, Spooner said, on not just making sure the parameters of what Zimmer hoped to achieve in a connected app would be possible, but also for Apple to understand what stakeholders in the health industry would want to see out of a health service built around a smartwatch and smartphone. Zimmer was a key target because today it accounts for one in every four knee replacements globally, and it has similarly strong market positions in hip, shoulder, foot, dental and spine products. A measure of where Apple is placing the importantance of this study is who they have commenting on its launch. “We believe one of the best ways to empower consumers is by giving them the ability to use their health and activity information to improve their own care,” said Jeff Williams, Chief Operating Officer, Apple, in a statement. “We are proud to enable knee and hip replacement patients to use their own data and share it with their doctors seamlessly, so that they can participate in their care and recovery in a way not previously possible through traditional in-person visits. This solution will connect consumers with their doctors continuously, before and after surgery.” Hip and knee replacements are the most common “replacement” procedures that take place, accounting for one million operations each year in the US, according to Deloitte, a figure that will grow to 3.5 million by 2035 as our population grows, stays alive for longer, and includes more people who were much more active in their earlier years in a wider upswing for fitness. You might assume that it would be an uphill challenge to sell the idea of connected health services to older people — who are the typical recipients of these operations — but Spooner said that the opposite is the case. “It turns out that the fastest adoption group for smartphones is 55-64 right now,” he said, saying that they are currently buying smartphones and other connected devices three times as fast as the next group down. Some of that of course might be because older people have been slower to adopt, but nevertheless, he points out, the stats “are really staggering, considering that other groups are at less than a two percent compound annual growth rate.” Smart watches, he said, have a similarly high growth rate among the elderly.
Amazon debuts a retail site for ‘Shark Tank’ products
Inventor Jamie Siminoff was rejected by the sharks on ABC’s “Shark Tank” in 2013 when trying to make a deal for his video doorbell startup. This year, Amazon bought his company , Ring, for a billion dollars. Now, Amazon is looking for another way to tap into breakout products from the popular TV show – by becoming an official retailer partner for “Shark Tank.” The newly announced deal allows Amazon to showcase past and future “Shark Tank” products on its website, and come with a $15,000 Amazon Web Services (AWS) credit for each eligible “Shark Tank” entrepreneur. The products will be available in a new Shark Tank Collection on Amazon Launchpad, its platform for hardware and physical goods startups, which first arrived in 2015 . The idea is to offer a dedicated place on Amazon where consumers can shop products from up-and-coming companies, like Bluesmart’s luggage, eero’s Home Wi-Fi system, Casper mattresses, and hundreds more. This new collection is not the first time Amazon has featured “Shark Tank” products on its site, however. Also in 2015, Amazon launched a new online store called Amazon Exclusives, which featured a variety of new brands, including products from “Shark Tank,” like Tower Paddle Boards, for example. At the time, the “Shark Tank” merchandise selection was limited, though. With today’s launch, that’s changing. Amazon says the new collection features over 70 products that successfully received funding from “Shark Tank” seasons 1 through 9, and new products from season 10 and beyond will be featured here in the future. The products available today include things like smart changing pad and scale Hatch Baby , coffee enhancer Third Wave Water , and storage bags from Stasher , among others. You can even sort and filter products by those that were funded by two or more sharks, or those with over $250,000 in funding. “For the first time ever, ‘Shark Tank’ has a store on Amazon.com dedicated to helping our entrepreneurs scale their businesses and highlight top products from the show,” said “Shark Tank” investor, Barbara Corcoran, in a statement. “We are excited for the Amazon Launchpad Shark Tank Collection to bring products from our entrepreneurs to retail for customers and fans of the series.” For Amazon, the deal isn’t just a way to redirect “Shark Tank”-related shopping searches to its site, following an airing of the TV show. It also gives Amazon a first-hand way of seeing which products are becoming viable consumer hits – something that could open the door for an acquisition or further deal-making at some later point, perhaps
Adobe launches new AR and drawing tools
At its Max conference in Los Angeles, Adobe today announced a number of new products in its Creative Cloud suite. Among those is Project Aero, a new tool that allows for building new AR experiences, and Project Gemini for painting and drawing on the iPad. The ‘Project’ moniker is Adobe’s way of signifying that these are still early-stage products and not quite ready for prime time yet. Over time, though, they typically become fully named parts of the Creative Cloud suite. The fact that Adobe is launching a tool for building AR experience doesn’t come as a major surprise. Adobe isn’t one to stand by as hype builds around a new technology (see: Adobe’s early support for VR). Project Aero, which integrates with both Adobe Dimension and Photoshop for creating importing assets, is now in private beta, with plans for a wider release in 2019. The other new tool is Project Gemini, which takes some of Adobe’s Photoshop technology, including its painting engine, to create a stand-alone drawing app for the iPad. The app also takes some cues from existing drawing tools from Adobe like Photoshop Sketch and Illustrator Draw. Indeed, it gets its time-lapse recording feature and support for Photoshop brushes from these — but in a new package that also includes selection and masking tools, grids, drawing guides and a mix of raster and vector drawing capabilities. One interesting note here is that Kyle T. Webster is behind this new project. Last year, Adobe bought Webster’s Photoshop brush tools almost exactly one year ago .
Vinli launches mobility data platform, signs partnership with ALD Automotive
Connected car startup Vinli aims to connect vehicles to the cloud and is today announcing a change in its business model as it partners with the largest fleet operator in Europe, ALD Automotive. Vinli launched in 2014 as a direct consumer company that allowed owners to add cloud services to automobiles. It was a clever concept, and when it launched four years ago, it was ahead of the curve. The company went on to raise to $6.5M through four rounds of funding, slowly evolving the product to meet the changing needs of the market. Today, the company is announcing a change in focus and will no longer sell products directly to consumers. The company founder and CEO Mark Haidar tells TechCrunch this is in response to the product’s evolution, which can now offer enterprises a platform for them to launch their own mobility applications directly to their users. Vinli is discontinuing the production of its hardware and will work with partners to offer the same services to consumers. To go along with this new business strategy, Vinli is launching a data platform that Haidar tells me can ingest data from any source and correlate it with machine learning and AI, allowing customers to develop predictive services for their products. Called Era, Vinli believes this will enable its customers to mine trends from data without the need of data scientists. Vinli signed a deal with ALD Automotive to add its connected services to its fleets of 1.6 million vehicles. In a press release, ALD Automotive says Vinli will enrich ALD’s “overall service offering and develop new value-added solutions to improve both driver experience and optimize overall Total Cost of Ownership for efficient fleet management.” “We believe that the automotive industry is evolving to become a service-based and subscription-driven industry,” said Mark Haidar, CEO of Vinli. “Connected cars and data are at the epicenter of this change. Collecting, analyzing, and discovering trends from ALD’s fleets will not only be transformative to the driver but to the industry as a whole” Terms of the partnership were not released. Connecting vehicles to the cloud has significant implications as car makers, insurers and consumers alike can gain deep insights into the habits of the driver and mechanics of the car throughout its life. Vinli seems well positioned to offer a platform to provide this data and today’s moves should help the company into the future
Adobe is bringing Photoshop CC to the iPad
It’s no secret that Adobe is currently in the process of modernizing its Creative Cloud apps and bringing them to every major platform. Today, the company is using its Max conference in Los Angeles today to officially announce Photoshop CC for the iPad . Sadly, you won’t be able to try it today, but come 2019, you’ll be able to retouch all of your images right on the iPad. And while it won’t feature ever feature of the desktop from the get-go, the company promises that it’ll add them over time. As with all of Adobe’s releases, Photoshop for iPad will play nicely with all other versions of Photoshop and sync all the changes you make to PSD files across devices. Unsurprisingly, the user experience has been rethought from the ground up and redesigned for touch. It’ll feature most of the standard Photoshop image editing tools and the layers panel. Of course, it’ll also support your digital stylus. Adobe says the iPad version shares the same code base as Photoshop for the desktop, “so there’s no compromises on power and performance or editing results.” For now, though, that’s pretty much all we know about Photoshop CC on the iPad. For more, we’ll have to wait until 2019. In a way though, that’s probably all you need to know. Adobe has long said that it wants to enable its users to do their work wherever they are. Early on, that meant lots of smaller specialized apps that synced with the larger Creative Cloud ecosystem, but now it looks as if the company is moving toward bringing full versions of its larger monoliths like Photoshop to mobile, too.
Celonis brings intelligent process automation software to cloud
Celonis has been helping companies analyze and improve their internal processes using machine learning. Today the company announced it was providing that same solution as a cloud service with a few nifty improvements you won’t find on prem. The new approach, called Celonis Intelligent Business Cloud, allows customers to analyze a workflow, find inefficiencies and offer improvements very quickly. Companies typically follow a workflow that has developed over time and very rarely think about why it developed the way it did, or how to fix it. If they do, it usually involves bringing in consultants to help. Celonis puts software and machine learning to bear on the problem. Co-founder and CEO Alexander Rinke says that his company deals with massive volumes of data and moving all of that to the cloud makes sense. “With Intelligent Business Cloud, we will unlock that on prem data, bring it to the cloud in a very efficient infrastructure and provide much more value on top of it,” he told TechCrunch. The idea is to speed up the whole ingestion process, allowing a company to see the inefficiencies in their business processes very quickly. Rinke says it starts with ingesting data from sources such as Salesforce or SAP and then creating a visual view of the process flow. There may be hundreds of variants from the main process workflow, but you can see which ones would give you the most value to change, based on the number of times the variation occurs. Screenshot: Celonis By packaging the Celonis tools as a cloud service, they are reducing the complexity of running and managing it. They are also introducing an app store with over 300 pre-packaged options for popular products like Salesforce and ServiceNow and popular process like order to cash.
Saudi ally calls for Uber boycott over response to Khashoggi’s vanishing
Uber is facing calls for a boycott of its app in the Persian Gulf, a region that has poured billions of dollars of investment into the company’s ride-hailing business in recent years: Directly via Saudi Arabia’s Public Investment Fund (PIF) and indirectly because the Saudis are major investors in Softbank’s Vision Fund vehicle , which is another big Uber investor . The regional calls to boycott Uber were stoked yesterday by Saudi ally, Bahrain, whose foreign minister retweeted hashtags calling for a boycott of the company, according to reports by Bloomberg and Reuters . An Uber spokesperson declined to comment when reached for a response. No place for you in Saudi Arabia #DeletingUber pic.twitter.com/hYLXXEKFQI — عبدالله الشهراني (@abdullh2223) October 14, 2018 A few boycott calls circulating on Twitter urge app users to switch to Uber ride-hailing rival, Careem , though it’s unclear whether Uber alternatives are seeing any local uplift as yet. Anger at Uber has been sparked by the reaction of CEO Dara Khosrowshahi to the disappearance of Saudi journalist, Jamal Khashoggi , a U.S. resident, who has not been seen since entering the Saudi consulate in Istanbul on October 2 for a pre-arranged appointment to obtain documentation for his forthcoming marriage to a Turkish citizen. Newspaper reports have suggested Khashoggi was killed inside the embassy by a Saudi hit squad that traveled to Turkey for the purpose of carrying out the murder. As a Saudi ex-pat the journalist had written critically of the crown prince’s regime. And while independent CCTV footage shows Khashoggi entering the embassy but there is no proof to show he ever left. Although the Saudis have denied any wrongdoing, and claimed their citizens were just visiting Turkey as tourists. Following growing alarm over Khashoggi’s disappearance, Uber’s CEO was among several business leaders to announce they were pulling out of an investment conference due to take place in the Saudi capital later this month. “I’m very troubled by the reports to date about Jamal Khashoggi. We are following the situation closely, and unless a substantially different set of facts emerges, I won’t be attending the FII conference in Riyadh,” said Khosrowshahi in a statement last week. Uber confirmed to TechCrunch today that Khosrowshahi will not be attending the Future Investment Initiative conference — a conference’ s hosted by Saudi’s crown prince, Mohammad bin Salman bin Abdulaziz Al-Saud, aka MBS, who is also chairman of the PIF; a key Uber investor, which has a member sitting on Uber’s board . Those links underline quite how complicated managing this particular piece of legacy baggage is for Khosrowshahi — who, as Uber’s new broom, has made it his stated mission to chart a new course by ‘ doing the right thing. Period ‘. Yet when Uber accepted $3.5BN from the Saudi PIF two years ago ‘doing the right thing’ meant just one thing: Growing Uber, with few if any other considerations on the table for then CEO and founder Travis Kalanick
Truphone, an eSIM mobile carrier that works with Apple, raises another $71M, now valued at $507M
Truphone — a UK startup that provides global mobile voice and data services by way of an eSIM model for phones, tablets and IoT devices — said that it has raised another £18 million ($23.7 million) in funding; additionally securing £36 million ($47 million) more “on a conditional basis” to expand its business after signing “a number of high-value deals.” It doesn’t specify which deals these are, but Truphone was an early partner of Apple’s to provide eSIM-based connectivity to the iPad; and it will also be offering a service for new iPhone XS and XR models , taking advantage of the dual SIM capability. Truphone says that strategic partners of the company include Apple (“which chose Truphone as the only carrier to offer global data, voice and text plans on the iPad and iPhone digital eSIM”); Synopsys, which has integrated Truphone’s eSIM technology into its chipset designs; and Workz Group, a SIM manufacturer, which has a license from Truphone for its GSMA-accredited remote SIM provisioning platform and SIM operating system. The company said that this funding, which was made by way of a rights issue, values Truphone at £386 million ($507 million at today’s rates) post-money. Truphone told TechCrunch that the funding came from Vollin Holdings and Minden Worldwide — two investment firms with ties to Roman Abramovich, the Russian oligarch who also owns the Chelsea football club, among other things — along with unspecified minority shareholders. Collectively, Abramovich-connected entities control more than 80 percent of the company. We have asked the company for more detail on what the conditions are for the additional £36 million in funding to be released and all it is willing to say is that “it’s KPI-driven and related to the speed of growth in the business.” For some context, Truphone most recently raised money almost exactly a year ago, when it picked up £255 million also by way of a rights issue, and also from the same two big investors. The large amount that time was partly being raised to retire debt. That deal was done at a valuation of £370 million ($491 million at the time of the deal). Going just on sterling values, this is a slight down-round. Truphone, however, says that business is strong right now: “The appetite for our technology has been enormous and we are thrilled that our investors have given us the opportunity to accelerate and scale these groundbreaking products to market,” said Ralph Steffens, CEO, Truphone, in a statement. “We recognised early on that the more integrated the supply chain, the smoother the customer experience. That recognition paid off—not just for our customers, but for our business. Because we have this capability, we can move at a speed and proficiency that has never before seen in our industry. This investment is particularly important because it is testament not just to our investors’ confidence in our ambitions, but pride in our accomplishments and enthusiasm to see more of what we can do.” Truphone is one of a handful of providers that is working with Apple to provide plans for the digital eSIM by way of the MyTruphone app. Essentially this will give users an option for international data plans while travelling — Truphone’s network covers 80 countries — without having to swap out the SIMs for their home netw orks
It’s official: London-based Stride.VC raises £50M seed fund
Stride.VC , the new VC fund from Fred Destin, formerly a partner at Accel, and Harry Stebbings, producer of the “The Twenty Minute VC” podcast and ex-Entrepreneur-in-Residence at Atomico, is being officially unveiled today, confirming most of the details of my earlier report . The fund has closed at just over its £50 million target and will be used to do seed investments exclusively in U.K. startups (at least for now). The team has been bolstered, too, with Arj Soysa, ex-Atomico and most recently head of finance for LGT Impact, joining as operating partner. The firm also disclosed its first investment earlier this month, backing healthcare messaging app Forward Health . In a call with Destin last week and followed up over subsequent emails with the pair, I got further details on Stride.VC’s LPs and how Destin and Stebbings plan to approach seed investing. Kicking off, I asked if perhaps there was already enough money in the U.K. (and elsewhere in Europe) chasing seed-stage startups. “We don’t think there is too much seed money at work in Europe,” says Destin. “We think tech startups are impacting more and more industries and sectors so the importance and impact of great founders is growing.
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AvidXchange raises $260 million to support continued growth
Healthcare Cloud Computing World Market Analyses; 2014-2019 & 2020-2026
Amazon, Disney, and EA Veteran Roie Chizik Named Machine Zone’s Chief Financial Officer
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Torquay, Meadfoot Beach, Devon © Tony Atkin
Countryside Organisations
Convention on Biological Diversity promotes nature and human well-being.
Biodiversity and climate change are closely linked, and each impacts upon the other: biodiversity is threatened by human-induced climate change, but biodiversity resources can reduce the impacts of climate change on population and ecosystems.
Dept for Environment, Food & Rural Affairs website provides a series of guidance pages on key issues concerning environmental and land management.
The Agency is the leading public body for protecting and improving the environment in England and Wales - to make sure that air, land and water are looked after by everyone in today's society, so that tomorrow's generations inherit a cleaner, healthier world.
Friends of the Earth campaigns for solutions to environmental problems.
Greenpeace is an independent global campaigning organisation that acts to change attitudes and behaviour, to protect and conserve the environment and to promote peace.
Natural England works for people, places and nature to conserve and enhance biodiversity, landscapes and wildlife in rural, urban, coastal and marine areas.
Natural Environment Research Council
Click for NERC website
Conservation organization working around the world to protect ecologically important lands and waters.
Recycling is an excellent way of saving energy and conserving the environment - this site is full of useful information and resources.
UK's leading environmental charity promoting sustainable, organic farming and championing human health.
United Nations Environment Programme. Mission Statement - To provide leadership and encourage partnership in caring for the environment by inspiring, informing, and enabling nations and peoples to improve their quality of life without compromising that of future generations.
Useful information about the sources of water pollution and how they can be treated.
Water UK
Water UK say their longterm vision is 'for a sustainable water industry that will:
• Protect and promote public health
• Provide a high quality, reliable and value-for-money service
• Respond to climate change
• Reduce our impacts on the environment
World Land Trust
The World Land Trust (WLT) is an international conservation organisation that takes direct action to save rainforest and other biologically important lands — buying it, acre by acre.
Campaign for Real Ale (CAMRA)
CAMRA was created in 1971 by four men from the north-west who were appalled by the domination of the UK beer market by a handful of companies pushing products of low flavour and overall quality onto the consumer.
Click for pubs and hotel within TQ6 serving real ales
Countryside Alliance
Click for Countryside Alliance Website
Countryside Council for Wales
Click for CCW website
Click for Natural England website
Click for National Farmers Union website
Ramblers Association
Click for Ramblers Association website
Click for National Trust Website
Click for the Woodland Trust website
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Jeep Compass diesel-automatic launched in India, priced from INR 22 lakh
Prashant Singh | 14/01/2020 - 16:47
FCA has launched the Jeep Compass diesel-automatic in India, with prices starting at INR 21.96 lakh*. Bookings and test drives have commenced at all the 80 FCA showrooms in India.
2021 Jeep Compass (facelift) makes spy photo debut - First look at new exterior & interior
Sagar Parikh | 10/01/2020 - 04:15
The 2021 Jeep Compass has been spied for the first time. Reports suggest that the facelifted Jeep Compass will be launched in India in the second half of the year.
New details about Jeep Compass diesel-automatic emerge ahead of impending launch - Report
A recent report had said that the Jeep Compass diesel-automatic that will be launched in India this month will be available in the Limited Plus grade. According to a new report, it will be sold in..
Jeep Compass diesel-automatic to be launched this month, priced at ~INR 25 lakh - Report
Launched in July 2017, the Jeep Compass received a diesel-AT combo with the off-road-oriented Trailhawk variant only in June 2019. Because of the Trailhawk variant's steep price of INR 26.80 lakh*,..
BS-VI Jeep Compass petrol with more powerful engine spied
The Jeep Compass petrol has been spotted with a more powerful, 170 PS 1.4L MultiAir engine (according to the document sheet glued to its rear-glass). This engine is an upgraded, BS-VI version of the..
7-seat Jeep SUV for India spied for the first time, won't be just a longer Jeep Compass
FCA's 7-seat Jeep SUV (codename: Jeep 598) that has been officially confirmed to be launched in India has been spied for the first time, courtesy Auto Esporte. According to the source publication, the..
7-seat Jeep Compass - Fresh details emerge from Brazil
It is no news that Jeep is working on a longer/7-seat version of the Compass a.k.a 'Grand Compass' which is set to debut in 2021. Now, newer details have emerged from Brazil, thanks to..
Jeep Compass Available With Discounts Of Up To INR 1.6 lakh
Jeep dealers in India are offering huge discounts on select variants of the Compass for the month of November 2019. The most affordable model in the company's local lineup is currently being offered..
Facelifted Jeep Compass prioritised over 7-seat Jeep Compass - Report
The 7-seat Jeep Compass (codename: Low-D) was previously said to be launched in 2020. According to new a report from Autocar India, its launch has been postponed to 2021 as FCA wishes to focus on the..
Top 5 Jeep Compass rivals we wish were sold in India: From Kia Sportage to Toyota RAV4
jeogeorge | 26/08/2019 - 12:02
The Jeep Compass has highly popularised the C-SUV segment in India. It has motivated many automakers to launch a C-SUV in the country or localise their C-SUV in the future for competitive pricing...
Regular Jeep Compass to gain diesel-AT combo before Diwali - Report
Nearly two years after the Jeep Compass was launched in India, a diesel-AT combo was introduced, in June this year. However, it's currently exclusive to the SUV's off-road-oriented Trailhawk variant,..
Jeep Grand Compass (7-seat Jeep Compass) - IAB Rendering
FCA had confirmed the launch of a three-row Jeep SUV in India last year. This model will be nothing but a 7-seat version of the Jeep Compass. IAB's digital artist Shoeb Kalania has come up with a..
7-seat Jeep Compass and Jeep small SUV projects "progressing very well"
The Jeep Compass is FCA India's best-selling model in right now and moving forward, it wants to grow its SUV sales to a much higher level. The company has lined up several new Jeep launches for the..
7-seat Jeep Compass (Jeep Grand Compass) to be launched in India in 2020 - Report
Last year, FCA had confirmed that it will launch a three-row Jeep SUV in India by 2022, and it was speculated that this model will be a 7-seat version of the Jeep Compass. According to a new report..
Jeep Compass Trailhawk launched in India at INR 26.8 lakh
It was only a few days back when we test drove the Jeep Compass Trailhawk and now the same has been launched in India at INR 26.8 lakh (ex-showroom, pan-India). At this price point, it costs about INR..
Jeep Compass Trailhawk pre-bookings officially open in India
Jeep India today started officially accepted pre-bookings for the Compass Trailhawk for a token amount of INR 50,000, which is fully refundable. The pre-booking can be made at any of the 82 FCA..
Jeep Compass Trailhawk - First Drive Review
Yatharth Chauhan | 10/06/2019 - 10:30
What is it? The Jeep Compass Trailhawk is the more off-road-biased version of its regular iteration. The new model features a host of styling upgrades, with some of them even having a functional..
Jeep Compass Trailhawk - In 15 Live Images
Jeep is all set to launch the Compass Trailhawk in India by next month. We were invited for a first-hand experience of the upcoming 'Trail Rated' SUV, and here are some live images straight from the..
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Simplify NYS-DFS Information Security Compliance
The New York Department of Financial Services (DFS) cyber security law (NYCRR 500 Cyber Insurance Requirements for Financial Services Companies) sets forth a new regulatory framework that requires all financial institutions doing business in New York to adopt a formal and robust information security program. NYS-DFS sets a new precedent for state-level cyber security laws: It requires senior management to formally attest to the effectiveness of the information security program.
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Information Security Policies Made Easy provides complete security policy coverage for key information security and data privacy elements of NYS-DFS. Save time and money implementing policies by customizing our library of over 38 expert-written information security policies.
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Use ComplianceShield to help automate every aspect of an Information Security and Data Privacy Program that addresses NYS-DFS. Use our easy-to-use software tool to define, deliver and demonstrate a cyber security program. IT security compliance does not have to be difficult and expensive.
Information Security Policies and NYS-DFS
NYS-DFS specifically requires a set of written information security policies to support cyber risk management.
Section 500.03 Cybersecurity Policy.
Each Covered Entity shall implement and maintain a written policy or policies, approved by a Senior Officer or the Covered Entity’s board […] setting forth the Covered Entity’s policies and procedures for the protection of its Information Systems and Nonpublic Information stored on those Information Systems.
Section 500.03 goes on to list specific policy documents: (* All of which are included within our Common Policy Library)
(a) information security; *
(b) data governance and classification; *
(c) asset inventory and device management; (d) access controls and identity management; *
(e) business continuity and disaster recovery planning and resources; *
(f) systems operations and availability concerns; *
(g) systems and network security; *
(h) systems and network monitoring; *
(i) systems and application development and quality assurance; *
(j) physical security and environmental controls; *
(k) customer data privacy; *
(l) vendor and Third Party Service Provider management; (m) risk assessment; and *
(n) incident response. *
Enable Management Accountability
NYS-DFS is unique in that it requires senior management to officially attest to the effectiveness of the information security program.
Section 500.17 Notices to Superintendent.
(b) Annually each Covered Entity shall submit to the superintendent a written statement covering the prior calendar year. This statement shall be submitted by February 15 in such form set forth as Appendix A, certifying that the Covered Entity is in compliance with the requirements set forth in this Part.
Our ComplianceShield solution enables your organization to quickly establish a baseline of cyber security controls that address all elements of NYS-DFS. Once your program is established, using ComplianceShield to track accountability, compliance status and evidence.
Contact us today for a Free 30 Minute Consultation on how your organization can streamline and demonstrate NYS-DFS compliance.
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Home Politics & Government Mueller Report Finds No Russia Conspiracy, But Obstruction Of Justice Is A Murkier Question
Mueller Report Finds No Russia Conspiracy, But Obstruction Of Justice Is A Murkier Question
March 25, 2019 In Homeland Security Staff
Denver Officials Won't Hand Over Information Sought By ICE
Russias Foreign Minister Slams 'Aggressive' US Policies
A Brief 100-Year History Of Iran-West Relationships
U.S. And Iraq Reportedly Restart ISIS Counterterrorism Efforts
Russia's Assassination Campaign Continues Against Dissent
Why the U.S. Will Not Re-Institute the Military Draft
Facial-Recognition Scanners Are Coming To Philadelphia's Airport Starting Tuesday
US Defense Department Awards C3.ai $95M Contract Vehicle to Improve Aircraft Readiness Using AI
Ex-Trump Aide Michael Flynn Seeks To Withdraw Guilty Plea
By Steve Denning
Attorney General William P. Barr has delivered a letter to Congress summarizing the conclusions of the special counsel Mueller’s two-year investigation into Russian interference in the 2016 presidential election.
Russian Conspiracies To Influence The Election
According to Barr, persons associated with the Russian Federation did indeed conspire to influence the 2016 U.S. presidential election.
Russian President Vladimir Putin (Alexander Nemenov/Pool Photo via AP)
According to Barr, Mueller’s report states that “The investigation did not establish that members of the Trump campaign conspired or coordinated with the Russian government in its election interference activities.”
The finding is striking given the extensive public record, including material included in pleadings from the special counsel, that there is prima facie evidence of collaboration by President Trump and his inner circle with the Russians, as outlined in my December article here.
If Barr’s quote from the Mueller report is accurate, it would appear that Mueller’s team was not able to prove criminal conspiracy beyond a reasonable doubt, despite the fact that Trump campaign officials, including his son Don Jr, were aware of the Russian involvement and encouraged them. Trump himself publicly urged Russia to hack Clinton’s emails — on the very day Russian hackers tried to breach her emails for the first time.
The Trump family (AP Photo/Andrew Harnik)
The finding is also extraordinary, given that it is not necessary in the law of criminal conspiracy to prove that all participants knew all the details of the conspiracy or that they knew all the other participants. Nor is it even necessary that the conspiracy is implemented. Participation in an illegal agreement is enough by itself to constitute a crime. It remains to be seen what specific evidence and reasoning led Mueller to his finding.
We do not know from Barr’s letter whether the Mueller report dealt with other issues, such as Trump’s secret pursuit of a lucrative business deal while he was campaigning to be president, his continuing lies about the deal while he was president, and the risk of the U.S. Presidency having become a potential victim of blackmail (aka kompromat) at the hands of the Russian Federation.
No Exoneration Of Trump For Obstruction Of Justice
The appointment of special counsel Mueller was prompted by possible concerns of Trump obstructing justice, following the firing of FBI director, James Comey. Contrary to President Trump’s claim this afternoon that the Mueller report “totally exonerates” him of obstruction of justice, the Mueller report states that “while this report does not conclude that the President committed a crime, it also does not exonerate him.”
The failure to exonerate Trump is unsurprising, given the many examples of public conduct by Trump that seemingly indicate a systematic and unprecedented effort to obstruct justice.
According to Barr’s letter, the Mueller report “does not draw a conclusion—one way or the other—as to whether the examined conduct constituted obstruction.” According to Barr’s letter, the special counsel saw “’difficult issues’ of law and fact,” without specifying what they were.
Robert Mueller (AP Foto/Cliff Owen)
Barr’s letter nevertheless announces that he and Deputy Attorney General Rod Rosenstein have now concluded that the evidence is not sufficient to establish that the president committed an obstruction-of-justice offense. The letter gives weight to the fact that the Mueller report did not find that the president was involved in a criminal conspiracy with Russia, although it acknowledges that this is “not determinative.” It concludes summarily that the evidence—still unspecified—does not prove obstruction beyond a reasonable doubt.
We do not yet know whether the Mueller report refers to the many other investigations of Trump and his associates now under way at both the federal and state level.
House Judiciary Committee Chairman Jerrold Nadler (AP Photo/J. Scott Applewhite)
We do know that the Democratic Congress will not accept Barr’s summary letter as conclusive. The New York Times has reported that “Representative Jerrold Nadler of New York, the chairman of the House Judiciary Committee, said on Twitter that he plans to call Mr. Barr to testify about what he said were ‘very concerning discrepancies and final decision making at the Justice Department,’ seemingly referring to the attorney general’s conclusion that the president did not obstruct justice.”
“No one wants a president to be guilty of obstruction of justice,” writes Neal K. Katyal tonight in the New York Times. “The only thing worse than that is a guilty president who goes without punishment.”
As predicted in this piece of mine and this one by Katyal, it looks as though the “Mueller report will mark the end of the beginning, not the beginning of the end.”
And read also:
Mueller Exposes Putin’s Hold Over Trump
What The Mueller Report Will Say
Why The Trump Organization Now Risks Being Charged As A Criminal Enterprise
This article was written by Steve Denning from Forbes and was legally licensed through the NewsCred publisher network. Please direct all licensing questions to legal@newscred.com.
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Ink Heist
Genre fiction essays, reviews, and features on crime, horror, and SF
Ink Heist – A Podcast
Giveaway: Multiple Copies of Lullabies for Suffering!
Episode 2.02 – A Dark Night of the Soul with Samantha Kolesnik
Rich Duncan’s Favorites of 2019
Fiction: Keith Rosson “Their Souls Climb the Room”
Episode 2.01 – The Abyss Screams Back
UNWRAPPED #6 – An Interview With Leanna Renee Hieber
By Shane Keene on October 25, 2019 • ( Leave a comment )
Today I speak with Leanna Renee Hieber, actress, playwright and the author of The Spectral City about her work, mummies and monsters, and her short story “The Mummy of Rue de la Croix” from the Spirits Unwrapped anthology out now from Lethe Press.
Daniel Braum: Can you please tell us about your writing and your body of work. Please feel free to include any story links. Is there one story that you feel is a good introduction to readers who might not have yet read your work?
Leanna Renee Hieber: Everything I write centers ghosts and 19th century Spiritualism and the mediums and Sensitives within it, whether legitimate or fraudulent. So my story in Spirits Unwrapped is very on-brand. I love the greyscale area of spirit and skeptic, gifted or grifter, does one ever know? Most of my stories feature friendly ghosts trying to help the living and I’d like to think I’m presenting a different kind of ghost story in my work, one with a lot of heart and literal soul. My latest Spectral City series has captured my heart entirely; a journey I’d love everyone to join me on. The Spectral City, published with Kensington Books, follows a gifted young medium whose legitimate psychic talents has led to the establishment of The Ghost Precinct, a quiet department unveiled in 1899 New York City that works alongside the NYPD, whether they like it or not. Eve Whitby, her talented girl-gang of fellow psychics, her favorite friendly ghosts and one dashing Detective, Jacob Horowitz, make up the “personable cast and snappy prose” and “the diverse, lived-in world” (Publisher’s Weekly) of The Spectral City. Barnes & Noble: http://tinyurl.com/spectralbn IndieBound: http://tinyurl.com/spectralib AudioBook via Tantor: http://tinyurl.com/spectralaud Amazon/Audible: http://tinyurl.com/spectralaz
DB: How does your story “The Mummy of Rue de la Croix” fit with and relate to some of your other stories?
LRH: While no direct characters cross over into this story as they do in nearly all my other work, the themes of 19th century theatricality, stage work, mediumship and unknown phenomena is core to so much of my work. The fact that the “horror” turns out to be an unexpected something leading to camaraderie rather than a terrifying reveal is very much my style. I tend to work with friendly ghosts and ghouls. But that doesn’t mean there’s not startle, shock, suspense and uncanny shivers when engaging with my stories. I hope you can shudder and smile simultaneously.
DB: What aspect of mummy “lore” do you find the most appealing or most revolting?
LRH: I simply find the whole ritual and process of mummification fascinating. Utterly compelling. But here, I wanted to present a genre twist and honor one of my favorite monster stories, The Phantom of the Opera, at the same time. I love genre-blending with consistent call-outs to 19th century Gothic fiction.
DB: Setting plays a big part in your work. How did you decide on and work with the setting in “The Mummy of Rue de la Croix”?
LRH: I do a lot of passionate, irreverent lectures on Gothic fiction for conventions and institutions around the country. One of the elements I most love about Gothic storytelling, in addition to the close psychological focus and a constant feeling of dread, is the idea of ‘setting as character’. In “The Mummy of Rue de la Croix” my characters are informed by and are literally framed by the stage and theatre they work and live in. It is their whole world; their only safe haven. I loved taking you into their shadows as they try to figure out the mystery of their ‘special guest star’ who might just threaten everything.
DB: How does your work in the guide industry inform your fiction? What is the best part about the specialized tours that you direct?
LRH: I’m a very visual and tactile writer. I need to walk the paths my characters walk so I always go to the places I’ve set my work in. The reason why I became a tour guide was to learn more about the city’s history for the purposes of my books, it’s such an entwined calling. I love playing with theme and narrative, and I keep honing those aspects in my tours as I continue to hone my craft in my writing. The best part of my tours is sharing the incredible stories of New York History in a tactile way, standing before great historic structures both grand and mundane, especially when their drama is heightened by ghost stories and uncanny tales. I think the merging of history with the fantastic that craft in every tour is why reviewers call my books “lived-in” and immersive; because I really try to walk you, the reader, through my world in a way I hope you can simply escape into.
DB: Can you tell us about your newest work “A Sanctuary of Spirits”? And what are you working on now?
LRH: A SANCTUARY OF SPIRITS continues the unfolding mystery at the heart of Eve Whitby and her Ghost Precinct’s case; an interconnected horror of missing body parts, ghosts killed a second time, a charismatic magician, an unsettling mortician and a rich, powerful family with insidious secrets. It releases Nov. 12 in digital and paperback. Many reviewers have jumped in on this book without having read book 1, THE SPECTRAL CITY, and found their way just fine, it’s always up to reader preference. I’ve just finished working on the third book in the series, A SUMMONING OF SOULS, releasing next summer! Some of my favorite characters of all time. And as a character-driven novelist, this is particularly meaningful.
DB: Is there one “monster” that intrigues you that you would like to write about?
LRH: Much like I’ve done in an homage to classic works like The Picture of Dorian Gray in my Magic Most Foul saga beginning with Darker Still, I’d like to continue exploring all facets of ghost lore, Gothic themes and classic stories reimagined. I don’t think there’s any monster I wouldn’t like toying with, but ghosts really are my greatest loves and constant haunts so I’m happy floating along with them for as long as they’ll have me. Blessings and Happy Haunting!
Buy A Sanctuary of Spirits
Buy Spirits Unwrapped
LEANNA RENEE HIEBER is an actress, playwright and the author of thirteen Gothic, Gaslamp Fantasy novels for adults and teens for Tor and Kensington Books such as the Strangely Beautiful saga, the Magic Most Foul trilogy, the Eterna Files trilogy and The Spectral City series. Her fiction career began with her futuristic paranormal novella Dark Nest, which won the 2009 Prism Award for best novella, given by the Futuristic, Fantasy and Paranormal chapter of RWA. The Spectral City, Leanna’s new ghost-filled series set in 1899 NYC with Kensington Books, has been a bestseller across several genres and platforms. Her short fiction has appeared in numerous notable anthologies and her books have been translated into many languages. She has been a featured guest, guest of honor, panelist, performer and lecturer at countless conventions and writers’ organizations around the country. For more information, as well as writers’ tips and resources, visit http://leannareneehieber.com
DANIEL BRAUM is the author of the short story collections The Night Marchers and Other Strange Tales (Cemetery Dance), The Wish Mechanics: Stories of the Strange and Fantastic (Independent Legions 2017) and Yeti Tiger Dragon (Dim Shores 2016). His third collection, Underworld Dreams is forthcoming from Lethe Press in 2020. The Serpent’s Shadow, his first novel, was released from Cemetery Dance eBooks in July 2019. He is the editor of the Spirits Unwrapped anthology from Lethe Press and the host and founder of the Night Time Logic reading series in New York City which can also be heard on the Ink Heist podcast. He can be found at https://bloodandstardust.wordpress.com, www.facebook.com/DanielBraumFiction, and @danielbraum
SPIRITS UNWRAPPED can be ordered by your favorite local bookseller and also at Amazon, Barnes and Noble, and direct from the publisher.
https://www.barnesandnoble.com/w/spirits-unwrapped-daniel-braum/1133761071?ean=9781590216958
https://www.amazon.com/Spirits-Unwrapped-Daniel-Braum/dp/1590216954/ref=sr_1_1?keywords=spirits+unwrapped&qid=1571457869&sr=8-1
Categories: Features, Interviews
Tagged as: Features, Horror, Interview, MainFeature
UNWRAPPED #7 – An Interview with David Wellington
UNWRAPPED #5 an Interview With Rudi Dornemann
Episode 2.02 - A Dark Night of the Soul with Samantha Kolesnik
This week is a special one as we are joined by our new co-host, Laurel Hightower! We're excited to have Laurel join the Ink Heist podcast and she'll be joining us when she can in the future. This week, we sit down with author Samantha Kolesnik. Samantha's debut novel, True Crime, comes out tomorrow through Grindhouse Press and it's one yo […]
A Few Good Friends
While we stand behind our contributors 100%, their views do not necessarily reflect those of us at Ink Heist and, except editing for clarity and grammar, are printed verbatim as they were provided to us. We are committed to journalistic integrity and objectivity and to that end, allow our contributors to express their views unfettered and uncensored. If you take issue with something we publish, you are always welcome to rebut or to take it up with the author.
Click here to email Ink Heist.
Top categories: Features Cover Reveal
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Govt Constitutes Panel To Suggest Measures To Augment GST Revenue
On October 10, 2019 by Press Trust of India
Representational Pic
NEW DELHI – With the Goods and Services Tax (GST) collections dropping sharply to a 19-month low in September, the government has constituted a committee of officers to suggest measures to augment collections, expand the tax base and check evasion.
The panel comprising of state-level GST commissioners and centre government officials has been asked to suggest urgent measures to arrest the fall in tax revenues and suggest steps to be taken to improve revenue collection.
“The committee should consider a wide range of reforms so that a comprehensive list of suggestions may emerge,” an official order said.
It has been asked to consider a wide range of reforms so that a comprehensive list of suggestions may emerge. The panel has been asked to look into “systemic changes in GST including checks and balances to prevent misuse.” Also, it has been tasked to suggest measures to improve voluntary compliance as well as policy measures and changes in law needed.
Its key mandate is to suggest “measures for expansion of tax base” and make recommendations on “improved compliance monitoring and anti-evasion measures using better data analytics,” the order said.
GST collections dropped sharply to a 19-month low of Rs 91,916 crore in September, mirroring a widening slowdown in the economy triggered by shrinking consumer demand. This was the second straight month of decline in GST collections, which from July 1, 2017, amalgamated 17 different central and state levies, including excise duty, service tax and VAT.
The fall in tax collections is seen as a reflection of economic activity and a decline in collections indicated a downturn.
India’s GDP growth slowed to more than six-year low of 5 per cent in April-June, prompting the government to take an array of steps to boost the economy, including the steepest cut in corporate tax rate which would cost Rs 1.45 lakh crore.
The panel constituted on Thursday comprises state GST commissioners of Maharashtra, Tamil Nadu, Uttar Pradesh, West Bengal and Punjab besides central government officials including Principal Commissioner of GST and Joint Secretary (Revenue).
States have been asked to give suggestions in writing as well as join the panel.
“The Committee may co-opt or seek assistance from such officers from Centre/State as may be deemed necessary,” the order said.
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Reclaiming Pak Kashmir: MOS Defence Backs Army Chief’s Statement
Ladakh MP Blames Undefined LAC For Frequent Border Row With China
US Lawmakers Express Concern Over Human Rights Situation In Kashmir
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DDEX Knowledge Base
DDEX Home page
Release and Resource Metadata
Original Release Date, Release Date and other Dates
changes.mady.by.user DDEX Secretariat
Next Change: Difference between versions 4 and 5
The original Release Date is what enables a DSP to appropriately catalogue a track or album and put them into chronological order in which they were released. The following dates can be communicated:
to be added into Release and Resource Metadata
For a Release
ReleaseDate – the date where the Release at hand has first been (or will be) been made available to the public in its current form, whether for physical or electronic/online distribution.
For the Beatles' "White Album" this would be "1968-11-22" (or "1968" if less precision is required).
Note: This is not the date from when on the DSP is allowed to make the Release available to consumers; that date is part of the Deal section of the NewReleaseMessage.
OriginalReleaseDate – the date on which the collection of tracks for the Release (e.g. the equivalent physical album on vinyl) was or will be first made available for Usage.
In most cases this is the same as the ReleaseDate and thus does not need to be replaces. However, if the an album is re-mastered then the ReleaseDate of the re-mastered album would differ from the OriginalReleaseDate of the original album.
The Beatles' "White Album" was a re-released on white vinyl in 1978; to accompany that Release with dates, one could set the ReleaseDateOriginalReleaseDate to 1968 and the ReleaseDate to 1978.
OriginalDigitalReleaseDate - the date on which the Release was or will be first made available in electronic/online format.
For the Beatles' "White Album" this would be "2010" (the year in which the Beatles were available through an on-line music shop for the first time.
For a Sound Recording (or any other Resource) the same dates exists, alas the OriginalDigitalReleaseDate has been deprecated.
There are additional date fields that have been deprecated and should not be used any more:
GlobalReleaseDate
GlobalOriginalReleaseDate
OriginalDigitalReleaseDate (for Sound Recordings, Videos and other Resources).
OriginalDigitalReleaseDate
(c) Digital Data Exchange, LLC
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A survey on urinary incontinence among middle aged and older people
Takehiro Michikawa, Yuji Nishiwaki, Yuriko Kikuchi, Makiko Nakano, Megumu Takamizawa, Mieko Koike, Noriko Kikuchi, Yumi Mukoyami, Akemi Nakazawa, Yoshio Nishigaki, Toru Takebayashi
Department of Preventive Medicine and Public Health
OBJECTIVE: Studies in Western countries have revealed that urinary incontinence, non-intentional loss of urine, is a common condition in aged populations, and even younger individuals may suffer from urinary incontinence. However, in Japan, the evidence for community residents on this topic is limited. The aim of this study was to estimate the prevalence of urinary incontinence among middle aged using a structured questionnaire and older people and to provide useful information including frequency, voided volume, relation to parity as a risk factor and persons to consult for this condition. METHODS: The study subjects consisted of 985 residents, 350 males (mean age 62.5 +/- 11.2 years)and 635 females (64.3 +/- 11.4), who participated in annual health check-ups and answered a self-reported questionnaire on urinary incontinence. The questionnaire included questions on frequency, voided volume, condition-specific QOL score, self-diagnostic item (above four from Scored International Consultation on Incontinence Questionnaire-Short Form Japanese version), person to consult for this condition and parity (only for females). RESULTS: The proportion of those with urinary incontinence was 11.4% in males and 34.5% in females, and the proportion increased with age (P for trend <0.01). In females, the proportion was high, even in their forties (30.4%). In this study, parity was associated with urinary incontinence: compared to females with no childbirth experience, those giving birth to 4 or more children showed an odds ratio of 4.26 (95% CI: 1.13-16.10). In females, an increase in frequency of urinary incontinence negatively affected the QOL. When asked who they would consult, the majority of males answered either a medical institution (54.2%) or family (34.0%). In females, 39.6% reported a medical institution, 22.6% reported family, 16.5% reported no one, 10.6% reported health nurses other than in medical institutions and 9.5% reported friends. CONCLUSIONS: The study results showed that urinary incontinence is a common condition in this population. Particularly, a large proportion of females suffer from this condition, even in their forties. The study also revealed that urinary incontinence might negatively affect the QOL and that there are some individuals who do not consult (or intend to consult) anyone about their problem. This information might be useful for planning health policy on the topic in the future.
[Nippon kōshū eisei zasshi] Japanese journal of public health
Published - 2008 Jul
Referral and Consultation
Michikawa, T., Nishiwaki, Y., Kikuchi, Y., Nakano, M., Takamizawa, M., Koike, M., ... Takebayashi, T. (2008). A survey on urinary incontinence among middle aged and older people. [Nippon kōshū eisei zasshi] Japanese journal of public health, 55(7), 449-455.
A survey on urinary incontinence among middle aged and older people. / Michikawa, Takehiro; Nishiwaki, Yuji; Kikuchi, Yuriko; Nakano, Makiko; Takamizawa, Megumu; Koike, Mieko; Kikuchi, Noriko; Mukoyami, Yumi; Nakazawa, Akemi; Nishigaki, Yoshio; Takebayashi, Toru.
In: [Nippon kōshū eisei zasshi] Japanese journal of public health, Vol. 55, No. 7, 07.2008, p. 449-455.
Michikawa, T, Nishiwaki, Y, Kikuchi, Y, Nakano, M, Takamizawa, M, Koike, M, Kikuchi, N, Mukoyami, Y, Nakazawa, A, Nishigaki, Y & Takebayashi, T 2008, 'A survey on urinary incontinence among middle aged and older people', [Nippon kōshū eisei zasshi] Japanese journal of public health, vol. 55, no. 7, pp. 449-455.
Michikawa T, Nishiwaki Y, Kikuchi Y, Nakano M, Takamizawa M, Koike M et al. A survey on urinary incontinence among middle aged and older people. [Nippon kōshū eisei zasshi] Japanese journal of public health. 2008 Jul;55(7):449-455.
Michikawa, Takehiro ; Nishiwaki, Yuji ; Kikuchi, Yuriko ; Nakano, Makiko ; Takamizawa, Megumu ; Koike, Mieko ; Kikuchi, Noriko ; Mukoyami, Yumi ; Nakazawa, Akemi ; Nishigaki, Yoshio ; Takebayashi, Toru. / A survey on urinary incontinence among middle aged and older people. In: [Nippon kōshū eisei zasshi] Japanese journal of public health. 2008 ; Vol. 55, No. 7. pp. 449-455.
@article{a33c455651be488f947903094c9edf47,
title = "A survey on urinary incontinence among middle aged and older people",
abstract = "OBJECTIVE: Studies in Western countries have revealed that urinary incontinence, non-intentional loss of urine, is a common condition in aged populations, and even younger individuals may suffer from urinary incontinence. However, in Japan, the evidence for community residents on this topic is limited. The aim of this study was to estimate the prevalence of urinary incontinence among middle aged using a structured questionnaire and older people and to provide useful information including frequency, voided volume, relation to parity as a risk factor and persons to consult for this condition. METHODS: The study subjects consisted of 985 residents, 350 males (mean age 62.5 +/- 11.2 years)and 635 females (64.3 +/- 11.4), who participated in annual health check-ups and answered a self-reported questionnaire on urinary incontinence. The questionnaire included questions on frequency, voided volume, condition-specific QOL score, self-diagnostic item (above four from Scored International Consultation on Incontinence Questionnaire-Short Form Japanese version), person to consult for this condition and parity (only for females). RESULTS: The proportion of those with urinary incontinence was 11.4{\%} in males and 34.5{\%} in females, and the proportion increased with age (P for trend <0.01). In females, the proportion was high, even in their forties (30.4{\%}). In this study, parity was associated with urinary incontinence: compared to females with no childbirth experience, those giving birth to 4 or more children showed an odds ratio of 4.26 (95{\%} CI: 1.13-16.10). In females, an increase in frequency of urinary incontinence negatively affected the QOL. When asked who they would consult, the majority of males answered either a medical institution (54.2{\%}) or family (34.0{\%}). In females, 39.6{\%} reported a medical institution, 22.6{\%} reported family, 16.5{\%} reported no one, 10.6{\%} reported health nurses other than in medical institutions and 9.5{\%} reported friends. CONCLUSIONS: The study results showed that urinary incontinence is a common condition in this population. Particularly, a large proportion of females suffer from this condition, even in their forties. The study also revealed that urinary incontinence might negatively affect the QOL and that there are some individuals who do not consult (or intend to consult) anyone about their problem. This information might be useful for planning health policy on the topic in the future.",
author = "Takehiro Michikawa and Yuji Nishiwaki and Yuriko Kikuchi and Makiko Nakano and Megumu Takamizawa and Mieko Koike and Noriko Kikuchi and Yumi Mukoyami and Akemi Nakazawa and Yoshio Nishigaki and Toru Takebayashi",
journal = "[Nihon kōshū eisei zasshi] Japanese journal of public health",
publisher = "Nihon Eisei Gammai/Japanese Society of Public Health",
T1 - A survey on urinary incontinence among middle aged and older people
AU - Michikawa, Takehiro
AU - Nishiwaki, Yuji
AU - Kikuchi, Yuriko
AU - Nakano, Makiko
AU - Takamizawa, Megumu
AU - Koike, Mieko
AU - Kikuchi, Noriko
AU - Mukoyami, Yumi
AU - Nakazawa, Akemi
AU - Nishigaki, Yoshio
AU - Takebayashi, Toru
N2 - OBJECTIVE: Studies in Western countries have revealed that urinary incontinence, non-intentional loss of urine, is a common condition in aged populations, and even younger individuals may suffer from urinary incontinence. However, in Japan, the evidence for community residents on this topic is limited. The aim of this study was to estimate the prevalence of urinary incontinence among middle aged using a structured questionnaire and older people and to provide useful information including frequency, voided volume, relation to parity as a risk factor and persons to consult for this condition. METHODS: The study subjects consisted of 985 residents, 350 males (mean age 62.5 +/- 11.2 years)and 635 females (64.3 +/- 11.4), who participated in annual health check-ups and answered a self-reported questionnaire on urinary incontinence. The questionnaire included questions on frequency, voided volume, condition-specific QOL score, self-diagnostic item (above four from Scored International Consultation on Incontinence Questionnaire-Short Form Japanese version), person to consult for this condition and parity (only for females). RESULTS: The proportion of those with urinary incontinence was 11.4% in males and 34.5% in females, and the proportion increased with age (P for trend <0.01). In females, the proportion was high, even in their forties (30.4%). In this study, parity was associated with urinary incontinence: compared to females with no childbirth experience, those giving birth to 4 or more children showed an odds ratio of 4.26 (95% CI: 1.13-16.10). In females, an increase in frequency of urinary incontinence negatively affected the QOL. When asked who they would consult, the majority of males answered either a medical institution (54.2%) or family (34.0%). In females, 39.6% reported a medical institution, 22.6% reported family, 16.5% reported no one, 10.6% reported health nurses other than in medical institutions and 9.5% reported friends. CONCLUSIONS: The study results showed that urinary incontinence is a common condition in this population. Particularly, a large proportion of females suffer from this condition, even in their forties. The study also revealed that urinary incontinence might negatively affect the QOL and that there are some individuals who do not consult (or intend to consult) anyone about their problem. This information might be useful for planning health policy on the topic in the future.
AB - OBJECTIVE: Studies in Western countries have revealed that urinary incontinence, non-intentional loss of urine, is a common condition in aged populations, and even younger individuals may suffer from urinary incontinence. However, in Japan, the evidence for community residents on this topic is limited. The aim of this study was to estimate the prevalence of urinary incontinence among middle aged using a structured questionnaire and older people and to provide useful information including frequency, voided volume, relation to parity as a risk factor and persons to consult for this condition. METHODS: The study subjects consisted of 985 residents, 350 males (mean age 62.5 +/- 11.2 years)and 635 females (64.3 +/- 11.4), who participated in annual health check-ups and answered a self-reported questionnaire on urinary incontinence. The questionnaire included questions on frequency, voided volume, condition-specific QOL score, self-diagnostic item (above four from Scored International Consultation on Incontinence Questionnaire-Short Form Japanese version), person to consult for this condition and parity (only for females). RESULTS: The proportion of those with urinary incontinence was 11.4% in males and 34.5% in females, and the proportion increased with age (P for trend <0.01). In females, the proportion was high, even in their forties (30.4%). In this study, parity was associated with urinary incontinence: compared to females with no childbirth experience, those giving birth to 4 or more children showed an odds ratio of 4.26 (95% CI: 1.13-16.10). In females, an increase in frequency of urinary incontinence negatively affected the QOL. When asked who they would consult, the majority of males answered either a medical institution (54.2%) or family (34.0%). In females, 39.6% reported a medical institution, 22.6% reported family, 16.5% reported no one, 10.6% reported health nurses other than in medical institutions and 9.5% reported friends. CONCLUSIONS: The study results showed that urinary incontinence is a common condition in this population. Particularly, a large proportion of females suffer from this condition, even in their forties. The study also revealed that urinary incontinence might negatively affect the QOL and that there are some individuals who do not consult (or intend to consult) anyone about their problem. This information might be useful for planning health policy on the topic in the future.
JO - [Nihon kōshū eisei zasshi] Japanese journal of public health
JF - [Nihon kōshū eisei zasshi] Japanese journal of public health
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combat desertification, deforestation, governance, land cover change, land use policies, rural communities, rural populations, social science
(-) combat desertification (15)
(-) deforestation (12)
(-) rural populations (6)
(-) land cover change (4)
Women on the Front Lines of Halting Deforestation
In Zimbabwe, the bulk of rural communities and urban poor still get their energy supplies from the forests, leading to deforestation and land degradation. The Zimbabwe Environmental Law Association (ZELA) 2016 review on forest policies in the country found that fuel wood accounted for over 60…
OECD Monitoring land cover change
Loss of biodiversity and pressures on ecosystem services are global challenges. Land cover change is the best measure available to monitor pressures on terrestrial ecosystems and biodiversity. The OECD is developing new indicators on land cover changes and conversions.
Towards estimates of future rainfall erosivity in Europe based on REDES and WorldClim datasets
The policy requests to develop trends in soil erosion changes can be responded developing modelling scenarios of the two most dynamic factors in soil erosion, i.e. rainfall erosivity and land cover change. The recently developed Rainfall Erosivity Database at European Scale (REDES) and a statistical…
FAO State of Food and Agriculture Report Focuses on Making Migration Work for All
The report aims to improve the understanding of the causes, costs and benefits of migration to support integrated policies. It shows that migration is an important part of rural development that should be managed rather than prevented. Policies should aim to ensure that migration is a choice and to…
Great Insights Magazine - the new issue: North Africa, hope in troubled times
North Africa was the birthplace of the Arab uprisings in late 2010. This movement affected all the countries in the region, albeit to varying degrees. And while protestors asked in unison for deep political and economic changes, the various governments in North Africa responded differently to their…
OpenForests-The interactive map-based platform is designed to present forest and landscape projects and tell their stories
OpenForests (https://openforests.com), an innovative German forest consulting and tech company, has officially launched the explorer.land platform on the 1st of November. The interactive map-based platform is designed to present forest and landscape projects and tell their stories while connecting…
Just published : Latest articles form the new issue Land Degradation & Development, Vol. 29, No. 12, December 1, 2018
RESEARCH ARTICLES Open Access Enantioselectivity in degradation and ecological risk of the chiral pesticide ethiprole Qing Zhang, Wu Xiong, Beibei Gao, Zachary Cryder, Zhaoxian Zhang, Mingming Tian, Edmond Sanganyado, Haiyan Shi, Minghua Wang Pages: 4242-4251 | First Published: 02 October 2018…
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Apple Mac Pro pre-orders start today so sell some organs and buy one
How much is a kidney worth?
Curtis Silver
Image: KnowTechie
Back in June, Apple finally announced a new Mac Pro slated for release later in the year. Well, now it’s later in the year and pre-orders start today. This is a professional machine for professionals, not just some computer for you schlubs to watch porn.
Apple is not trying to hide the fact that this computer is designed and priced for high-level consumers and design professionals. In demos this year, Apple tailored the Mac Pro performance as optimized for those who make movies or edit music. Not your Soundcloud raps, but professional-level editors. Because as much as you might salivate for the Mac Pro, you can’t fucking afford it.
The Mac Pro starts at $5,999. And while you can stop there, most PC buyers know that beefing the specs is half the fun. But then you have to buy a display. How about the intended display for the Mac Pro? The 6K Pro Display XDR is only $4,999 after all. That’s only $1,000 less than the base Mac Pro. Like I said, this computer is not for you.
As much as the tech press is slapping their engorged genitals all over their keyboards slobbering over this machine, it’s just not a consumer-friendly piece of tech
That’s fine. Major studios and professionals need computers too. But there’s no way Apple could just quietly release a Mac Pro into the wild without the lot of us popping fluids into our pants.
Yet, even if you have a MacBook, iMac or Mac Mini, you probably want a Mac Pro. You are probably looking at financing options or re-adjusting your mortgage in order to afford the Mac Pro. Because it’s as much a status symbol as it is anything else.
To be fair, it is stacked as far as internal statistics, so it’s not just the Apple brand that is jacking up the price. Yet, the stats are listed as “up to” so yeah, if you want a Mac Pro and think you can afford it after spending the last few months selling your blood, a kidney, your car, your firstborn and your house, then go for it.
I’m not a huge fan of Apple (as if that isn’t apparent after a decade of publicly shitting on Apple) but its Mac Pro is a hell of a machine. If I was rich and didn’t need it, I’d buy it to watch porn and surf the internet and maybe do a spreadsheet. But I’m not. And I’m not going to steal a tow truck and rip out an ATM from a bank drive-thru in order to afford a Mac Pro.
What would you do for a Mac Pro? If you’ve done it already, go spec one out and let me know if it changes your life for the better.
What do you think? Are you interested in the Mac Pro? Would you get one if you had the cash? Let us know down below in the comments or carry the discussion over to our Twitter or Facebook.
Editors’ Recommendations:
Apple is reportedly working on an iPhone without any ports and it’s launching in 2021
Here’s why your iPhone 11 Pro is STILL requesting location data without your permission
Snapchat is launching a new Cameo feature that puts your face into videos
Tech Hangover: Peloton can’t catch a break
Related Topics6K displayApplemac proMacBookNewspre-orders
Writing about consumer technology, social media and the deep layers of psychological torture endured by all of it. The world is changing, but that doesn't mean we can't be cynical about it. It's not all sunshine and roses in Silicon Valley. It's self loathing, pretentiousness and machines that squeeze juice for you. Also, a strong affinity for toasters.Follow on Twitter @cebsilver for them jokes. Chaotic neutral. Pitches to cebsilver@gmail.com
Ford wants to replace your UPS driver with a robot
Fortnite now has 120 FPS on iPad Pro and the Twitter community is having a meltdown
Thought VR and AR were fads? CES would like a word with you
I spent a month playing Project xCloud and it kicked ass
Segway made a self-balancing vehicle like the ones from the movie Wall-E
More in Apple
The best iPhone XR cases
Lots of great options here.
Dell is working on a new feature that lets iPhone users control their phone from their laptop
The feature will not release until Spring 2020.
Apple is secretly working on wireless tech that uses satellites to beam data directly to its devices
It's basically Apple's own internet.
How to activate an iPhone without a SIM card
No SIM card? No problem.
You can now get a yearly subscription to Apple Arcade for just $50
If you use the service, this is a solid option.
Apple’s new parental iPhone feature doesn’t work that well – Apple is working on a fix
How do you release a safety feature that doesn't work?
How to change the language on an iPad if it’s in a language that you can’t read
Don't worry, we've included pictures to make the process extremely straightforward.
MacOS Catalina broke a bunch of Adobe products – here are the best alternatives to check out
There are a few standout options available.
China doesn’t want its government agencies using any US-made technology
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November 28, 2010 ldcclub LDC Columnists
Former Conservative Senator Warns About GOP Radicalism
Think Progress highlights a comment made by former Senator John Danforth that should worry everyone who has an iota of concern about a functioning federal government.
In a New York Times story about the problems the Obama Adminstration and sane Republicans like Sen. Dick Lugar (R-Indiana) are having getting the new START nuclear arms treaty with Russia ratified, we find this paragraph that is only astonishing to people who have not been paying attention:
“If Dick Lugar,” said John C. Danforth, a former Republican senator from Missouri, “having served five terms in the U.S. Senate and being the most respected person in the Senate and the leading authority on foreign policy, is seriously challenged by anybody in the Republican Party, we have gone so far overboard that we are beyond redemption.” (emphasis by Think Progress)
Mr. Danforth, who was first elected the same year as Mr. Lugar, added, “I’m glad Lugar’s there and I’m not.”
Remember, this is the Senator who helped ensure Clarence Thomas was confirmed. Senator Danforth was not exactly a swishy moderate.
It really would be stunning to see Dick Lugar primaried. And, as Think Progress explains, it is a realistic prospect. I think we really should be worried about what this says about the ability of our federal government to function during this time of economic and political crisis.
The world does not stop for tea parties.
Tagged nuclear arms, radical right, START, tea party
Who Needs An Economic Policy Anyway?
What Can We Do in 2011? A Conversation with Asm. Nancy Skinner to Headline January 13 Club Meeting
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Part 7 Characters, Stand Users, Main Allies,
Living Characters in Part 7
Pendleton Family
Characters of Unknown Fate
ルーシー・スティール
Rūshī Sutīru
Lucy Pendleton[1] (Maiden name)
Lucy in the Sky with DiamondsW (Beatles Song)
~1876
Under 51 kg[3]
Blonde (Digital Color)
Aquamarine (ASB)
Blue (Digital Color)
Steven Steel (Husband)
Silas Pendleton (grandfather)
Mary Pendleton (grandmother)
Adam Pendleton (father)
Alice Pendleton (mother)
Tom Pendleton (older brother)
Will Pendleton (younger brother)
Liza Pendleton (younger sister)
Reggie Pendleton (younger sister)
Charles Pendleton (younger brother)
SBR Chapter 1 - The Steel Ball Run: Press Conference
SBR Chapter 95 - The World of the Stars and Stripes -Outro
Hoko KuwashimaW (All Star Battle / Eyes of Heaven)
“ If you're going to plan a race, it should be across the entire American continent! And the winnings should be huge! Like, $50,000,000! Real dreams should be that big! ”
—Lucy Pendleton to her future husband, Steven Steel
Lucy Steel (ルーシー・スティール, Rūshī Sutīru), née Lucy Pendleton (ルーシー・ペンドルトン, Rūshī Pendoruton) is a side character and ally featured in Steel Ball Run.
Lucy is the wife of the Steel Ball Run race promoter, Steven Steel. She eventually discovers Funny Valentine's plan for the race and, fearing for her husband's safety, decides to cooperate with the Joestar Group.
Lucy is a fourteen-year-old girl of average height and build. She has light, medium-length hair and an outfit generally consisting of a dress and striped tights. She also wears arm warmers and tall boots, both adorned with circular decorations.
Later, after she is kidnapped by Funny Valentine, her outfit is simplified to only a dress and pair of pumps, and her hair is slightly longer than before. In SBR Chapter 95, Lucy is seen wearing a hood, while also regaining her arm warmers and boots but without any tights underneath.
Lucy is an intelligent, gentle and courageous girl despite facing many dangerous situations.
Already apparent in her childhood, Lucy's kindness pushed her to talk to a then derelict Steven Steel, being the first person to support him in his idea of organizing a horserace and also suggesting that it had an enormous scale by making it go across the United States and having a prize in the millions[4]. When Steven repaid her kindness by preventing the mafia from taking her away, Lucy was deeply grateful to Steven, developing a deep relationship with him although it would remain platonic despite everyone else's bias[5].
Lucy isn't shown interacting much with other people, usually being rather withdrawn compared to Steven's bombastic public persona. However, she is the only one who knows about his moments of doubt and sadness and during them encourages her husband[6]. When interacting with other people, Lucy usually acts polite and rather meek.
As Steven's wife, Lucy is extremely loyal to him and her every action during the course of the Steel Ball Run is performed in order to protect him from danger. As such, despite being a frail and Stand-less person, Lucy constantly throws herself into dangerous actions without hesitation. Not only does she infiltrate several well-protected facilities in order to undermine Funny Valentine[7][8], she also has several perilous encounters against Stand Users such as Blackmore[9], Mike O.[10] or even Diego Brando[11], all of whom try to kill her. She also plainly rejects Mountain Tim's advances, stating her pride in being Steven's wife[12].
Although she is prone to nervousness, Lucy is also an extremely resourceful woman, being adept at tricking people or performing other tricks to escape notice. She knows lip-reading[13] and is a competent actor, which in conjunction with her status as the main promoter's wife, allows her to access several usually secure places. Even on the brink of capture or worse, Lucy can think of ways to escape using all available tools and allies. Lucy is ultimately the one who defeats Diego Brando by bringing his alternate self's head to him, killing him in spite of his formidable Stand[14]. Despite her gentle nature, Lucy also doesn't hesitate to fire at Blackmore[15] or stab Valentine[16], showing a hidden ruthless side to her.
See also: Ticket to Ride
Funny Valentine identifies Lucy as compatible with the Saint's Corpse and catalyzes a merger and metamorphosis between the two. A temporary stand is created after the corpse fuses itself with Lucy, gathering inside her and taking over her bodily functions. While enacted, the stand provides divine protection, which Funny uses to his advantage during his fight with the protagonists.
Lucy is a lip reader, enabling her to spy on people and determine what they are saying purely through lip movement. It allowed her to know about the secret message Ringo Roadagain sent to Valentine and intercept it before the President.
Lucy lived in a family of six siblings and was the second eldest of the bunch. Her father, Adam Pendleton, was a farmer who owned a small land in Oklahoma. Lucy's mother, Alice, died at age thirty-seven when Lucy was only twelve, after which the family fell into misfortune. Lucy's father would later contract debt from the mafia and, being unable to bear having his land or eldest son taken from him, offered Lucy to them instead.[1]
However, sometime prior to the event, Lucy met Steven Steel on the streets, where he was broke and drunk, listening to him mumbling about his plan of Steel Ball Run, and gave him the suggestion to run it. It was then that Steven stepped in to repay the favor he owed Lucy. To save Lucy from working as a prostitute for the mafia, Steven told Lucy's father to tell the mafia that Lucy was previously defiled by him.
Indebted to the man, twelve year old Lucy Pendleton tells Steven that she "doesn't mind", and could be his "real wife" someday. Steven denies this firmly, and reassures the young girl that he won't ever lay a hand on her-- asking only that she spare him the trouble of "her future boyfriend" being a mafia member.
In the years leading up to the Steel Ball Run, Steven and Lucy develop an intense and platonic bond of trust.
As Steven Steel's wife, Lucy doesn't involve herself in the race, but nonetheless accompanies her husband to provide him moral support. During the 3rd Stage, she eavesdrops on President Funny Valentine talking about the Saint's Corpse and discovers the true purpose of the race.[17] While keeping an eye on the president, she foresees the government eventually killing Steven, prompting her to steal the coordinates to the Corpse Part near Kansas City. She is noticed, but barely escapes the government building with the help of Mountain Tim. She is followed, however, by Blackmore, one of Valentine's Subordinates.[18]
Lucy reaches the location of the Corpse Part and digs up the Spine, but Blackmore soon catches up with her. At this point, a manifestation of the Corpse's power appears, allowing Lucy to shoot Blackmore and escape toward Gyro Zeppeli and Johnny Joestar. The duo manage to finish off the agent and persuade Lucy to hinder Valentine by stealing his Corpse Parts[19].
As the investigation on the infiltrator closes in on her, Lucy and Hot Pants decide to cooperate and infiltrate Valentine's current residence, but ultimately fail to steal his Corpse Parts. Thanks to Cream Starter, Lucy disguises herself as the president's wife, Scarlet Valentine, who was killed during the infiltration.[20] However, Lucy is quickly discovered by Funny Valentine who tries to rape her, causing Lucy to blow her cover and attack the President in self-defense. While running away from the president, she stumbles upon the stolen Corpse parts and becomes pregnant, discovering the Corpse's head in her womb.
After she is impregnated with the Corpse's head, she later absorbs all the other Corpse parts. Afterwards, she begins to metamorphose and apparently gains a Stand power. However, she mostly remains unconscious, with Funny Valentine using her Stand's power to protect himself.
After Funny Valentine is defeated at the hands of Johnny and the completed Corpse removed itself from her body, she is reunited with Steven. However, Johnny notices that the Corpse had just been taken by someone working with Funny Valentine and chases after him to reclaim it. Lucy notices that the horse tracks start from the hole Funny Valentine left in his wake and puts together that the thief is in fact Diego Brando from another dimension, whom she plans to confront at the shelter that was made to house the Corpse should Johnny fail to retrieve it first. Remembering what Valentine said about the effects objects from one dimension meeting itself, she uses the base world's Diego Brando's severed head to defeat him.
SBR Chapter 1: "The Steel Ball Run: Press Conference"
SBR Chapter 4: "September 25, 1890 - 3 Hours to Start"
SBR Chapter 5: "First Stage: 15,000 Meters"
SBR Chapter 6: "The Dried-Up River; Diego Brando"
SBR Chapter 10: "The Final Stretch: 2,000 Meters Left"
SBR Extra Chapter 1: "~How the Steel Ball Run Race Got Started~"
SBR Chapter 12: "First Stage: Disqualified from Victory"
SBR Chapter 13: "The Sheriff's Request to Mountain Tim"
SBR Chapter 24: "Interlude" (Cover only)
SBR Chapter 25: "Tusk, Part 1"
SBR Chapter 28: "Scary Monsters, Part 1"
SBR Chapter 36: "The Green Tomb, Part 1"
SBR Chapter 38: "Catch the Rainbow (On a Stormy Night...), Part 1"
SBR Chapter 40: "Silent Way, Part 1"
SBR Chapter 47: "The Land of Promises: Sugar Mountain, Part 3" (Cover only)
SBR Chapter 48: "Tubular Bells, Part 1"
SBR Chapter 50: "Tubular Bells, Part 3" (Disguised as Scarlet Valentine)
SBR Chapter 54: "Wrecking Ball, Part 4" (Mentioned only)
SBR Chapter 55: "The Victor's Rights" (Mentioned only)
SBR Chapter 56: "Civil War, Part 1" (Disguised as Scarlet Valentine)
SBR Chapter 59: "A Dream of Gettysburg" (Mentioned only)
SBR Chapter 60: "Both Sides Now, Part 1" (Disguised as Scarlet Valentine)
SBR Chapter 62: "Dirty Deeds Done Dirt Cheap"
SBR Chapter 64: "Chocolate Disco, Part 1" (Description only)
SBR Chapter 67: "D4C, Part 2" (Mentioned in flashback(s))
SBR Chapter 68: "D4C, Part 3"
SBR Chapter 69: "D4C, Part 4" (Mentioned only)
SBR Chapter 71: "Ticket to Ride, Part 1"
SBR Chapter 77: "D4C, Part 10"
SBR Chapter 78: "D4C, Part 11 -Love Train-"
SBR Chapter 83: "Ball Breaker, Part 1"
SBR Chapter 88: "Break My Heart, Break Your Heart, Part 1"
SBR Chapter 90: "High Voltage, Part 1"
SBR Chapter 95: "The World of the Stars and Stripes -Outro"
Lucy Steel appears a stage hazard on the ATLANTIC OCEAN stage as Lucy Steel's Ticket to Ride grants a full Heart Heat Gauge for whoever reaches it first.
Lucy Steel appears to be the Steel Ball Run version of Erina Pendleton, a major character from Part 1.
SBR Volume 12"> SBR Volume 13"> SBR Volume 17"> SBR Volume 20"> SBR Volume 22"> SBR Chapter 37"> SBR Chapter 41; Wears Cowboy hat and Pantyhose"> SBR Chapter 49"> SBR Chapter 50"> SBR Chapter 59"> SBR Chapter 61; Disguised as Scarlet Valentine"> SBR Chapter 71"> SBR Chapter 73"> SBR Chapter 78; Displaying Ticket to Ride"> SBR Chapter 80; emblem"> SBR Chapter 90"> SBR Chapter 95">
Ultra Jump May 2006">
her Stand in All Star Battle">
↑ 1.0 1.1 SBR Chapter 61: Both Sides Now (2)
↑ SBR Chapter 64: Chocolate Disco (1)
↑ SBR Chapter 48: Tubular Bells (1)
↑ SBR Extra Chapter 1: "~How the Steel Ball Run Race Got Started~", p6
↑ SBR Chapter 61: "Both Sides Now, Part 2", p2-11
↑ SBR Chapter 1: "The Steel Ball Run: Press Conference", p35
↑ SBR Chapter 36: "The Green Tomb, Part 1", p33
↑ SBR Chapter 48: "Tubular Bells, Part 1", p70
↑ SBR Chapter 38: "Catch the Rainbow (On a Stormy Night...), Part 1", p2
↑ SBR Chapter 95: "The World of the Stars and Stripes -Outro", p10
↑ SBR Chapter 38: "Catch the Rainbow (On a Stormy Night...), Part 1", p14
↑ SBR Chapter 61: "Both Sides Now, Part 2", p49
↑ SBR Chapter 28: "Scary Monsters, Part 1"
↑ SBR Chapter 37: "The Green Tomb, Part 2"
↑ SBR Chapter 40: "Silent Way, Part 1"
↑ SBR Chapter 50: "Tubular Bells, Part 3"
v · d · eSteel Ball Run Characters
Pocoloco
Diego "Dio" Brando
Andre Boom Boom
Benjamin Boom Boom
L. A. Boom Boom
Oyecomova
Pork Pie Hat Kid
Dr. Ferdinand
Ringo Roadagain
Mike O.
Eleven Men
Magent Magent
Axl RO
D-I-S-C-O
Alternate Diego Brando
Scarlet Valentine
Gregorio Zeppeli
George Joestar
Nicholas Joestar
Diego's Mother
Norisuke Higashikata
Brando Family
Boom Boom Family
Retrieved from "https://jojo.fandom.com/wiki/Lucy_Steel?oldid=339598"
Stand Users
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Large-Scale Comparative Genomic Ranking of Taxonomically Restricted Genes (TRGs) in Bacterial and Archaeal Genomes
Gareth A. Wilson ,
*To whom correspondence should be addressed. E-mail: gawi@ceh.ac.uk
Affiliation Centre for Ecology and Hydrology (CEH) Oxford, Oxford, United Kindgom
Edward J. Feil,
Affiliation Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom
Andrew K. Lilley,
Dawn Field
Gareth A. Wilson,
Gareth A. Wilson Edward J. Feil Andrew K. Lilley Dawn Field
Lineage-specific, or taxonomically restricted genes (TRGs), especially those that are species and strain-specific, are of special interest because they are expected to play a role in defining exclusive ecological adaptations to particular niches. Despite this, they are relatively poorly studied and little understood, in large part because many are still orphans or only have homologues in very closely related isolates. This lack of homology confounds attempts to establish the likelihood that a hypothetical gene is expressed and, if so, to determine the putative function of the protein.
We have developed “QIPP” (“Quality Index for Predicted Proteins”), an index that scores the “quality” of a protein based on non-homology-based criteria. QIPP can be used to assign a value between zero and one to any protein based on comparing its features to other proteins in a given genome. We have used QIPP to rank the predicted proteins in the proteomes of Bacteria and Archaea. This ranking reveals that there is a large amount of variation in QIPP scores, and identifies many high-scoring orphans as potentially “authentic” (expressed) orphans. There are significant differences in the distributions of QIPP scores between orphan and non-orphan genes for many genomes and a trend for less well-conserved genes to have lower QIPP scores.
The implication of this work is that QIPP scores can be used to further annotate predicted proteins with information that is independent of homology. Such information can be used to prioritize candidates for further analysis. Data generated for this study can be found in the OrphanMine at http://www.genomics.ceh.ac.uk/orphan_mine.
Citation: Wilson GA, Feil EJ, Lilley AK, Field D (2007) Large-Scale Comparative Genomic Ranking of Taxonomically Restricted Genes (TRGs) in Bacterial and Archaeal Genomes. PLoS ONE 2(3): e324. https://doi.org/10.1371/journal.pone.0000324
Academic Editor: Cecile Fairhead, Pasteur Institute, France
Received: January 26, 2007; Accepted: February 18, 2007; Published: March 28, 2007
Copyright: © 2007 Wilson et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: This work was funded through a Natural Environment Research Council Ph.D studentship awarded to GW (NER/S/A/2003/11341).
The availability of hundreds of complete bacterial genome sequences has made it possible to explore how the evolutionary diversification of gene content reflects the ecological needs and opportunities of different taxa. It is well known that the gene content of bacterial and archaeal genomes can vary widely and that only a very few genes are truly universal [1]–[3]. As a consequence, genes can differ significantly in their taxonomic distributions, with more broadly conserved genes having ‘housekeeping’ functions and less conserved genes being responsible for the phenotypic differences observed between organisms. Lineage-specific, or “taxonomically restricted” genes (TRGs), are defined as being exclusively restricted to a particular taxonomic group [4]. In such a framework, genes may be TRGs at any taxonomic level (i.e. domain-, family, genus-, species- or strain-specific). TRGs at the species and strain-levels are of most interest in the search for genotypes which help define exclusive ecological adaptations to particular niches.
The study of narrowly distributed TRG's is confounded by the fact that many are short, repetitive or have unusual A+T contents [5], and the assumption that many such short coding sequences (CDS) represent annotation errors [6]. Over-annotation of genomes, resulting in an excess of small predicted proteins is clearly evident in certain genomes (e.g the initial annotation of Aeropyrum pernix [7]) and is proposed to be an unfortunate feature of many genomic annotations [6], [8], [9]. This overannotation could mask intergenic regions containing small non-coding RNAs. It is also possible that many TRGs remain ‘orphaned’ for no other reason than the sampling bias in public genome databases [10]. It is well-known that the current collection is highly biased towards certain organisms (most notably pathogens, γ-Proteobacteria, and Firmicutes) [11]. This results in the trend that taxonomic isolation is correlated with an increased percentage of orphans [8]. It is therefore expected that homologues for many orphan predicted proteins in taxonomically isolated lineages that lack close relatives in genomic databases will be found once the taxonomic gaps in the genomic database begin to be filled [10].
Despite potential errors in our current estimation of the numbers and identities of narrowly distributed TRGs, there is growing evidence that many, including those that are currently orphaned, are of biological significance. Hence there is a growing need to untangle erroneous CDS from authentic species- and strain-level TRGs [12]–[14]. Dispersed examples of the latter are most frequently found as the result of in depth in silico [5] or empirical studies [12] of a particular organism or small group of organisms. Increasingly, examples are being identified as the result of whole genome sequencing [14]. One example to come from complete genome sequencing is the TCP virulence locus of Vibrio cholerae Tor N16961. Once a cluster of largely orphaned CDS, a homologous region has recently been found in the squid symbiont Vibrio fischeri [15]. The TCP genes code for the toxin co-regulated pili in V. cholerae and serve as its critical intestinal colonisation factor, providing the receptor for entry of the temperate filamentous phage CTXΦ, which contains the cholera toxin genes, ctxAB [16] into the cell [17]. Likewise, the sequencing of many genomes is confirming the presence of many strain-specific genes which form the “pan-genome” of many species [18], [19].
Given the potential significance of orphaned and narrow-range TRGs and the confounding sources of error associated with currently annotated genomes, it is clear that a reliable objective measure of the potential ‘quality’ of a given CDS would be useful [See 20 for the scoring of CDS with homology]. This could be used to prioritize it either as a candidate for further characterization or as an error. Motivated by this requirement, and with a specific focus on orphans and narrow-range TRGs, we have devised a scoring system that allows the ‘ranking’ of predicted proteins based on a variety of features, reflecting the likelihood that a given CDS encodes a protein.
We previously reported that the absolute number of single-copy TRGs from the complete and published genomes of Bacteria and Archaea is increasing [4]. The most phylogenetically and ecologically unique species contribute the most unique genes, in part due to undersampling of these genetic lineages [4]. For that study we generated two datasets. The first contained all orphans as defined by BLAST (using a threshold of 10−3), the second applied an arbitrary length cutoff of ≥150 amino acids and excluded all CDS with low complexity (highly repetitive) regions to remove likely CDS enriched in artefacts. The method of scoring CDS described here extends this ‘selective filtering’ approach and is called the ‘Quality Index for Predicted Proteins’ (QIPP). We describe the use of QIPP as it is applied to the reanalysis of this data set based on the inclusion of five criteria selected for their presumed ability to detect purifying selection and CDS which are unlikely to occur by chance alone. These are length [6], percentage low complexity (a measure of the degree of repetition) [21], difference in G+C composition of sequence and genome [22], average amino acid cost [23], [24] and neighbourhood distribution (ND) [25].
The orphan and non-orphan components of many proteomes have different overall characteristics
To examine whether orphaned CDS, which are expected to be on average smaller [6] and more A+T rich [5], [26] have significantly different QIPP scores than non-orphans, we re-examined our original data set [4]. QIPP scores were calculated for each protein in this data set of 122 proteomes [4] as described in the Materials & Methods. In total, the distributions of all five criteria (length, low complexity, G+C content, amino acid cost and neighbourhood distribution (Table 1)) differ significantly between orphans and non-orphans in 61 of the 122 species examined (p<0.05, Mann-Whitney). 3 or more criteria are significant in 117/122 species. Four of the remaining five species contained fewer than 10 orphans, and when all such genomes (n = 6) were excluded 115 of the remaining 116 species had orphans that differed significantly from the non-orphans for three or more criteria. The strikingly different values for Escherichia coli K12 can be seen in Figure 1 as an example of these trends. The distribution of the QIPP scores for orphan and non-orphan TRG's were found to be significantly different for 119 of the 122 genomes (p<0.05, Mann-Whitney). The remaining three genomes contained 2 or less orphans and thus could not provide significant discriminatory power. Overall, the QIPP scores for all orphan (mean = 0.38, +0.14) and non-orphan (mean = 0.54, +0.14) TRG's were significantly different (p = 0.000, Mann-Whitney). These results confirm that the criteria used for the QIPP scores can reliably distinguish between “orphan-like” (less well conserved) and “non-orphan-like” (more widely conserved) genes.
Figure 1. Distributions of orphans and non-orphans in E.coli K12.
The predicted proteins in E.coli K12 that were found to be unique (light gray) when compared to 122 bacterial proteomes (shown in Table S1) were designated as orphans (n = 174). All remaining proteins (dark gray) were non-orphans (n = 4137). Distributions of values for both groups were calculated as a percentage for (a) length, (b) percent low complexity, (c) G+C difference from the mean, (d) Cost and (e) Neighbourhood Distribution.
Table 1. Criteria used for the calculation of QIPP
Ranking orphan CDS using QIPP scores
The distribution of QIPP scores across the orphans in this data set was examined to determine if there was sufficient variation to rank them. Figure 2a shows that QIPP scores range from 0.0 to 0.9 (out of a possible range from zero to one) and so the index does have discriminatory power. The overall QIPP scores for each proteome deviate from the normal distribution for all five reference genomes, with too few high-scoring CDS and a longer than expected left-hand tail of low-scoring proteins (Darling-Anderson p<.005). This is due to the fact that for each criterion (with the exception of low complexity) there are few proteins with very high ranks (Figure 2b–f).
Figure 2. QIPP and Criterion Distributions of orphans in 122 bacterial genomes.
The orphans (n = 43513) obtained from 122 bacterial genomes were scored and the distribution plotted according to (a) QIPP and the individual criteria that constitute QIPP: (b) length, (c) percent low complexity, (d) G+C difference from the mean, (e) cost and (f) Neighbourhood Distribution.
We then examined the quality of the highest-scoring orphans to see if our list contained a significant number of potentially ‘authentic’ orphans–i.e. those unlikely to occur by chance. The extreme right hand distribution of these QIPP scores contains a total of 2,010 single-copy TRGs (≥95th percentile with a minimum score of 0.62), 1,260 are longer than 200 amino acids, a criterion that when used in isolation, is generally accepted to signify ‘authentic’ CDS [6]. Relaxing the QIPP score threshold, and using only length as a criterion, a total of 9858 (22.66%) single-copy TRGs are found in this data set which are ≥200 amino acids. A subset of these, 2,445 (5.62%), are ≥400 amino acids.
When interpreting the origins of such high-quality single-copy TRGs, the taxonomic uniqueness of each parent genome must be considered. Of those with QIPP scores above the 95th percentile (> = 0.62), only 467 (23%) are from 62 species (8 per genome) sampled down to the species level (i.e. another species from the same genus is available in the data set) (average QIPP score = 0.66). In contrast, 1,543 (77%) originate from 60 species which only have more distant relatives in this data set. It is presumed that these genomes include many TRGs exclusive to higher taxonomic levels; 24 genomes are unique at the genus level (259 orphans, 11 per genome, average QIPP score = 0.66), 30 at the family level (931 orphans, 31 per genome, average QIPP score = 0.67) and 6 at the division level (353 orphans, 59 per genome, average QIPP score = 0.67). Of those larger than 200 amino acids, 2,878 (29%) are from 62 species (46 per genome) sampled down to the species with an average QIPP score of 0.43. The remaining 6,980 (71%), originate from 60 species unique at the genus level (1,439 total, 60 orphans per genome, average QIPP score = 0.44), the family level (4,263 total, 142 orphans per genome, average QIPP score = 0.48) and the division level (1,278 total, 213 orphans per genome, average QIPP score = 0.50).
When plotted against genetic similarity, more distantly related genomes contribute on average more high-quality, single-copy TRGs (Table S1 and Figure S1). Chi-squared tests were used to identify genomes that made a greater contribution than expected to the top 50% of the ranked list (Figure 3). Genomes that did not contain enough orphans (>5) to perform a chi-squared test were removed from the analysis (n = 6). Genomes that contribute more high ranking QIPP scores are more distantly related (Figure 3, Anova p = 0.000) but only a low proportion of variability in top-ranking scores is explained by a regression analysis (p = 0.000, R-squared = 10.63%).
Figure 3. Genomes which are more taxonomically isolated have larger numbers of high-scoring orphan predicted proteins.
Chi-squared tests were used to determine which genomes had significantly more predicted proteins in the top 50% of the list of ranked orphan predicted proteins than would be expected by chance (−1 = significantly less orphans than expected in top 50% rank, 0 = no significant difference and 1 = significantly more orphans than expected in top 50% rank).
Less conserved genes have lower QIPP scores
The difference between orphan and non-orphan QIPP scores suggests that it might be possible to predict a priori how conserved a particular CDS might be using QIPP scores in the absence of homology. To explore this further, we selected a subset of five reference genomes from the best-sampled taxa in our original dataset for which intra-specific comparisons yielding high numbers of strain-specific orphans were also available (Table 2). For each reference genome the taxonomic distribution of all predicted proteins at the Archaea/Bacteria level, domain, division, family, genus, species and strain level (Figure 4) was determined.
Figure 4. Calculated QIPP scores for 5 bacterial genomes split into taxonomic classes.
Every predicted protein in (a) E.coli K12, (b) H.pylori 26695, (c) N.meningitides MC58, (d) P.marinus CCMP1375 and (e) V.vulnificus CMCP6 was put into the taxonomic level at which it was restricted and scored according to QIPP.
Table 2. Numbers and percentages of species-specific and strain-specific genes after the addition of a second strain in five bacterial species.
The average QIPP scores and percentages of predicted proteins exclusive to each of these taxonomic levels are given in Table 3. Overall, average scores are relatively uniform across the five genomes at each of the 7 taxonomic levels examined. Scores range from an average of 0.60 for proteins conserved across bacteria and archaea down to 0.35 for proteins conserved at the strain-level. These average scores are significantly different across TRG's exclusive to different taxonomic levels (Anova, p = 0.000 for every genome). The data show an overall decrease in QIPP score as the degree of conservation narrows (Figure 4). For the five genomes, when all CDS are taken into account, a regression analysis provides a p-value of 0.000 with R-squared values ranging from 20.3% to 36.3%.
Table 3. Table showing the average QIPP score for predicted proteins at each taxonomic level for five selected bacterial genomes.
The differences in mean QIPP scores between different groups of TRG's are largest for comparisons between groups of CDS conserved above the level of division and those conserved at the species- and strain-level (Table 3). Still, average QIPP scores, are significantly different between all higher TRG groups when compared to the average for species-level TRGs, while groups of species- and strain-level TRGs cannot be distinguished (Table 4). Interestingly, scores from the gene prediction software Glimmer could be used to separate only 7 of the 15 comparisons presented in Table 4. Hence QIPP provides additional information which is useful for post-processing gene predictions such as those made by Glimmer, in the absence of homology.
Table 4. Statistical significance of QIPP (Q) and Glimmer (G) scores when differentiating between species-specific genes and a respective taxonomic rank.
In addition to using QIPP to rank individual CDS, we also investigated whether the data had biological meaning. Using quartile analysis, 50% of the CDS in each of these genomes fall uniformly between the absolute values of 0.43 and 0.64 (Table 3), suggesting rule of thumb cut-offs for QIPP scores associated with the least (below 0.43) and most (above 0.64) highly conserved CDS in a genome. The data further suggest that the most extreme values of QIPP have the highest degree of predictive power for level of conservation (Figure 4). For example, using a minimum threshold score of ≥0.8, 98% of all CDS are members of the most conserved gene families (above the division-level). A total of 58% of CDS with scores less than 0.2 are species- and strain-specific TRGs.
To observe the range of QIPP scores that might be expected from the most highly conserved CDS we examined a subset of universally conserved genes [3]. We found the homologues of these 31 previously defined protein families [3] in the E. coli K12 genome and examined their QIPP scores. These QIPP scores range from 0.5 to 0.87 with a mean of 0.69 (±0.099). A large number of these proteins are ribosomal proteins, which are all of shorter than average size for E. coli. QIPP score is very poorly correlated with the overall length of these proteins (R-squared = 0.012) suggesting that QIPP is not overly sensitive to any one component criterion. The two highest-scoring proteins, both with a QIPP score of 0.89, are extremely different in length (1,138 for the DNA-directed RNA polymerase, beta subunit versus 323 for the DNA-directed RNA polymerase, alpha subunit). When length is removed as a component criterion of QIPP, the scores of the shortest proteins increase by up to 0.16, while those of the very longest proteins decrease by a maximum of 0.09 giving a new mean value of 0.75 (±0.141).
Validation of orphans with low QIPP scores using results from transcriptomic and proteomic studies
To test whether we could validate the expression of orphans with low QIPP scores in a well-studied model organism, we searched the MicrobesOnline database [27] for E.coli K12 orphans identified in this study. This database provides experimental microarray results for this organism for four stress conditions: heat shock [28], pH [29], UV exposure [30] and tryptophan metabolism [31]. We examined the fifty highest and lowest ranked species-level TRGs (N = 100). The scores of the top ranking CDS ranged from 0.41–0.64 and the bottom from 0.02–0.28. To illustrate the range of CDS involved, the top scoring CDS was 547 amino acids in length, zero percent low complexity, average G+C content, but was more costly than average and came from a poorly characterized region of the genome. By contrast, the CDS with the lowest score of 0.02 was only 60 amino acids in length, 35% low complexity, had a highly deviant base composition, it was also more costly than average and was found in a poorly characterized region of the genome. Of these 100 orphans, 17 had identifiers not found in the MicrobesOnline database and were excluded. Of the remaining 83, only one failed to show any change in expression levels in any of these experiments. In total there were 46 occasions (involving 35 of these 100 orphans) when one of these orphans was included in the list of the 200 proteins reported in Microbes Online showing the largest (up or down) fold change in expression in one of these experiments. Of particular interest was the pH stress experiment where 12 (three in the top and nine from the bottom 50) of the top 100 up-regulated genes were orphans (p = 0.00, chi-square).
E.coli K12 proteomic data sets [32]–[34] were also searched. When combined these investigations identified approximately 1,800 expressed proteins. While mRNA was found for 64 of the 174 CDS in E. coli, only 4 proteins could be identified for all 174 single-copy TRGs in this data set. These four CDS had an average QIPP score of 0.32 compared to mean score of 0.35 for all E.coli orphans.
We have developed an index called “QIPP” (“Quality Index for Predicted Proteins”) which can be used to assign a value between zero and one for a CDS compared to the rest of the genome on the basis of a set of selective criteria. This provides an objective measure of the probability that a given CDS either encodes a protein or is an annotation artefact (incorrect). Very long CDS, with typical nucleotide and amino-acid compositions, no low complexity regions, and which are found in well conserved regions have the highest QIPP scores and are considered most likely to encode proteins.
The distributions of QIPP scores, and trends in the component variables, confirm that orphans show consistent differences when compared with well characterised protein-coding genes i.e. they are short, repetitive, possess atypical G+C content, have high average cost for amino acids and are located in poorly characterised regions of the genome. The significant differences in the distributions of QIPP scores between orphan genes and non-orphan genes confirms that QIPP scores represent a valid means to rationalise and automate the identification of those CDS most likely to encode proteins (and find homologues among other available sequences). Because orphans generally have low QIPP scores it is also possible to meaningfully rank them as a subset of all CDS, selectively filter for high-scoring ‘authentic’ orphans, and begin to address the issue of correcting for the high percentage of orphans in current databases that are simply an artefact of sampling bias.
Our data show that the lowest-scoring CDS encode the least evolutionary conserved proteins, i.e. those orphans restricted to single strains or species. As such, this approach can also provide evidence on the likely taxonomic range of a CDS in the absence of any useful homology. This is particularly significant given the unrepresentative sampling of the current genomic databases. Low-scoring, taxonomically restricted orphans are most likely to be annotation artefacts: we tested this in the case of E. coli K12 by reference to online transcriptomic and proteomic expression data. Surprisingly, these data revealed that even these low-scoring CDS are potentially expressed (given the caveats associated with using microarray data to validate orphans [6] and the fact that E. coli is one of the most thoroughly studied organisms) and therefore suggest that annotation artefacts may not be as common as previously suspected. It is clear that empirical validation of genomic annotations is necessary and should be of the highest priority [35]–[37]. At a minimum it would appear premature to dismiss all very low-scoring orphans as having little biological relevance without further evidence.
In effect, the criteria used in the QIPP score reflect the extent of purifying selection acting upon a sequence, which, in the absence of homology, preclude the use of more widely-used methods such as examination of dN/dS ratios [38]. Purifying selection should over time preferentially purge substitutions leading to the use of more metabolically costly amino-acids [39]. Similarly, mutation pressure tends to move in the direction GC->AT rather than vice versa [40], [41] and AT enrichment has commonly been cited as a footprint for relaxed or inefficient purifying selection (but see [42]). This can explain the high AT content of obligate endosymbionts or intracellular parasites which are adapted to a restricted niche, undergo restricted gene exchange, and possibly mutate at a high rate due to the loss of DNA repair genes [43]. It is also well documented that phage and other mobile elements tend to show a higher AT content than the host bacterial genome [5], [39]. As highly conserved proteins are likely to encode essential housekeeping functions, and therefore be subject to high levels of purifying selection, the noted correlation between the taxonomic range and QIPP score can be explained within this selective framework. This phenomenon also provides further validation for the use of the QIPP score in identifying “real” genes, as it is expected that CDS which are simply annotation artefacts should be evolving neutrally and hence have very low QIPP scores.
This analysis provides proof of principal that the combined use of different criteria can be a powerful approach to determining the biological relevance of putative CDS. The power of the QIPP score could be improved by the use of additional criteria which are likely to reflect purifying selection, such as codon bias, for example. It is acknowledged that the criteria presently used are unlikely to be independent, and multivariate analysis is required to determine the interactions between the variables and to put corrections in place to improve the predictive power of the index. Preliminary analysis on five reference genomes has revealed a significant correlation (p< = 0.05) between sequence length and complexity, with longer proteins showing more low complexity regions. Further, a significant correlation between G+C content and amino-acid cost was noted in four out of five genomes (the exception being V. vulnificus; data not shown).
There is a growing need for metrics that offer a deeper understanding of the detailed content of genomes, especially now that we have such large numbers [44]. QIPP provides such a metric and can be used in combination with other in silico methods that can now be used to sift out potentially authentic orphans and improve genomic annotation. Such complementary methods include the analysis and removal of short CDS [6], gene fragments [45], and pseudogenes [8] and the ranking of CDS based on the availability of homology-based information [20]. Integration of the information from such studies would provide the foundation for a single, global list of uncharacterized predicted proteins that could be used to systematically subject them to further in silico examination [20], [35], [37]. This data set could further be integrated with empirical evidence from a range of experimental studies, especially high throughput ‘omic studies, as is the case for databases like STRING [46]. In silico studies of predicted proteins can help identify candidates for further examination, but any validation of the biological relevance of a particular protein must be based on empirical evidence [13], [35], [47], [48]. In order to comply with the principle of the transparent access to data for the sake of integration [49], all of the data generated in this study is available online in a searchable database, the OrphanMine, a database that supports wide-scale downloads of data, including lists of CDS with rich annotations in GFF3 (Generic Feature Format Version 3) (http://song.sourceforge.net/gff3.shtml) format.
In conclusion, the QIPP index supports an objective rationale for prioritising predicted genes for further study, including ‘authentic’ single-copy TRGs. Although further work is required to refine the approach, this represents an important step in the standardisation and automation of identifying biologically important genes in the absence of homology.
Material and Methods
Processing of Genomes and Proteomes
All genomic annotations and proteomes as both amino acid and DNA were downloaded from the NCBI Refseq FTP site. Orphans were detected as previously described [4] using NCBI Blast [50] and a cutoff of 10−3 and then loaded into the OrphanMine database for post-processing. The OrphanMine interface was used to generate groups of TRGs for each taxonomic level. A custom Perl script was used to calculate length, G+C content and cost and to parse blast reports to generate a “neighbourhood distribution” (ND) for each CDS. All of the data used in this study is publicly available through the OrphanMine. The code used to generate lists of orphans from proteomes is available in the YAMAP package (www.genomics.ceh.ac.uk/yamap/) and all other code (any additional Perl scripts) is available on request (gawi@ceh.ac.uk).
Calculation of QIPP scores
For each genome and for each of the five selected criteria, the distribution of non-orphans was generated and the percentiles for that distribution were calculated. For the criteria of length and ND, the absolute value of each component criterion (e.g. length of 200 amino acids) was transformed into a sub-score from 0 to 100 depending on the percentile in which it fell (e.g. the 35th percentile from the shortest CDS found would be given a score of 35). For low complexity and cost, where more of either actually suggests a less probable CDS, the score was subtracted from 100 (e.g. a protein with 50% low complexity might fall in the 70th percentile and therefore be given a low score of 30). G+C content had to be calculated as the deviation from the mean value. Values above the 50th percentile were corrected by the equation 100 minus the percentile value multiplied by two and values below had their percentile doubled.
Length was calculated as the total number of amino acids and percentage low complexity regions was calculated from regions masked with the seg program [21] using default parameters. G+C content was calculated from the proteome as DNA. The average amino acid cost of a sequence was calculated using the relative costs for each amino acid according to the values given in Akashi & Gojobori [23]. Randomized proteomes (i.e. any sequence evolving neutrally) are the most costly as purifying selection appears to select for amino acids that are less metabolically expensive [23]. ND was calculated by determining the level of conservation of the five flanking CDS on either side of a particular CDS. For each of these ten genes, the number of species in which a similar sequence was found was recorded (maximum of 121 for this dataset). Those numbers were then summed, averaged and percentiles generated for the distribution.
The scores from all five criteria are normalized with respect to each particular genome and can therefore be summed. To obtain a final QIPP score between zero and 1, the average is taken and divided by 100. Zero would be the worst possible candidate for a real gene while 1 would be ideal. Using the interface to the OrphanMine it is possible to perform user-selected rankings of subsets of the CDS held in the database on the basis of 1 or all of the component criteria used in QIPP. To compare QIPP and Glimmer scores, the five reference genomes were run through Glimmer (v2.13) [51] with default settings.
Genetic Similarity of genomes and the taxonomic distribution of TRGs
The Index of Isolation of an Organism (IIO) similarity measure was calculated by averaging the logarithm of the best e-value for each CDS in a proteome as described by Fukuchi & Nishikawa [8]. The taxonomic distribution of each CDS in the five references genomes (Table 3) was obtained through interrogation of the OrphanMine database [4]. For each genome, appropriate queries were performed to find genes restricted to each taxonomic level. The output was scored and downloaded in a tab-delimited format. A Perl script was written to parse the output to ensure that every predicted protein was only counted once and each protein could be classed according to its lineage specificity.
Obtaining Empirical Data from Microarray and Proteomic Studies
The MicrobesOnline database [27] was queried for the E.coli orphan genes using their unique VIMSS ID. A file was provided by Keith Keller to map the GenBank IDs of the orphan genes obtained from OrphanMine to the VIMSS ID. EchoBASE is a database that curates information regarding the genes and gene products of the model bacterium E. coli K-12, including links to literature describing proteomic analyses of this bacterium [52]. The ‘b number’ identifiers provided in the literature were used to map data from the proteomic analyses to the E.coli orphan genes obtained from OrphanMine. When ‘b numbers’ were not provided, the gene name, if present, was used.
The number of predicted proteins, orphans, percentage orphans, isolation index and taxonomic uniqueness for each of the 122 bacterial genomes used in this analysis
(0.22 MB DOC)
Figure S1.
Relationship between the numbers of orphans as a percentage of total predicted proteins and Isolation Index of an Organism. The IIO for each genome in our dataset (full list of genomes given in Table S1) is plotted against (a) percentage of orphans, (b) the number of orphans greater than 200 aa's and (c) the percentage of total orphans greater than 200 aa's in length. In addition, each genome is classed according to the taxonomic level at which it is the only sequenced representative.
(3.29 MB TIF)
We thank Andrew Spiers, Rob Edwards, Dave Ussery, Chris Taylor, Peter Sterk, Mike Allen, Anil Wipat, Alice MorningStar, Lisa Crossman, Jack Gilbert and Sarah Turner for critical reading of the manuscript and Keith Keller for mapping of unique identifiers for use in the MicrobesOnline database [27].
Conceived and designed the experiments: EF DF GW. Performed the experiments: GW. Analyzed the data: DF GW. Contributed reagents/materials/analysis tools: GW. Wrote the paper: DF GW. Other: Provided expert statistical input which made the paper possible: AL.
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What’s Coming Near? The Influence of Dynamical Visual Stimuli on Nociceptive Processing
Annick L. De Paepe ,
* E-mail: Annick.DePaepe@Ugent.be
Affiliation Department of Experimental-Clinical and Health Psychology, Ghent University, Ghent, Belgium
Geert Crombez,
Affiliations Department of Experimental-Clinical and Health Psychology, Ghent University, Ghent, Belgium, Centre for Pain Research, University of Bath, Bath, United Kingdom
Valéry Legrain
Affiliation Institute of Neuroscience, Université catholique de Louvain, Brussels Woluwe, Belgium
Annick L. De Paepe,
Annick L. De Paepe Geert Crombez Valéry Legrain
Objects approaching us may pose a threat, and signal the need to initiate defensive behavior. Detecting these objects early is crucial to either avoid the object or prepare for contact most efficiently. This requires the construction of a coherent representation of our body, and the space closely surrounding our body, i.e. the peripersonal space. This study, with 27 healthy volunteers, investigated how the processing of nociceptive stimuli applied to the hand is influenced by dynamical visual stimuli either approaching or receding from the hand. On each trial a visual stimulus was either approaching or receding the participant’s left or right hand. At different temporal delays from the onset of the visual stimulus, a nociceptive stimulus was applied either at the same or the opposite hand, so that it was presented when the visual stimulus was perceived at varying distances from the hand. Participants were asked to respond as fast as possible at which side they perceived a nociceptive stimulus. We found that reaction times were fastest when the visual stimulus appeared near the stimulated hand. Moreover, investigating the influence of the visual stimuli along the continuous spatial range (from near to far) showed that approaching lights had a stronger spatially dependent effect on nociceptive processing, compared to receding lights. These results suggest that the coding of nociceptive information in a peripersonal frame of reference may constitute a safety margin around the body that is designed to protect it from potential physical threat.
Citation: De Paepe AL, Crombez G, Legrain V (2016) What’s Coming Near? The Influence of Dynamical Visual Stimuli on Nociceptive Processing. PLoS ONE 11(5): e0155864. https://doi.org/10.1371/journal.pone.0155864
Editor: Suliann Ben Hamed, Centre de Neuroscience Cognitive, FRANCE
Received: December 10, 2015; Accepted: May 5, 2016; Published: May 25, 2016
Copyright: © 2016 De Paepe et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability: All relevant data are within the paper and its Supporting Information file.
Funding: A.L. De Paepe is supported by the Research Foundation Flanders (FWO, Belgium, http://www.fwo.be). V. Legrain is supported by the Fund for Scientific Research of the French speaking Community of Belgium (F.R.S.-FNRS, http://www.fnrs.be). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Localizing potentially harmful objects approaching our body is essential to adequately defend ourselves [1,2]. This ability requires the construction of a coherent representation of our body, and the space closely surrounding our body, i.e. the peripersonal space. The peripersonal space serves as a multisensory motor interface between our body and the environment [3,4], in which information from the body surface (e.g. tactile or nociceptive stimuli) is integrated with information from the external world (e.g. visual or auditory stimuli). This enables us to interact with the world: we can reach and grasp objects, and we can also avoid objects or defend ourselves against threatening objects intruding our peripersonal space. In monkeys this ability has been found to rely on bimodal visuotactile neurons in the ventral premotor cortex and the ventral intraparietal sulcus [5], which fire both for tactile stimuli and for visual stimuli presented near the stimulated area. Similarly, Dong et al. [6] found neurons in area 7b of the inferior parietal lobe of monkeys, that respond to nociceptive stimuli and to dynamical visual stimuli moving towards the receptive fields of these neurons. Dong et al. [6] suggested that this area provides visuo-somatic information about potentially noxious stimuli, and that it directs motor adjustments so that body exposure and contact with the threatening stimuli is minimized. In humans, a similar system has been proposed for tactile and visual stimuli (for a review, see [7]), and more recently also for nociceptive and visual stimuli [8–12]. However, unlike animal studies, most of the behavioral research in humans has used external (e.g. visual) stimuli at only two fixed locations (i.e. one position near the participants, and one far from the participants), instead of dynamical stimuli. There are several reasons why it could be more interesting to study the influence of dynamical stimuli on nociceptive (and tactile) processing. First, it would increase the ecological validity of the studies, as in real life objects are continuously moving around in the environment. Second, it would make research in humans more comparable to the animal studies mentioned above investigating multisensory integration within the peripersonal space [5,6]. Third, the neural systems representing the peripersonal space show a preference for moving stimuli over static stimuli, both in monkeys and in humans. In monkeys, visual and tactile responses of some of the bimodal neurons in the premotor cortex are directionally specific [13–15]. Moreover, the firing rates of some of these neurons change dynamically with stimulus velocity [14]. Also in humans there is some evidence that approaching visual, auditory and tactile stimuli evoke increased neural activity within the intraparietal sulcus and the ventral premotor cortex [16,17]. Because of the relevance of moving objects to the peripersonal space system, Canzoneri, Magosso, & Serino [18] developed a paradigm enabling to investigate the influence of dynamical auditory stimuli on tactile processing. In this task, Canzoneri et al. [18] measured reaction times (RTs) to a tactile stimulus applied to the right index finger while dynamical sounds, which gave the impression of either approaching or receding from the subject’s hand, were presented. Tactile stimulation was delivered at different temporal delays from the onset of the sound, such that it occurred when the sound source was perceived at varying distances from the body. Participants were asked to respond as fast as possible, trying to ignore the sound. They found that an auditory stimulus speeded up the processing of a tactile stimulus applied to the hand when the sound was administered within a limited distance from the hand. Moreover, results suggested that approaching sounds had a stronger spatially-dependent effect on tactile processing compared to receding sounds.
The ability to quickly localize stimuli on the body and in external space seems especially relevant in the context of pain. Indeed, potentially harmful objects approaching our body have to be quickly localized so that an appropriate defensive response can be prepared. In this study, we adapted the paradigm of Canzoneri et al. [18] to investigate the influence of dynamical visual stimuli on nociceptive processing. A visual stimulus was either approaching or receding the participant’s left or right hand. At different temporal delays from the onset of the visual stimulus, a nociceptive stimulus was applied either at the same or the opposite hand, so that it was presented when the visual stimulus was perceived at varying distances from the hand. Participants were asked to respond as fast as possible at which side they perceived a nociceptive stimulus. We expected that RTs to nociceptive stimuli would progressively decrease as a function of the perceived approach of the visual stimulus. Conversely, we expected RTs to increase as a function of the perceived recession of the visual stimulus. Moreover, we expected that this effect would be larger when visual stimuli were approaching/receding at the side of space in which the stimulated hand resided as opposed to when they were approaching/receding at the opposite side of space. The best fitting curves of the RTs as a function of the perceived position of the visual stimuli in space were studied in order to compare the influence of approaching versus receding visual stimuli on nociceptive processing.
2.1. Participants
30 paid participants volunteered to take part. Three participants (2 males, 1 female) were excluded because they failed to feel the stimulation despite repeated displacement of the electrodes (see section 2.2.). The final sample consisted of 27 participants (26 females, all right handed) with a mean age of 21 years (ranging from 18 to 26 years). All of the participants had normal or corrected-to-normal vision. Recent neurological, psychiatric or chronic pain diseases and usual intake of psychotropic drugs were considered as exclusion criteria. The experimental procedure was approved by the ethics committee of the faculty of psychology and educational sciences of Ghent University (2014/46). All of the participants provided written informed consent prior to taking part in the study.
2.2. Stimuli and apparatus
The nociceptive stimuli were delivered by means of intra-epidermal electrical stimulation (IES) (DS7 Stimulator, Digitimer Ltd, UK), with stainless steel concentric bipolar electrodes (Nihon Kohden, Japan; [19]). The electrodes consisted of a needle cathode (length: 0.1 mm, Ø: 1.4 mm). By gently pressing the device against the participant’s skin, the needle electrode was inserted into the epidermis of the dorsum of the hand in the sensory territory of the superficial branch of the radial nerve. Using intra-epidermal stimulation at maximum twice the absolute detection threshold was shown to selectively activate the free nerve endings of the Aδ fibers [19–21]. The detection threshold was determined with single-pulse stimuli (0.5 ms square wave pulse) using a staircase procedure [22]. The detection threshold was established separately for each hand. Next, the stimulus intensity was set at twice the detection threshold. If necessary, the intensity of the stimuli was adjusted so that the stimuli delivered to each hand were perceived as being equally intense. During the course of the experiment, the stimuli consisted of trains of four consecutive 0.5 ms square-wave pulses separated by a 5-ms inter-pulse interval. Using a set of pain words from the Dutch McGill Pain questionnaire [23] the stimuli were described as pricking. After each experimental block, the participants were asked to estimate the intensity elicited by the nociceptive stimuli on a numeric graphic rating scale (10 cm) with the following labels selected from the Dutch version of the McGill pain questionnaire (Vanderiet at al., 1987): 0 = felt nothing, 2.5 = lightly intense, 5 = moderately intense, 7.5 = very intense, 10 = enormously intense). This scale was used to ensure that: (1) the stimuli were still perceived, and (2) the percept elicited by the IES delivered to each of the participant’s hands was still equivalent. If one of these two criteria was not met, the stimulus intensities were modified (with a maximum intensity of 0.50 mA). If this adaptation proved to be unsuccessful (i.e. if one of the criteria was still not met), the electrodes were displaced and the procedure was restarted.
The visual stimuli were presented by means of fourteen green light-emitting diodes (LEDs), and a red LED for fixation.
The participants sat on a chair in a dimly illuminated, sound-attenuated room, with their head position fixed in a chin rest. The height of the chin rest was individually adapted. Participants rested their arms on the table in front of them, and placed their hands, palm downward on the table. The distance between the participants’ hands and their trunk, as well as the distance between the participants’ index fingers was 40 cm. In total 14 LEDs were positioned at different distances from the hands. 7 LEDs were positioned in the left side of space, and 7 LEDs in the right side of space. At both sides, the first LED was positioned in between thumb and index finger, the next six LEDs were positioned on a straight line one in front of the other with 12 cm in between successive LEDs, so that the last LED was 72 cm in front of the first LED. On each trial, the LEDs on one side were successively illuminated, creating the illusion of a light coming closer towards the participant (if the first LED illuminated was the LED at a distance of 72 cm from the participants), or going further away from the participant (if the first LED illuminated was the LED in between thumb and index finger). Each LED was illuminated for 280 ms, so that the total dynamical visual stimulus had a duration of 1960 ms. A red fixation LED was positioned in between the LEDs in left and right space, 36 cm in front of the first LEDs. This fixation LED was illuminated at the beginning of each trial, and was turned off for 1s at the end of each trial.
2.3. Procedure
The experiment started by illuminating the LEDs one by one. Participants were asked to look at the fixation LED and to indicate verbally at which side of space a light was illuminated (i.e. “left” or “right”). This was done to ensure that participants could see all the LEDs. Next, participants completed a practice phase of 14 trials, in which they executed the experimental task. Participants had to achieve 90% correct performance in this practice phase in order to proceed with the experiment.
Each trial started with the illumination of the fixation LED for 1s. Thereafter the dynamical visual stimulus started. At different temporal delays after the onset of the visual stimulus, a nociceptive stimulus could be presented: T1, a nociceptive stimulus was administered 170 ms from light onset; T2, 450 ms from light onset; T3, 730 ms from light onset; T4, 1010 ms from light onset; T5, 1290 ms from light onset; T6, 1570 ms from light onset; T7, 1850 ms from light onset. This was true both for the approaching and the receding light. That way, the light was perceived at different locations with respect to the body at the moment the nociceptive stimuli were presented. For example, when the light was approaching it appeared close at high temporal delays. Conversely, when the light was receding, it appeared close at low temporal delays (see Fig 1).
Fig 1. Experimental set-up.
At the left side of the figure, a light is approaching the participant at the left side of space. At T1 (170 ms from light onset) the participant gets a nociceptive stimulation to the left hand (congruent to the side of space where the light is presented). At that time, the light is at 72 cm from the participants hand. At the right side of the figure, a similar situation is depicted, however now the light is receding from the participants hand, so that the light is in between the thumb and the index finger at the time of stimulation. Moreover, now the right hand is stimulated (incongruent to the side of space where the light is presented). The dashed arrow indicates the moving direction of the lights.
The experiment consisted of 8 blocks of 56 trials each. The trials were created by crossing the moving direction of visual stimulus (approaching vs. receding) with the side at which the visual stimulus was presented (left vs. right side of space), the congruency of the visual and nociceptive stimulus (congruent vs. incongruent), and the 7 different temporal delays (T1—T7). 1/8 of the trials (i.e. 7 trials) per block were randomly assigned as catch trials, in which no nociceptive stimulus was presented.
Participants were instructed to keep their gaze on the fixation LED during the whole block. They were asked to respond as fast and accurately as possible which hand was stimulated (left or right hand). Responses were given by means of two foot pedals, one positioned beneath the toes, and one beneath their heel. Participants were instructed to keep the foot pedals depressed during the experiment, and to lift either their toes or their heel to respond. Participants were informed that the visual stimulus was unpredictive of the delivery of the subsequent nociceptive target. The experiment took on average 60 minutes to complete.
2.4. Measures
Because participants were highly accurate in performing the task (see section 3.3.), performance was only analyzed in terms of the reaction time (RT). Only RTs from correct trials were considered for analysis. RTs exceeding three times the median absolute deviation (MAD) [24] were considered outliers and were trimmed from the analyses (4% of trials on average over all conditions). Mean RTs were calculated for every temporal delay, for congruent and incongruent trials, and for approaching and receding visual stimuli, creating 28 different conditions.
After the experiment participants were asked to indicate how threatening they thought the visual lights were both when the light was approaching, and when the light was receding, on a scale from 0 (not at all) to 10 (extremely). The perceived threat score was compared for approaching and receding visual stimuli.
2.5. Analyses
Between each block participants were asked to rate the intensity of the stimulation for the left and the right hand on a numeric graphic rating scale (10 cm) with the following labels selected from the Dutch version of the McGill pain questionnaire [23]: 0 = felt nothing, 2.5 = lightly intense, 5 = moderately intense, 7.5 = very intense, 10 = enormously intense. The equivalence of the average current intensity and the average self-reported intensity for the left compared to the right hand was assessed using paired samples t-tests.
The perceived threat score was compared for approaching and receding lights using paired samples t-tests.
Mean accuracies were investigated to check whether any participants performed poorly on the task and therefore had to be excluded. However, accuracies were not of primary interest here, and were therefore not further analyzed.
The reaction time data was analyzed with R software [25] using linear mixed effects models as implemented in the package “lmerTest: tests in linear mixed effect models” [26,27]. Linear mixed effects models account for the correlations in within-subject data by estimating subject-specific deviations (or random effects) from each population-level factor (or fixed factor) of interest (see [28], for an elaboration). The outcome variable of interest was the RT. First all manipulated variables were taken into account, including the side of the stimulation (left versus right hand). However, as this variable did not interact with any of the other variables, it was left out of further analyses to increase power and for the sake of parsimony (see section 3.1.). The independent variables considered in the analysis were the visual stimulus direction (approaching vs. receding lights), the congruency of the nociceptive target (congruent vs. incongruent to the visual stimulus), and the temporal delay (T1 to T7). These were manipulated within subjects. Each analysis required three steps. First, all relevant factors and interactions were entered in the model as fixed factors, and we assessed whether it was necessary to add a random effect for each of the fixed factors in the analysis: If a random effect significantly increased the fit of the model, it was included in the final model. By default, a random effect was added introducing adjustments to the intercept conditional on the Subject variable. In the second step, we searched for the most parsimonious model that fitted the data. To achieve this, we systematically restricted the full model, comparing the goodness of fit using likelihood ratio tests. Finally, in the third step, we inspected the ANOVA table of the final model and tested specific hypotheses about possible main effects or interactions (for a similar approach, see [29–32]). P-values were calculated based on Satterthwaite’s approximations [33]. When an interaction effect was significant, it was further investigated with follow-up contrast analyses. The different steps in the model building procedure are illustrated in the supplementary information (S1 File).
3.1. Intensity of the nociceptive stimulation
The mean current intensities used during the experiment were not significantly different for the left (M = 0.43 mA, SD = 0.05) and the right (M = 0.43 mA, SD = 0.07) hand, t(26) = 0.42, p = 0.68. These values correspond to those used in previous studies that succeeded to selectively activate nociceptors [19,20,34], and are much lower than those used in studies that failed to show selective activation [35].
However, the mean self-reported intensities (numeric graphic rating scale) were significantly lower for the left (M = 2.63, SD = 1.50) than for the right (M = 3.72, SD = 1.77) hand, t(26) = -3.54, p = 0.002. To check whether this difference in self-reported intensities had an effect on task performance, the side of the nociceptive stimulus was added to the model as additional variable. Although the main effect of side (F(1,9394.6) = 65.67; p < 0.001) was significant, indicating slower RTs when the left, compared to the right hand was stimulated, none of the interaction effects of side with any of the other variables (all F < 3.5; p > 0.05) were significant. For the sake of parsimony and to increase power, this variable was left out of further analyses.
In a number of trials participants didn’t feel anything, despite the fact that a stimulation to one of both hands was applied. On average 1% (±3%) of the stimuli was not felt. Two participants did not feel respectively 7% and 12% of the stimuli. However, these participants still had more than 80% correct responses in total, and were thus kept in the analyses (see section 3.3.).
3.2. Perceived threat value visual stimuli
Mean perceived threat scores were overall low, but significantly higher when the lights were approaching (M = 1.78, SD = 2.47) the participants, than when they were receding (M = 0.81, SD = 1.44), t(26) = 3.22, p = 0.003.
3.3. Accuracy
All participants had on average more than 80% correct task performance, and we decided to keep all participants in the analyses. Mean accuracy was 96% (± 4%). Accuracies were not further analyzed.
3.4. Reaction times
The relationship between the RTs to the nociceptive targets, the different temporal delays at which the nociceptive stimuli were administered (from T1 to T7), the visual stimulus direction (approaching vs. receding) and the congruency of the nociceptive stimulation (congruent vs. incongruent to the visual cue) are represented in Fig 2.
Fig 2. Mean RTs to the nociceptive targets and their associated standard errors in function of the different temporal delays at which the nociceptive stimuli were administered (from T1 to T7), the direction of the visual stimulus (approaching vs. receding) and the congruency of the nociceptive stimulation (congruent vs. incongruent to the visual cue).
The linear mixed effects model that demonstrated the best fit with the data, included all fixed factors together with their two-and three-way interactions, a random subject-based intercept, a random trial-based intercept and a random effect for temporal delay and congruency. In this final model, there was a significant main effect of visual stimulus direction (F(1,9414) = 12.04; p < 0.001), a significant main effect of temporal delay (F(6,30.8) = 12.21; p < 0.001), and a significant main effect of congruency (F(1,27.7) = 7.72; p = 0.01). Furthermore, the interaction effect between visual stimulus direction and temporal delay (F(6,9413.9) = 8.95; p < 0.001) and the three-way interaction between visual stimulus direction, congruency, and temporal delay (F(6,9398.4) = 3.76; p < 0.001) were significant. The interaction effect between visual stimulus direction and congruency (F(1,9381.7) = 2.30; p = 0.13) and between congruency and temporal delay (F(6,9385.5) = 1.51; p = 0.17) were not significant.
To further investigate the three-way interaction, two separate linear mixed effects models were fitted for congruent and incongruent trials with visual stimulus direction and temporal delay as independent variables and RT as dependent variable.
For congruent trials, the model that demonstrated the best fit with the data included the fixed factors and their interaction, a random subject-based intercept, a random trial-based intercept and a random effect for temporal delay. In this model, there was a main effect of visual stimulus direction (F(1,4642.7) = 11.85; p < 0.001), a main effect of temporal delay (F(6,29.7) = 14.88; p < 0.001), and an interaction effect between visual stimulus direction and temporal delay (F(6,4634.4) = 10.48; p < 0.001). Follow-up tests indicated that at T1, RTs were significantly slower for approaching than for receding visual stimuli (χ2(1) = 27.03, p < 0.001). This effect reversed at T3, T4, T5 and T7, where reaction times were significantly slower for receding than for approaching visual stimuli (T3: χ2(1) = 19.14, p < 0.001; T4: χ2(1) = 10.49, p = 0.001; T5: χ2(1) = 9.77, p = 0.002; T7: χ2(1) = 7.72, p = 0.005). At T2 and T6 reaction times did not differ significantly between approaching versus receding visual stimuli (T2: χ2(1) = 0.03, p = 0.86; T6: χ2(1) = 0.42, p = 0.52).
For incongruent trials, the final model consisted of all fixed factors, and their interaction, a random subject-based intercept, and a random effect for visual stimulus direction and temporal delay. In this model there was a main effect of temporal delay (F(6,28.1) = 8.32; p < 0.001), and a significant interaction effect between visual stimulus direction and temporal delay (F(6,4646.1) = 2.39; p = 0.03). The main effect of visual stimulus direction was not significant (F(1,27.3) = 1.14; p = 0.30). Follow-up tests indicated that at T2, RTs were marginally significantly faster for receding than for approaching trials (χ2(1) = 3.28, p = 0.07). Conversely, at T7, RTs were significantly faster for approaching than for receding trials (χ2(1) = 7.15, p = 0.008). None of the other comparisons were significant (all χ2 < 1.6; all p > 0.20).
Because the difference between receding and approaching trials for incongruent trials was only present at two time points and thus proved to be less consistent, further analyses focused on congruent trials. Pairwise comparisons between the different temporal delays for approaching visual stimuli showed that RTs at T1 were significantly slower than at any other temporal delay (all |t| > 5.00; all p < 0.001); RTs at T2 were significantly slower than reaction times at T3 to T7 (all |t| > 1.5; all p < 0.05); RTs at T3 were significantly slower than RTs at T6 and T7 (all |t| > 1.5; p < 0.05); RTs at T4 were marginally significantly slower than RTs at T6 (t(26) = -1.61; p = 0.06) and significantly slower than RTs at T7 (t(26) = -2.54; p = 0.009); finally RTs at T5 were marginally significantly slower than at T7 (t(26) = -1.70; p = 0.05). This provides an indication that for approaching visual stimuli, reaction times overall decreased. Moreover, this decrease was stronger for small temporal delays than for larger temporal delays. For receding visual stimuli, RTs remained stable at small temporal delays, and only dropped at T6 and T7. This is shown by a significant difference between RTs at T1 to T4 versus RTs at T6 and T7 (all |t| > 2.00; all p < 0.006), while RTs in either group did not differ significantly from each other (all |t| < 1.5; all p > 0.05). RTs at T5 were somewhere in between the two groups, as RTs at T5 did not differ significantly from RTs at T1, T2, T4 and T7 (all |t| < 1.5; all p > 0.05), but participants reacted significantly faster at T5 than at T3 (t(26) = -1.84; p = 0.04), and significantly slower at T5 than at T6 (t(26) = -3.20; p = 0.002).
Finally, we evaluated whether the model for congruent trials could be further simplified by considering temporal delay as a continuous variable instead of a factor, so that T1 corresponds to 170 ms, T2 to 450 ms, T3 to 730 ms, T4 to 1010 ms, T5 to 1290 ms, T6 to 1570 ms and T7 to 1850 ms. The nature of the relationship between the independent variable temporal delay and the dependent variable RT was investigated by fitting models with RT as dependent variable and temporal delay as independent variable separately for approaching and receding visual stimuli. At each time the restricted models (with temporal delay as continuous variable) were compared with the full model (with temporal delay as categorical variable). For approaching visual stimuli a linear relationship was first considered, assuming a constant decrease/increase of RT a as a function of temporal delay. This model fitted significantly worse than the model with temporal delay as a categorical predictor (χ2(5) = 35.30, p < 0.001). Next, a quadratic relationship was considered by adding the square of the independent variable temporal delay to the model. This model still fitted the data significantly worse than the full model (χ2(4) = 11.69, p = 0.02). Next, a cubic relationship was considered, and this model did not fit the data significantly worse than the full model (χ2(3) = 2.97, p = 0.40). For receding visual stimuli, the same strategy was applied. Again, the linear (χ2(5) = 19.79, p = 0.001) and the quadratic model (χ2(4) = 15.36, p = 0.004) fitted significantly poorer than the model with the categorical predictor. Now, also the cubic model fitted the data significantly worse (χ2(3) = 11.37, p = 0.01). Finally, a quartic model did not fit the data significantly worse (χ2(2) = 2.03; p = 0.36). The fitted curves are shown in Fig 3. The slopes of the tangent lines evaluated at each of the seven time points was calculated for the fitted curves for approaching and receding visual stimuli (see Table 1). For approaching visual stimuli, RTs decreased strongly at low temporal delays (T1 and T2), and remained more stable at higher temporal delays. For receding visual stimuli, RTs remain stable at low temporal delays (and even increased a little bit), to decrease only at higher temporal delays (from T5 onwards).
Fig 3. Mean RTs and fitted curves for the relationship between temporal delay and reaction time (RT) for congruent trials.
For approaching visual stimuli a cubic model fitted the data best. For receding visual stimuli, a quartic model was used to describe the data.
Table 1. Slopes of the tangent lines evaluated at the 7 time points.
This study investigated the influence of dynamical visual stimuli on nociceptive processing. Results showed that visual stimuli presented near the stimulated hand influenced nociceptive processing more than visual stimuli presented far from the hand, providing evidence for a body-part centered peripersonal frame of reference for the processing of nociceptive stimuli. Moreover, by using dynamical visual stimuli we were able to investigate the influence of visual stimuli along a continuous spatial range (from near to far space) both for approaching and receding stimuli.
To adequately defend ourselves against potential threats we need to be able to construct a coherent representation of our body and the space closely surrounding our body (i.e. the peripersonal space). Within this space the location of somatosensory stimuli, the location of visual stimuli close to the body and information about body posture are integrated [7,36,37]. In monkeys this ability depends on neurons with multimodal receptive fields (RFs), found mainly in the premotor and intraparietal areas [13,38]. These neurons are activated in response to both tactile stimuli and to visual stimuli occurring close to the stimulated body parts. In humans, the use of a peripersonal frame of reference for the localization of somatosensory stimuli has been demonstrated in neuropsychological studies with patients suffering from crossmodal extinction after a right hemisphere stroke. These patients can feel a tactile stimulation to their left hand in isolation, but when the right hand is concurrently stimulated (unimodal extinction) or when a right visual stimulus was presented near the right hand (crossmodal extinction) patients fail to report the left hand stimulation. However, when the right visual stimulus was presented far from the patients’ hand, the degree of extinction was reduced [39,40]. These results are in agreement with the electrophysiological findings from monkeys suggesting that the representation of peripersonal space is body-part centered [13]. Behavioral studies with healthy volunteers using a crossmodal congruency task [41–44] (for a review see [7]) found similar results.
Research investigating whether nociceptive stimuli are also mapped in a peripersonal frame of reference is more scarce. Dong et al. [6] found neurons in area 7b of monkeys that responded both to nociceptive stimuli and to visual stimuli approaching the receptive field of these neurons, especially when these visual stimuli were threatening or novel. Recently, we suggested the existence of a peripersonal frame of reference for mapping nociceptive stimuli in humans using temporal order judgment (TOJ) tasks [8,9]. In these tasks participants received two nociceptive stimulations, one to each hand, with different stimulus onset asynchronies (SOA’s) between both hands. Slightly before the first nociceptive stimulation a visual cue stimulus was presented either in the left or the right side of space, and either near or far from the participants’ hand. We found that visual stimuli presented near the stimulated hand facilitated processing of the nociceptive stimuli applied to that hand. Conversely, visual stimuli presented far from the hand only influenced nociceptive processing to a lesser extent [8,9]. In the current study we were able to replicate these findings showing that when the visual stimuli were presented at the side of space of the stimulated hand, reaction times at T1 were significantly faster for receding visual stimuli than for approaching visual stimuli. This can only be due to the fact that at this temporal delay, the visual stimulus was presented near the participants’ hand for receding visual stimuli, but far from the hand for approaching visual stimuli. This indicates that nociceptive processing was mostly facilitated when a visual stimulus was presented near as compared to far from the stimulated hand. This difference between approaching and receding visual stimuli at T1 was not significant when the visual stimuli were presented at the opposite side of space of the stimulated hand, indicating that it is especially the proximity to the stimulated body part and not so much to the body as a whole that is important. Taken together these results confirm previous findings with a different paradigm, and provide evidence for a peripersonal frame of reference centered on the stimulated body-part for the localization of nociceptive stimuli.
An important new aspect of the present study was the use of dynamical visual stimuli instead of static stimuli at two fixed positions (one near, one far) used in most previous studies. The use of moving stimuli is more ecologically valid and more comparable to animal studies investigating multimodal integration in the peripersonal space [5,6]. Furthermore studies in both humans and monkeys [13–17] have shown that the neural systems representing the peripersonal space show a preference for moving stimuli. By using dynamical visual stimuli, we were able to investigate multisensory integration along a continuum between near and far space. This was done by searching the best fitting function for the relationship between the RTs and the temporal delay at which the nociceptive stimuli were presented. This was only investigated for congruent trials, because the visual stimulus direction (approaching versus receding) most clearly affected the RTs for these trials, indicating that the distance of the visual stimuli to the body had a larger influence on RTs for congruent than for incongruent trials. For approaching trials a cubic function adequately described the data, indicating that RTs did not decrease linearly as a function of the approaching light. Indeed, the RTs dropped strongly in the beginning (T1 and T2), and decreased more slowly at higher temporal delays. This is also shown by the fact that RTs at low temporal delays (T1 and T2) were significantly higher than reaction times to nociceptive stimuli presented at higher temporal delays. For receding trials, a quartic function fitted the data well, indicating that reaction times did not increase/decrease linearly with the receding light. For these trials reaction times remained stable (and slightly increased) at low temporal delays, and then slowly decreased at higher temporal delays. It is surprising that despite the fact that the lights receded from the hand, reaction times nevertheless decreased at higher temporal delays (when the light was far away from the hand). Previous studies using a similar paradigm [18,45,46] also did not find the expected increase in RTs when stimuli were receding. However, in these studies RTs did not decrease at high temporal delays, but remained stable. It is important to note that there are some differences between these studies and the present study. First, these studies used auditory stimuli and tactile targets [18,45], or visual stimuli and tactile targets [46], instead of the visual stimuli and nociceptive targets used in the present study. Next, in the present study both the left or the right hand could be stimulated and the lights were approaching/receding at the same or the opposite side of space. Participants had to indicate which hand was stimulated (localization task). The previous studies only stimulated the right hand [18] or cheek [45] and participants had to indicate whether they felt a stimulation (detection task). Furthermore, Canzoneri et al. [18] and Serino et al. [46] also used ‘unimodal’ stimuli, i.e. tactile stimuli could occur during a silence period, preceding or following sound/visual stimulus administration. Serino et al. [46] used these unimodal trials as a baseline. Subtracting the fastest unimodal tactile condition from the bimodal conditions, gives a measure of the facilitation effect, due to the bimodal stimulation. They assessed the modulation of the facilitation effect in function of the temporal delay, instead of the raw RTs. An additional advantage of using unimodal trials is that it partly controls for spurious modulations of RTs due to an expectancy effect. Moreover, it controls for between-subject differences in RTs to tactile stimuli. Relatedly, Canzoneri et al. [18] and Teneggi et al. [45] had more catch trials (respectively 40% and ~33% out of the total amount of trials, compared to 12.5% in the present study). These catch trials should ensure that the expectation to receive a nociceptive stimulation to one of the hands does not increase with higher temporal delays. In the present study, catch trials were presented in 1/8 of the trials in each block. Given that no unimodal trials were used in the present experiment, it could be that the amount of catch trials was not sufficient to avoid the fact that people expected to get a stimulation, and that this expectation increased as the trial proceeded. We chose to eliminate the unimodal trials and to decrease the amount of catch trials to limit the overall amount of trials (and therefore the duration of the experiment) to ensure that participants could remain concentrated until the very end. These differences can be the cause of the decrease in RTs for receding stimuli. However despite this general effect of temporal delay, we were able to find a differential effect of visual stimulus direction (approaching vs. receding) on RTs, indicating that over and above the general decrease in reaction times with time, the direction of the lights significantly influenced RTs.
In accordance with the results of Canzoneri et al. [18] and Serino et al. [46] in the context of touch, our results suggest that the approaching lights had a stronger spatially dependent effect on nociceptive processing, compared to the receding lights. Indeed, the cubic function describing the relationship between RTs and the temporal delay at which nociceptive stimuli were delivered, showed a steep decrease immediately after the onset of the visual stimuli. Conversely, for the receding lights no such steep increase/decrease was present. In fact, reaction times remained stable and only decreased in the end, which is, as argued above, probably due to an increasing expectation of receiving a stimulation. These results are in agreement with studies in primates and humans showing adaptive avoidance responses to both real and simulated approaching stimuli [47–49]. For example, a rapidly expanding shadow elicits fear responses in rhesus monkeys [48] and human infants [50], but rapidly contracting shadows do not. Similarly, in the present study, participants rated the approaching stimuli as more threatening than the receding stimuli, albeit that the overall level of fear was low. Bimodal neurons in the ventral premotor cortex and the posterior parietal cortex of monkeys respond preferentially to approaching visual stimuli [51–53]. Moreover, Cooke and Graziano [4,54] found that when the monkeys’ brain regions that respond to approaching or nearby objects are stimulated, the animal executes defensive movements like withdrawing or blocking. At a behavioral level, humans process tactile stimuli applied to the cheek more rapidly when an object approached the cheek or the region closely surrounding the cheek, but not when this object was receding from the cheek [55]. These results can be explained by the fact that objects approaching us may pose a threat, and signal the need to initiate defensive behavior. Detecting these objects early is therefore crucial to either avoid the object, or prepare for contact most efficiently. In accordance with these results, Cléry et al. [56] demonstrated that tactile processing on the face can be enhanced by looming visual stimuli. More specifically, tactile processing was most enhanced when the tactile stimulus was applied at the expected time and location of impact of the looming visual stimulus. Therefore, the cortical network involved in the construction of the peripersonal space would play a key role in predicting the impact of a stimulus on our body [56]. Serino et al. [46] suggested that the degree of preference for approaching stimuli might vary for different body parts. These authors found that tactile detection on the hand was affected both by approaching and receding sounds, although receding stimuli had a less defined spatial gradient. Conversely, tactile detection applied to the trunk and the face was only affected by approaching sounds, and not by receding sounds. Moreover, comparing the boundaries of the peripersonal space around the hand, the face and the trunk, showed that the boundaries were smallest for the peri-hand space, intermediate for the peri-face space, and largest for the peri-trunk space. These findings are compatible with the function of the peripersonal space as a multisensory-motor interface for body-object interaction, either to plan an approaching movement, or to react to potential threats. Different body parts interact with objects over different portions of space: hand-object interactions occur within a limited space around the arm [57], face-object interactions mainly occur in the context of bringing an object to your mouth within the upper space [58], while trunk-object interactions materialize in a larger portion of space and are related to whole-body actions, such as walking [59]. Moreover, the hand usually receives touches both from approaching and receding stimuli, whereas it is much more likely that face or trunk tactile stimulation originates from an approaching stimulus. These studies suggest that the peripersonal frame of reference may constitute a safety margin around the body that is designed to protect it from potential physical threat and that represents a mechanism for preserving homeostatic control over the body [60,61]. Recently, it has been suggested that the peripersonal space representation cannot only be shaped by actions, but can also be modulated by emotional and social information (for a review, see [62]).
Neuroimaging studies have demonstrated that fronto-parietal brain regions, homologous to the brain regions hosting bimodal neurons in non-human primates, play an important role in the construction of a multimodal representation of the peripersonal space for tactile stimuli [17,63]. Based on the present study, it is reasonable to hypothesize that premotor and parietal areas also play an important role in nociceptive processing and pain perception [64]. Nociceptive inputs activate a large array of cortical areas, such as mainly opercular-insular and cingulated areas, but also frontal and parietal areas [65]. Recently, it was postulated that these areas are not specifically involved in nociceptive processing. Instead, activity in these areas would reflect the detection, localization and reaction to sensory events that are meaningful for the integrity of the body [64]. Based on the present and previous studies [8,9] it can be suggested that the involvement of frontal and parietal areas in nociceptive processing may serve the integration of nociceptive information into a multisensory representation of the body and the space closely surrounding the body.
This study has some limitations. First, the use of dynamical visual stimuli increased the ecological validity of this study. However, one could question the generalizability of a standardized experimental situation to real life. Indeed, it could be interesting to investigate the effect of real life objects (e.g. a syringe or a needle) approaching (or receding) from participants, as has been done in some animal studies (e.g. [6]) and recently also in humans [66,67]. For example, Rossetti et al. [67] investigated the skin conductance response (SCR) to a noxious stimulus (i.e. a needle) approaching and touching the hand, or stopping at different distances (near or far) from the hand. They found that anticipatory responses to an incoming threat were reduced when the stimulus targets a spatial position far away from the body, as compared to a near or bodily location. Despite the larger ecological validity of the use of real life objects, the use of standardized visual stimuli enabled us to investigate the influence of visual stimuli on nociceptive processing along a spatial continuum from near to far space, which would have been much more difficult to investigate in less standardized situations. Second, despite the procedure used to match the intensities of the nociceptive stimuli applied to both hands, the strict equivalence in subjective perception of the intensities between the two hands could not always be achieved. However, these differences were rather marginal (2.63 to 3.72 cm on a rating scale of 10 cm), and analyses showed that the side of stimulation did not affect the RTs. Finally, as mentioned above, we found a general effect of the temporal delay at which nociceptive stimuli were applied, which is most likely due to an increasing expectation to receive a nociceptive stimulus with time. Future studies could possibly avoid this by adding more trials without nociceptive stimulation (i.e. catch trials).
In conclusion, the present study provides evidence for the mapping of nociceptive stimuli in a peripersonal frame of reference. This guarantees a swift and efficient localization of threatening objects by integrating nociceptive information with visual information presented near the stimulated body part, enabling the preparation of a defensive motor response towards the location of threat. Moreover, by using dynamical visual stimuli we were able to investigate the relationship between nociceptive processing and the position of visual stimuli along a spatial continuum from near to far space. For approaching visual stimuli this relationship is best described by a cubic function, meaning that reaction times sharply decrease quickly after the onset of the visual stimulus. Conversely, for receding stimuli, no such sharp increase or decrease was found. This indicates that people are sensitive to the direction of visual stimuli, with approaching objects influencing nociceptive processing more profoundly than receding objects.
S1 File. Model building procedure of linear mixed effect models.
Conceived and designed the experiments: ALDP GC VL. Performed the experiments: ALDP. Analyzed the data: ALDP. Contributed reagents/materials/analysis tools: ALDP. Wrote the paper: ALDP GC VL.
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Is the Subject Area "Vision" applicable to this article?
Is the Subject Area "Reaction time" applicable to this article?
Is the Subject Area "Hands" applicable to this article?
Is the Subject Area "Light-emitting diodes" applicable to this article?
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LesBowen.com
Lake Chelan Mirror
Hospital CEO dismissal
February 10, 2010 lesbowen
Hospital letter outlines board’s findings against former CEO
By Les Bowen for Lake Chelan Mirror | Oct. 21, 2009 | Original source behind paywall
Documents released last week show the build-up in disputes between former CEO Dave Bernier and the hospital district’s board of directors.
Bernier was fired Sept. 14 after more than two months on administrative leave. Last week, the Lake Chelan Mirror obtained a copy of the letter terminating Bernier’s employment dated Sept. 17. The letter cites several instances which the board said it considered dishonest, fraudulent or had a negative impact on the hospital district.
“The hospital did certainly not do their homework and there are a lot of allegations in the letter,” Bernier said in an interview Friday. “They are not facts.”
The former CEO disputed the allegations against him.
“We are proceeding with a tort claim and the issues that are identified in the termination letter are subordinate to our claim,” Bernier said. “There is going to be a discrimination claim.”
Both in an interview and in court papers, Bernier offered an alternative perspective to the board’s view.
“They did not give me an opportunity to correct the issues,” Bernier told the Mirror.
He said the board’s disciplinary actions came as a surprise to him and that he had successfully completed his annual evaluation in February.
“Across the board, the commissioners graded me excellent or outstanding,” he said.
The termination letter tells a different story. Bernier received a housing stipend for housing costs in Chelan that was supposed to terminate once he sold his Ft. Lauderdale, Fla., home.
“We discovered that you discontinued making payments on your condominium in Ft. Lauderdale on June 1, 2008,” the letter states. Bernier claims he was never been properly served with foreclosure documents, even though an affidavit from the process server states otherwise. the former CEO said most of the foreclosure documents bear Florida addresses and just one shows up with a Washington address.
“There is no way I could know that the condo would foreclose when it did,” Bernier told the Mirror.
But putting those issues aside, the former CEO went back to what he sees as a bigger issue – that the funds that were provided to offset the cost of living in Chelan.
That’s reflected in papers filed in Chelan Superior Court, where Bernier said the housing stipend was provided to “help cover the high cost of living in Chelan. It was not given to cover my Florida Mortgages.”
The board’s letter to Bernier also alleges he misrepresented the board’s position related to his housing stipend by attempting to make it a permanent increase to his compensation. The board alleges he altered the agenda and minutes from the Feb. 17 commissioners’ meeting. Both are allegations, the former CEO disputes.
He said when he’s asked for records that would help clear his name, he’s been rebuffed by the hospital. Bernier said his inability to access records, either in his office or retained by the hospital, has hampered his ability to respond to the allegations against him.
The hospital also claims there are several issues related to reimbursements.
One relates to moving expenses. The board initially approved reimbursement of up to $10,000 of Bernier’s moving expenses, but ended up paying out more than $14,000.
“As of June 2009, the hospital was still being contacted by the moving company regarding a past due amount for moving expenses,” states the termination letter, “and although you had received full reimbursement in excess of your contracted amount, you were making monthly payments to the moving company.”
This board considered Bernier’s actions as dishonest and possible theft of property.
Bernier explained in court documents that there is an ongoing dispute with the moving company about charges and he has refused to pay the full amount.
“I did not keep travel reimbursements for my own gain,” he said.
In addition, there are issues related to the hospital’s credit card, which the board claims Bernier used for personal purchases, but never reimbursed. Purchases cited include payment for a hotel room at a conference.
“You acknowledge taking your significant other and his mother to the conference, but have not identified why you needed such an expensive room, nor did you provide explanations for meal charges that far exceed the per diem allowed under hospital policy and clearly indicate you paid for meals for others staying in your room,” the termination letter states.
But Bernier said he always itemized his expenses and reimbursed the hospital for any personal expenses However, his inability to access his personal records in his office a the hospital has prevented him from doing so.
“I plan to itemize travel expenses and reimburse LCCH for the credit card charges they allege were wrongful, once I have the opportunity to access my records,” he stated.
The hospital board also alleges Bernier participated in a golf tournament at the hospital’s expense along with two commissioners, even though he was told “this is not the type of event the hospital could pay for.”
The termination letter goes on to explain that Bernier received personal checks from the two commissioners to cover their fees but never reimbursed the hospital.
Bernier disputes the claim, stating he paid the golf tournament fees back to the hospital, even providing the check number.
A final issue raised by the board relates to references listed at the time Bernier applied for the CEO position. The hospital’s letter claims that one of the individuals was Bernier’s partner – who Bernier requested not be named – and that the former CEO did not disclose that he had both a personal and professional relationship with him.
“After you were hired by the hospital, you let everyone know that you had been in a committed relationship with (him) for over three years,” the letter states.
Bernier’s explanation is that he listed his references in chronological order.
“As it happens, I now have a personal relationship with (him),” Bernier stated in court documents, “but that is not why I listed him as a reference.”
Two more issues were raised by the board, but the details were redacted from the documents. According to court proceedings last Friday, where the documents were discussed, the issues relate to allegations of criminal charges in Klickitat County and a sexual harassment claim at Lake Chelan Community Hospital.
Portions of board’s termination letter to the Bernier and his responses filed in court have not been released.
Regarding the criminal case, a clerk at the Klickitat County courthouse in Goldendale confirmed that the case relates to a misdemeanor-level cyberstalking charge.
Bernier hasn’t see the details of the allegations against him Klickitat County.
“I can’t comment on something I really don’t know about,” he said.
In his interview, Bernier added that since he was placed on administrative leave, he hasn’t been asked a single question.
“I have been prohibited from talking to the staff and commissioners,” he said. That’s something he considers inappropriate, as “anyone should be able to talk to their elected officials.”
However, it appears there has been some contact regarding the matters addressed in the termination letter.
In the opening paragraph, the board’s letter states, “Pursuant to the agreement, you were provided notice of the possible reasons for potential termination in a letter to you through your attorney dated Aug. 7, 2009 and you were provided an opportunity to respond to those reasons in Wednesday, Aug. 12, 2009 in executive session. The board considered your response as well as other information provided by legal counsel in coming to its conclusion.”
The full text of the termination letter, court documents and other related records can be found on the Mirror’s at lakechelanmirror.com.
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Report: 1,000+ illegal immigrants released at Obama’s ‘discretion’ have since committed crimes
By Kenric Ward February 3, 2015 February 3, 2015
More than 1,000 illegal immigrants released under federal “prosecutorial discretion” went on to commit a string of new crimes across the United States, according to Department of Homeland Security records. And that was in just one year. The 38-page DHS report lists the new convictions for fiscal 2013, the latest year for which statistics were available. They include:
—Assault with a deadly weapon
—Lewd acts with a child under 14
—Criminal street gang
—Rape spouse by force
—Child cruelty: possible injury/death
Said Iowa Republican Sen. Chuck Grassley, who chairs the Senate Judiciary Committee:
The Obama administration claims it is using ‘prosecutorial discretion’ to prioritize the removal of criminal aliens from this country. But this report shows the disturbing truth: 1,000 undocumented aliens previously convicted of crimes, and released by the administration in 2013, have gone on to commit further crimes in our communities.
I will continue my work to ensure our immigration officials are doing what it takes to take criminal aliens off our streets and out of our country.
Officials at U.S. Immigration and Customs Enforcement have complained about lack of bed space to house criminal immigrants. According to a Government Accountability Office report, the cost of detaining criminal aliens from 2005 to 2009 was estimated at $1.6 billion annually.
“Given the increase in undocumented immigrants, the current costs may be higher,” Judiciary Committee press secretary Taylor Foy said. “That also does not take into account the cost of releasing criminal aliens into supervised release programs.”
Instead of deporting criminal immigrants, Justice Department attorneys have turned them loose under the Obama administration’s controversial policy of prosecutorial discretion. The resulting public endangerment and strain on local law enforcement agencies sparked an outcry from immigration-enforcement groups Monday.
Jessica Vaughn, director of policy studies at the Center for Immigration Studies, told yours truly:
This report confirms what many of us feared, and what ICE officers know, namely that policies that lead to the release of criminal aliens back into our communities undermines public safety and is creating needless new victims.
These offenders should be sent home, not allowed to stay here.
The president is constantly claiming that his policies allow ICE officers to focus on ‘felons, not families.’ In fact, they prevent ICE officers from dealing with felons, and the criminal aliens who will become felons.
Vaughn cited a recent example of an illegal immigrant arrested last month in the murder of a 21-year-old Mesa, Arizona, convenience store worker over a pack of cigarettes. “[Apolinar Altamirano] is one of the 36,000 who were freed by ICE in 2013. He was a convicted felon when ICE released him in 2013, but ICE officers have been told to release such offenders — without supervision.”
Bob Dane, spokesman for the Federation for American Immigration Reform, said, “Statistics say that one in six criminal illegal aliens who get released get rearrested. Catch and release is good practice for fishing, but not a good one for law enforcement.”
Vaughn said Congress can stop the White House’s criminal merry-go-round.
“Congress has the opportunity to end the Obama administration’s reckless ‘prosecutorial discretion’ policies by passing the DHS appropriations bills with riders that halt the president’s executive actions,” she said.
Read more by Kenric Ward at Watchdog.com.
Posted in: Law and Government, National Security, PoliticsTagged: amnesty, Department of Homeland Security, deportation, Justice Department, Law enforcement, Obama Administration
Kenric Ward
Kenric Ward is a national correspondent and writes for the Texas Bureau of Watchdog.org. Formerly a reporter and editor at two Pulitzer Prize-winning newspapers, Kenric has won dozens of state and national news awards for investigative articles. His most recent book is “Saints in Babylon: Mormons and Las Vegas.”
What’s wrong with Charles Blow’s proposal for ‘desegregating’ jobs in science? A better question is what isn’t?
Cartoon of the Day: On the road again
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Y. Song
JCHS - Joint IASLC - Chinese Society for Clinical Oncology - Chinese Alliance Against Lung Cancer Session (ID 239)
Event: WCLC 2015
Type: Joint Chinese/ English Session
Track: Other
Presentations: 1
Moderators:C. Bai, Y. Wu
Coordinates: 9/06/2015, 07:30 - 10:30, Mile High Ballroom 1a-1f
JCHS.07 - First-Line Icotinib Versus Cisplatine/Pemetrexed plus Pemetrexed Maintenance in Advanced NSCLC Patients with EGFR Mutation (ID 3524)
07:30 - 10:30 | Author(s): Y. Song
Clinical studies with anti-EGFR agents demonstrate that EGFR TKIs play critical roles in the treatment of non-small cell lung cancer, especially in patients with positive EGFR mutation. Icotinib is an oral, selective EGFR TKIs. Phase 3 study showed that icotinib is non-inferior to gefitinib in treating unselected or EGFR-mutated advanced NSCLC patients as second-line therapy but better safety profile, which provide a rationale to examine icotinib in first-line setting. The objective of this study is to evaluate progression-free survival (PFS), overall survival (OS) and safety of icotinib in chemotherapy naïve NSCLC patients with EGFR mutation.
In this phase 3, open-label, randomized study (CONVINCE, NCT01719536), 285 patients (pathologically confirmed NSCLC, positive 19/21 EGFR mutation, treatment naive) will be 1:1 randomized to receive oral icotinib (125 mg, three times daily) or cisplatine (intravenous [IV], 75 mg/m2, day 1) plus pemetrexed (IV, 500 mg/m2, day 1), patients achieving disease control after 4-cycle chemotherapy continue to receive single pemetrexed (IV, 500 mg/m2, day 1) as maintenance therapy until progression. Randomization will be stratified by performance status (0-1/2), smoking status (smoker/non-smoker), disease stage (IIIB/IV), and mutation type (19/21). A total of 228 events would provide 90% power to detect an HR for PFS of 1 at 2-sided significance level of 0.05. Response will be reviewed by both investigator and independent data monitoring committee. Patient enrollment was completed in June 2014, and the results are expected in June, 2015.
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MINI 23 - Lung Cancer Risk: Genetic Susceptibility and Airway Biology (ID 135)
Type: Mini Oral
Track: Screening and Early Detection
Moderators:P.E. Postmus, R. Young
Coordinates: 9/08/2015, 16:45 - 18:15, 401-404
MINI23.14 - Circulating Long Non-Coding RNA GAS5 Is a Novel Biomarkers for the Diagnosis of Non-Small Cell Lung Cancer (ID 2315)
Long non-coding RNAs (lncRNAs) are new-founding RNAs which could regulate many biological processes. Our previous study shown that lncRNA-GAS5 was decreased in lung cancer tissue, which contributed to the proliferation and apoptosis of non-small lung cancer (NSCLC). GAS5 was also associated with the prognosis of lung cancer patients. However, the plasma samples were more easily available than the tissue sample in the clinic. And the expression of GAS5 in the plasma of NSCLC patients was unknown.
90 patients with NSCLC and 33 health controls were included in our study. Blood samples were collected before surgery and therapy. We extracted the free RNA in the plasma and analyzed the expression of GAS5 with quantitative reverse transcription polymerase chain reaction (qRT-PCR). Suitable statistics methods were used to compare the plasma GAS5 levels between the NSCLC patients and health controls, preoperative and postoperative plasma samples. Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic sensitivity and specificity of plasma GAS5 in NSCLC.
The 2[-][△][CT ]of GAS5 in the plasma of NSCLC patients and health controls are 1.053774 and 3.019817, respectively. GAS5 in NSCLC plasma was down-regulated compared with health controls (P=0.001), which was significantly correlated with TMN stage (P=0.024). Furthermore, plasma GAS5 increased markedly on day 7 after surgery compared with preoperative levels in NSCLC patients (P=0.003). The CT values of preoperative and postoperative are 2.225909 and 1.050455, respectively. The area under the ROC curve of GAS5 was up to 0.832. The combination of the GAS5 and CEA could produce 0.909 area under the ROC curve in distinguishing NSCLC patients from control subjects (95% CI 0.857–0.962,p=0.000).These results indicated that lncRNA GAS5 may be a more precise biomarker in NSCLC.
We have demonstrated that GAS5 was decreased in NSCLC plasma expression and the plasma samples were more easily available than the tissue sample in the clinic. So GAS5 could be ideal biomarkers for the early diagnosis of NSCLC.
ORAL 17 - EGFR Mutant Lung Cancer (ID 116)
Type: Oral Session
Track: Treatment of Advanced Diseases - NSCLC
Moderators:P. Meldgaard, E. Felip
Coordinates: 9/08/2015, 10:45 - 12:15, Four Seasons Ballroom F3+F4
ORAL17.01 - First-Line Icotinib Versus Cisplatine/Pemetrexed Plus Pemetrexed Maintenance in Advanced NSCLC Patients with EGFR Mutation (ID 742)
In this phase 3, open-label, randomized study (CONVINCE, NCT01719536), 285 patients (pathologically confirmed NSCLC, positive 19/21 EGFR mutation, treatment naive) will be 1:1 randomized to receive oral icotinib (125 mg, three times daily) or cisplatine (intravenous [IV], 75 mg/m2, day 1) plus pemetrexed (IV, 500 mg/m2, day 1), patients achieving disease control after 4-cycle chemotherapy continue to receive single pemetrexed (IV, 500 mg/m2, day 1) as maintenance therapy until progression. Randomization will be stratified by performance status (0-1/2), smoking status (smoker/non-smoker), disease stage (IIIB/IV), and mutation type (19/21). A total of 228 events would provide 90% power to detect an HR for PFS of 1 at 2-sided significance level of 0.05. Response will be reviewed by both investigator and independent data monitoring committee using Response Evaluation Criteria In Solid Tumors (RECIST version 1.1). Progression Between January, 2013 and August, 2014, 285 patients were randomized and treated at 18 centers from 13 cities in China. The data cut-off was planned at October, 2015 when 228 PFS events were observed in full analysis set (80% maturity). Final results were expected on December, 2015.
ORAL 32 - EGFR WT and MT Targeting (ID 144)
Moderators:K.J. O'Byrne, D.R. Gandara
ORAL32.06 - Intercalating and Maintenance Use of Gefitinib plus Chemotherapy versus Chemotherapy Alone in Selected Advanced NSCLC: A Phase III Study (ID 2108)
This study investigated whether intercalating and maintenance use of gefitinib with chemotherapy improves clinical outcomes versus chemotherapy alone in selected, chemotherapy-naive patients with advanced non-small cell lung cancer (NSCLC) after receiving two cycles of gemcitabine plus carboplatin with stable disease.
We undertook an open-label, randomized, phase III trial at 14 centres in China. Non-smoking patients with previously untreated stage IIIB/IV lung adenocarcinoma with EGFR mutation status unknown (tissue not available) firstly received two cycles of gemcitabine (1,250 mg/m2 days 1 and 8) plus carboplatin (AUC=5, day 1). The patients with stable disease and Eastern Cooperative Oncology Group performance status of 0 or 1 were randomly assigned (1:1) to receive either gefitinib (250mg/d) on days 15 to 25 with a 4-week cycle of gemcitabine and carboplatin or a 4-week cycle of gemcitabine and carboplatin alone. A maximum of four cycles of chemotherapy was allowed in both arms after which time patients continued to receive gefitinib or observation until disease progression or unacceptable toxicity. The primary endpoint was progression-free survival (PFS). Secondary endpoints included overall survival (OS) and safety. The trial is registered at ClinicalTrials.gov, number NCT01404260, and has completed enrolment; patients are still in follow-up.
From June 2011 to August 2014, 219 patients with stable disease were randomized to intercalating and maintenance use of gefitinib with chemotherapy (n=109) or chemotherapy alone (n=110). The number of PFS events is 84 cases for the gefitinib plus chemotherapy group and 93 cases for the chemotherapy alone group. PFS was significantly longer in the patients receiving gefitinib and chemotherapy than in those receiving chemotherapy alone (median 10.0 vs 4.4 months, respectively; hazard ratio 0.475, 95% CI 0.349-0.646; p<0.0001). The median follow-up duration for OS is 24.5 months; OS of maturity 34.7% was not statistically different between these two arms (32.2 vs 32.5 months, respectively; hazard ratio 1.01, 95% CI 0.64-1.58; p=0.97). The addition of gefitinib to chemotherapy was well tolerated, with no increase in haematologic toxicity and no treatment-related interstitial lung disease.
Intercalating and maintenance use of gefitinib with gemcitabine/carboplatin led to a significant improvement in PFS versus gemcitabine/carboplatin alone for Chinese nonsmoking patients with advanced pulmonary adenocarcinoma (EGFR mutation status unknown) who had previously achieved stable disease after receiving two cycles of gemcitabine/carboplatin; immature OS was not statistically different.
P1.04 - Poster Session/ Biology, Pathology, and Molecular Testing (ID 233)
Track: Biology, Pathology, and Molecular Testing
Coordinates: 9/07/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)
P1.04-087 - The Role and Mechanism of Twist1 in Non-Small Cell Lung Cancer Pathogenesis (ID 1215)
Metastasis is a multistep process and the main cause of disease failure and mortality in lung cancer patients. Twist1 is a highly conserved developmental gene involved in embryogenesis that could be reactivated in cancers promoting both malignant conversion and cancer progression through epithelial-mesenchymal transition (EMT). The aim of this study was to investigate the role and mechanism of Twist1 in the pathogenesis of lung cancer.
We examined a series of surgical lung cancer samples from Chinese patients (n=75) and showed that Twist1 expression was linked to lymph node status (P<0.05). To validate that Twist1 is a driver of EMT in non-small cell lung cancer (NSCLC), we used two human lung cancer cell lines (H1650 and H1975, EGFR mutation) and demonstrated that Twist1 was associated with cell growth and mobility.
Overexpression of Twist1 increased cell growth, mobility, and a decrease of Twist1 by shRNA technology reversed the phenomenon. Twist1 promoted the tumor growth in vivo and induced the expression changes of many genes by tumor gene RNA array. Twist1 significantly down-regulated p4EBP1 expression in H1650 cells and up-regulated p4EBP1 in H1975 cells by qRT-PCR and western blot assay.
Collectively, both our in vivo and in vitro findings support that Twist1 in promoting lung cancer by upregulation p4EBP1, which are needed to further study the role of Twist1in NSCLC
P2.04-031 - EGFR Mutation Associated with Histologic Subtype According to the IASLC/ATS/ERS Adenocarcinoma Classification: A Meta-Analysis (ID 1137)
In 2011, the International Association for the Study of Lung Cancer, American Thoracic Society and European Respiratory Society (IASLC/ATS/ERS) proposed the new lung adenocarcinoma histologic classification. The purpose of this meta-analysis is to determine the relationship between EGFR mutation states and different predominant histologic subtypes.
We carried out a comprehensive search for published articles from 2011 to February, 2015, using the PubMed, EMBASE databases and Cochrane Library. The main key words used for search were : IASLC/ATS/ERS, new lung adenocarcinoma classification, EGFR. By searching the databases and further checking the reference lists of the publications, we obtained the initial articles. Next, we performed the preliminary screening through reading the titles and abstracts and excluded the obviously irrelevant articles. Then, we downloaded the full texts and read these articles intensively, excluding articles not giving the detailed data for meta-analysis. We extracted information from all eligible studies as follows: author, publish year, region, total cases, mean age, number of a certain histologic subtype, number of EGFR mutation in certain histologic subtype, total number of other histologic subtypes, total number of EGFR mutation in other histologic subtypes. This meta-analysis was completed using the Stata software (version 11.0; StataCorp LP, College Station, TX, USA). Detailed numbers in each included study were pooled to evaluate the association between EGFR mutation and histologic subtype. A random-effect model was used to calculate the pooled relative risks (RRs), 95% confidence interval (95%CI), and P values. Two-sided P values less than 0.05(P<0.05) were considered statistically significant.
The micropapillary predominant subtype was found to be tended with EGFR mutation (RR=1.37, 95%CI=1.08-1.74, p=0.011). On the contrary, the solid predominant subtype has a low EGFR mutation frequency (RR=0.74, 95%CI=0.59-0.93, p=0.009). Obvious correlation with EGFR mutation states is not found among other histologic subtypes.
Taken together, the new IASLC/ATS/ERS lung adenocarcinoma classification is a very useful predictor of EGFR mutation frequency, the micropapillary predominant subtype has higher EGFR mutation frequency, on the contrary, the solid predominant subtype with lower frequency.
P2.06 - Poster Session/ Screening and Early Detection (ID 219)
P2.06-006 - Diagnostic Accuracy of CT-Guided Transthoracic Needle Biopsy for Solitary Pulmonary Nodules (ID 1478)
To evaluate the diagnostic accuracy of computed tomography (CT)-guided percutaneous lung biopsy for solitary pulmonary nodules.
Three hundred and eleven patients (211 males and 100 females), with a mean age of 59.6 years (range, 19–87 years), who were diagnosed with solitary pulmonary nodules and underwent CT-guided percutaneous transthoracic needle biopsy between January 2008 and January 2014 were reviewed.
All patients were confirmed by surgery or the clinical course. The overall diagnostic accuracy and incidence of complications were calculated, and the factors influencing these were statistically evaluated and compared. Specimens were successfully obtained from all 311 patients. A total of 217 and 94 cases were found to be malignant and benign lesions, respectively, by biopsy. Two hundred and twenty-five (72.3%) carcinomas, 78 (25.1%) benign lesions, and 8 (2.6%) inconclusive lesions were confirmed by surgery and the clinical course. The diagnostic accuracy, sensitivity, and specificity of CT-guided percutaneous transthoracic needle biopsy were 92.9%, 95.3%, and 95.7%, respectively. The incidences of pneumothorax and self-limiting bleeding were 17.7% and 11.6%, respectively.
Taking account of all evidence, CT-guided percutaneous lung biopsy for solitary pulmonary nodules is an irreplaceable, efficient, and safe diagnostic method associated with few complications.
P3.01 - Poster Session/ Treatment of Advanced Diseases – NSCLC (ID 208)
P3.01-050 - A Interim Analysis of Randomized Phase III Trial of Nedaplatin or Cisplatin Combined with Docetaxel as First-Line Treatment for Advanced ASQC (ID 1225)
Cisplatin combined with docetaxel is one of the stand treatment in advanced squamous cell carcinoma(ASQC) of the lung. Nedaplatin combined with docetaxel has demonstrated potent activity in ASQC in phase II study. But until now there is no randomized phase III study comparing these 2 chemotherapy regimens. The aim of this study was to evaluate and compare the efficacy and safety between the combination chemotherapy of nedaplatin or cisplatin plus docetaxel in patients with ASQC.
This is a multicentre, open-label, randomized, phase III study in China (NCT02088515). Chemo-naive stage IIIB/IV squamous NSCLC with Eastern Cooperative Oncology Group performance status 0/1 were randomized (1:1) to four cycles of nedaplatin (80 mg/m[2]) plus docetaxel(75 mg/m[2]) or cisplatin(75 mg/m[2]) plus docetaxel (75 mg/m[2]) . The primary endpoint was progression-free survival (PFS). Secondary end points were overall survival (OS), overall response rate (ORR), disease control rate (DCR) and quality of life.
From December 2013 to January 2015, 117 patients were accrued: nedaplatin plus docetaxel (n = 57) and cisplatin plus docetaxel (n = 60). The objective response rates were 27% and 31% and the disease control rate were 78.92 % and 82.67% in nedaplatin and cisplatin groups, respectively. There is no significance difference in nausea / vomiting(21% vs 30%) , diarrhea(3% vs 5%), liver dysfunction(12% vs 15%), neutropenia(60% vs 65%), thrombocytopenia(10% vs 12%), anemia(8% vs 7%) between the 2 arms. The renal dysfunction incidence is higher in the cisplatin group(3% vs 0%). Although there is no 3/4 grade toxicities difference between 2 arms including nausea / vomiting(0% vs 0%) , diarrhea(0% vs 1%), liver dysfunction(0% vs 0%), renal dysfunction(0% vs 0%) , neutropenia(4% vs 3%), thrombocytopenia(0% vs 0%), anemia(0% vs 0%) . This is an interim analysis and we haven't got the data of survival and quality of life.
There is no ORR difference between the group of nedaplatin plus docetaxel and cisplatin plus docetaxel. But the toxicity of nedaplatin regiment is less toxicities, especially in renal toxicity,as first-line treatment for patients with advanced squamous NSCLC
P3.01-051 - Biomarker Analyses from a Phase II Trial of Nab-Paclitaxel/Carboplatin vs Emcitabine/Carboplatin in Advanced Squamous Cell Lung Cancer (ID 2846)
The administration of nab-paclitaxel/carboplatin (nab-PC) as first-line therapy in patients with advanced non-small-cell lung cancer (NSCLC) was efficacious and resulted in a significantly improved objective overall response rate (ORR) versus solvent-based PC in a phase Ⅲ trial. However, our phase Ⅱ trial (NCT01236716; CTONG1002), which compared the efficacy and safety of first-line nab-PC with gemcitabine/carboplatin (GC) in advanced squamous cell carcinoma of the lung, only showed a marginally improved ORR caused by first-line nab-PC. Meanwhile, the matricellular glycoprotein SPARC (secreted protein acidic and rich in cysteine) and caveolin-1 are potential biomarkers for advanced NSCLC patients receiving nab-PC. Therefore, we retrospectively aimed to explore their predictive and prognostic value using immunohistochemistry (IHC).
From November 2010 to June 2013, 127 untreated patients with locally advanced and metastatic squamous cell carcinoma of the lung were randomly assigned 1:1 to receive first-line nab-PC (nab-P, 135 mg/m[2], d1, d8, q3w; C, AUC = 5, d1, q3w ) or GC (G, 1,250 mg/m[2], d1, d8, q3w; C, AUC = 5, d1, q3w). There were 110 patients evaluable for ORR (nab-PC, 54; GC, 56), 119 evaluable for survival (nab-PC, 57; GC, 62) respectively. However, there were 72 patients with sufficient tissue for IHC of both SPARC and caveolin-1 proteins. Different cut-off values of IHC scoring systems were used to explore predictive and prognostic role of both biomarkers.
The last follow-up was on January 16, 2015. Considering treatment, when the maximum rank method was used for cut-off values, median progression-free survival (PFS) was 7.5 (95%CI: 2.4~12.6) months in higher SPARC-expression arm and 4.3 (95%CI: 2.2~6.3) months in lower SPARC-expression arm for patients treated with GC, HR=0.43 (95%CI: 0.19~0.94), p = 0.030; Median overall survival (OS) was 20.0 (95%CI: 14.7~25.3) months in lower SPARC-expression arm and 10.1 (95%CI: 6.2~14.0) months in higher SPARC-expression arm for patients treated with nab-PC, HR=2.41 (95%CI: 1.08~5.40), p = 0.027. When average method was used for cut-off values, median OS was 18.2 (95%CI: 9.6~26.8) months in lower SPARC-expression arm and 8.4 (95%CI: 5.1~11.7) months in higher SPARC-expression arm for patients treated with nab-PC, HR=2.46 (95%CI: 1.07~5.65), p = 0.029. Regardless of treatment, when the maximum rank method was used for cut-off values, median OS was 14.5 (95%CI: 6.8~22.1) months in lower SPARC-expression arm and 8.4 (95%CI: 5.3~11.5) months in higher SPARC-expression arm, HR=0.47 (95%CI: 0.27~0.83), p = 0.007. When average method was used for cut-off values, median OS was 14.4 (95%CI: 9.2~19.5) months in lower SPARC-expression arm and 8.4 (95%CI: 5.4~11.4) months in higher SPARC-expression arm, HR=0.48 (95%CI: 0.27~0.87), p = 0.013. ORR was not correlated with expression of SPARC, p>0.05. However, there were no significant differences in ORR, PFS and OS between higher and lower caveolin-1 expression arms, p>0.05.
SPARC expression could be a negative prognostic factor for OS of patients with advanced squamous cell carcinoma of the lung, but was not a predictive factor for ORR and PFS, except for patients treated with GC. However, caveolin-1 expression had neither predictive nor prognostic value.
P3.01-076 - Efficacy and Safety of Recombinant Human Tumor Necrosis Factor Application for the Treatment of Malignant Pleural Effusion Caused by Lung Cancer (ID 1148)
Malignant pleural effusion (MPE) is mainly caused by metastatic pleural cancer and defines malignant tumors with a poor prognosis. To achieve sufficient control of MPE and to minimize invasive interventions are the primary goals of the treating physicians. Recombinant human mutant tumor necrosis factor-alpha (rhu-TNF) has been used in the treatment of MPE. The aim of our research study, which included a total of 102 patients with MPE caused by lung cancer, was retrospectively to evaluate efficacy and safety of rhu-TNF application via ultrasound-guided chest tube for the treatment of MPE. Malignant pleural effusion (MPE) is mainly caused by metastatic pleural cancer and defines malignant tumors with a poor prognosis. To achieve sufficient control of MPE and to minimize invasive interventions are the primary goals of the treating physicians. Recombinant human mutant tumor necrosis factor-alpha (rhu-TNF) has been used in the treatment of MPE. The aim of our research study, which included a total of 102 patients with MPE caused by lung cancer, was retrospectively to evaluate efficacy and safety of rhu-TNF application via ultrasound-guided chest tube for the treatment of MPE.
Rhu-TNF was administered as a single dose to 102 patients, and dexamethasone (Dmx, 5 mg) was administered 30 min before rhu-TNF in 35 patients in order to prevent side effects. The primary endpoint was the efficacy of the Rhu-TNF treatment (disease response rate) and side effects (pain, fever and flu-like symptoms) evaluated four weeks after instillation.
The disease response rate of Rhu-TNF treatment in 102 patients was 81.37%. Side effects included 13 (12.75%) patients complaining about flu-like symptoms, 15 (14.71%) with fever/chill, and 14 (13.73%) with chest pain. A significantly higher efficacy was observed for the treatment with three versus two million units rhu-TNF (= 0.036), while the adverse effects were similar. Although application of Dmx before the intra-pleural instillation of rhu-TNF reduced the incidence of adverse events, no significant differences were found.
In conclusion, our study shows that intra-pleural instillation of rhu-TNF in MPE patients achieves sufficient control of MPE and minimizes invasive interventions.
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PTX, Vol. 1 (2012)
by Pentatonix
The 2012 debut EP from the five-member vocal ensemble Pentatonix, PTX, Vol. 1 features a cappella versions of contemporary pop hits. Included are the band's takes on Nicki Minaj's "Starships," Jazmine Sullivan's "Love You Long Time," Gotye's "Somebody That I Used to Know," and others. Also featured here are the two original songs, "The Baddest Girl" and "Show You How to Love." PTX, Vol. 1 is a great introduction to the Arlington, Texas-based group, which previously won season three of NBC's The Sing-Off vocal competition in 2011., Rovi Read Less
The 2012 debut EP from the five-member vocal ensemble Pentatonix, PTX, Vol. 1 features a cappella versions of contemporary pop hits. Included are the band's takes on Nicki Minaj's "Starships," Jazmine Sullivan's "Love You Long Time," Gotye's "Somebody That I Used to Know," and others. Also featured here are the two original songs, "The Baddest Girl" and "Show You How to Love." PTX, Vol. 1 is a great introduction to the Arlington, Texas-based group, which previously won season three of NBC's The Sing-Off vocal competition ... Read More
The Baddest Girl
Show You How to Love
Love You Long Time
Show Fewer Tracks
Vocal > Acappella
CD, Good
2013, Madison Gate Records
Friends of the Phoenix Library
Release: Import
Label: Madison Gate Records
Good. 100% of this purchase will support literacy programs through a nonprofit organization!
2014, RCA
Valleys Books & More
Roanoke, VA, USA
Shipped to you from Goodwill of the Valleys, Roanoke VA. Thank you for your support! The CD, case, and artwork are in good condition showing normal wear.
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Bonfa/De Backer; Bram/Pentatonix; Falk/Hector/Khayat/; Heap; Pentatonix; Remi/Sullivan. Very Good. In very good packaging. Pentatonix-Vol. 1-PTX by Pentatonix.
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Superman - Action Comics (2016-): The Rebirth - Deluxe Edition: Book 1
A lavish hardcover collects the first two volume of legendary SUPERMAN writer Dan Jurgens and superstar artists Patch Zircher & Tyler Kirkham’s bold reimagining of the greatest superhero of all time!
After an extinction-level event that shattered the cosmos, Superman found himself in a world very much like his own, but populated by a new breed of younger, angrier heroes-including a whole new Superman. And when that Superman fell in the line of duty, the original Man of Steel stepped up to take his place.
No sooner does the legendary hero take to the skies than his greatest enemies emerge to face him, from Metropolis’ self-styled protector Lex Luthor to the engine of death and destruction known as Doomsday. Meanwhile, a person-or being-claiming to be the real Clark Kent is dogging his every move. And back in the fields of Smallville, his wife, Lois, and son, Jonathan, face this strange new world as well.
A new era has dawned. Is the Man of Tomorrow ready to face it?
Find out in SUPERMAN: ACTION COMICS: THE REBIRTH DELUXE EDITION BOOK 1! Collects ACTION COMICS #957-966 and JUSTICE LEAGUE #52.
Patrick Gleason Peter J. Tomasi
Patrick Gleason Jorge Jimenez Doug Mahnke
Action Comics (2016-)
Superman returns to Metropolis just in time to meet the city of tomorrow's newest protector: Lex Luthor. But it's not long before these dueling titans meet someone unexpected—the new Clark Kent! DON'T MISS: ACTION COMICS returns to its original numbering!
Superman (2018-)
A bold new chapter for the greatest superhero of all time begins here as the superstar team of writer Brian Michael Bendis and artist Ivan Reis begin their run on the all-new SUPERMAN! The fallout from the Man of Steel miniseries has Clark Kent looking at the world through new eyes...with new ideas about what Superman could and should do for the city of Metropolis and the planet Earth.
Event Leviathan (2019-)
The groundbreaking and always-inventive team of writer Brian Michael Bendis and artist Alex Maleev (Jinxworld’s SCARLET, Marvel’s Daredevil) reunite on a mystery thriller that stretches across the DC Universe and touches every character from Batman to Superman to the Question to Talia al Ghul.
Justice League (2018-)
Spinning out of the cataclysmic events of Dark Knights: Metal and the universe-defining No Justice, the core members of the Justice League--Superman, Batman, Wonder Woman, Aquaman, The Flash and more--are finally reunited! The cosmos suddenly opens up to new threats that the Justice League could not imagine! As Lex Luthor and Batman race to solve a mystery going back to the beginning of the DC
An unknown predator begins outdoing Batman, taking down dangerous threats with military precision. It's up to the Dark Knight and series costar Batwoman to rally and train the young heroes of Gotham City to end this mysterious threat! WHAT NOW: Batman and Batwoman begin training Spoiler, Red Robin and Cassandra Cain, but is the villainous Clayface ready for redemption?
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Apply to LGS!
LGS Committees
All LGS Grads
LGS Graduates by Class Year
PLI Grads
Employer Participants
CNY Political Leadership Institute
LGS Seeks Applicants for it’s 30th Class
(East Syracuse, N.Y. – July 22) – Leadership Greater Syracuse (LGS) is looking for people who believe in Central New York and who want to do their part to make it even better.
“Through a one-year program, LGS immerses Central New Yorkers in our community’s issues and achievements, and gives them the contacts, leadership skills and the courage to effect change,” said LGS Executive Director Pam Brunet.
Each class is comprised of approximately 50 diverse professionals who represent various nonprofit and for-profit organizations in Central New York. The program starts with an overnight retreat in January, and is followed by one full class day a month – February through November. Class days include key community decision makers in all sectors including education, government, economic development and human services.
“Participants in LGS acquire life-long skills that propel them into decision making roles in the community and in the workplace,” said Brunet. While community exposure and leadership skills development is core to the program, networking with fellow classmates and graduates proves to be equally valuable. “Through LGS, people have been inspired to run for office, serve on boards and jobs have been created because of relationships built,” said Brunet.
“A recent survey showed that 85 percent of our 1,200 graduates are still living in CNY. Further, they have served 800 volunteer positions,” said Brunet. “This means that LGS prevents brain drain and improves the community through high level activism,” she added.
“If you are looking to connect with a new network of civic minded individuals from across all sectors in CNY, then LGS is for you,” said Brunet.
The application for the LGS Class of 2020 is available at www.leadershipgreatersyracuse.org. The deadline to apply is August 31, 2019. Call 315-422-5471 for more information.
Leadership Greater Syracuse’s mission is to inspire current and future leaders to make a difference in the community where we live and work. It was founded by Centerstate CEO, Onondaga County, the City of Syracuse and Onondaga Community College. It is supported financially by many organizations including United Radio, VIP Structures, Lockheed Martin, SRC and Community Bank. Media sponsors include Spectrum and The CNY Business Journal News Network.
For more information about Leadership Greater Syracuse, visit http://www.leadershipgreatersyracuse.org.
Leadership Greater Syracuse
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© 2020 Leadership Greater Syracuse | Privacy Policy | Terms of Use
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PM Boris Johnson has ramped up pressure for a general election.
Boris’ huge December election gamble
by Victoria Craw
UK Prime Minister Boris Johnson could get his Christmas wish of a December election after the Labour Party agreed the threat of a no-deal Brexit had been removed for long enough to support the vote.
Labour leader Jeremy Corbyn said the party would support an early election now that his condition of taking a no deal Brexit off the table had been met.
"I have consistently said that we are ready for an election and our support is subject to a 'no deal' Brexit being off the table," he said.
He said the decision from EU leaders to grant a "flextension" until January 31 2020 meant their terms were met for the next three months.
"We will now launch the most ambitious and radical campaign for real change our country has ever seen," he said in a statement.
Shadow Justice Secretary Richard Burgon said: "We'll be supporting a general election, because we want to get Boris Johnson out by Christmas."
The vote could be the first December election in nearly a century and is aimed at breaking the Brexit deadlock in a high stakes gamble for Mr Johnson.
Britain's main opposition Labour Party leader Jeremy Corbyn has been reluctant to hold an election but his party is divided on the issue. Picture: House of Commons via AP.
Boris Johnson has pushed for a general election three times in parliament. Picture: Jessica Taylor/House of Commons via AP
The blonde-haired Brexiteer has repeatedly called for a general election and wants to hold one on December 12, however this was voted down by MPs on Monday in what was his third defeat on the issue.
Mr Johnson's calls are a gamble designed to change the numbers in parliament in order to give the Conservatives an outright majority. They currently govern in a confidence and supply arrangement with the Northern Irish DUP, which has proved a major sticking point with Brexit negotiations.
The uneasy alliance was formed with former Prime Minister Theresa May back in 2017 after she also called a snap election to capitalise on her brief honeymoon period as leader of the Conservatives.
However that decision swiftly backfired when the party lost their majority, leading to the awkward parliamentary arithmetic that has been blamed for the current Brexit impasse.
Since Mr Johnson became leader in 2019 the party's poll numbers have received a boost, but he remains untested by the electorate as leader, and will compete with an energised Liberal Democrat party campaigning for a second referendum, as well as Nigel Farage's newly formed Brexit Party.
On Tuesday, MPs will vote on a plan put forward by the Scottish National Party and Liberal Democrats, who want to hold an early election on December 9.
While the two proposed dates seem close together, the earlier one would reduce the window in which Mr Johnson would have to push through his Brexit bill ahead of parliament being suspended before the election.
The earlier date is also less likely to interfere with university holidays, which some fear could lead to reduced turnout among student voters.
General elections have been held twice in the last four years - in 2015 and 2017. The next is not scheduled to happen until 2022.
Dominic Cummings, right, is Boris Johnson's political advisor and said to be the brains behind his hardline Brexit strategy. Picture: AP Photo/Alberto Pezzali.
Earlier this week, EU leaders granted Britain a "flextension" until 31 January 2020, however Britain is able to leave the bloc earlier if the withdrawal agreement is ratified.
Labour's trade spokesman Barry Gardiner told BBC radio "the first thing" for Johnson to do to get his party's backing was "to ensure that students are not going to be disenfranchised by an election on December 12".
Corbyn did not specify a date in his statement.
"It will be a December election," a Labour source told AFP.
- with wires
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Sport A GRIPPING final day is shaping up across Toowoomba A-grade fixtures today.
News A Toowoomba woman, who runs a placenta encapsulation business in town, is now creating keepsakes using ultrasound and DNA jewellery.
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The Early Learning Centre Way
Baby Day Care (0-12 Months)
Our friendly educators are recognised as a positive and warm-hearted group who love working with children. Our outlook is one of respect for children, their families and their cultural backgrounds.
Meet our Centre Manager
Tayla Anderson
Years in childcare: 4 years
Qualifications: Diploma of children’s services
What makes you passionate about working in childcare? I am passionate about supporting children into becoming capable learners and helping them grow and achieve the skills to further their future. I’m very passionate about building relationships with families so that they feel welcome upon entering the service and a corresponding relationship where we work together towards achieving goals to work on for the best outcome for our precious children that attend our service.
What is the funniest or most memorable moment you can share from working in childcare? My most memorable moment would have to be those moments when you have been working together with a child to achieve a goal they have been trying to accomplish for a couple hours, days, weeks or months and hey finally achieve that goal. The smile that goes across the child’s face with a sparkle in their eyes and that proud moment that you feels. They’re the moments I always remember and love to share with their parent/guardian the moment they’re there to collect their child.
Why do you believe your centre is an excellent choice for parents seeking the best childcare? Here at our centre we like to ensure that the children have the best possible experience and it feels like a home away from home for them. We love to go above and beyond to inspire and nurture individuals to reach their full potential. Ensuring that we are connected to you as families in reaching the desired goals for your child through open and honest communication. The supportive and respectful relationship’s that we build are maintained by making sure our children are our number one priority.
©2020 Early Learning Centre Maddingley | Part of Affinity Education Group Ltd | Privacy | Terms
©2020 Early Learning Centre Maddingley
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The Mad Hatters Bookshop
Mad Rewards
Maybe (#6 Felix & Zelda)
Books > Children > Junior Fiction
$19.99(AUD) inc GST
1946. Europe is in ruins. Millions of people dream of finding happiness somewhere else.Fourteen-year-old Felix is one of them. When he's offered a journey to somewhere far away, he seizes the opportunity. So does someone very dear to him, even though she wasn't actually invited.They have high hopes for their new land, and their dramatic arrival there makes them want to stay. But before Felix and Anya can embrace the love and friendship of their new world, they must confront the murderous urge for revenge still alive in the old. Felix knows he hasn't faced anything like this before. He may not survive, but he's hoping he will. Maybe.
Morris Gleitzman grew up in England and came to Australia when he was sixteen. After university he worked for ten years as a screenwriter. Then he had a wonderful experience. He wrote a novel for young people. Now, after 38 books, he's one of Australia's most popular children's authors.
Imprint : Viking
Produced in : Australia
Author : Morris Gleitzman
The Mad Hatter's Bookshop
Shop 3, 7 Day Markets, 50 Cambridge Parade, Manly 4179 | Phone 07 33935130 | Email : info@madhattersbookshop.com.au | ABN: 18 618 228 318
© The Mad Hatters Bookshop 2020
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Changing Ireland
CrisisJam
Nusight
Voice of the Traveller
We need alternatives, but the Irish left is a joke
Vincent Browne
One of the reasons why we are stuck with the same politics and the same old codgers - in spite of ongoing austerity and deepening inequality - is because the Irish left is a joke. By Vincent Browne.
Four years ago this month, Paul Tansey died suddenly while playing tennis with Shane Ross. Paul had been a brilliant economics commentator first with the Irish Times, then with the Sunday Tribune (where I got to know him in the mid-1980s), and finally again with the Irish Times.
Along with hundreds of others, I queued up in the church in Monkstown in Dublin, waiting to offer my condolences to his widow, Olivia O'Leary, and their daughter, Emily. I found myself beside Brian Lenihan, who had become Minister for Finance a few months earlier, and I talked to him enthusiastically about an ESRI mid-term review that I had read while on holidays.
This mid-term review was authored in the main by the ESRI's chief economist, John FitzGerald, who in 1986 had been the first to see that there was going to be a boom in the Irish economy in the 1990s. The review suggested that, while there was a dip about to occur in the Irish economy, it would be a mere blip, and everything would resume as before in the next six months to a year.
I asked Lenihan why he and the new Taoiseach, Brian Cowen, had failed to convey that sense of optimism. Lenihan said it was because they did not share that sense of optimism and because there were rough times ahead.
I thought it was a pity that Paul was no longer around to lend his expertise. Actually, I think now that Paul would have disagreed with the ESRI projection from the outset - not just because he was a pessimist instinctively but, because of his intelligence and economic expertise, he would have read the signals of a collapse, signals evident almost immediately after the ESRI published its unfortunate prognosis.
But Paul would not have fully anticipated what has transpired in the four years since; nor, of course, did John FitzGerald, nor Brian Lenihan and certainly not I. Four years of economic decline, budgetary nightmares, banking collapses, debt mountains, never-ending austerity, cruel cuts affecting the livelihoods of the least well-off - with a further four (or eight, or 12) years of the same yet to come.
If we'd had the perspicacity to anticipate all this, surely we would have expected that such a calamity would cause political upheaval, involving a rejection of the neoliberal doctrines that propelled us - and so much of the rest of the world - into this catastrophe, with a rejection of the political parties and personalities that had imposed their pernicious models and doctrines on us?
We surely would have expected the emergence of a very different political culture, inspired by a very different brand of politicians, bringing us back (or it is forward?) to the values of solidarity, the values of the collective.
But precisely the opposite has happened. The very same parties that brought us into this mess - Fine Gael and Labour were just as much part of the culture that drove the Celtic tiger as Fianna Fáil and the Progressive Democrats - are in office. The same ideology that brought us into this crisis remains the dominant force, except with sharpened claw and tooth. Worse still, we have forfeited forever large parts of our sovereignty to European institutions which are even more driven by that ideology than we are. And we are about to forfeit even more of what remains of our sovereignty in the context of a more centralised Europe, currently being devised.
If you wonder how this has happened, you may ponder how our media, along with the political establishment, have propagated the culture of neoliberalism, the ideology of individualism, of everyone for himself/herself, of there being "no alternative", of the unavoidable disciplines of markets, of the "irrationality" and impracticality of equality.
But you might also wonder about the Irish left.
Just observe the farce of Clare Daly's resignation from the Socialist Party and the probable consequential collapse of the United Left Alliance. Is it plausible that people serious about the creation of an alternative force in Irish politics, absorbed in elaborating a credible programme to create a different and more equal society, would be diverted by a personally-motivated equivocation over, essentially, an irrelevance - Mick Wallace's false tax declaration?
One suspects that the reason why there is a hullabaloo over this equivocation is because the left here is not about much else. No serious attempt has been made by any of these left-wing TDs to devise a credible alternative programme. Yes, there are soundbites about taxing wealth and debt default, but no concrete costed plans, showing how we get from here to the kind of society that they claim to envisage.
Remember the hash they made of the Fiscal Treaty referendum campaign, and their refusal to address a central question in voters' minds, i.e., where would we get necessary funding if we could not access ESM funds?
One of the reasons why - in spite of this ongoing austerity, this incremental surrender of sovereignty forever, the massively unjust debt burden, this deepening inequality, these cruelties inflicted on those least able to bear them - we are stuck with the same politics and the same old codgers, is because the Irish left is a joke.
Murphy: Broaden tax base to create a decent society
Speaking during RTE's Prime Time budget debate, lecturer in Irish Politics and Society
Budget 2014: Don't Just Read the Label, Look inside the Tin
So, Fine Gael has caved in to Labour.
Stop digging on issue of raised bogs
A lost family photograph of ours evokes a particular memory for me.
Open government initiative seeks public engagement
Openness and accountability are hot topics – but this isn’t a story about Edward Snowden, the NSA
Ethics in banking a question of regulation
Last week former Taoiseach and President of IFSC Ireland, John Bruton, said that the banking indu
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Diane Meyer Simon
Founder, Global Green USA, Montecito, California former wife of Indiana real estate billionaire Herbert Simon
Edited by mooninmyname 4 months ago History
Diane Irene Meyer graduated with a B.A. in Psychology from Butler University, in 1968, on a four-year scholarship. During the spring 1968, her...
Diane Irene Meyer graduated with a B.A. in Psychology from Butler University, in 1968, on a four-year scholarship. During the spring 1968, her senior year, ironically Diane cut an evening Shakespeare class in order to attend a Robert F. Kennedy rally at an inner city park in Indianapolis. The large crowd waited for hours in the unadorned park to finally see and hear Robert F. Kennedy make the chilling announcement that Dr. Martin Luther King had been assassinated.
Some years later, Diane spoke of that dreadful day in 1968, crediting the experience and the words of Bobby Kennedy as the turning point in her life's ambition. The day following Martin Luther King's assassination, Diane took a leave of absence from Butler University. She began working for the 1968 Robert F. Kennedy Presidential Road Show, as a traveling press/media assistant to the late Dick Drayne. This allowed Diane to be on the road daily with Kennedy, along with national and international Press/Media though out the campaign.
In retrospect, following the strength of her convictions and the dynamics of her grounded emotions, this event lead Diane from a life in the small Amish community of Nappanee Indiana, to national and global realms of public service.
Fortunately, the Kennedy staff urged her to work for the most honest, decent, and wise leader, US Senator Birch Bayh. Senator Birch Bayh was running for re-election against the formidable William Ruckelshaus in 1968. Diane continued serving Senator Birch Bayh for twelve years.
Diane operated in almost every aspect of the US Senate staff work, spent some time in graduate school until becoming Indiana Administrator of Birch Bayh's office. During this time, Diane Meyer married N. Stuart Grauel who had become Deputy Secretary of State to her friend Larry Conrad. When Senator Bayh was not running for Senate or President, she would take leave to help Conrad and other Democratic Presidential Candidates, always returning to Senator Birch Bayh's office. Her marriage ended in 1976.
In 1981, Diane Meyer married Herbert Simon, becoming Diane Meyer Simon, political activist, social catalyst, wife and stepmother of two teenagers. Soon, Diane and Herb became the proud parents of three, two daughters and one son; all the while, maintaining her political and social commitments and beginning a business career. Diane has founded several companies involving environmental consulting and design.
Diane has organized countless benefit fundraisers for State and National Democratic candidates. She has anonymously donated food, clothing, education, housing, and adopted families, providing overall safety and care for many single-parent women and their children. Struggles with which Diane identifies, as she and her mother experienced homelessness when she was young. She left an affluent childhood when she was almost five years old, her mother & she left to escape the abuse of her brilliant, but emotionally broken down father. Diane and her mother were forced to live with relatives for five years. Diane was an only child, born to a French father who was a teacher, an Air Force Pilot and medical doctor and a French-Swiss mother who was both a teacher and a nurse.
Diane has devoted her life to numerous organizations and businesses spanning Indiana, where she was Indianapolis Woman of the Year, and California, where she moved in 1989. Diane Irene Meyer Simon is Founder, President Emerita and Past Chair of Global Green USA. Diane founded Global Green USA (GG USA) following a Moscow Board Meeting of Green Cross International (GCI), August 1993, with the Honorable Mikhail Gorbachev, President. There, GCI Founder and President Mikhail Gorbachev personally enlisted her to organize a US affiliate and become a Member of the GCI Honorary Board. Since then, Diane has committed herself to personally spearheading the GG USA agenda and molding a message of international environmental responsibility for an American audience.
As President of Global Green USA, Diane brought to fruition a political career as staffer, organizer, administrator, fundraiser and strategist. Over the years spanning 1993 to the present Diane has remained the driving force in representing an agenda and a vision for Global Green USA and Green Cross International.
Today, Diane Irene Meyer Simon primarily lives in Montecito, California and occasionally in Indianapolis, Indiana, where she maintains her second home. Her marriage ended in 2000.
She shares her homes with her three children, Sarah Elisabeth, Rachel Mariam, and Asher Benjamin Meyer Simon.
• BA, Psychology (?→'68)
N. Stuart Grauel Indiana Deputy Secretary of State
• husband (?→'76)*
Herbert Simon Simon Property Group billionaire, NBA owner
• husband ('81→'00)*
Donation/Grant Recipients
Showing 1-10 of 185 :: see all
DNC-Non-Federal Individual
• 14 contributions · $347,000 (Feb 18 '92→Sep 25 '02)
Democratic Senatorial Campaign Committee Political Fundraising Committee for Democratic Senatorial Candidates
• 33 contributions · $128,825 (Mar 9 '90→Sep 20 '16)
Hillary Victory Fund
• 20 contributions · $109,874 (Feb 8 '16→Oct 4 '16)
DNC Non-Federal Unincorporated Association Account
• 2 contributions · $60,000 (Mar 17 '00→Mar 31 '00)
House Majority PAC
• 29 contributions · $48,575 (Apr 30 '15→Oct 31 '16)
Indiana Democratic Congressional Victory Committee
• 18 contributions · $48,482 (Feb 17 '99→Sep 28 '16)
• 54 contributions · $45,450 (Sep 29 '06→Aug 1 '16) [+1]
• 7 contributions · $11,000 (Oct 5 '99→Oct 25 '02)
Alan Grayson US Representative from Florida
• 58 contributions · $41,570 (Jul 1 '15→Aug 22 '16)
Baron P Hill US Representative from Indiana
• 30 contributions · $34,400 (Oct 4 '89→May 3 '16)
Types Person, Business Person
Number of documents: 839 :: see all
The Patriotic Millionaires (2016)
Diane Lander
Diane G Simon
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Read Our Latest Issues
About Living Magazines Cardiff
Advertising Cardiff – Some Testimonials
Cardiff Business Directory
Community Awards 2019
Free, multi award-winning magazines for North Cardiff
Llandaff City CIW Primary School at 50
By Editors Living Magazines
Llandaff CIW Primary recently celebrated its 50th birthday. Former pupils and members of staff explain what the school means to them
Matthew Lewis, Pupil 1979-1986
I still remember my first day quite vividly: being asked to find my book drawer and coat peg which were marked with a sticker of an orange car; then being gently introduced to the class by Mrs Rudge. For me, it was the start of actual memories and also of a long period of stability, something I’ve been anxious to provide for my own children through the challenges presented by my job.
I’m most fond of the small snapshots of memories; playing on the logs and climbing frames of the infant school; the smell of the polish on the floor of the two assembly halls; ‘Music and Movement’; and the garish pattern on the curtains. I fondly remember all seven of my teachers, but the last three were particularly influential: Mr (David) Watkins, who taught an entire generation to love rugby; Mrs (Mair) Price, who loved poetry and gave many of us our first understanding of Welsh; and Mrs (Valerie) Wilson, who was never flustered and never cross.
Some of my earliest memories include being sat enraptured by Mr Sutton’s stories of being a child in South Wales during the war; discovering and loving Little Donkey (the carol) in Mrs Rudge’s class; drinking unpleasantly warm milk from miniature bottles through a little blue straw; and Miss Samuel – my first headteacher. She was always a little stern but always very fair. I also remember the kindness after I’d once thrown up on the stairs (and that strange sand-like disinfectant that got scattered over the affected area).
Some of my most precious memories include scoring a try in front of my parents in (I think) 1983 during the ‘Dragons vs Druids’ 7-a-side. I was always a fairly mediocre rugby player so this is still etched in my memory as my ‘JPR’ moment.
One of my happiest memories was being dressed in stripy Victorian-style bathing costumes (made from bed sheets), complete with boaters and painted-on moustaches for our Victorian Music Hall end of year concert. It was our last day at the school and myself and Matthew C took to the stage hamming up Oh I Do Like to be Beside the Seaside. It felt funny, sad, but mainly very happy. We left the school with such optimism that summer.
There was definitely an ‘old fashioned’ feel to the school and the teaching staff, without necessarily being ‘fusty’ or outdated. Now in my 40s, my handwriting is still exactly the same style as I was taught by Mrs Lark in about 1982 and I’m often asked by my own children why it is so old-fashioned and ornate. I also remember there always being music; always a teacher who could play the piano and a broad repertoire of hymns; the words to Autumn Days still make me smile.
I moved on to The Bishop of Llandaff High School in 1986 and then to Aberystwyth in 1993 where I read Political Philosophy. I went to Sandhurst a couple of years after graduation and have been in the Army ever since.
Heather Fry, Teaching Assistant 1979-2008
I started working as a teaching assistant at the school in 1979 and I was there for 32 years.
It was almost like a private school with lots of lovely families. I started off part-time and Margaret Samuel was the Headteacher then. She was animal mad. We had a budgie called Bobby and he sadly died. Margaret decided to bury the budgie in the school grounds, involving the children to show them the theme of life and death. They buried the budgie and one of the children went home and told his parents that Mrs Samuel had planted Bobby! We also had a rabbit that kept eating the curtains and a cat that used to visit every day.
We were all happy there and there were lots of memories.
We went to Cefn Onn one day and one of the children, George, fell in the pond. On one occasion we went to Bristol Zoo and the bus caught on fire on the way home on the M4!
We all worked until we dropped. I remember seeing Margaret [Samuel] lying flat out on her office floor because she was suffering from a migraine. But we knew how to enjoy ourselves too. We had lots of dances where we all dressed up and at one dance, Margaret dressed up as Margaret Thatcher, even though she couldn’t stand her.
We buried a time capsule on one of the banks 25 years ago and that’s still buried there as far as I’m aware. We also used to take the children around the village at Harvest Festival giving out gifts. The Church had a huge influence on the school. The Dean used to come to the school, mostly on Fridays. He helped plant a tree in 1973.
In 1991, we went to the cathedral to see Princess Diana and Prince Charles when they visited. We’d been waiting and the children had been clutching these daffodils all morning. By the time Diana and Charles finally got around to us, the daffodils were drooping but Diana accepted them as if they were a £100 bouquet. She was wonderful with the children, she really was. They brought William too. He was 6 years old at the time.
After 28 years at the school, I had to have hip surgery but still helped out in the office for another four years.
Rachel Mainwaring, Pupil 1979-1986
My reception teacher was a lady called Mrs Rudge. Miss Samuel was the Headteacher of the Lower School. I still clearly remember sitting down for a glass of milk every day and being able to dress up with the fancy dress clothes.
I once wore a pair of rubber lips in to school and was messing around with them, blowing kisses to the boys and Miss Samuel confiscated them. I was mortified as I considered myself to be a good girl up until that point!
I remember the school concerts really well too. In my first year, I was the tinsel fairy and my mum made the most brilliant costume. I had to dance around the Christmas tree and add tinsel to it. I felt very pretty and important.
One of my favourite teachers was Mrs O’Shea. She once wrote in a school report that I had a very sunny disposition and was very chatty, perhaps a little too much and that has never really changed!
Another teacher who made a real impact on me was Mr Jenkins. Not only was he very handsome (he look very similar to Magnum PI), he was also a fantastic swimmer and took a group of us to Atlantic College for a lifesaving course. There aren’t many people who can persuade me to get up at a ridiculous time to swim in the very cold sea but he did.
I loved the Eisteddfods, and often played the piano and did the English recitation. I also remember being a flower girl and learning a folk dance which the boys had to join in with too, much to their dismay.
When I left, I went on to Bishop of Llandaff High School and then obtained a degree in journalism from Cardiff University. After 21 years as a journalist, I am now a freelance writer and communications specialist.
Judith Thompson, Pupil 1967-1968
I started in the reception class of the old Victorian school in 1961 aged four.
My classmates and I made the transition to the new school in September 1967 for our last year of junior education. There were still two separate buildings for Infants and Juniors but the Junior building had an ‘upstairs’.
My teacher was Mr Griffiths and the teacher of the other Standard 4 class was Mr Sutton. We all loved our new school building. The classrooms were so big and bright with huge windows. We could see out over the whole school grounds. The old school had been cramped and dingy with high ceilings and raised narrow windows.
Each new classroom had a side room with a big metal sink where we could prepare and clean up our art equipment. We also had a big new hall that could accommodate all the junior pupils together for our assemblies, concerts and plays. We even had a new piano!
Outside, we had a much bigger playground and a large field to play on and to use for our PE lessons. In the old school, all we had was a very small concrete yard. And all the new toilets were indoors without spiders!
The following September, 1968, I moved on to the Bishop of Llandaff High School, then in 1975 to Aberystwyth University to study for a BA Joint Honours in History and Classical Studies. I then took a fourth year at Aberystwyth to take my PGCE and train as a primary teacher.
My first teaching practice was at Llandaff City in 1978 in a Standard 1 class with Mrs Lark, who had been my teacher in the old school. I went on to teach for 37 years – my last 16 years teaching pupils with severe and complex learning needs.
Jo Kenyon, Pupil 1982-1990
My first teacher was Mrs Rudge and I thought she was great.
Reading was one of my favourite things to do and in the Infants, story time at the end of the day was a highlight.
I remember having a half day’s holiday for St David’s Day and a girl in my Reception class who used to eat crayons regularly. Learning to tell the time in Year 2 with Mrs Selby was one of my most precious memories – I was so proud when I mastered it!
Gymnastics was my worst area – I really had a mental block when it came to doing a forward roll, despite practising for hours on my bed at home. Mr Jenkins, the ‘scariest’ teacher in the Junior School, knew I needed help with it, so every time he passed me in the corridor he’d call out to me and make me try a forward roll there and then!
Everything felt ‘close’ in the school. Everyone knew each other and the school had a really happy ‘buzz’ around it, while the staff still had the authority and respect from all the children. The teachers knew all our strengths and areas needing development, encouraging and supporting us.
I went, as most children did, to Bishop of Llandaff High School and then on to Cheltenham & Gloucester College of Higher Education. I qualified with a Batchelor of Education with Qualified Teacher Status.
In my final term at Cheltenham, I saw a job advertised at Llandaff Primary and applied. Though I didn’t get the job, I went and did a week’s supply work there and never really left. It was a little strange at first, sitting in a staffroom with teachers who had taught me 13 years or so before – but I think they actually found it harder than me. I worked there for the next four years and thoroughly enjoyed my time there.
David Morgan, Pupil 1976-1983
In the Infants, I had Mrs Harper for two years and Mrs Selby for the other. I remember having a classroom in a corner of the school hall. I also remember being Little Boy Blue in a school production. And I remember going down steps on the left to the toilets, with tracing paper for loo roll!
In Standard 1, I had Mrs O’Shea who was amazing and used to read us the Adventures of the Robber Hotzenplotz, which I adored. We were in a classroom at the very back of the school building.
In Standard 2, I had Mrs Lloyd and we grew tadpoles into frogs. In Standard 3, I had the scary Mr Smith. Woe betide you getting ‘Smithlicated’ (basically put in a headlock) if you did something wrong. I remember that we made lots of arty things with him, including Viking longboats using match boxes in the middle.
My final teacher, in Standard 4, was Mr Sutton. He was a wonderfully kind man who taught us loads of stuff about the world, from classical tales and history to music and art. Nowadays he would probably be too restricted by the curriculum and targets.
The other teachers that I remember are Mrs Lark, Mrs Ashworth (whom I seem to remember being sick over on the way back from swimming at Guildford Crescent) and the wonderful Mr Watkins, our beloved rugby teacher who died at a tragically young age. Our Head was Mr Powell, who was a distant figure to me. He had a twin – and that freaked me out after he passed away.
The school was a real family. It was small enough that everyone seemed to know everyone. I loved the location too. On my walk home, I could go to the newsagent in the High Street to get The Beano or Whizzer and Chips.
I loved school; I ended up going to Bishop of Llandaff, which I also loved. I went on to study Biology at Cardiff University, then teacher training and a Masters at Canterbury Christ Church University. I am now in my 25th year of teaching – an Assistant Headteacher near Margate in Kent.
Iris Selby, Teacher 1967-1991
When I first started teaching at Llandaff Primary (the old school), there were two classes in each classroom, 30 children down one end with the teacher and 30 children down the other end with their teacher. On top of that, the Head would be sat with us – that’s how crowded it was! When we moved to the new building, it was desperately needed. Many years before that, the kids would bring a penny to put towards the new school. I’m probably the only person alive who has taught at both the old school and the new school.
My son was in the first class in the new school. I’ve got a photo of him pointing to a board and on the board it says ‘Today I am 7 and today is Tuesday September 5th 1967.’
I was very happy in the new school as I had my own room. Margaret Samuel came as the Head after about two years at the new school. It was lovely because the children were so well-behaved – they’d been brought up well at home. We got told not to teach times tables by the Education Department at one point and when we went to a conference, I let on that we were still teaching them and got told off!
We also had an inspector in from London once who was horrible and told me that I needed to learn – I’d been teaching there 23 years! She went straight to Margaret Samuel to complain about me and when Margaret asked who she was referring to, she replied ‘the blonde piece!’
A while later, she came into school and was met with an autumn wall display that my class had produced and this inspector was so impressed, she even wanted photos of it. She asked Margaret who’d produced it and Margaret replied with the words ‘the blonde piece!’
I used to get the kids to write stories, against advice that I shouldn’t because the ‘kids couldn’t spell’. I created word diaries for the children to write in from sheets of paper that my husband would bring home from work. I’d spend hours stitching them together for the kids to write in.
Rachel Loaring, Pupil 1979-1986
I don’t remember being worried on my first day at Llandaff City as many of my friends from nursery were also joining the school, and my older brother was there already.
Miss Samuel was the Headmistress and I remember always thinking she was quite strict and frightening – all the children were fearful of being sent to her office. My reception class teacher was Mrs Rudge, who I recall being a warm, jolly lady, everything you would want as a Reception teacher.
I do recall one incident in her class when I was painting on the easels in the corner; myself and another girl (Nicola Harries) thought it would be fun to express our artistry by painting on each other – Mrs Rudge did not approve!
Mrs Harper was my next teacher – I was disappointed as I wanted Mrs Selby because she gave out stickers to her class each week for learning their times tables. Memories of this year at school include building robots out of egg boxes and toilet rolls, and newly hatched chicks being brought in by the mum of one of my classmates (Matthew Lewis).
I also remember our Christmas play being themed around a boy and a girl decorating a Christmas tree. We had taken in decorations from home and the teachers had decided what decorations were going to be used. Rachel Morgan (now Mainwaring) and Lisa Finlayson were the tinsel fairies (chosen because they were the smallest girls in class, both with long blonde hair), Matthew Green was a cracker and Hayley Wainwright and I were Japanese ‘geisha’ girls because I had taken in my Nana’s old decoration of a silk parasol made from a handkerchief – it obviously had nothing to do with Christmas other than being something my family had always put on our tree.
I recall playing in the playground at break times. I loved climbing on the logs they used to have at the bottom of the playground near the scout hut (where I had gone to nursery). I also remember playing on the climbing frames, and falling off them and banging my head and scraping knees many times onto the tarmacked playground (no Health and Safety in those days).
I went to Bishop of Llandaff High and then gained a 2.1 in Geography from Bristol University. After working as a chartered accountant for over 15 years, I made a life change and moved into the education sector and am now a bursar at an all-girls independent boarding and day school.
Helen Biggin, Governor 2000-2009
My very first involvement with Llandaff City Church in Wales Primary School was when Gregory, the eldest of our four children, joined Mrs Clarke’s Reception Class in September 1992. He still has close friends from that time – as indeed do I from among the parents.
After being involved with fundraising at the beginning of the ambitious new build project, I became a Foundation Governor in 2000 and was elected Chair of Governors a year later, a post I held until 2009.
On a personal level, my loveliest memories of the school are seeing all four of our children thrive there, and the sense of belonging and community it engendered in them. The sports days, nativity plays, Easter parades, concerts, productions and school fairs were such enjoyable, inclusive affairs, if chaotic at times.
With my governor hat on, I was pleased with the work we did to complete a major building project which created an excellent environment for the pupils, staff, parents and the wider community. It was great to foster productive relationships with Llandaff Cathedral, other nearby churches and organisations and local people, which benefited the children by putting them at the heart of community activity.
What made the school special was its strong Christian ethos and the values it promoted of love, respect, tolerance and kindness. While good academic standards – or success in sport or drama or singing – are, of course, always important, the school also succeeded in helping children realise their individual potential.
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Ugly Girl Killed
CASPER, WY—The people of America remained unmoved Monday as the sparse, barely attended funeral procession of Edith Pelphrey made its way to Pinelawn Cemetery in downtown Casper.
The recent murder of clumsy, unattractive, 6-year-old Edith Pelphrey, pictured above in happier times, has not sent shockwaves of grief and despair rippling through the nation.
Edith, a homely six-year-old with thick glasses and a decidedly non-winning smile, was laid to rest largely as she had lived—unnoticed by the general population.
Discovered strangled with a length of nylon cord on Jan. 4, reported to the police Jan. 15, and finally investigated two days ago, the story of unattractive little Edith and her savage killing has failed to tug at America's heartstrings.
To the few who knew her, Edith was an unattractive, awkward little girl who failed to stand out among her first-grade classmates at Jefferson Elementary School. And it is this lack of social grace, more than anything, that makes her all-too-brief life—and its all-too-brief ending—all the more not-compelling and non-poignant in the eyes of a city and a nation.
The normally lively streets of Casper were quiet today. Not because the city was mourning a loss that had shaken it to its core, but because of the capacity crowds attending this weekend's 1997 "Li'l Miss Casper" pre-teen beauty pageant, a contest that Edith, had she lived, surely could never have entered, let alone won.
Edith's death—so sudden, so unremarkable—has not sent shockwaves of grief and despair rippling across the land.
"The American people face bold new challenges in the 21st century," President Clinton said Monday in an unrelated speech which made no mention of the incident. "We will rise to meet these challenges together."
Said Time magazine editor Richard Turner, "I want to stress that we have no intention of featuring Edith Pelphrey on the cover of Time."
"Neither will we," concurred People magazine's Kathie Holcomb. "There's just no sell."
But who was Edith? What was she going through as she neared the end? In these modern times, do we as Americans even care about such questions? The answer is clear, and it is: no, we do not. But now, after what little tears there were have long fallen, lingering questions about Edith's murder remain, failing to elicit anything beyond indifference from anyone.
"I was just going to the bookstore," said Casper resident Dan Vermeer, 24, moments after learning of Edith's death. "After that I'm supposed to meet a friend at a coffee shop."
"Hey, look at this!" a visibly agitated Rev. Geoff Noyes, of Casper's First Methodist Church, said to MaryAnn, his wife of 43 years. "They're having a sale at Safeway! Look at those tuna discounts."
These Casper residents, like millions of people across the nation, will not form any sort of activist group or mobilize to find Edith's killer; launch any sort of posthumous tribute; order any flower arrangement; or sing moving hymns in her memory. Neither, for that matter, will they ever know who she was, nor would they care to.
Why was she found strangled in her own home? There was a ransom note found with the body, but no kidnappers or, for that matter, evidence of any kidnapping at all. Could it be that the murderer was actually someone from the Pelphrey family itself? By and large, nobody could care less.
"I told you already that I have no idea what you're talking about, sir. If you keep calling here I'll have you fined," Casper chief of police Wayne Daugherty told reporters.
It's obvious that Edith, too homely to give a second thought about in life, is even less likely to attract anyone's attention now that she has been laid to eternal rest.
"I feel deeply, with every ounce of my soul, that something must be done to ensure the public that no matter what happens in the future, this night will not be forgotten, and that the Li'l Miss Casper Beauty Pageant will continue to inspire us all," Casper Mayor Roger DiNizio said, addressing an assembled crowd of 11,000.
Upon the completion of DiNizio's remarks, the pageant audience—decked out in their finest for the occasion—cheered, rising from their seats in a spontaneous standing ovation.
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CCP Announces Details For EVE Fanfest 2014
CCP Games, the world’s leading independent developer of massively multiplayer games, today announced the first round of programming for the tenth EVE Fanfest, the massive gathering that will celebrate eleven consecutive years of growth of the EVE Universe.
EVE Fanfest is the annual festival at which over 1,000 EVE Online capsuleers, DUST 514 mercs, soon-to-be EVE: Valkyrie pilots and their friends and family come together in Reykjavik, Iceland, for three days of celebration. This year promises to be the most expansive Fanfest yet as the three different games set in the EVE Universe converge into a single fan experience.
Unique events supplement the amazing panels, presentations, PvP tournaments, exotic local excursions, game demos, round tables, developer pub crawls, concerts, parties and unprecedented access to the development team. Highlights include:
The first live demo of EVE Online‘s summer expansion and more information about the long-term vision for game.
Reveals of what’s next for DUST 514 and a world-first hands-on opportunity with its next major evolution.
Exclusive hands-on with an entirely new build of the virtual reality dogfighting game EVE: Valkyrie and details about what’s in store for the game recently announced as an Oculus Rift launch title.
A special dedication ceremony for the “Worlds Within a World” monument to EVE players. This unique event, taking place in picturesque Reykjavik Harbor where the monument will be installed, will feature the monument’s creator, Reykjavik city officials and players from around the world.
The “Make EVE Real” speaker track returns with visionary scientists outlining how the science fiction portrayed in the EVE Universe might not be that far off from reality. Among the speakers is Dr. Michael Meyer, who will speak about his work as the lead scientist for NASA’s Mars Exploration Program and how the Curiosity rover has changed the way mankind searches for extraterrestrial life.
Headlining the legendary convention finale, the “Party at the Top of the World,” are musical acts Z-Trip (US) and FM Belfast (Iceland). Z-Trip returns triumphantly from last year’s massive DJ set and FM Belfast is back again after their killer 2010 performance.
Further updates on CCP’s transmedia projects, such as the company’s collaboration with Dark Horse and its partnership with director Baltasar Kormákur on an EVE television series.
That’s just some of what EVE fans will be able to look forward to. Much more will be revealed between now and the end of April–including the final schedule–with several surprises in store for the event itself.
Tickets for EVE Fanfest and more information about the event can be found at: http://fanfest.eveonline.com. Fanfest 2013 sold out, so anyone interested in attending should act fast.
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@HalaJaber
The delay for the OPCW’s FFM team to enter #Duma & commence their investigation, is at the request of The United Nations Department of Safety and Security (UNDSS). opcw.org/fileadmin/OPCW…
12:17 PM - 18 Apr 2018
Replying to @HalaJaber
.2/ On 16 April, we received confirmation from the National Authority of the Syrian Arab Republic that, under agreements reached to allow the evacuation of the population in Ghouta, the Syrian military were unable to enter Douma.
.3/ The security for the sites where the FFM plans to deploy was under the control of the Russian Military Police.
.4/ The UNDSS made the necessary arrangements with the Syrian authorities to escort the team to a certain point & then for the escort to be taken over by the Russian Military Police.
.5/ However, the UNDSS preferred to first conduct a reconnaissance visit to the sites, which took place yesterday. FFM team members did not participate in this visit.
.6/ On arrival at Site 1, a large crowd gathered and the advice provided by the UNDSS was that the reconnaissance team should withdraw. At Site 2, the team came under small arms fire and an explosive was detonated. The reconnaissance team returned to Damascus.
.7/ The UNDSS will continue to work with the Syrian National Authority, the local Councils in Douma, and the Russian Military Police to review the security situation. At present, we do not know when the FFM team can be deployed to Doum
.8/ I shall only consider such deployment following approval by the UNDSS, and provided that our team can have unhindered access to the sites.
.9/ For those of you who are not familiar with the works of the UNDSS, in effect the security advising body for the U.N., no delegate or U.N. related organisation can move in volatile areas without being given the clearance & go ahead by the UNDSS.
.10/ It is irrelevant whether journalists, government officials, or aliens for that matter, visit any particular site. If the UNDSS deems it unsafe then any UN org in question cannot travel there. They will only do so when they get clearance from UNDSS itself. Not from any1 else.
.11/ FYI: This is not just the UNDSS’s role in Syria nor is it limited to Duma... the same system applies everywhere the U.N has presence and where security issues are a concern. The same system of checks and balances are used and also applied in Iraq, Yemen, Libya, Syria etc...
Replying to @threadreaderapp
.12/ @threadreaderapp please unroll. Thanks.
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Category: Nintendo
The original Crash game is coming to a Nintendo Console
Last week Nintendo revealed that the Crash Bandicoot N. Sane Trilogy would be coming to the Switch. This is ironic because Crash was once a Playstation icon. The original Crash game has never been on a Nintendo system before. I have been looking forward to playing this game since it came out on the Playstation 4. What do you think of being able to play the original Crash game on a Nintendo system?
Posted on March 12, 2018 March 12, 2018 Categories NintendoTags crash bandicoot N Sane TrilogyLeave a comment on The original Crash game is coming to a Nintendo Console
Nintendo Reveals Super Smash for Switch
Nintendo recently held a direct where they announced that Super Smash would be coming to the Switch in 2018. The trailer that they showed off revealed that the two main inklings from Splatoon would be in the game. It also showed a shadow of Champion Link and possibly Mario from Odyssey. I am excited that a new Super Smash is coming to Switch this year. However I hope it isn’t a glorified Wii U port. The amount of ports on the Nintendo Switch is ridiculously high.
Posted on March 12, 2018 March 12, 2018 Categories NintendoTags super smash switchLeave a comment on Nintendo Reveals Super Smash for Switch
Nintendo announces Labo
This week Nintendo announced a new product called Labo. Labo is an interactive cardboard kit for the Nintendo Switch. There are two kits that will be coming out on April 20th. Toy-Con 1 retails for $69.99 and Toy-Con 2 retails for $79.99. Kit 1 comes with a house, 2 RC cars, a fishing rod, a motorbike and a piano. Everything is controlled with the two Joy-Cons. Kit 2 comes with a robot suit. Each kit comes with software as well.
I think this is a very unique idea, and it will be great for younger kids. I like how interactive it is. I think that the piano, the RC cars, and the robot suit look the most interesting. What do you think about Labo?
Posted on January 21, 2018 Categories NintendoTags Interactive Cardboard, Labo, NintendLeave a comment on Nintendo announces Labo
Surprise Nintendo Direct Mini
Nintendo had a surprise direct for us today. They revealed several games release dates and they also announced several new titles in the works. Mario Tennis Ace was announced in todays direct. It will continue the Mario Tennis series with a story mode. It is due out this spring. Another title that was announced is Hyrule Warriors Definitive Edition. It will include all the DLC from the 3DS and Wii U title. It is due to release this spring as well. Nintendo also announced that Dark Souls Remastered would be coming out on May 25th. Nintendo gave us a release date for the upcoming Kirby game as well. It will come out on March 16th.
Nintendo really out did themselves with this mini direct. They also revealed DLC for several games. This includes Super Mario Odyssey, Mario+Rabbids Kingdom Battle and Pokken Tournament DX. In Super Mario Odyssey they have a new mode that allows players to hide balloons for other players to find. Nintendo Revealed two new Pokemon for Pokken Tournament; the two new Pokemon are Blastoise and Aegislash. The DLC for Mario + Rabbids is a new story mode that includes Donkey Kong.
I am really looking forward to Mario Tennis Ace and Kirby Star Allies. It will be great to take these full fledged console games on the go! It is interesting to see the story mode return to Mario Tennis. What games are you looking forward to playing on the Nintendo Switch?
Posted on January 12, 2018 January 12, 2018 Categories NintendoTags nintendo direct mini, nintendo switch games, video gamesLeave a comment on Surprise Nintendo Direct Mini
Nintendo Delivers
Nintendo had a bevy of announcements and updates today. They showed off what was new in Pokemon Ultra Sun and Ultra Moon. The game will have new forms, new areas to explore and new bonuses. Nintendo showed off more 3ds content than I expected. They announced a new Mario Party game collection that will include the top 100 mini-games. I think this is pretty cool, although it should be for the Switch. Playing Mario Party on the 3ds is fun, but the game is really built for the TV. They also showed off Kirby: Battle Royale, Yo-Kai Watch 2, Minecraft for 3ds, Metroid Samus Returns, Apollo Justice: Ace Attorney, Fire Emblem Warriors for 3ds and a bunch of Atlas RPGs. It seems like Minecraft is on every system now. Nintendo also showed off their Pokemon 2DS and Orange 2DS. It’s great that Nintendo is still supporting the 3DS. What announcements did you like for the 3DS?
The star of the show was Super Mario Odyssey. Nintendo showed us the new snow world and the power moons that you need to collect. They also showed us a bunch of new footage. I can’t wait to get my hands on this game when it comes out on October 27th. Nintendo also showed us a Switch bundle that includes Super Mario Odyssey.
Nintendo showed off a variety of other Switch titles. This included Xenoblade Chronicles 2, Octopath Traveler, Rocket League, Fire Emblem Warriors, Skyrim, Doom, Wolfenstein 2, NBA 2K18, Fifa 18, WWE 2K18, Dragon Quest Builders, Pokken Tournament DX, and Kirby: Star Allies. I am looking forward to playing Rocket League on the go. I feel like it will suit the system well. Nintendo also announced updates for Arms and Splattoon 2. The new character Lola Pop is out for Arms. There weren’t any huge suprises in this direct, but I think it was a solid direct none the less. What are you looking forward to on the Nintendo Switch?
Posted on September 15, 2017 September 15, 2017 Categories NintendoTags Mario Odyssey, Nintendo, nintendo directLeave a comment on Nintendo Delivers
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This is a promo message area
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Biden Announces Cancer Moonshot Initiative at ASCO Annual Conference
by Joseph Bryant | Tuesday, July 19, 2016 | New Orleans, Chicago and Public Health
Vice President Joe Biden has been crisscrossing the country to push the federal government's overall cancer "moonshot" initiative, speaking at cancer centers and addressing oncology professional societies, making the case for breaking down existing silos to accelerate cancer research and delivery.
Earlier this year, in April, Biden spoke to more than 4,000 attendees at the American Association for Cancer Research's annual meeting in New Orleans, and two weeks ago brought his message to an audience of about 6,000 at the American Society of Clinical Oncology's (ASCO) annual meeting held in Chicago. Biden's theme at ASCO paralleled that of the annual meeting.
"This year, [ASCO's theme] is harnessing the collective wisdom of oncologists around the world to put patients at the center of research and care. That's exactly what I'm trying to do in the cancer moonshot, and it matters." noted Biden.
In addition to reiterating moonshot's critical priorities, Biden noted his vision of making data-sharing a reality by stressing the importance of developing a new mindset, while acknowledging ASCO's CancerLinQ project, and mentioned a new initiative launched that day by the NCI -- the Genomic Data Commons.
Prior to Biden’s address, there already existed two ASCO events related to the moonshot initiative: a press briefing dealing with critical priorities for the initiative, focusing on ASCO's involvement, and a panel discussion featuring members of the National Cancer Advisory Board's Blue Ribbon Panel, during which audience members were asked to submit ideas about the initiative.
In a subsequent press briefing, ASCO's CEO Allen S. Lichter, MD, chief medical officer Schilsky, and CancerLinQ medical director Robert S. Miller, MD, Blue Ribbon panelist Deborah Mayer, PhD, RN (who also appeared at the earlier panel discussion), and CancerLinQ CEO Kevin Fitzpatrick, who served as moderator, collectively underscored the final point.
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Sports Supplements For Better Metabolic Flexibility and Performance
Almost two years ago, this magazine ran an article entitled
"Supplements Target Ketogenesis and Metabolic Flexibility for Sports and Health."1 (June 2016) Last month there was a review of the state of caloric restriction / fasting and ketogenic diets today. However, many readers have little interest in either caloric restriction or ketogenic diets as lifestyle choices. Both of these approaches are difficult to follow even if being utilized for specific health purposes. Nevertheless, their basic principles have application to general health and to athletics. The foremost impediment to taking advantage of these approaches was laid out in the 2016 article.
A major problem in achieving keto-adaptation by diet alone is that most individuals who have been raised on Western-style diets can take six months or more to make the shift and this shift becomes ever more difficult as we age. Studies examining the role of carbohydrates in the metabolism with roughly 30 year old males in good physical condition have revealed, for instance, that even transitioning from a high glycemic index diet to a low glycemic index diet while maintaining the same ratio of carbohydrate, fat and protein can take more than four weeks. Shifting to fatty acid metabolism for energy can be difficult.
For most of us, the issue is whether a moderate change in diet accompanied by a judicious utilization of special foods and dietary supplements can achieve the goals usually associated with caloric restriction, fasting and ketogenic diets. Fortunately, the answer for the preponderance of readers is "yes." Both for anti-aging purposes and for athletics, metabolic flexibility likely can be achieved through approaches within the reach of almost everyone. The goal is not to be ketogenic all the time, but to be able to metabolize ketones and free fatty acids routinely and easily. For a nice introduction to the distinction, readers might visit the blog entitled "Ketogenesis, Measuring Ketones, and Burning Fat vs Being in Ketosis."2
Previously in these pages, it was noted that consuming too little protein presents issues, but, likewise, too much protein in the diet, meaning above roughly 30 percent of calories, defeats a major goal of caloric restriction, which is to not just reduce circulating insulin, but also to avoid elevating insulin-like growth factor-1 (IGF-1). Although those not trained in nutrition seldom realize this, protein sources can be used for gluconeogenesis, which is to say, to produce glucose from, non-carbohydrate sources. It is not just consuming too little fat and too much carbohydrate or too much of these two together with too little protein that defeat the aims of an anti-aging diet.
The recent Prospective Urban Rural Epidemiology (PURE) study followed 135,335 adults in eighteen countries for over seven years with respect to morbidity and mortality in terms of cardiovascular disease, strokes and non-cardiovascular disease mortality as correlated with the effects of nutrients.3 In an interview, Dr. Mashid Dehghan, the lead author, reported that Participants were categorized into quintiles of nutrient intake (carbohydrate, fats, and protein) based on percentage of energy provided by nutrients. We assessed the associations between consumption of carbohydrate, total fat, and each type of fat with cardiovascular disease and total mortality.
As noted by the researchers, their results flatly contradict decades of nutritional advice: High carbohydrate intake was associated with higher risk of total mortality, whereas total fat and individual types of fat were related to lower total mortality. Total fat and types of fat were not associated with cardiovascular disease, myocardial infarction, or cardiovascular disease mortality, whereas saturated fat had an inverse association with stroke. Global dietary guidelines should be reconsidered in light of these findings.
In the PURE study, those who consumed at least 35 percent of their calories from fat were 23 percent less likely to die than those who consumed only 10 percent or less as fat. According to PURE findings, the higher the fat intake, the less the chance of stroke. Those who consumed 77 percent of their calories as carbohydrates were 28 percent more likely to die than those who consumed less than 46 percent as carbohydrates. The conclusion of the study? "In a nutshell, a healthy diet based on the PURE results would be rich in fruits, beans, seeds, vegetables, and fats, include dollops of whole grains, and be low in refined carbohydrates and sugars."
The observant reader who takes the time to look at the PURE study's findings will quickly realize that the traditional reliance on "markers" such as blood LDL-cholesterol levels—markers long used to argue against the inclusion saturated fats any large amount of fats in general in the diet as well to promote carbohydrate consumption— does not correspond well with the actual endpoints of morbidity and mortality. This does not mean that the PURE diet needs to be ketogenic. To quote from the TotalHealth 2016 article, As admitted by Ben Greenfield, a serious triathlete who was tested with regard to the ergogenic benefits of a ketogenic diet, "after the study at University of Connecticut, I personally quit messing around with ketosis and returned to what I considered to be a more sane macronutrient intake of 50-60% fat, 20- 30% protein, 10-30% carbohydrate."4
As a practical matter, a more normal diet with supplements might look like this:
The diet should not be high in simple sugars, fructose or refined carbohydrates. For non-athletes and those looking primarily to increase metabolic flexibility, the diet should resemble a modified Sears Diet, meaning approximately 20 - 30 percent protein, 30 - 40 percent carbohydrate and 30 - 40 percent fat. For athletes and individuals who seriously want to initiate and maintain a fat-adapted diet, Ben Greenfield's suggestion is more in order: "50-60% fat, 20-30% protein, 10-30% carbohydrate."
Those who want to achieve most of the benefits of a ketogenic diet without undergoing the grueling restrictions normally involved (limitations not just on carbohydrate intake, which are extreme, but also on protein intake) should consider the fact that ketone bodies supply 2–6 percent of the body's energy requirements after an overnight fast (no eating at bedtime) with the higher figure reflecting a longer period without eating. After three days of fasting, 30–40 percent of energy needs are met by endogenously produced ketones. Such facts, again, lead to at least two possibilities aside from caloric restricted and ketogenic diets. First, will consuming exogenous ketones as esters or salts provide the same benefits as special diets? Second, is there a role for dietary supplements in delivering these benefits?
Ketones (Acetoacetate and β-hydroxybutyrate) Esters and Salts?
The new kid on the block in anti-aging and sports supplements is oral ketones, including a ketone ester (D-beta-hydroxybutyrate and D 1,3-butanediol) sports drink and ketone salts, typically beta-hydroxybutyrate bound to calcium, magnesium, potassium or sodium. A limited body of research indicates that such supplements may improve very long-duration endurance performance, but relatively little is known about their impact on short-duration and high-intensity workouts. Likewise, it is unclear that supplementation with ketones delivers the same benefits as adaptation to a ketogenic diet.
As one can learn from a variety of sources, "ketone bodies are three water-soluble molecules that are produced by the liver from fatty acids during periods of low food intake (fasting), carbohydrate restrictive diets, starvation and prolonged intense exercise… These ketone bodies are readily picked up by the extra-hepatic [outside the liver] tissues, and converted into acetyl-CoA which then enters the citric acid cycle and is oxidized in the mitochondria for energy. In the brain, ketone bodies are also used to make acetyl-CoA into long-chain fatty acids."5
In the liver, metabolism of fatty acids for energy, as opposed to ketone bodies, works in conjunction with a normal pattern of activity in the mitochondria, including the citric acid cycle. Ketone bodies are formed when there is not enough glucose from either carbohydrates, including glycogen, or the breakdown of protein to fuel the cycle. Technically, the supply of oxaloacetate is exhausted, at which point the liver produces and exports ketone bodies to tissues that can metabolize ketones fully. In starvation and under very low carbohydrate intake accompanied by restrained protein intake, ketone bodies supply up to 50 percent of the energy requirements for most body tissues and up to 70 percent of the energy required by the brain. The blog mentioned above provides a nice diagram of the cellular steps involved in ketone formation. The author also helpfully points out:
As I have written about eight hundred times in other posts, you do not need to be generating high levels of ketones to be metabolizing fat. The body does not operate in a binary system where the two choices are:
(1) Maintain deep ketosis …or…
(2) Become obese
Just because you're not in ketosis doesn't mean you're somehow not metabolizing fat so that the only other possible destination for it is to be stored.6
Ketone esters and salts can be ingested in an attempt to mimic a ketogenic state and work by elevating blood ketone levels to force the burning fat as fuel while interfering with certain other glycogen-related metabolic pathways. Whether supplements are the equivalent of a ketogenic diet in terms of benefits has been tested in humans only to a limited extent. In animal trials, they are not entirely equivalent and this appears also to be the case in humans. Let's start first with the animal experiments. The positive finding is that a 28-day administration of five ketone supplements on blood glucose, ketones, and lipids in male Sprague– Dawley rats caused a rapid and sustained elevation of beta-hydroxybutyrate and a reduction of blood glucose.7 No doubt, this represented a shift in the energy source to make use of the ingested ketones.
However, in a comparative trial of a ketogenic diet, ketone supplementation and control diet examining both control and chronic stress conditions, results differed with the intervention. Chronic experiments showed that under control conditions, only the ketogenic diet resulted in pronounced metabolic alterations and improved performance in the novel object recognition test and only the ketogenic diet prevented stress-induced deficits at the end of the trial and improved certain other aspects of performance. The advantage was to the ketogenic diet rather than supplementation in the areas of blood glucose, insulin and overall fat metabolism.8 Ketone supplements in animal models do indeed provide benefits, but not at the level of diet-induced endogenous production.
Thanks to recently published clinical trials, in the area of human athletic performance there now is evidence as to the limitations of ketone supplements. In one study, ten healthy adult males with similar athletic abilities and body mass indices fasted and then consumed either beta-hydroxybutyrate ketone salts or a matched placebo in a randomized order followed by a cycling time trial. Power output on the day participants consumed ketone salts was seven percent lower than on the day they consumed the placebo. As observed by study co-author Jonathan Little, assistant professor in University of British Columbia's (UBC) Okanagan's School of Health and Exercise Sciences, "Elevated blood ketones seem to inhibit the body's use of glycogen, the stored form of glucose, and favours burning fat instead."9,10 A previous study utilizing ketone esters (573 mg/kg athlete body weight) in conjunction with carbohydrate consumption had positive findings of better performance in cycling to exhaustion trials.11
The authors of both studies seem to agree that the ingestion of ketones leads to nutritional ketosis that alters the hierarchy of fuel substrate usage during exercise and it is clear that as the intensity of exercise increases, the demand for carbohydrate as an energy source increases. The ketone salt trial tested shorter and higher intensity training versus the longer period tested in the ketone ester trial, hence these were not entirely apple-to-apple trials. In addition, the ketone ester trial tested roughly 30 grams of ketone ester taken in conjunction with carbohydrate leading to significant benefit versus carbohydrate alone. However, bicycle ergometer time trial performance was only approximately two percent greater using the ketone ester plus carbohydrate versus carbohydrate alone "representing a modest increase in physical capacity in these highly trained athletes, despite significant changes in muscular metabolism." This finding, once again, indicates the difficulty of fully substituting ketones for glycogen-dependent aspects of muscle performance.
The latest studies continue the trend from above. Ingested ketones, for instance, as esters, impaired performance in elite cyclists in ˜31 kilometer laboratory-based time trials on a cycling ergometer programmed to simulate the 2017 World Road Cycling Championships course.12 Achieving overall fat / keto adaptation via dietary means is more successful. Nevertheless, aside from the difficulty in following such diets, keto adaptation to a low carbohydrate, high fat diet requires time. Three weeks clearly is not sufficient even in highly trained athletes such as elite endurance walkers.13 Ten weeks in trained athletes appears to be on the margin, improving feelings of wellbeing, but not performance.14 At least insofar as attested in published trials, a full 12 weeks or more of adaptation is required even in the relatively young (20 subjects, 33 ± 11 years) and vigorous to achieve superior endurance results in comparison to a high carbohydrate diet.15
The above findings lead this author to the observation that although ketone ester-induced ketosis may increase metabolic flexibility during exercise by reducing glycolysis and increasing muscle fat oxidation, the benefits during shorter time periods and/or higher VO2/max demands are either not great or actually negative. Metabolic flexibility in the ester trial, such as it was, required the coingestion of carbohydrate. Without the co-ingestion of carbohydrate, as demonstrated in the other ketone trials (both salt and ester), there was a significant inhibition of the ability to access glycogen stores for energy upon demand.
Metabolic Fitness Supplements
Before looking at individual supplements, it is important
to understand that nutrients that aid metabolic fitness generally fulfill a number of requirements, among them the following:
It is helpful to support fat metabolism directly such as through improved transport of fatty acids into the mitochondria for oxidation.
Insulin sensitivity must be improved and maintained and insulin levels kept low.
The release of fatty acids from fat cells likely is less important than is dis-inhibiting fatty acid metabolism. The first is accomplished with caffeine, yet often with a downside such as increased cortisol levels, hence alternatives to caffeine and other similar stimulants are needed.
Inclusion of substances that actively promote fatty acid oxidation is important to help kick-start the body's ability to metabolize fats.
Excessive gluconeogenesis by the liver (creation of glucose from glycogen in response to the release of glucagon) should be inhibited to promote fatty acid oxidation as the alternative.
With diets that are heavy in alcohol and fat, potential "reverse" effects must be prevented.
The sources of useful supplements are not generic and this should be kept in mind because different production methods lead to different products with different results. The following discussion reviews key nutrients that fulfill one or more of the above requirements.
Potassium-Magnesium Hydroxycitrate
Very few athletes are aware of the benefits of (–)-hydroxycitric acid (HCA) for sports despite some impressive findings in terms of greater endurance and faster recovery plus reduced inflammation. This is because early trials—there were several large ones—failed to produce benefits for reasons that, in retrospect, are obvious. First, calcium HCA and calcium-containing HCA salts exhibit very poor uptake and poor results in comparative trials.16,17,18 To this should be added the "food effect," meaning the finding that consuming food within 30 minutes of ingesting HCA typically reduces uptake by approximately 60 percent. HCA salts under normal delivery never exhibit more than lackluster bioavailability, hence any reduction of that already modest uptake into the system leads to extremely poor results. A third factor is that even seemingly nearly identical HCA salts (as tested by standard high performance liquid chromatography / HPLC) produced by slightly differing production techniques can exhibit up to 10-fold differences in bioavailability.19 Notably lacking in the research literature is any attempt to determine cellular uptake, an issue separate from bioavailability. Published research simply assumes that all uptake issues can be reduced to bioavailability, meaning blood levels, an assumption proven to be invalid with a number of nutritional substances, such as coenzyme Q10.
One way around these uptake problems with HCA is by means of a special liquid delivery. HCA salts normally are not stable in ready-to-drink formats and break apart to yield what is known as a lactone. The HCA lactone leads to good uptake—bioavailability—but little or no benefits because the molecule exhibits the wrong shape.20 A recently issued US patent describes a method that not only stabilizes HCA salts in liquid, but also dramatically improves their bioavailability and physiologic efficacy.21
Properly produced and delivered HCA can lead to striking improvements in early fat utilization for energy, glycogen sparing and increases in endurance. This is in part because HCA helps to control the muscle's selection of fuels, an experimental finding from twenty years ago.22 More recently, using mice as the model, HCA ingestion for 13 days was found to increase fat oxidation and improve endurance exercise time to fatigue by 43 percent compared to a placebo.23 Chronic HCA ingestion alters fuel selection rather than the simple release of fat from stores as is true of lipolysis per se, i.e., the mechanism for HCA is not the same as with caffeine, capsaicin, etc. Second, the combination of HCA plus L-carnitine improves glycogen status in liver and various muscle tissues versus placebo in exercised-trained rodents. Readers will recall that glycogen-related issues bulk large in the performance failings of ketogenic diets and ketone supplements.
What about HCA ingestion in humans? Similar positive endurance results were found by the same laboratory both with untrained men and women and with trained athletes as found in the animal tests. The following trial was conducted in trained athletes leading to significant improvements in endurance:
Subjects [n = 6] were administered … HCA or placebo as a control (CON) for 5 d, after each time performing cycle ergometer exercise at 60% VO2max for 60min followed by 80% VO2max until exhaustion.24
Under the conditions of the trial, time to exhaustion at 80 percent VO2max went from approximately six minutes to approximately 8.5 minutes, which is a remarkable level of improvement. Lactate levels were lower. In evaluating the results, it must be observed that the earlier animal trials indicated that there is a greater shift in metabolism if the ingestion period lasts longer. But note clearly: the HCA salt used in these trials was a pure synthesized trisodium hydroxycitrate, not the usual HCA available as a dietary supplement.25
Another benefit from HCA is as much as a 100 percent improvement in glycogen repletion in muscle after exercise when a post-workout snack is consumed.26
Mango Leaf Extract and Caffeic Acid Enhance HCA's Ability to Improve Fat Metabolism
An issue that almost always is ignored with HCA is that under conditions of accelerated use of fat for energy, such as during fasting or ketogenic diets, there is a cycle that can undermine the compoundfs effects on fat metabolism by activating inside cells the substance acetyl-CoA carboxylase.27 Two compounds that help to prevent this and actually improve fatty acid oxidation are caffeic acid and mangiferin (a constituent of mango leaf).
Caffeic acid is interesting for a number of reasons. For current purposes, it has been shown to improve the ability to metabolize fats for energy and also to promote the ability of glucose to enter cells, i.e., it is insulin sensitizing. In terms of HCA, caffeic acid helps block the actions of acetyl-CoA carboxylase.28 This means that it helps to block the impact of high alcohol intake and high fat intake or fasting on HCA, thus allowing HCA to perform the function of disinhibiting fatty acid metabolism via β-oxidation as mentioned above.
Mangiferin, the primary active component in mango leaf extract, is even more significant than is caffeic acid. With regard to HCA, mangiferin, like caffeic acid, inhibits acetyl- CoA carboxylase. However, matters do not stop there. In various in vitro and animal trials, mangiferin increased fatty acid oxidation. A major finding is that the compound does the same, and safely, in human beings. Overweight patients with hyperlipidemia (serum triglyceride ≥ 1.70 mmol/L, and total cholesterol ≥ 5.2 mmol/L) were included in a double-blind randomized controlled trial. Participants were randomly allocated to groups, either receiving mangiferin (150 mg/day) or an identical placebo for 12 weeks. As reported in the published study,29
A total of 97 participants completed the trial. Compared with the placebo control, mangiferin supplementation significantly decreased the serum levels of triglycerides and FFAs, and insulin resistance index. Mangiferin supplementation also significantly increased the serum levels of mangiferin, high-density lipoprotein cholesterol, L-carnitine, β-hydroxybutyrate, and acetoacetate, and increased lipoprotein lipase activity.
The increase in β-hydroxybutyrate and acetoacetate as well as lipoprotein lipase activity is a clear indication that mangiferin improves the availability of stored fats and promotes the oxidation of these fats for the production of energy as they became available.
Asparagine, Malate and Aspartates for Energy and Endurance
Some of the best supplements for health and sports have, as it were, slipped under the radar over the years. We tend to be attracted to whatever is "new" to the point of overlooking that these new items often are not actually novel, just older concepts dressed up in new terminology. A good example of this is the great fanfare given to the recent "discoveries" involving nicotinamide riboside. (Caloric Restriction, Fasting and Nicotinamide Riboside TotalHealth Feb 2015)30 Proffered benefits include anti-aging effects, better energy metabolism and endurance.31 Strikingly, both the mechanisms involved and the benefits, upon closer examination, look remarkably similar to the benefits associated with what is known as the malate-aspartate shuttle. The anti-aging benefits, for instance, are similar to those associated with the Chinese herb rock lotus, which activates the enzyme (malate dehydrogenase) linked with this shuttle. (Uncovering the Longevity Secrets of the ROCK LOTUS TotalHealth April 2010)32
For the hard science minded, the malate/aspartate shuttle is a principal mechanism for the movement of reducing equivalents from the cytoplasm to the mitochondria. In other words, this mechanism keeps energy as electrons flowing from the cytoplasm of the cell into the mitochondria and supports the production of adenosine triphosphate (ATP), the basic energy unit of the body. Ketones can play a similar role. As expressed in a recent paper, "cellular energy production depends on the metabolic coenzyme nicotinamide adenine dinucleotide (NAD), a marker for mitochondrial and cellular health. Furthermore, NAD activates downstream signaling pathways (such as the sirtuin enzymes) associated with major benefits such as longevity and reduced inflammation... [a ketogenic diet] will increase the NAD+/NADH ratio."33 (NAD exists in oxidized and reduced forms, NAD+ and NADH.) This process is exactly what the recent discoveries regarding nicotinamide riboside are about. The shuttle also is involved in replenishing oxaloacetate, which was mentioned above with regard to ketogenesis and the Krebs/Citric Acid Cycle. Part of the role of oxaloacetate is shown in the diagram.
Now it just so happens that malic and aspartic acid (the "salts" are termed malate and aspartate) are components of this movement of energy. Malate, aspartate and the compound asparagine are known as oxaloacetate precursors. Many athletes use citrulline malate to help promote performance and reduce fatigue thinking that it is the citrulline that is active although, in fact, it is the malate. For instance, in an animal trial a month of supplementation with L-malate increased swimming time endurance by between 26.1 and 28.5 percent.34 The researchers observed the activities of cytosolic and mitochondrial malate dehydrogenase were significantly elevated in the L-malate-treated group compared with the control group.
As pointed out in the TotalHealth article on the rock lotus, the malate dehydrogenase enzyme takes a period of time to be increased in the cell. A number of acute trials of, for instance, aspartates in athletes, compounds that affect the same shuttle mechanism, failed, but this should have been expected due to basic physiology and one wonders why those researchers even bothered. Under conditions of moderate exertion, supplementation with asparagine and aspartate plus L-carnitine increased time to exhaustion by approximately 40 percent.35 In another animal trial, this time with intense exercise and only the two amino acids, the supplemented group showed higher exercise time, lower blood lactate concentration and a decreased the rate of glycogen degradation compared to control leading to the conclusion that "supplementation may increase the contribution of oxidative metabolism in energy production and delay fatigue during exercise performed above the AT [anaerobic threshold]."36
To be sure, there are skeptics regarding magnesium—potassium aspartates for use as ergogenic aids.37 However, the proposed mechanisms of action until recently have been wrong, the time frame for supplementation (acute rather than chronic), the amounts supplemented, etc., typically have been quite wide of the mark. The key mechanism of action involves the shuttle and oxaloacetate. Interestingly, this mechanism also promotes the proper metabolism of that great enemy of athletes, lactic acid. Lactic acid actually can be converted back into an energy source during exercise. As Ben Greenfield explains things in a wonderful post,38 A significant rate limiting step of converting lactic acid into glucose is the conversion of the molecule Nicotinamide Adenine Dinucleotide (NAD) into Nicotinamide Adenine Dinucleotide Hydrogenase (NADH). So what does this have to do with oxaloacetate? In studies, acute oxaloacetate exposure enhances resistance to fatigue by increasing NAD to NADH conversion and allowing lactic acid to get recycled and converted to glucose at a much higher rate.39
Oxaloacetate is notoriously unstable and difficult to supplement orally. A mixture of its precursors (aspartate salts, asparagine and a malate source) plus an activator of the malate dehydrogenase enzyme (rock lotus) supplemented over a period of time (three to four weeks) is a better way to achieve desired benefits. Finally, another benefit of a mixture of malate and aspartate is that the malate-aspartate shuttle plays a role in the regeneration of L-arginine and the production of nitric oxide.40
Move over, NO (nitric oxide) supplements! Altering muscle fuel selection and increasing the anaerobic threshold are the hallmarks of metabolic flexibility in sports. Greater utilization of stored fatty acids for fuel, reduced lactate accumulation and better recycling, enhanced glycogen stores and an elevation of VO2max before the body's limited stores are called upon without an impairment of carbohydrate utilization is an ideal situation. It is not clear that fulfilling this goal demands artificially elevating blood ketone bodies, either through diet or supplements. Instead, maximizing the efficiency of energy pathways that make use of stored fatty acids and the malate-aspartate shuttle would seem to be not just sufficient, but preferred. Chronic HCA ingestion alters muscle fuel selection and improves glycogen stores, especially in conjunction with L-carnitine. Caffeic acid enhances these actions, as does mangiferin from mango leaf in ways that have been demonstrated in humans to augment the metabolism of both fatty acids and carbohydrates leading to elevated energy production. The malate-aspartate shuttle and the enzyme malate dehydrogenase support oxaloacetate recycling and the efficient operation of the citric acid cycle to sustain fatty acid oxidation and the reconversion of lactic acid to glucose for use as fuel by the muscles. Surely a clincher for this approach is that it promises health and anti-aging benefits, not just improvements in athletic performance.
Supplements Target Ketogenisis and Metabolic Flexibility TotalHealth Magazine
Measuring Ketones
Dehghan M, Mente A, Zhang X, Swaminathan S, Li W, Mohan V, Iqbal R, Kumar R, Wentzel-Viljoen E, Rosengren A, Amma LI, Avezum A, Chifamba J, Diaz R, Khatib R, Lear S, Lopez-Jaramillo P, Liu X, Gupta R, Mohammadifard N, Gao N, Oguz A, Ramli AS, Seron P, Sun Y, Szuba A, Tsolekile L, Wielgosz A, Yusuf R, Hussein Yusufali A, Teo KK, Rangarajan S, Dagenais G, Bangdiwala SI, Islam S, Anand SS, Yusuf S; Prospective Urban Rural Epidemiology (PURE) study investigators. Associations of fats and carbohydrate intake with cardiovascular disease and mortality in 18 countries from five continents (PURE): a prospective cohort study. Lancet. 2017 Nov 4;390(10107):2050–62.
How To Get Into Ketosis
Ketone_Bodies
Measuring Keytones
Kesl SL, Poff AM, Ward NP, Fiorelli TN, Ari C, Van Putten AJ, Sherwood JW, Arnold P, D'Agostino DP. Effects of exogenous ketone supplementation on blood ketone, glucose, triglyceride, and lipoprotein levels in Sprague-Dawley rats. Nutr Metab (Lond). 2016 Feb 4;13:9.
Brownlow ML, Jung SH, Moore RJ, Bechmann N, Jankord R. Nutritional Ketosis Affects Metabolism and Behavior in Sprague-Dawley Rats in Both Control and Chronic Stress Environments. Front Mol Neurosci. 2017 May 15;10:129.
Ketone sports supplements: Good for athletic performance or not?
O'Malley T, Myette-Cote E, Durrer C, Little JP. Nutritional ketone salts increase fat oxidation but impair high-intensity exercise performance in healthy adult males. Appl Physiol Nutr Metab. 2017 Oct;42(10):1031–5.
Cox PJ, Kirk T, Ashmore T, Willerton K, Evans R, Smith A, Murray AJ, Stubbs B, West J, McLure SW, King MT, Dodd MS, Holloway C, Neubauer S, Drawer S, Veech RL, Griffin JL, Clarke K. Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes. Cell Metab. 2016 Aug 9;24(2):256–68.
Leckey JJ, Ross ML, Quod M, Hawley JA, Burke LM. Ketone Diester Ingestion Impairs Time-Trial Performance in Professional Cyclists. Front Physiol. 2017 Oct 23;8:806.
Burke LM, Ross ML, Garvican-Lewis LA, Welvaert M, Heikura IA, Forbes SG, Mirtschin JG, Cato LE, Strobel N, Sharma AP, Hawley JA. Low carbohydrate, high fat diet impairs exercise economy and negates the performance benefit from intensified training in elite race walkers. J Physiol. 2017 May 1;595(9):2785–2807.
Zinn C, Wood M, Williden M, Chatterton S, Maunder E. Ketogenic diet benefits body composition and well-being but not performance in a pilot case study of New Zealand endurance athletes. J Int Soc Sports Nutr. 2017 Jul 12;14:22.
McSwiney FT, Wardrop B, Hyde PN, Lafountain RA, Volek JS, Doyle L. Keto-adaptation enhances exercise performance and body composition responses to training in endurance athletes. Metabolism. 2017 Dec 2. pii: S0026-0495(17)30328-1.
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Clouatre D, Preus HG. Potassium Magnesium Hydroxycitrate at Physiologic Levels Influences Various Metabolic Parameters and Inflammation in Rats. Current Topics in Nutraceutical Research 2008;6(4): 201–10.
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United States Patent 9,789,076 Bolus Dose of Hydroxycitric Acid with Glycerol
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Ishihara K, Oyaizu S, Onuki K, Lim K, Fushiki T. Chronic (-)-hydroxycitrate administration spares carbohydrate utilization and promotes lipid oxidation during exercise in mice. J Nutr. 2000 Dec;130(12):2990–5.
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Triscari J, Sullivan AC. Comparative effects of (--)-hydroxycitrate and (+)-allo-hydroxycitrate on acetyl CoA carboxylase and fatty acid and cholesterol synthesis in vivo. Lipids. 1977 Apr;12(4):357-63.
Tsuda S, Egawa T, Ma X, Oshima R, Kurogi E, Hayashi T. Coffee polyphenol caffeic acid but not chlorogenic acid increases 5'AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscle. J Nutr Biochem. 2012 Nov;23(11):1403-9.
Na L, Zhang Q, Jiang S, Du S, Zhang W, Li Y, Sun C, Niu Y. Mangiferin supplementation improves serum lipid profiles in overweight patients with hyperlipidemia: a double-blind randomized controlled trial. Sci Rep. 2015 May 19;5:10344.
Caloric Restriction Fasting and Nicotinamide Riboside TotalHealth Magazine
Dellinger RW, Santos SR, Morris M, Evans M, Alminana D, Guarente L, Marcotulli E. Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study. NPJ Aging Mech Dis. 2017 Nov 24;3:17.
Uncovering the Longevity Secrets of the ROCK LOTUS TotalHealth Magazine
Elamin M, Ruskin DN, Masino SA, Sacchetti P. Ketone-Based Metabolic Therapy: Is Increased NAD+ a Primary Mechanism? Front Mol Neurosci. 2017 Nov 14;10:377.
Wu JL, Wu QP, Huang JM, Chen R, Cai M, Tan JB. Effects of L-malate on physical stamina and activities of enzymes related to the malateaspartate shuttle in liver of mice. Physiol Res. 2007;56(2):213–20.
Lancha AH Jr, Recco MB, Abdalla DS, Curi R. Effect of aspartate, asparagine, and carnitine supplementation in the diet on metabolism of skeletal muscle during a moderate exercise. Physiol Behav.1995 Feb;57(2):367–71.
Marquezi ML, Roschel HA, dos Santa Costa A, Sawada LA, Lancha AH Jr. Affect of aspartate and asparagine supplementation on fatigue determinants in intense exercise. Int J Sport Nutr Exerc Metab. 2003 Mar;13(1):65–75.
Trudeau F. Aspartate as an ergogenic supplement. Sports Med. 2008;38(1):9–16.
Underground Training Tactics For Enhancing Endurance – Part 2
Nogueira, L., Hogan, D., & Hogan, M. (n.d.). Acute oxaloacetate exposure enhances resistance to fatigue iin vitro mouse soleus muscle. (2011). The FASEB Journal, (25), 1104.5.
Hou E, Sun N, Zhang F, Zhao C, Usa K, Liang M, Tian Z. Malate and Aspartate Increase L-Arginine and Nitric Oxide and Attenuate Hypertension. Cell Rep. 2017 May 23;19(8):1631–39.
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Home /Culture/Features
Dying to go home: The past and future of the Lhotshampa of Bhutan
Half an hour outside of the small dusty town of Damak in eastern Nepal is a tiny bamboo village. This town is almost 30 years…
UMaine Museum of Art Bangor opens its Winter Exhibitions. Photo by Antyna Gould. Culture
UMMA winter exhibition embraces interpretation
Every year, the University of Maine Museum of Art (UMMA) attempts to bring modern and contemporary art to central Maine by highlighting 12 original exhibitions.…
Bounding Towards Adventure
Nestled comfortably on the southeast side of the University of Maine campus in an old, white barn, Maine Bound Adventure Center makes its home.…
Homecoming brings students and alum together to celebrate the University Of Maine community. Photo by Matt Lavoie. Culture
Royalty makes it’s return to UMaine
This weekend, Oct. 26-28, the University of Maine community gathered for one of it’s longest and proudest traditions: homecoming. Every year students and alumni…
9 reasons to study the humanities
In the past decade, education has been heavily STEM (science, technology, engineering and mathematics) centered. A core effort of the Obama Administration, the White House…
Photo from Taylor Abbott Culture
Siempre vida España
May 25, 2018: The day that I embarked on my biggest adventure yet. For the first time in my life, I had the opportunity to…
10 Halloween Costumes That Won’t Offend Anyone
It is that time of year, we need to start thinking about what to wear on All Hallows’ Eve. It is very important to stay…
Gualla boys performing, photo courtesy of Cameron Goff. Culture
For the homies, by the homies: Portland’s Gualla Boys experience with hip-hop in Maine.
For Cameron Goff and Alex Girsch, hip-hop is much more than just a pastime. Their newest album “Righteous,” released on Aug. 12, has given them…
Maine Memes for Drunken Teens Facebook Banner. Photo courtesy of Takquan Parks. Culture
Student-run meme page gives students a platform to discuss real issues
In one corner of the internet, labeled as a “Study Group,” the UMaine Memes for Drunken Teens Facebook group discusses campus culture in an…
“Second Nature” by Selley Reed on display at UMMA until Dec 29. Photo courtesy of Olivia Shipsey. Culture
Shelley Reed’s “Second Nature” plays in the shadows
Running from Sept. 14 through Dec. 29, Shelley Reed’s “Second Nature” is one of three exhibitions currently on display in the University of Maine Museum…
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Posts Tagged ‘antonio valencia
Football fever is back
Tags: antonio valencia, chelsea, chris foy, community shield, cristiano ronaldo, epl, football, gabriel obertan, manchester united, michael owen, patrice evra, petr cech, sir alex ferguson, zoran tosic
So what if Manchester United lost the Community shield game to Chelski? We are still the Premiership champs and have also won the Champions League three times, something the Blues haven’t managed even once. Of course, there was Evra and his penalty kick. Makes me feel I coud guide the ball past Cech with a broken knee. But then there was also blind Mr. Chris Foy. It would be easy to argue about his decisions but it would be wise to say it was an evenly contested game that could have gone either way. Only a fool would play down United’s chances in the Premiership after this loss; the Shield after all only decides who gets to own up the initial bragging rights.
The Red Devils will definitely go into the league as favorites even without Ronaldo and Carlos Tevez. Sir Alex may not have shelled out £50 million on transfers, but Michael Owen, Gabriel Obertan and Antonio Valencia will be eager to prove themselves. The signing of Owen on a free transfer is probably the best move this season so far in the Premiership. He has so far hit top form in the pre-season games. An early introduction of Owen could have swinged United’s fortunes against Chelski. Ecuadorian Valencia is by no means Ronaldo, but his last season at Wigan was nothing short of exceptional. Then there is also the yet to be tested Zoran Tosic. He played a few games for the senior team last year but was largely involved in reserve fixtures.
I really can’t wait for the Premier League to start. I have already started making my presence felt in Fantasy Premier League games on various sites. Like any other Red Devils faithful, I too am praying for another successive title not just in England but also Europe.
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Louisiana Department of Justice
State Government | State Agencies
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Recent News About Louisiana Department of Justice View More
LOUISIANA DEPARTMENT OF JUSTICE: Student Loans to be Forgiven for Totally and Permanently Disabled Veterans
Mere weeks after petitioning the U.S. Department of Education to automatically forgive the student loans of veterans who became totally and permanently disabled in connection with their military service, Louisiana Attorney General Jeff Landry praised the Trump Administration for taking action to do just that.
LOUISIANA DEPARTMENT OF JUSTICE: Bipartisan Legislation to Protect Patients with Pre-Existing Conditions Becomes Law
The Health Care Coverage for Louisiana Families Protection Act, bipartisan legislation pushed by Attorney General Jeff Landry to protect patients with pre-existing conditions should federal courts continue to rule the Affordable Care Act unconstitutional, has become law in Louisiana.
LOUISIANA DEPARTMENT OF JUSTICE: SCOTUS Preserves Veterans Memorial, Attorney General Jeff Landry Praises Ruling
The United States Supreme Court issued a 7-2 ruling on Thursday protecting a memorial honoring World War I veterans in Maryland against a lawsuit aimed at forcing the State to tear down the historic cross.
From Legal Newsline
Litigious Louisiana municipalities the focus of Federalist Society event
By Kyla Asbury | 10 months ago
NEW ORLEANS (Legal Newsline) – The New Orleans Lawyers Chapter of The Federalist Society held an event at Galatoire's in New Orleans to discuss class action litigation on March 8.
LOUISIANA DEPARTMENT OF JUSTICE: Baton Rouge Man Indicted For Wire and Tax Fraud
U.S. Attorney Peter G. Strasser announced yesterday that WAYNE TRICHE, age 75, of Baton Rouge, was charged in a 38-count Indictment with wire fraud and tax fraud in violation of Title 18, United States Code, Section 1343 and Title 26, United States Code, Section 7206(1), respectively.
LOUISIANA DEPARTMENT OF JUSTICE: Bookkeeper Pleads Guilty To Failing To Declare More Than $700,000 In Stolen Money On Tax Return. Admits To Stealing Over Five Million from New Orleans Law Firm and Real Estate Company
U.S. Attorney Peter G. Strasser announced today that PEGGY NAGELE, age 65 of Thibodeaux, Louisiana pleaded guilty January 24, 2019 to a one count bill of information, charging her with violating Title 26, United States Code, Section 7206, making false statements on an income tax return.
Major Louisiana associations nominate 5th Circuit judges
Kyle S. Duncan and Judge Kurt D. Engelhardt belong in the Fifth Circuit Court of Appeals, according to three major Louisiana associations.
Northwestern State trying to collect on past due tuition
GRETNA — Northwestern State University is seeking more than $8,800 from a former student.
Jefferson Parish man allegedly owes university more than $4,000
GRETNA — A New Orleans university is seeking the balance on a past due account held by a Jefferson Parish man.
Woman allegedly owes University of New Orleans more than $1,300
GRETNA — The University of New Orleans is seeking damages for an open account that is in arrears for more than $1,300.
Orleans Parish woman allegedly owes university more than $7,000
NEW ORLEANS – A university is seeking more than $7,000 on unpaid student debt.
University of New Orleans seeking more than $3,000 from former student
GRETNA — The University of New Orleans claims that it is owed more than $3,000 from a former student.
Delgado Community College seeks unpaid tuition from former student
GRETNA — A community college claims that a student owes for classes she attended.
Louisiana's Landry elected vice president of National Association of Attorneys General
BATON ROUGE — Louisiana Attorney General Jeff Landry has been elected vice president of the National Association of Attorneys General (NAAG).
The University of Louisiana at Lafayette claims a student failed to pay for classes
NEW ORLEANS – A local university has filed suit against a former student it claims failed to pay for classes.
College claims former student allegedly failed to pay for classes
GRETNA – A community college claims a former student failed to pay for the classes in which he was enrolled.
Community college alleges former student failed to pay for classes
GRETNA – A community college claims that a student allegedly failed to pay after attending class there.
Jefferson Parish man allegedly didn't pay for college classes
GRETNA – A community college alleges a Jefferson Parish man has an unpaid balance equal to 13 credit hours of coursework.
Two Lincoln Parish Districts claim Police Jury does not accurately represent minority populations
RUSTON – A lawsuit has been filed against the Lincoln Parish Police Jury and its president alleging a lack of representation in two districts.
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news category created 16 October 2012 written by Mick Glossop
The First Q-Time Event
Upwards of 70 producers, engineers and musicians filled the room on Oct 15th 2012 at The Hospital Club in London’s Covent Garden for the first event in the new Q-Time series, chaired by BBC 6Music presenter, Tom Robinson.
The audience was enthralled and entertained by our panel of distinguished industry professionals; Alison Wenham, Andy Gill, Geoff Taylor, Hal Ritson and Martin Mills.
You can read a report here, published in PSN Europe online magazine.
MPG Full & Associate Members can log in and listen to the recording.
Topics discussed:
• In view of the low payments from Spotify to artists and producers, is the streaming of music online a viable model for the future distribution of recorded music?
• There is an increasing number of artists who are developing careers outside of the traditional framework, i.e. contracts with record companies and publishers. Does the panel view this as a welcome development or a threat to the existing structure?
• Major record companies are now insisting on 360 degree deals with their artists in an attempt to replace the revenues lost from diminishing record sales. Will the 360 degree deal save the music industry or is it just another form of exploitation?
• Do popular radio stations playlists represent their listeners preferences, those of the DJ’s & program producers or the ‘plugging’ activities of the record companies?
• What is the reaction of the panel to the recent approval of the sale of EMI Records?
• What do the members of the panel have to say to record producers and non-performing song-writers whose income and livelihood is undermined by the illegal downloading of music files?
• Do the members of the panel think that the music business would survive if Simon Cowell became the next UK prime minister?
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« The Semantic Web, Collective Intelligence and Hyperdata.
Semantic Web »
January 21, 2008 by Francisco Antonio Cerón García
Collective intelligence is a form of intelligence that emerges from the collaboration and competition of many individuals. Collective intelligence appears in a wide variety of forms of consensus decision making in bacteria, animals, humans, and computers. The study of collective intelligence may properly be considered a subfield of sociology, of business, of computer science, and of mass behavior — a field that studies collective behavior from the level of quarks to the level of bacterial, plant, animal, and human societies.
The above definition has emerged from the writings of Peter Russell (1983), Tom Atlee (1993), Pierre Lévy (1994), Howard Bloom (1995), Francis Heylighen (1995), Douglas Engelbart, Cliff Joslyn, Ron Dembo, Gottfried Mayer-Kress (2003) and other theorists. Collective intelligence is referred to as Symbiotic intelligence by Norman L. Johnson.
Some figures like Tom Atlee prefer to focus on collective intelligence primarily in humans and actively work to upgrade what Howard Bloom calls “the group IQ”. Atlee feels that collective intelligence can be encouraged “to overcome ‘groupthink‘ and individual cognitive bias in order to allow a collective to cooperate on one process—while achieving enhanced intellectual performance.”
One CI pioneer, George Pór, defined the collective intelligence phenomenon as “the capacity of human communities to evolve towards higher order complexity and harmony, through such innovation mechanisms as differentiation and integration, competition and collaboration.”[1] Tom Atlee and George Pór state that “collective intelligence also involves achieving a single focus of attention and standard of metrics which provide an appropriate threshold of action”. Their approach is rooted in Scientific Community Metaphor.
1 General concepts
3 Types of collective intelligence
4 Examples of collective intelligence
5 Mathematical techniques
6 Opposing views
7 Recent developments
[edit] General concepts
Howard Bloom traces the evolution of collective intelligence from the days of our bacterial ancestors 3.5 billion years ago to the present and demonstrates how a multi-species intelligence has worked since the beginning of life. [2]
Tom Atlee and George Pór, on the other hand, feel that while group theory and artificial intelligence have something to offer, the field of collective intelligence should be seen by some as primarily a human enterprise in which mind-sets, a willingness to share, and an openness to the value of distributed intelligence for the common good are paramount. Individuals who respect collective intelligence, say Atlee and Pór, are confident of their own abilities and recognize that the whole is indeed greater than the sum of any individual parts.[citation needed]
From Pór and Atlee’s point of view, maximizing collective intelligence relies on the ability of an organization to accept and develop “The Golden Suggestion”, which is any potentially useful input from any member. Groupthink often hampers collective intelligence by limiting input to a select few individuals or filtering potential Golden Suggestions without fully developing them to implementation.
Knowledge focusing through various voting methods has the potential for many unique perspectives to converge through the assumption that uninformed voting is to some degree random and can be filtered from the decision process leaving only a residue of informed consensus. Critics point out that often bad ideas, misunderstandings, and misconceptions are widely held, and that structuring of the decision process must favor experts who are presumably less prone to random or misinformed voting in a given context.
While these are the views of experts like Atlee and Pór, other founding fathers of collective intelligence see the field differently. Francis Heylighen, Valerie Turchin, and Gottfried Mayer-Kress view collective intelligence through the lens of computer science and cybernetics. Howard Bloom stresses the biological adaptations that have turned most of this earth’s living beings into components of what he calls “a learning machine”. And Peter Russell, Elisabet Sahtouris, and Barbara Marx Hubbard (originator of the term “conscious evolution”) are inspired by the visions of a noosphere–a transcendent, rapidly evolving collective intelligence–an informational cortex of the planet.
An early precursor of the concept of collective intelligence was entomologist William Morton Wheeler‘s observation that seemingly independent individuals can cooperate so closely as to become indistinguishable from a single organism. In 1911 Wheeler saw this collaborative process at work in ants, who acted like the cells of a single beast with a collective mind. He called the larger creature that the colony seemed to form a “superorganism”.
In 1912, Émile Durkheim identified society as the sole source of human logical thought. He argues in The Elementary Forms of Religious Life that society constitutes a higher intelligence because it transcends the individual over space and time. [3]
Collective intelligence, which has antecedents in Pierre Teilhard de Chardin‘s concept of “noosphere” as well as H.G. Wells‘s concept of “world brain,” has more recently been examined in depth by Pierre Lévy in a book by the same name, by Howard Bloom in Global Brain (see also the term global brain), by Howard Rheingold in Smart Mobs, and by Robert David Steele Vivas in The New Craft of Intelligence. The latter introduces the concept of all citizens as “intelligence minutemen,” drawing only on legal and ethical sources of information, as able to create a “public intelligence” that keeps public officials and corporate managers honest, turning the concept of “national intelligence” on its head (previously concerned about spies and secrecy).
In 1986, Howard Bloom combined the concepts of apoptosis, parallel distributed processing, group selection, and the superorganism to produce a theory of how a collective intelligence works [4]. Later, he went further and showed how collective intelligences like those of competing bacterial colonies and of competing human societies can be explained in terms of computer-generated “complex adaptive systems” and the “genetic algorithms”, concepts pioneered by John Holland. [2]
David Skrbina [5] cites the concept of a ‘group mind’ as being derived from Plato’s concept of panpsychism (that mind or consciousness is omnipresent and exists in all matter). He follows the development of the concept of a ‘group mind’ as articulated by Hobbes in relation to his Leviathan which functioned as a coherent entity and Fechner’s arguments for a collective consciousness of mankind. He cites Durkheim as the most notable advocate of a ‘collective consciousness” and Teilhard as the thinker who has developed the philosophical implications of the group mind more than any other.
Collective intelligence is an amplification of the precepts of the Founding Fathers, as represented by Thomas Jefferson in his statement, “A Nation’s best defense is an educated citizenry.” During the industrial era, schools and corporations took a turn toward separating elites from the people they expected to follow them. Both government and private sector organizations glorified bureaucracy and, with bureaucracy, secrecy and compartmentalized knowledge. In the past twenty years, a body of knowledge has emerged which demonstrates that secrecy is actually pathological, and enables selfish decisions against the public interest. Collective intelligence restores the power of the people over their society, and neutralizes the power of vested interests that manipulate information to concentrate wealth.
[edit] Types of collective intelligence
[edit] Examples of collective intelligence
The best-known collective intelligence projects are political parties, which mobilize large numbers of people to form policy, select candidates and to finance and run election campaigns. Military units, trade unions, and corporations are focused on more narrow concerns but would satisfy some definitions of a genuine “C.I.”—the most rigorous definition would require a capacity to respond to very arbitrary conditions without orders or guidance from “law” or “customers” that tightly constrain actions. Another example is in which online advertising companies like BootB are using collective intelligence in order to bypass marketing agencies.
Improvisational actors also experience a type of collective intelligence, which they term ‘Group Mind’.
[edit] Mathematical techniques
One measure sometimes applied, especially by more artificial intelligence focused theorists, is a “collective intelligence quotient” (or “cooperation quotient”)—which presumably can be measured like the “individual” intelligence quotient (IQ)—thus making it possible to determine the marginal extra intelligence added by each new individual participating in the collective, thus using metrics to avoid the hazards of group think and stupidity.
In 2001, Tadeusz (Ted) Szuba from AGH University in Poland proposed a formal model for the phenomenon of Collective Intelligence. It is assumed to be an unconscious, random, parallel, and distributed computational process, run in mathematical logic by the social structure. [6].
In this model, beings and information are modeled as abstract information molecules carrying expressions of mathematical logic. They are quasi-randomly displacing due to their interaction with their environments with their intended displacements. Their interaction in abstract computational space creates multithread inference process which we perceive as Collective Intelligence. Thus, a non-Turing model of computation is used. This theory allows simple formal definition of Collective Intelligence as the property of social structure and seems to be working well for a wide spectrum of beings, from bacterial colonies up to human social structures. Collective Intelligence considered as a specific computational process is providing a straightforward explanation of several social phenomena. For this model of Collective Intelligence, the formal definition of IQS (IQ Social) was proposed and was defined as “the probability function over the time and domain of N-element inferences which are reflecting inference activity of the social structure.” While IQS seems to be computationally hard, modeling of social structure in terms of a computational process as described above gives a chance for approximation. Prospective applications are optimization of companies through the maximization of their IQS, and the analysis of drug resistance against Collective Intelligence of bacterial colonies.[6]
[edit] Opposing views
Skeptics, especially those critical of artificial intelligence and more inclined to believe that risk of bodily harm and bodily action are the basis of all unity between people, are more likely to emphasize the capacity of a group to take action and withstand harm as one fluid mass mobilization, shrugging off harms the way a body shrugs off the loss of a few cells. This strain of thought is most obvious in the anti-globalization movement and characterized by the works of John Zerzan, Carol Moore, and Starhawk, who typically shun academics. These theorists are more likely to refer to ecological and collective wisdom and to the role of consensus process in making ontological distinctions than to any form of “intelligence” as such, which they often argue does not exist, or is mere “cleverness”.
Harsh critics of artificial intelligence on ethical grounds are likely to promote collective wisdom-building methods, such as the new tribalists and the Gaians. Whether these can be said to be collective intelligence systems is an open question. Some, e.g. Bill Joy, simply wish to avoid any form of autonomous artificial intelligence and seem willing to work on rigorous collective intelligence in order to remove any possible niche for AI.
[edit] Recent developments
Growth of the Internet and mobile telecom has also highlighted “swarming” or “rendezvous” technologies that enable meetings or even dates on demand. The full impact of such technology on collective intelligence and political effort has yet to be felt, but the anti-globalization movement relies heavily on e-mail, cell phones, pagers, SMS, and other means of organizing before, during, and after events. One theorist involved in both political and theoretical activity, Tom Atlee, codifies on a disciplined basis the connections between these events and the political imperatives that drive them. The Indymedia organization does this in a more journalistic way, and there is some coverage of such current events even here at Wikipedia.
It seems likely that such resources could combine in future into a form of collective intelligence accountable only to the current participants but with some strong moral or linguistic guidance from generations of contributors – or even take on a more obviously political form, to advance some shared goals.
Systems intelligence
Collective effervescence
Crowd psychology
Collaborative intelligence
Collaborative human interpreter
Collaborative software and Wikis
Distributed cognition
Facilitation and Facilitator
Group behaviour
Human-based computation
Noosphere
Open-space meeting
Preference elicitation
Recommendation system
Smart mob
Bees Algorithm
Group mind (science fiction)
The Wisdom of Crowds
[edit] Notes
^ George Pór, Blog of Collective Intelligence
^ a b Howard Bloom, Global Brain: The Evolution of Mass Mind from the Big Bang to the 21st Century, 2000
^ Émile Durkheim, The Elementary Forms of Religious Life, 1912.
^ Howard Bloom, The Lucifer Principle: A Scientific Expedition Into the Forces of History, 1995
^ Skrbina, D., 2001, Participation, Organization, and Mind: Toward a Participatory Worldview [1], ch. 8, Doctoral Thesis, Centre for Action Research in Professional Practice, School of Management, University of Bath: England
^ a b Szuba T., Computational Collective Intelligence, 420 pages, Wiley NY, 2001
Sun, Ron, (2006). “Cognition and Multi-Agent Interaction”. Cambridge University Press.
The external links in this article may not comply with Wikipedia’s content policies or guidelines.
Please improve this article by removing excessive or inappropriate external links.
MIT Center for Collective Intelligence
MIT Handbook of Collective Intelligence
Blog of Collective Intelligence (George Pór)
The Co-Intelligence Institute
Blog of Evolving Collective Intelligence(Tom Atlee)
Managing Collective Intelligence, Toward a New Corporate Governance
Jatalla’s Collective Intelligence-Based Search Engine
Prediction Markets Cluster – non-commercial, not for-profit industry consortium on collective intelligence
StoryCode — book recommendation system based on the “wisdom of the masses”.
TheTransitioner.org
Cultivating Society’s Civic Intelligence Doug Schuler. Journal of Society, Information and Communication, vol 4 No. 2.
Superorganism. Howard Bloom, An excerpt from The Lucifer Principle: A Scientific Expedition Into the Forces of History
CrowdRules Do-it-yourself Collective Intelligence site
Information, Éthique Rationnelle et Intelligence Collective
Blog on Connected Intelligence
An article on how to implement a recommendations system with ruby on Rails
Retrieved from “http://en.wikipedia.org/wiki/Collective_intelligence“
Categories: All articles with unsourced statements | Articles with unsourced statements since February 2007 | Wikipedia external links cleanup | Collective intelligence | Superorganisms | Futurology | Intelligence by type | Crowd psychology
Posted in Collective Intelligence | Tagged Collective Intelligence | Leave a Comment
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ONCAP Acquires Walter Surface Technologies
ONCAP has purchased a majority stake in Walter Surface Technologies in partnership with the existing management team. The Walter Group will retain a minority interest in the company.
Walter is a provider of innovative solutions for the metal working industry. Its consumable metal working solutions include abrasives, tooling, power tools, chemical solutions and welding process solutions. The company sells its portfolio of products to a diverse array of end markets, including metal fabrication, transportation, construction, energy, mining, forestry and lumber, food and pharmaceuticals. Walter was founded in 1952 by Walter Somers and, over the past 30 years, his son Pierre Somers led the company and expanded it internationally.
"Walter is committed to creating the best performing products and offering innovative, safe, user-friendly and environmentally conscious solutions to its customers," said Gregory Baylin, a Managing Director with ONCAP. "The company's dedication to excellence and strong workforce are what attracted us to the business. We are thrilled to partner with the management team and the founding family to build upon the entrepreneurial spirit and vision Walter and Pierre Somers created."
"ONCAP's Canadian roots and outstanding investment track record make it an ideal partner for us," said Marc-André Aubé, the newly-appointed CEO of Walter. "Together, we will continue to focus on providing the best solutions to our customers to improve their productivity and make their jobs easier and safer. ONCAP's support will help us grow both organically and through strategic add-on acquisitions."
"This transaction is the logical step to take Walter to new and exciting heights. The company is in great hands with Marc-André and the management team we have worked hard to build," said Pierre Somers, the retiring Chairman and CEO of Walter and the Chairman and CEO of Walter Group. "We are excited to remain a minority shareholder and watch the company's growth during this next chapter. The Walter Group will now turn its focus to expanding our investing activities."
info@oncap.com
www.oncap.com
810 Day Hill Road
Windsor, CT 06095
info.us@walter.com
www.walter.com
Optomec Acquires Huffman
Northrop Grumman Expands Arizona Operations
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Molecular and Cellular Pediatrics
Mini review
Mechanism of human rhinovirus infections
Dieter Blaas2 &
Renate Fuchs1
Molecular and Cellular Pediatrics volume 3, Article number: 21 (2016) Cite this article
217 Altmetric
About 150 human rhinovirus serotypes are responsible for more than 50 % of recurrent upper respiratory infections. Despite having similar 3D structures, some bind members of the low-density lipoprotein receptor family, some ICAM-1, and some use CDHR3 for host cell infection. This is also reflected in the pathways exploited for cellular entry. We found that even rhinovirus serotypes binding the same receptor can travel along different endocytic pathways and release their RNA genome into the cytosol at different locations. How this may account for distinct immune responses elicited by various rhinoviruses and the observed symptoms of the common cold is briefly discussed.
Human rhinoviruses (HRVs) account for more than 50 % of upper respiratory tract infections. The disease is known as the common cold that usually resolves within 5–7 days. Symptoms include nasal stuffiness, sneezing, coughing, and a sore throat but about 12–32 % of HRV infections in children of less than 4 years are asymptomatic [1]. Treatment is so far only palliative as no vaccination and approved antivirals are available; because of the usually annoying but uncomplicated course of the disease, only drugs without side effects will be accepted by otherwise healthy patients. However, rhinovirus infections on top of chronic obstructive pulmonary disease (COPD), asthma, or cystic fibrosis (CF) might become life-threatening increasing the demand for the development of such antivirals [2].
Pre-school children can experience an upper respiratory infection up to 8 to 12 times per year (reviewed in [3]) that might lead to wheezing, otitis media, bronchiolitis, exacerbations of asthma, CF, or COPD and aggravate allergic reactions. The newly discovered RV-C species is thought to account for a significant proportion of HRV-related illness, especially in infants [4].
The nasal epithelium
The main site of RV infections is the nasal mucosa. The nasal cavity is lined by a pseudostratified epithelium composed of columnar, ciliated epithelial cells, mucous-secreting goblet cells, and basal cells [5]; lymphocytes, mast cells, dendritic cells, and macrophages migrate to and then home in the epithelium under pathologic conditions. The epithelium is anchored in the underlying extracellular matrix that contains vascular endothelial cells and submucosal glands. The luminal, ciliary surface of the airways is covered by periciliary liquid and a mucus layer trapping inhaled particles such as bacteria and viruses. Mucus produced by the glands and goblet cells contains water, ions (e.g., Na+, Cl−, and K+), glycoproteins, and immunoglobulins such as IgG and polymeric IgA (pIgA) [6]. Beating cilia transport the mucus layer together with adhering particles to the oral cavity where it is swallowed; digestion then leads to destruction of the infectious agent. Mucociliary clearance requires a balance between ciliary beat, volume, and composition of mucus and periciliary fluid. This balance is perturbed in chronic inflammatory lung diseases such as CF and COPD. In CF, mucus composition, viscosity, and pH (a mean of 6.57 versus 7.18 in controls) are altered, rendering the airways more susceptible to infections [7].
HRV receptors, entry, and replication
HRVs are non-enveloped with a ss(+)RNA genome that is protected by an icosahedral protein capsid built of 60 copies each of the four viral proteins VP1–VP4 [1]. Based on phylogeny, more than 150 HRV types are classified as species A, B, and C [8]. Twelve HRV-A (the minor group) bind members of the low-density lipoprotein receptor (LDLR) family whereas the remaining A and B types (the major group) bind intercellular adhesion molecule-1 (ICAM-1) [9, 10]; for HRV-C, the recently identified CDHR3 might serve as a receptor [11]. The mechanisms of entry and uncoating of HRV-C are unknown; we will thus limit the discussion to HRV-A and B.
For infection, the cognate receptor must be accessible to the virus, i.e., at the apical surface of ciliated epithelial cells. While reports on the location of ICAM-1 in the healthy nasal mucosa are contradictory, it is generally agreed that this receptor is upregulated upon inflammation [12]. Re-investigating this issue, we detected ICAM-1 at the ciliated surface of all nasal epithelial cells in the nasal tissue from healthy individuals (Ellinger et al., to be published). As expected from its “normal” physiologic function, LDLR is located at the basolateral plasma membrane of the polarized airway, intestinal, renal, and hepatic cell lines. We were thus surprised to find that LDLR and LDLR-related protein 1 (LRP-1) are present at the apical side of the nasal epithelial cells and thus available for uptake of virus at its main port of entry (Ellinger et al., to be published).
HRVs of species A and B investigated so far enter cells by receptor-mediated endocytosis [13]. In the endosomal lumen, they convert into subviral A (altered) particles devoid of the innermost capsid protein VP4 but still containing the RNA genome. After the release of the RNA (uncoating) into the cytoplasm, empty capsids remain (Fig. 1). Minor group HRVs exclusively depend on the low endosomal pH for this conformational modification and uncoating occurs even at 20 °C [13, 14]. Although uncoating of HRV-A2 is receptor-independent, the ß-propeller of LDLR and LRP plays a role in releasing the virus in early endosomes thus enabling its transport to late endosomes (pH ≤ 5.6), a station most suitable for RNA transfer into the cytosol [13]. On the other hand, it is generally accepted that conversion of ICAM-1 binding HRVs into A particles is facilitated by the receptor above 26 °C [15]; in addition, depending on the serotype, the process also requires low endosomal pH [16]. However, major group HRV-A89 can also convert at 20 °C in a low pH-dependent but presumably receptor-independent manner and, even more importantly, it follows a route different from the one taken by HRV-B14 (Conzemius et al., manuscript submitted). While HRV-A89 productively uncoats in the perinuclear recycling compartment, HRV-B14 penetrates into the cytoplasm by rupturing endosomes en route to the lysosomes in a temperature- (≥20 °C), low-pH, and ICAM-1-dependent manner (Fig. 1). Whether this is related to different affinity of ICAM-1 for the respective virus—and associated differences in dissociation of the virus-receptor complex—is currently under investigation.
HRV entry and uncoating in ciliated nasal epithelial cells. Left, HRV-A2; middle, HRV-A89; and right, HRV-B14. For clarity, minor group and major group receptors (LDLR and ICAM-1, respectively) are depicted separately although they are co-expressed at the ciliated (apical) side of nasal epithelial cells as well as on the entire plasma membrane of basal cells. After binding to the respective receptor at the ciliated surface, the viruses are internalized and delivered into early endosomes. For HRV-A2, the mildly acidic pH in these compartments leads to dissociation of the virus from its receptor. While LDLR is returned to the apical plasma membrane via perinuclear recycling endosomes, the virus is directed to late endosomes. The low pH ≤ 5.6 in late endosomes converts native viruses into subviral A particles. Subsequently, the viral RNA is released and the remaining empty capsids (subviral B particles) are shuttled to and degraded in lysosomes. In contrast, HRV-A89 together with ICAM-1 is sorted into the recycling pathway. Perinuclear recycling endosomes are similarly acidic as late endosomes resulting in conversion of native HRV-A89 into A and then into B particles. After the transfer of the viral RNA into the cytoplasm, empty capsids are most likely returned to the apical mucous layer. After binding to the same receptor, HRV-B14 is routed from early endosomes into the pathway to lysosomes. However, after undergoing the ICAM-1-dependent conformational modification, the virus ruptures the endosomal membrane leading to RNA uncoating and its penetration into the cytoplasm. Thus, the viral capsid as well as the viral RNA escapes lysosomal degradation. So far, the fate of ICAM-1 is unknown
Once the RNA has arrived in the cytoplasm, it is translated into a polyprotein. After autocatalytic cleavage into the structural (capsid) and non-structural proteins, the RNA is replicated by the viral polymerase. Finally, infectious progeny is assembled and released into the nasal cavity [1]. In contrast to HRV infection in tissue culture cells, airway epithelial cells of patients are not lysed for virus release; as shown for other enteroviruses, it is thus possible that cell-to-cell spread might occur via virus-carrying microvesicles [17].
Host response to HRV infections
Although initially believed that HRV infection was limited to the upper airways, replicating virus was found in ciliated epithelial cells of the lower respiratory tract. Infected cells appear in patches, and only 10 % of the ciliated cells produce viral proteins and RNA [18]. Similar results had been obtained with in situ hybridization in nasal biopsies, again indicating that only a small proportion of cells were infected [19]. Nevertheless, basal cells are more susceptible to infection as compared to fully differentiated ciliated cells [20]. This might be related to the higher expression level of ICAM-1 in basal cells versus ciliated cells (Fuchs, unpublished observations). The absence of visible cytopathic alterations in the airway epithelium led to the hypothesis that the symptoms are rather due to the immune response of the host [21]. Upon HRV entry into and replication in ciliated epithelial cells, signalling pathways are activated leading to the release of various cytokines (IL-1ß, TNF, IL-8, IL-6, IL-11), chemokines (Rantes, MCP-1, MP-10), vasoactive peptides (bradykinin), and growth factors (VFGF) [21]. Consequently, inflammatory cells (leukocytes, granulocytes, monocytes) become activated and invade the submucosa. This results in amplification of the inflammatory process and the typical symptoms of the common cold. Conversely, HRV infections are controlled by innate and adaptive immune responses. Type-I interferons are the early mediators of the innate immune system, while neutralizing IgA and IgG in serum and secretions are observed 1–2 weeks after infection as a consequence of the adaptive immune response. Nasal epithelial cells express the pIgA receptor (pIgR) and the neonatal Fc-receptor (FcRn) that transport the respective immunoglobulins into nasal secretions [22]. Expression of FcRn in the ciliated epithelial cells and in dendritic cells (DC) in the nasal mucosa might contribute to mucosal immunity as shown for FcRn in the intestine [23].
How could the entry pathway taken by a given rhinovirus impact on the immune response? We presented evidence for HRV-A2 transferring its genome into the cytosol via a pore in the membrane and the remaining empty capsid being directed towards lysosomes where it is degraded. On the other hand, HRV-B14 breaks the endosomal membrane resulting in arrival of viral proteins in the cytoplasm [13]. As a consequence, one might hypothesize that the proteins of incoming virus are presented to the immune system either as products of proteasomal (HRV-B14) or lysosomal (HRV-A2) processing. Degradation products of the former would thus be mainly presented by the MHC-I system and the latter mainly by the MHC-II system. Furthermore, pattern recognition receptors in the endosome are different from those in the cytosol [1]. Such differences might impact on differences in the primary immune response; nevertheless, in the absence of further experimentation, this remains pure speculation.
HRVs are a major cause of respiratory infections of infants. The numerous serotypes are precluding the development of a vaccine, and current treatments only palliate the symptoms. HRVs enter from the apical side of the cells lining the airways by receptor-mediated endocytosis via LDLR and ICAM-1. We demonstrated that all nasal epithelial cells express ICAM-1 and LDLR at their ciliated side and that two ICAM-1 binding HRV types exhibit different temperature dependence of uncoating and take distinct routes inside the cell for genome release (Fig. 1). This may explain why different HRVs elicit different signals during cell entry resulting in different host responses to infection [24, 25]. Understanding the details of receptor binding, entry, and uncoating is crucial for identifying novel means of fighting the common cold.
Jacobs SE, Lamson DM, St George K, Walsh TJ (2013) Human rhinoviruses. Clin Microbiol Rev 26:135–162
Thibaut HJ, Lacroix C, De Palma AM, Franco D, Decramer M, Neyts J (2016) Toward antiviral therapy/prophylaxis for rhinovirus-induced exacerbations of chronic obstructive pulmonary disease: challenges, opportunities, and strategies. Rev Med Virol 26:21–33
Turner RB (1997) Epidemiology, pathogenesis, and treatment of the common cold. Ann Allergy Asthma Immunol 78:531–539
Miller EK (2010) New human rhinovirus species and their significance in asthma exacerbation and airway remodeling. Immunol Allergy Clin North Am 30:541–552
Knight DA, Holgate ST (2003) The airway epithelium: structural and functional properties in health and disease. Respirology 8:432–446
Yoshida M, Kobayashi K, Kuo TT, Bry L, Glickman JN, Claypool SM, Kaser A, Nagaishi T, Higgins DE, Mizoguchi E, Wakatsuki Y, Roopenian DC, Mizoguchi A, Lencer WI, Blumberg RS (2006) Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria. J Clin Invest 116:2142–2151
Song Y, Salinas D, Nielson DW, Verkman AS (2006) Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis. Am J Physiol Cell Physiol 290:C741–C749
Palmenberg AC, Spiro D, Kuzmickas R, Wang S, Djikeng A, Rathe JA, Fraser-Liggett CM, Liggett SB (2009) Sequencing and analyses of all known human rhinovirus genomes reveal structure and evolution. Science 324:55–59
Staunton DE, Merluzzi VJ, Rothlein R, Barton R, Marlin SD, Springer TA (1989) A cell adhesion molecule, ICAM-1, is the major surface receptor for rhinoviruses. Cell 56:849–853
Hofer F, Gruenberger M, Kowalski H, Machat H, Huettinger M, Kuechler E, Blaas D (1994) Members of the low densitylipoprotein receptor family mediate cell entry of a minor-group common cold virus. Proc Nat Acad Sci USA 91:1839–1842
Bochkov YA, Watters K, Ashraf S, Griggs TF, Devries MK, Jackson DJ, Palmenberg AC, Gern JE (2015) Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication. Proc Natl Acad Sci U S A 112:5485–5490
Winther B, Arruda E, Witek TJ, Marlin SD, Tsianco MM, Innes DJ, Hayden FG (2002) Expression of ICAM-1 in nasal epithelium and levels of soluble ICAM-1 in nasal lavage fluid during human experimental rhinovirus infection. Arch Otolaryngol Head Neck Surg 128:131–136
Fuchs R, Blaas D (2010) Uncoating of human rhinoviruses. Rev Med Virol 210:281–297
Jurgeit A, Moese S, Roulin P, Dorsch A, Lotzerich M, Lee WM, Greber UF (2010) An RNA replication-center assay for high content image-based quantifications of human rhinovirus and coxsackievirus infections. Virol J 7:264
Casasnovas JM, Springer TA (1994) Pathway of rhinovirus disruption by soluble intercellular adhesion molecule 1 (ICAM-1): an intermediate in which ICAM-1 is bound and RNA is released. J Virol 68:5882–5889
Nurani G, Lindqvist B, Casasnovas JM (2003) Receptor priming of major group human rhinoviruses for uncoating and entry at mild low-pH environments. J Virol 77:11985–11991
Inal JM, Jorfi S (2013) Coxsackievirus B transmission and possible new roles for extracellular vesicles. Biochem Soc Trans 41:299–302
Mosser AG, Brockman-Schneider R, Amineva S, Burchell L, Sedgwick JB, Busse WW, Gern JE (2002) Similar frequency of rhinovirus-infectible cells in upper and lower airway epithelium. J Infect Dis 185:734–743
Arruda E, Boyle TR, Winther B, Pevear DC, Gwaltney JM Jr, Hayden FG (1995) Localization of human rhinovirus replication in the upper respiratory tract by in situ hybridization. J Infect Dis 171:1329–1333
Jakiela B, Brockman-Schneider R, Amineva S, Lee WM, Gern JE (2008) Basal cells of differentiated bronchial epithelium are more susceptible to rhinovirus infection. Am J Respir Cell Mol Biol 38:517–523
Kennedy JL, Turner RB, Braciale T, Heymann PW, Borish L (2012) Pathogenesis of rhinovirus infection. Curr Opin Virol 2:287–293
Heidl S, Ellinger I, Niederberger V, Waltl EE, Fuchs R (2015) Localization of the human neonatal Fc receptor (FcRn) in human nasal epithelium. Protoplasma. doi:10.1007/s00709-015-0918-y
Rath T, Baker K, Pyzik M, Blumberg RS (2014) Regulation of immune responses by the neonatal fc receptor and its therapeutic implications. Front Immunol 5:664
Wark PA, Grissell T, Davies B, See H, Gibson PG (2009) Diversity in the bronchial epithelial cell response to infection with different rhinovirus strains. Respirology 14:180–186
Schuler BA, Schreiber MT, Li L, Mokry M, Kingdon ML, Raugi DN, Smith C, Hameister C, Racaniello VR, Hall DJ (2014) Major and minor group rhinoviruses elicit differential signaling and cytokine responses as a function of receptor-mediated signal transduction. PLoS One 9:e93897
This study is funded by the Austrian Science Fund P-274444-B13.
Department of Pathophysiology and Allergy Research, Medical University of Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria
Renate Fuchs
Department of Medical Biochemistry, Max F. Perutz Laboratories, Vienna Biocenter, Medical University of Vienna, Vienna, Austria
Dieter Blaas
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Correspondence to Renate Fuchs.
Blaas, D., Fuchs, R. Mechanism of human rhinovirus infections. Mol Cell Pediatr 3, 21 (2016) doi:10.1186/s40348-016-0049-3
Nasal epithelium
Human rhinoviruses
Rhinovirus receptors
Recent advances in pediatric lung diseases
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Famous put-downs #3
After my previous posts – Famous put-downs #1 and Famous put-downs #2, as well as Scorn and More Scorn – here is another selection of put-downs:
There’s one area where Donald’s experience could be invaluable, and that’s closing Guantánamo. Because Trump knows a thing or two about running waterfront properties into the ground. Barack Obama
James Franco: acting, teaching, directing, writing, producing, photography, soundtracks, editing; is there anything you can do? Actress and comedian Natasha Leggero on The Disaster Artist star.
So boring, you fall asleep halfway through her name Alan Bennett on Arianna Stassinopoulos
Hey buddy you ought to save your breath. You’ll need it later to blow up your inflatable date. Comedian Rodney Dangerfield to heckler
David Beckham sent the people of Scotland an open letter. An open letter – because he couldn’t work out how to get it into envelope.” Comedian Frankie Boyle during the Scottish independence referendum
The 4th Earl of Sandwich: ‘Sir, I do not know whether you will die on the gallows or of the pox’
John Wilkes: ‘That depends, my lord, on whether I embrace your lordship’s principles or your mistress’
If Kim wants us to see a part of her we’ve never seen, she’s gonna have to swallow the camera. Bette Midler
Why don’t you go into that corner and finish evolving? Comedian Russell Kane to heckler
The worst person at controlling a party since Michael Barrymore. Frankie Boyle on Theresa May
Madam, you have between your legs an instrument capable of giving pleasure to thousands and all you can do is scratch it Sir Thomas Beecham to a cellist
Look, it’s all right to donate your brain to science but shouldn’t you have waited till you died? Comedian Arthur Smith to heckler
If ignorance ever goes to $40 a barrel, I want drilling rights on George Bush’s head. Commentator Jim Hightower on George HW Bush
I’m sorry, I don’t speak Orc. Comedian Brendan Dodds to heckler
People say that Steve Jobs died too soon. But I think it was a fitting metaphor for his company’s attitude to battery life. Comedian Frankie Boyle
Leave a Comment » | Quotes | Permalink
30 Language bar jokes
I am sucker for language nerd jokes. See my previous post, Language humour. I saw a collection of language bar jokes in the staffroom. I thought I would feature them, as well as some others I found online. Here is my selection:
A run-on sentence walks into a bar it starts flirting. With a cute little sentence fragment.
A comma splice walks into a bar, it has a drink and then leaves.
A dangling participle walks into a bar. After finishing a drink, the bartender asks it to leave.
A misplaced modifier walks into a bar owned by a man with a glass eye named Ralph.
Two possessive apostrophes walk into the bar as if they owned the place.
An antecedent walked into a bar, and they ordered a drink.
A non sequitur walks into a bar. In a strong wind, even turkeys can fly.
A synonym strolls into a tavern.
An allusion walks into a bar, despite the fact that alcohol is its Achilles’ heel.
Bartender asks a woman what she wants. “An entendre,” she says. “Make it a double.” So he gives it to her.
A subject and a verb have a disagreement in a bar, and one of them pull out a pistol.
A malapropism walks into a bar, looking for all intensive purposes like a wolf in cheap clothing, muttering epitaphs and casting dispersions on his magnificent other, who takes him for granite.
An alliteration traipsed into a tavern, where it tangled tempestuously with an insistent, illiterate intern.
A mixed metaphor walks into a bar, seeing the handwriting on the wall but hoping to nip it in the bud.
A pun, a play on words, and a limerick walk into a bar. No joke.
At the end of the day, a cliché walks into a bar — fresh as a daisy, cute as a button, and sharp as a tack.
Hyperbole totally rips into this insane bar and absolutely destroys everything.
An interjection walked in to a bar. OUCH!
A heedless homonym walks into a bar. You think he wood of scene it write in front of him.
A hyphenated word and a non-hyphenated word walk into a bar and the bartender nearly chokes on the irony.
A typo wakled into a bar.
A dyslexic walks into a bra.
An Oxford comma walks into a bar. Orders a gin, and tonic.
A gerund and an infinitive walk into a bar, drinking to forget.
A simile walks into a bar, as parched as a desert.
Papyrus and Comic Sans walk into a war. The bartender says, “Get out — we don’t serve your type.”
An oxymoron walked into a bar, and the silence was deafening.
Three intransitive verbs walk into a bar. They sit. They converse. They depart.
A verb walks into a bar, sees a beautiful noun, and suggests they conjugate. The noun declines.
A figure of speech literally walks into a bar and ends up getting figuratively hammered.
2 Comments | Learning | Permalink
Ten years in the blogosphere
It’s typical of me to forget an anniversary – just ask my long-suffering wife. On April 4th 2008 I did my first post, In Praise of Wikipedia. Now 940 posts later I’m still standing. I really had no idea that it would last a decade. I had planned to commemorate it, but it just slipped my mind.
The 8th year of the 3rd millennium began on a Tuesday. It was the International Year of Languages, Planet Earth, Sanitation and the Potato. The GFC was still in its infancy. George W. Bush was still president and would be succeeded by Barrack Obama, who defeated John McCain in November. It was a year of bailouts, especially after the collapse of Lehman Brothers. The financial may have been bad more long-term damage was done by The Sex and the City film. It was the year that Spain would win their first European Championship on colour TV.
It’s been good fun. The most difficult thing has been finding the time. I remember when I started I used to do four posts a week. Now I tend to do one or two a week. Nevertheless, I still love doing it and I hope to continue to share my view of the world.
1 Comment | Articles | Permalink
Witty book titles
Don’t judge a book by its cover – judge it by its title instead. There are some really clever book titles out there. They often involve puns or allusions to other books. Here are some of my favourites:
The Origins of the Specious, Patricia T. O’Conner 33 Revolutions Per Minute, Dorian Lynskey Here’s Looking at Euclid, Alex Bellos Moby-Duck, Donovan Hohn Young Winstone, Ray Winstone The Missionary Position, Christopher Hitchens A Very British Coop: Pigeon Racing From Blackpool To Sun City, Mark Collings Kill Two Birds & Get Stoned, Kinky Friedman Gone with the Windsors, Laurie Graham Pies and Prejudice: In Search of the North, Stuart Maconie Sleeping Dogs Don’t Lay: Practical Advice For The Grammatically Challenged, Richard Lederer
Leave a Comment » | Books & Reading, Language | Permalink
The dark arts of the restaurant critic
We are all critics now. Thanks to the smartphones we carry around in our pockets and websites such as Yelp, Instagram and food blogs, restaurant reviews have become crowd-sourced. For example, statistics show 2015 Bottega Louie had 10,398 reviews and over 13,000 photos on Yelp. This popular involvement may be considered more democratic. Now we the citizens can decide whether a restaurant is good or not. It is not enough to satisfy the sophisticated palate of the professional food critic, who they may well recognise and who will only visit once. But with the citizen reviewers they will have to be consistently on their toes.
What does this mean for the professional critic? One I heard complaining that they enjoyed influence, but not power. Restaurant critics have been around longer than you may think. In a previous post I looked at the rise of the Michelin Guide, which was first produced in 1900. Food guides go back even further, to the beginning of the 19th century. Then we have newspapers. The second half of that century was a golden age for them. Anjd they started to write about restaurants. It is difficult to know when the first ever restaurant review was. One early example appears to be the anonymous How We Dine column that ran for the first time in The New York Times on 1 January 1859. The critics remit was to “Dine somewhere else today and somewhere else tomorrow. I wish you to dine everywhere. From the Astor House Restaurant to the smallest description of dining salon in the city, in order that you may furnish an account of all these places. The cashier will pay your expenses”
One of the places they would visit was the prestigious Delmonico’s, which I first heard about in Caleb Carr’s The Alienist. The critic provides a glowing review of the establishment:
“No nobleman of England — no Marquis of the ancienne nobless — was ever better served or waited on in greater style that you will be in a private room at Delmonico’s. The lights will be brilliant, the waiters will be curled and perfumed and gloved, the dishes will be strictly en règle and the wines will come with precision of clock-work that has been duly wound up. If you “pay your money like a gentleman,” you will be fed like a gentleman, and no mistake… The cookery, however, will be superb, and the attendance will be good. If you make the ordinary mistakes of a untraveled man, and call for dishes in unusual progression, the waiter will perhaps sneer almost imperceptibly, but he will go no further, if you don’t try his feelings too harshly, or put your knife into your mouth.”
However, what we all really enjoy is the schadenfreude of a scathing review. A master of this was the late AA Gill. He once described pre-Kitchen Nightmares Gordon Ramsay as “a failed sportsman who acts like an 11-year-old”, which led to his being kicked out of Ramsay’s Aubergine restaurant. Another recipient of his barbs said that the critic owed him £500,000 for closing down his restaurant:
“You closed down my restaurant. Your review was malicious, you did it through spite, for the sake of a funny line and because it’s easier to write horrid things.” Gill didn’t hold back in his reply:
“Do you know the reason your restaurant failed is that it was an unbelievably shitty restaurant, the food was disgusting!’
In Tour De Gall his takedown of L’Ami Louis in Paris is work of art itself:
Twenty minutes later, possibly under their own steam, the snails arrive. Vesuvian, they bubble and smoke in a magma of astringent garlic butter and parsley. We grasp them with the spring-loaded specula and gingerly unwind the dark gastropods, curling like dinosaur boogers. They go on and on, expanding onto the plate as if they were alien. We have to cut them in half, which is just wrong. The rule with snails is: Don’t eat one you couldn’t get up your nose.”
“What you actually find when you arrive at L’Ami Louis is singularly unprepossessing. It’s a long, dark corridor with luggage racks stretching the length of the room. It gives you the feeling of being in a second-class railway carriage in the Balkans. It’s painted a shiny, distressed dung brown. The cramped tables are set with labially pink cloths, which give it a colonic appeal and the awkward sense that you might be a suppository. In the middle of the room is a stubby stove that also looks vaguely proctological..”
Here are a few more of my favourite negative reviews:
Gino D’Acampo: My Restaurant at London’s Euston station
The risotto with scallops is where hope goes to die. Jay Rayner
Le Cinq, Paris
If I work hard, with luck, one day I may be able to forget. Jay Rayner
Leon De Bruxelles, London
The meat inside the shells is small and shrivelled and dry; each shell contains what looks like the retracted scrotum of a hairless cat. Jay Rayner
Razes Le Relais, Paris
For the “secret sauce”, a mustard-based crime against humanity (of course they keep it secret—if they published the recipe, Hans Blix would be out of retirement in five minutes), …” Matthew Norman
Roy‘s, New York
If clowns had a cuisine, this would be it. The food at Roy’s is foolish, a parade of exotic ingredients, confused and overpowering sauces, and ideas piled one on top of the other until the recipes simply collapse under their own weight. Almost every dish is sweet — so sweet that the desserts seem like palate cleansers. William Grimes
Kobe Club, New York
If Akira Kurosawa hired the Marquis de Sade as an interior decorator, he might end up with a gloomy rec room like this. Will the last samurai to leave please turn on the lights? Frank Bruni
Guy’s American Kitchen & Bar, New York
Hey, did you try that blue drink, the one that glows like nuclear waste? The watermelon margarita? Any idea why it tastes like some combination of radiator fluid and formaldehyde? Pete Wells
Why are such reviews so enjoyable? “The vocabulary of the bad is just that much more entertaining. When it comes to restaurant reviews, the saying – if you can’t say something nice about someone, don’t say anything at all – doesn’t seem to apply to restaurant reviews.
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KEN GRANT: Ooh La La
byKen_Dyks
Ken discusses the Faces and the crimes of Ron Wood, Facebook and other tech earnings, and the upcoming earnings and data
Poor young grandson, there’s nothing I can say,
You’ll have to learn just like me, and that’s the hardest way,
Full disclosure: I’ve written about Ooh La La before. It was back in the days of “The Left Tail Report” – a publication I put out every quarter, the content of which was so “out there that”, by comparison, my current weekly musings look more like the Editor’s Note in Readers Digest.
Anyone out there remember “The Left Tail Report”?
For those that do, I freely acknowledge that I once dedicated an entire installment to O-L-L. The song – title track from the Faces' last album –is an interchange between a grandfather and grandson about the mysterious ways of women. It was written and sung by Ronnie (Woody) Wood, and I think he did a fine job. By the time of its release, his bandmate Rod the Mod was flaking off to a solo career, whence we began to bear witness to his steady, horrifying, 45-year decline into a caricature of what he once was. From a commercial perspective, the Faces couldn’t survive his departure. Woody soon bailed, of course, to the Stones, and even here I was disappointed. I think they could’ve done better. When Mick Taylor split suddenly, I took great interest in his replacement, hoping for someone like Jeff Beck or even Mick Ronson. But they hired Keith-clone Woody, and I knew then and there they were going to settle into a comfortable middle age. And history proved me right; post Woody’s arrival, they seldom, if ever, challenged themselves musically. For the most part, they have simply mailed it in, writing boring songs, basking in their monumental, unshakeable legacy, and, of course, banking scads of cash along the way.
So Woody’s mid-70’s move arguably ruined two great bands. And it is the demise of the Faces that I particularly lament. So spontaneous, so delightfully under-rehearsed. For years, I’ve offered the following warning to my clients: the only development that could impel a hiatus from my professional toils would be a reunion of the Faces, because I’d have no choice other than to accompany the band on the road. This warning, for the record, still applies.
So it is with all of this in mind that I address the unavoidable the astonishing facial that those modern-day Faces: social media behemoth Facebook, delivered to their investors. Admittedly, nobody can shut up about this, but there’s something strange going on here, and duty calls me to weigh in. Let’s just say that the episode was so catastrophic that it’s causing me to rethink my general approach to financial advisory. Loyal readers will recall that earlier this year, and in advance of Zuck’s much-anticipated testimony on Capitol Hill, I advised him to eschew his trademark tee in favor of his Bar Mitzvah suit. I think he tried to comply, but presumably finding it a poor fit, he at least rocked a reasonable facsimile thereof. And he managed to endure the episode without emerging much worse for the wear. I further predicted that the markets would soon forget the incident, and I was proved right on that score – at least insofar as FB not only recovered, from a valuation perspective, everything it had lost from the grilling, but added another >20% to its historical highs – all within what amounted to about three months. I don’t know if the Zuck Suit did all of the heavy lifting in this respect; let’s just agree it didn’t hurt.
But perhaps thus feeling himself able to fully accept my counsel, he might’ve taken too literally my sentiments that the Q2 earnings cycle was logically setting up for downward guidance. Because boy did he guide down. And he had help. In fact, the earnings call evolved in such a way as hasn’t been seen in these realms, well, in forever. It all began innocently enough. Zuck took to the podium with chipper demeanor. It was a good quarter, he said. Just a tad light on revenues, but gosh almighty aren’t people loving Insty and Snapchat? He then turned the mic over to the redoubtable Sheryl, who put a damper on the festivities by fretting about such matters as currency impacts and ad revenues.
Here, the stock started to waver, but still, we were not in red flag configuration. That is, until 5:20 PM – EDT, when Sheryl punted to CFO Dave (Dr. Doom) Wehner, who not only punctured the sagging balloon, but burned down the all of the party favors, the house and the entire block. He didn’t simply guide down for Q3, or even just for the back half of 2018. He suggested that growth rates would be on a downward trajectory for years. We all know what happened after that.
FB shares plummeted to generate the biggest one day/single stock valuation destruction in market history. Again, a great deal has been written about this, but for our purposes, a number of factors merit our further attention. First, I don’t ever recall a company in such fine shape overall guiding down anywhere near that far into the future. Second, while I am not as laser-focused on earnings as some of my readers, it is my experience that when a CEO brings bad news to the podium, he or she usually drops it in the first five minutes of a call. But the Faces waited nearly an hour and a half before cluing in the investment community their fears that their fabulous innings in the sun are winding down.
I’m puzzled, here, about a number of things. Most of all, there’s no reason on this earth that a company generating > $10B annually in free cash flow, which has 2.5 Billion users (competing, at these levels, with Air and Water as the most ubiquitous product on the planet), and which clearly has resources and reach to continue to achieve astonishing consumer technology breakthroughs, should be talking about topping out on its growth. And for me, there is only one possible explanation: management tanked the stock, wanted it to go down. And hard. The obvious question follows: why?
But whatever the true explanation, I feel it behooves me to now be much more careful in offering my counsel about such matters as earnings guidance, because, if my sentiments are over-interpreted, the consequences can apparently be dire.
There were other hits (Googlers, Amazonians) and misses (beyond FB: Twitterers and Netflixers) across the rest of the week’s earnings extravaganza, but on the whole, we’re still looking at a >20% quarter. We’re now past half-time in this here contest, and I think we can safely assume that the last three months will be shown to have been kind to the bottom lines of public companies. Investors appear, on balance, to be mildly impressed, but pockets of doubt clearly remain, and maybe rightfully so.
The week’s other quarterly tidings feature our first glimpse at Q2 GDP, which clocked in at a robust 4.1%. The media-politic stuck to the script, with the current holders of power not slow to grab all of the credit, while their detractors groped about to tell the other side of the story. By any standard, 4.1 is a pretty solid number, but now, less than 48 hours after its revelation, it already feels like old news. In addition, after months of trade war brinkmanship, there appears to be some sort of détente in place between America and Europe, and this, my loves, if authentic, is unilaterally good news. Among other matters, it caused Commodities to move modestly off the schneid:
But the news isn’t all rosy. Virtually every metric associated with the domestic housing market is on it (the Schneid, that is). And the timing for its underperformance is arguably less than ideal. Bear in mind that ALL macro statistics are backward looking, but Housing particularly so. Right now, we’re getting our first insight into May numbers – a point in the calendar that represents the peak of the selling season. Not much buying (and hence selling) activity is in evidence.
One can identify numerous causes here. Mortgage rates are higher; inventory is low. Some areas in this country are just plain unaffordable.
However, in perhaps the unkindest cut of all, the ubiquitous website www.mansionglobal.com reports that the purchase of American terra firma by non-Americans has suffered a 20% drop. Leading the way are the two biggest sources of historic demand: the Chinese and the Canadians. At the risk of stating the obvious, it’s just possible that their feelings are hurt.
So I’d check any instincts I might otherwise have to ascend to giddiness about the GDP report. Among other matters, as we remain in a turbo-charged information release cycle, it might behoove the rational to be a bit reactive here. Next week brings a number of noteworthy earnings reports. First, of course, there’s Apple, and if that’s not 2018 enough for you, Tesla reports, in characteristic fashion, after the bell on Friday. Also, while admittedly a stretch for some of you, I personally have my eyes on the Pride of Peoria, IL: the Caterpillar Corporation. CAT’s been guiding up but getting no love for their troubles. If the numbers are bad/or and they guide down for the future, it’ll be look out below. I also think their briefing will be greatly informative for such topics as the strength of the overall economy and the potential impacts of trade wars.
Lest we forget, there’s plenty of data love for left out non-equity types as well. Tuesday/Wednesday is the next FOMC meeting, where no action is expected, but for which the accompanying policy statement will be parsed down to the letter. Also meeting – under high-drama conditions – are the Banks of England and Japan, respectively. There’s a good deal riding on these transoceanic monetary policy statement exercises – particularly in Japan, which is showing signs of getting tired of issuing debt at 0% interest rates:
And once we’re through all of that, we can point our peepers to the July Jobs Report, scheduled for release at its regular time next Friday. Everyone expects the number to be a pretty strong one: ~200K in new gigs; maybe a drop in the base rate and a rise in the Labor Force Participation level.
However, in familiar refrain, it is likely that all eyes will be trained towards the Average Hourly Earnings print; perhaps (but not likely) to solve the vexing mystery of why an economy humping along as ours is, that is known to have a labor shortage, cannot seem to gin up the wage inflation that would bring tears of joy across the great wide way.
I’ll be watching closely all week – unless, of course, the Faces reunite and decide to go on tour, at which point matters will be out of my hands. I’m not expecting this, so I wouldn’t worry overmuch on that score. In fact, it may never happen. Rod is working the Casino circuit, no doubt enjoying the swoons of females from ages 8 to 80. I’ll give him a pass on that one. Woody is scheduled to play to crowds in excess of > 100,000 across the globe for the next several months, so he’s presumably unavailable. Ronnie Laine and Ian McLagan have shed their mortal coils, leaving only drummer Kenney Jones to carry on. If so, then the Faces become the Face, and I’m less interested.
The band, no doubt, passes into finite history, but a few of us fans remember, and will try to pay it forward. I did manage to make my son and his friends hip to the Faces, and perhaps one or two of them are carrying on.
Now’s not the right time, but when it comes, I’ll share these gifts with my grandsons. But I won’t overdo this. I’ll play the records, tell the story and leave it at that. From there, we know what to expect: they’ll have to learn just like me, and that’s the hardest way. And now we can conclude this week’s business, as there’s only one more thing to say, and I hope you’ll say (or sing it) with me:
Aspen Trading Group: Are Emerging Markets finally ready to 'emerge'?
EditorKen_Dyks
JOHN MASON: New Thinking About Fiscal Stimulus Policies Is Needed
EditorPaul Krake
AMELIA BOURDEAU: A Look at ECB and Euro - Favoring EUR Crosses
EditorChrisCristi
KEN GRANT: Morning Corn
JOHN MASON: The multilateral trading system and those forgotten
KEN GRANT: All That You Dream (May 20)
JOHN MASON: Contrasting Federal Reserve and ECB policy
AMELIA BOURDEAU: Preparing for stock market déjà vu
JOHN MASON: The New Financial Economy: What Is In Store?
KEN GRANT - Zen and the Art of Capital Preservation
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Subject: Money Morning Mailbag: Will Elections and a Resignation Open the Door for U.S. Budget Changes?
URL: http://mney.co/1GJrf8I
9 + = 18 Required Please enter the correct value.
Peter Orszag
Money Morning Mailbag: Will Elections and a Resignation Open the Door for U.S. Budget Changes?
By Kerri Shannon, Associate Editor, Money Morning - June 25, 2010
Administration officials announced this week that the White House Budget Director Peter Orszag plans to leave U.S. President Barack Obama's Cabinet before work on the next U.S. budget begins, which could be some time in the next few weeks. Orszag would be the first member of President Obama's Cabinet to exit.
The U.S. budget is under scrutiny as the budget deficit is forecast to hit $1.6 trillion by 2011. A President-appointed panel is currently working on budget reduction plans to be presented in a report due in December.
Orszag's strategies as former head of the Congressional Budget Office (CBO) supported a stop to deficit spending, but once he was placed in the budget driver's seat, making significant cuts was nearly impossible with recovery progress slow and unemployment high. Orszag instead ended up helping outline the $787 billion stimulus package in 2009.
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Patients we've helped
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An Important Update on Headley Court
The Ministry of Defence has recently moved the Defence Military Rehabilitation Centre (DMRC) Headley Court (the site of the Royal British Legion MediCinema) to a new site at Stanford Hall, Loughborough. As a result, the MediCinema is currently closed.
Since the Royal British Legion MediCinema opened by Simon Pegg and Nick Frost in 2012, we have given 18,937 cinema experiences to servicemen and women who have experienced life-changing injuries and their families. Over the years, MediCinema has played a key role in their rehabilitation and care, and we are proud to have brought the magic and escapism of the cinema to those who have served our country, like Kgn. Anthony Cooper. He told us about the difference MediCinema made to him:
‘When you are around the same people all the time in a compact environment, it can become disheartening. I am a person who likes to get out there and talk to people. If I can’t get out I become frustrated. I have been here so long (4 years) at DMRC Headley Court people jest in calling me a Veteran.'
‘The cinema has become my main release. Anyone can come to the cinema; therefore I get to meet new groups of people. It’s good to know that there are other people with similar injuries, and have the opportunity to share thoughts with them.
‘At Headley Court we work extremely hard each day, and we are pushed to our limits. I am often very much need of a chill out after a full days rehab. The cinema itself is excellent, lots of space and you can choose who you sit with. You can pull yourself on railings if you’re tired of pulling the wheelchair up ramps, and the floor is clean so you can easily climb from your wheelchair into a comfy seat. I could not do this in a normal cinema and I don’t like it when people look.
‘If it were not for the MediCinema, my little group (Neuro ward) would feel even smaller. The cinema links me in, and it helps me find a positive common space with other patients.’
Here are a few photographic highlights from the last six years:
We’re truly grateful to the Royal British Legion for generously supporting the MediCinema at Headley Court everyone at the DMRC for all their hard work over the years. It is only thanks to you that the MediCinema has enabled so many patients to feel better with film. We hope to open a MediCinema in the new Defence National Military Centre once the clinical facility is fully settled and an appropriate site for the MediCinema has been agreed.
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Exuberance, sincerity, melodrama, banjos—everything that led to Mumford & Sons' rise to superstardom is here on their 2009 debut. Animated by rich harmonies, lightning-fast picking and epic crescendos, tracks like "Little Lion Man" and "The Cave" defined the arena-folk sound the Sons popularised. On the album's tempestuous opening track, Marcus Mumford exclaims, "Love, it will not betray, dismay or enslave you/It will set you free". That's the band's guiding ethos, teed up right from the start.
Sigh No More (Deluxe) [3 Video Version] Mumford & Sons
Sigh No More
Winter Winds
Roll Away Your Stone
White Blank Page
I Gave You All
Little Lion Man
Thistle & Weeds
Awake My Soul
Dust Bowl Dance
Little Lion Man (Bookshop Acoustic Session)
Winter Winds (Bookshop Acoustic Session)
Released: 5 Oct 2009
℗ 2009 Mumford & Sons, Under exclusive license to Universal Island Records Ltd. A Universal Music Company
Babel (Deluxe)
Johannesburg - EP
Mumford & Sons, Laura Marling & Dharohar Project - EP
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Classical(6)
Biography(4)
Contemporary Classic(3)
General Music(1)
Bartok(14)
Leafstedt(2)
Antokoletz(1)
Bartok Records (Hl) (2)
Ashgate (1)
Audite Records (1)
Royal Music Association Monographs(1)
Bartok Bluebeard
Duke Bluebeard's Castle : Opera In One Act To The Libretto by Bela Balazs.
Bartok, Bela,
Publisher: Bartok Records (Hl)
With a preface in English and Hungarian. Critical notes in English. One black & white photo. With a singing translation in English by Peter Bartok. Composed in 1911, this was Bartok's first composition for the stage.
With a preface in Hungarian and English. Critical notes in English. With a singing translation in English by Peter Bartok. Corrected edition prepared by Peter Bartok and Peter Hennings. Although composed in 1911, this work was not premiered until 1918.
Bluebeard's Castle, Op. 11 : [G/E].
Publisher: Boosey & Hawkes
UE13641 Text by Belá Balasz. German and English text.
Bluebeard's Castle, Op. 11 : Opera In One Act, Text by Belá Balasz.
Inside Bluebeard's Castle : Music and Drama In Bela Bartok's Opera.
Leafstedt, Carl S.
Carl S. Leafstedt is Assistant Professor of Music at the University of North Carolina at Greensboro. First book-length examination of Bartok's 1911 opera includes : music-dramatic analysis, literary study of libretto, Hungarian cultural context. B&W ill, Appendix, Notes, Selected Bibliography,…
Bluebeard's Castle. [CD]
Publisher: Sony Music Entertainment
Columbia’s 1960 recording of Bartok’s Bluebeard’s Castle. Eugene Ormandy conducts the Philadelphia Orchestra.
Publisher: Chandos
With Michelle De Young; John Relyea; and the Bergen Philharmonic Orchestra. Conducted by Edward Gardner. Hybrid SACD.
Bluebeard's Castle, Op. 11.
Publisher: Dover Publications
Reprint of original Univeral Edition, 1921. Piano reduction by Bartok. Text in German and Hungarian. Libretto by Bela Balazs. Dover edition includes cast of characters, instrumentation, introduction by Stanley Appelbaum, and a synopsis.
Bluebeard's Castle. [DVD]
Publisher: Decca Records
London Philharmonic, Sir Georg Solti, conductor.
Duke Bluebeard's Castle. [CD]
Publisher: Signum Records
With Sir John Tomlinson and Michelle DeYoung. Esa-Pekka Salonen conducts the Philharmonia Orchestra.
Publisher: Audite Records
A previously unreleased recording from the 1962 Lucerne Festival. Featuring Irmgard Seefried and Dietrich Fischer-Dieskau. Conducted by Rafael Kubelik.
Duke Bluebeard's Castle. [DVD]
Publisher: Kultur Video
A 1989 film version starring Robert Lloyd and Elizabeth Laurence. Adam Fischer conducts the London Philharmonic.
Bluebeard's Castle; Cantata Profana. [CD]
Publisher: Praga Records
With soprano Pudith Hellwigh and bass Endreh Koreh. Walter Süsskind conducts the New Symphony Orchestra of London.
Bluebeard's Doors : A Song Cycle For Soprano and Piano.
Nelson, Robert,
Publisher: Classical Vocal Reprints
A song cycle on texts by Lynda Lacy, and based on the story of Bluebeard and Bartok's opera on the subject. Premiered by sopranos Cynthia Vaughn and Claudia White. With a program note.
Bluebeard's Castle : Opera In One Act. [CD]
This recording of Bartok's opera features Gustav Belacek as Bluebeard, and Andrea Melath as Judith. Marin Alsop conducts the Bournemouth Symphony Orchestra.
Bluebeard's Castle, Op. 11 / 1963 Revision by Fuessl/Wagner.
Opera in one act by Bela Balasz. Hungarian and Geman text; German version by Wilhelm Ziegler.
Musical Symbolism In The Operas Of Debussy and Bartok : Trauma, Gender & The Unfolding Unconscious.
Antokoletz, Elliott.
The author examines the relationship of new musical ideas to the symbolist librettos of Debussy's Pelleas et Melisande and Bartok's Bluebeard's Castle. With the collaboration of Juana Canabal Antokoletz. With a preface, notes, bibliography, index and music examples.
Bartok and The Grotesque : Studies In Modernity, The Body and Contradiction In Music.
Brown, Julie.
Publisher: Ashgate
Series: Royal Music Association Monographs
, Vol. 16
The author studies works by Bartok which focus on the grotesque, such as Bluebeard's Castle, The Wooden Prince, The Miraculous Mandarin and Cantata Profana. With an introduction, bibliography, index, figures, music examples and one table.
Barbie Blue; Gulliver In Faremido; Conversations With Children. [CD]
Vajda, Gergely,
Publisher: Budapest Music Center
This disc features Barbie Blue, a comic take on Bartok's opera, Duke Bluebeard's Castle. Various artists.
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Sullivan County Commission
Sullivan looking at cell phones for county commissioners
J. H. Osborne • Jan 15, 2020 at 5:30 PM
BLOUNTVILLE — A proposal to provide publicly funded cell phones to Sullivan County’s 24 commissioners, the county attorney and the county mayor is on the agenda for the Sullivan County Commission’s meeting Thursday.
Sponsored by Commissioner Hunter Locke and Commissioner John Gardner, the proposal would cost $1,039.74 per month.
That’s based on a monthly rate plan option through FirstNet, which Locke said provides cell phone service for first response emergency workers across the state. The total monthly cost is for 26 phones at $39.99 each per month. Locke said the plan through FirstNet would allow the county to be month-to-month rather than having to enter into an annual contract.
Locke and Gardner’s proposal comes a month after County Attorney Dan Street spoke to the commission about using their private email addresses or electronic devices, such as cell phones. Street said he wanted to make sure commissioners were aware any communications regarding county business are considered public. That means they are subject to requests from the public to review such communications.
Street said the number of such public requests is on the increase and likely to continue to grow. He told commissioners the best option is simply not to conduct county business on personal devices.
Locke said the proposal for county-issued cell phones aims to make that easier.
Commissioner Hershel Glover asked if having a county-issued cell phone would mean his personal cell phone wouldn’t be subject to also being taken in the event of a public records request for his communications involving county business.
Street said if commissioners continue to use their private cell phones for county business, then their cell phones would still be “exposed.” But he also explained that doesn’t mean anyone could physically take the phone.
“It’s what’s on the phone,” Street said.
The Sullivan County Commission is scheduled to meet Thursday at 6 p.m on the second floor of the historic Sullivan County Courthouse.
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Get help now: Call 1-800-686-2646 or text NAMI to 741741 namiohio@namiohio.org
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Advocacy in Action: NAMI Brown County
by Katie Dillon | Apr 9, 2019 | Stories of Inspiration
Written By: Alan Johnson, NAMI Ohio Contract Writer
Danei Edelen was a nervous wreck the day she was to return to work after having a mental health crisis that required hospitalization.
“I was so scared. I laid out all my clothes and took a shower the night before to be as ready as possible. I woke up extra early to have time to ‘just be ready,’ she wrote.
On the way to work, she thought, “What am I going to say to these people? ‘Hi! I just had a psychotic break, what’s going on in your life?’”
She worried what her new co-workers would say around the coffee pot, if they would think of her like a patient from One Flew Over the Cuckoo’s Nest.
But minute by minute, day by day, month by month, Edelen regained her confidence and footing on the job and in life in general.
Now she is executive director of the Brown County chapter of the National Alliance on Mental Illness Ohio. She helped create the NAMI affiliate a year ago in the rural county with few mental health service providers, but people with needs like everywhere else in the state.
“I am a thoroughly middle class mother in the heartland of Ohio,” she said “This is who I am. I was angry at the world for an extremely long time. I would verbally lash out.”
But with the help of medication, counseling, and the support of family and friends, Edelen is doing the work she wants to do – helping and inspiring others. Her seven-year journey from a breakdown to the present was bumpy, she said. She felt alone and isolated at first.
“When you walk off that psych ward, it’s like there is this red cloak with every word for crazy written on it.”
Edelen said it’s vital that people get connected to mental health providers and to NAMI. “You are not alone. That is the message,” she said
Deanna Vietze, executive director of the Brown County Board of Mental Health & Addiction Services, said Edelen came to her with the idea of forming a NAMI chapter. “The way she found NAMI was very positive,” Vietze said. “She wanted to help others.”
“She’s able to share her story and give others the hope it’s not a death sentence, that you can overcome and be a functioning member of society. It gives them a voice. They know when they’re going through something she’s been there as well.”
Vietze said rural Ohio has the same mental health issues as urban areas, but fewer resources and a problem with transportation.
On top of those concerns, people in Appalachian Ohio “learn you pull yourself up by your bootstraps. You don’t go to others for help. That often means there are families with years of untreated mental illness,”
Edelen, who lives with her husband on 13.5 acres in Brown County, is devoted to helping end the stigma of mental illness by speaking out.
“Silence does not aid understanding,” she wrote. “That is why I have come ‘out of the closet’ about my mental illness. That is why I am a presenter for the National Alliance on Mental Illness. I am committed to ending the silence.”
Open Position: Director of Public Policy and Advocacy
Elevating mental health on the world stage
NAMI Wood County – Volunteer Program
Suicide Rates Among Ohio’s Youth and Elderly Jumped Over Last Decade, Report Shows
Recovery Requires a Community Program has Expansion
All content © 2018 | NAMI Ohio
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Brad Pitt's 'Make it Right' foundation faces lawsuit over degradation of New Orleans homes
Ron Austin says residents have reported sicknesses and headaches, in addition to infrastructural issues
In this Dec. 1, 2008, file photo, Brad Pitt walks in the Lower 9th Ward between a home built by the Make It Right Foundation and a FEMA trailer in New Orleans.Alex Brandon/AP Photo
NEW ORLEANS — An attorney plans to sue actor Brad Pitt’s foundation over the degradation of homes built in an area of New Orleans that was among the hardest hit by Hurricane Katrina.
Ron Austin tells WWL-TV he plans to bring a lawsuit on behalf of some Lower Ninth Ward residents against Pitt’s Make It Right foundation. Austin says residents have reported sicknesses and headaches, in addition to infrastructural issues.
Austin says Make It Right “was making a lot of promises to come back and fix the homes that they initially sold these people and have failed to do so.” The report didn’t indicate how many residents would join the lawsuit.
More than 100 “green” Make It Right houses were built in 2008. The foundation didn’t respond to the station’s request for comment.
Angelina Jolie says she thought making a movie with Brad Pitt would save their marriage
Shania Twain finally explains why she name drops Brad Pitt in ‘That Don’t Impress Me Much’
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info@nmscranton.org
2019 Open House
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In 1971, a group of Jesuits opened a middle school in the Lower East Side of Manhattan to serve the waves of Dominican and Puerto Rican immigrants settling in the area. The Nativity Mission Center provided their middle school-aged boys with an educational program in which they could excel academically, socially, and spiritually. The extended school day almost doubled that of the local public school, a low student-to-teacher ratio ensured time for one-on-one instruction, and a summer academic program extended learning year round. They made a commitment to support their graduates through high school and guide them on to college.
Ultimately, it became the inspiration for other educators seeking to provide outstanding education to urban students. More than 60 schools in 27 states operate today serving more than 4000 students.
In 2012, the provincial leaders of the religious congregations within the Diocese of Scranton endorsed an innovative educational project, involving collaboration among several religious congregations. The provincial leaders of interested congregations appointed a task force to investigate this idea and formulate a plan to meet the academic and social needs of low-income middle school children. Utilizing the successful Nativity School model and adapting it to meet the specific needs of the area, the vision for NativityMiguel School of Scranton was born.
No individual religious community had the resources to undertake such a project alone, so it became a collaborative effort among six religious congregations with long traditions of service to Scranton.
The school seeks to provide a holistic, financially accessible and integrated education to students of all faiths who are in grades five through eight and whose potential is under-served because of academic, social and financial challenges. Through the shared commitment of community and educational leaders, the school offers an academically rigorous, extended-day, year-round program which empowers students to greater achievement in high school, college and future employment.
Address: 2300 Adams Ave
E-mail: info@nmscranton.org
NativityMiguel School of Scranton added 12 new photos — in Scranton, Pennsylvania.
More Pictures from the Rope Runner Competition held over the weekend. #Girlscouts ...
NativityMiguel School of Scranton
NativityMiguel is on a 2 hr delay today, Friday, January 17. ...
© , NativityMiguel School Scranton | All Rights Reserved | Built By Center City Print.
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Nostalgic Kick: Why U2’s 1987 rock monster ‘Bullet The Blue Sky’ is still quite up to date
Photo by Anton Corbijn
Turns out the more political material on 'The Joshua Tree' is still quite important 30 years later.
There are multiple ways on how the forthcoming presidency of Donald J. Trump can affect you. Some might tend to loose all hope and isolate themselves from any political subjects, others will stand up and fight against the oppression in a more active way. Some artists might get a new political self-understanding while others are spontaneously dropping all current plans. The second part is apparently what Bono and U2 did and what forced them to take another look at their legendary best-selling 1987 album The Joshua Tree. They are even heading onto a big 30th anniversary tour this summer (which is already pretty mich sold-out), playing the record in its entirety for the very first time. It’s kind of an interesting move for a band that’s been trying so desperately to stay relevant in the past years while ultimately failing to do so in the end.
U2 are finally embracing their age and legacy status, so what happened? Well, obviously Donald Trump happened. While the band has been working for way too long on their new Songs Of Exprience album the world took a quick and slightly bad turn in 2016 and since it’s about time to save the planet again you can bet your favourite sunglasses that Bono will jump on that bandwagon. Look, I get it, U2 are a tricky band, Bono remains a discussable character and The Joshua Tree isn’t quite a cool album (We all know that 1991’s Achtung Baby is way better anyway, right?) but then there’s a track like Bullet The Blue Sky which hasn’t lost its power and – unfortunately – relevance over the past thirty years.
Placed at the fourth position within The Johsua Tree this almost industrial like blues rocker gives the album a surprisingly hard twist at this point (after all it comes directly after With Or Without You). It’s a dirty and grim reckoning with the conservatice United States under Ronald Reagan in the 1980s. Bono criticizes the country’s thirst for war and political corruption while even getting biblical in his rant.
You plant a demon seed
You raise a flower of fire.
We see them burnin’ crosses
See the flames, higher and higher.
Bullet The Blue Sky is a mighty monster against nationalism and militarism and in that form one of U2‘s strongest statements, one that hasn’t lost its meaning. During a show shortly before Trump’s election last year the group performed it as a directly addressed ode to Trump. You can see bootleg footage of it below and a better version of Bono’s ‘dialog’ with the king of Tweets right here.
A lot on The Joshua Tree is lyrically connected to this conservative and anti-liberal period of time in the USA and also the UK under Thatcher 30 years ago and according to the four-piece the current, almost extremer cirumstances ‘forced’ them to get these songs back on their agenda. It’s probably a bit sad to see that we haven’t come that far as a society in the past decades as we hoped for but it’s never too late. So, whether you are joining Bono’s reflective look back or not but sitting still is no option anymore. ‘Outside is America’ … and the rest of the world as well. Don’t forget that.
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By Michael Pearl
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Just five hundred and fifty-four years ago, if you wanted a copy of the Bible, you had to hire a scribe to write it by hand and bind it. Can you imagine how many months or years it would take to produce just one Bible? When I was in high school, I hand-printed the 139th Psalm on a piece of sheepskin leather, very similar to that used by scribes during the Biblical era. It took me several days. My daughter still has it.
In 1439, when Gutenberg invented movable type and a mechanical printing press, his first major project was the Bible, completed in 1455. Gutenberg’s printing technology spread rapidly throughout Europe. Christians were the first to see the potential and employed the new technology. Greek Bibles were printed as well as English ones. Knowledge became the domain of the many, instead of the wealthy few. Understanding garnered from the printed page turned on a light that had long been shaded from the common man.
Seventy-eight years later, knowledge of the Bible had become more common, spawning the greatest revival of all time—the Protestant Reformation. Christians remained on the cutting edge, producing literature in abundance, sweeping Europe and America with literacy and knowledge of God, producing great waves of evangelism and Bible translations into languages of peoples who had never heard the Gospel of Jesus Christ.
Little changed until the invention of radio, when once again Christians saw the potential and employed the marvelous new technology to reach across this land into the most remote of places with good Bible teaching.
Then along came Thomas Edison and his invention of the light bulb, followed by his invention of the moving picture camera, capturing minds and imaginations, and, in just a few decades, along came a television into practically every home.
At first Christians didn’t see the need to employ the new methods of communication. When they did, it was sometimes laughable. I can remember watching “Christian movies” in church 40 years ago and wondering where they found such bad actors and boring story lines. Did you ever see “The Greatest Story Ever Told”? Jesus and the disciples looked like wax figures being slowly moved across the screen.
Twenty years ago no one had heard of “Desktop Publishing.” It still cost a fortune to get something ready for print. And now, here we are, well into the twenty-first century, with unbelievable capabilities—computers, printers, the web, digital cameras, video editing and more.
Fourteen years ago, this ole hillbilly, with no capital at all, borrowed $2,000 from a relative and began a publishing ministry that now prints books in over 30 languages, with another 40 languages in the works. No Greater Joy Ministries is reaching millions of people around the world, including Muslims in Saudi Arabia and Iran. How can we do this? Cutting-edge technology.
I speak to 50 people on Sunday mornings, and before the week is out, thousands have listened to and viewed the message. In time, tens of thousands and hundreds of thousands will hear that one message from the Word of God.
I am not bragging, nor is it my purpose to give you the testimony of our ministry. I am asking a revolutionary question: Why is the church still confined to its expensive buildings, performing worship for the same crowd week after week, sending paltry sums to missionaries doing missions as usual, the way it was done 400 years ago? One man, at great expense, will go into a population of millions, and during his lifetime will never communicate with more than two or three thousand people.
Why has the church been so slow to embrace the modern mode of communication? Our presence should be dominating the digital space. Bible stories should be told by the best actors and with cutting-edge special effects. Countries like Thailand, Vietnam, and Cambodia should be flooded with the Christian message by means of Radio, Television, Newspapers, Magazines, Novels, DVDs, and Web Sites that dazzle the imagination—not at all forgetting Bibles and Christian literature in the language of the people. There is no reason why one mega church could not completely evangelize an entire Asian country in just one year. If all the Born-Again churches in America were to spend most of their money over a period of one year on evangelism, every soul on the planet would hear the gospel at least once, and most would be thoroughly inundated with the good news. The normal yearly gifts and offerings of 10,000 Christians could reach an entire Asian country—something we have never done in the history of the church. Instead of being the last with the least, we should be the first with the most.
Let us forget about building ministries and get back to building the kingdom instead. We have the tools. The church has the money. And we clearly have the commission to do so. We just need the vision.
Jesus told what must happen before he can return to the earth: “And the gospel must first be published among all nations” (Mark 13:10). Did you note the word “publish”? There are many ways to publish abroad the good news of the Gospel of the Kingdom. Let us avail ourselves of every conceivable method to the fullest—till he come.
NGJ Magazine: May-June 2009
A Special Day
Healthy Again
Response from Bill Gothard
The Good and Evil Translation Project Moves Forward with 2 New Opportunities!
The Heart of a Joyful Mom
Husbands and Wives in the Making
How to Get Kids to Remember
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Molar Mic puts a wireless comms system inside the mouth
By Paul Ridden
Molar Mic puts a wireless comm...
The Molar Mic clips to the back teeth and allows for two-way radio communications
Sonitus Technologies
Back in 2010, a company called Sonitus Technologies introduced a novel hearing aid called the SoundBite. The system married a behind-the-ear microphone unit with a custom made clip for inside the mouth that sent tiny vibrations to the inner ear which were translated into sounds. The latest communication aid from the company has attracted the attention of the US Department of Defense, which has awarded Sonitus a contract to develop a wireless two-way comms system that clips to a user's back teeth.
Dubbed the Molar Mic by the US Air Force, which will be the first to deploy the system at the close of the first multi-year, multi-million dollar development stage, the system has been designed to facilitate clear incoming and outgoing voice communication no matter the wearer's operating environment, eliminating the need for external headsets and trailing wires.
"The voice interface sustains communications in dangerous and challenging environments," said the Sonitus CEO Peter Hadrovic. "The Molar Mic is the first in our family of solutions that conventional approaches are unable to address."
Early prototypes of the Molar Mic system have already undergone field testing by members of the Air National Guard 131st Rescue Squadron based at Moffett Field in Mountain View, California, including use in Houston during Hurricane Harvey last year.
The patented audio interface combines a small waterproof microphone and a bone conducting transducer in a custom-fit, battery-powered mouthpiece that's snapped around a wearer's back teeth. The mouthpiece turns incoming audio into vibrations on the molars, which the inner ear translates into sounds that appear to be coming from inside the head, while allowing external sounds to be heard at the same time.
"The placement on the teeth uses the body itself to block external noise when speaking and leverages the user's teeth and jawbone to create a new auditory path for hearing," explained the company in a press release. The mouthpiece links via near-field magnetic induction technology to a tactical neckloop, which is itself connected to a radio. A wireless remote mimics the push-to-talk action of the radio.
The roll out to US Air Force personnel is expected to be followed by other branches of the US defense community. Sonitus says that the system is also being evaluated for use by security personnel, first responders and industrial workers.
Source: Sonitus Technologies
TelecommunicationsWirelessAudioCommunicationsBone ConductionRadio
Paul Ridden
While Paul is loath to reveal his age, he will admit to cutting his IT teeth on a TRS-80 (although he won't say which version). An obsessive fascination with computer technology blossomed from hobby into career before hopping over to France for 10 years, where he started work for New Atlas in 2009. Now back in his native Blighty, he serves as Managing Editor in Europe.
Kpar October 25, 2018 01:37 PM
The next step should be using body heat to charge the device.
EZ January 24, 2019 06:02 PM
What happens if you're eating a burger and "oops."
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HARMAN Named Finalist for Five 2014 Telematics Update Awards
April 21, 2014 Connected Car
STAMFORD, CT –HARMAN, the premium global audio and infotainment group (NYSE:HAR), is a finalist in five categories of 2014 Telematics Update Awards. Driven by its leadership in navigation, connectivity, safety and security features, and cloud-based innovation, HARMAN tops the list as the Tier 1 supplier with the most nominations.
The HARMAN solutions included on the shortlist for the Telematics Update Awards are:
HARMAN’s ConnectedDrive solution for BMW (Best Navigation Solution) - As part of BMW’s latest electric vehicle series the i3 and i8, HARMAN’s ConnectedDrive delivers an all-electric car for daily use with innovative mobility services. At the centerpiece of BMW i Navigation Professional is the Driving Range Assistant with server-based calculated dynamic range map, which takes into account all factors that are important for route navigation: battery charge level, driving style, traffic conditions and topographic nature of the route, not just simply the distance to a destination. The system’s ability to manage battery life on an electric vehicle is unique to the market and gives consumers the easiest and most convenient driving experience as possible.
HARMAN Aha Cloud Platform (Industry Newcomer Award) - Recently unveiled at CES 2014, the HARMAN Aha Cloud Platform allows automakers to easily upgrade existing infotainment and audio systems to extend the lifespan of vehicles, giving the ability for drivers to upgrade in-car audio and infotainment systems, connect to cloud-based content more easily and consistently improve embedded software features.
Aha Radio by HARMAN (Best Telematics Content Aggregator) -Aha Radio seamlessly organizes and integrates your favorite content from the web into personalized, live and on-demand radio stations, bringing everything users love about the web into their cars.
HARMAN’s iOnRoad technology (Best Telematics Safety and Security Technology and Best Automotive Application) - iOnRoad offers automakers a suite of driving assistance functions including augmented driving, and collision and lane departure warnings. iOnRoad technology does not require dedicated hardware and runs on a variety of software platforms including Android, iOS, Windows, and Linux, strengthening HARMAN’s leadership in global infotainment systems.We are thrilled to be named as a finalistin five separate categories for this year’s Telematics Update Awards,” said Sachin Lawande, president, Infotainment Division at HARMAN. “These nominations further demonstrate our ability to push the boundaries of innovation in the car while continuing to disrupt the automotive industry for the benefit of consumers.”
Winners will be announced at the Telematics Update Awards Ceremony on June 3 in Detroit, Michigan prior to the start of Telematics Detroit 2014.
HARMAN (www.harman.com) designs, manufactures, and markets a wide range of infotainment and audio solutions for the automotive, consumer, and professional markets. It is a recognized world leader across its customer segments with premium brands including AKG®, Harman Kardon®, Infinity®, JBL®, Lexicon®, and Mark Levinson® and leading-edge connectivity, safety and audio technologies. The Company is admired by audiophiles across multiple generations and supports leading professional entertainers and the venues where they perform. More than 25 million automobiles on the road today are equipped with HARMAN audio and infotainment systems. HARMAN has a workforce of 14,800 people across the Americas, Europe, and Asia and reported sales of $4.7 billion for the last twelve months ended December 31, 2013.
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Photography changed a woman’s path in life
By Eileen Buckley • Feb 6, 2019
An award-winning local photographer has created a new exhibit called Through The Lens: “Warriors" now on display at CEPA Gallery in downtown Buffalo. WBFO's senior reporter Eileen Buckely sat down with Aitina Fareed-Cooke, the owner & creative director of Get Fokus'd Productions, who selected eight stories about people who beat the odds, just as she did.
Aitina Fareed-Cooke, Owner & Creative Director of Get Fokus'd Productions.
Credit WBFO News photo by Eileen Buckley
WBFO's senior reporter sat down with Aitina Fareed-Cooke, Owner & Creative Director of Get Fokus'd Productions.
Fareed-Cooke was once told she was going to fail, but her very difficult personal struggles and mental anguish taught her to persevere and has inspired her work as a photographer and video artist.
"I lost my mother when I was three years old. She died from a drug overdose," said Fareed-Cooke. "I was labeled a failure to thrive, because my mother had this drug abuse problem while I was in her womb."
Aitina Fareed-Cooke’s exhibit is on now through February 23, 2019 at the CEPA Gallery. It was the CEPA Gallery were she discovered and feel in love with photographer as a teenager. She credits community programs and her faith in God in changing her path and bringing her a successful career.
Aitina Fareed-Cooke
Through The Lens: “Warriors"
CEPA Gallery
Get Fokus'd Productions
African-American artist
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The Pentagon Can ID Your Heartbeat Using Laser Beams
Kyle Mizokami
Popular Mechanics June 27, 2019
Photo credit: Scott Olson - Getty Images
From Popular Mechanics
The Pentagon has developed a new means of identifying people in conflict zones: laser beams.
The Jetson prototype, developed for U.S. special forces, bounces a laser beam off a person to read their unique heartbeat signature, IDing them in seconds. The system is 95 percent accurate and can be used at distances of at least 200 meters, making them useful at locations such as military checkpoints (pictured above) and elsewhere.
In the field, American special forces troops frequently must keep track of large numbers of individuals living and working in their operating areas. These could be intelligence assets, known terrorists, or even just civilians. U.S. military personnel must be able to identify these people quickly and efficiently, and the threat of suicide bombers and insider attacks means the farther away and more discreetly they can ID them, the better.
The new biometric sensor works by bouncing a laser beam off a human target. The method, called laser vibrometry, measures the target’s heartbeat off the surface of the skin. Each person’s heartbeat is slightly different, making it possible to identify people by the surface movement caused by the heartbeat. The laser can even read a heartbeat through layers of clothing.
The process of identifying a person from a distance is called remote cardiac sensing. Supporters say it’s more effective than other means. Facial recognition can be defeated by wearing sunglasses or a disguise to break up the person’s facial profile. Gait analysis, or identifying someone through their physical profile while walking, could be defeated by someone aware he or she is being monitored and actively changing their gait. But it's very difficult, if not impossible, to modify your own unique cardiac rhythm.
Cardiac sensing isn’t perfect, as it requires 30 seconds of laser contact for a successful reading. It also requires the subject to be sitting or standing. But it is 95 percent successful, and the Pentagon thinks it could be accomplished at ranges greater than the existing 200 yards. Ultimately, it appears likely that troops would use multiple sensing methods, each covering the weaknesses of the other, to achieve positive identification in the field.
Source: MIT Technology Review
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NewsAutoTop
New 2020 Porsche Taycan: interior teased
The all-electric Porsche Taycan will feature the world’s first infotainment system with fully integrated support for Apple Music
Porsche has released a teaser image of the forthcoming, all-electric Taycan’s dashboard, ahead of the car’s scheduled launch at this year’s Frankfurt Motor Show. The Taycan will be the German brand’s first all-electric vehicle, which, when it goes on sale in 2020, will go head-to-head with the Tesla Model S.
The Porsche Taycan will be the world’s first vehicle with full integration for Apple Music and, as such, its infotainment system will feature a range of unique functions. For example, the car’s voice control function has been reconfigured, allowing owners to seamlessly search for songs, albums and playlists on Apple Music.
• Best electric cars on sale
All Taycans will come with a free six-month subscription to Apple Music and a complimentary three-year roaming internet connection. Buyers will also gain access to a range of exclusive Apple Music playlists, curated by Porsche for Taycan owners, while a high-quality Burmester surround sound system can be specced as an optional extra.
Like earlier prototypes, this image shows the production-ready Taycan will adopt a freestanding digital instrument display and a large infotainment screen, similar to the 10.1-inch unit used by Audi. When Porsche releases a set of less restrictive images, we also expect to find a small toggle-style gear selector and a second touchscreen display for the centre console, which will likely be used to operate the climate control system.
Porsche’s latest Taycan development mule recently completed a 24 hour endurance test at the Nardo test track in Italy. During the run, a team of six Porsche development drivers covered 3,425km (2,128 miles), averaging between 121mph and 134mph, with only a handful of stops for recharging and driver changes.
The pictured prototype still wears an intricate livery, so little more can be gleaned about the car’s styling. Our most recent spy shots provide a better indication of the Taycan’s design, revealing a surprising amount of 718 Boxster and Cayman influence at the front end. Smaller details, such as the retractable door handles, could also be picked out.
Porsche isn’t giving much away about the Taycan’s exact specifications, but we understand there will be multiple variants (with differing power outputs), but that range-topping cars will feature two electric motors, one on each axle, producing over 600bhp. The PSM motors are derived from Porsche’s Le Mans-winning 919 LMP1 car, the marque claiming that the key advantage offered by PSM is compact packaging and weight saving.
Charge will be provided by a lithium-ion battery pack denser than anything Tesla currently offers, rated at 270 watt-hours per kilogram, and Porsche is targeting over 310 miles on a single charge. It’s claimed that the 800-volt system can take on 62 miles of charge in just four minutes, or almost 250 miles in 15 minutes.
Of course, these figures are entirely dependent on the availability of 350kW CCS chargers compatible with Porsche’s 800v system. Currently, the IONITY network is expanding throughout Europe and building chargers capable of delivering such voltages. Porsche also has plans to deploy 500 of its own chargers across the United States in the coming years.
The 600bhp-plus Taycan is expected to be the flagship model, but additional variants of the car, of which there is likely to be three, will vary from around 400bhp up to 600bhp. Porsche CEO Oliver Blume told us: “We will think of different options and there will be more than one, with different levels of power.”
All-wheel drive is expected to be standard on all versions initially, but it’s possible that Porsche will launch a more affordable rear-wheel-drive edition in the future. Over-the-air updates will also be possible on the Porsche Taycan, upgrading on-board infotainment systems and safety tech, but also offering to boost power if the customer wishes.
Hands on with the Porsche Taycan prototype
Earlier in the Porsche Taycan’s production cycle, Auto Express was granted access to early prototypes. The prototypes, which were being prepared to join Porsche’s intensive development programme, were being hand-assembled by a team of workers at a rate of two per day.
Porsche’s Director for the Taycan’s Complete Vehicle Model Line, Robert Meier, described the Taycan’s four-door saloon format is described as a “four plus one” with space for luggage front and rear, while the driving position is “almost identical to the 911.”
Initially, the annual Porsche Taycan production output will be between 20,000 and 25,000 units. “We are capable of ramping up our production capacity substantially if demand exceeds expectations,” said Meschke. “We will be able to ship significant numbers in the coming years,” he added.”
According to Porsche, Taycan is a word taken from an eastern dialect and is pronounced ‘tie-can’. It translates as ‘lively young horse’ and is a reference to the horse that’s been rearing up on its hind legs on the Porsche badge since 1952.
Taycan Sport Turismo spied – and more Porsche EVs to follow
Porsche will also expand the Taycan’s line-up with the Taycan Sport Turismo. A battered-looking mule for the all-electric estate has already been spotted undergoing testing at the Nurburgring. We expect it’ll feature the same drivetrain as the saloon, but its styling will be heavily revised with a shooting-brake style extended cabin.
The German firm has also previously confirmed the E-Cross Turismo Concept will reach production. It’ll feature the same estate-styled body as the Sport Turismo, with a range of crossover touches like a raised ride height and rugged exterior cladding.
Finally, Porsche bosses have revealed a fully electric SUV is likely to follow the Taycan trio into showrooms. Meschke told Auto Express: “Expect an SUV BEV (battery electric vehicle) by 2022 at the latest.”
The SUV could make use of the VW Group’s MEB platform that will debut on the forthcoming VW ID. hatchback. Alternatively, a shortened version of the J1 platform underpinning the Taycan could be used. “By 2030 the traditional Porsche could be a niche offering,” Meschke added.
Which do you prefer, the Porsche Taycan or the Tesla Model S? Let us know in the comments section below…
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"Clusterization" and intermittency of temperature fluctuations in turbulent convection
A. Bershadskii, J. J. Niemela, A. Praskovsky, K. R. Sreenivasan
Mechanical and Aerospace Engineering
Center for Space Science
The clusterization and amplitude intermittency of temperature fluctuations in turbulent convection were investigated. The temperature time traces were obtained in turbulent thermal convection at high Rayleigh numbers. A telegraph approximation for temperature traces were generated by setting the fluctuation amplitudes to 1 or 0, which allowed to distinguish the tendency of events to cluster from their large-scale variability in amplitude. The telegraphic approximation is useful because of the specific process of heat transfer, which was determined in large measures by the random motion of temperature plumes.
Physical Review E
Intermittency
Thermal Convection
Rayleigh number
free convection
Bershadskii, A., Niemela, J. J., Praskovsky, A., & Sreenivasan, K. R. (2004). "Clusterization" and intermittency of temperature fluctuations in turbulent convection. Physical Review E, 69(5 1), [056314].
"Clusterization" and intermittency of temperature fluctuations in turbulent convection. / Bershadskii, A.; Niemela, J. J.; Praskovsky, A.; Sreenivasan, K. R.
In: Physical Review E, Vol. 69, No. 5 1, 056314, 05.2004.
Bershadskii, A, Niemela, JJ, Praskovsky, A & Sreenivasan, KR 2004, '"Clusterization" and intermittency of temperature fluctuations in turbulent convection', Physical Review E, vol. 69, no. 5 1, 056314.
Bershadskii A, Niemela JJ, Praskovsky A, Sreenivasan KR. "Clusterization" and intermittency of temperature fluctuations in turbulent convection. Physical Review E. 2004 May;69(5 1). 056314.
Bershadskii, A. ; Niemela, J. J. ; Praskovsky, A. ; Sreenivasan, K. R. / "Clusterization" and intermittency of temperature fluctuations in turbulent convection. In: Physical Review E. 2004 ; Vol. 69, No. 5 1.
@article{df6929190cff42adb959ed024c20c363,
title = "{"}Clusterization{"} and intermittency of temperature fluctuations in turbulent convection",
abstract = "The clusterization and amplitude intermittency of temperature fluctuations in turbulent convection were investigated. The temperature time traces were obtained in turbulent thermal convection at high Rayleigh numbers. A telegraph approximation for temperature traces were generated by setting the fluctuation amplitudes to 1 or 0, which allowed to distinguish the tendency of events to cluster from their large-scale variability in amplitude. The telegraphic approximation is useful because of the specific process of heat transfer, which was determined in large measures by the random motion of temperature plumes.",
author = "A. Bershadskii and Niemela, {J. J.} and A. Praskovsky and Sreenivasan, {K. R.}",
journal = "Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics",
number = "5 1",
T1 - "Clusterization" and intermittency of temperature fluctuations in turbulent convection
AU - Bershadskii, A.
AU - Niemela, J. J.
AU - Praskovsky, A.
AU - Sreenivasan, K. R.
N2 - The clusterization and amplitude intermittency of temperature fluctuations in turbulent convection were investigated. The temperature time traces were obtained in turbulent thermal convection at high Rayleigh numbers. A telegraph approximation for temperature traces were generated by setting the fluctuation amplitudes to 1 or 0, which allowed to distinguish the tendency of events to cluster from their large-scale variability in amplitude. The telegraphic approximation is useful because of the specific process of heat transfer, which was determined in large measures by the random motion of temperature plumes.
AB - The clusterization and amplitude intermittency of temperature fluctuations in turbulent convection were investigated. The temperature time traces were obtained in turbulent thermal convection at high Rayleigh numbers. A telegraph approximation for temperature traces were generated by setting the fluctuation amplitudes to 1 or 0, which allowed to distinguish the tendency of events to cluster from their large-scale variability in amplitude. The telegraphic approximation is useful because of the specific process of heat transfer, which was determined in large measures by the random motion of temperature plumes.
JO - Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
JF - Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
IS - 5 1
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